Phellinus igniarius
Species
KNApSAcK Entry
| Organism name | Phellinus igniarius |
|---|---|
| Genus | Phellinus |
| Family | Hymenochaetaceae |
| Kingdom | Fungi |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Phellinus igniarius |
|---|---|
| Linked NCBI taxonomy ID | 40472 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Hymenochaetaceae |
|---|---|
| ID | 40424 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Fungi |
|---|---|
| ID | 4751 |
Plant class
| Plant class | |
|---|---|
| ID |
Metabolite list (19)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00003652
|
Ergosterol
/ Ergosta-5,7,22-trien-3beta-ol |
CHEMBL222608
CHEMBL1232562 CHEMBL1512075 CHEMBL1741735 CHEMBL1965225 |
D004875
|
12 / 14 / 11 | No. 111 | No. 11 |
|
|
|
C00039174
|
Ethyl glucoside
|
CHEMBL2059297
|
No. 258 | No. 73 |
|
|||
|
C00001152
|
Trehalose
|
D014199
|
No. 423 | No. 73 |
|
|||
|
C00043789
|
Octadecyl ferulate
|
CHEMBL1669148
|
No. 447 |
|
||||
|
C00002500
|
Scopolin
|
CHEMBL225024
|
C417572
|
7 / 3 / 4 | No. 491 | No. 25 |
|
|
|
C00002668
|
Protocatechuic acid
/ 3,4-Dihydroxybenzoic acid |
CHEMBL37537
|
C009091
|
33 / 19 / 19 | 2 / 0 | No. 817 | No. 81 |
|
|
C00000615
|
Caffeic acid
|
CHEMBL145
CHEMBL1320034 |
68 / 64 / 63 | No. 904 | No. 6 |
|
||
|
C00002674
|
Syringic acid
/ 4-Hydroxy-3,5-dimethoxybenzoic acid |
CHEMBL1414
|
C001945
|
12 / 3 / 5 | No. 1073 |
|
||
|
C00018685
|
Nebularine
/ Purinosine / Ribosylpurine / Purine riboside / Purine-9-beta-D-ribofuranoside / 9-beta-D-Ribofuranosyl-9H-purine |
CHEMBL1399702
CHEMBL1476759 |
C005248
|
15 / 30 / 55 | No. 1761 |
|
||
|
C00002657
|
p-Formylphenol
/ 4-Hydroxybenzaldehyde / p-Hydroxybenzaldehyde |
CHEMBL14193
|
C011483
|
3 / 2 / 2 | No. 2076 |
|
||
|
C00018099
|
Catechaldehyde
/ Protocatechualdehyde / 3,4-Dihydroxybenzaldehyde |
CHEMBL222021
|
C005581
|
7 / 0 / 0 | 5 / 2 | No. 2076 |
|
|
|
C00019674
|
Uridine
|
CHEMBL68846
CHEMBL100259 CHEMBL265701 CHEMBL608294 CHEMBL609651 CHEMBL1092065 CHEMBL2093066 |
D014529
|
5 / 0 / 3 | 7 / 15 | No. 2366 |
|
|
|
C00041752
|
Phelligridin F
/ (-)-Phelligridin F |
CHEMBL488197
|
No. 3771 |
|
||||
|
C00043614
|
Isoergosterone
|
No. 3988 |
|
|||||
|
C00043576
|
Hispolon
|
CHEMBL452722
|
No. 4323 |
|
||||
|
C00039988
|
Phelligridin I
|
CHEMBL221760
|
1 / 0 / 0 | No. 4812 |
|
|||
|
C00039987
|
Phelligridin H
|
CHEMBL376755
|
1 / 0 / 0 | No. 4812 |
|
|||
|
C00043812
|
Phelligridin E
|
CHEMBL236399
|
No. 5287 |
|
||||
|
C00039989
|
Phelligridin J
|
CHEMBL373529
|
1 / 0 / 0 | No. 8573 |
|
Human Protein / Gene in interactions
100 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00000615 C00039987 C00039988 C00039989 | 0 / 0 |
| Q16790 | Carbonic anhydrase 9 | Lyase | C00000615 C00002500 C00002668 C00002674 | 0 / 1 |
| P00915 | Carbonic anhydrase 1 | Lyase | C00000615 C00002500 C00002668 C00002674 | 0 / 0 |
| O43570 | Carbonic anhydrase 12 | Lyase | C00000615 C00002500 C00002668 C00002674 | 1 / 2 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00000615 C00002500 C00002668 C00002674 | 1 / 2 |
| P43166 | Carbonic anhydrase 7 | Lyase | C00000615 C00002500 C00002668 C00002674 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000615 C00003652 C00018685 | 1 / 1 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00000615 C00002668 C00018099 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00000615 C00018099 C00018685 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00000615 C00002668 C00018099 | 0 / 0 |
| P22748 | Carbonic anhydrase 4 | Lyase | C00000615 C00002668 C00002674 | 1 / 1 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00000615 C00002668 C00003652 | 4 / 3 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00002668 C00018099 C00019674 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000615 C00003652 C00018685 | 0 / 1 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000615 C00003652 C00018685 | 1 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00000615 C00003652 C00018685 | 0 / 0 |
| P15121 | Aldose reductase | Enzyme | C00000615 C00002668 C00002674 | 0 / 0 |
| Q9ULX7 | Carbonic anhydrase 14 | Lyase | C00000615 C00002668 C00002674 | 0 / 0 |
| P23280 | Carbonic anhydrase 6 | Lyase | C00000615 C00002668 C00002674 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000615 C00003652 C00018685 | 0 / 1 |
| P03956 | Interstitial collagenase | M10A | C00000615 C00002668 | 0 / 1 |
| P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00000615 C00002668 | 0 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00000615 C00019674 | 0 / 3 |
| Q13093 | Platelet-activating factor acetylhydrolase | Enzyme | C00000615 C00002668 | 3 / 0 |
| P07451 | Carbonic anhydrase 3 | Lyase | C00000615 C00002674 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00000615 C00002668 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00000615 C00018099 | 0 / 0 |
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00000615 C00002668 | 1 / 1 |
| Q9Y2D0 | Carbonic anhydrase 5B, mitochondrial | Lyase | C00000615 C00002674 | 0 / 0 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00000615 C00018685 | 0 / 0 |
| Q9GZT9 | Egl nine homolog 1 | Enzyme | C00000615 C00002668 | 1 / 1 |
| P03372 | Estrogen receptor | NR3A1 | C00000615 C00002668 | 1 / 1 |
| P08253 | 72 kDa type IV collagenase | M10A | C00000615 C00002668 | 1 / 3 |
| P35218 | Carbonic anhydrase 5A, mitochondrial | Lyase | C00000615 C00002674 | 0 / 0 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00000615 C00018099 | 0 / 0 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00000615 C00002668 | 2 / 2 |
| P02545 | Prelamin-A/C | Unclassified protein | C00000615 C00018685 | 11 / 10 |
| O75496 | Geminin | Unclassified protein | C00002668 C00019674 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00000615 C00003652 | 0 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00000615 | 0 / 0 |
| P68871 | Hemoglobin subunit beta | Secreted protein | C00018685 | 4 / 4 |
| P17516 | Aldo-keto reductase family 1 member C4 | Enzyme | C00000615 | 1 / 0 |
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00000615 | 0 / 0 |
| P42330 | Aldo-keto reductase family 1 member C3 | Enzyme | C00000615 | 0 / 0 |
| Q8TDS4 | Hydroxycarboxylic acid receptor 2 | Hydroxycarboxylic acid receptor | C00000615 | 0 / 0 |
| P14902 | Indoleamine 2,3-dioxygenase 1 | Enzyme | C00002657 | 0 / 0 |
| P27708 | CAD protein | Enzyme | C00019674 | 0 / 0 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00018099 | 0 / 0 |
| Q9HA47 | Uridine-cytidine kinase 1 | Enzyme | C00019674 | 0 / 0 |
| P35348 | Alpha-1A adrenergic receptor | Adrenergic receptor | C00018685 | 0 / 0 |
| P22894 | Neutrophil collagenase | M10A | C00002668 | 0 / 0 |
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00018685 | 7 / 37 |
| P07711 | Cathepsin L1 | C1A | C00002668 | 0 / 0 |
| Q06124 | Tyrosine-protein phosphatase non-receptor type 11 | Tyr | C00000615 | 4 / 2 |
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00002668 | 0 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00003652 | 0 / 0 |
| P14679 | Tyrosinase | Oxidoreductase | C00000615 | 4 / 2 |
| P80404 | 4-aminobutyrate aminotransferase, mitochondrial | Transferase | C00002657 | 1 / 1 |
| P06280 | Alpha-galactosidase A | Enzyme | C00000615 | 1 / 1 |
| P35236 | Tyrosine-protein phosphatase non-receptor type 7 | Tyr | C00000615 | 0 / 0 |
| P16581 | E-selectin | Adhesion | C00002668 | 0 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00000615 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00003652 | 2 / 3 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00000615 | 1 / 8 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00000615 | 3 / 3 |
| Q04828 | Aldo-keto reductase family 1 member C1 | Enzyme | C00000615 | 0 / 0 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00000615 | 2 / 2 |
| Q01453 | Peripheral myelin protein 22 | Unclassified protein | C00000615 | 5 / 2 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00018685 | 0 / 0 |
| P54132 | Bloom syndrome protein | Enzyme | C00018685 | 1 / 2 |
| P22303 | Acetylcholinesterase | Hydrolase | C00002500 | 1 / 0 |
| Q8N1Q1 | Carbonic anhydrase 13 | Lyase | C00002500 | 0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00003652 | 0 / 0 |
| P14151 | L-selectin | Adhesion | C00002668 | 0 / 0 |
| P16109 | P-selectin | Adhesion | C00002668 | 1 / 0 |
| O60218 | Aldo-keto reductase family 1 member B10 | Enzyme | C00000615 | 0 / 0 |
| P51452 | Dual specificity protein phosphatase 3 | Ser_Thr_Tyr | C00000615 | 0 / 0 |
| P02768 | Serum albumin | Secreted protein | C00002668 | 0 / 0 |
| P52895 | Aldo-keto reductase family 1 member C2 | Enzyme | C00000615 | 1 / 0 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00018685 | 4 / 1 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00000615 | 0 / 0 |
| P22309 | UDP-glucuronosyltransferase 1-1 | Enzyme | C00003652 | 5 / 1 |
| P51649 | Succinate-semialdehyde dehydrogenase, mitochondrial | Oxidoreductase | C00002657 | 1 / 1 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00000615 | 3 / 1 |
| P31939 | Bifunctional purine biosynthesis protein PURH | Enzyme | C00003652 | 1 / 1 |
| P08254 | Stromelysin-1 | M10A | C00002668 | 1 / 0 |
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00000615 | 1 / 1 |
| Q12794 | Hyaluronidase-1 | Enzyme | C00000615 | 1 / 2 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00000615 | 0 / 0 |
| P24298 | Alanine aminotransferase 1 | Enzyme | C00000615 | 0 / 0 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00000615 | 2 / 2 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00000615 | 3 / 2 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00000615 | 1 / 1 |
| O00255 | Menin | Unclassified protein | C00000615 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00000615 | 1 / 2 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00002668 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00002668 | 1 / 4 |
| P07900 | Heat shock protein HSP 90-alpha | Other cytosolic protein | C00000615 | 0 / 0 |
| P08238 | Heat shock protein HSP 90-beta | Other cytosolic protein | C00000615 | 0 / 0 |
| P00813 | Adenosine deaminase | Hydrolase | C00018685 | 1 / 1 |
14 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 177 | AGER, RAGE | advanced glycosylation end product-specific receptor |
C00018099
|
| 6285 | S100B, NEF, S100, S100-B, S100beta | S100 calcium binding protein B |
C00018099
|
| 4087 | SMAD2, JV18, JV18-1, MADH2, MADR2, hMAD-2, hSMAD2 | SMAD family member 2 |
C00018099
|
| 4088 | SMAD3, HSPC193, HsT17436, JV15-2, LDS1C, LDS3, MADH3 | SMAD family member 3 |
C00018099
|
| 7040 | TGFB1, CED, DPD1, LAP, TGFB, TGFbeta | transforming growth factor, beta 1 |
C00018099
|
| 1312 | COMT | catechol-O-methyltransferase (EC:2.1.1.6) |
C00002668
|
| 2023 | ENO1, ENO1L1, MPB1, NNE, PPH | enolase 1, (alpha) (EC:4.2.1.11) |
C00002668
|
| 356 | FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6 | Fas ligand (TNF superfamily, member 6) |
C00019674
|
| 2993 | GYPA, CD235a, GPA, GPErik, GPSAT, HGpMiV, HGpMiXI, HGpSta(C), MN, MNS, PAS-2 | glycophorin A (MNS blood group) |
C00019674
|
| 4609 | MYC, MRTL, MYCC, bHLHe39, c-Myc | v-myc avian myelocytomatosis viral oncogene homolog |
C00019674
|
| 9154 | SLC28A1, CNT1, HCNT1 | solute carrier family 28 (concentrative nucleoside transporter), member 1 |
C00019674
|
| 9153 | SLC28A2, CNT2, HCNT2, HsT17153, SPNT1 | solute carrier family 28 (concentrative nucleoside transporter), member 2 |
C00019674
|
