Markhamia stipulata
Species
KNApSAcK Entry
| Organism name | Markhamia stipulata |
|---|---|
| Genus | Markhamia |
| Family | Bignoniaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Markhamia |
|---|---|
| Linked NCBI taxonomy ID | 211921 |
| Linked level | genus |
Family
| Family in NCBI taxonomy | Bignoniaceae |
|---|---|
| ID | 24079 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Metabolite list (24)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00036501
|
O-Apiosylverbascoside
/ 2''-O-beta-Apiosylverbascoside |
No. 33 |
|
|||||
|
C00002783
|
Kusaginin
/ Acteoside / Verbascoside |
CHEMBL231853
CHEMBL444478 CHEMBL1364101 |
C058956
|
12 / 1 / 1 | 34 / 3 | No. 33 |
|
|
|
C00037480
|
Markhamioside E
/ (-)-Markhamioside E |
No. 33 |
|
|||||
|
C00037479
|
Markhamioside D
/ (-)-Markhamioside D |
No. 33 |
|
|||||
|
C00037477
|
Markhamioside B
/ (-)-Markhamioside B |
No. 33 |
|
|||||
|
C00030695
|
Luteoside B
/ Newbouldioside |
CHEMBL450497
|
No. 33 |
|
||||
|
C00037478
|
Markhamioside C
/ (+)-Markhamioside C |
No. 33 |
|
|||||
|
C00030516
|
Isoacteoside
/ Isoverbascoside |
CHEMBL504873
|
C064683
|
6 / 5 / 4 | No. 33 |
|
||
|
C00037442
|
Luteoside A
/ (-)-Luteoside A |
CHEMBL511027
|
No. 33 |
|
||||
|
C00003672
|
Sitosterol
/ beta-sitosterl / (-)-beta-Sitosterol / Stigmast-5-en-3beta-ol |
CHEMBL221542
CHEMBL1398443 CHEMBL1875388 |
17 / 19 / 12 | No. 53 | No. 11 |
|
||
|
C00010600
|
Ajugol
/ Leonuride |
CHEMBL595516
|
No. 64 | No. 36 |
|
|||
|
C00001253
|
Palmitone
/ Hentriacontan-16-one |
No. 115 |
|
|||||
|
C00030098
|
Verbasoside
/ (-)-Verbasoside / Decaffeoylverbascoside / (-)-Decaffeoylverbascoside |
CHEMBL1779146
|
No. 128 | No. 72 |
|
|||
|
C00036313
|
(+)-Lyoniresinol 3alpha-O-beta-glucopyranoside
/ (+)-Lyoniresinol 3alpha-O-beta-D-glucopyranoside |
CHEMBL464198
CHEMBL1159486 CHEMBL1159487 CHEMBL1813178 CHEMBL1813179 CHEMBL1813180 CHEMBL1813181 CHEMBL2332109 |
6 / 11 / 5 | No. 174 | No. 22 |
|
||
|
C00031467
|
(6R,9R)-Roseoside
/ (-)-(6R,9R)-Roseoside |
CHEMBL444196
CHEMBL482383 CHEMBL520291 CHEMBL465921 |
No. 225 |
|
||||
|
C00037481
|
Markhamioside F
/ (-)-Markhamioside F |
No. 267 |
|
|||||
|
C00037372
|
Khaephuoside B
/ (-)-Khaephuoside B |
No. 411 |
|
|||||
|
C00037601
|
Paulownin
/ (+)-Paulownin |
CHEMBL479911
|
C008773
|
No. 621 | No. 21 |
|
||
|
C00037896
|
Tectol
|
CHEMBL461704
|
C053744
|
No. 2127 |
|
|||
|
C00037011
|
Dehydro-alpha-lapachone
|
CHEMBL272253
|
C029244
|
1 / 0 / 0 | No. 2274 |
|
||
|
C00030741
|
Markhamioside A
/ (-)-Markhamioside A |
No. 2799 |
|
|||||
|
C00002836
|
beta-Lapachone
|
CHEMBL15192
|
C014638
|
53 / 61 / 77 | 5 / 1 | No. 3485 |
|
|
|
C00002835
|
Lapachol
|
CHEMBL15193
|
C008252
|
13 / 20 / 50 | No. 4183 | No. 80 |
|
|
|
C00037726
|
Rengyoside B
|
No. 7815 |
|
Human Protein / Gene in interactions
81 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00002783 C00002836 C00036313 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00002835 C00002836 C00003672 | 0 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00002783 C00002836 | 0 / 0 |
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00002835 C00002836 | 7 / 37 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00002835 C00002836 | 4 / 1 |
| O00255 | Menin | Unclassified protein | C00002835 C00002836 | 2 / 5 |
| Q99700 | Ataxin-2 | Unclassified protein | C00002783 C00002836 | 1 / 1 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00002836 C00003672 | 2 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00002836 C00003672 | 1 / 1 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00002836 C00003672 | 1 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00002835 C00002836 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00002835 C00002836 | 4 / 3 |
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00003672 C00036313 | 0 / 0 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00002835 C00002836 | 1 / 2 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00002836 C00036313 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00002836 C00003672 | 1 / 1 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00002836 C00003672 | 0 / 0 |
