Zyzzya fuliginosa
Species
KNApSAcK Entry
| Organism name | Zyzzya fuliginosa |
|---|---|
| Genus | |
| Family | |
| Kingdom |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Zyzzya fuliginosa |
|---|---|
| Linked NCBI taxonomy ID | 1346156 |
| Linked level | species |
Family
| Family in NCBI taxonomy | |
|---|---|
| ID |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Metazoa |
|---|---|
| ID | 33208 |
Plant class
| Plant class | |
|---|---|
| ID |
Metabolite list (30)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00000856
|
4-Hydroxybenzoic acid
/ p-Hydroxybenzoic acid |
CHEMBL441343
|
C038193
|
21 / 7 / 16 | 2 / 1 | No. 817 | No. 81 |
|
|
C00028553
|
Makaluvamine K
|
CHEMBL272373
|
No. 1002 |
|
||||
|
C00046113
|
Makaluvamine P
|
No. 1002 |
|
|||||
|
C00039713
|
Makaluvamine E
|
CHEMBL509186
|
1 / 0 / 0 | No. 1002 |
|
|||
|
C00028555
|
Makaluvamine M
|
CHEMBL452774
|
1 / 0 / 0 | No. 1002 |
|
|||
|
C00028548
|
Makaluvamine D
|
CHEMBL453817
|
1 / 0 / 0 | No. 1002 |
|
|||
|
C00028552
|
Makaluvamine J
|
CHEMBL560042
|
No. 1002 |
|
||||
|
C00026943
|
Veiutamine
|
No. 1002 |
|
|||||
|
C00028549
|
Makaluvamine G
|
CHEMBL454071
|
No. 1002 |
|
||||
|
C00028554
|
Makaluvamine L
|
CHEMBL1190852
|
No. 1002 |
|
||||
|
C00001396
|
L-Tryptophan
|
CHEMBL54976
CHEMBL292303 CHEMBL484901 |
49 / 41 / 39 | No. 1432 | No. 4 |
|
||
|
C00046044
|
Isobatzelline C
|
CHEMBL447517
|
No. 1773 |
|
||||
|
C00028556
|
Makaluvamine N
|
No. 1773 |
|
|||||
|
C00028551
|
Makaluvamine I
|
CHEMBL1183639
|
No. 1773 |
|
||||
|
C00033155
|
Makaluvamine A
|
CHEMBL449905
|
1 / 0 / 0 | No. 1773 |
|
|||
|
C00026843
|
Batzelline D
|
No. 2288 |
|
|||||
|
C00045680
|
Batzelline C
|
No. 2288 |
|
|||||
|
C00043128
|
Zyzzyanone D
|
CHEMBL463287
|
No. 3018 |
|
||||
|
C00026645
|
Zyzzyanone A
|
No. 3018 |
|
|||||
|
C00043127
|
Zyzzyanone C
|
CHEMBL463286
|
No. 3018 |
|
||||
|
C00043126
|
Zyzzyanone B
|
CHEMBL1162275
|
No. 3018 |
|
||||
|
C00001386
|
L-Phenylalanine
|
CHEMBL25080
CHEMBL301523 CHEMBL379630 |
27 / 18 / 14 | No. 3303 |
|
|||
|
C00027084
|
Damirone B
|
CHEMBL462951
|
No. 4331 |
|
||||
|
C00042448
|
Damirone A
|
CHEMBL559637
|
No. 4331 |
|
||||
|
C00028550
|
Makaluvamine H
|
CHEMBL465308
|
No. 4331 |
|
||||
|
C00033156
|
Makaluvamine B
|
CHEMBL2153157
|
No. 4477 |
|
||||
|
C00026842
|
Isobatzelline E
|
No. 4477 |
|
|||||
|
C00032640
|
3,7-Dimethylguanine
|
No. 5738 |
|
|||||
|
C00027086
|
Makaluvamine C
|
No. 6519 |
|
|||||
|
C00026938
|
Discorhabdin Q
/ (-)-Discorhabdin Q / (-)-16,17-Dehydrodiscorhabdin B |
CHEMBL490511
|
No. 6581 |
|
Human Protein / Gene in interactions
63 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P11388 | DNA topoisomerase 2-alpha | Isomerase | C00028548 C00028555 C00033155 C00039713 | 0 / 0 |
| P35218 | Carbonic anhydrase 5A, mitochondrial | Lyase | C00000856 C00001386 C00001396 | 0 / 0 |
| P23280 | Carbonic anhydrase 6 | Lyase | C00000856 C00001386 C00001396 | 0 / 0 |
| O43570 | Carbonic anhydrase 12 | Lyase | C00000856 C00001386 C00001396 | 1 / 2 |
| Q9Y2D0 | Carbonic anhydrase 5B, mitochondrial | Lyase | C00000856 C00001386 C00001396 | 0 / 0 |
| Q9ULX7 | Carbonic anhydrase 14 | Lyase | C00000856 C00001386 C00001396 | 0 / 0 |
| P43166 | Carbonic anhydrase 7 | Lyase | C00000856 C00001386 C00001396 | 0 / 0 |
| P22748 | Carbonic anhydrase 4 | Lyase | C00000856 C00001386 C00001396 | 1 / 1 |
| P07451 | Carbonic anhydrase 3 | Lyase | C00000856 C00001386 C00001396 | 0 / 0 |
| Q16790 | Carbonic anhydrase 9 | Lyase | C00000856 C00001386 C00001396 | 0 / 1 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00000856 C00001386 C00001396 | 1 / 2 |
| P00915 | Carbonic anhydrase 1 | Lyase | C00000856 C00001386 C00001396 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001386 C00001396 | 0 / 1 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00001386 C00001396 | 0 / 0 |
| Q9Y263 | Phospholipase A-2-activating protein | Unclassified protein | C00001386 C00001396 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001386 C00001396 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00001386 C00001396 | 0 / 1 |
| P05186 | Alkaline phosphatase, tissue-nonspecific isozyme | Enzyme | C00001386 C00001396 | 3 / 1 |
| Q9HAW7 | UDP-glucuronosyltransferase 1-7 | Enzyme | C00000856 C00001396 | 0 / 0 |
| P09923 | Intestinal-type alkaline phosphatase | Enzyme | C00001386 C00001396 | 0 / 0 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00001386 C00001396 | 2 / 0 |
| Q9HAW8 | UDP-glucuronosyltransferase 1-10 | Enzyme | C00000856 C00001396 | 0 / 0 |
| Q05BR4 | SLC16A10 protein | Unclassified protein | C00001386 C00001396 | 0 / 0 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001386 C00001396 | 1 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001386 C00001396 | 1 / 1 |
| P39748 | Flap endonuclease 1 | Enzyme | C00001396 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00001396 | 0 / 0 |
| P42858 | Huntingtin | Unclassified protein | C00001396 | 1 / 1 |
| O75496 | Geminin | Unclassified protein | C00001396 | 0 / 0 |
| O60656 | UDP-glucuronosyltransferase 1-9 | Enzyme | C00000856 | 0 / 0 |
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00001396 | 0 / 0 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00000856 | 1 / 8 |
| P54132 | Bloom syndrome protein | Enzyme | C00001396 | 1 / 2 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00001396 | 1 / 2 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00001386 | 0 / 1 |
| P14679 | Tyrosinase | Oxidoreductase | C00001386 | 4 / 2 |
| P80404 | 4-aminobutyrate aminotransferase, mitochondrial | Transferase | C00000856 | 1 / 1 |
| Q9UQ49 | Sialidase-3 | Enzyme | C00000856 | 0 / 0 |
| P02768 | Serum albumin | Secreted protein | C00001396 | 0 / 0 |
| Q92887 | Canalicular multispecific organic anion transporter 1 | Unclassified protein | C00001396 | 1 / 1 |
| Q01453 | Peripheral myelin protein 22 | Unclassified protein | C00001396 | 5 / 2 |
| Q9HAW9 | UDP-glucuronosyltransferase 1-8 | Enzyme | C00000856 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00001386 | 1 / 1 |
| P48775 | Tryptophan 2,3-dioxygenase | Enzyme | C00001396 | 0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00001396 | 0 / 0 |
| P51580 | Thiopurine S-methyltransferase | Enzyme | C00000856 | 1 / 1 |
| P51649 | Succinate-semialdehyde dehydrogenase, mitochondrial | Oxidoreductase | C00000856 | 1 / 1 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00001386 | 3 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00001396 | 0 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00001396 | 3 / 2 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00001396 | 4 / 3 |
| Q99549 | M-phase phosphoprotein 8 | Unclassified protein | C00001396 | 0 / 0 |
| P19224 | UDP-glucuronosyltransferase 1-6 | Enzyme | C00000856 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00001386 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00001396 | 11 / 10 |
| P08254 | Stromelysin-1 | M10A | C00001396 | 1 / 0 |
| Q16773 | Kynurenine--oxoglutarate transaminase 1 | Enzyme | C00001396 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001396 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00001396 | 0 / 0 |
| O00255 | Menin | Unclassified protein | C00001396 | 2 / 5 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00001396 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00001396 | 1 / 4 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00001396 | 0 / 0 |
2 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 3952 | LEP, LEPD, OB, OBS | leptin |
C00000856
|
| 6817 | SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) |
C00000856
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (53)
| OMIM | preferred title | UniProt |
|---|---|---|
| #103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
| #203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
| #606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
| #210900 | Bloom syndrome; blm |
P54132
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #118300 | Charcot-marie-tooth disease and deafness |
Q01453
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #118220 | Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a |
Q01453
|
| #614466 | Coronary heart disease, susceptibility to, 6; chds6 |
P08254
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #237500 | Dubin-johnson syndrome; djs |
Q92887
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #613163 | Gaba-transaminase deficiency |
P80404
|
| #139393 | Guillain-barre syndrome, familial; gbs |
Q01453
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #143100 | Huntington disease; hd |
P42858
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #143860 | Hyperchlorhidrosis, isolated |
O43570
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #145900 | Hypertrophic neuropathy of dejerine-sottas |
Q01453
|
| #146300 | Hypophosphatasia, adult |
P05186
|
| #241510 | Hypophosphatasia, childhood |
P05186
|
| #241500 | Hypophosphatasia, infantile |
P05186
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #211980 | Lung cancer |
P00533
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #162500 | Neuropathy, hereditary, with liability to pressure palsies; hnpp |
Q01453
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #600852 | Retinitis pigmentosa 17; rp17 |
P22748
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
| #271980 | Succinic semialdehyde dehydrogenase deficiency; ssadhd |
P51649
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #610460 | Thiopurine s-methyltransferase deficiency |
P51580
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
KEGG DISEASE (55)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H01302 | Hyperchlorhidrosis isolated (HCHLH) |
O43570
(related)
|
| H00021 | Renal cell carcinoma |
O43570
(marker)
Q16790 (marker) |
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
|
| H00018 | Gastric cancer |
P00533
(related)
|
| H00022 | Bladder cancer |
P00533
(related)
|
| H00028 | Choriocarcinoma |
P00533
(related)
|
| H00030 | Cervical cancer |
P00533
(related)
|
| H00042 | Glioma |
P00533
(related)
P00533 (marker) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) |
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
Q01453 (related) |
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
|
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
| H00213 | Hypophosphatasia |
P05186
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
| H00038 | Malignant melanoma |
P14679
(marker)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00527 | Retinitis pigmentosa (RP) |
P22748
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00059 | Huntington's disease (HD) |
P42858
(related)
|
| H00964 | Thiopurine S-methyltransferase deficiency (TPMT deficiency) |
P51580
(related)
|
| H00835 | Succinic semialdehyde dehydrogenase (SSADH) deficiency |
P51649
(related)
|
| H00094 | DNA repair defects |
P54132
(related)
|
| H00296 | Defects in RecQ helicases |
P54132
(related)
|
| H01257 | GABA-transaminase deficiency |
P80404
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H01296 | Hereditary neuropathy with liability to pressure palsies (HNPP) |
Q01453
(related)
|
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00208 | Hyperbilirubinemia |
Q92887
(related)
|