| 2030 | SLC29A1, ENT1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 |
C00019674
|
| 3177 | SLC29A2, DER12, ENT2, HNP36 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
C00019674
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (94)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #614279 | 46,xy sex reversal 8; srxy8 |
P17516
P52895 |
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #608688 | Aicar transformylase/imp cyclohydrolase deficiency |
P31939
|
| #103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
| #203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
| #606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
| #600807 | Asthma, susceptibility to |
Q13093
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #613985 | Beta-thalassemia |
P68871
|
| #603902 | Beta-thalassemia, dominant inclusion body type |
P68871
|
| #601816 | Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 |
P22309
|
| #210900 | Bloom syndrome; blm |
P54132
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #118300 | Charcot-marie-tooth disease and deafness |
Q01453
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #118220 | Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a |
Q01453
|
| #614466 | Coronary heart disease, susceptibility to, 6; chds6 |
P08254
|
| #218800 | Crigler-najjar syndrome, type i |
P22309
|
| #606785 | Crigler-najjar syndrome, type ii |
P22309
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #609820 | Erythrocytosis, familial, 3; ecyt3 |
Q9GZT9
|
| #133239 | Esophageal cancer |
P04637
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #301500 | Fabry disease |
P06280
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #613163 | Gaba-transaminase deficiency |
P80404
|
| #143500 | Gilbert syndrome |
P22309
|
| #232300 | Glycogen storage disease ii |
P10253
|
| #139393 | Guillain-barre syndrome, familial; gbs |
Q01453
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #140700 | Heinz body anemias |
P68871
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #237900 | Hyperbilirubinemia, transient familial neonatal; hblrtfn |
P22309
|
| #143860 | Hyperchlorhidrosis, isolated |
O43570
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #145900 | Hypertrophic neuropathy of dejerine-sottas |
Q01453
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #147050 | Ige responsiveness, atopic; iger |
Q13093
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #607785 | Juvenile myelomonocytic leukemia; jmml |
Q06124
|
| #151100 | Leopard syndrome 1 |
Q06124
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P00533
P04637 |
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #156250 | Metachondromatosis; metcds |
Q06124
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #601492 | Mucopolysaccharidosis, type ix; mps9 |
Q12794
|
| #259600 | Multicentric osteolysis, nodulosis, and arthropathy; mona |
P08253
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #162500 | Neuropathy, hereditary, with liability to pressure palsies; hnpp |
Q01453
|
| #163950 | Noonan syndrome 1; ns1 |
Q06124
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #614278 | Platelet-activating factor acetylhydrolase deficiency; pafad |
Q13093
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #600852 | Retinitis pigmentosa 17; rp17 |
P22748
|
| #102700 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-negative, nk cell-negative, due to adenosine deaminase deficiency |
P00813
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #603903 | Sickle cell anemia |
P68871
|
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| #601367 | Stroke, ischemic |
P16109
|
| #271980 | Succinic semialdehyde dehydrogenase deficiency; ssadhd |
P51649
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #278300 | Xanthinuria, type i |
P47989
|
| #112100 | Yt blood group antigen |
P22303
|
KEGG DISEASE (101)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H01302 | Hyperchlorhidrosis isolated (HCHLH) |
O43570
(related)
|
| H00021 | Renal cell carcinoma |
O43570
(marker)
P04637 (marker) Q16790 (marker) |
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P04637 (related) P04637 (marker) P35354 (related) |
| H00018 | Gastric cancer |
P00533
(related)
P04637 (related) |
| H00022 | Bladder cancer |
P00533
(related)
P04637 (related) P68871 (marker) |
| H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P04637 (related) P08253 (related) |
| H00030 | Cervical cancer |
P00533
(related)
|
| H00042 | Glioma |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00092 | T-B-Severe combined immunodeficiencies (SCIDs) |
P00813
(related)
|
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
Q01453 (related) |
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04637 (related) |
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
Q01196 (related) |
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) P68871 (marker) |
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) P08253 (related) P14780 (related) P35354 (related) |
| H00027 | Ovarian cancer |
P04637
(related)
|
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00031 | Breast cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
|
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
P14679 (marker) |
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00046 | Cholangiocarcinoma |
P04637
(related)
P35354 (related) |
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00125 | Fabry disease |
P06280
(related)
|
| H00472 | Torg-Winchester syndrome |
P08253
(related)
|
| H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00208 | Hyperbilirubinemia |
P22309
(related)
|
| H00527 | Retinitis pigmentosa (RP) |
P22748
(related)
|
| H00966 | AICA-ribosiduria |
P31939
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00192 | Xanthinuria |
P47989
(related)
|
| H00835 | Succinic semialdehyde dehydrogenase (SSADH) deficiency |
P51649
(related)
|
| H00094 | DNA repair defects |
P54132
(related)
|
| H00296 | Defects in RecQ helicases |
P54132
(related)
|
| H00228 | Thalassemia |
P68871
(related)
|
| H00229 | Sickle cell anemia (SCA) |
P68871
(related)
|
| H01257 | GABA-transaminase deficiency |
P80404
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H01296 | Hereditary neuropathy with liability to pressure palsies (HNPP) |
Q01453
(related)
|
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00523 | Noonan syndrome and related disorders |
Q06124
(related)
|
| H01018 | Metachondromatosis |
Q06124
(related)
|
| H00133 | Mucopolysaccharidosis type IX (MPS9) |
Q12794
(related)
|
| H00421 | Mucopolysaccharidosis (MPS) |
Q12794
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00236 | Congenital polycythemia |
Q9GZT9
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|
Diseases related to CTD interactions
17 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D002386 | Cataract |
C00018099
|
| D048909 | Diabetes Complications |
C00018099
|
| D000015 | Abnormalities, Multiple |
C00019674
|
| D000749 | Anemia, Megaloblastic |
C00019674
|
| D001919 | Bradycardia |
C00019674
|
| D002375 | Catalepsy |
C00019674
|
| D004342 | Drug Hypersensitivity |
C00019674
|
| D056486 | Drug-Induced Liver Injury |
C00019674
|
| D064420 | Drug-Related Side Effects and Adverse Reactions |
C00019674
|
| D005234 | Fatty Liver |
C00019674
|
| D007022 | Hypotension |
C00019674
|
| D028361 | Mitochondrial Diseases |
C00019674
|
| C538525 | Mitochondrial encephalopathy |
C00019674
|
| D017240 | Mitochondrial Myopathies |
C00019674
|
| D010523 | Peripheral Nervous System Diseases |
C00019674
|
| D011565 | Psoriasis |
C00019674
|
| D019956 | Stereotypic Movement Disorder |
C00019674
|