Daphne odora

• Index
• Plant Species
• Metabolite list (14)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Daphne odora
Genus	Daphne
Family	Thymelaeaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Daphne
Linked NCBI taxonomy ID	66679
Linked level	genus

Family

Family in NCBI taxonomy	Thymelaeaceae
ID	39987

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (14)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00013288	Daphnodorin J / (2S)-[3,4,8,9-Tetrahydro-5-hydroxy-2,8-bis(4-hydroxyphenyl)-2H-furo[2,3-h]-1-benzopyran-9-yl](2,4,6-trihydroxyphenyl)methanone					No. 16	No. 19
C00007190	(+)-Pinoresinol	CHEMBL267963 CHEMBL487611 CHEMBL460862	C103298	7 / 5 / 6		No. 38	No. 21
C00013287	Daphnodorin G / [2S-(2alpha,3beta,7aalpha,13abeta)]-3,4,7a,13a-Tetrahydro-3,5,10,12,13a-pentahydroxy-2,7a-bis(4-hydroxyphenyl)-2H,13H-furo[2,3-b:5,4-h']bis[1]benzopyran-13-one					No. 57	No. 18
C00008797	Daphnodorin E	CHEMBL2048507		6 / 5 / 4		No. 57	No. 18
C00014530	Daphnodorin I	CHEMBL1362112		14 / 20 / 16		No. 57	No. 18
C00008795	Daphnodorin C		C055029			No. 57	No. 18
C00008794	Daphnodorin A		C055027			No. 88
C00008796	Daphnodorin D1	CHEMBL1433872		10 / 6 / 4		No. 88
C00008955	Daphnodorin B		C055028			No. 88
C00000606	(-)-Matairesinol	CHEMBL425148	C068935	1 / 0 / 0		No. 223	No. 21
C00000599	(-)-Wikstromol / (-)-Nortrachelogenin	CHEMBL453799 CHEMBL1483370	C020436	3 / 2 / 2		No. 223	No. 21
C00000604	(-)-Secoisolariciresinol	CHEMBL368347	C060283	2 / 1 / 1	1 / 0	No. 282	No. 21
C00000602	(+)-Lariciresinol	CHEMBL518421		2 / 1 / 1		No. 700	No. 21
C00002462	Daphnetin	CHEMBL244948	C039952	40 / 43 / 40		No. 1030	No. 25

Human Protein / Gene in interactions

64 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000602 C00000604 C00002462	1 / 0
P39748	Flap endonuclease 1	Enzyme	C00002462 C00008796 C00014530	0 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00002462 C00008796 C00014530	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00002462 C00008796 C00014530	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000602 C00000604 C00002462	0 / 1
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00000599 C00002462 C00007190	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00002462 C00014530	4 / 3
Q99700	Ataxin-2	Unclassified protein	C00000599 C00008796	1 / 1
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00002462 C00014530	2 / 2
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00000599 C00014530	1 / 1
Q9Y253	DNA polymerase eta	Enzyme	C00002462 C00008796	1 / 1
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00008796 C00014530	2 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00002462 C00008796	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00002462 C00014530	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00002462 C00014530	0 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00008796	0 / 0
P10828	Thyroid hormone receptor beta	NR1A2	C00002462	3 / 1
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00002462	0 / 1
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00002462	1 / 8
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00002462	0 / 0
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00002462	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00002462	0 / 0
P17405	Sphingomyelin phosphodiesterase	Enzyme	C00008796	2 / 2
P04278	Sex hormone-binding globulin	Secreted protein	C00000606	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00002462	11 / 10
P14780	Matrix metalloproteinase-9	M10A	C00008797	2 / 2
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00007190	0 / 0
O75496	Geminin	Unclassified protein	C00002462	0 / 0
P03956	Interstitial collagenase	M10A	C00008797	0 / 1
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00014530	7 / 3
P39900	Macrophage metalloelastase	M10A	C00008797	0 / 0
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00008796	0 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00014530	1 / 2
P83916	Chromobox protein homolog 1	Unclassified protein	C00002462	0 / 0
P11021	78 kDa glucose-regulated protein	Unclassified protein	C00002462	0 / 0
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00007190	5 / 3
P45452	Collagenase 3	M10A	C00008797	1 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00002462	0 / 0
P08253	72 kDa type IV collagenase	M10A	C00008797	1 / 3
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00002462	3 / 3
P06746	DNA polymerase beta	Enzyme	C00002462	0 / 0
Q01453	Peripheral myelin protein 22	Unclassified protein	C00002462	5 / 2
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00007190	0 / 3
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00002462	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00002462	1 / 1
P21728	D(1A) dopamine receptor	Dopamine receptor	C00002462	0 / 0
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00007190	0 / 0
Q6W5P4	Neuropeptide S receptor	Neuropeptide receptor	C00002462	1 / 0
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00002462	1 / 1
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00002462	0 / 0
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00002462	2 / 0
Q99549	M-phase phosphoprotein 8	Unclassified protein	C00002462	0 / 0
Q07869	Peroxisome proliferator-activated receptor alpha	NR1C1	C00007190	0 / 0
P08254	Stromelysin-1	M10A	C00008797	1 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00014530	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00002462	0 / 0
P40225	Thrombopoietin	Unclassified protein	C00002462	1 / 1
Q16637	Survival motor neuron protein	Unclassified protein	C00002462	4 / 1
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00002462	1 / 1
O00255	Menin	Unclassified protein	C00014530	2 / 5
Q13951	Core-binding factor subunit beta	Unclassified protein	C00002462	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00002462	1 / 4
Q9H0H5	Rac GTPase-activating protein 1	Unclassified protein	C00007190	0 / 0
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00014530	1 / 1

1 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
8856	NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR	nuclear receptor subfamily 1, group I, member 2	C00000604

Related Diseases

Diseases related to proteins in ChEMBL interactions