Gastrodia elata

• Index
• Plant Species
• Metabolite list (9)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Gastrodia elata
Genus	Gastrodia
Family	Orchidaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Gastrodia elata
Linked NCBI taxonomy ID	91201
Linked level	species

Family

Family in NCBI taxonomy	Orchidaceae
ID	4747

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	Liliopsida
ID	4447

Metabolite list (9)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00029516	Gastrodin / (-)-Gastrodin / 4-(beta-D-Glucopyranosyloxy) benzyl alcohol	CHEMBL274739	C045345	2 / 2 / 2	0 / 2	No. 45	No. 72
C00029830	Bis(4-Hydroxybenzyl) ether / 4,4'-Dihydroxydibenzyl ether					No. 242	No. 26
C00029533	Gastrodigenin / 4-Methylolphenol / p-Hydroxybenzyl alcohol / 4-Hydroxybenzyl alcohol	CHEMBL202132	C018966	6 / 3 / 4	0 / 2	No. 936	No. 6
C00007444	Adenosine	CHEMBL477 CHEMBL11909 CHEMBL20247 CHEMBL1090 CHEMBL91573 CHEMBL145188 CHEMBL1236872 CHEMBL1413677 CHEMBL2051971	D000241	61 / 89 / 68	33 / 35	No. 1060
C00002656	Hydroquinone / 1,4-Benzenediol	CHEMBL537	C031927	55 / 48 / 51	156 / 14	No. 1590	No. 82
C00039932	Parishin					No. 1768
C00002657	p-Formylphenol / 4-Hydroxybenzaldehyde / p-Hydroxybenzaldehyde	CHEMBL14193	C011483	3 / 2 / 2		No. 2076
C00019674	Uridine	CHEMBL68846 CHEMBL100259 CHEMBL265701 CHEMBL608294 CHEMBL609651 CHEMBL1092065 CHEMBL2093066	D014529	5 / 0 / 3	7 / 15	No. 2366
C00040564	Trimethyl citrate	CHEMBL455514				No. 6795

Human Protein / Gene in interactions

114 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P80404	4-aminobutyrate aminotransferase, mitochondrial	Transferase	C00002657 C00029516 C00029533	1 / 1
P51649	Succinate-semialdehyde dehydrogenase, mitochondrial	Oxidoreductase	C00002657 C00029516 C00029533	1 / 1
O75496	Geminin	Unclassified protein	C00002656 C00007444 C00019674	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00002656 C00007444	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00002656 C00007444	4 / 3
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00002656 C00007444	0 / 1
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00002656 C00007444	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00002656 C00007444	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00002656 C00019674	0 / 3
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00002656 C00007444	2 / 0
O00255	Menin	Unclassified protein	C00002656 C00007444	2 / 5
P39748	Flap endonuclease 1	Enzyme	C00002656 C00007444	0 / 0
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00002656 C00007444	0 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00002656 C00007444	1 / 2
P02545	Prelamin-A/C	Unclassified protein	C00002656 C00007444	11 / 10
Q6DHV7	Adenosine deaminase-like protein	Enzyme	C00007444	0 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00002656	0 / 0
P04406	Glyceraldehyde-3-phosphate dehydrogenase	Enzyme	C00007444	0 / 0
Q8TD43	Transient receptor potential cation channel subfamily M member 4	Unclassified protein	C00007444	1 / 1
P00519	Tyrosine-protein kinase ABL1	Abl	C00029533	1 / 2
P00813	Adenosine deaminase	Hydrolase	C00007444	1 / 1
P12268	Inosine-5'-monophosphate dehydrogenase 2	Oxidoreductase	C00007444	0 / 0
P16473	Thyrotropin receptor	Glycohormone receptor	C00007444	3 / 2
P10828	Thyroid hormone receptor beta	NR1A2	C00002656	3 / 1
P19793	Retinoic acid receptor RXR-alpha	NR2B1	C00002656	0 / 0
P29275	Adenosine receptor A2b	Adenosine receptor	C00007444	0 / 0
P43166	Carbonic anhydrase 7	Lyase	C00002656	0 / 0
P00918	Carbonic anhydrase 2	Lyase	C00002656	1 / 2
P04183	Thymidine kinase, cytosolic	Enzyme	C00007444	0 / 1
P06241	Tyrosine-protein kinase Fyn	Src	C00029533	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00007444	0 / 1
P54132	Bloom syndrome protein	Enzyme	C00002656	1 / 2
Q9HBX9	Relaxin receptor 1	Relaxin receptor	C00007444	0 / 0
Q9HAW7	UDP-glucuronosyltransferase 1-7	Enzyme	C00002656	0 / 0
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00007444	1 / 8
P47901	Vasopressin V1b receptor	Vasopressin and oxytocin receptor	C00007444	0 / 0
P29274	Adenosine receptor A2a	Adenosine receptor	C00007444	0 / 0
P23280	Carbonic anhydrase 6	Lyase	C00002656	0 / 0
Q9ULX7	Carbonic anhydrase 14	Lyase	C00002656	0 / 0
P27708	CAD protein	Enzyme	C00019674	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00002656	0 / 0
P68871	Hemoglobin subunit beta	Secreted protein	C00002656	4 / 4
O43570	Carbonic anhydrase 12	Lyase	C00002656	1 / 2
P35218	Carbonic anhydrase 5A, mitochondrial	Lyase	C00002656	0 / 0
P14902	Indoleamine 2,3-dioxygenase 1	Enzyme	C00002657	0 / 0
Q9Y2D0	Carbonic anhydrase 5B, mitochondrial	Lyase	C00002656	0 / 0
P42858	Huntingtin	Unclassified protein	C00007444	1 / 1
P33765	Adenosine receptor A3	Adenosine receptor	C00007444	0 / 0
P51151	Ras-related protein Rab-9A	Unclassified protein	C00002656	0 / 0
Q9HA47	Uridine-cytidine kinase 1	Enzyme	C00019674	0 / 0
P10145	Interleukin-8	Secreted protein	C00002656	0 / 0
P00915	Carbonic anhydrase 1	Lyase	C00002656	0 / 0
P27487	Dipeptidyl peptidase 4	S9B	C00007444	0 / 1
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00007444	7 / 3
P42226	Signal transducer and activator of transcription 6	Unclassified protein	C00007444	0 / 0
P46108	Adapter molecule crk	Unclassified protein	C00029533	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00002656	0 / 0
P04150	Glucocorticoid receptor	NR3C1	C00002656	0 / 1
P06213	Insulin receptor	TK tyrosine-protein kinase INSR subfamily	C00007444	5 / 4
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00007444	2 / 2
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00007444	5 / 9
P09619	Platelet-derived growth factor receptor beta	Pdgfr	C00007444	5 / 1
P55263	Adenosine kinase	Enzyme	C00007444	1 / 0
Q96RI1	Bile acid receptor	NR1H4	C00002656	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00007444	0 / 0
P62993	Growth factor receptor-bound protein 2	Other cytosolic protein	C00029533	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00007444	0 / 0
Q16790	Carbonic anhydrase 9	Lyase	C00002656	0 / 1
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00002656	3 / 3
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00002656	2 / 2
O15118	Niemann-Pick C1 protein	Unclassified protein	C00002656	1 / 1
Q01453	Peripheral myelin protein 22	Unclassified protein	C00002656	5 / 2
Q8WXD0	Relaxin receptor 2	Relaxin receptor	C00007444	1 / 1
P51449	Nuclear receptor ROR-gamma	Nuclear hormone receptor subfamily 1 group F member 3	C00002656	0 / 0
P20839	Inosine-5'-monophosphate dehydrogenase 1	Oxidoreductase	C00007444	2 / 2
P03372	Estrogen receptor	NR3A1	C00002656	1 / 1
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00007444	1 / 0
P05771	Protein kinase C beta type	Alpha	C00007444	0 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00002656	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00007444	1 / 1
Q99700	Ataxin-2	Unclassified protein	C00002656	1 / 1
Q9UNA4	DNA polymerase iota	Enzyme	C00019674	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00007444	0 / 0
Q9HAW8	UDP-glucuronosyltransferase 1-10	Enzyme	C00002656	0 / 0
Q99549	M-phase phosphoprotein 8	Unclassified protein	C00002656	0 / 0
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00002656	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00002656	0 / 0
P10275	Androgen receptor	NR3C4	C00002656	3 / 4
P30542	Adenosine receptor A1	Adenosine receptor	C00007444	0 / 0
P07451	Carbonic anhydrase 3	Lyase	C00002656	0 / 0
P35869	Aryl hydrocarbon receptor	Transcription Factor	C00002656	0 / 0
P22748	Carbonic anhydrase 4	Lyase	C00002656	1 / 1
Q9GZV3	High affinity choline transporter 1	Choline Na-symporter	C00007444	1 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00002656	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00002656	0 / 0
P40225	Thrombopoietin	Unclassified protein	C00002656	1 / 1
Q16637	Survival motor neuron protein	Unclassified protein	C00007444	4 / 1
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00007444	1 / 0
P23526	Adenosylhomocysteinase	Enzyme	C00007444	1 / 1
P42345	Serine/threonine-protein kinase mTOR	Enzyme	C00002656	0 / 0
P11362	Fibroblast growth factor receptor 1	Fgfr	C00007444	4 / 5
P22455	Fibroblast growth factor receptor 4	Fgfr	C00007444	0 / 0
P22607	Fibroblast growth factor receptor 3	Fgfr	C00007444	14 / 6
P21802	Fibroblast growth factor receptor 2	TK tyrosine-protein kinase TLK subfamily	C00007444	9 / 3
P07205	Phosphoglycerate kinase 2	Enzyme	C00007444	0 / 0
P00558	Phosphoglycerate kinase 1	Enzyme	C00007444	1 / 1
Q9UBF8	Phosphatidylinositol 4-kinase beta	Enzyme	C00007444	0 / 0
Q8TCG2	Phosphatidylinositol 4-kinase type 2-beta	Enzyme	C00007444	0 / 0
Q9BTU6	Phosphatidylinositol 4-kinase type 2-alpha	Enzyme	C00007444	0 / 0
P42356	Phosphatidylinositol 4-kinase alpha	Enzyme	C00007444	0 / 0
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00007444	0 / 1
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00007444	1 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00007444	0 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00002656	0 / 0

180 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
4609	MYC, MRTL, MYCC, bHLHe39, c-Myc	v-myc avian myelocytomatosis viral oncogene homolog	C00002656 C00007444 C00019674
330	BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2	baculoviral IAP repeat containing 3	C00002656 C00007444
2030	SLC29A1, ENT1	solute carrier family 29 (equilibrative nucleoside transporter), member 1	C00007444 C00019674
9153	SLC28A2, CNT2, HCNT2, HsT17153, SPNT1	solute carrier family 28 (concentrative nucleoside transporter), member 2	C00007444 C00019674
9154	SLC28A1, CNT1, HCNT1	solute carrier family 28 (concentrative nucleoside transporter), member 1	C00007444 C00019674
356	FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6	Fas ligand (TNF superfamily, member 6)	C00007444 C00019674
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00002656 C00007444
3177	SLC29A2, DER12, ENT2, HNP36	solute carrier family 29 (equilibrative nucleoside transporter), member 2	C00007444 C00019674
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00002656 C00007444
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00002656 C00007444
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00002656 C00007444
2993	GYPA, CD235a, GPA, GPErik, GPSAT, HGpMiV, HGpMiXI, HGpSta(C), MN, MNS, PAS-2	glycophorin A (MNS blood group)	C00002656 C00019674
8772	FADD, MORT1	Fas (TNFRSF6)-associated via death domain	C00002656 C00007444
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00002656 C00007444
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00002656 C00007444
8614	STC2, STC-2, STCRP	stanniocalcin 2	C00002656
6356	CCL11, SCYA11	chemokine (C-C motif) ligand 11	C00002656
6347	CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF	chemokine (C-C motif) ligand 2	C00002656
6348	CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3	chemokine (C-C motif) ligand 3	C00002656
6351	CCL4, ACT2, AT744.1, G-26, HC21, LAG-1, LAG1, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4	chemokine (C-C motif) ligand 4	C00002656
6352	CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP	chemokine (C-C motif) ligand 5	C00002656
9134	CCNE2, CYCE2	cyclin E2	C00002656
899	CCNF, FBX1, FBXO1	cyclin F	C00002656
942	CD86, B7-2, B7.2, B70, CD28LG2, LAB72	CD86 molecule	C00002656
157313	CDCA2, Repo-Man	cell division cycle associated 2	C00002656
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00002656
1058	CENPA, CENP-A, CenH3	centromere protein A	C00002656
1277	COL1A1, OI4	collagen, type I, alpha 1	C00002656
1282	COL4A1, HANAC, ICH, POREN1, arresten	collagen, type IV, alpha 1	C00002656
1436	CSF1R, C-FMS, CD115, CSF-1R, CSFR, FIM2, FMS, HDLS, M-CSF-R	colony stimulating factor 1 receptor (EC:2.7.10.1)	C00002656
1437	CSF2, GMCSF	colony stimulating factor 2 (granulocyte-macrophage)	C00002656
6387	CXCL12, IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1, SDF1A, SDF1B	chemokine (C-X-C motif) ligand 12	C00002656
54205	CYCS, CYC, HCS, THC4	cytochrome c, somatic	C00002656
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00002656
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00002656
24300			C00002656
1565	CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1	cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1)	C00002656
1571	CYP2E1, CPE1, CYP2E, P450-J, P450C2E	cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7)	C00002656
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00002656
1577	CYP3A5, CP35, CYPIIIA5, P450PCN3, PCN3	cytochrome P450, family 3, subfamily A, polypeptide 5 (EC:1.14.14.1)	C00002656
3491	CYR61, CCN1, GIG1, IGFBP10	cysteine-rich, angiogenic inducer, 61	C00002656
1611	DAP	death-associated protein	C00002656
1649	DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153	DNA-damage-inducible transcript 3	C00002656
54541	DDIT4, Dig2, REDD-1, REDD1	DNA-damage-inducible transcript 4	C00002656
22943	DKK1, DKK-1, SK	dickkopf WNT signaling pathway inhibitor 1	C00002656
3301	DNAJA1, DJ-2, DjA1, HDJ2, HSDJ, HSJ2, HSPF4, NEDD7, hDJ-2	DnaJ (Hsp40) homolog, subfamily A, member 1	C00002656
3337	DNAJB1, HSPF1, Hdj1, Hsp40, RSPH16B, Sis1	DnaJ (Hsp40) homolog, subfamily B, member 1	C00002656
1786	DNMT1, ADCADN, AIM, CXXC9, DNMT, HSN1E, MCMT	DNA (cytosine-5-)-methyltransferase 1 (EC:2.1.1.37)	C00002656
1788	DNMT3A, DNMT3A2, M.HsaIIIA	DNA (cytosine-5-)-methyltransferase 3 alpha (EC:2.1.1.37)	C00002656
1789	DNMT3B, ICF, ICF1, M.HsaIIIB	DNA (cytosine-5-)-methyltransferase 3 beta (EC:2.1.1.37)	C00002656
1999	ELF3, EPR-1, ERT, ESE-1, ESX	E74-like factor 3 (ets domain transcription factor, epithelial-specific )	C00002656
840	CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3	caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60)	C00002656
81610	FAM83D, C20orf129, CHICA, dJ616B8.3	family with sequence similarity 83, member D	C00002656
26271	FBXO5, EMI1, FBX5, Fbxo31	F-box protein 5	C00002656
2335	FN1, CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF	fibronectin 1	C00002656
2353	FOS, AP-1, C-FOS, p55	FBJ murine osteosarcoma viral oncogene homolog	C00002656
2495	FTH1, FHC, FTH, FTHL6, PIG15, PLIF	ferritin, heavy polypeptide 1 (EC:1.16.3.1)	C00002656
1647	GADD45A, DDIT1, GADD45	growth arrest and DNA-damage-inducible, alpha	C00002656
2623	GATA1, ERYF1, GATA-1, GF-1, GF1, NF-E1, NFE1, XLANP, XLTDA, XLTT	GATA binding protein 1 (globin transcription factor 1)	C00002656
2624	GATA2, DCML, MONOMAC, NFE1B	GATA binding protein 2	C00002656
2730	GCLM, GLCLR	glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2)	C00002656
9518	GDF15, GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB	growth differentiation factor 15	C00002656
2937	GSS, GSHS	glutathione synthetase (EC:6.3.2.3)	C00002656
2944	GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1	glutathione S-transferase mu 1 (EC:2.5.1.18)	C00002656
839	CASP6, MCH2	caspase 6, apoptosis-related cysteine peptidase (EC:3.4.22.59)	C00002656
3014	H2AFX, H2A.X, H2A/X, H2AX	H2A histone family, member X	C00002656
3043	HBB, CD113t-C, beta-globin	hemoglobin, beta	C00002656
3009	HIST1H1B, H1, H1.5, H1B, H1F5, H1s-3	histone cluster 1, H1b	C00002656
3007	HIST1H1D, H1.3, H1D, H1F3, H1s-2	histone cluster 1, H1d	C00002656
3008	HIST1H1E, H1.4, H1E, H1F4, H1s-4, dJ221C16.5	histone cluster 1, H1e	C00002656
85235	HIST1H2AH, H2A/S, H2AFALii, H2AH, dJ86C11.1	histone cluster 1, H2ah	C00002656
8329	HIST1H2AI, H2A/c, H2AFC	histone cluster 1, H2ai	C00002656
8331	HIST1H2AJ, H2A/E, H2AFE, dJ160A22.4	histone cluster 1, H2aj	C00002656
8358	HIST1H3B, H3/l, H3FL	histone cluster 1, H3b	C00002656
8352	HIST1H3C, H3.1, H3/c, H3FC	histone cluster 1, H3c	C00002656
8359	HIST1H4A, H4FA	histone cluster 1, H4a	C00002656
8366	HIST1H4B, H4/I, H4FI	histone cluster 1, H4b	C00002656
8364	HIST1H4C, H4/g, H4FG, dJ221C16.1	histone cluster 1, H4c	C00002656
8367	HIST1H4E, H4/j, H4FJ	histone cluster 1, H4e	C00002656
8361	HIST1H4F, H4, H4/c, H4FC	histone cluster 1, H4f	C00002656
8365	HIST1H4H, H4/h, H4FH	histone cluster 1, H4h	C00002656
8362	HIST1H4K, H4/d, H4F2iii, H4FD, dJ160A22.1	histone cluster 1, H4k	C00002656
8337	HIST2H2AA3, H2A, H2A.2, H2A/O, H2A/q, H2AFO, H2a-615, HIST2H2AA	histone cluster 2, H2aa3	C00002656
317772	HIST2H2AB, H2AB	histone cluster 2, H2ab	C00002656
8338	HIST2H2AC, H2A, H2A-GL101, H2A/q, H2AFQ	histone cluster 2, H2ac	C00002656
8370	HIST2H4A, FO108, H4, H4/n, H4F2, H4FN, HIST2H4	histone cluster 2, H4a	C00002656
55355	HJURP, FAKTS, URLC9, hFLEG1	Holliday junction recognition protein	C00002656
3145	HMBS, PBG-D, PBGD, PORC, UPS	hydroxymethylbilane synthase (EC:2.5.1.61)	C00002656
3148	HMGB2, HMG2	high mobility group box 2	C00002656
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00002656
3306	HSPA2, HSP70-2, HSP70-3	heat shock 70kDa protein 2	C00002656
219844	HYLS1, HLS	hydrolethalus syndrome 1	C00002656
3586	IL10, CSIF, GVHDS, IL-10, IL10A, TGIF	interleukin 10	C00002656
3558	IL2, IL-2, TCGF, lymphokine	interleukin 2	C00002656
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00002656
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00002656
3688	ITGB1, CD29, FNRB, GPIIA, MDF2, MSK12, VLA-BETA, VLAB	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	C00002656
3689	ITGB2, CD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	C00002656
182	JAG1, AGS, AHD, AWS, CD339, HJ1, JAGL1	jagged 1	C00002656
81930	KIF18A, MS-KIF18A	kinesin family member 18A	C00002656
4254	KITLG, FPH2, KL-1, Kitl, MGF, SCF, SF, SHEP7	KIT ligand	C00002656
3910	LAMA4, CMD1JJ, LAMA3, LAMA4*-1	laminin, alpha 4	C00002656
11061	LECT1, BRICD3, CHM-I, CHM1, MYETS1	leukocyte cell derived chemotaxin 1	C00002656
4000	LMNA, CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, LDP1, LFP, LGMD1B, LMN1, LMNC, LMNL1, PRO1	lamin A/C	C00002656
7832	BTG2, PC3, TIS21	BTG family, member 2	C00002656
79866	BORA, C13orf34	bora, aurora kinase A activator	C00002656
8932	MBD2, DMTase, NY-CO-41	methyl-CpG binding domain protein 2	C00002656
4257	MGST1, GST12, MGST, MGST-I	microsomal glutathione S-transferase 1 (EC:2.5.1.18)	C00002656
4323	MMP14, MMP-14, MMP-X1, MT-MMP, MT-MMP_1, MT1-MMP, MT1MMP, MTMMP1, WNCHRS	matrix metallopeptidase 14 (membrane-inserted) (EC:3.4.24.80)	C00002656
4324	MMP15, MT2-MMP, MTMMP2, SMCP-2	matrix metallopeptidase 15 (membrane-inserted) (EC:3.4.24.-)	C00002656
4313	MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24)	C00002656
4314	MMP3, CHDS6, MMP-3, SL-1, STMY, STMY1, STR1	matrix metallopeptidase 3 (stromelysin 1, progelatinase) (EC:3.4.24.17)	C00002656
4318	MMP9, CLG4B, GELB, MANDP2, MMP-9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35)	C00002656
4352	MPL, C-MPL, CD110, MPLV, THCYT2, TPOR	myeloproliferative leukemia virus oncogene	C00002656
4353	MPO	myeloperoxidase (EC:1.11.2.2)	C00002656
664	BNIP3, NIP3	BCL2/adenovirus E1B 19kDa interacting protein 3	C00002656
4778	NFE2, NF-E2, p45	nuclear factor, erythroid 2	C00002656
4780	NFE2L2, NRF2	nuclear factor, erythroid 2-like 2	C00002656
1728	NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1	NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2)	C00002656
5036	PA2G4, EBP1, HG4-1, p38-2G4	proliferation-associated 2G4, 38kDa	C00002656
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00002656
25796	PGLS, 6PGL	6-phosphogluconolactonase (EC:3.1.1.31)	C00002656
5429	POLH, RAD30, RAD30A, XP-V, XPV	polymerase (DNA directed), eta (EC:2.7.7.7)	C00002656
8493	PPM1D, PP2C-DELTA, WIP1	protein phosphatase, Mg2+/Mn2+ dependent, 1D (EC:3.1.3.16)	C00002656
5052	PRDX1, MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2	peroxiredoxin 1 (EC:1.11.1.15)	C00002656
5591	PRKDC, DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350	protein kinase, DNA-activated, catalytic polypeptide (EC:2.7.11.1)	C00002656
84722	PSRC1, DDA3, FP3214	proline/serine-rich coiled-coil 1	C00002656
9401	RECQL4, RECQ4	RecQ protein-like 4 (EC:3.6.4.12)	C00002656
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00002656
860	RUNX2, AML3, CBF-alpha-1, CBFA1, CCD, CCD1, CLCD, OSF-2, OSF2, PEA2aA, PEBP2aA	runt-related transcription factor 2	C00002656
27244	SESN1, PA26, SEST1	sestrin 1	C00002656
83667	SESN2, HI95, SES2, SEST2	sestrin 2	C00002656
6647	SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer	superoxide dismutase 1, soluble (EC:1.15.1.1)	C00002656
6648	SOD2, IPOB, MNSOD, MVCD6	superoxide dismutase 2, mitochondrial (EC:1.15.1.1)	C00002656
6688	SPI1, OF, PU.1, SFPI1, SPI-1, SPI-A	spleen focus forming virus (SFFV) proviral integration oncogene	C00002656
847	CAT	catalase (EC:1.11.1.6)	C00002656
7037	TFRC, CD71, T9, TFR, TFR1, TR, TRFR, p90	transferrin receptor	C00002656
7077	TIMP2, CSC-21K, DDC8	TIMP metallopeptidase inhibitor 2	C00002656
25976	TIPARP, ARTD14, PARP7, pART14	TCDD-inducible poly(ADP-ribose) polymerase (EC:2.4.2.30)	C00002656
64782	AEN, ISG20L1, pp12744	apoptosis enhancing nuclease	C00002656
8795	TNFRSF10B, CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9	tumor necrosis factor receptor superfamily, member 10b	C00002656
8793	TNFRSF10D, CD264, DCR2, TRAIL-R4, TRAILR4, TRUNDD	tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain	C00002656
8718	TNFRSF25, APO-3, DDR3, DR3, LARD, TNFRSF12, TR3, TRAMP, WSL-1, WSL-LR	tumor necrosis factor receptor superfamily, member 25	C00002656
3604	TNFRSF9, 4-1BB, CD137, CDw137, ILA	tumor necrosis factor receptor superfamily, member 9	C00002656
8742	TNFSF12, APO3L, DR3LG, TWEAK	tumor necrosis factor (ligand) superfamily, member 12	C00002656
7153	TOP2A, TOP2, TP2A	topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3)	C00002656
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00002656
94241	TP53INP1, SIP, TP53DINP1, TP53INP1A, TP53INP1B, Teap, p53DINP1	tumor protein p53 inducible nuclear protein 1	C00002656
8717	TRADD, Hs.89862	TNFRSF1A-associated via death domain	C00002656
9618	TRAF4, CART1, MLN62, RNF83	TNF receptor-associated factor 4	C00002656
286827	TRIM59, MRF1, RNF104, TRIM57, TSBF1	tripartite motif containing 59	C00002656
8989	TRPA1, ANKTM1, FEPS	transient receptor potential cation channel, subfamily A, member 1	C00002656
7295	TXN, TRDX, TRX, TRX1	thioredoxin	C00002656
7296	TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR	thioredoxin reductase 1 (EC:1.8.1.9)	C00002656
7474	WNT5A, hWNT5A	wingless-type MMTV integration site family, member 5A	C00002656
7486	WRN, RECQ3, RECQL2, RECQL3	Werner syndrome, RecQ helicase-like (EC:3.6.4.12)	C00002656
100	ADA	adenosine deaminase (EC:3.5.4.4)	C00007444
134	ADORA1, RDC7	adenosine A1 receptor	C00007444
135	ADORA2A, A2aR, ADORA2, RDC8	adenosine A2a receptor	C00007444
140	ADORA3, A3AR, AD026, bA552M11.5	adenosine A3 receptor	C00007444
248	ALPI, IAP	alkaline phosphatase, intestinal (EC:3.1.3.1)	C00007444
581	BAX, BCL2L4	BCL2-associated X protein	C00007444
598	BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS	BCL2-like 1	C00007444
329	BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1	baculoviral IAP repeat containing 2	C00007444
929	CD14	CD14 molecule	C00007444
8837	CFLAR, CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS	CASP8 and FADD-like apoptosis regulator	C00007444
1080	CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49)	C00007444
56616	DIABLO, DFNA64, SMAC	diablo, IAP-binding mitochondrial protein	C00007444
1803	DPP4, ADABP, ADCP2, CD26, DPPIV, TP103	dipeptidyl-peptidase 4 (EC:3.4.14.5)	C00007444
27113	BBC3, JFY-1, JFY1, PUMA	BCL2 binding component 3	C00002656
3091	HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	C00007444
23643	LY96, ESOP-1, MD-2, MD2, ly-96	lymphocyte antigen 96	C00007444
10891	PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	C00007444
572	BAD, BBC2, BCL2L8	BCL2-associated agonist of cell death	C00002656
468	ATF4, CREB-2, CREB2, TAXREB67, TXREB	activating transcription factor 4	C00002656
396	ARHGDIA, GDIA1, NPHS8, RHOGDI, RHOGDI-1	Rho GDP dissociation inhibitor (GDI) alpha	C00002656
217	ALDH2, ALDH-E2, ALDHI, ALDM	aldehyde dehydrogenase 2 family (mitochondrial) (EC:1.2.1.3)	C00002656
55315	SLC29A3, ENT3, HCLAP, HJCD, PHID	solute carrier family 29 (equilibrative nucleoside transporter), member 3	C00007444
7099	TLR4, ARMD10, CD284, TLR-4, TOLL	toll-like receptor 4	C00007444
7422	VEGFA, MVCD1, VEGF, VPF	vascular endothelial growth factor A	C00007444

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