| Organism name | Erythrina abyssinica |
|---|---|
| Genus | Erythrina |
| Family | Fabaceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Erythrina abyssinica |
|---|---|
| Linked NCBI taxonomy ID | 1237573 |
| Linked level | species |
| Family in NCBI taxonomy | Fabaceae |
|---|---|
| ID | 3803 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | rosids |
|---|---|
| ID | 71275 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00038344
|
Abyssinoflavanone VII
|
CHEMBL229220
|
1 / 0 / 0 | No. 19 | No. 14 |
|
||
|
C00000936
|
Abyssinone V
|
CHEMBL255890
CHEMBL454332 |
C056679
|
2 / 0 / 0 | No. 19 | No. 14 |
|
|
|
C00014176
|
Abyssinin III
/ Abyssinoflavanone III / 5,7,3',4'-Tetrahydroxy-5',6'-diprenylflavanone |
No. 19 | No. 14 |
|
||||
|
C00014175
|
Abyssinone V 4'-methyl ether
/ 5,7-Dihydroxy-4'-methoxy-3',5'-diprenylflavanone |
CHEMBL470249
CHEMBL1425525 |
20 / 20 / 13 | No. 19 | No. 14 |
|
||
|
C00008202
|
Abyssinone IV
|
CHEMBL470454
|
1 / 0 / 0 | No. 19 | No. 14 |
|
||
|
C00008319
|
Sigmoidin A
|
CHEMBL229506
|
C064221
|
1 / 0 / 0 | No. 19 | No. 14 |
|
|
|
C00001869
|
Isoboldine
/ (S)-Isoboldine |
CHEMBL462880
|
19 / 22 / 55 | No. 20 | No. 4 |
|
||
|
C00000996
|
Abyssinin II
/ Abyssinoflavanone II / 5'-Prenylhomoeriodictyol |
CHEMBL388722
|
1 / 0 / 0 | No. 28 | No. 14 |
|
||
|
C00014213
|
Abyssinoflavanone IV
/ 5,7,3'-Trihydroxy-2'-prenyl-[2'',3'':4',5']furanoflavanone |
No. 28 | No. 14 |
|
||||
|
C00008201
|
Abyssinone II
|
CHEMBL389924
CHEMBL558103 CHEMBL1688178 |
2 / 2 / 2 | No. 28 | No. 14 |
|
||
|
C00008318
|
Sigmoidin B
|
CHEMBL229454
|
C064222
|
1 / 0 / 0 | No. 28 | No. 14 |
|
|
|
C00008203
|
Abyssinone III
|
CHEMBL454077
CHEMBL1688179 CHEMBL1688180 |
1 / 0 / 0 | No. 39 |
|
|||
|
C00008465
|
Sigmoidin F
|
CHEMBL229222
|
C062901
|
1 / 0 / 0 | No. 39 |
|
||
|
C00008320
|
Sigmoidin C
|
CHEMBL229617
|
1 / 0 / 0 | No. 127 | No. 14 |
|
||
|
C00014240
|
Abyssinin I
/ Abyssinoflavanone I / (2S)-5,7-Dihydroxy-3'-methoxy-6'',6''-dimethylpyrano[2'',3'':4',5']flavanone |
CHEMBL389736
|
1 / 0 / 0 | No. 127 | No. 14 |
|
||
|
C00014456
|
Licoagrochalcone A
/ 3-Prenyl-4,2',4'-trihydroxychalcone |
CHEMBL229885
|
2 / 2 / 2 | No. 133 | No. 13 |
|
||
|
C00035796
|
5-Prenylbutein
|
CHEMBL253677
|
No. 133 | No. 13 |
|
|||
|
C00002559
|
Phaseolin
/ (-)-Phaseollin |
CHEMBL448350
|
No. 135 | No. 15 |
|
|||
|
C00002371
|
Abyssinone VI
|
CHEMBL508727
|
1 / 0 / 0 | No. 190 | No. 13 |
|
||
|
C00014257
|
Abyssinoflavanone V
/ 5,7,3'-Trihydroxy-2'-prenyl-(5''-hydroxy-6'',6''-dimethyldihydropyrano[2'',3'':4',5'])flavanone |
No. 235 |
|
|||||
|
C00001852
|
Erythratidine
|
No. 273 | No. 4 |
|
||||
|
C00002515
|
Cristacarpin
/ Erythrabyssin I |
CHEMBL454849
|
C085157
|
2 / 1 / 1 | No. 325 | No. 15 |
|
|
|
C00001851
|
Erysotrine
|
CHEMBL442947
|
No. 446 | No. 4 |
|
|||
|
C00009669
|
Erythrabyssin II
/ 3,9-Dihydroxy-2,10-diprenylpterocarpan |
CHEMBL455372
|
1 / 0 / 0 | No. 460 |
|
|||
|
C00008457
|
Sigmoidin D
|
CHEMBL516331
|
C051738
|
1 / 0 / 0 | No. 740 |
|
||
|
C00014261
|
Abyssinoflavanone VI
/ 5,7-Dihydroxy-(5''-hydroxy-6'',6''-dimethylpyrano[2'',3'':7,6])-6''',6'''-dimethyldihydropyrano[2''',3''':4',3']flavanone |
No. 2013 |
|
|||||
|
C00000935
|
Abyssinone I
|
No. 8287 | No. 14 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00000936 C00000996 C00002371 C00008201 C00008202 C00008203 C00008318 C00008319 C00008320 C00008457 C00008465 C00009669 C00014175 C00014240 C00014456 C00038344 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00001869 C00014175 | 4 / 3 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001869 C00014175 | 0 / 0 |
| P11511 | Cytochrome P450 19A1 | Cytochrome P450 19A1 | C00008201 C00014456 | 2 / 2 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00001869 C00014175 | 1 / 2 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00001869 | 2 / 2 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00014175 | 0 / 0 |
| Q13315 | Serine-protein kinase ATM | Atypical serine/threonine protein kinase PIKK subfamily | C00014175 | 1 / 4 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00001869 | 0 / 1 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00001869 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00014175 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00014175 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00014175 | 2 / 0 |
