Species

KNApSAcK Entry

Organism name Thujopsis dolabrata
Genus Thujopsis
Family Cupressaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Thujopsis dolabrata
Linked NCBI taxonomy ID 13727
Linked level species

Family

Family in NCBI taxonomy Cupressaceae
ID 3367

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Spermatophyta
ID 58024

Metabolite list (24)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00008695 External link 512 (2R,3S)-Epitaxifolin 3-xyloside
CHEMBL2332674
CHEMBL2332675
CHEMBL2332676
CHEMBL2332677
No. 12 No. 14
C00008694 External link 512 (2R,3R)-Taxifolin 3-xyloside
CHEMBL2332674
CHEMBL2332675
CHEMBL2332676
CHEMBL2332677
No. 12 No. 14
C00008696 External link 512 (2S,3R)-Epitaxifolin 3-xyloside
CHEMBL2332674
CHEMBL2332675
CHEMBL2332676
CHEMBL2332677
No. 12 No. 14
C00008697 External link 512 (2S,3S)-Taxifolin 3-xyloside
CHEMBL2332674
CHEMBL2332675
CHEMBL2332676
CHEMBL2332677
No. 12 No. 14
C00009089 External link 512 Arecatannin B1
CHEMBL592329
2 / 3 / 4 No. 29 No. 19
C00006537 External link 512 Chamaecyparin
No. 34 No. 18
C00006536 External link 512 Cryptomerin A
No. 34 No. 18
C00012750 External link 512 (+)-Costal
/ Costic aldehyde
/ (+)-beta-Costal
/ Eudesma-4(14),11(13)-dien-12-al
CHEMBL362552
No. 151 No. 38
C00022707 External link 512 Isoagatholal
No. 165
C00012509 External link 512 gamma-Cuparenol
No. 309
C00003194 External link 512 Thujopsene
No. 365 No. 38
C00002616 External link 512 beta-Peltatin A methyl ether
CHEMBL483004
C010499
No. 427 No. 21
C00007208 External link 512 beta-Peltatin
/ (-)-beta-Peltatin
CHEMBL97543
CHEMBL443566
CHEMBL1435754
9 / 16 / 14 No. 427 No. 21
C00002597 External link 512 Deoxypodophyllotoxin
/ (-)-Deoxypodophyllotoxin
CHEMBL63970
CHEMBL149525
CHEMBL152144
CHEMBL255919
CHEMBL519603
CHEMBL476679
CHEMBL1736070
7 / 4 / 2 No. 427 No. 21
C00012529 External link 512 4-Cuprenene
/ Buprenene IV
/ gamma-Cuprenene
No. 451 No. 38
C00021952 External link 512 Isowiddrene
/ alpha-Pseudowiddrene
No. 451 No. 38
C00012528 External link 512 Cuprenene
/ 2-Cuprenene
/ Cuprenene 2
/ Cuprenene III
No. 451 No. 38
C00002608 External link 512 Hinokinin
/ Hinoquinin
/ (-)-Hinokinin
/ (-)-Hinoquinin
CHEMBL180970
CHEMBL182073
CHEMBL242011
C475934
2 / 1 / 1 No. 629 No. 21
C00012018 External link 512 (-)-beta-Elemenal
/ (-)-Elema-1,3,11(13)-trien-12-al
No. 1400
C00010843 External link 512 Macropone
CHEMBL353354
1 / 4 / 2 No. 3751 No. 35
C00012048 External link 512 Occidiol
/ Occidenol
No. 4166
C00021879 External link 512 Mayurone
No. 4724
C00011009 External link 512 beta-Dolabrin
C410956
No. 4728
C00010311 External link 512 (S)-Citronellic acid
/ (S)-3,7-Dimethyl-6-octenoic acid
No. 8694

Human Protein / Gene in interactions

14 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002597 C00002608 C00007208 0 / 1
Q99700 Ataxin-2 Unclassified protein C00002597 C00007208 1 / 1
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00002597 C00007208 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00002597 C00007208 1 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00002597 C00007208 2 / 0
O75496 Geminin Unclassified protein C00002597 C00007208 0 / 0
P14679 Tyrosinase Oxidoreductase C00010843 4 / 2
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00002597 0 / 0
P08253 72 kDa type IV collagenase M10A C00009089 1 / 3
P02545 Prelamin-A/C Unclassified protein C00007208 11 / 10
Q9UNA4 DNA polymerase iota Enzyme C00007208 0 / 0
P14780 Matrix metalloproteinase-9 M10A C00009089 2 / 2
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00002608 1 / 0
Q06710 Paired box protein Pax-8 Unclassified protein C00007208 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (24)

OMIM preferred title UniProt
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#114500 Colorectal cancer; crc P84022
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#137800 Glioma susceptibility 1; glm1 O75874
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#218700 Hypothyroidism, congenital, nongoitrous, 2; chng2 Q06710
#603932 Intervertebral disc disease; idd P14780
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#259600 Multicentric osteolysis, nodulosis, and arthropathy; mona P08253
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#275210 Restrictive dermopathy, lethal P02545
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#183090 Spinocerebellar ataxia 2; sca2 Q99700

KEGG DISEASE (20)

KEGG name UniProt
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00025 Penile cancer P08253 (related)
P14780 (related)
H00028 Choriocarcinoma P08253 (related)
H00472 Torg-Winchester syndrome P08253 (related)
H00036 Osteosarcoma P08684 (marker)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00038 Malignant melanoma P14679 (marker)
H00479 Metaphyseal dysplasias P14780 (related)
H00032 Thyroid cancer Q06710 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) Q06710 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)