Papaver setigerum
Species
KNApSAcK Entry
| Organism name | Papaver setigerum |
|---|---|
| Genus | Papaver |
| Family | Papaveraceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Papaver somniferum subsp. setigerum |
|---|---|
| Linked NCBI taxonomy ID | 215229 |
| Linked level | subspecies |
Family
| Family in NCBI taxonomy | Papaveraceae |
|---|---|
| ID | 3465 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | eudicotyledons |
|---|---|
| ID | 71240 |
Metabolite list (16)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00025655
|
Corytuberine
/ (+)-Corytuberine |
CHEMBL227965
|
C013896
|
1 / 0 / 0 | No. 20 | No. 4 |
|
|
|
C00001869
|
Isoboldine
/ (S)-Isoboldine |
CHEMBL462880
|
19 / 22 / 55 | No. 20 | No. 4 |
|
||
|
C00026092
|
Scoulerine
/ (-)-Scoulerine |
CHEMBL191133
CHEMBL1235966 CHEMBL1395394 |
27 / 19 / 15 | No. 37 | No. 4 |
|
||
|
C00026095
|
Stylopine
/ (-)-Stylopine / l-Tetrahydrocoptisine / (-)-Tetrahydrocoptisine |
CHEMBL1922602
|
No. 37 | No. 4 |
|
|||
|
C00024668
|
YHL II
/ Coptisine |
CHEMBL362071
|
C034384
|
No. 155 | No. 4 |
|
||
|
C00001885
|
Escholin
/ Escholine / Thalictrin / Thalictrine / Magnoflorine / (+)-Magnoflorine |
CHEMBL235428
|
C001670
|
No. 286 | No. 4 |
|
||
|
C00025457
|
Papaverrubin A
/ Papaverrubine A / N-Demethylisorheadine |
No. 305 |
|
|||||
|
C00025459
|
Papaverrubine C
/ Epiporphyroxine / 14-Epiporphyroxine |
No. 305 |
|
|||||
|
C00001876
|
Laudanosine
/ L-Laudanosine / O-Methylcodamine / L-(+)-Laudanosine |
CHEMBL1407
CHEMBL519894 CHEMBL1613 |
C001522
|
18 / 26 / 21 | 0 / 1 | No. 345 | No. 4 |
|
|
C00027591
|
Setigeridine
|
No. 1165 | No. 4 |
|
||||
|
C00027467
|
Papavarine
|
CHEMBL19224
|
121 / 66 / 52 | No. 1165 | No. 4 |
|
||
|
C00027592
|
Setigerine
|
No. 1165 | No. 4 |
|
||||
|
C00001924
|
Thebaine
/ (-)-Thebaine / Paramorphine |
CHEMBL403893
CHEMBL1318110 |
D013797
|
4 / 0 / 0 | No. 1983 | No. 4 |
|
|
|
C00027573
|
N-Methylthebaine iodide
/ (-)-N-Methylthebaine iodide |
No. 1983 | No. 4 |
|
||||
|
C00001889
|
Morphine
/ (-)-Morphine |
CHEMBL70
CHEMBL1888905 CHEMBL2133708 CHEMBL2139208 |
D009020
|
32 / 17 / 11 | 71 / 199 | No. 4235 | No. 4 |
|
|
C00001837
|
Codeine
/ (-)-Codeine |
CHEMBL485
CHEMBL22662 CHEMBL612012 CHEMBL1907378 |
D003061
|
16 / 12 / 6 | 6 / 66 | No. 4235 | No. 4 |
|
Human Protein / Gene in interactions
163 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001837 C00001869 C00001876 C00001889 C00026092 C00027467 | 1 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00001869 C00001876 C00001889 C00026092 C00027467 | 0 / 1 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001869 C00001876 C00001889 C00026092 C00027467 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001869 C00001876 C00001889 C00026092 C00027467 | 0 / 1 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001876 C00001889 C00026092 C00027467 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00001876 C00001889 C00001924 C00026092 | 0 / 0 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00001837 C00001889 C00001924 C00027467 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001869 C00001876 C00026092 | 0 / 0 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00001837 C00001889 C00027467 | 2 / 2 |
| Q9NY46 | Sodium channel protein type 3 subunit alpha | SCN alpha, NaV1.x | C00001837 C00001889 C00027467 | 0 / 0 |
| Q99250 | Sodium channel protein type 2 subunit alpha | SCN alpha, NaV1.x | C00001837 C00001889 C00027467 | 2 / 2 |
| P02545 | Prelamin-A/C | Unclassified protein | C00001876 C00026092 C00027467 | 11 / 10 |
| P41143 | Delta-type opioid receptor | Opioid receptor | C00001837 C00001889 C00027467 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00001889 C00001924 C00026092 | 0 / 0 |
| P29466 | Caspase-1 | C14 | C00001869 C00026092 C00027467 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00001869 C00001876 C00027467 | 0 / 0 |
| P41145 | Kappa-type opioid receptor | Opioid receptor | C00001837 C00001889 C00027467 | 0 / 0 |
| P35498 | Sodium channel protein type 1 subunit alpha | SCN alpha, NaV1.x | C00001837 C00001889 C00027467 | 3 / 2 |
| O15245 | Solute carrier family 22 member 1 | Drug uniporter | C00001837 C00001889 C00027467 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00001876 C00001889 C00027467 | 0 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00001876 C00001889 | 0 / 0 |
| P22310 | UDP-glucuronosyltransferase 1-4 | Enzyme | C00001837 C00001889 | 3 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00026092 C00027467 | 0 / 0 |
| Q9HAW8 | UDP-glucuronosyltransferase 1-10 | Enzyme | C00001837 C00001889 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00001869 C00027467 | 0 / 0 |
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00001889 C00027467 | 1 / 1 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00026092 C00027467 | 0 / 0 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00026092 C00027467 | 0 / 0 |
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00026092 C00027467 | 0 / 0 |
| P22303 | Acetylcholinesterase | Hydrolase | C00001876 C00027467 | 1 / 0 |
| P06133 | UDP-glucuronosyltransferase 2B4 | Enzyme | C00001837 C00001889 | 0 / 0 |
| Q9HAW9 | UDP-glucuronosyltransferase 1-8 | Enzyme | C00001837 C00001889 | 0 / 0 |
| P08183 | Multidrug resistance protein 1 | drug | C00001837 C00001889 | 1 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00001869 C00001876 | 3 / 3 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00001876 C00027467 | 0 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00001876 C00026092 | 0 / 0 |
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00001924 C00026092 | 0 / 0 |
| Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | C00001889 C00027467 | 1 / 0 |
| P16662 | UDP-glucuronosyltransferase 2B7 | Enzyme | C00001837 C00001889 | 0 / 0 |
| P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | C00001889 C00027467 | 0 / 0 |
| P14416 | D(2) dopamine receptor | Dopamine receptor | C00026092 C00027467 | 2 / 0 |
| P54855 | UDP-glucuronosyltransferase 2B15 | Enzyme | C00001837 C00001889 | 0 / 0 |
| P17405 | Sphingomyelin phosphodiesterase | Enzyme | C00001876 C00027467 | 2 / 2 |
| P22309 | UDP-glucuronosyltransferase 1-1 | Enzyme | C00001889 | 5 / 1 |
| Q9Y271 | Cysteinyl leukotriene receptor 1 | Leukotriene receptor | C00027467 | 0 / 0 |
| P29274 | Adenosine receptor A2a | Adenosine receptor | C00027467 | 0 / 0 |
| P25929 | Neuropeptide Y receptor type 1 | Neuropeptide Y receptor | C00027467 | 0 / 0 |
| P50052 | Type-2 angiotensin II receptor | Angiotensin receptor | C00027467 | 1 / 1 |
| P17948 | Vascular endothelial growth factor receptor 1 | Vegfr | C00027467 | 0 / 0 |
| P41968 | Melanocortin receptor 3 | Melanocortin receptor | C00027467 | 1 / 0 |
| P17252 | Protein kinase C alpha type | Alpha | C00027467 | 0 / 0 |
| P37288 | Vasopressin V1a receptor | Vasopressin and oxytocin receptor | C00027467 | 0 / 0 |
| P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | C00027467 | 0 / 0 |
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00027467 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00026092 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00001876 | 0 / 0 |
| Q13370 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | PDE_3B | C00027467 | 0 / 0 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00027467 | 0 / 0 |
| O60656 | UDP-glucuronosyltransferase 1-9 | Enzyme | C00001889 | 0 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00027467 | 0 / 0 |
| P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | C00027467 | 0 / 0 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00027467 | 1 / 8 |
| P21917 | D(4) dopamine receptor | Dopamine receptor | C00027467 | 0 / 0 |
| P30988 | Calcitonin receptor | Calcitonin receptor | C00027467 | 0 / 0 |
| P35462 | D(3) dopamine receptor | Dopamine receptor | C00027467 | 1 / 0 |
| P49146 | Neuropeptide Y receptor type 2 | Neuropeptide Y receptor | C00027467 | 0 / 0 |
| Q92731 | Estrogen receptor beta | NR3A2 | C00027467 | 0 / 1 |
| P41595 | 5-hydroxytryptamine receptor 2B | Serotonin receptor | C00027467 | 0 / 0 |
| P25101 | Endothelin-1 receptor | Endothelin receptor | C00027467 | 0 / 0 |
| P30411 | B2 bradykinin receptor | Bradykinin receptor | C00027467 | 0 / 0 |
| P32245 | Melanocortin receptor 4 | Melanocortin receptor | C00027467 | 1 / 0 |
| P32238 | Cholecystokinin receptor type A | Cholecystokinin receptor | C00027467 | 0 / 0 |
| P08311 | Cathepsin G | S1A | C00027467 | 0 / 0 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00027467 | 2 / 2 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00026092 | 0 / 0 |
| P03956 | Interstitial collagenase | M10A | C00027467 | 0 / 1 |
| P32241 | Vasoactive intestinal polypeptide receptor 1 | Vasoactive intestinal peptide receptor | C00027467 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00001876 | 7 / 3 |
| Q9Y233 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | PDE_10A | C00027467 | 0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00026092 | 1 / 1 |
| Q08209 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Ser_Thr | C00027467 | 0 / 0 |
| Q16539 | Mitogen-activated protein kinase 14 | p38 | C00027467 | 0 / 0 |
| Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | Enzyme | C00026092 | 0 / 0 |
| P06241 | Tyrosine-protein kinase Fyn | Src | C00027467 | 0 / 0 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00027467 | 0 / 1 |
| P08172 | Muscarinic acetylcholine receptor M2 | Acetylcholine receptor | C00027467 | 2 / 0 |
| P11229 | Muscarinic acetylcholine receptor M1 | Acetylcholine receptor | C00027467 | 0 / 0 |
| P21554 | Cannabinoid receptor 1 | Cannabinoid receptor | C00027467 | 0 / 0 |
| P31645 | Sodium-dependent serotonin transporter | Serotonin | C00027467 | 2 / 0 |