| O75496 | Geminin | Unclassified protein | C00014175 | 0 / 0 |
| Q92731 | Estrogen receptor beta | NR3A2 | C00002515 | 0 / 1 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00014175 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00014175 | 7 / 3 |
| Q99700 | Ataxin-2 | Unclassified protein | C00014175 | 1 / 1 |
| P17861 | X-box-binding protein 1 | Unclassified protein | C00014175 | 1 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00001869 | 3 / 3 |
| P29466 | Caspase-1 | C14 | C00001869 | 0 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00014175 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00002515 | 1 / 1 |
| P55210 | Caspase-7 | C14 | C00001869 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001869 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001869 | 0 / 1 |
| Q6W5P4 | Neuropeptide S receptor | Neuropeptide receptor | C00014175 | 1 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00014175 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00001869 | 0 / 0 |
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00001869 | 7 / 37 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00014175 | 0 / 0 |
| P04054 | Phospholipase A2 | Enzyme | C00000936 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00001869 | 0 / 0 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001869 | 1 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00001869 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00014175 | 1 / 0 |
| O00255 | Menin | Unclassified protein | C00001869 | 2 / 5 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00001869 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00001869 | 1 / 4 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00014175 | 1 / 1 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #613546 | Aromatase deficiency |
P11511
|
| #139300 | Aromatase excess syndrome; aexs |
P11511
|
| #608584 | Asthma-related traits, susceptibility to, 2 |
Q6W5P4
|
| #208900 | Ataxia-telangiectasia; at |
Q13315
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #133239 | Esophageal cancer |
P04637
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #211980 | Lung cancer |
P04637
|
| #612371 | Major affective disorder 7; mafd7 |
P17861
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04637 (related) Q92731 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
Q01196 (related) |
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
Q13315 (related) |
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00016 | Oral cancer |
P04637
(related)
P04637 (marker) |
| H00017 | Esophageal cancer |
P04637
(related)
P04637 (marker) |
| H00018 | Gastric cancer |
P04637
(related)
|
| H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00022 | Bladder cancer |
P04637
(related)
|
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) |
| H00027 | Ovarian cancer |
P04637
(related)
|
| H00028 | Choriocarcinoma |
P04637
(related)
|
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00031 | Breast cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
|
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
|
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00042 | Glioma |
P04637
(related)
P04637 (marker) |
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00046 | Cholangiocarcinoma |
P04637
(related)
|
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00055 | Laryngeal cancer |
P04637
(related)
P04637 (marker) |
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00021 | Renal cell carcinoma |
P04637
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P11511
(related)
|
| H00794 | Aromatase excess syndrome |
P11511
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00064 | Ataxia telangiectasia (AT) |
Q13315
(related)
|
| H00094 | DNA repair defects |
Q13315
(related)
|
| H00848 | Ataxia with ocular apraxia (AOA) |
Q13315
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|