Erycibe expansa

• Index
• Plant Species
• Metabolite list (18)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Erycibe expansa
Genus	Erycibe
Family	Convolvulaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Erycibe
Linked NCBI taxonomy ID	197385
Linked level	genus

Family

Family in NCBI taxonomy	Convolvulaceae
ID	4118

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Metabolite list (18)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00000960	Eriodictyol	CHEMBL8996 CHEMBL307893 CHEMBL1975989	C007619	32 / 29 / 55	5 / 0	No. 25	No. 14
C00030207	Erycibenin D / (-)-Erycibenin D	CHEMBL241571				No. 42	No. 14
C00003672	Sitosterol / beta-sitosterl / (-)-beta-Sitosterol / Stigmast-5-en-3beta-ol	CHEMBL221542 CHEMBL1398443 CHEMBL1875388		17 / 19 / 12		No. 53	No. 11
C00000674	Luteolin	CHEMBL151	D047311	99 / 91 / 95	76 / 6	No. 71	No. 15
C00030209	Erycibenin F / (-)-Erycibenin F	CHEMBL391981				No. 73	No. 15
C00029556	5,7-Dimethoxy-4'-hydroxyflavan / (+/-)-5,7-Dimethoxy-4'-hydroxyflavan	CHEMBL397828				No. 73	No. 15
C00030208	Erycibenin E / (-)-Erycibenin E	CHEMBL241569				No. 73	No. 15
C00001232	Oleic acid / (Z)-9-Octadecenoic acid	CHEMBL8659 CHEMBL460657	D019301	30 / 19 / 20	26 / 9	No. 184	No. 68
C00030205	Erycibenin B / (+)-Erycibenin B	CHEMBL427693				No. 240
C00030204	Erycibenin A / (+)-Erycibenin A	CHEMBL241817				No. 240
C00002537	Rotenolone / 12a-Hydroxyrotenone	CHEMBL240545				No. 281	No. 15
C00002568	Rotenone / Tubotoxin / Nicouline	CHEMBL429023 CHEMBL267461 CHEMBL418710 CHEMBL1518927	D012402	129 / 92 / 86	177 / 42	No. 281	No. 15
C00001224	Linoleic acid / (Z,Z)-9,12-Octadecadienoic acid	CHEMBL267476		29 / 31 / 28		No. 367	No. 68
C00030206	Erycibenin C / (-)-Erycibenin C	CHEMBL240929				No. 396	No. 15
C00019308	Doursterol / Daucosterin / 3-O-beta-D-Glucopyranosyl sitosterol / beta-Sitosterol 3-O-beta-D-glucopyranoside	CHEMBL197711 CHEMBL506678 CHEMBL2304043	C011015	5 / 4 / 2	0 / 3	No. 520
C00002578	Tephrosin	CHEMBL241806	C480848		6 / 0	No. 589	No. 15
C00002522	Deguelin / (-)-cis-Deguelin	CHEMBL393417 CHEMBL1592086	C107676	12 / 20 / 45	86 / 10	No. 589	No. 15
C00030643	Lasiodiplodin	CHEMBL393258 CHEMBL1669748				No. 790

Human Protein / Gene in interactions

217 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000674 C00000960 C00001224 C00002522 C00002568 C00003672	0 / 1
P10636	Microtubule-associated protein tau	Unclassified protein	C00000674 C00000960 C00001232 C00002522 C00002568	4 / 3
P16473	Thyrotropin receptor	Glycohormone receptor	C00000674 C00001224 C00002522 C00002568 C00003672	3 / 2
P06746	DNA polymerase beta	Enzyme	C00000674 C00000960 C00002568 C00003672 C00019308	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00000674 C00000960 C00002522 C00002568 C00003672	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00000674 C00001224 C00001232 C00002522 C00002568	0 / 0
O75496	Geminin	Unclassified protein	C00000674 C00000960 C00001224 C00001232 C00002568	0 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000674 C00002522 C00002568 C00003672	1 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00000674 C00000960 C00001224 C00002568	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00000674 C00000960 C00001232 C00002522	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00000674 C00000960 C00001224 C00001232	0 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00000674 C00000960 C00002522 C00002568	7 / 37
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00000674 C00002522 C00002568 C00003672	0 / 1
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00000674 C00002522 C00002568 C00003672	1 / 1
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00000674 C00000960 C00001224 C00001232	3 / 3
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00000674 C00001224 C00002568 C00003672	1 / 1
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00000674 C00000960 C00001224 C00002568	2 / 2
P03372	Estrogen receptor	NR3A1	C00000674 C00001224 C00002568 C00003672	1 / 1
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00000674 C00001232 C00002568	0 / 0
P22303	Acetylcholinesterase	Hydrolase	C00000674 C00000960 C00002568	1 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00000674 C00000960 C00001224	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00000674 C00000960 C00002568	0 / 0
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00001224 C00001232 C00002568	5 / 3
O75164	Lysine-specific demethylase 4A	Enzyme	C00000674 C00000960 C00001232	0 / 0
P49841	Glycogen synthase kinase-3 beta	Gsk	C00000674 C00003672 C00019308	0 / 0
P10275	Androgen receptor	NR3C4	C00000674 C00001224 C00002568	3 / 4
Q16637	Survival motor neuron protein	Unclassified protein	C00000674 C00002522 C00002568	4 / 1
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00000674 C00001224 C00002568	0 / 0
P54132	Bloom syndrome protein	Enzyme	C00000674 C00001232 C00002568	1 / 2
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00000674 C00000960 C00002568	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00000674 C00000960 C00002568	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00000674 C00001224 C00002568	11 / 10
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00001224 C00002568	0 / 0
Q14191	Werner syndrome ATP-dependent helicase	Enzyme	C00000674 C00000960	2 / 1
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00000674 C00000960	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00000674 C00002568	0 / 0
P08047	Transcription factor Sp1	Unclassified protein	C00003672 C00019308	0 / 0
P05413	Fatty acid-binding protein, heart	Other cytosolic protein	C00001224 C00001232	0 / 0
P35610	Sterol O-acyltransferase 1	Enzyme	C00001224 C00001232	0 / 0
P10828	Thyroid hormone receptor beta	NR1A2	C00000674 C00002568	3 / 1
P19793	Retinoic acid receptor RXR-alpha	NR2B1	C00001224 C00002568	0 / 0
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00003672 C00019308	0 / 0
P06239	Tyrosine-protein kinase Lck	Src	C00000674 C00002568	0 / 1
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00000674 C00002568	1 / 1
Q07869	Peroxisome proliferator-activated receptor alpha	NR1C1	C00001224 C00001232	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00000674 C00002568	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00000674 C00002568	1 / 1
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00002568 C00003672	2 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00000674 C00002568	0 / 3
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00001232 C00002568	2 / 2
P15090	Fatty acid-binding protein, adipocyte	Other cytosolic protein	C00001224 C00001232	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00000960 C00002568	0 / 0
P04798	Cytochrome P450 1A1	Cytochrome P450 1A1	C00000674 C00000960	0 / 0
Q96RI1	Bile acid receptor	NR1H4	C00001224 C00001232	0 / 0
P08183	Multidrug resistance protein 1	drug	C00000674 C00003672	1 / 0
P13726	Tissue factor	Membrane receptor	C00001224 C00001232	0 / 0
Q16678	Cytochrome P450 1B1	Cytochrome P450 1B1	C00000674 C00000960	4 / 4
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00000674 C00000960	1 / 1
P14679	Tyrosinase	Oxidoreductase	C00000674 C00003672	4 / 2
P06493	Cyclin-dependent kinase 1	Cdc2	C00000674 C00002568	0 / 0
P11511	Cytochrome P450 19A1	Cytochrome P450 19A1	C00001224 C00001232	2 / 2
P04150	Glucocorticoid receptor	NR3C1	C00000674 C00002568	0 / 1
P00734	Prothrombin	S1A	C00003672 C00019308	4 / 2
P11021	78 kDa glucose-regulated protein	Unclassified protein	C00000674 C00000960	0 / 0
P14780	Matrix metalloproteinase-9	M10A	C00000674 C00002568	2 / 2
P83916	Chromobox protein homolog 1	Unclassified protein	C00001232 C00002568	0 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00000674 C00001232	1 / 2
Q9Y253	DNA polymerase eta	Enzyme	C00000674 C00000960	1 / 1
Q9UGP5	DNA polymerase lambda	Enzyme	C00001224 C00001232	0 / 0
P11387	DNA topoisomerase 1	Isomerase	C00000674 C00001232	0 / 0
P03956	Interstitial collagenase	M10A	C00000674 C00002568	0 / 1
P17252	Protein kinase C alpha type	Alpha	C00001232 C00002568	0 / 0
P04035	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oxidoreductase	C00001232 C00002568	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00001224 C00001232	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00000674 C00000960	0 / 0
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00000674 C00002568	0 / 0
P36888	Receptor-type tyrosine-protein kinase FLT3	Pdgfr	C00000674 C00000960	1 / 1
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00000674 C00000960	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00002568	0 / 0
P50052	Type-2 angiotensin II receptor	Angiotensin receptor	C00002568	1 / 1
P25929	Neuropeptide Y receptor type 1	Neuropeptide Y receptor	C00002568	0 / 0
P17948	Vascular endothelial growth factor receptor 1	Vegfr	C00002568	0 / 0
P41968	Melanocortin receptor 3	Melanocortin receptor	C00002568	1 / 0
P39900	Macrophage metalloelastase	M10A	C00000674	0 / 0
P29274	Adenosine receptor A2a	Adenosine receptor	C00002568	0 / 0
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00002568	0 / 0
Q9Y271	Cysteinyl leukotriene receptor 1	Leukotriene receptor	C00002568	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00002568	0 / 0
P37288	Vasopressin V1a receptor	Vasopressin and oxytocin receptor	C00002568	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00000674	2 / 0
P27361	Mitogen-activated protein kinase 3	Erk	C00002568	0 / 0
P51151	Ras-related protein Rab-9A	Unclassified protein	C00002568	0 / 0
P38398	Breast cancer type 1 susceptibility protein	Enzyme	C00000674	4 / 2
P23528	Cofilin-1	Unclassified protein	C00002568	0 / 0
P28907	ADP-ribosyl cyclase 1	Enzyme	C00000674	0 / 1
P08913	Alpha-2A adrenergic receptor	Adrenergic receptor	C00002568	0 / 0
P21917	D(4) dopamine receptor	Dopamine receptor	C00002568	0 / 0
P30988	Calcitonin receptor	Calcitonin receptor	C00002568	0 / 0
P35462	D(3) dopamine receptor	Dopamine receptor	C00002568	1 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00002568	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00002568	0 / 1
P41595	5-hydroxytryptamine receptor 2B	Serotonin receptor	C00002568	0 / 0
P25101	Endothelin-1 receptor	Endothelin receptor	C00002568	0 / 0
P30411	B2 bradykinin receptor	Bradykinin receptor	C00002568	0 / 0
P32245	Melanocortin receptor 4	Melanocortin receptor	C00002568	1 / 0
P14416	D(2) dopamine receptor	Dopamine receptor	C00002568	2 / 0
P32238	Cholecystokinin receptor type A	Cholecystokinin receptor	C00002568	0 / 0
P08311	Cathepsin G	S1A	C00002568	0 / 0
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00002568	1 / 0
O00519	Fatty-acid amide hydrolase 1	Enzyme	C00001232	0 / 0
P09874	Poly [ADP-ribose] polymerase 1	Enzyme	C00000674	0 / 0
P11388	DNA topoisomerase 2-alpha	Isomerase	C00000674	0 / 0
P32241	Vasoactive intestinal polypeptide receptor 1	Vasoactive intestinal peptide receptor	C00002568	0 / 0
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00002568	1 / 8
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00000674	1 / 0
P09923	Intestinal-type alkaline phosphatase	Enzyme	C00000960	0 / 0
P05186	Alkaline phosphatase, tissue-nonspecific isozyme	Enzyme	C00000960	3 / 1
Q9HC97	G-protein coupled receptor 35	Kynurenic acid receptor	C00000674	0 / 0
P51570	Galactokinase	Enzyme	C00000674	1 / 1
Q9HC16	DNA dC->dU-editing enzyme APOBEC-3G	Enzyme	C00002522	0 / 0
Q15078	Cyclin-dependent kinase 5 activator 1	REG serine/threonine protein kinase family	C00000674	0 / 0
P29466	Caspase-1	C14	C00002568	0 / 0
Q00535	Cyclin-dependent kinase 5	Cdk5	C00000674	0 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00000674	0 / 0
P08172	Muscarinic acetylcholine receptor M2	Acetylcholine receptor	C00002568	2 / 0
P11229	Muscarinic acetylcholine receptor M1	Acetylcholine receptor	C00002568	0 / 0
Q08209	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Ser_Thr	C00002568	0 / 0
P06241	Tyrosine-protein kinase Fyn	Src	C00002568	0 / 0
P21554	Cannabinoid receptor 1	Cannabinoid receptor	C00002568	0 / 0
P31645	Sodium-dependent serotonin transporter	Serotonin	C00002568	2 / 0
P24941	Cyclin-dependent kinase 2	Cdc2	C00000674	0 / 0
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00002568	5 / 9
P20309	Muscarinic acetylcholine receptor M3	Acetylcholine receptor	C00002568	1 / 0
P25024	C-X-C chemokine receptor type 1	CXC chemokine receptor	C00002568	0 / 0
P21452	Substance-K receptor	Neurokinin receptor	C00002568	0 / 0
P06276	Cholinesterase	Hydrolase	C00000674	0 / 0
P51679	C-C chemokine receptor type 4	CC chemokine receptor	C00002568	0 / 0
P51681	C-C chemokine receptor type 5	CC chemokine receptor	C00002568	3 / 0
P50406	5-hydroxytryptamine receptor 6	Serotonin receptor	C00002568	0 / 0
P06280	Alpha-galactosidase A	Enzyme	C00000674	1 / 1
P04745	Alpha-amylase 1	Enzyme	C00000674	0 / 0
P45452	Collagenase 3	M10A	C00000674	1 / 1
P49327	Fatty acid synthase	Transferase	C00000674	0 / 0
P18054	Arachidonate 12-lipoxygenase, 12S-type	Enzyme	C00000674	2 / 0
P51452	Dual specificity protein phosphatase 3	Ser_Thr_Tyr	C00001224	0 / 0
P35236	Tyrosine-protein phosphatase non-receptor type 7	Tyr	C00001224	0 / 0
P41597	C-C chemokine receptor type 2	CC chemokine receptor	C00002568	1 / 0
P11309	Serine/threonine-protein kinase pim-1	Pim	C00000674	0 / 0
P10696	Alkaline phosphatase, placental-like	Enzyme	C00000960	0 / 1
P08575	Receptor-type tyrosine-protein phosphatase C	Enzyme	C00002568	2 / 1
P04062	Glucosylceramidase	Enzyme	C00000674	6 / 4
P03905	NADH-ubiquinone oxidoreductase chain 4	Oxidoreductase	C00002568	3 / 1
P08253	72 kDa type IV collagenase	M10A	C00000674	1 / 3
Q01469	Fatty acid-binding protein, epidermal	Other cytosolic protein	C00001232	0 / 0
P49146	Neuropeptide Y receptor type 2	Neuropeptide Y receptor	C00002568	0 / 0
Q9UNQ0	ATP-binding cassette sub-family G member 2	ATP binding cassette	C00000674	2 / 0
P07148	Fatty acid-binding protein, liver	Unclassified protein	C00001232	0 / 0
Q92887	Canalicular multispecific organic anion transporter 1	Unclassified protein	C00002568	1 / 1
Q00534	Cyclin-dependent kinase 6	CMGC serine/threonine protein kinase family	C00000674	1 / 0
O15118	Niemann-Pick C1 protein	Unclassified protein	C00002568	1 / 1
Q01453	Peripheral myelin protein 22	Unclassified protein	C00002568	5 / 2
P51449	Nuclear receptor ROR-gamma	Nuclear hormone receptor subfamily 1 group F member 3	C00001232	0 / 0
Q16539	Mitogen-activated protein kinase 14	p38	C00002568	0 / 0
Q9H2K2	Tankyrase-2	Enzyme	C00000674	0 / 0
O14763	Tumor necrosis factor receptor superfamily member 10B	Unclassified protein	C00000674	1 / 0
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00002568	0 / 0
P33765	Adenosine receptor A3	Adenosine receptor	C00002568	0 / 0
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00002568	1 / 0
P08246	Neutrophil elastase	S1A	C00002568	2 / 1
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00002568	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00002568	0 / 0
Q9Y3R4	Sialidase-2	Enzyme	C00000674	0 / 0
P08173	Muscarinic acetylcholine receptor M4	Acetylcholine receptor	C00002568	0 / 0
P25103	Substance-P receptor	Neurokinin receptor	C00002568	0 / 0
P25105	Platelet-activating factor receptor	PAF receptor	C00002568	0 / 0
P33032	Melanocortin receptor 5	Melanocortin receptor	C00002568	0 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00002568	0 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00002568	0 / 0
P27338	Amine oxidase [flavin-containing] B	Oxidoreductase	C00000674	0 / 0
P05181	Cytochrome P450 2E1	Cytochrome P450 2E1	C00002568	0 / 0
O14842	Free fatty acid receptor 1	Free fatty acid receptor	C00001224	0 / 0
P21728	D(1A) dopamine receptor	Dopamine receptor	C00002568	0 / 0
Q15046	Lysine--tRNA ligase	Enzyme	C00000674	2 / 1
Q6W5P4	Neuropeptide S receptor	Neuropeptide receptor	C00002568	1 / 0
P14618	Pyruvate kinase PKM	Enzyme	C00000960	0 / 0
P08912	Muscarinic acetylcholine receptor M5	Acetylcholine receptor	C00002568	0 / 0
Q01959	Sodium-dependent dopamine transporter	Dopamine	C00002568	1 / 0
Q99549	M-phase phosphoprotein 8	Unclassified protein	C00002568	0 / 0
P35367	Histamine H1 receptor	Histamine receptor	C00002568	0 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00000674	0 / 0
P23975	Sodium-dependent noradrenaline transporter	Norepinephrine	C00002568	1 / 1
P25100	Alpha-1D adrenergic receptor	Adrenergic receptor	C00002568	0 / 0
P30542	Adenosine receptor A1	Adenosine receptor	C00002568	0 / 0
P25021	Histamine H2 receptor	Histamine receptor	C00002568	0 / 0
P18089	Alpha-2B adrenergic receptor	Adrenergic receptor	C00002568	0 / 0
P24557	Thromboxane-A synthase	Cytochrome P450 5A1	C00002568	1 / 1
P05412	Transcription factor AP-1	Transcription Factor	C00002568	0 / 0
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00002568	0 / 1
Q04760	Lactoylglutathione lyase	Enzyme	C00000674	0 / 0
P25025	C-X-C chemokine receptor type 2	CXC chemokine receptor	C00002568	0 / 0
P08254	Stromelysin-1	M10A	C00000674	1 / 0
P80365	Corticosteroid 11-beta-dehydrogenase isozyme 2	Enzyme	C00003672	1 / 1
Q9NPH5	NADPH oxidase 4	Enzyme	C00000674	0 / 0
P00918	Carbonic anhydrase 2	Lyase	C00002568	1 / 2
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00000674	1 / 1
P40225	Thrombopoietin	Unclassified protein	C00002568	1 / 1
Q13315	Serine-protein kinase ATM	Atypical serine/threonine protein kinase PIKK subfamily	C00001232	1 / 4
P42345	Serine/threonine-protein kinase mTOR	Enzyme	C00002568	0 / 0
O00255	Menin	Unclassified protein	C00000674	2 / 5
Q13951	Core-binding factor subunit beta	Unclassified protein	C00000674	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00000674	1 / 4
O95067	G2/mitotic-specific cyclin-B2	Other cytosolic protein	C00000674	0 / 0
P14635	G2/mitotic-specific cyclin-B1	Other cytosolic protein	C00000674	0 / 0
Q8WWL7	G2/mitotic-specific cyclin-B3	Other cytosolic protein	C00000674	0 / 0
P49840	Glycogen synthase kinase-3 alpha	Gsk	C00000674	0 / 0
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00002568	0 / 0
O95271	Tankyrase-1	Enzyme	C00000674	0 / 0

313 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00000674 C00001232 C00002522 C00002568 C00002578
4318	MMP9, CLG4B, GELB, MANDP2, MMP-9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35)	C00000674 C00002522 C00002578
4846	NOS3, ECNOS, eNOS	nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39)	C00001232 C00002522 C00002568
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00000674 C00002522 C00002568
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00001232 C00002522 C00002568
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00000674 C00002522 C00002578
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00000674 C00002522 C00002568
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00001232 C00002522 C00002568
7422	VEGFA, MVCD1, VEGF, VPF	vascular endothelial growth factor A	C00000674 C00002522 C00002568
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00000674 C00002522 C00002568
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00000674 C00002522 C00002568
847	CAT	catalase (EC:1.11.1.6)	C00000674 C00001232 C00002568
840	CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3	caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60)	C00000674 C00002522 C00002568
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00000674 C00002522 C00002568
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00000674 C00002568
672	BRCA1, BRCAI, BRCC1, BROVCA1, IRIS, PNCA4, PPP1R53, PSCP, RNF53	breast cancer 1, early onset	C00002522 C00002568
5599	MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c	mitogen-activated protein kinase 8 (EC:2.7.11.24)	C00000674 C00002568
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00002522 C00002568
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00000674 C00002568
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00000674 C00002568
2353	FOS, AP-1, C-FOS, p55	FBJ murine osteosarcoma viral oncogene homolog	C00000674 C00002568
598	BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS	BCL2-like 1	C00000674 C00002522
545	ATR, FCTCS, FRP1, MEC1, SCKL, SCKL1	ataxia telangiectasia and Rad3 related (EC:2.7.11.1)	C00002522 C00002568
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00000674 C00002568
581	BAX, BCL2L4	BCL2-associated X protein	C00000674 C00002568
330	BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2	baculoviral IAP repeat containing 3	C00002568 C00002578
329	BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1	baculoviral IAP repeat containing 2	C00000674 C00002578
331	XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3	X-linked inhibitor of apoptosis	C00000674 C00002522
472	ATM, AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1	ataxia telangiectasia mutated (EC:2.7.11.1)	C00002522 C00002568
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00002522 C00002568
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00000674 C00002522
4790	NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	C00000674 C00002568
6774	STAT3, APRF, HIES	signal transducer and activator of transcription 3 (acute-phase response factor)	C00002522 C00002568
6615	SNAI1, SLUGH2, SNA, SNAH, SNAIL, SNAIL1, dJ710H13.1	snail family zinc finger 1	C00002522 C00002568
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00000674 C00002522
5925	RB1, OSRC, RB, p105-Rb, pRb, pp110	retinoblastoma 1	C00001232 C00002522
6720	SREBF1, SREBP-1c, SREBP1, bHLHd1	sterol regulatory element binding transcription factor 1	C00001232 C00002568
5163	PDK1	pyruvate dehydrogenase kinase, isozyme 1 (EC:2.7.11.2)	C00002522 C00002568
29110	TBK1, NAK, T2K	TANK-binding kinase 1 (EC:2.7.11.1)	C00000674 C00000960
3091	HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	C00002522 C00002568
4780	NFE2L2, NRF2	nuclear factor, erythroid 2-like 2	C00000960 C00002568
3479	IGF1, IGF-I, IGF1A, IGFI	insulin-like growth factor 1 (somatomedin C)	C00002522 C00002568
4953	ODC1, ODC	ornithine decarboxylase 1 (EC:4.1.1.17)	C00002522 C00002568
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00000960 C00002568
4792	NFKBIA, IKBA, MAD-3, NFKBI	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	C00000674 C00002522
9429	ABCG2, ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR1, UAQTL1	ATP-binding cassette, sub-family G (WHITE), member 2	C00000674 C00001232
4363	ABCC1, ABC29, ABCC, GS-X, MRP, MRP1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	C00000674 C00000960
1017	CDK2, p33(CDK2)	cyclin-dependent kinase 2 (EC:2.7.11.22)	C00000674
5604	MAP2K1, CFC3, MAPKK1, MEK1, MKK1, PRKMK1	mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)	C00002522
5605	MAP2K2, CFC4, MAPKK2, MEK2, MKK2, PRKMK2	mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)	C00002522
4170	MCL1, BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT	myeloid cell leukemia sequence 1 (BCL2-related)	C00002522
4255	MGMT	O-6-methylguanine-DNA methyltransferase (EC:2.1.1.63)	C00002522
4288	MKI67, KIA, MIB-1	marker of proliferation Ki-67	C00002522
3791	KDR, CD309, FLK1, VEGFR, VEGFR2	kinase insert domain receptor (a type III receptor tyrosine kinase) (EC:2.7.10.1)	C00002522
2475	MTOR, FRAP, FRAP1, FRAP2, RAFT1, RAPT1	mechanistic target of rapamycin (serine/threonine kinase) (EC:2.7.11.1)	C00002522
4609	MYC, MRTL, MYCC, bHLHe39, c-Myc	v-myc avian myelocytomatosis viral oncogene homolog	C00002522
8202	NCOA3, ACTR, AIB-1, AIB1, CAGH16, CTG26, KAT13B, RAC3, SRC-3, SRC3, TNRC14, TNRC16, TRAM-1, bHLHe42, pCIP	nuclear receptor coactivator 3 (EC:2.3.1.48)	C00002522
3586	IL10, CSIF, GVHDS, IL-10, IL10A, TGIF	interleukin 10	C00002522
3549	IHH, BDA1, HHG2	indian hedgehog	C00002522
4928	NUP98, ADIR2, NUP196, NUP96	nucleoporin 98kDa	C00002522
3480	IGF1R, CD221, IGFIR, IGFR, JTK13	insulin-like growth factor 1 receptor (EC:2.7.10.1)	C00002522
2932	GSK3B	glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26)	C00002522
8325	FZD8, FZ-8, hFZ8	frizzled family receptor 8	C00002522
5290	PIK3CA, CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, p110-alpha	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha (EC:2.7.11.1 2.7.1.153)	C00002522
5591	PRKDC, DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350	protein kinase, DNA-activated, catalytic polypeptide (EC:2.7.11.1)	C00002522
8322	FZD4, CD344, EVR1, FEVR, FZD4S, Fz-4, Fz4, FzE4, GPCR, hFz4	frizzled family receptor 4	C00002522
11211	FZD10, CD350, FZ-10, Fz10, FzE7, hFz10	frizzled family receptor 10	C00002522
2487	FRZB, FRE, FRITZ, FRP-3, FRZB-1, FRZB-PEN, FRZB1, FZRB, OS1, SFRP3, SRFP3, hFIZ	frizzled-related protein	C00002522
6194	RPS6, S6	ribosomal protein S6	C00002522
6198	RPS6KB1, PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70_S6KA, p70(S6K)-alpha, p70-S6K, p70-alpha	ribosomal protein S6 kinase, 70kDa, polypeptide 1 (EC:2.7.11.1)	C00002522
6423	SFRP2, FRP-2, SARP1, SDF-5	secreted frizzled-related protein 2	C00002522
2034	EPAS1, ECYT4, HIF2A, HLF, MOP2, PASD2, bHLHe73	endothelial PAS domain protein 1	C00002522
8403	SOX14, SOX28	SRY (sex determining region Y)-box 14	C00002522
11063	SOX30	SRY (sex determining region Y)-box 30	C00002522
6660	SOX5, L-SOX5	SRY (sex determining region Y)-box 5	C00002522
6714	SRC, ASV, SRC1, c-SRC, p60-Src	v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (EC:2.7.10.2)	C00002522
1978	EIF4EBP1, 4E-BP1, 4EBP1, BP-1, PHAS-I	eukaryotic translation initiation factor 4E binding protein 1	C00002522
6778	STAT6, D12S1644, IL-4-STAT, STAT6B, STAT6C	signal transducer and activator of transcription 6, interleukin-4 induced	C00002522
412	STS, ARSC, ARSC1, ASC, ES, SSDD, XLI	steroid sulfatase (microsomal), isozyme S (EC:3.1.6.2)	C00002522
6925	TCF4, E2-2, ITF-2, ITF2, PTHS, SEF-2, SEF2, SEF2-1, SEF2-1A, SEF2-1B, TCF-4, bHLHb19	transcription factor 4	C00002522
112399	EGLN3, HIFP4H3, HIFPH3, PHD3	egl-9 family hypoxia-inducible factor 3 (EC:1.14.11.29)	C00002522
27121	DKK4, DKK-4	dickkopf WNT signaling pathway inhibitor 4	C00002522
27123	DKK2, DKK-2	dickkopf WNT signaling pathway inhibitor 2	C00002522
11197	WIF1, WIF-1	WNT inhibitory factor 1	C00002522
80326	WNT10A, OODD, SSPS, STHAG4	wingless-type MMTV integration site family, member 10A	C00002522
7481	WNT11, HWNT11	wingless-type MMTV integration site family, member 11	C00002522
7222233			C00002522
7472	WNT2, INT1L1, IRP	wingless-type MMTV integration site family member 2	C00002522
7482	WNT2B, WNT13, XWNT2	wingless-type MMTV integration site family, member 2B	C00002522
89780	WNT3A	wingless-type MMTV integration site family, member 3A	C00002522
7852	CXCR4, CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM	chemokine (C-X-C motif) receptor 4	C00002522
1499	CTNNB1, CTNNB, MRD19, armadillo	catenin (cadherin-associated protein), beta 1, 88kDa	C00002522
7122	CLDN5, AWAL, BEC1, CPETRL1, TMVCF	claudin 5	C00002522
4843	NOS2, HEP-NOS, INOS, NOS, NOS2A	nitric oxide synthase 2, inducible (EC:1.14.13.39)	C00002578
5243	ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1	ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44)	C00002568
28976	ACAD9, NPD002	acyl-CoA dehydrogenase family, member 9	C00002568
48	ACO1, ACONS, IREB1, IREBP, IREBP1, IRP1	aconitase 1, soluble (EC:4.2.1.3)	C00002568
50	ACO2, ACONM, ICRD	aconitase 2, mitochondrial (EC:4.2.1.3)	C00002568
54	ACP5, SPENCDI, TRAP	acid phosphatase 5, tartrate resistant (EC:3.1.3.2)	C00002568
59	ACTA2, AAT6, ACTSA, MYMY5	actin, alpha 2, smooth muscle, aorta	C00002568
183	AGT, ANHU, SERPINA8	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	C00002568
9131	AIFM1, AIF, CMTX4, COWCK, COXPD6, PDCD8	apoptosis-inducing factor, mitochondrion-associated, 1	C00002568
290	ANPEP, APN, CD13, GP150, LAP1, P150, PEPN	alanyl (membrane) aminopeptidase (EC:3.4.11.2)	C00002568
317	APAF1, APAF-1, CED4	apoptotic peptidase activating factor 1	C00002568
402	ARL2, ARFL2	ADP-ribosylation factor-like 2	C00002568
468	ATF4, CREB-2, CREB2, TAXREB67, TXREB	activating transcription factor 4	C00002568
9474	ATG5, APG5, APG5-LIKE, APG5L, ASP, hAPG5	autophagy related 5	C00002568
514	ATP5E, ATPE, MC5DN3	ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit (EC:3.6.3.14)	C00002568
518	ATP5G3, P3	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)	C00002568
521	ATP5I, ATP5K	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E (EC:3.6.1.14)	C00002568
522	ATP5J, ATP5, ATP5A, ATPM, CF6, F6	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 (EC:3.6.1.14)	C00002568
10632	ATP5L, ATP5JG	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G (EC:3.6.1.14)	C00002568
539	ATP5O, ATPO, OSCP	ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (EC:3.6.3.14)	C00002568
4287	ATXN3, AT3, ATX3, JOS, MJD, MJD1, SCA3	ataxin 3 (EC:3.4.19.12)	C00002568
23621	BACE1, ASP2, BACE, HSPC104	beta-site APP-cleaving enzyme 1 (EC:3.4.23.46)	C00002568
572	BAD, BBC2, BCL2L8	BCL2-associated agonist of cell death	C00002568
580	BARD1	BRCA1 associated RING domain 1	C00002568
9075	CLDN2	claudin 2	C00002522
8678	BECN1, ATG6, VPS30, beclin1	beclin 1, autophagy related	C00002568
675	BRCA2, BRCC2, BROVCA2, FACD, FAD, FAD1, FANCB, FANCD, FANCD1, GLM3, PNCA2	breast cancer 2, early onset	C00002568
701	BUB1B, BUB1beta, BUBR1, Bub1A, MAD3L, MVA1, SSK1, hBUBR1	BUB1 mitotic checkpoint serine/threonine kinase B (EC:2.7.11.1)	C00002568
8837	CFLAR, CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS	CASP8 and FADD-like apoptosis regulator	C00002522
1019	CDK4, CMM3, PSK-J3	cyclin-dependent kinase 4 (EC:2.7.11.22)	C00002522
902	CCNH, CAK, p34, p37	cyclin H	C00002568
929	CD14	CD14 molecule	C00002568
948	CD36, BDPLT10, CHDS7, FAT, GP3B, GP4, GPIV, PASIV, SCARB3	CD36 molecule (thrombospondin receptor)	C00002568
952	CD38, T10	CD38 molecule (EC:3.2.2.5)	C00002568
999	CDH1, Arc-1, CD324, CDHE, ECAD, LCAM, UVO	cadherin 1, type 1, E-cadherin (epithelial)	C00002568
1111	CHEK1, CHK1	checkpoint kinase 1 (EC:2.7.11.1)	C00002568
29883	CNOT7, CAF1, Caf1a, hCAF-1	CCR4-NOT transcription complex, subunit 7 (EC:3.1.13.4)	C00002568
1270	CNTF, HCNTF	ciliary neurotrophic factor	C00002568
1293	COL6A3	collagen, type VI, alpha 3	C00002568
1327	COX4I1, COX4, COX4-1, COXIV	cytochrome c oxidase subunit IV isoform 1 (EC:1.9.3.1)	C00002568
9377	COX5A, COX, COX-VA, VA	cytochrome c oxidase subunit Va (EC:1.9.3.1)	C00002568
1329	COX5B, COXVB	cytochrome c oxidase subunit Vb (EC:1.9.3.1)	C00002568
1347	COX7A2, COX7AL, COX7AL1, COXVIIAL, COXVIIa-L, VIIAL	cytochrome c oxidase subunit VIIa polypeptide 2 (liver) (EC:1.9.3.1)	C00002568
1349	COX7B, APLCC	cytochrome c oxidase subunit VIIb (EC:1.9.3.1)	C00002568
1356	CP, CP-2	ceruloplasmin (ferroxidase) (EC:1.16.3.1)	C00002568
1588	CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM	cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00002568
1649	DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153	DNA-damage-inducible transcript 3	C00002568
1677	DFFB, CAD, CPAN, DFF-40, DFF2, DFF40	DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)	C00002568
10072	DPP3, DPPIII	dipeptidyl-peptidase 3 (EC:3.4.14.4)	C00002568
9451	EIF2AK3, PEK, PERK, WRS	eukaryotic translation initiation factor 2-alpha kinase 3 (EC:2.7.11.1)	C00002568
1965	EIF2S1, EIF-2, EIF-2A, EIF-2alpha, EIF2, EIF2A	eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa	C00002568
9156	EXO1, HEX1, hExoI	exonuclease 1	C00002568
2175	FANCA, FA, FA-H, FA1, FAA, FACA, FAH, FANCH	Fanconi anemia, complementation group A	C00002568
2176	FANCC, FA3, FAC, FACC	Fanconi anemia, complementation group C	C00002568
2177	FANCD2, FA-D2, FA4, FACD, FAD, FAD2, FANCD	Fanconi anemia, complementation group D2	C00002568
2178	FANCE, FACE, FAE	Fanconi anemia, complementation group E	C00002568
2188	FANCF, FAF	Fanconi anemia, complementation group F	C00002568
2189	FANCG, FAG, XRCC9	Fanconi anemia, complementation group G	C00002568
355	FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6	Fas cell surface death receptor	C00002568
2335	FN1, CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF	fibronectin 1	C00002568
1007	CDH9	cadherin 9, type 2 (T1-cadherin)	C00002522
2495	FTH1, FHC, FTH, FTHL6, PIG15, PLIF	ferritin, heavy polypeptide 1 (EC:1.16.3.1)	C00002568
2876	GPX1, GPXD, GSHPX1	glutathione peroxidase 1 (EC:1.11.1.9)	C00002568
10456	HAX1, HCLSBP1, HS1BP1, SCN3	HCLS1 associated protein X-1	C00002568
3313	HSPA9, CSA, GRP-75, GRP75, HSPA9B, MOT, MOT2, MTHSP75, PBP74	heat shock 70kDa protein 9 (mortalin)	C00002568
27429	HTRA2, OMI, PARK13, PRSS25	HtrA serine peptidase 2 (EC:3.4.21.108)	C00002568
3364	HUS1, hHUS1	HUS1 checkpoint homolog (S. pombe)	C00002568
3419	IDH3A	isocitrate dehydrogenase 3 (NAD+) alpha (EC:1.1.1.41)	C00002568
3458	IFNG, IFG, IFI	interferon, gamma	C00002568
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00002568
3716	JAK1, JAK1A, JAK1B, JTK3	Janus kinase 1 (EC:2.7.10.2)	C00002568
3717	JAK2, JTK10, THCYT3	Janus kinase 2 (EC:2.7.10.2)	C00002568
1005	CDH7, CDH7L1	cadherin 7, type 2	C00002522
3952	LEP, LEPD, OB, OBS	leptin	C00002568
120892	LRRK2, AURA17, DARDARIN, PARK8, RIPK7, ROCO2	leucine-rich repeat kinase 2 (EC:2.7.11.1)	C00002568
1001	CDH3, CDHP, HJMD, PCAD	cadherin 3, type 1, P-cadherin (placental)	C00002522
1432	MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA	mitogen-activated protein kinase 14 (EC:2.7.11.24)	C00002568
768	CA9, CAIX, MN	carbonic anhydrase IX (EC:4.2.1.1)	C00002522
332	BIRC5, API4, EPR-1	baculoviral IAP repeat containing 5	C00002522
4137	MAPT, DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, TAU	microtubule-associated protein tau	C00002568
4313	MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24)	C00002568
4361	MRE11A, ATLD, HNGS1, MRE11, MRE11B	MRE11 meiotic recombination 11 homolog A (S. cerevisiae)	C00002568
64965	MRPS9, MRP-S9, RPMS9, S9mt	mitochondrial ribosomal protein S9	C00002568
4481	MSR1, CD204, SCARA1, SR-A, SRA, phSR1, phSR2	macrophage scavenger receptor 1	C00002568
4490	MT1B, MT1, MT1Q, MTP	metallothionein 1B	C00002568
4502	MT2A, MT2	metallothionein 2A	C00002568
80198	MUS81, SLX3	MUS81 structure-specific endonuclease subunit (EC:3.1.22.-)	C00002568
10135	NAMPT, 1110035O14Rik, PBEF, PBEF1, VF, VISFATIN	nicotinamide phosphoribosyltransferase (EC:2.4.2.12)	C00002568
4541	ND6, MTND6, MT-ND6	NADH dehydrogenase, subunit 6 (complex I)	C00002568
4705	NDUFA10, CI-42KD, CI-42k	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa (EC:1.6.5.3 1.6.99.3)	C00002568
4696	NDUFA3, B9, CI-B9	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa	C00002568
4697	NDUFA4, CI-9k, CI-MLRQ, MLRQ	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa (EC:1.6.5.3 1.6.99.3)	C00002568
4700	NDUFA6, B14, CI-B14, LYRM6, NADHB14	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa	C00002568
4704	NDUFA9, CC6, CI-39k, CI39k, NDUFS2L, SDR22E1	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa	C00002568
4707	NDUFB1, CI-MNLL, CI-SGDH, MNLL	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa	C00002568
4708	NDUFB2, AGGG, CI-AGGG	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa (EC:1.6.5.3 1.6.99.3)	C00002568
4709	NDUFB3, B12, CI-B12	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa	C00002568
4710	NDUFB4, B15, CI-B15	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa (EC:1.6.5.3 1.6.99.3)	C00002568
4711	NDUFB5, CISGDH, SGDH	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa (EC:1.6.5.3 1.6.99.3)	C00002568
4712	NDUFB6, B17, CI	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa (EC:1.6.5.3 1.6.99.3)	C00002568
4713	NDUFB7, B18, CI-B18	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa (EC:1.6.5.3 1.6.99.3)	C00002568
4714	NDUFB8, ASHI, CI-ASHI	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa	C00002568
4724	NDUFS4, AQDQ, CI-18	NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)	C00002568
4726	NDUFS6, CI-13kA, CI-13kD-A, CI13KDA	NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) (EC:1.6.5.3 1.6.99.3)	C00002568
4728	NDUFS8, CI-23k, CI23KD, TYKY	NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) (EC:1.6.5.3 1.6.99.3)	C00002568
10725	NFAT5, NF-AT5, NFATL1, NFATZ, OREBP, TONEBP	nuclear factor of activated T-cells 5, tonicity-responsive	C00002568
4772	NFATC1, NF-ATC, NFAT2, NFATc	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	C00002568
51129	ANGPTL4, ANGPTL2, ARP4, FIAF, HARP, HFARP, NL2, PGAR, UNQ171, pp1158	angiopoietin-like 4	C00002522
4879	NPPB, BNP	natriuretic peptide B	C00002568
4521	NUDT1, MTH1	nudix (nucleoside diphosphate linked moiety X)-type motif 1 (EC:3.6.1.55 3.6.1.56)	C00002568
4976	OPA1, MGM1, NPG, NTG, largeG	optic atrophy 1 (autosomal dominant) (EC:3.6.5.5)	C00002568
126014	OSCAR, PIGR3, PIgR-3	osteoclast associated, immunoglobulin-like receptor	C00002568
5071	PARK2, AR-JP, LPRS2, PDJ, PRKN	parkin RBR E3 ubiquitin protein ligase	C00002568
11315	PARK7, DJ-1, DJ1	parkinson protein 7	C00002568
5162	PDHB, PDHBD, PDHE1-B, PHE1B	pyruvate dehydrogenase (lipoamide) beta (EC:1.2.4.1)	C00002568
65018	PINK1, BRPK, PARK6	PTEN induced putative kinase 1 (EC:2.7.11.1)	C00002568
5422	POLA1, POLA, p180	polymerase (DNA directed), alpha 1, catalytic subunit (EC:2.7.7.7)	C00002568
5427	POLE2, DPE2	polymerase (DNA directed), epsilon 2, accessory subunit (EC:2.7.7.7)	C00002568
5481	PPID, CYP-40, CYPD	peptidylprolyl isomerase D (EC:5.2.1.8)	C00002568
5562	PRKAA1, AMPK, AMPKa1	protein kinase, AMP-activated, alpha 1 catalytic subunit (EC:2.7.11.1 2.7.11.26 2.7.11.27 2.7.11.31)	C00002568
8842	PROM1, AC133, CD133, CORD12, MCDR2, PROML1, RP41, STGD4	prominin 1	C00002568
5810	RAD1, HRAD1, REC1	RAD1 homolog (S. pombe) (EC:3.1.11.2)	C00002568
5884	RAD17, CCYC, HRAD17, R24L, RAD17SP, RAD24	RAD17 homolog (S. pombe)	C00002568
56852	RAD18, RNF73	RAD18 homolog (S. cerevisiae)	C00002568
10111	RAD50, NBSLD, RAD502, hRad50	RAD50 homolog (S. cerevisiae)	C00002568
5888	RAD51, BRCC5, HRAD51, HsRad51, HsT16930, MRMV2, RAD51A, RECA	RAD51 recombinase	C00002568
10635	RAD51AP1, PIR51	RAD51 associated protein 1	C00002568
25788	RAD54B, RDH54	RAD54 homolog B (S. cerevisiae)	C00002568
5883	RAD9A, RAD9	RAD9 homolog A (S. pombe) (EC:3.1.11.2)	C00002568
5984	RFC4, A1, RFC37	replication factor C (activator 1) 4, 37kDa	C00002568
5985	RFC5, RFC36	replication factor C (activator 1) 5, 36.5kDa	C00002568
6513	SLC2A1, DYT17, DYT18, DYT9, EIG12, GLUT, GLUT1, GLUT1DS, HTLVR, PED	solute carrier family 2 (facilitated glucose transporter), member 1	C00002568
6539	SLC6A12, BGT-1, BGT1, GAT2	solute carrier family 6 (neurotransmitter transporter), member 12	C00002568
6531	SLC6A3, DAT, DAT1, PKDYS	solute carrier family 6 (neurotransmitter transporter), member 3	C00002568
6606	SMN1, BCD541, GEMIN1, SMA, SMA1, SMA2, SMA3, SMA4, SMA@, SMN, SMNT, T-BCD541, TDRD16A	survival of motor neuron 1, telomeric	C00002568
6622	SNCA, NACP, PARK1, PARK4, PD1	synuclein, alpha (non A4 component of amyloid precursor)	C00002568
6648	SOD2, IPOB, MNSOD, MVCD6	superoxide dismutase 2, mitochondrial (EC:1.15.1.1)	C00002568
8878	SQSTM1, A170, OSIL, PDB3, ZIP3, p60, p62, p62B	sequestosome 1	C00002568
133	ADM, AM	adrenomedullin	C00002522
6742	SSBP1, Mt-SSB, SOSS-B1, SSBP, mtSSB	single-stranded DNA binding protein 1, mitochondrial	C00002568
6772	STAT1, CANDF7, ISGF-3, STAT91	signal transducer and activator of transcription 1, 91kDa	C00002568
7084	TK2, MTDPS2, MTTK	thymidine kinase 2, mitochondrial (EC:2.7.1.21)	C00002568
4982	TNFRSF11B, OCIF, OPG, TR1	tumor necrosis factor receptor superfamily, member 11b	C00002568
8600	TNFSF11, CD254, ODF, OPGL, OPTB2, RANKL, TRANCE, hRANKL2, sOdf	tumor necrosis factor (ligand) superfamily, member 11	C00002568
25828	TXN2, MT-TRX, MTRX, TRX2	thioredoxin 2	C00002568
7334	UBE2N, UBC13, UbcH-ben, UbcH13	ubiquitin-conjugating enzyme E2N (EC:6.3.2.19)	C00002568
7381	UQCRB, MC3DN3, QCR7, QP-C, QPC, UQBC, UQBP, UQCR6, UQPC	ubiquinol-cytochrome c reductase binding protein (EC:1.10.2.2)	C00002568
7384	UQCRC1, D3S3191, QCR1, UQCR1	ubiquinol-cytochrome c reductase core protein I (EC:1.10.2.2)	C00002568
7416	VDAC1, PORIN, VDAC-1	voltage-dependent anion channel 1	C00002568