| P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | C00027467 | 5 / 9 |
| P20309 | Muscarinic acetylcholine receptor M3 | Acetylcholine receptor | C00027467 | 1 / 0 |
| P21452 | Substance-K receptor | Neurokinin receptor | C00027467 | 0 / 0 |
| P51679 | C-C chemokine receptor type 4 | CC chemokine receptor | C00027467 | 0 / 0 |
| P51681 | C-C chemokine receptor type 5 | CC chemokine receptor | C00027467 | 3 / 0 |
| P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | C00027467 | 0 / 0 |
| P18054 | Arachidonate 12-lipoxygenase, 12S-type | Enzyme | C00027467 | 2 / 0 |
| P41597 | C-C chemokine receptor type 2 | CC chemokine receptor | C00027467 | 1 / 0 |
| P24941 | Cyclin-dependent kinase 2 | Cdc2 | C00025655 | 0 / 0 |
| P08575 | Receptor-type tyrosine-protein phosphatase C | Enzyme | C00027467 | 2 / 1 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00027467 | 0 / 0 |
| P25024 | C-X-C chemokine receptor type 1 | CXC chemokine receptor | C00027467 | 0 / 0 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00001869 | 2 / 2 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00026092 | 0 / 0 |
| P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | C00027467 | 0 / 0 |
| Q9Y4X1 | UDP-glucuronosyltransferase 2A1 | Enzyme | C00001889 | 0 / 0 |
| P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | C00027467 | 0 / 0 |
| P36537 | UDP-glucuronosyltransferase 2B10 | Enzyme | C00001889 | 0 / 0 |
| O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | C00027467 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00027467 | 1 / 1 |
| P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | C00027467 | 1 / 0 |
| P08912 | Muscarinic acetylcholine receptor M5 | Acetylcholine receptor | C00027467 | 0 / 0 |
| Q01959 | Sodium-dependent dopamine transporter | Dopamine | C00027467 | 1 / 0 |
| P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | C00027467 | 0 / 0 |
| P08246 | Neutrophil elastase | S1A | C00027467 | 2 / 1 |
| P08173 | Muscarinic acetylcholine receptor M4 | Acetylcholine receptor | C00027467 | 0 / 0 |
| P25103 | Substance-P receptor | Neurokinin receptor | C00027467 | 0 / 0 |
| P25105 | Platelet-activating factor receptor | PAF receptor | C00027467 | 0 / 0 |
| P33032 | Melanocortin receptor 5 | Melanocortin receptor | C00027467 | 0 / 0 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00027467 | 0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00027467 | 0 / 0 |
| P55210 | Caspase-7 | C14 | C00001869 | 0 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00027467 | 0 / 3 |
| P35367 | Histamine H1 receptor | Histamine receptor | C00027467 | 0 / 0 |
| P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | C00027467 | 0 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00026092 | 1 / 1 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00001869 | 0 / 0 |
| P27361 | Mitogen-activated protein kinase 3 | Erk | C00027467 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00001869 | 4 / 3 |
| P19224 | UDP-glucuronosyltransferase 1-6 | Enzyme | C00001889 | 0 / 0 |
| O14727 | Apoptotic protease-activating factor 1 | Unclassified protein | C00026092 | 0 / 0 |
| P25021 | Histamine H2 receptor | Histamine receptor | C00027467 | 0 / 0 |
| P08908 | 5-hydroxytryptamine receptor 1A | Serotonin receptor | C00026092 | 1 / 0 |
| P23975 | Sodium-dependent noradrenaline transporter | Norepinephrine | C00027467 | 1 / 1 |
| P25100 | Alpha-1D adrenergic receptor | Adrenergic receptor | C00027467 | 0 / 0 |
| P30542 | Adenosine receptor A1 | Adenosine receptor | C00027467 | 0 / 0 |
| Q14432 | cGMP-inhibited 3',5'-cyclic phosphodiesterase A | PDE_3A | C00027467 | 0 / 0 |
| P18089 | Alpha-2B adrenergic receptor | Adrenergic receptor | C00027467 | 0 / 0 |
| P24557 | Thromboxane-A synthase | Cytochrome P450 5A1 | C00027467 | 1 / 1 |
| P06239 | Tyrosine-protein kinase Lck | Src | C00027467 | 0 / 1 |
| O00408 | cGMP-dependent 3',5'-cyclic phosphodiesterase | PDE_2A | C00027467 | 0 / 0 |
| P25025 | C-X-C chemokine receptor type 2 | CXC chemokine receptor | C00027467 | 0 / 0 |
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | C00027467 | 0 / 1 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00027467 | 1 / 2 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00001869 | 0 / 0 |
| P40225 | Thrombopoietin | Unclassified protein | C00027467 | 1 / 1 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00027467 | 3 / 2 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00026092 | 1 / 0 |
| Q8IUX4 | DNA dC->dU-editing enzyme APOBEC-3F | Enzyme | C00026092 | 0 / 0 |
| O00255 | Menin | Unclassified protein | C00001869 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00001869 | 1 / 2 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00001869 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00001869 | 1 / 4 |
