Linum usitatissimum

• Index
• Plant Species
• Metabolite list (33)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Linum usitatissimum
Genus	Linum
Family	Linaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Linum usitatissimum
Linked NCBI taxonomy ID	4006
Linked level	species

Family

Family in NCBI taxonomy	Linaceae
ID	4004

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (33)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00007247	Linolenic acid / alpha-Linolenic acid / (Z,Z,Z)-Octadeca-9,12,15-trienoic acid		D017962		22 / 5
C00006204	Orientin 7-O-rhamnoside					No. 1	No. 15
C00006231	Lucenin 2 / Luteolin 6,8-C-diglucoside					No. 1	No. 15
C00005149	Populnin / Kaempferol 7-glucoside	CHEMBL469441 CHEMBL1159471				No. 2	No. 15
C00006410	Lucenin-2,7-O-rhamnoside					No. 5	No. 15
C00007190	(+)-Pinoresinol	CHEMBL267963 CHEMBL487611 CHEMBL460862	C103298	7 / 5 / 6		No. 38	No. 21
C00000587	(-)-Pinoresinol	CHEMBL267963 CHEMBL487611 CHEMBL460862		7 / 5 / 6		No. 38	No. 21
C00003650	Cycloartenol	CHEMBL119938 CHEMBL225815 CHEMBL226036 CHEMBL393145 CHEMBL2007217	C100089		0 / 1	No. 129	No. 11
C00000652	(+)-Secoisolariciresinol diglucoside					No. 152
C00000606	(-)-Matairesinol	CHEMBL425148	C068935	1 / 0 / 0		No. 223	No. 21
C00001448	Lotaustralin / (R)-Lotaustralin		C001556			No. 258	No. 73
C00001446	Linamarin	CHEMBL1590222	C005091	1 / 4 / 3		No. 258	No. 73
C00000605	(+)-Secoisolariciresinol	CHEMBL368347		2 / 1 / 1		No. 282	No. 21
C00000604	(-)-Secoisolariciresinol	CHEMBL368347	C060283	2 / 1 / 1	1 / 0	No. 282	No. 21
C00000614	Coniferyl alcohol	CHEMBL501870 CHEMBL2088631	C010559			No. 310	No. 6
C00002728	Coniferaldehyde / Coniferyl aldehyde / 4-Hydroxy-3-methoxycinnamaldehyde	CHEMBL242529 CHEMBL1956165	C075384	1 / 1 / 1		No. 310	No. 6
C00003428	Geranylgeraniol	CHEMBL478589		3 / 4 / 3		No. 369	No. 38
C00001447	Linustatin		C023022		0 / 2	No. 423	No. 73
C00001450	Neolinustatin		C023031		0 / 2	No. 423	No. 73
C00000603	(-)-Lariciresinol	CHEMBL518421	C060282	2 / 1 / 1		No. 700	No. 21
C00000218	Jasmonic acid / trans-Jasmonic acid / 3-Oxo-2-(2Z-pentenyl)cyclotentylacetic acid	CHEMBL445499 CHEMBL449572	C011006	4 / 1 / 0		No. 707	No. 70
C00000446	7-iso-Jasmonic acid / (+)-Epijasmonic acid	CHEMBL445499 CHEMBL449572		4 / 1 / 0		No. 707	No. 70
C00000366	OPC-8:0 / 3-Oxo-2-(2-entenyl)cyclopentaneoctanoic acid					No. 707	No. 70
C00000361	OPC-4:0					No. 707	No. 70
C00027048	Cyclolinopeptide I					No. 1065
C00027044	Cyclolinopeptide G					No. 1065
C00027046	Cyclolinopeptide H					No. 1065
C00027043	Cyclolinopeptide F					No. 1065
C00036983	Cyclolinopeptide A	CHEMBL1793995				No. 1065
C00036984	Cyclolinopeptide B / (-)-Cyclolinopeptide B					No. 1065
C00036985	Cyclolinopeptide C					No. 1065
C00036986	Cyclolinopeptide D / (-)-Cyclolinopeptide D					No. 1065
C00036987	Cyclolinopeptide E / (-)-Cyclolinopeptide E					No. 1065

Human Protein / Gene in interactions

18 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000603 C00000604 C00000605	1 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000603 C00000604 C00000605	0 / 1
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00000587 C00007190	5 / 3
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00000587 C00007190	0 / 3
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00000587 C00007190	0 / 0
Q9H0H5	Rac GTPase-activating protein 1	Unclassified protein	C00000587 C00007190	0 / 0
Q07869	Peroxisome proliferator-activated receptor alpha	NR1C1	C00000587 C00007190	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00001446 C00003428	4 / 3
P42330	Aldo-keto reductase family 1 member C3	Enzyme	C00000218 C00000446	0 / 0
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00000587 C00007190	0 / 0
P52895	Aldo-keto reductase family 1 member C2	Enzyme	C00000218 C00000446	1 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00000587 C00007190	0 / 0
P17516	Aldo-keto reductase family 1 member C4	Enzyme	C00000218 C00000446	1 / 0
Q04828	Aldo-keto reductase family 1 member C1	Enzyme	C00000218 C00000446	0 / 0
P04278	Sex hormone-binding globulin	Secreted protein	C00000606	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00003428	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00003428	0 / 0
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00002728	1 / 1

23 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
8856	NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR	nuclear receptor subfamily 1, group I, member 2	C00000604
8647	ABCB11, ABC16, BRIC2, BSEP, PFIC-2, PFIC2, PGY4, SPGP	ATP-binding cassette, sub-family B (MDR/TAP), member 11	C00007247
1374	CPT1A, CPT1, CPT1-L, L-CPT1	carnitine palmitoyltransferase 1A (liver) (EC:2.3.1.21)	C00007247
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00007247
1591	CYP24A1, CP24, CYP24, HCAI, P450-CC24	cytochrome P450, family 24, subfamily A, polypeptide 1 (EC:1.14.13.126)	C00007247
1557	CYP2C19, CPCJ, CYP2C, P450C2C, P450IIC19	cytochrome P450, family 2, subfamily C, polypeptide 19 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00007247
1559	CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9	cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00007247
1571	CYP2E1, CPE1, CYP2E, P450-J, P450C2E	cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7)	C00007247
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00007247
3992	FADS1, D5D, FADS6, FADSD5, LLCDL1, TU12	fatty acid desaturase 1 (EC:1.14.19.-)	C00007247
2729	GCLC, GCL, GCS, GLCL, GLCLC	glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2)	C00007247
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00007247
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00007247
3565	IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4	interleukin 4	C00007247
3827	KNG1, BDK, BK, KNG	kininogen 1	C00007247
9971	NR1H4, BAR, FXR, HRR-1, HRR1, RIP14	nuclear receptor subfamily 1, group H, member 4	C00007247
5465	PPARA, NR1C1, PPAR, PPARalpha, hPPAR	peroxisome proliferator-activated receptor alpha	C00007247
100136658			C00007247
5467	PPARD, FAAR, NR1C2, NUC1, NUCI, NUCII, PPARB	peroxisome proliferator-activated receptor delta	C00007247
5468	PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma	peroxisome proliferator-activated receptor gamma	C00007247
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00007247
6256	RXRA, NR2B1	retinoid X receptor, alpha	C00007247
7421	VDR, NR1I1	vitamin D (1,25- dihydroxyvitamin D3) receptor	C00007247

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions