Aspergillus terreus

• Index
• Plant Species
• Metabolite list (34)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Aspergillus terreus
Genus	Aspergillus
Family	Trichocomaceae
Kingdom	Fungi

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Aspergillus terreus
Linked NCBI taxonomy ID	33178
Linked level	species

Family

Family in NCBI taxonomy	Aspergillaceae
ID	1131492

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Fungi
ID	4751

Plant class

Plant class
ID

Metabolite list (34)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00019420	Physcion / 1,8-Dihydroxy-3-methyl-6-methoxyanthraquinone	CHEMBL42624	C008905	18 / 20 / 14	1 / 0	No. 41	No. 62
C00036300	(+)-Aristolochene	CHEMBL484228				No. 151	No. 38
C00036278	(-)-gamma-Cadinene					No. 283	No. 39
C00043071	Territrem B	CHEMBL24686	C040405	2 / 2 / 1		No. 573
C00043070	Territrem A	CHEMBL470039	C040404	2 / 1 / 1		No. 573
C00044554	Asterriquinone C-1	CHEMBL467829				No. 614
C00044555	Asterriquinone D	CHEMBL512621				No. 614
C00026700	Terrequinone A	CHEMBL485268				No. 614
C00027038	Asterriquinone B1					No. 614
C00016018	Dehydrocurvularin / Dehydro-curvularin / trans-Dehydrocurvularin / alpha,beta-Dehydrocurvularin	CHEMBL482050 CHEMBL520014 CHEMBL1643635	C013914	21 / 19 / 20		No. 871
C00043149	11-Hydroxycurvularin	CHEMBL520015 CHEMBL516578 CHEMBL476690				No. 1108
C00018332	Dihydromevinolin	CHEMBL54712 CHEMBL76114	C031351			No. 1556
C00048322	Aspernolide B / (+)-Aspernolide B					No. 1559
C00048321	Aspernolide A / (+)-Aspernolide A					No. 1559
C00043311	Betulinan A	CHEMBL467203		1 / 0 / 0		No. 1626
C00023813	Terretonin	CHEMBL511953		9 / 2 / 2		No. 1901
C00043068	Terretonin C / (-)-Terretonin C					No. 1901
C00043066	Terretonin A / (-)-Terretonin A	CHEMBL470042		2 / 1 / 1		No. 1901
C00001392	L-Selenocystathionine					No. 2039
C00021842	8-Hydroxyquadrone	CHEMBL477718				No. 2669
C00021840	Isoquadrone					No. 2669
C00021841	6-Hydroxyisoquadrone					No. 2669
C00021843	Terrecyclol					No. 3115
C00048554	Terrein	CHEMBL238189 CHEMBL1981317				No. 3550
C00042249	Asterrelenin / (+)-Asterrelenin					No. 3596
C00043067	Terretonin B / (+)-Terretonin B					No. 4492
C00043069	Terretonin D / (-)-Terretonin D					No. 4492
C00032305	Terreusinone / (+)-Terreusinone					No. 5687
C00032304	Terreusinol / (+)-Terreusinol					No. 5687
C00044396	(+)-5(6)-Dihydro-6-hydroxyterrecyclic acid A	CHEMBL467404				No. 5731
C00043970	Terrefuranone	CHEMBL519366				No. 5999
C00026784	Asterredione / (-)-Asterredione	CHEMBL467403				No. 6506
C00024000	Mycoin / Patulin / Clavitin / Tercinin / Leucopin / Clavicin / Expansion / Penicidin / Claviformin / 4-Hydroxy-4H-furo[3,2-c]pyran-2(6H)-one	CHEMBL294018	D010365	21 / 26 / 48	23 / 2	No. 7818
C00021378	Aspterric acid		C465302			No. 8586