| P00734 | Prothrombin | S1A | C00003672 C00036313 | 4 / 2 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00002835 C00002836 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00002783 C00002836 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00002783 C00002836 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00002836 C00003672 | 0 / 1 |
| P39748 | Flap endonuclease 1 | Enzyme | C00002783 C00002836 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00002835 C00002836 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00002835 C00002836 | 2 / 3 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00002836 | 1 / 1 |
| P11388 | DNA topoisomerase 2-alpha | Isomerase | C00002836 | 0 / 0 |
| Q9HC97 | G-protein coupled receptor 35 | Kynurenic acid receptor | C00002835 | 0 / 0 |
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00002836 | 0 / 0 |
| P51570 | Galactokinase | Enzyme | C00002836 | 1 / 1 |
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00002836 | 0 / 0 |
| P14902 | Indoleamine 2,3-dioxygenase 1 | Enzyme | C00037011 | 0 / 0 |
| P54132 | Bloom syndrome protein | Enzyme | C00002836 | 1 / 2 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00002836 | 2 / 0 |
| P08183 | Multidrug resistance protein 1 | drug | C00003672 | 1 / 0 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00002836 | 0 / 0 |
| P49841 | Glycogen synthase kinase-3 beta | Gsk | C00003672 | 0 / 0 |
| O00519 | Fatty-acid amide hydrolase 1 | Enzyme | C00002836 | 0 / 0 |
| P03956 | Interstitial collagenase | M10A | C00030516 | 0 / 1 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00036313 | 7 / 3 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00002836 | 1 / 0 |
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00002783 | 0 / 0 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00002836 | 3 / 1 |
| P11021 | 78 kDa glucose-regulated protein | Unclassified protein | C00002836 | 0 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00003672 | 3 / 2 |
| Q9P0U3 | Sentrin-specific protease 1 | Enzyme | C00036313 | 0 / 0 |
| P37840 | Alpha-synuclein | Unclassified protein | C00002836 | 4 / 2 |
| P14679 | Tyrosinase | Oxidoreductase | C00003672 | 4 / 2 |
| P06280 | Alpha-galactosidase A | Enzyme | C00002836 | 1 / 1 |
| P45452 | Collagenase 3 | M10A | C00030516 | 1 / 1 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00002836 | 0 / 0 |
| P08047 | Transcription factor Sp1 | Unclassified protein | C00003672 | 0 / 0 |
| P08253 | 72 kDa type IV collagenase | M10A | C00030516 | 1 / 3 |
| Q01453 | Peripheral myelin protein 22 | Unclassified protein | C00002836 | 5 / 2 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00002836 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00003672 | 1 / 1 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00002836 | 0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00002836 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00002836 | 11 / 10 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00030516 | 2 / 2 |
| P39900 | Macrophage metalloelastase | M10A | C00030516 | 0 / 0 |
| Q6W5P4 | Neuropeptide S receptor | Neuropeptide receptor | C00002836 | 1 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00002783 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00002835 | 0 / 0 |
| P17252 | Protein kinase C alpha type | Alpha | C00002783 | 0 / 0 |
| Q99549 | M-phase phosphoprotein 8 | Unclassified protein | C00002836 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00002836 | 0 / 0 |
| Q04760 | Lactoylglutathione lyase | Enzyme | C00002835 | 0 / 0 |
| P08254 | Stromelysin-1 | M10A | C00030516 | 1 / 0 |
| P80365 | Corticosteroid 11-beta-dehydrogenase isozyme 2 | Enzyme | C00003672 | 1 / 1 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00002783 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00003672 | 0 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00002836 | 0 / 0 |
| P40225 | Thrombopoietin | Unclassified protein | C00002836 | 1 / 1 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00002836 | 2 / 2 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00002836 | 0 / 0 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00002783 | 0 / 0 |
