Annona cherimola

• Index
• Plant Species
• Natural Activity
• Metabolite list (45)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Annona cherimola
Genus	Annona
Family	Annonaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Annona cherimola
Linked NCBI taxonomy ID	49314
Linked level	species

Family

Family in NCBI taxonomy	Annonaceae
ID	22140

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	Magnoliophyta
ID	3398

Natural Activity

List (13)

Species	Activity
Annona cherimola Mill.	Antiprotozoal
Annona cherimola Mill.	Antiseptic
Annona cherimola Mill.	Cathartic
Annona cherimola Mill.	Cytotoxic
Annona cherimola Mill.	Emetic
Annona cherimola Mill.	Filaricide
Annona cherimola Mill.	Insecticide
Annona cherimola Mill.	Parasiticide
Annona cherimola Mill.	Pediculicide
Annona cherimola Mill.	Piscicide
Annona cherimola Mill.	Poison
Annona cherimola Mill.	Stomachic
Annona cherimola Mill.	Uterocontractant

Metabolite list (45)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00001323	Squamocin	CHEMBL41177 CHEMBL502366 CHEMBL453405 CHEMBL452936	C059660			No. 6	No. 70
C00038511	Aromin A / (+)-Aromin A					No. 6	No. 70
C00001872	Isocorydine / (+)-Isocorydine / L-(+)-Isocorydine / (S)-(+)-Isocorydine	CHEMBL489525 CHEMBL1376826		14 / 7 / 10		No. 20	No. 4
C00001806	Anolobine / (-)-Anolobine	CHEMBL257746				No. 20	No. 4
C00027281	Anonaine	CHEMBL401798	C098138	1 / 0 / 0		No. 20	No. 4
C00025991	O-Nornuciferine / (-)-Nornuciferine / (-)-N-Methylasimilobine	CHEMBL2316499				No. 20	No. 4
C00001928	Xylopine / (-)-Xylopine	CHEMBL227689 CHEMBL452201	C062700			No. 20	No. 4
C00025675	Lauroscholtzine / 2-O-Methylboldine / N-Methyllaurotetanine / (+)-N-Methyllaurotetanine	CHEMBL464099		1 / 1 / 0		No. 20	No. 4
C00025231	Asimilobine / (-)-Asimilobine	CHEMBL389271 CHEMBL469423	C054614	1 / 1 / 0		No. 20	No. 4
C00027409	Laurotetanin / Laurotetanine / (+)-Laurotetanine	CHEMBL464098	C008256			No. 20	No. 4
C00027438	Sanjoinine Ib / Norisocorydine	CHEMBL465212				No. 20	No. 4
C00025241	Kikemanin / Kikemanine / Corydalmine / Schefferine / (-)-Kikemanine / (-)-Corydalmine	CHEMBL448891 CHEMBL1209608 CHEMBL2334894	C058198	5 / 3 / 0		No. 37	No. 4
C00002631	(+)-Lirioresinol B / (+)-Syringaresinol	CHEMBL361362 CHEMBL402653	C042192	1 / 0 / 0		No. 38	No. 21
C00027457	Oxoglaucine / O-Methylatheroline	CHEMBL470881	C111587	25 / 27 / 24		No. 74
C00025319	Oxoxylopin / Oxoxylopine / Lanuginosine	CHEMBL389400		1 / 4 / 2		No. 74
C00025935	Lysicamine / Oxonuciferine	CHEMBL510090	C069090			No. 74
C00027456	Oxoanolobine					No. 74
C00001878	Liriodenine / Oxoushinsunine / Spermatheridine	CHEMBL37736	C026980	5 / 3 / 1		No. 74
C00025995	Oxonantenine	CHEMBL1270949				No. 74
C00027870	Anomoline					No. 253	No. 4
C00029944	Cherimolacyclopeptide G					No. 290
C00029941	Cherimolacyclopeptide C / Cyclo(L-alanyl-L-alanyl-L-tryptophyl-L-isoleucyl-L-prolyl-L-prolylglycyl)	CHEMBL510705				No. 290
C00001910	Reticuline / (+)-Reticuline	CHEMBL235212 CHEMBL401501 CHEMBL464734	C003298	1 / 0 / 0		No. 345	No. 4
C00026908	Cheritamine					No. 442
C00025324	N-cis-Feruloyltyramine / cis-N-Feruloyltyramine	CHEMBL206555 CHEMBL451720		1 / 4 / 2		No. 499
C00034085	N-p-Coumaroyltyramine	CHEMBL64286				No. 499
C00027423	N-Formylanonaine / (-)-N-Formylanonaine	CHEMBL1170090		1 / 4 / 2		No. 553
C00027444	Michelalbine / Norushinsunine	CHEMBL464657 CHEMBL1618042				No. 553
C00025258	Micheline A / (-)-Ushinsunine	CHEMBL221034 CHEMBL1617041 CHEMBL2009013		1 / 0 / 0		No. 553
C00001905	Milthanthine / Pronuciferine / (+)-Pronuciferine / N-Methylstepharine / N,O-Dimethylcrotonosine	CHEMBL237766				No. 688
C00025272	Stepharine / (+)-Stepharine	CHEMBL463957 CHEMBL1975436	C009320			No. 688
C00027480	Romucosine H					No. 889
C00027477	Romucosine / (-)-Romucosine					No. 889
C00036730	Annocherine B / (+)-Annocherine B					No. 1137
C00036729	Annocherine A / (+)-Annocherine A					No. 1137
C00029939	Cherimolacyclopeptide A					No. 1183
C00029940	Cherimolacyclopeptide B					No. 1183
C00029943	Cherimolacyclopeptide F					No. 1183
C00027167	Thalifoline	CHEMBL1813177				No. 2199
C00027321	Cherianoine					No. 3076	No. 7
C00036764	Artabonatine B / (-)-Artabonatine B	CHEMBL458523		1 / 4 / 2		No. 3212
C00027346	Doryphornine					No. 3424
C00026406	Cherimoline					No. 5258
C00029942	Cherimolacyclopeptide D					No. 5577
C00027322	Cherinonaine					No. 5792