| Q14123 | Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C | PDE_1C | C00027467 | 0 / 0 |
| P54750 | Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A | PDE_1A | C00027467 | 0 / 0 |
| Q01064 | Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B | PDE_1B | C00027467 | 0 / 0 |
| P27815 | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | PDE_4A | C00027467 | 0 / 0 |
| Q08499 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | PDE_4D | C00027467 | 1 / 0 |
| Q07343 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | PDE_4B | C00027467 | 0 / 0 |
| Q08493 | cAMP-specific 3',5'-cyclic phosphodiesterase 4C | PDE_4C | C00027467 | 0 / 0 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00027467 | 4 / 1 |
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00001869 | 7 / 37 |
| Q92793 | CREB-binding protein | Enzyme | C00027467 | 1 / 1 |
| O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | C00027467 | 0 / 0 |
75 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 6352 | CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP | chemokine (C-C motif) ligand 5 |
C00001837
C00001889
|
| 1565 | CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1 | cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1) |
C00001837
C00001889
|
| 407056 | MIR99B, MIRN99B | microRNA 99b |
C00001889
|
| 1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) |
C00001837
|
| 3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00001837
|
| 3757 | KCNH2, ERG1, HERG, HERG1, Kv11.1, LQT2, SQT1 | potassium voltage-gated channel, subfamily H (eag-related), member 2 |
C00001837
|
| 207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) |
C00001889
|
| 338 | APOB, FLDB, LDLCQ4 | apolipoprotein B |
C00001889
|
| 10550 | ARL6IP5, DERP11, GTRAP3-18, JWA, PRAF3, addicsin, hp22, jmx | ADP-ribosylation-like factor 6 interacting protein 5 |
C00001889
|
| 409 | ARRB2, ARB2, ARR2, BARR2 | arrestin, beta 2 |
C00001889
|
| 578 | BAK1, BAK, BAK-LIKE, BCL2L7, CDN1 | BCL2-antagonist/killer 1 |
C00001889
|
| 581 | BAX, BCL2L4 | BCL2-associated X protein |
C00001889
|
| 27113 | BBC3, JFY-1, JFY1, PUMA | BCL2 binding component 3 |
C00001889
|
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00001889
|
| 10018 | BCL2L11, BAM, BIM, BOD | BCL2-like 11 (apoptosis facilitator) |
C00001889
|
| 8678 | BECN1, ATG6, VPS30, beclin1 | beclin 1, autophagy related |
C00001889
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00001889
|
| 841 | CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 | caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) |
C00001889
|
| 842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00001889
|
| 6355 | CCL8, HC14, MCP-2, MCP2, SCYA10, SCYA8 | chemokine (C-C motif) ligand 8 |
C00001889
|
| 1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
C00001889
|
| 8824 | CES2, CE-2, CES2A1, PCE-2, iCE | carboxylesterase 2 (EC:3.1.1.1 3.1.1.84 3.1.1.56) |
C00001889
|
| 1312 | COMT | catechol-O-methyltransferase (EC:2.1.1.6) |
C00001889
|
| 1401 | CRP, PTX1 | C-reactive protein, pentraxin-related |
C00001889
|
| 54205 | CYCS, CYC, HCS, THC4 | cytochrome c, somatic |
C00001889
|
| 1643 | DDB2, DDBB, UV-DDB2 | damage-specific DNA binding protein 2, 48kDa |
C00001889
|
| 1984 | EIF5A, EIF-5A, EIF5A1, eIF5AI | eukaryotic translation initiation factor 5A |
C00001889
|
| 2155 | F7, SPCA | coagulation factor VII (serum prothrombin conversion accelerator) (EC:3.4.21.21) |
C00001889
|
| 355 | FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6 | Fas cell surface death receptor |
C00001889
|
| 2247 | FGF2, BFGF, FGF-2, FGFB, HBGF-2 | fibroblast growth factor 2 (basic) |
C00001889
|
| 3557 | IL1RN, DIRA, ICIL-1RA, IL-1RN, IL-1ra, IL-1ra3, IL1F3, IL1RA, IRAP, MVCD4 | interleukin 1 receptor antagonist |
C00001889
|
| 3569 | IL6, BSF2, HGF, HSF, IFNB2, IL-6 | interleukin 6 (interferon, beta 2) |
C00001889
|
| 3725 | JUN, AP-1, AP1, c-Jun | jun proto-oncogene |
C00001889
|
| 8609 | KLF7, UKLF | Kruppel-like factor 7 (ubiquitous) |
C00001889
|
| 4010 | LMX1B, LMX1.2, NPS1 | LIM homeobox transcription factor 1, beta |
C00001889
|
| 5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00001889
|
| 5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00001889
|
| 406901 | MIR107, MIRN107, miR-107 | microRNA 107 |
C00001889
|
| 406921 | MIR132, MIRN132, miRNA132 | microRNA 132 |
C00001889
|
| 100302258 | MIR1469, MIRN1469, hsa-mir-1469 | microRNA 1469 |
C00001889
|
| 406938 | MIR146A, MIRN146, MIRN146A, miR-146a, miRNA146A | microRNA 146a |
C00001889
|
| 406942 | MIR150, MIRN150, miRNA150 | microRNA 150 |
C00001889
|
| 406947 | MIR155, MIRN155, miRNA155 | microRNA 155 |
C00001889
|
| 406949 | MIR15B, MIRN15B, hsa-mir-15b, miR-15b | microRNA 15b |
C00001889
|
| 406966 | MIR191, MIRN191, miR-191 | microRNA 191 |
C00001889
|
| 100302129 | MIR1915, MIRN1915, hsa-mir-1915 | microRNA 1915 |
C00001889
|
