| Organism name | Larix leptolepis | 
|---|---|
| Genus | Larix | 
| Family | Pinaceae | 
| Kingdom | Plantae | 
| Linked NCBI taxonomy name | Larix kaempferi | 
|---|---|
| Linked NCBI taxonomy ID | 54800 | 
| Linked level | species | 
| Family in NCBI taxonomy | Pinaceae | 
|---|---|
| ID | 3318 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae | 
|---|---|
| ID | 33090 | 
| Plant class | Spermatophyta | 
|---|---|
| ID | 58024 | 
| KNApSAcK ID | name | ChEMBL link | CTD link | # of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE | # of genes in CTD interaction / related diseases | KCF-S cluster | phytochemical cluster | figure | 
|---|---|---|---|---|---|---|---|---|
| C00005777   | Syringetin 3-glucoside | CHEMBL1600723 CHEMBL2165404 | 3 / 3 / 7 | No. 2 | No. 15 |   | ||
| C00005850   | Kaempferol 3-(3''-p-coumarylglucoside) | CHEMBL448883 | No. 30 | No. 15 |   | |||
| C00007190   | (+)-Pinoresinol | CHEMBL267963 CHEMBL487611 CHEMBL460862 | C103298 | 7 / 5 / 6 | No. 38 | No. 21 |   | |
| C00000604   | (-)-Secoisolariciresinol | CHEMBL368347 | C060283 | 2 / 1 / 1 | 1 / 0 | No. 282 | No. 21 |   | 
| C00007204   | Isolariciresinol / (+)-Isolariciresinol | CHEMBL399512 CHEMBL1760593 | C060284 | 2 / 1 / 1 | No. 406 |   | ||
| C00002591   | (-)-Cubebin / beta-Cubebin / (-)-beta-Cubebin / (8R,8'R,9S)-Cubebin | CHEMBL182001 CHEMBL399831 | C433065 | 2 / 1 / 1 | 0 / 2 | No. 629 | No. 21 |   | 
| C00000602   | (+)-Lariciresinol | CHEMBL518421 | 2 / 1 / 1 | No. 700 | No. 21 |   | 
| accession | description | class description | KNApSAcK metabolite in interactions | # of diseases (OMIM / KEGG) | 
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000602 C00000604 C00002591 C00007204 | 1 / 0 | 
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000602 C00000604 C00002591 C00007204 | 0 / 1 | 
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00007190 | 0 / 0 | 
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00007190 | 0 / 0 | 
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00005777 | 0 / 0 | 
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00007190 | 5 / 3 | 
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00007190 | 0 / 3 | 
| P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00007190 | 0 / 0 | 
| Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00007190 | 0 / 0 | 
| O00255 | Menin | Unclassified protein | C00005777 | 2 / 5 | 
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00005777 | 1 / 2 | 
| Q9H0H5 | Rac GTPase-activating protein 1 | Unclassified protein | C00007190 | 0 / 0 | 
| gene | gene name | gene description | KNApSAcK metabolite in interactions | 
|---|---|---|---|
| 8856 | NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR | nuclear receptor subfamily 1, group I, member 2 | C00000604 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| %606641 | Body mass index; bmi | P37231 | 
| #609338 | Carotid intimal medial thickness 1 | P37231 | 
| #608902 | Drug metabolism, poor, cyp2d6-related | P10635 | 
| #137800 | Glioma susceptibility 1; glm1 | P37231 | 
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay | Q03164 | 
| #145000 | Hyperparathyroidism 1; hrpt1 | O00255 | 
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 | P37231 | 
| #131100 | Multiple endocrine neoplasia, type i; men1 | O00255 | 
| #601665 | Obesity | P37231 | 
| KEGG | name | UniProt | 
|---|---|---|
| H00033 | Adrenal carcinoma | O00255
                            (related) | 
| H00034 | Carcinoid | O00255
                            (related) | 
| H00045 | Malignant islet cell carcinoma | O00255
                            (related) | 
| H00246 | Primary hyperparathyroidism | O00255
                            (related) | 
| H01102 | Pituitary adenomas | O00255
                            (related) | 
| H00036 | Osteosarcoma | P08684
                            (marker) | 
| H00017 | Esophageal cancer | P35354
                            (related) | 
| H00025 | Penile cancer | P35354
                            (related) | 
| H00046 | Cholangiocarcinoma | P35354
                            (related) | 
| H00032 | Thyroid cancer | P37231
                            (related) | 
| H00409 | Type II diabetes mellitus | P37231
                            (related) | 
| H00420 | Familial partial lipodystrophy (FPL) | P37231
                            (related) | 
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) | Q03164
                            (related) Q03164 (marker) | 
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) | Q03164
                            (related) |