Human Protein / Gene in interactions

55 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
O43451	Maltase-glucoamylase, intestinal	Hydrolase	C00019420 C00023813 C00043066 C00043070	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00016018 C00019420 C00024000	2 / 3
Q9UBT6	DNA polymerase kappa	Enzyme	C00016018 C00019420 C00024000	0 / 0
P14410	Sucrase-isomaltase, intestinal	Enzyme	C00023813 C00043066 C00043070	1 / 1
P10636	Microtubule-associated protein tau	Unclassified protein	C00016018 C00019420 C00024000	4 / 3
P03372	Estrogen receptor	NR3A1	C00019420 C00024000	1 / 1
Q9UNA4	DNA polymerase iota	Enzyme	C00016018 C00023813	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00023813 C00024000	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00016018 C00023813	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00019420 C00024000	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00016018 C00023813	1 / 1
P00352	Retinal dehydrogenase 1	Enzyme	C00019420 C00024000	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00016018 C00023813	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00016018 C00023813	0 / 0
P51151	Ras-related protein Rab-9A	Unclassified protein	C00016018 C00023813	0 / 0
Q9H244	P2Y purinoceptor 12	Purine receptor	C00019420	1 / 1
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00016018	2 / 0
P23528	Cofilin-1	Unclassified protein	C00024000	0 / 0
P08311	Cathepsin G	S1A	C00019420	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00016018	0 / 0
P24752	Acetyl-CoA acetyltransferase, mitochondrial	Enzyme	C00043071	1 / 1
Q07343	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	PDE_4B	C00043311	0 / 0
Q9HC16	DNA dC->dU-editing enzyme APOBEC-3G	Enzyme	C00016018	0 / 0
P11021	78 kDa glucose-regulated protein	Unclassified protein	C00024000	0 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00024000	7 / 37
P04150	Glucocorticoid receptor	NR3C1	C00024000	0 / 1
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00024000	5 / 3
O75496	Geminin	Unclassified protein	C00016018	0 / 0
P06280	Alpha-galactosidase A	Enzyme	C00019420	1 / 1
Q96RI1	Bile acid receptor	NR1H4	C00024000	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00024000	0 / 0
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00019420	2 / 2
O15118	Niemann-Pick C1 protein	Unclassified protein	C00016018	1 / 1
O75030	Microphthalmia-associated transcription factor	Unclassified protein	C00016018	4 / 4
P06493	Cyclin-dependent kinase 1	Cdc2	C00024000	0 / 0
P19793	Retinoic acid receptor RXR-alpha	NR2B1	C00024000	0 / 0
P22303	Acetylcholinesterase	Hydrolase	C00043071	1 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00019420	0 / 0
P10828	Thyroid hormone receptor beta	NR1A2	C00024000	3 / 1
Q6W5P4	Neuropeptide S receptor	Neuropeptide receptor	C00016018	1 / 0
Q13315	Serine-protein kinase ATM	Atypical serine/threonine protein kinase PIKK subfamily	C00016018	1 / 4
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00024000	0 / 0
P08246	Neutrophil elastase	S1A	C00019420	2 / 1
Q99700	Ataxin-2	Unclassified protein	C00016018	1 / 1
P05412	Transcription factor AP-1	Transcription Factor	C00024000	0 / 0
P06239	Tyrosine-protein kinase Lck	Src	C00019420	0 / 1
P35869	Aryl hydrocarbon receptor	Transcription Factor	C00024000	0 / 0
Q16637	Survival motor neuron protein	Unclassified protein	C00024000	4 / 1
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00019420	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00016018	1 / 0
Q92731	Estrogen receptor beta	NR3A2	C00019420	0 / 1
P09619	Platelet-derived growth factor receptor beta	Pdgfr	C00019420	5 / 1
P16234	Platelet-derived growth factor receptor alpha	Pdgfr	C00019420	2 / 1
P01215	Glycoprotein hormones alpha chain	Unclassified protein	C00016018	0 / 3
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00016018	1 / 1

24 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
581	BAX, BCL2L4	BCL2-associated X protein	C00019420
467	ATF3	activating transcription factor 3	C00024000
10018	BCL2L11, BAM, BIM, BOD	BCL2-like 11 (apoptosis facilitator)	C00024000
637	BID, FP497	BH3 interacting domain death agonist	C00024000
847	CAT	catalase (EC:1.11.1.6)	C00024000
9076	CLDN1, CLD1, ILVASC, SEMP1	claudin 1	C00024000
1365	CLDN3, C7orf1, CPE-R2, CPETR2, HRVP1, RVP1	claudin 3	C00024000
1364	CLDN4, CPE-R, CPER, CPETR, CPETR1, WBSCR8, hCPE-R	claudin 4	C00024000
1649	DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153	DNA-damage-inducible transcript 3	C00024000
3458	IFNG, IFG, IFI	interferon, gamma	C00024000
3586	IL10, CSIF, GVHDS, IL-10, IL10A, TGIF	interleukin 10	C00024000
3596	IL13, IL-13, P600	interleukin 13	C00024000
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00024000
3565	IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4	interleukin 4	C00024000
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00024000
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00024000
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00024000
100506658	OCLN, BLCPMG	occludin (EC:2.1.1.67)	C00024000
5366	PMAIP1, APR, NOXA	phorbol-12-myristate-13-acetate-induced protein 1	C00024000
23645	PPP1R15A, GADD34	protein phosphatase 1, regulatory subunit 15A	C00024000
6647	SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer	superoxide dismutase 1, soluble (EC:1.15.1.1)	C00024000
7082	TJP1, ZO-1	tight junction protein 1	C00024000
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00024000
7494	XBP1, TREB5, XBP-1, XBP2	X-box binding protein 1	C00024000

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions