| Organism name | Artemisia spp. |
|---|---|
| Genus | Artemisia |
| Family | Asteraceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Artemisia |
|---|---|
| Linked NCBI taxonomy ID | 4219 |
| Linked level | genus |
| Family in NCBI taxonomy | Asteraceae |
|---|---|
| ID | 4210 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | asterids |
|---|---|
| ID | 71274 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00006381
|
Isoshaftoside
/ Isoschaftoside / Apigenin 6-C-alpha-L-arabinopyranoside-8-C-beta-D-glucopyranoside |
No. 1 | No. 15 |
|
||||
|
C00005373
|
Hirsutrin
/ Isoquercetin / Isoquercetrin / (-)-Isoquercetrin / Quercetin 3-glucoside / Quercetin 3-O-beta-D-glucoside / Quercetin-3-O-beta-D-glucopyranoside / Quercetin 3-O-beta-D-glucopyranoside / (-)-Quercetin-3-O-beta-D-glucopyranoside |
CHEMBL33027
CHEMBL309323 CHEMBL250450 CHEMBL251254 CHEMBL457304 CHEMBL1098724 CHEMBL2337335 CHEMBL2337336 |
38 / 43 / 34 | No. 2 | No. 15 |
|
||
|
C00004688
|
Eupatolitin
/ 3,3',4',5-tetrahydroxy-6,7-dimethoxyflavone / 2-(3,4-Dihydroxyphenyl)-3,5-dihydroxy-6,7-dimethoxy-4H-1-benzopyran-4-one |
No. 3 | No. 15 |
|
||||
|
C00004638
|
Quercetin 3,7-dimethyl ether
/ 5,3',4'-Trihydroxy-3,7-dimethoxyflavone / 2-(3,4-Dihydroxyphenyl)-5-hydroxy-3,7-dimethoxy-4H-1-benzopyran-4-one |
CHEMBL164861
|
C065497
|
2 / 1 / 2 | No. 3 | No. 15 |
|
|
|
C00004588
|
3,5-Dihydroxy-6,7,8-trimethoxyflavone
/ 3,5-Dihydroxy-6,7,8-trimethoxy-2-phenyl-4H-1-benzopyran-4-one |
CHEMBL1416487
|
8 / 13 / 7 | No. 3 | No. 15 |
|
||
|
C00004706
|
Bonanzin
/ Quercetagetin 3,6,3',4'-tetramethyl ether / 5,7-Dihydroxy-3,6,3',4'-tetramethoxyflavone / 2-(3,4-Dimethoxyphenyl)-5,7-dihydroxy-3,6-dimethoxy-4H-1-benzopyran-4-one |
No. 8 | No. 15 |
|
||||
|
C00008299
|
Eriodictyol 7,3'-dimethyl ether
|
No. 25 | No. 14 |
|
||||
|
C00000982
|
Naringenin
/ (-)-Naringenin |
CHEMBL9352
CHEMBL32571 |
C005273
|
57 / 46 / 40 | 35 / 10 | No. 25 | No. 14 |
|
|
C00008556
|
Aromadendrin 7-methyl ether
|
CHEMBL491541
CHEMBL452130 |
No. 42 | No. 14 |
|
|||
|
C00008581
|
Taxifolin 7,3'-dimethyl ether
|
No. 42 | No. 14 |
|
||||
|
C00003363
|
Balchanin
/ Santamarin / Santamarine |
CHEMBL89311
CHEMBL366059 |
C016722
|
3 / 0 / 0 | No. 69 | No. 38 |
|
|
|
C00012386
|
Chamissellin
/ Deacetyllaurenobiolide / Desacetyllaurenobiolide |
No. 107 | No. 38 |
|
||||
|
C00012362
|
Speciformin
/ Spiciformin |
No. 227 | No. 38 |
|
||||
|
C00012969
|
Artemine
/ 11S-Artemin / Artemin (sesquiterpene) / [3S-(3alpha,3aalpha,5abeta,6beta,9aalpha,9bbeta)]-Decahydro-6,9a-dihydroxy-3,5a-dimethyl-9-methylenenaphtho[1,2-b]furan-2(3H)-one |
CHEMBL1595875
|
2 / 1 / 4 | No. 275 |
|
|||
|
C00003205
|
Achillin
|
CHEMBL517040
CHEMBL1322934 CHEMBL1741501 |
C476810
|
12 / 7 / 10 | No. 298 | No. 38 |
|
|
|
C00003248
|
Leucodin
/ Desacetoxymatricarin |
CHEMBL517040
CHEMBL1322934 CHEMBL1741501 |
C476809
|
12 / 7 / 10 | No. 298 | No. 38 |
|
|
|
C00003110
|
Caryophyllene
/ (E)-Caryophyllene / beta-Caryophyllene / (-)-(E)-Caryophyllene / (E)-beta-Caryophyllene |
CHEMBL445740
CHEMBL448700 |
2 / 3 / 7 | No. 478 | No. 38 |
|
||
|
C00002500
|
Scopolin
|
CHEMBL225024
|
C417572
|
7 / 3 / 4 | No. 491 | No. 25 |
|
|
|
C00002458
|
Cichoriin
|
C410941
|
No. 491 | No. 25 |
|
|||
|
C00002751
|
Isochlorogenic acid b
/ 3,4-Dicaffeoylquinic acid |
CHEMBL358821
CHEMBL149674 CHEMBL177126 CHEMBL249448 CHEMBL453276 CHEMBL453537 CHEMBL1972460 |
2 / 0 / 0 | No. 518 | No. 6 |
|
||
|
C00013075
|
Pseudosantonin
/ [3S-(3alpha,3aalpha,4alpha,5abeta,9balpha)]-3a,5,5a,7,8,9b-Hexahydro-4-hydroxy-3,5a,9-trimethylnaphtho[1,2-b]furan-2,6(3H,4H)-dione |
CHEMBL1993611
|
No. 528 |
|
||||
|
C00013082
|
Finitin
/ [3S-(3alpha,3aalpha,5abeta,9balpha)]-3a,5,5a,7,8,9b-Hexahydro-3,5a,9-trimethylnaphtho[1,2-b]furan-2,6(3H,4H)-dione |
No. 528 |
|
|||||
|
C00011018
|
2,10-Bornanediol
|
No. 649 | No. 35 |
|
||||
|
C00013044
|
Arbusculin C
/ [3aS-(3aalpha,5abeta,9aalpha,9bbeta)]-Decahydro-9a-hydroxy-5a-methyl-3,9-bis(methylene)naphtho[1,2-b]furan-2(3H)-one |
No. 658 |
|
|||||
|
C00000810
|
(-)-Menthol
|
CHEMBL41763
CHEMBL256087 CHEMBL470670 CHEMBL1907990 CHEMBL1907991 CHEMBL2106989 |
