Xylopia parviflora

• Index
• Plant Species
• Metabolite list (47)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Xylopia parviflora
Genus	Xylopia
Family	Annonaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Xylopia parviflora
Linked NCBI taxonomy ID	992813
Linked level	species

Family

Family in NCBI taxonomy	Annonaceae
ID	22140

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	Magnoliophyta
ID	3398

Metabolite list (47)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00001806	Anolobine / (-)-Anolobine	CHEMBL257746				No. 20	No. 4
C00001807	Anonaine / (-)-Anonaine / (R)-Annonaine	CHEMBL401798	C098138	1 / 0 / 0		No. 20	No. 4
C00034986	(+)-Noroconovine					No. 20	No. 4
C00034984	(+)-10,11-Dihydroxy-1,2-dimethoxynoraporphine					No. 20	No. 4
C00034982	(+)-1,2-Dimethoxy-3-hydroxy-9,10-methylenedioxynoraporphine	CHEMBL1618043				No. 20	No. 4
C00027433	Laurolitsine / (+)-Norboldine / (+)-Laurolitsine	CHEMBL487388	C109133			No. 20	No. 4
C00027409	Laurotetanin / Laurotetanine / (+)-Laurotetanine	CHEMBL464098	C008256			No. 20	No. 4
C00027307	Calycinine / (-)-Calycinine	CHEMBL226824				No. 20	No. 4
C00025676	Norglaucin / Norglaucine / (+)-Norglaucine / O,O-Dimethyllaurelliptine					No. 20	No. 4
C00025675	Lauroscholtzine / 2-O-Methylboldine / N-Methyllaurotetanine / (+)-N-Methyllaurotetanine	CHEMBL464099		1 / 1 / 0		No. 20	No. 4
C00025269	Nornantenine / N-Nornantenine / (+)-Nornantenine	CHEMBL1254951		1 / 0 / 0		No. 20	No. 4
C00027304	Boldine / d-Boldine / (+)-Boldine	CHEMBL388342 CHEMBL1321247 CHEMBL1437753	C011686	34 / 32 / 35		No. 20	No. 4
C00025655	Corytuberine / (+)-Corytuberine	CHEMBL227965	C013896	1 / 0 / 0		No. 20	No. 4
C00001928	Xylopine / (-)-Xylopine	CHEMBL227689 CHEMBL452201	C062700			No. 20	No. 4
C00025402	Norargemonine / (-)-Norargemonine / O2-Demetylargemonie / O8-Demethylargemonine	CHEMBL1570385		2 / 2 / 0		No. 37	No. 4
C00025397	Rotundine / (-)-Bisnorargemonine	CHEMBL518908 CHEMBL1494954		1 / 0 / 0		No. 37	No. 4
C00025238	Discretine / (-)-Discretine	CHEMBL513084				No. 37	No. 4
C00025930	Lindoldhamine / (+)-Lindoldhamine	CHEMBL1375576		9 / 8 / 11		No. 89	No. 4
C00027137	Dehydrocoreximine					No. 155	No. 4
C00001874	Neprotin / Neprotine / Yatrorizine / Jatrorrhizine	CHEMBL251055	C055785	14 / 27 / 20	1 / 0	No. 155	No. 4
C00026127	Dehydrodiscretine / Pseudojatrorrhizine	CHEMBL220527				No. 155	No. 4
C00027159	Depiline / Palmatine / Berbericinine / O,O-Dimethyldemethyleneberberine	CHEMBL206106	C005413	8 / 13 / 13	8 / 0	No. 155	No. 4
C00027160	Phellodendrine		C079418			No. 234
C00034979	(-)-4'-O-Methylcoclaurine	CHEMBL451723				No. 253	No. 4
C00025652	d-Coclaurine / Sanjoinine K / (R)-Coclaurine / (+)-Coclaurine / (+)-R-Coclaurine	CHEMBL256448 CHEMBL453291 CHEMBL446211		8 / 17 / 10		No. 253	No. 4
C00025619	(-)-N-Methylcoclaurine / (R)-N-Methylcoclaurine	CHEMBL453292 CHEMBL513109				No. 253	No. 4
C00001885	Escholin / Escholine / Thalictrin / Thalictrine / Magnoflorine / (+)-Magnoflorine	CHEMBL235428	C001670			No. 286	No. 4
C00027170	Xanthoplanine / (+)-Xanthoplanine	CHEMBL1180065				No. 286	No. 4
C00025674	N-Methylcorydine / (+)-N-Methylcorydine	CHEMBL1617951				No. 286	No. 4
C00027152	N-Methylphoebine					No. 286	No. 4
C00025654	Codamine / (+)-Codamine / L-(+)-Codamine / (S)-(+)-Codamine	CHEMBL251624				No. 345	No. 4
C00025666	(S)-Laudanine / (+)-Laudanidine / L-(+)-Laudanidine	CHEMBL251625 CHEMBL1425007		2 / 0 / 0		No. 345	No. 4
C00034987	(+)-Parvinine	CHEMBL452500				No. 345	No. 4
C00001910	Reticuline / (+)-Reticuline	CHEMBL235212 CHEMBL401501 CHEMBL464734	C003298	1 / 0 / 0		No. 345	No. 4
C00026017	Protosinomenine / (S)-Protosinomenine					No. 345	No. 4
C00001862	Glaziovine / L-Glaziovine / N-Methylcrotsparine / L-(-)-N-Methylcrotsparine	CHEMBL1980854	C007847			No. 688
C00025272	Stepharine / (+)-Stepharine	CHEMBL463957 CHEMBL1975436	C009320			No. 688
C00025934	Lotusine / (-)-Lotusine / D-(-)-Lotusine					No. 896
C00025982	Oblongine / (+)-Oblongine	CHEMBL457373	C081049			No. 896
C00025347	Tembetarine / (+)-Tembetarine		C003383			No. 896
C00035166	Yuzirine		C417577			No. 1137
C00027167	Thalifoline	CHEMBL1813177				No. 2199
C00027111	1,2-Dehydroreticuline					No. 2440
C00001879	Longifolonine					No. 3542
C00001815	Backebergine					No. 4224
C00026021	Pycnarrhine / Dehydrocorypalline	CHEMBL1618006				No. 4925
C00027140	Dihydrobackebergine / 3,4-Dihydrobackebergine / 3,4-Dihydro-6,7-dimethoxyisoquinoline / 6,7-Dimethoxy-3,4-dihydroisoquinoline	CHEMBL1998359				No. 4925

