KEGG   COMPOUND: C00025Help
Entry
C00025                      Compound                               

Name
L-Glutamate;
L-Glutamic acid;
L-Glutaminic acid;
Glutamate
Formula
C5H9NO4
Exact mass
147.0532
Mol weight
147.1293
Structure
Mol fileKCF fileDB search
Remark
Same as: D00007
Reaction
R00021 R00093 R00114 R00239 R00241 R00243 R00245 R00248
R00250 R00251 R00253 R00254 R00256 R00257 R00258 R00259
R00260 R00261 R00262 R00263 R00355 R00372 R00411 R00457
R00494 R00525 R00573 R00575 R00578 R00609 R00667 R00668
R00684 R00694 R00707 R00708 R00734 R00768 R00894 R00895
R00908 R00942 R00986 R01072 R01090 R01155 R01161 R01214
R01231 R01339 R01585 R01586 R01648 R01654 R01684 R01716
R01939 R01956 R02040 R02077 R02199 R02237 R02274 R02282
R02283 R02285 R02287 R02313 R02315 R02433 R02619 R02700
R02772 R02773 R02929 R02930 R03053 R03120 R03189 R03207
 » show all
Pathway
map00220  Arginine biosynthesis
map00250  Alanine, aspartate and glutamate metabolism
map00330  Arginine and proline metabolism
map00332  Carbapenem biosynthesis
map00340  Histidine metabolism
map00430  Taurine and hypotaurine metabolism
map00471  D-Glutamine and D-glutamate metabolism
map00480  Glutathione metabolism
map00524  Neomycin, kanamycin and gentamicin biosynthesis
map00630  Glyoxylate and dicarboxylate metabolism
map00650  Butanoate metabolism
map00660  C5-Branched dibasic acid metabolism
map00860  Porphyrin and chlorophyll metabolism
map00910  Nitrogen metabolism
map00970  Aminoacyl-tRNA biosynthesis
map01060  Biosynthesis of plant secondary metabolites
map01064  Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01120  Microbial metabolism in diverse environments
map01130  Biosynthesis of antibiotics
map01200  Carbon metabolism
map01210  2-Oxocarboxylic acid metabolism
map01230  Biosynthesis of amino acids
map02010  ABC transporters
map02020  Two-component system
map04068  FoxO signaling pathway
map04072  Phospholipase D signaling pathway
map04080  Neuroactive ligand-receptor interaction
map04216  Ferroptosis
map04540  Gap junction
map04713  Circadian entrainment
map04720  Long-term potentiation
map04721  Synaptic vesicle cycle
map04723  Retrograde endocannabinoid signaling
map04724  Glutamatergic synapse
map04727  GABAergic synapse
map04730  Long-term depression
map04742  Taste transduction
map04964  Proximal tubule bicarbonate reclamation
map04974  Protein digestion and absorption
map05014  Amyotrophic lateral sclerosis (ALS)
map05016  Huntington disease
map05030  Cocaine addiction
map05031  Amphetamine addiction
map05033  Nicotine addiction
map05034  Alcoholism
map05230  Central carbon metabolism in cancer
Module
M00015  Proline biosynthesis, glutamate => proline
M00027  GABA (gamma-Aminobutyrate) shunt
M00028  Ornithine biosynthesis, glutamate => ornithine
M00045  Histidine degradation, histidine => N-formiminoglutamate => glutamate
M00118  Glutathione biosynthesis, glutamate => glutathione
M00121  Heme biosynthesis, glutamate => heme
M00532  Photorespiration
M00740  Methylaspartate cycle
M00763  Ornithine biosynthesis, mediated by LysW, glutamate => ornithine
M00845  Arginine biosynthesis, glutamate => acetylcitrulline => arginine
M00846  Siroheme biosynthesis, glutamate => siroheme
Enzyme
1.2.1.88        1.4.1.2         1.4.1.3         1.4.1.4         
1.4.1.13        1.4.1.14        1.4.3.11        1.4.7.1         
1.5.1.9         1.5.1.10        1.5.3.18        1.5.99.5        
2.1.1.21        2.1.2.5         2.3.1.1         2.3.1.14        
2.3.1.35        2.3.2.2         2.3.2.-         2.4.2.14        
2.4.2.-         2.5.1.140       2.6.1.1         2.6.1.2         
2.6.1.3         2.6.1.4         2.6.1.5         2.6.1.6         
2.6.1.7         2.6.1.8         2.6.1.9         2.6.1.11        
2.6.1.13        2.6.1.16        2.6.1.17        2.6.1.19        
2.6.1.22        2.6.1.23        2.6.1.24        2.6.1.26        
2.6.1.27        2.6.1.29        2.6.1.33        2.6.1.34        
2.6.1.36        2.6.1.38        2.6.1.39        2.6.1.40        
2.6.1.42        2.6.1.44        2.6.1.48        2.6.1.49        
2.6.1.52        2.6.1.55        2.6.1.57        2.6.1.59        
2.6.1.65        2.6.1.67        2.6.1.72        2.6.1.75        
2.6.1.76        2.6.1.79        2.6.1.80        2.6.1.81        
2.6.1.82        2.6.1.83        2.6.1.85        2.6.1.86        
2.6.1.87        2.6.1.89        2.6.1.90        2.6.1.92        
2.6.1.93        2.6.1.94        2.6.1.95        2.6.1.98        
2.6.1.102       2.6.1.103       2.6.1.104       2.6.1.106       
2.6.1.107       2.6.1.109       2.6.1.110       2.6.1.111       
2.6.1.114       2.6.1.-         2.7.2.11        2.7.2.13        
3.4.17.21       3.4.19.9        3.4.19.13       3.4.19.14       
3.4.19.16       3.5.1.2         3.5.1.38        3.5.1.55        
3.5.1.65        3.5.1.68        3.5.1.87        3.5.1.94        
3.5.1.96        3.5.1.118       3.5.1.123       3.5.2.9         
3.5.3.8         4.1.1.15        4.1.3.27        4.1.3.-         
4.2.1.168       4.3.3.6         5.1.1.3         5.4.3.9         
5.4.99.1        6.1.1.17        6.1.1.24        6.2.1.39        
6.3.1.2         6.3.1.6         6.3.1.11        6.3.1.17        
6.3.1.18        6.3.2.2         6.3.2.12        6.3.2.17        
6.3.2.18        6.3.2.31        6.3.2.32        6.3.2.33        
6.3.2.34        6.3.2.41        6.3.2.42        6.3.2.-         
6.3.4.2         6.3.4.12        6.3.4.24        6.3.5.1         
6.3.5.2         6.3.5.3         6.3.5.4         6.3.5.5         
6.3.5.6         6.3.5.7         6.3.5.9         6.3.5.10        
6.3.5.11        6.3.5.12        6.3.5.-
 » show all
Brite
Compounds with biological roles [BR:br08001]
 Peptides
  Amino acids
   Common amino acids
    C00025  Glutamic acid (Glu)
 Hormones and transmitters
  Neurotransmitters
   Amino acids
    C00025  Glutamate
Risk category of Japanese OTC drugs [BR:br08312]
 Third-class OTC drugs
  Inorganic and organic chemicals
   Glutamic acid
    D00007  Glutamic acid (USP)
Pharmaceutical additives in Japan [BR:br08316]
 Buffering agent
  D00007  [003613] L-Glutamic acid
 Flavoring substance
  D00007  [003613] L-Glutamic acid
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00007  L-Glutamic acid
BRITE hierarchy
Other DBs
CAS: 56-86-0
PubChem: 3327
ChEBI: 16015
ChEMBL: CHEMBL575060
KNApSAcK: C00001358
PDB-CCD: GGL[PDBj] GLU[PDBj]
3DMET: B00007
NIKKAJI: J9.171E
KCF data Show

ATOM        10
            1   C1c C    23.8372  -17.4608
            2   C1b C    25.0252  -16.7233
            3   C6a C    22.6023  -16.7994
            4   N1a N    23.8781  -18.8595
            5   C1b C    26.2601  -17.3788
            6   O6a O    21.4434  -17.5954
            7   O6a O    22.6198  -15.4007
            8   C6a C    27.4482  -16.6414
            9   O6a O    28.6830  -17.3028
            10  O6a O    27.4714  -15.2426
BOND        9
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Down
            4     2   5 1
            5     3   6 1
            6     3   7 2
            7     5   8 1
            8     8   9 1
            9     8  10 2

» Japanese version

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