| 406991 | MIR21, MIRN21, hsa-mir-21, miR-21, miRNA21 | microRNA 21 |
C00001889
|
| 407006 | MIR221, MIRN221, miRNA221, mir-221 | microRNA 221 |
C00001889
|
| 407010 | MIR23A, MIRN23A, hsa-mir-23a, miRNA23A | microRNA 23a |
C00001889
|
| 407011 | MIR23B, MIRN23B, hsa-mir-23b, miRNA23B | microRNA 23b |
C00001889
|
| 407015 | MIR26A1, MIR26A, MIRN26A1 | microRNA 26a-1 |
C00001889
|
| 407017 | MIR26B, MIRN26B, hsa-mir-26b, miR-26b | microRNA 26b |
C00001889
|
| 407037 | MIR320A, MIRN320, MIRN320A, hsa-mir-320a | microRNA 320a |
C00001889
|
| 494335 | MIR423, MIRN423, hsa-mir-423 | microRNA 423 |
C00001889
|
| 693223 | MIR638, MIRN638, hsa-mir-638 | microRNA 638 |
C00001889
|
| 6347 | CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF | chemokine (C-C motif) ligand 2 |
C00001837
|
| 4792 | NFKBIA, IKBA, MAD-3, NFKBI | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
C00001889
|
| 4814 | NINJ1, NIN1, NINJURIN | ninjurin 1 |
C00001889
|
| 4985 | OPRD1, OPRD | opioid receptor, delta 1 |
C00001889
|
| 4988 | OPRM1, LMOR, M-OR-1, MOP, MOR, MOR1, OPRM | opioid receptor, mu 1 |
C00001889
|
| 5155 | PDGFB, IBGC5, PDGF-2, PDGF2, SIS, SSV, c-sis | platelet-derived growth factor beta polypeptide |
C00001889
|
| 5443 | POMC, ACTH, CLIP, LPH, MSH, NPP, POC | proopiomelanocortin |
C00001889
|
| 84152 | PPP1R1B, DARPP-32, DARPP32 | protein phosphatase 1, regulatory (inhibitor) subunit 1B (EC:3.1.3.16) |
C00001889
|
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00001889
|
| 6648 | SOD2, IPOB, MNSOD, MVCD6 | superoxide dismutase 2, mitochondrial (EC:1.15.1.1) |
C00001889
|
| 6778 | STAT6, D12S1644, IL-4-STAT, STAT6B, STAT6C | signal transducer and activator of transcription 6, interleukin-4 induced |
C00001889
|
| 7099 | TLR4, ARMD10, CD284, TLR-4, TOLL | toll-like receptor 4 |
C00001889
|
| 7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00001889
|
| 54658 | UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A | UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) |
C00001889
|
| 54575 | UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J | UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) |
C00001889
|
| 54659 | UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C | UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) |
C00001889
|
| 54578 | UGT1A6, GNT1, HLUGP, HLUGP1, UDPGT, UDPGT_1-6, UGT1, UGT1A6S, UGT1F | UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17) |
C00001889
|
| 54576 | UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H | UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) |
C00001889
|
| 54600 | UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I | UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) |
C00001889
|
| 7364 | UGT2B7, UDPGT_2B9, UDPGT2B7, UDPGTH2, UGT2B9 | UDP glucuronosyltransferase 2 family, polypeptide B7 (EC:2.4.1.17) |
C00001889
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (100)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #100100 | Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism |
P20309
|
| #614613 | Acrodysostosis 2, with or without hormone resistance; acrdys2 |
Q08499
|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #103780 | Alcohol dependence |
P08172
P14416 P31645 |
| #614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #601816 | Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 |
P22309
|
| #602025 | Body mass index quantitative trait locus 9; bmiq9 |
P41968
|
| #300615 | Brunner syndrome |
P21397
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #114500 | Colorectal cancer; crc |
P18054
|
| #218800 | Crigler-najjar syndrome, type i |
P22309
P22310 |
| #606785 | Crigler-najjar syndrome, type ii |
P22309
P22310 |
| #162800 | Cyclic neutropenia |
P08246
|
| #612522 | Diabetes mellitus, insulin-dependent, 22; iddm22 |
P51681
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #607208 | Dravet syndrome |
P35498
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #613721 | Epileptic encephalopathy, early infantile, 11; eiee11 |
Q99250
|
| #133239 | Esophageal cancer |
P04637
P18054 |
| #615363 | Estrogen resistance; estrr |
P03372
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #613659 | Gastric cancer |
P04626
|
| #137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
| #604403 | Generalized epilepsy with febrile seizures plus, type 2; gefsp2 |
P35498
|
| #231095 | Ghosal hematodiaphyseal dysplasia; ghdd |
P24557
|
| #143500 | Gilbert syndrome |
P22309
P22310 |
| #137800 | Glioma susceptibility 1; glm1 |
O75874
P04626 |
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #609423 | Human immunodeficiency virus type 1, susceptibility to |
P41597
P51681 |
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #237900 | Hyperbilirubinemia, transient familial neonatal; hblrtfn |
P22309
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P00533
P04626 P04637 |
| #608516 | Major depressive disorder; mdd |