Human Protein / Gene in interactions

49 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
O75496	Geminin	Unclassified protein	C00025402 C00025652 C00025666 C00027304	0 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00001874 C00025397 C00025652 C00025666	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00001874 C00025652 C00025930 C00027304	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00001874 C00025652 C00025930 C00027304	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00001874 C00025652 C00025930 C00027304	4 / 3
P02545	Prelamin-A/C	Unclassified protein	C00001874 C00027159 C00027304	11 / 10
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00001874 C00027159 C00027304	0 / 1
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00027159 C00027304	0 / 1
P04062	Glucosylceramidase	Enzyme	C00001874 C00025652	6 / 4
P14618	Pyruvate kinase PKM	Enzyme	C00025652 C00025930	0 / 0
O00255	Menin	Unclassified protein	C00025930 C00027304	2 / 5
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00001874 C00027304	1 / 1
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00025930 C00027304	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00001874 C00027304	0 / 0
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00001874 C00027304	1 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00025930 C00027304	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00027159 C00027304	1 / 1
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00027159 C00027304	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00001874 C00027304	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00027159 C00027304	0 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00025930 C00027304	1 / 2
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00027159 C00027304	1 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00027304	1 / 1
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00025652	7 / 3
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00027304	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00025402	2 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00027159	0 / 0
P36544	Neuronal acetylcholine receptor subunit alpha-7	CHRN alpha	C00027304	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00027304	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00027304	3 / 3
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00027304	2 / 2
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00027304	0 / 0
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00025269	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00001910	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00027304	0 / 0
Q14761	Protein tyrosine phosphatase receptor type C-associated protein	Enzyme	C00001807	0 / 0
P43681	Neuronal acetylcholine receptor subunit alpha-4	CHRN alpha	C00027304	1 / 1
P17787	Neuronal acetylcholine receptor subunit beta-2	CHRN beta	C00027304	1 / 1
P24941	Cyclin-dependent kinase 2	Cdc2	C00025655	0 / 0
P08908	5-hydroxytryptamine receptor 1A	Serotonin receptor	C00025675	1 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00027304	0 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00027304	0 / 0
P06746	DNA polymerase beta	Enzyme	C00001874	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00025930	1 / 1
Q99700	Ataxin-2	Unclassified protein	C00027304	1 / 1
Q13951	Core-binding factor subunit beta	Unclassified protein	C00027304	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00027304	1 / 4
Q16637	Survival motor neuron protein	Unclassified protein	C00001874	4 / 1
P43351	DNA repair protein RAD52 homolog	Unclassified protein	C00001874	0 / 0

8 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
332	BIRC5, API4, EPR-1	baculoviral IAP repeat containing 5	C00001874 C00027159
6352	CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP	chemokine (C-C motif) ligand 5	C00027159
6348	CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3	chemokine (C-C motif) ligand 3	C00027159
6351	CCL4, ACT2, AT744.1, G-26, HC21, LAG-1, LAG1, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4	chemokine (C-C motif) ligand 4	C00027159
6347	CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF	chemokine (C-C motif) ligand 2	C00027159
3570	IL6R, CD126, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ, gp80	interleukin 6 receptor	C00027159
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00027159
7422	VEGFA, MVCD1, VEGF, VPF	vascular endothelial growth factor A	C00027159

Related Diseases

Diseases related to proteins in ChEMBL interactions