| P42345 | Serine/threonine-protein kinase mTOR | Enzyme | C00002836 | 0 / 0 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00002836 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00002836 | 1 / 4 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00002783 | 0 / 0 |
38 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00002783
C00002836
|
| 1869 | E2F1, E2F-1, RBAP1, RBBP3, RBP3 | E2F transcription factor 1 |
C00002783
|
| 2950 | GSTP1, DFN7, FAEES3, GST3, GSTP, PI | glutathione S-transferase pi 1 (EC:2.5.1.18) |
C00002836
|
| 81631 | MAP1LC3B, ATG8F, LC3B, MAP1A/1BLC3, MAP1LC3B-a | microtubule-associated protein 1 light chain 3 beta |
C00002836
|
| 10533 | ATG7, APG7-LIKE, APG7L, GSA7 | autophagy related 7 |
C00002836
|
| 196 | AHR, bHLHe76 | aryl hydrocarbon receptor |
C00002783
|
| 405 | ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2 | aryl hydrocarbon receptor nuclear translocator |
C00002783
|
| 6347 | CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF | chemokine (C-C motif) ligand 2 |
C00002783
|
| 595 | CCND1, BCL1, D11S287E, PRAD1, U21B31 | cyclin D1 |
C00002783
|
| 894 | CCND2, KIAK0002 | cyclin D2 |
C00002783
|
| 896 | CCND3 | cyclin D3 |
C00002783
|
| 898 | CCNE1, CCNE | cyclin E1 |
C00002783
|
| 1017 | CDK2, p33(CDK2) | cyclin-dependent kinase 2 (EC:2.7.11.22) |
C00002783
|
| 1019 | CDK4, CMM3, PSK-J3 | cyclin-dependent kinase 4 (EC:2.7.11.22) |
C00002783
|
| 1021 | CDK6, PLSTIRE | cyclin-dependent kinase 6 (EC:2.7.11.22) |
C00002783
|
| 1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
C00002783
|
| 1027 | CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1 | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
C00002783
|
| 3627 | CXCL10, C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1 | chemokine (C-X-C motif) ligand 10 |
C00002783
|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00002783
|
| 8678 | BECN1, ATG6, VPS30, beclin1 | beclin 1, autophagy related |
C00002836
|
| 1956 | EGFR, ERBB, ERBB1, HER1, PIG61, mENA | epidermal growth factor receptor (EC:2.7.10.1) |
C00002783
|
| 3383 | ICAM1, BB2, CD54, P3.58 | intercellular adhesion molecule 1 |
C00002783
|
| 3458 | IFNG, IFG, IFI | interferon, gamma |
C00002783
|
| 3569 | IL6, BSF2, HGF, HSF, IFNB2, IL-6 | interleukin 6 (interferon, beta 2) |
C00002783
|
| 3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00002783
|
| 3689 | ITGB2, CD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
C00002783
|
| 5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00002783
|
| 5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00002783
|
| 27035 | NOX1, GP91-2, MOX1, NOH-1, NOH1 | NADPH oxidase 1 |
C00002783
|
| 5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00002783
|
| 5925 | RB1, OSRC, RB, p105-Rb, pRb, pp110 | retinoblastoma 1 |
C00002783
|
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00002783
|
| 4087 | SMAD2, JV18, JV18-1, MADH2, MADR2, hMAD-2, hSMAD2 | SMAD family member 2 |
C00002783
|
| 4088 | SMAD3, HSPC193, HsT17436, JV15-2, LDS1C, LDS3, MADH3 | SMAD family member 3 |
C00002783
|
| 6648 | SOD2, IPOB, MNSOD, MVCD6 | superoxide dismutase 2, mitochondrial (EC:1.15.1.1) |
C00002783
|
| 7039 | TGFA, TFGA | transforming growth factor, alpha |
C00002783
|
| 7040 | TGFB1, CED, DPD1, LAP, TGFB, TGFbeta | transforming growth factor, beta 1 |
C00002783
|
| 7412 | VCAM1, CD106, INCAM-100 | vascular cell adhesion molecule 1 |
C00002783
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (87)
| OMIM | preferred title | UniProt |
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
| #203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
| #606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
| #218030 | Apparent mineralocorticoid excess; ame |
P80365
|
| #608584 | Asthma-related traits, susceptibility to, 2 |
Q6W5P4
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #210900 | Bloom syndrome; blm |
P54132
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #118300 | Charcot-marie-tooth disease and deafness |
Q01453
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #118220 | Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a |
Q01453
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #614466 | Coronary heart disease, susceptibility to, 6; chds6 |
P08254
|
| #127750 | Dementia, lewy body; dlb |
P37840
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #133239 | Esophageal cancer |
P04637
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #301500 | Fabry disease |
P06280
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #230200 | Galactokinase deficiency |
P51570
|
| #139393 | Guillain-barre syndrome, familial; gbs |
Q01453
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #145900 | Hypertrophic neuropathy of dejerine-sottas |
Q01453
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P04637
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #259600 | Multicentric osteolysis, nodulosis, and arthropathy; mona |
P08253
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #162500 | Neuropathy, hereditary, with liability to pressure palsies; hnpp |
Q01453
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
| #605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
| #168600 | Parkinson disease, late-onset; pd |
P37840
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #614390 | Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 |
P00734
|
| #613679 | Prothrombin deficiency, congenital |
P00734
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #602111 | Spondyloepimetaphyseal dysplasia, missouri type |
P45452
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| #601367 | Stroke, ischemic |
P00734
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #187950 | Thrombocythemia 1; thcyt1 |
P40225
|
| #188050 | Thrombophilia due to thrombin defect; thph1 |
P00734
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
KEGG DISEASE (88)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00223 | Inherited thrombophilia |
P00734
(related)
|
| H01254 | Congenital prothrombin deficiency |
P00734
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
Q01453 (related) |
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04637 (related) |
| H00028 | Choriocarcinoma |
P03956
(related)
P04637 (related) P08253 (related) |
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
Q01196 (related) |
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00016 | Oral cancer |
P04637
(related)
P04637 (marker) |
| H00017 | Esophageal cancer |
P04637
(related)
P04637 (marker) |
| H00018 | Gastric cancer |
P04637
(related)
|
| H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00022 | Bladder cancer |
P04637
(related)
|
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) P08253 (related) P14780 (related) |
| H00027 | Ovarian cancer |
P04637
(related)
|
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00031 | Breast cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
|
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
P14679 (marker) |
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00042 | Glioma |
P04637
(related)
P04637 (marker) |
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00046 | Cholangiocarcinoma |
P04637
(related)
|
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00055 | Laryngeal cancer |
P04637
(related)
P04637 (marker) |
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00021 | Renal cell carcinoma |
P04637
(marker)
|
| H00125 | Fabry disease |
P06280
(related)
|
| H00472 | Torg-Winchester syndrome |
P08253
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
| H00479 | Metaphyseal dysplasias |
P14780
(related)
P45452 (related) |
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00057 | Parkinson's disease (PD) |
P37840
(related)
|
| H00066 | Lewy body dementia (LBD) |
P37840
(related)
|
| H00227 | Congenital amegakaryocytic thrombocytopenia (CAMT) |
P40225
(marker)
|
| H00070 | Galactosemia |
P51570
(related)
|
| H00094 | DNA repair defects |
P54132
(related)
|
| H00296 | Defects in RecQ helicases |
P54132
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00259 | Apparent mineralocorticoid excess syndrome |
P80365
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H01296 | Hereditary neuropathy with liability to pressure palsies (HNPP) |
Q01453
(related)
|
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
Q9NUW8 (related) |
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|