P08172
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| %300852 | Mental retardation, x-linked 88; mrx88 |
P50052
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #609634 | Migraine, familial hemiplegic, 3; fhm3 |
P35498
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #126200 | Multiple sclerosis, susceptibility to; ms |
P08575
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #159900 | Myoclonic dystonia |
P14416
|
| #202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 |
P08246
|
| #257200 | Niemann-pick disease, type a |
P17405
|
| #607616 | Niemann-pick disease, type b |
P17405
|
| #601665 | Obesity |
P32245
|
| #164230 | Obsessive-compulsive disorder; ocd |
P31645
|
| #604715 | Orthostatic intolerance |
P23975
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #167000 | Ovarian cancer |
P04626
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #613135 | Parkinsonism-dystonia, infantile; pkdys |
Q01959
|
| #614674 | Periodic fever, menstrual cycle-dependent |
P08908
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #607276 | Resting heart rate, variation in |
P08588
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #180849 | Rubinstein-taybi syndrome 1; rsts1 |
Q92793
|
| #607745 | Seizures, benign familial infantile, 3; bfis3 |
Q99250
|
| #608971 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive |
P08575
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #187950 | Thrombocythemia 1; thcyt1 |
P40225
|
| #190300 | Tremor, hereditary essential, 1; etm1 |
P35462
|
| #610379 | West nile virus, susceptibility to |
P51681
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
| #112100 | Yt blood group antigen |
P22303
|
KEGG DISEASE (96)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P04637 (related) P04637 (marker) P35354 (related) |
| H00018 | Gastric cancer |
P00533
(related)
P04626 (related) P04637 (related) |
| H00022 | Bladder cancer |
P00533
(related)
P04626 (related) P04637 (related) |
| H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P04626 (related) P04637 (related) |
| H00030 | Cervical cancer |
P00533
(related)
P04626 (related) |
| H00042 | Glioma |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04626 (related) P04637 (related) Q92731 (marker) |
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
| H00019 | Pancreatic cancer |
P04626
(related)
P04637 (related) P04637 (marker) |
| H00027 | Ovarian cancer |
P04626
(related)
P04637 (related) |
| H00031 | Breast cancer |
P04626
(related)
P04626 (marker) P04637 (related) |
| H00046 | Cholangiocarcinoma |
P04626
(related)
P04637 (related) P35354 (related) |
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
Q01196 (related) |
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) P14780 (related) P35354 (related) |
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
|
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
|
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00021 | Renal cell carcinoma |
P04637
(marker)
|
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00079 | Asthma |
P07550
(related)
|
| H00100 | Neutropenic disorders |
P08246
(related)
|
| H00091 | T-B+Severe combined immunodeficiencies (SCIDs) |
P08575
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00137 | Niemann-Pick disease (NPD) typeA and B |
P17405
(related)
|
| H00424 | Defects in the degradation of sphingomyelin |
P17405
(related)
|
| H00548 | Brunner syndrome |
P21397
(related)
|
| H00208 | Hyperbilirubinemia |
P22309
(related)
|
| H01031 | Orthostatic intolerance (OI) |
P23975
(related)
|
| H00490 | Diaphyseal dysplasia with anemia (Ghosal) |
P24557
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00775 | Familial or sporadic hemiplegic migraine |
P35498
(related)
|
| H00783 | Febrile seizures |
P35498
(related)
|
| H00227 | Congenital amegakaryocytic thrombocytopenia (CAMT) |
P40225
(marker)
|
| H00480 | Non-syndromic X-linked mental retardation |
P50052
(related)
Q99714 (related) |
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00504 | Rubinstein-Taybi syndrome |
Q92793
(related)
|
| H00606 | Early infantile epileptic encephalopathy |
Q99250
(related)
|
| H00806 | Benign familial neonatal and infantile epilepsies |
Q99250
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|
Diseases related to CTD interactions
228 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D012640 | Seizures |
C00001876
C00001837 C00001889 |
| D011537 | Pruritus |
C00001837
C00001889 |
| D014839 | Vomiting |
C00001837
C00001889 |
| D000860 | Anoxia |
C00001837
C00001889 |
| D001049 | Apnea |
C00001837
C00001889 |
| D013610 | Tachycardia |
C00001837
C00001889 |
| D001919 | Bradycardia |
C00001837
C00001889 |
| D013375 | Substance Withdrawal Syndrome |
C00001837
C00001889 |
| D002375 | Catalepsy |
C00001837
C00001889 |
| D019966 | Substance-Related Disorders |
C00001837