7421	VDR, NR1I1	vitamin D (1,25- dihydroxyvitamin D3) receptor	C00002568
7498	XDH, XO, XOR	xanthine dehydrogenase (EC:1.17.1.4 1.17.3.2)	C00002568
7529	YWHAB, GW128, HS1, KCIP-1, YWHAA	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	C00002568
7532	YWHAG, 14-3-3GAMMA	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	C00002568
19	ABCA1, ABC-1, ABC1, CERP, HDLDT1, TGD	ATP-binding cassette, sub-family A (ABC1), member 1	C00001232
9619	ABCG1, ABC8, WHITE1	ATP-binding cassette, sub-family G (WHITE), member 1	C00001232
2950	GSTP1, DFN7, FAEES3, GST3, GSTP, PI	glutathione S-transferase pi 1 (EC:2.5.1.18)	C00000960
213	ALB, PRO0883, PRO0903, PRO1341	albumin	C00001232
335	APOA1	apolipoprotein A-I	C00001232
338	APOB, FLDB, LDLCQ4	apolipoprotein B	C00001232
1401	CRP, PTX1	C-reactive protein, pentraxin-related	C00001232
1869	E2F1, E2F-1, RBAP1, RBBP3, RBP3	E2F transcription factor 1	C00001232
1906	EDN1, ET1, HDLCQ7, PPET1	endothelin 1	C00001232
3630	INS, IDDM2, ILPR, IRDN, MODY10	insulin	C00001232
5444	PON1, ESA, MVCD5, PON	paraoxonase 1 (EC:3.1.1.2 3.1.8.1 3.1.1.81)	C00001232
778733			C00001232
5465	PPARA, NR1C1, PPAR, PPARalpha, hPPAR	peroxisome proliferator-activated receptor alpha	C00001232
100136658			C00001232
5467	PPARD, FAAR, NR1C2, NUC1, NUCI, NUCII, PPARB	peroxisome proliferator-activated receptor delta	C00001232
5468	PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma	peroxisome proliferator-activated receptor gamma	C00001232
6256	RXRA, NR2B1	retinoid X receptor, alpha	C00001232
5054	SERPINE1, PAI, PAI-1, PAI1, PLANH1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	C00001232
6514	SLC2A2, GLUT2	solute carrier family 2 (facilitated glucose transporter), member 2	C00001232
177	AGER, RAGE	advanced glycosylation end product-specific receptor	C00000674
196	AHR, bHLHe76	aryl hydrocarbon receptor	C00000674
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00000674
890	CCNA2, CCN1, CCNA	cyclin A2	C00000674
891	CCNB1, CCNB	cyclin B1	C00000674
958	CD40, Bp50, CDW40, TNFRSF5, p50	CD40 molecule, TNF receptor superfamily member 5	C00000674
972	CD74, DHLAG, HLADG, II, Ia-GAMMA	CD74 molecule, major histocompatibility complex, class II invariant chain	C00000674
983	CDK1, CDC2, CDC28A, P34CDC2	cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22)	C00000674
4015	LOX	lysyl oxidase (EC:1.4.3.13)	C00002522
1027	CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	C00000674
1031	CDKN2C, INK4C, p18, p18-INK4C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	C00000674
1437	CSF2, GMCSF	colony stimulating factor 2 (granulocyte-macrophage)	C00000674
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00000674
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00000674
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00000674
1577	CYP3A5, CP35, CYPIIIA5, P450PCN3, PCN3	cytochrome P450, family 3, subfamily A, polypeptide 5 (EC:1.14.14.1)	C00000674
1950	EGF, HOMG4, URG	epidermal growth factor	C00000674
1958	EGR1, AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225	early growth response 1	C00000674
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00000674
2100	ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2	estrogen receptor 2 (ER beta)	C00000674
2203	FBP1, FBP	fructose-1,6-bisphosphatase 1 (EC:3.1.3.11)	C00000674
2354	FOSB, AP-1, G0S3, GOS3, GOSB	FBJ murine osteosarcoma viral oncogene homolog B	C00000674
4616	GADD45B, GADD45BETA, MYD118	growth arrest and DNA-damage-inducible, beta	C00000674
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00000674
3565	IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4	interleukin 4	C00000674
3726	JUNB, AP-1	jun B proto-oncogene	C00000674
3727	JUND, AP-1	jun D proto-oncogene	C00000674
5602	MAPK10, JNK3, JNK3A, PRKM10, SAPK1b, p493F12, p54bSAPK	mitogen-activated protein kinase 10 (EC:2.7.11.24)	C00000674
5601	MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK	mitogen-activated protein kinase 9 (EC:2.7.11.24)	C00000674
4312	MMP1, CLG, CLGN	matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7)	C00000674
4793	NFKBIB, IKBB, TRIP9	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	C00000674
9572	NR1D1, EAR1, THRA1, THRAL, ear-1, hRev	nuclear receptor subfamily 1, group D, member 1	C00000674
5347	PLK1, PLK, STPK13	polo-like kinase 1 (EC:2.7.11.21)	C00000674
8000	PSCA, PRO232	prostate stem cell antigen	C00000674
5747	PTK2, FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK	protein tyrosine kinase 2 (EC:2.7.10.2)	C00000674
6401	SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2	selectin E	C00000674
2810	SFN, YWHAS	stratifin	C00000674
6647	SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer	superoxide dismutase 1, soluble (EC:1.15.1.1)	C00000674
7128	TNFAIP3, A20, OTUD7C, TNFA1P2	tumor necrosis factor, alpha-induced protein 3 (EC:3.4.19.12)	C00000674
8743	TNFSF10, APO2L, Apo-2L, CD253, TL2, TRAIL	tumor necrosis factor (ligand) superfamily, member 10	C00000674
9540	TP53I3, PIG3	tumor protein p53 inducible protein 3	C00000674
8626	TP63, AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L	tumor protein p63	C00000674
7161	TP73, P73	tumor protein p73	C00000674
54658	UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A	UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17)	C00000674
54659	UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C	UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17)	C00000674
10451	VAV3	vav 3 guanine nucleotide exchange factor	C00000674
7412	VCAM1, CD106, INCAM-100	vascular cell adhesion molecule 1	C00000674
8839	WISP2, CCN5, CT58, CTGF-L	WNT1 inducible signaling pathway protein 2	C00000674

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