Artocarpus heterophyllus
Species
KNApSAcK Entry
| Organism name | Artocarpus heterophyllus |
|---|---|
| Genus | Artocarpus |
| Family | Moraceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Artocarpus heterophyllus |
|---|---|
| Linked NCBI taxonomy ID | 3489 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Moraceae |
|---|---|
| ID | 3487 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Metabolite list (29)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00003860
|
Artocarpetin
|
CHEMBL460552
|
No. 3 | No. 15 |
|
|||
|
C00013421
|
Heteroartonin A
/ 2-[2,5-Dihydroxy-4-methoxy-3-(3-methyl-2-butenyl)phenyl]-5,7-dihydroxy-3-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one |
No. 14 | No. 15 |
|
||||
|
C00004062
|
Isoartocarpin
/ Cycloartocarpin |
No. 14 | No. 15 |
|
||||
|
C00004032
|
Artocarpin
/ 2',4',5-Trihydroxy-7-methoxy-6-(3-methyl-1-butenyl)-3-(3-methyl-2-butenyl)flavone / 2-(2,4-Dihydroxyphenyl)-5-hydroxy-7-methoxy-6-(3-methyl-1-butenyl)-3-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one |
No. 14 | No. 15 |
|
||||
|
C00004028
|
Mulberrin
/ Kuwanon C / Norartocarpin / 2-(2,4-Dihydroxyphenyl)-5,7-dihydroxy-3,8-bis(3-methyl-2-butenyl)-4H-1-benzopyran-4-one |
CHEMBL518543
|
3 / 0 / 3 | No. 14 | No. 15 |
|
||
|
C00004030
|
Kuwanon T
/ 2-[2,4-Dihydroxy-3-(3-methyl-2-butenyl)phenyl]-5,7-dihydroxy-3-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one |
No. 14 | No. 15 |
|
||||
|
C00013418
|
Artocarpetin B
/ 5-Hydroxy-2-(4-hydroxy-2-methoxyphenyl)-7-methoxy-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one |
No. 15 | No. 15 |
|
||||
|
C00013410
|
Artonin U
/ 5-hydroxy-2-(4-Hydroxyphenyl)-7-methoxy-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one |
No. 15 | No. 15 |
|
||||
|
C00004025
|
Artocarpesin
/ 2',4',5,7-Tetrahydroxy-6-(3-methyl-2-butenyl)flavone / 2-(2,4-Dihydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one |
CHEMBL1915458
|
1 / 4 / 1 | No. 15 | No. 15 |
|
||
|
C00004101
|
Cycloartocarpin A
|
CHEMBL463093
|
No. 18 | No. 15 |
|
|||
|
C00004053
|
Cycloartocarpesin
/ 8-(2,4-Dihydroxyphenyl)-5-hydroxy-2,2-dimethyl-2H,6H-benzo[1,2-b:5,4-b']dipyran-6-one |
CHEMBL221908
|
2 / 0 / 0 | No. 24 | No. 15 |
|
||
|
C00008362
|
Artocarpanone
|
CHEMBL467194
|
No. 25 | No. 14 |
|
|||
|
C00014123
|
5,2'-Dihydroxy-7,4'-dimethoxyflavanone
|
No. 25 | No. 14 |
|
||||
|
C00013460
|
Heterophyllin
|
CHEMBL461821
|
No. 44 |
|
||||
|
C00013481
|
Artonin J
/ 5a,6-Dihydro-1,3,8,10-tetrahydroxy-5,5-dimethyl-2-(3-methyl-2-butenyl)-5H,7H-benzofuro[3,4-bc]xanthen-7-one |
No. 44 |
|
|||||
|
C00004064
|
Cycloheterophyllin
|
CHEMBL461820
|
C107099
|
5 / 2 / 2 | No. 44 |
|
||
|
C00013482
|
Artonin T
/ 5a,6-Dihydro-1,3,8-trihydroxy-10-methoxy-5,5-dimethyl-2-(3-methyl-2-butenyl)-5H,7H-benzofuro[3,4-bc]xanthen-7-one |
No. 44 |
|
|||||
|
C00013504
|
Artonin S
/ (+)-6,7-Dihydro-3,9-dihydroxy-6-(1-hydroxy-1-methylethyl)-11-methoxy-10-(3-methyl-2-butenyl)-8H-[1]benzopyrano[3,2-d][1]benzoxepin-8-one |
No. 47 | No. 15 |
|
||||
|
C00003859
|
Norartocarpetin
|
CHEMBL463145
|
3 / 0 / 3 | No. 71 | No. 15 |
|
||
|
C00008535
|
Heteroflavanone A
|
CHEMBL508961
|
No. 77 | No. 14 |
|
|||
|
C00008079
|
Artonin C
|
No. 81 | No. 20 |
|
||||
|
C00008080
|
Artonin D
|
No. 81 | No. 20 |
|
||||
|
C00008081
|
Artonin I
|
No. 81 | No. 20 |
|
||||
|
C00008082
|
Artonin X
|
No. 81 | No. 20 |
|
||||
|
C00013479
|
Artonin L
/ 5a,6-Dihydro-3,8-dihydroxy-1,10-dimethoxy-5,5-dimethyl-5H,7H-benzofuro[3,4-bc]xanthen-7-one |
No. 139 |
|
|||||
|
C00013480
|
Artonin K
/ 5a,6-Dihydro-1,3,8-trihydroxy-10-methoxy-5,5-dimethyl-5H,7H-benzofuro[3,4-bc]xanthen-7-one |
No. 139 |
|
|||||
|
C00008503
|
Heteroflavanone C
|
No. 765 |
|
|||||
|
C00008505
|
Heteroflavanone B
|
CHEMBL466985
|
No. 765 |
|
||||
|
C00004026
|
Oxidihydroartocarpesin
|
No. 4050 |
|
Human Protein / Gene in interactions
11 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00003859 C00004028 | 0 / 3 |
| P56817 | Beta-secretase 1 | A1A | C00003859 C00004028 | 0 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00003859 C00004028 | 0 / 0 |
| O75908 | Sterol O-acyltransferase 2 | Enzyme | C00004053 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00004064 | 0 / 0 |
| P17405 | Sphingomyelin phosphodiesterase | Enzyme | C00004064 | 2 / 2 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00004064 | 0 / 0 |
| P35610 | Sterol O-acyltransferase 1 | Enzyme | C00004053 | 0 / 0 |
| P31749 | RAC-alpha serine/threonine-protein kinase | Akt | C00004025 | 4 / 1 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00004064 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00004064 | 0 / 0 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (6)
| OMIM | preferred title | UniProt |
|---|---|---|
| #114480 | Breast cancer |
P31749
|
| #114500 | Colorectal cancer; crc |
P31749
|
| #615109 | Cowden syndrome 6; cws6 |
P31749
|
| #257200 | Niemann-pick disease, type a |
P17405
|
| #607616 | Niemann-pick disease, type b |
P17405
|
| #176920 | Proteus syndrome |
P31749
|
KEGG DISEASE (6)
| KEGG | name | UniProt |
|---|---|---|
| H00137 | Niemann-Pick disease (NPD) typeA and B |
P17405
(related)
|
| H00424 | Defects in the degradation of sphingomyelin |
P17405
(related)
|
| H00539 | PTEN hamartoma tumor syndrome (PHTS) |
P31749
(related)
|
| H00017 | Esophageal cancer |
P35354
(related)
|
| H00025 | Penile cancer |
P35354
(related)
|
| H00046 | Cholangiocarcinoma |
P35354
(related)
|