C00001889 |
| D003128 | COMA |
C00001837
C00001889 |
| D003248 | Constipation |
C00001837
C00001889 |
| D003371 | Cough |
C00001837
C00001889 |
| D046628 | Sphincter of Oddi Dysfunction |
C00001837
C00001889 |
| D003693 | Delirium |
C00001837
C00001889 |
| D013035 | Spasm |
C00001837
C00001889 |
| D003967 | Diarrhea |
C00001837
C00001889 |
| D004244 | Dizziness |
C00001837
C00001889 |
| D015746 | Abdominal Pain |
C00001837
C00001889 |
| D011297 | Prenatal Exposure Delayed Effects |
C00001837
C00001889 |
| D010149 | Pain, Postoperative |
C00001837
C00001889 |
| D010146 | Pain |
C00001837
C00001889 |
| D009357 | Neonatal Abstinence Syndrome |
C00001837
C00001889 |
| D005076 | Exanthema |
C00001837
C00001889 |
| D005334 | Fever |
C00001837
C00001889 |
| D009325 | Nausea |
C00001837
C00001889 |
| D005767 | Gastrointestinal Diseases |
C00001837
C00001889 |
| D006261 | Headache |
C00001837
C00001889 |
| D009207 | Myoclonus |
C00001837
C00001889 |
| D006930 | Hyperalgesia |
C00001837
C00001889 |
| D009120 | Muscle Cramp |
C00001837
C00001889 |
| D006973 | Hypertension |
C00001837
C00001889 |
| D007008 | Hypokalemia |
C00001837
C00001889 |
| D018476 | Hypokinesia |
C00001837
C00001889 |
| D007022 | Hypotension |
C00001837
C00001889 |
| D007024 | Hypotension, Orthostatic |
C00001837
C00001889 |
| D007674 | Kidney Diseases |
C00001837
C00001889 |
| D012120 | Respiration Disorders |
C00001889
|
| D007680 | Kidney Neoplasms |
C00001837
|
| D007681 | Kidney Papillary Necrosis |
C00001837
|
| D006967 | Hypersensitivity |
C00001837
|
| D006330 | Heart Defects, Congenital |
C00001837
|
| D005494 | Folic Acid Deficiency |
C00001837
|
| D053159 | Dysuria |
C00001837
|
| D009461 | Neurologic Manifestations |
C00001837
|
| D009771 | Obsessive-Compulsive Disorder |
C00001837
|
| D004421 | Dystonia |
C00001837
|
| D004415 | Dyspepsia |
C00001837
|
| D010195 | Pancreatitis |
C00001837
|
| D003875 | Drug Eruptions |
C00001837
|
| D004310 | Double Outlet Right Ventricle |
C00001837
|
| D011695 | Purpura, Schoenlein-Henoch |
C00001837
|
| D011776 | Pyuria |
C00001837
|
| D012185 | Retroperitoneal Fibrosis |
C00001837
|
| D012216 | Rheumatic Diseases |
C00001837
|
| D012871 | Skin Diseases |
C00001837
|
| D012891 | Sleep Apnea Syndromes |
C00001837
|
| D003866 | Depressive Disorder |
C00001837
|
| D003490 | Cyanosis |
C00001837
|
| D020521 | Stroke |
C00001837
|
| D003085 | Colic |
C00001837
|
| D002295 | Carcinoma, Transitional Cell |
C00001837
|
| D001660 | Biliary Tract Diseases |
C00001837
|
| D014517 | Ureteral Obstruction |
C00001837
|
| D014806 | Vitamin B 12 Deficiency |
C00001837
|
| D000740 | Anemia |
C00001837
|
| D000014 | Abnormalities, Drug-Induced |
C00001889
|
| D000142 | Acidosis, Respiratory |
C00001889
|
| D056586 | Acute Chest Syndrome |
C00001889
|
| D058186 | Acute Kidney Injury |
C00001889
|
| D000219 | Adams-Stokes Syndrome |
C00001889
|
| D000307 | Adrenal Gland Diseases |
C00001889
|
| D019973 | Alcohol-Related Disorders |
C00001889
|
| D000647 | Amnesia |
C00001889
|
| D000707 | Anaphylaxis |
C00001889
|
| D000855 | Anorexia |
C00001889
|
| D001002 | Anuria |
C00001889
|
| D001008 | Anxiety Disorders |
C00001889
|
| D001145 | Arrhythmias, Cardiac |
C00001889
|
| D001281 | Atrial Fibrillation |
C00001889
|
| D054537 | Atrioventricular Block |
C00001889
|
| D001284 | Atrophy |
C00001889
|
| D001416 | Back Pain |
C00001889
|
| D001480 | Basal Ganglia Diseases |
C00001889
|
| D001714 | Bipolar Disorder |
C00001889
|
| D001927 | Brain Diseases |
C00001889
|
| D002545 | Brain Ischemia |
C00001889
|
| D002056 | Burns |
C00001889
|
| D002194 | Capgras Syndrome |
C00001889
|
| D002311 | Cardiomyopathy, Dilated |
C00001889
|
| D002389 | Catatonia |
C00001889
|
| D002637 | Chest Pain |
C00001889
|
| D002764 | Cholecystitis |
C00001889
|
| D002769 | Cholelithiasis |
C00001889
|
| D002779 | Cholestasis |
C00001889
|
| D003072 | Cognition Disorders |
C00001889
|
| D003110 | Colonic Neoplasms |
C00001889
|
| D003137 | Common Bile Duct Diseases |
C00001889
|
| D020918 | Complex Regional Pain Syndromes |
C00001889
|
| D003221 | Confusion |
C00001889
|
| D003244 | Consciousness Disorders |
C00001889
|
| D003327 | Coronary Disease |
C00001889
|
| D055191 | Delayed Emergence from Anesthesia |
C00001889
|
| D003731 | Dental Caries |
C00001889
|
| D003919 | Diabetes Insipidus |
C00001889
|
| D004108 | Dilatation, Pathologic |
C00001889
|
| D004172 | Diplopia |
C00001889
|
| D018450 | Disease Progression |
C00001889
|
| D006970 | Disorders of Excessive Somnolence |
C00001889
|
| D004213 | Dissociative Disorders |
C00001889
|
| D004342 | Drug Hypersensitivity |
C00001889
|
| D056486 | Drug-Induced Liver Injury |
C00001889
|
| D062787 | Drug Overdose |
C00001889
|
| D064420 | Drug-Related Side Effects and Adverse Reactions |
C00001889
|
| D004409 | Dyskinesia, Drug-Induced |
C00001889
|
| D004417 | Dyspnea |
C00001889
|
| D004487 | Edema |
C00001889
|
| D004673 | Encephalomyelitis, Acute Disseminated |
C00001889
|
| D004831 | Epilepsies, Myoclonic |
C00001889
|
| D004827 | Epilepsy |
C00001889
|
| D004830 | Epilepsy, Tonic-Clonic |
C00001889
|
| D005094 | Exophthalmos |
C00001889
|
| D005157 | Facial Pain |
C00001889
|
| D005221 | Fatigue |
C00001889
|
| D005242 | Fecal Incontinence |
C00001889
|
| D042882 | Gallstones |
C00001889
|
| D006099 | Granuloma |
C00001889
|
| D006212 | Hallucinations |
C00001889
|
| D006331 | Heart Diseases |
C00001889
|
| D006417 | Hematuria |
C00001889
|
| D006429 | Hemiplegia |
C00001889
|
| D006470 | Hemorrhage |
C00001889
|
| D006501 | Hepatic Encephalopathy |
C00001889
|
| D006526 | Hepatitis C |
C00001889
|
| D006556 | Heroin Dependence |
C00001889
|
| D006560 | Herpes Labialis |
C00001889
|
| D006606 | Hiccup |
C00001889
|
| D006819 | Hyaline Membrane Disease |
C00001889
|
| D006869 | Hydronephrosis |
C00001889
|
| D006935 | Hypercapnia |
C00001889
|
| D006940 | Hyperemia |
C00001889
|
| D006941 | Hyperesthesia |
C00001889
|
| D006948 | Hyperkinesis |
C00001889
|
| D006987 | Hypesthesia |
C00001889
|
| D007006 | Hypogonadism |
C00001889
|
| D007018 | Hypopituitarism |
C00001889
|
| D007035 | Hypothermia |
C00001889
|
| D002534 | Hypoxia, Brain |
C00001889
|
| D019586 | Intracranial Hypertension |
C00001889
|
| D048949 | Labor Pain |
C00001889
|
| D007826 | Laryngismus |
C00001889
|
| D007859 | Learning Disorders |
C00001889
|
| D053609 | Lethargy |
C00001889
|
| D017116 | Low Back Pain |
C00001889
|
| D008175 | Lung Neoplasms |
C00001889
|
| D008305 | Malignant Hyperthermia |
C00001889
|
| D008569 | Memory Disorders |
C00001889
|
| D015877 | Miosis |
C00001889
|
| D009021 | Morphine Dependence |
C00001889
|
| D009069 | Movement Disorders |
C00001889
|
| D052016 | Mucositis |
C00001889
|
| D009122 | Muscle Hypertonia |
C00001889
|
| D009123 | Muscle Hypotonia |
C00001889
|
| D009127 | Muscle Rigidity |
C00001889
|
| D009128 | Muscle Spasticity |
C00001889
|
| D018908 | Muscle Weakness |
C00001889
|
| D015878 | Mydriasis |
C00001889
|
| D009203 | Myocardial Infarction |
C00001889
|
| D017202 | Myocardial Ischemia |
C00001889
|
| D015428 | Myocardial Reperfusion Injury |
C00001889
|
| D009290 | Narcolepsy |
C00001889
|
| D009336 | Necrosis |
C00001889
|
| D009422 | Nervous System Diseases |
C00001889
|
| D009437 | Neuralgia |
C00001889
|
| D009436 | Neural Tube Defects |
C00001889
|
| D020258 | Neurotoxicity Syndromes |
C00001889
|
| D009759 | Nystagmus, Pathologic |
C00001889
|
| D009846 | Oliguria |
C00001889
|
| D009293 | Opioid-Related Disorders |
C00001889
|
| D010148 | Pain, Intractable |
C00001889
|
| D010243 | Paralysis |
C00001889
|
| D010259 | Paranoid Disorders |
C00001889
|
| D020335 | Paraparesis |
C00001889
|
| D020336 | Paraparesis, Spastic |
C00001889
|
| D010291 | Paresis |
C00001889
|
| D010523 | Peripheral Nervous System Diseases |
C00001889
|
| D010538 | Peritonitis |
C00001889
|
| D010554 | Personality Disorders |
C00001889
|
| D020250 | Postoperative Nausea and Vomiting |
C00001889
|
| D011595 | Psychomotor Agitation |
C00001889
|
| D011596 | Psychomotor Disorders |
C00001889
|
| D011605 | Psychoses, Substance-Induced |
C00001889
|
| D011654 | Pulmonary Edema |
C00001889
|
| D011681 | Pupil Disorders |
C00001889
|
| D012021 | Reflex, Abnormal |
C00001889
|
| D001405 | Reflex, Babinski |
C00001889
|
| D051437 | Renal Insufficiency |
C00001889
|
| D015427 | Reperfusion Injury |
C00001889
|
| D007232 | Infant, Newborn, Diseases |
C00001837
|
| D012131 | Respiratory Insufficiency |
C00001889
|
| D012206 | Rhabdomyolysis |
C00001889
|
| D012585 | Sciatica |
C00001889
|
| D012769 | Shock |
C00001889
|
| D020182 | Sleep Apnea, Central |
C00001889
|
| D020181 | Sleep Apnea, Obstructive |
C00001889
|
| D012892 | Sleep Deprivation |
C00001889
|
| D012893 | Sleep Disorders |
C00001889
|
| D013064 | Speech Disorders |
C00001889
|
| D013117 | Spinal Cord Compression |
C00001889
|
| D013118 | Spinal Cord Diseases |
C00001889
|
| D013203 | Staphylococcal Infections |
C00001889
|
| D013226 | Status Epilepticus |
C00001889
|
| D019956 | Stereotypic Movement Disorder |
C00001889
|
| D053608 | Stupor |
C00001889
|
| D013705 | Temporomandibular Joint Disorders |
C00001889
|
| D018677 | Tooth Injuries |
C00001889
|
| D016388 | Tooth Loss |
C00001889
|
| D014474 | Unconsciousness |
C00001889
|
| D053201 | Urinary Bladder, Overactive |
C00001889
|
| D014549 | Urinary Incontinence |
C00001889
|
| D016055 | Urinary Retention |
C00001889
|
| D014555 | Urination Disorders |
C00001889
|
| D018487 | Ventricular Dysfunction, Left |
C00001889
|
| D018879 | Ventricular Premature Complexes |
C00001889
|
| D014717 | Vertigo |
C00001889
|
| D014786 | Vision Disorders |
C00001889
|
| D015431 | Weight Loss |
C00001889
|
| D014987 | Xerostomia |
C00001889
|