Entry
Symbol
pnp, PNPT1
Name
polyribonucleotide nucleotidyltransferase [EC:
2.7.7.8 ]
Pathway
Disease
H00063 Spinocerebellar ataxia (SCA)
H00605 Deafness, autosomal recessive
H00891 Combined oxidative phosphorylation deficiency
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03018 RNA degradation
K00962 pnp, PNPT1; polyribonucleotide nucleotidyltransferase
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis
K00962 pnp, PNPT1; polyribonucleotide nucleotidyltransferase
03016 Transfer RNA biogenesis
K00962 pnp, PNPT1; polyribonucleotide nucleotidyltransferase
Enzymes [BR:ko01000 ]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.7 Nucleotidyltransferases
2.7.7.8 polyribonucleotide nucleotidyltransferase
K00962 pnp, PNPT1; polyribonucleotide nucleotidyltransferase
Messenger RNA biogenesis [BR:ko03019 ]
Prokaryotic type
Bacterial mRNA degradation factors
RNA degradosome components
Other RNA degradosome components
K00962 pnp, PNPT1; polyribonucleotide nucleotidyltransferase
Transfer RNA biogenesis [BR:ko03016 ]
Prokaryotic type
tRNA degradation factors
K00962 pnp, PNPT1; polyribonucleotide nucleotidyltransferase
BRITE hierarchy
Other DBs
Genes
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Taxonomy UniProt
Reference
Authors
Carpousis AJ
Title
The RNA degradosome of Escherichia coli: an mRNA-degrading machine assembled on RNase E.
Journal
Sequence
Reference
Authors
Marcaida MJ, DePristo MA, Chandran V, Carpousis AJ, Luisi BF
Title
The RNA degradosome: life in the fast lane of adaptive molecular evolution.
Journal
Sequence
Reference
Authors
Portnoy V, Palnizky G, Yehudai-Resheff S, Glaser F, Schuster G
Title
Analysis of the human polynucleotide phosphorylase (PNPase) reveals differences in RNA binding and response to phosphate compared to its bacterial and chloroplast counterparts.
Journal
Sequence