Human Protein / Gene in interactions

49 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00001872 C00027457	1 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00001872 C00027457	0 / 0
P08908	5-hydroxytryptamine receptor 1A	Serotonin receptor	C00025241 C00025675	1 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00001872 C00027457	0 / 1
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00001872 C00027457	1 / 1
P14679	Tyrosinase	Oxidoreductase	C00025324 C00027423	4 / 2
P00734	Prothrombin	S1A	C00025319 C00036764	4 / 2
O75496	Geminin	Unclassified protein	C00001872 C00027457	0 / 0
Q14761	Protein tyrosine phosphatase receptor type C-associated protein	Enzyme	C00001878 C00027281	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00001872 C00027457	0 / 1
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00027457	1 / 2
P32297	Neuronal acetylcholine receptor subunit alpha-3	CHRN alpha	C00001878	1 / 0
P17787	Neuronal acetylcholine receptor subunit beta-2	CHRN beta	C00001878	1 / 1
P43681	Neuronal acetylcholine receptor subunit alpha-4	CHRN alpha	C00001878	1 / 1
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00027457	1 / 0
P11387	DNA topoisomerase 1	Isomerase	C00002631	0 / 0
P14416	D(2) dopamine receptor	Dopamine receptor	C00025241	2 / 0
P24941	Cyclin-dependent kinase 2	Cdc2	C00001872	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00001872	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00027457	0 / 0
P42858	Huntingtin	Unclassified protein	C00027457	1 / 1
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00027457	2 / 0
P02545	Prelamin-A/C	Unclassified protein	C00027457	11 / 10
Q9Y253	DNA polymerase eta	Enzyme	C00027457	1 / 1
P30926	Neuronal acetylcholine receptor subunit beta-4	CHRN beta	C00001878	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00027457	0 / 0
Q92793	CREB-binding protein	Enzyme	C00027457	1 / 1
O14757	Serine/threonine-protein kinase Chk1	Chk1	C00025258	0 / 0
P13726	Tissue factor	Membrane receptor	C00025241	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00027457	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00001872	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00001872	3 / 3
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00027457	2 / 2
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00027457	0 / 0
P22303	Acetylcholinesterase	Hydrolase	C00025231	1 / 0
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00025241	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00001910	0 / 0
P29466	Caspase-1	C14	C00027457	0 / 0
P06746	DNA polymerase beta	Enzyme	C00027457	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00027457	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00027457	4 / 3
P21728	D(1A) dopamine receptor	Dopamine receptor	C00025241	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00027457	0 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00027457	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00027457	1 / 1
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00001872	1 / 0
Q13951	Core-binding factor subunit beta	Unclassified protein	C00001872	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00001872	1 / 4
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00001872	0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions