Species

KNApSAcK Entry

Organism name Erythrina sigmoidea
Genus Erythrina
Family Fabaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Erythrina
Linked NCBI taxonomy ID 3841
Linked level genus

Family

Family in NCBI taxonomy Fabaceae
ID 3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (22)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00009516 External link 512 6,8-Diprenylgenistein
/ 8-(gamma,gamma-Dimethylallyl)wighteone
/ 5,7,4'-Trihydroxy-6,8-diprenylisoflavone
CHEMBL494252
12 / 14 / 11 No. 14 No. 15
C00009432 External link 512 Neobavaisoflavone
CHEMBL512693
1 / 0 / 0 No. 15 No. 15
C00009514 External link 512 Scandenone
/ Warangalone
CHEMBL458134
C105205
No. 18 No. 15
C00008319 External link 512 Sigmoidin A
CHEMBL229506
C064221
1 / 0 / 0 No. 19 No. 14
C00000936 External link 512 Abyssinone V
CHEMBL255890
CHEMBL454332
C056679
2 / 0 / 0 No. 19 No. 14
C00008202 External link 512 Abyssinone IV
CHEMBL470454
1 / 0 / 0 No. 19 No. 14
C00009430 External link 512 Corylin
CHEMBL1271888
No. 24 No. 15
C00018968 External link 512 Sigmoidin J
/ 7,4'-Dihydroxy-2',5'-dimethoxy-6-prenylisoflavanone
C090619
No. 28 No. 14
C00008318 External link 512 Sigmoidin B
CHEMBL229454
C064222
1 / 0 / 0 No. 28 No. 14
C00019595 External link 512 Sigmoidin I
/ 7,4'-Dihydroxy-2'-methoxy-5'-prenylisoflavanone
No. 28 No. 14
C00008465 External link 512 Sigmoidin F
CHEMBL229222
C062901
1 / 0 / 0 No. 39
C00019597 External link 512 4-Hydroxycoumestrol
/ 3,4,9-Trihydroxycoumestan
No. 54 No. 17
C00019596 External link 512 Sigmoidin H
/ 7-Hydroxy-2'-methoxy-6'',6''-dimethylpyrano[2'',3'':4',5']isoflavanone
No. 127 No. 14
C00008320 External link 512 Sigmoidin C
CHEMBL229617
1 / 0 / 0 No. 127 No. 14
C00002559 External link 512 Phaseolin
/ (-)-Phaseollin
CHEMBL448350
No. 135 No. 15
C00002558 External link 512 Phaseollidin
CHEMBL508534
C085158
1 / 0 / 0 No. 188 No. 15
C00002371 External link 512 Abyssinone VI
CHEMBL508727
1 / 0 / 0 No. 190 No. 13
C00001852 External link 512 Erythratidine
No. 273 No. 4
C00018969 External link 512 Sigmoidin K
/ 3,9-Dihydroxy-2,10-diprenylcoumestan
CHEMBL1095262
C090620
No. 436 No. 17
C00009669 External link 512 Erythrabyssin II
/ 3,9-Dihydroxy-2,10-diprenylpterocarpan
CHEMBL455372
1 / 0 / 0 No. 460
C00008457 External link 512 Sigmoidin D
CHEMBL516331
C051738
1 / 0 / 0 No. 740
C00008516 External link 512 Sigmoidin G
No. 740

Human Protein / Gene in interactions

15 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr C00000936 C00002371 C00002558 C00008202 C00008318 C00008319 C00008320 C00008457 C00008465 C00009669 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00009516 0 / 0
P04062 Glucosylceramidase Enzyme C00009516 6 / 4
P11388 DNA topoisomerase 2-alpha Isomerase C00009432 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00009516 2 / 0
O75496 Geminin Unclassified protein C00009516 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00009516 0 / 0
Q99700 Ataxin-2 Unclassified protein C00009516 1 / 1
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00009516 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00009516 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00009516 4 / 3
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00009516 0 / 0
P04054 Phospholipase A2 Enzyme C00000936 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00009516 1 / 0
P01215 Glycoprotein hormones alpha chain Unclassified protein C00009516 0 / 3

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (14)

OMIM preferred title UniProt
#114500 Colorectal cancer; crc P84022
#600274 Frontotemporal dementia; ftd P10636
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#137800 Glioma susceptibility 1; glm1 O75874
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#168600 Parkinson disease, late-onset; pd P04062
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (11)

KEGG name UniProt
H00081 Hashimoto's thyroiditis P01215 (marker)
H00082 Graves' disease P01215 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P01215 (marker)
H00066 Lewy body dementia (LBD) P04062 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)