Magnolia denudata

• Index
• Plant Species
• Metabolite list (33)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Magnolia denudata
Genus	Magnolia
Family	Magnoliaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Magnolia denudata
Linked NCBI taxonomy ID	85856
Linked level	species

Family

Family in NCBI taxonomy	Magnoliaceae
ID	3401

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	Magnoliophyta
ID	3398

Metabolite list (33)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00031449	(-)-Methylpiperitol	CHEMBL462822				No. 38	No. 21
C00002631	(+)-Lirioresinol B / (+)-Syringaresinol	CHEMBL361362 CHEMBL402653	C042192	1 / 0 / 0		No. 38	No. 21
C00000640	(+)-Eudesmin	CHEMBL519099 CHEMBL512865 CHEMBL523743 CHEMBL464352 CHEMBL1726879	C105875	2 / 0 / 0		No. 38	No. 21
C00000642	(+)-Yangambin	CHEMBL510536 CHEMBL454592 CHEMBL1412125		4 / 2 / 0		No. 38	No. 21
C00000643	Kobusin / (+)-Kobusin / (+)-Spinescin / Methylpiperitol	CHEMBL462822				No. 38	No. 21
C00030244	Fargesin	CHEMBL462822				No. 38	No. 21
C00007190	(+)-Pinoresinol	CHEMBL267963 CHEMBL487611 CHEMBL460862	C103298	7 / 5 / 6		No. 38	No. 21
C00007212	Galgravin	CHEMBL56800 CHEMBL57542 CHEMBL418309 CHEMBL291515 CHEMBL56856 CHEMBL56917 CHEMBL112481 CHEMBL469500	C084077	1 / 0 / 0		No. 38	No. 21
C00002607	Grandisin / (-)-Grandisin	CHEMBL459404 CHEMBL459405 CHEMBL1377609 CHEMBL2204392	C074346	4 / 3 / 7		No. 38	No. 21
C00002633	(+)-Veraguensin	CHEMBL56800 CHEMBL57542 CHEMBL418309 CHEMBL291515 CHEMBL56856 CHEMBL56917 CHEMBL112481 CHEMBL469500		1 / 0 / 0		No. 38	No. 21
C00032698	Acuminatin / (+)-Acuminatin	CHEMBL571195	C077860			No. 215	No. 23
C00000696	Licarin B	CHEMBL259386 CHEMBL578403	C119225			No. 215	No. 23
C00000601	(+)-Sesamin	CHEMBL43469 CHEMBL252915 CHEMBL1572261 CHEMBL1591714 CHEMBL1708854 CHEMBL1904496 CHEMBL1968861	C054125	20 / 24 / 15	0 / 5	No. 621	No. 21
C00007213	(-)-Galbacin	CHEMBL1980140 CHEMBL2151191		2 / 0 / 0		No. 621	No. 21
C00000602	(+)-Lariciresinol	CHEMBL518421		2 / 1 / 1		No. 700	No. 21
C00032901	Denudatin A	CHEMBL606463				No. 1419	No. 23
C00000671	(+)-Denudatin B	CHEMBL30122 CHEMBL296958 CHEMBL571196 CHEMBL2114380				No. 1419	No. 23
C00031846	Hancinone	CHEMBL606463				No. 1419	No. 23
C00033250	Nirandin A	CHEMBL30352 CHEMBL570291				No. 1419	No. 23
C00032896	Denudadione C					No. 1497
C00032894	Denudadione A					No. 1497
C00032895	Denudadione B					No. 1497
C00031994	Magnolone / (-)-Magnolone					No. 1587
C00033060	Isodihydrofutoquinol B / (+)-Isodihydrofutoquinol B	CHEMBL290066				No. 2047	No. 23
C00033059	Isodihydrofutoquinol A	CHEMBL290066				No. 2047	No. 23
C00002610	Kadsurin A / (+)-Kadsurin A	CHEMBL37432				No. 2788	No. 23
C00032897	Denudanolide A					No. 2876
C00032898	Denudanolide B					No. 2876
C00032900	Denudanolide D					No. 2876
C00032899	Denudanolide C					No. 2876
C00031784	Fargesone B					No. 3583	No. 23
C00001259	Naphthalene	CHEMBL16293	C031721	6 / 5 / 4	43 / 18	No. 5021
C00031639	Burcellin					No. 6551

