Thuja plicata

• Index
• Plant Species
• Metabolite list (19)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Thuja plicata
Genus	Thuja
Family	Cupressaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Thuja plicata
Linked NCBI taxonomy ID	3316
Linked level	species

Family

Family in NCBI taxonomy	Cupressaceae
ID	3367

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	Spermatophyta
ID	58024

Metabolite list (19)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00008711	Taxifolin 3'-glucoside					No. 12	No. 14
C00000587	(-)-Pinoresinol	CHEMBL267963 CHEMBL487611 CHEMBL460862		7 / 5 / 6		No. 38	No. 21
C00006614	Cyanidin	CHEMBL404515		3 / 0 / 4		No. 71	No. 15
C00002598	Yatein / (-)-Yatein / (-)-Deoxypodorhizone / Dihydroanhydropodorhizol	CHEMBL345590 CHEMBL471067 CHEMBL2021357	C452802	2 / 1 / 1		No. 223	No. 21
C00000605	(+)-Secoisolariciresinol	CHEMBL368347		2 / 1 / 1		No. 282	No. 21
C00000604	(-)-Secoisolariciresinol	CHEMBL368347	C060283	2 / 1 / 1	1 / 0	No. 282	No. 21
C00031398	Sugiol / (+)-Sugiol	CHEMBL195296				No. 355
C00011058	(-)-alpha-Fenchene / (-)-7,7-dimethyl-2-methylenenorbornane					No. 476	No. 35
C00000636	(+)-Pinoresinolin					No. 621	No. 21
C00000603	(-)-Lariciresinol	CHEMBL518421	C060282	2 / 1 / 1		No. 700	No. 21
C00000836	cis-Thujone / (+)-Thujone / beta-Thujone	CHEMBL1444078		2 / 3 / 2		No. 1161	No. 35
C00000804	(-)-3-Isothujone / (-)-alpha-Thujone	CHEMBL1444078		2 / 3 / 2		No. 1161	No. 35
C00034795	alpha-Thujone	CHEMBL1444078		2 / 3 / 2		No. 1161	No. 35
C00003062	beta-Thujaplicin	CHEMBL48310	C009479	27 / 27 / 50		No. 1304	No. 35
C00011011	alpha-Thujaplicin / 2-Hydroxy-3-isopropyl-2,4,6-cycloheptatrien-1-one	CHEMBL1275969				No. 1304	No. 35
C00003063	gamma-Thujaplicin	CHEMBL1275999				No. 1304	No. 35
C00011007	5,5-Dimethyl-1,3,6-cycloheptatriene-1-carboxylic acid		C003462			No. 4302
C00011009	beta-Dolabrin		C410956			No. 4728
C00000634	Plicatic acid		C008938			No. 7392	No. 21

Human Protein / Gene in interactions

36 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000603 C00000604 C00000605 C00002598 C00003062	0 / 1
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000603 C00000604 C00000605 C00002598	1 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00000804 C00000836 C00003062 C00034795	0 / 0
P16473	Thyrotropin receptor	Glycohormone receptor	C00000804 C00000836 C00034795	3 / 2
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00000587 C00006614	0 / 3
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00000587 C00003062	0 / 0
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00000587 C00003062	0 / 0
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00000587	5 / 3
P14780	Matrix metalloproteinase-9	M10A	C00003062	2 / 2
P28907	ADP-ribosyl cyclase 1	Enzyme	C00006614	0 / 1
P22894	Neutrophil collagenase	M10A	C00003062	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00003062	2 / 3
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00006614	0 / 0
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00003062	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00003062	0 / 0
P42858	Huntingtin	Unclassified protein	C00003062	1 / 1
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00003062	0 / 0
P03956	Interstitial collagenase	M10A	C00003062	0 / 1
Q16637	Survival motor neuron protein	Unclassified protein	C00003062	4 / 1
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00000587	0 / 0
P18054	Arachidonate 12-lipoxygenase, 12S-type	Enzyme	C00003062	2 / 0
P08253	72 kDa type IV collagenase	M10A	C00003062	1 / 3
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00003062	2 / 2
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00003062	0 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00003062	0 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00003062	7 / 37
P10636	Microtubule-associated protein tau	Unclassified protein	C00003062	4 / 3
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00003062	0 / 0
Q07869	Peroxisome proliferator-activated receptor alpha	NR1C1	C00000587	0 / 0
P08254	Stromelysin-1	M10A	C00003062	1 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00003062	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00003062	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00003062	1 / 1
Q8IUX4	DNA dC->dU-editing enzyme APOBEC-3F	Enzyme	C00003062	0 / 0
Q9H0H5	Rac GTPase-activating protein 1	Unclassified protein	C00000587	0 / 0
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00003062	1 / 1

1 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
8856	NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR	nuclear receptor subfamily 1, group I, member 2	C00000604

Related Diseases

Diseases related to proteins in ChEMBL interactions