15 / 9 / 11 | No. 901 | No. 35 |
|
||
|
C00010931
|
(R)-(+)-alpha-Terpineol
/ (R)-(+)-p-Menth-1-en-8-ol |
CHEMBL447597
CHEMBL449810 |
3 / 16 / 11 | No. 983 | No. 35 |
|
||
|
C00010932
|
(S)-(-)-alpha-Terpineol
/ (S)-(-)-p-Menth-1-en-8-ol |
CHEMBL447597
CHEMBL449810 |
3 / 16 / 11 | No. 983 | No. 35 |
|
||
|
C00011036
|
[1S-[1alpha,5alpha(7R*)]]-7-hydroxy-6,6-dimethyl-2-methylenebicyclo[3.1.1]heptan-3-one
|
No. 1561 | No. 35 |
|
||||
|
C00010891
|
(S)-(+)-Carvone
|
CHEMBL15676
CHEMBL501949 |
8 / 9 / 9 | No. 1740 | No. 35 |
|
||
|
C00003364
|
Semenen
/ Santonin / a-Santonin / (-)-Santonin / (-)-alpha-Santonin / [3S-(3alpha,3aalpha,5abeta,9bbeta)]-3a,5,5a,9b-Tetrahydro-3,5a,9-trimethylnaphtho[1,2-b]furan-2,8(3H,4H)-dione |
CHEMBL226231
CHEMBL259254 CHEMBL1357930 CHEMBL1570028 CHEMBL1600999 CHEMBL1717567 CHEMBL2103785 |
D012500
|
14 / 11 / 8 | No. 2117 | No. 38 |
|
|
|
C00010825
|
Isocineple
/ 1,4-Cineole |
C058951
|
No. 4112 | No. 35 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q9UNA4 | DNA polymerase iota | Enzyme | C00000982 C00003205 C00003248 C00005373 C00012969 | 0 / 0 |
| O00255 | Menin | Unclassified protein | C00000982 C00003110 C00003205 C00003248 C00010891 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00000982 C00003110 C00003205 C00003248 C00010891 | 1 / 2 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000982 C00003205 C00003248 C00003364 | 0 / 1 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000982 C00003205 C00003248 C00003364 | 1 / 0 |
| P22310 | UDP-glucuronosyltransferase 1-4 | Enzyme | C00000810 C00000982 C00010931 C00010932 | 3 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00003205 C00003248 C00004588 C00010891 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000982 C00003205 C00003248 C00003364 | 1 / 1 |
| P22309 | UDP-glucuronosyltransferase 1-1 | Enzyme | C00000810 C00000982 C00010931 C00010932 | 5 / 1 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00000982 C00003205 C00003248 C00003364 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000982 C00003205 C00003248 C00003364 | 0 / 1 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00000810 C00000982 C00005373 | 0 / 3 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00003205 C00003248 C00010891 | 0 / 0 |
| P15121 | Aldose reductase | Enzyme | C00000982 C00002751 C00005373 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00000982 C00003364 C00005373 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00005373 C00010931 C00010932 | 11 / 10 |
| P04062 | Glucosylceramidase | Enzyme | C00000982 C00005373 | 6 / 4 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00004588 C00005373 | 4 / 3 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00000982 C00005373 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00003364 C00005373 | 0 / 0 |
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00004588 C00005373 | 1 / 1 |
| P22303 | Acetylcholinesterase | Hydrolase | C00000982 C00002500 | 1 / 0 |
| Q9HAW9 | UDP-glucuronosyltransferase 1-8 | Enzyme | C00000810 C00000982 | 0 / 0 |
| Q9UNQ0 | ATP-binding cassette sub-family G member 2 | ATP binding cassette | C00000982 C00005373 | 2 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00004588 C00005373 | 0 / 0 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00000982 C00003364 | 0 / 1 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00003364 C00005373 | 0 / 0 |
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00000982 C00005373 | 1 / 1 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00003205 C00003248 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00003364 C00004588 | 7 / 3 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00000982 C00003364 | 1 / 1 |
| P41143 | Delta-type opioid receptor | Opioid receptor | C00000982 C00005373 | 0 / 0 |
| P54855 | UDP-glucuronosyltransferase 2B15 | Enzyme | C00000810 C00000982 | 0 / 0 |
| Q9NPH5 | NADPH oxidase 4 | Enzyme | C00004638 C00005373 | 0 / 0 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00000810 C00005373 | 0 / 1 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00003205 C00003248 | 2 / 0 |
| P36888 | Receptor-type tyrosine-protein kinase FLT3 | Pdgfr | C00000982 C00005373 | 1 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00000810 C00005373 | 1 / 4 |
| P41145 | Kappa-type opioid receptor | Opioid receptor | C00000982 C00005373 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00000982 | 1 / 1 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00000810 | 2 / 3 |
| O75828 | Carbonyl reductase [NADPH] 3 | Enzyme | C00000982 | 0 / 0 |
| P07237 | Protein disulfide-isomerase | Enzyme | C00005373 | 0 / 0 |
| O43570 | Carbonic anhydrase 12 | Lyase | C00002500 | 1 / 2 |
| P04278 | Sex hormone-binding globulin | Secreted protein | C00000982 | 0 / 0 |
| P24864 | G1/S-specific cyclin-E1 | Other cytosolic protein | C00000982 | 0 / 2 |
| P39748 | Flap endonuclease 1 | Enzyme | C00005373 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00003364 | 0 / 0 |
| P16152 | Carbonyl reductase [NADPH] 1 | Enzyme | C00000982 | 0 / 0 |
| P24941 | Cyclin-dependent kinase 2 | Cdc2 | C00000982 | 0 / 0 |
| P16662 | UDP-glucuronosyltransferase 2B7 | Enzyme | C00000810 | 0 / 0 |
| O60656 | UDP-glucuronosyltransferase 1-9 | Enzyme | C00000810 | 0 / 0 |
| P08183 | Multidrug resistance protein 1 | drug | C00000982 | 1 / 0 |
| P04798 | Cytochrome P450 1A1 | Cytochrome P450 1A1 | C00000982 | 0 / 0 |
| Q92731 | Estrogen receptor beta | NR3A2 | C00000982 | 0 / 1 |
| P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | C00005373 | 0 / 0 |
| P00915 | Carbonic anhydrase 1 | Lyase | C00002500 | 0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00004588 | 0 / 0 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00002500 | 1 / 2 |
| Q04206 | Transcription factor p65 | Transcription Factor | C00003363 | 0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00005373 | 1 / 1 |
| P09923 | Intestinal-type alkaline phosphatase | Enzyme | C00005373 | 0 / 0 |
| P05186 | Alkaline phosphatase, tissue-nonspecific isozyme | Enzyme | C00005373 | 3 / 1 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00010891 | 3 / 1 |
| Q9NPD5 | Solute carrier organic anion transporter family member 1B3 | Electrochemical transporter | C00000982 | 1 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00000982 | 0 / 0 |
| P62158 | Calmodulin | Unclassified protein | C00000982 | 1 / 0 |
| P11511 | Cytochrome P450 19A1 | Cytochrome P450 19A1 | C00000982 | 2 / 2 |
| P14679 | Tyrosinase | Oxidoreductase | C00005373 | 4 / 2 |
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00000982 | 5 / 3 |
| Q16678 | Cytochrome P450 1B1 | Cytochrome P450 1B1 | C00000982 | 4 / 4 |
| P06280 | Alpha-galactosidase A | Enzyme | C00005373 | 1 / 1 |
| P04745 | Alpha-amylase 1 | Enzyme | C00000982 | 0 / 0 |
| P18054 | Arachidonate 12-lipoxygenase, 12S-type | Enzyme | C00000982 | 2 / 0 |
| Q96RI1 | Bile acid receptor | NR1H4 | C00000810 | 0 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00005373 | 0 / 0 |
| P10696 | Alkaline phosphatase, placental-like | Enzyme | C00005373 | 0 / 1 |
| Q13315 | Serine-protein kinase ATM | Atypical serine/threonine protein kinase PIKK subfamily | C00012969 | 1 / 4 |
| Q16790 | Carbonic anhydrase 9 | Lyase | C00002500 | 0 / 1 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00000982 | 3 / 3 |
| Q8N1Q1 | Carbonic anhydrase 13 | Lyase | C00002500 | 0 / 0 |
| Q92887 | Canalicular multispecific organic anion transporter 1 | Unclassified protein | C00000982 | 1 / 1 |
| O75762 | Transient receptor potential cation channel subfamily A member 1 | Unclassified protein | C00000810 | 1 / 0 |
| P51449 | Nuclear receptor ROR-gamma | Nuclear hormone receptor subfamily 1 group F member 3 | C00010891 | 0 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00004588 | 0 / 0 |
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00000982 | 0 / 0 |
| Q9Y4X1 | UDP-glucuronosyltransferase 2A1 | Enzyme | C00000810 | 0 / 0 |
| O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | C00000982 | 0 / 0 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00005373 | 1 / 0 |
| P43166 | Carbonic anhydrase 7 | Lyase | C00002500 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00005373 | 0 / 0 |
| P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00003364 | 0 / 0 |
| P37059 | Estradiol 17-beta-dehydrogenase 2 | Enzyme | C00000982 | 0 / 0 |
| P00747 | Plasminogen | S1A | C00004638 | 1 / 2 |
| Q7Z2W7 | Transient receptor potential cation channel subfamily M member 8 | Unclassified protein | C00000810 | 0 / 0 |
| O60218 | Aldo-keto reductase family 1 member B10 | Enzyme | C00002751 | 0 / 0 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00010891 | 2 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00003364 | 1 / 1 |
| P19224 | UDP-glucuronosyltransferase 1-6 | Enzyme | C00000810 | 0 / 0 |
| Q9HAW8 | UDP-glucuronosyltransferase 1-10 | Enzyme | C00000982 | 0 / 0 |
| P08908 | 5-hydroxytryptamine receptor 1A | Serotonin receptor | C00005373 | 1 / 0 |
| P10275 | Androgen receptor | NR3C4 | C00000982 | 3 / 4 |
| Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00000982 | 0 / 0 |
| Q04760 | Lactoylglutathione lyase | Enzyme | C00000982 | 0 / 0 |
| P34949 | Mannose-6-phosphate isomerase | Enzyme | C00005373 | 1 / 1 |
| P49888 | Estrogen sulfotransferase | Enzyme | C00000982 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00005373 | 0 / 0 |
| O94956 | Solute carrier organic anion transporter family member 2B1 | Unclassified protein | C00000982 | 0 / 0 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00005373 | 0 / 0 |
| Q9Y6L6 | Solute carrier organic anion transporter family member 1B1 | Electrochemical transporter | C00000982 | 1 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00004588 | 1 / 0 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00005373 | 4 / 1 |
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00000982 | 0 / 0 |
| P33527 | Multidrug resistance-associated protein 1 | drugs | C00000982 | 0 / 0 |
| P14061 | Estradiol 17-beta-dehydrogenase 1 | Enzyme | C00000982 | 0 / 0 |
| Q00653 | Nuclear factor NF-kappa-B p100 subunit | Transcription Factor | C00003363 | 0 / 0 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00003363 | 0 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00005373 | 0 / 0 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00010891 | 1 / 1 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 4363 | ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
C00000982
|
| 10257 | ABCC4, EST170205, MOAT-B, MOATB, MRP4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
C00000982
|
| 10057 | ABCC5, ABC33, EST277145, MOAT-C, MOATC, MRP5, SMRP, pABC11 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 |
C00000982
|
| 196 | AHR, bHLHe76 | aryl hydrocarbon receptor |
C00000982
|
| 1645 | AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB | aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112) |
C00000982
|
| 8644 | AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS | aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357) |
C00000982
|
| 207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) |
C00000982
|
| 249 | ALPL, AP-TNAP, APTNAP, HOPS, TNAP, TNSALP | alkaline phosphatase, liver/bone/kidney (EC:3.1.3.1) |
C00000982
|
| 405 | ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2 | aryl hydrocarbon receptor nuclear translocator |
C00000982
|
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00000982
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00000982
|
| 842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00000982
|
| 1588 | CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM | cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00000982
|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00000982
|
| 1544 | CYP1A2, CP12, P3-450, P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) |
C00000982
|
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) |
C00000982
|
| 1559 | CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9 | cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) |
C00000982
|
| 1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) |
C00000982
|
| 2099 | ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 | estrogen receptor 1 |
C00000982
|
| 2100 | ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2 | estrogen receptor 2 (ER beta) |
C00000982
|
| 3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00000982
|
| 3757 | KCNH2, ERG1, HERG, HERG1, Kv11.1, LQT2, SQT1 | potassium voltage-gated channel, subfamily H (eag-related), member 2 |
C00000982
|
| 5444 | PON1, ESA, MVCD5, PON | paraoxonase 1 (EC:3.1.1.2 3.1.8.1 3.1.1.81) |
C00000982
|
| 6566 | SLC16A1, HHF7, MCT, MCT1 | solute carrier family 16 (monocarboxylate transporter), member 1 |
C00000982
|
| 6513 | SLC2A1, DYT17, DYT18, DYT9, EIG12, GLUT, GLUT1, GLUT1DS, HTLVR, PED | solute carrier family 2 (facilitated glucose transporter), member 1 |
C00000982
|
| 6817 | SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) |
C00000982
|
| 6818 | SULT1A3, HAST, HAST3, M-PST, ST1A3/ST1A4, ST1A5, STM, TL-PST | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 (EC:2.8.2.1) |
C00000982
|
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00000982
|
| 7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00000982
|
| 54658 | UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A | UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) |
C00000982
|
| 54575 | UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J | UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) |
C00000982
|
| 54577 | UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G | UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) |
C00000982
|
| 54576 | UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H | UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) |
C00000982
|
| 54600 | UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I | UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) |
C00000982
|
| 7366 | UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8 | UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17) |
C00000982
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
| #203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
| #606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #613546 | Aromatase deficiency |
P11511
|
| #139300 | Aromatase excess syndrome; aexs |
P11511
|
| #208900 | Ataxia-telangiectasia; at |
Q13315
|
| #601816 | Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 |
P22309
|
| #614490 | Blood group, junior system; jr |
Q9UNQ0
|
| %606641 | Body mass index; bmi |
P37231
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #609338 | Carotid intimal medial thickness 1 |
P37231
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #114500 | Colorectal cancer; crc |
P18054
P84022 |
| #602579 | Congenital disorder of glycosylation, type ib; cdg1b |
P34949
|
| #218800 | Crigler-najjar syndrome, type i |
P22309
P22310 |
| #606785 | Crigler-najjar syndrome, type ii |
P22309
P22310 |
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #237500 | Dubin-johnson syndrome; djs |
Q92887
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #615040 | Episodic pain syndrome, familial, 1; feps1 |
O75762
|
| #133239 | Esophageal cancer |
P18054
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #301500 | Fabry disease |
P06280
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #608013 | Gaucher disease, perinatal lethal |
P04062
|
| #230800 | Gaucher disease, type i |
P04062
|
| #230900 | Gaucher disease, type ii |
P04062
|
| #231000 | Gaucher disease, type iii |
P04062
|
| #231005 | Gaucher disease, type iiic |
P04062
|
| #143500 | Gilbert syndrome |
P22309
P22310 |
| #137750 | Glaucoma 1, open angle, a; glc1a |
Q16678
|
| #231300 | Glaucoma 3, primary congenital, a; glc3a |
Q16678
|
| #137760 | Glaucoma, primary open angle; poag |
Q16678
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
P37231 |
| #232300 | Glycogen storage disease ii |
P10253
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #237450 | Hyperbilirubinemia, rotor type; hblrr |
Q9NPD5
Q9Y6L6 |
| #237900 | Hyperbilirubinemia, transient familial neonatal; hblrtfn |
P22309
|
| #143860 | Hyperchlorhidrosis, isolated |
O43570
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #146300 | Hypophosphatasia, adult |
P05186
|
| #241510 | Hypophosphatasia, childhood |
P05186
|
| #241500 | Hypophosphatasia, infantile |
P05186
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #601626 | Leukemia, acute myeloid; aml |
P36888
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #601665 | Obesity |
P37231
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #168600 | Parkinson disease, late-onset; pd |
P04062
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #614674 | Periodic fever, menstrual cycle-dependent |
P08908
|
| #604229 | Peters anomaly |
Q16678
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #217090 | Plasminogen deficiency, type i |
P00747
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #138900 | Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 |
Q9UNQ0
|
| #614916 | Ventricular tachycardia, catecholaminergic polymorphic, 4; cpvt4 |
P62158
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #278300 | Xanthinuria, type i |
P47989
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
| #112100 | Yt blood group antigen |
P22303
|
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H01302 | Hyperchlorhidrosis isolated (HCHLH) |
O43570
(related)
|
| H00021 | Renal cell carcinoma |
O43570
(marker)
Q16790 (marker) |
| H00223 | Inherited thrombophilia |
P00747
(related)
|
| H01206 | Plasminogen deficiency |
P00747
(related)
|
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
P37231 (related) |
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
Q92731 (marker) |
| H00066 | Lewy body dementia (LBD) |
P04062
(related)
|
| H00126 | Gaucher disease |
P04062
(related)
|
| H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
| H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
P11511 (related) |
| H00213 | Hypophosphatasia |
P05186
(related)
|
| H00125 | Fabry disease |
P06280
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
| H00024 | Prostate cancer |
P10275
(related)
|
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00023 | Testicular cancer |
P10696
(marker)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00794 | Aromatase excess syndrome |
P11511
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
| H00038 | Malignant melanoma |
P14679
(marker)
|
| H00208 | Hyperbilirubinemia |
P22309
(related)
Q92887 (related) |
| H00018 | Gastric cancer |
P24864
(related)
|
| H00055 | Laryngeal cancer |
P24864
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00118 | Congenital disorders of glycosylation (CDG) type I |
P34949
(related)
|
| H00017 | Esophageal cancer |
P35354
(related)
|
| H00025 | Penile cancer |
P35354
(related)
|
| H00046 | Cholangiocarcinoma |
P35354
(related)
|
| H00003 | Acute myeloid leukemia (AML) |
P36888
(related)
Q01196 (related) Q01196 (marker) Q13951 (marker) |
| H00032 | Thyroid cancer |
P37231
(related)
|
| H00409 | Type II diabetes mellitus |
P37231
(related)
|
| H00192 | Xanthinuria |
P47989
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
Q13315
(related)
|
| H00064 | Ataxia telangiectasia (AT) |
Q13315
(related)
|
| H00094 | DNA repair defects |
Q13315
(related)
|
| H00848 | Ataxia with ocular apraxia (AOA) |
Q13315
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00612 | Primary open angle glaucoma |
Q16678
(related)
|
| H01075 | Peters anomaly |
Q16678
(related)
|
| H01159 | Anterior segment dysgenesis (ASD) |
Q16678
(related)
|
| H01203 | Primary congenital glaucoma (PCG) |
Q16678
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
Q9NUW8 (related) |
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D000647 | Amnesia |
C00000982
|
| D001932 | Brain Neoplasms |
C00000982
|
| D009202 | Cardiomyopathies |
C00000982
|
| D056486 | Drug-Induced Liver Injury |
C00000982
|
| D064420 | Drug-Related Side Effects and Adverse Reactions |
C00000982
|
| D007674 | Kidney Diseases |
C00000982
|
| D008106 | Liver Cirrhosis, Experimental |
C00000982
|
| D008107 | Liver Diseases |
C00000982
|
| D009369 | Neoplasms |
C00000982
|
| D009374 | Neoplasms, Experimental |
C00000982
|