Human Protein / Gene in interactions

39 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
O75496	Geminin	Unclassified protein	C00000601 C00000642 C00001259 C00002607	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00000601 C00000642 C00007190	0 / 0
P25105	Platelet-activating factor receptor	PAF receptor	C00002633 C00007212	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000601 C00000602	0 / 1
Q9UNA4	DNA polymerase iota	Enzyme	C00000601 C00002607	0 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000601 C00000602	1 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00000640 C00000642	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00000601 C00000642	2 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00000601	0 / 0
P11387	DNA topoisomerase 1	Isomerase	C00002631	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00000601	2 / 3
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00000601	0 / 0
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00001259	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00000640	0 / 0
P42574	Caspase-3	C14	C00001259	0 / 0
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00007190	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00000601	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00000601	7 / 3
P83916	Chromobox protein homolog 1	Unclassified protein	C00000601	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00000601	0 / 1
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00007190	5 / 3
P18054	Arachidonate 12-lipoxygenase, 12S-type	Enzyme	C00001259	2 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00000601	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00001259	0 / 0
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00000601	2 / 2
P45984	Mitogen-activated protein kinase 9	Jnk	C00007213	0 / 0
Q16539	Mitogen-activated protein kinase 14	p38	C00007213	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00000601	1 / 1
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00007190	0 / 3
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00007190	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00000601	4 / 3
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00000601	0 / 0
P10275	Androgen receptor	NR3C4	C00001259	3 / 4
Q07869	Peroxisome proliferator-activated receptor alpha	NR1C1	C00007190	0 / 0
Q16637	Survival motor neuron protein	Unclassified protein	C00000601	4 / 1
O00255	Menin	Unclassified protein	C00002607	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00002607	1 / 2
Q9H0H5	Rac GTPase-activating protein 1	Unclassified protein	C00007190	0 / 0
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00000601	1 / 1

43 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
5243	ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1	ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44)	C00001259
196	AHR, bHLHe76	aryl hydrocarbon receptor	C00001259
429	ASCL1, ASH1, HASH1, MASH1, bHLHa46	achaete-scute family bHLH transcription factor 1	C00001259
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00001259
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00001259
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00001259
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00001259
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00001259
1557	CYP2C19, CPCJ, CYP2C, P450C2C, P450IIC19	cytochrome P450, family 2, subfamily C, polypeptide 19 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00001259
1558	CYP2C8, CPC8, CYPIIC8, MP-12/MP-20	cytochrome P450, family 2, subfamily C, polypeptide 8 (EC:1.14.14.1)	C00001259
1559	CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9	cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00001259
1565	CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1	cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1)	C00001259
1571	CYP2E1, CPE1, CYP2E, P450-J, P450C2E	cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7)	C00001259
13107			C00001259
29785	CYP2S1	cytochrome P450, family 2, subfamily S, polypeptide 1 (EC:1.14.14.1)	C00001259
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00001259
1577	CYP3A5, CP35, CYPIIIA5, P450PCN3, PCN3	cytochrome P450, family 3, subfamily A, polypeptide 5 (EC:1.14.14.1)	C00001259
2052	EPHX1, EPHX, EPOX, HYL1, MEH	epoxide hydrolase 1, microsomal (xenobiotic) (EC:3.3.2.9)	C00001259
2053	EPHX2, CEH, SEH	epoxide hydrolase 2, cytoplasmic (EC:3.3.2.10 3.1.3.76)	C00001259
2252	FGF7, HBGF-7, KGF	fibroblast growth factor 7	C00001259
2353	FOS, AP-1, C-FOS, p55	FBJ murine osteosarcoma viral oncogene homolog	C00001259
2521	FUS, ALS6, ETM4, FUS1, HNRNPP2, POMP75, TLS	fused in sarcoma	C00001259
2642	GCGR, GGR	glucagon receptor	C00001259
2944	GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1	glutathione S-transferase mu 1 (EC:2.5.1.18)	C00001259
8870	IER3, DIF-2, DIF2, GLY96, IEX-1, IEX-1L, IEX1, PRG1	immediate early response 3	C00001259
3565	IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4	interleukin 4	C00001259
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00001259
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00001259
3956	LGALS1, GAL1, GBP	lectin, galactoside-binding, soluble, 1	C00001259
4157	MC1R, CMM5, MSH-R, SHEP2	melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)	C00001259
4159	MC3R, BMIQ9, MC3, MC3-R, OB20, OQTL	melanocortin 3 receptor	C00001259
4160	MC4R	melanocortin 4 receptor	C00001259
4161	MC5R, MC2	melanocortin 5 receptor	C00001259
10403	NDC80, HEC, HEC1, HsHec1, KNTC2, TID3, hsNDC80	NDC80 kinetochore complex component	C00001259
4846	NOS3, ECNOS, eNOS	nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39)	C00001259
5053	PAH, PH, PKU, PKU1	phenylalanine hydroxylase (EC:1.14.16.1)	C00001259
5894	RAF1, CRAF, NS5, Raf-1, c-Raf	v-raf-1 murine leukemia viral oncogene homolog 1 (EC:2.7.11.1)	C00001259
389	RHOC, ARH9, ARHC, H9, RHOH9	ras homolog family member C	C00001259
7356	SCGB1A1, CC10, CC16, CCPBP, CCSP, UGB, UP-1, UP1	secretoglobin, family 1A, member 1 (uteroglobin)	C00001259
6855	SYP, MRXSYP	synaptophysin	C00001259
6932	TCF7, TCF-1	transcription factor 7 (T-cell specific, HMG-box)	C00001259
7076	TIMP1, CLGI, EPA, EPO, HCI, TIMP	TIMP metallopeptidase inhibitor 1	C00001259
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00001259

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions