Species

KNApSAcK Entry

Organism name Arachis hypogaea
Genus Arachis
Family Fabaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Arachis hypogaea
Linked NCBI taxonomy ID 3818
Linked level species

Family

Family in NCBI taxonomy Fabaceae
ID 3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (18)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00001029 External link 512 Chrysoeriol
/ Luteolin 3'-methyl ether
CHEMBL214321
C007054
20 / 24 / 20 8 / 0 No. 3 No. 15
C00000256 External link 512 Soyasapogenol B
CHEMBL153969
CHEMBL1762007
C407096
1 / 0 / 0 No. 13 No. 51
C00009071 External link 512 Procyanidin B3
/ Catechin-(4alpha->8)-catechin
CHEMBL38714
CHEMBL81753
CHEMBL504937
CHEMBL501490
CHEMBL447373
CHEMBL1253314
CHEMBL1590914
20 / 7 / 8 No. 16 No. 19
C00002935 External link 512 Procyanidin B4
/ Catechin-(4alpha->8)-epicatechin
CHEMBL38714
CHEMBL81753
CHEMBL504937
CHEMBL501490
CHEMBL447373
CHEMBL1253314
CHEMBL1590914
20 / 7 / 8 No. 16 No. 19
C00009077 External link 512 Procyanidin B2
/ Epicathechin-(4beta->8)-epicathechin
CHEMBL38714
CHEMBL81753
CHEMBL504937
CHEMBL501490
CHEMBL447373
CHEMBL1253314
CHEMBL1590914
C479580
20 / 7 / 8 10 / 0 No. 16 No. 19
C00000960 External link 512 Eriodictyol
CHEMBL8996
CHEMBL307893
CHEMBL1975989
C007619
32 / 29 / 55 5 / 0 No. 25 No. 14
C00009451 External link 512 5,7-Dimethoxyisoflavone
CHEMBL308688
9 / 23 / 47 No. 35 No. 15
C00000947 External link 512 D-Catechol
/ D-Catechin
/ Teafuran 30A
/ (+)-Catechin
/ Dexcyanidanol
/ (+)-3',4',5,7-Tetrahydroxy-2,3-trans-flavan-3-ol
CHEMBL80941
CHEMBL311498
CHEMBL129482
CHEMBL200715
CHEMBL206452
CHEMBL583912
D002392
85 / 58 / 54 91 / 13 No. 52 No. 14
C00009814 External link 512 5,7-Dihydroxyisoflavone
CHEMBL1488393
21 / 32 / 59 No. 71 No. 15
C00001209 External link 512 Arachidic acid
/ Eicosanoic acid
CHEMBL1173381
C094477
No. 184 No. 68
C00000615 External link 512 Caffeic acid
CHEMBL145
CHEMBL1320034
68 / 64 / 63 No. 904 No. 6
C00002901 External link 512 Arachidin II
/ 4-Prenylresveratrol
/ 4-Isopentenyl-3,4',5-trihydroxystilbene
No. 1271 No. 13
C00015901 External link 512 3-Isopentadienyl-3',4,5'-trihydroxystilbene
No. 1951
C00001200 External link 512 Pyruvic acid
CHEMBL1162144
D019289
5 / 2 / 2 10 / 4 No. 2782
C00002422 External link 512 5,7-Dihydroxychromone
/ 5,7-Dihydroxy-4-chromone
C080094
No. 3998 No. 15
C00001431 External link 512 Spermidine
CHEMBL19612
D013095
26 / 10 / 12 5 / 5 No. 5867
C00001432 External link 512 Spermine
CHEMBL23194
D013096
35 / 17 / 25 7 / 11 No. 7197
C00001186 External link 512 Glyoxylic acid
CHEMBL1162545
C031150
1 / 0 / 0 0 / 1 No. 7855

Human Protein / Gene in interactions

157 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00000615 C00000947 C00000960 C00001431 C00001432 C00002935 C00009071 C00009077 C00009451 C00009814 0 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00000615 C00000947 C00000960 C00001029 C00001431 C00001432 C00002935 C00009071 C00009077 0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00000615 C00000947 C00000960 C00001432 C00002935 C00009071 C00009077 C00009451 C00009814 3 / 3
P16050 Arachidonate 15-lipoxygenase Enzyme C00000947 C00000960 C00001431 C00001432 C00002935 C00009071 C00009077 C00009814 0 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00000615 C00000947 C00001431 C00001432 C00002935 C00009071 C00009077 1 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00000615 C00000947 C00001431 C00001432 C00002935 C00009071 C00009077 0 / 1
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00000615 C00000947 C00001431 C00001432 C00002935 C00009071 C00009077 1 / 1
P00352 Retinal dehydrogenase 1 Enzyme C00000615 C00000947 C00000960 C00001029 C00009451 C00009814 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00000615 C00000947 C00000960 C00001029 C00009451 C00009814 4 / 3
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00000615 C00000947 C00000960 C00009451 C00009814 2 / 2
O00255 Menin Unclassified protein C00000615 C00000947 C00001029 C00001432 C00009814 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00000615 C00000947 C00001029 C00001432 C00009814 1 / 2
P05129 Protein kinase C gamma type Alpha C00000947 C00002935 C00009071 C00009077 1 / 1
Q05655 Protein kinase C delta type Delta C00000947 C00002935 C00009071 C00009077 0 / 0
P00915 Carbonic anhydrase 1 Lyase C00000615 C00000947 C00001431 C00001432 0 / 0
P17252 Protein kinase C alpha type Alpha C00000947 C00002935 C00009071 C00009077 0 / 0
Q16790 Carbonic anhydrase 9 Lyase C00000615 C00000947 C00001431 C00001432 0 / 1
P06746 DNA polymerase beta Enzyme C00000615 C00000947 C00000960 C00001029 0 / 0
O94806 Serine/threonine-protein kinase D3 Pkd C00000947 C00002935 C00009071 C00009077 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00000615 C00000947 C00000960 C00009814 0 / 0
P05771 Protein kinase C beta type Alpha C00000947 C00002935 C00009071 C00009077 0 / 0
P35218 Carbonic anhydrase 5A, mitochondrial Lyase C00000615 C00000947 C00001431 C00001432 0 / 0
P43166 Carbonic anhydrase 7 Lyase C00000615 C00000947 C00001431 C00001432 0 / 0
Q02156 Protein kinase C epsilon type Eta C00000947 C00002935 C00009071 C00009077 0 / 0
Q04759 Protein kinase C theta type Delta C00000947 C00002935 C00009071 C00009077 0 / 1
Q05513 Protein kinase C zeta type Iota C00000947 C00002935 C00009071 C00009077 0 / 0
O43570 Carbonic anhydrase 12 Lyase C00000615 C00000947 C00001431 C00001432 1 / 2
Q9ULX7 Carbonic anhydrase 14 Lyase C00000615 C00000947 C00001431 C00001432 0 / 0
P24723 Protein kinase C eta type Eta C00000947 C00002935 C00009071 C00009077 1 / 0
P23280 Carbonic anhydrase 6 Lyase C00000615 C00000947 C00001431 C00001432 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00000615 C00000947 C00001431 C00001432 0 / 0
Q15139 Serine/threonine-protein kinase D1 Pkd C00000947 C00002935 C00009071 C00009077 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00000615 C00000947 C00000960 C00009814 0 / 0
P41743 Protein kinase C iota type Iota C00000947 C00002935 C00009071 C00009077 0 / 0
P07451 Carbonic anhydrase 3 Lyase C00000615 C00000947 C00001431 C00001432 0 / 0
P22748 Carbonic anhydrase 4 Lyase C00000615 C00000947 C00001431 C00001432 1 / 1
B2RXH2 Lysine-specific demethylase 4E Enzyme C00000615 C00000947 C00000960 C00009451 0 / 0
P00918 Carbonic anhydrase 2 Lyase C00000615 C00000947 C00001431 C00001432 1 / 2
Q9Y2D0 Carbonic anhydrase 5B, mitochondrial Lyase C00000615 C00000947 C00001431 C00001432 0 / 0
P16473 Thyrotropin receptor Glycohormone receptor C00000615 C00000947 C00001431 3 / 2
P18433 Receptor-type tyrosine-protein phosphatase alpha Receptor tyrosine-protein phosphatase C00002935 C00009071 C00009077 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00000615 C00000947 C00000960 0 / 0
O75496 Geminin Unclassified protein C00000256 C00000960 C00001029 0 / 0
P39748 Flap endonuclease 1 Enzyme C00000947 C00000960 C00001029 0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme C00000947 C00000960 C00001432 0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase C00000615 C00000947 C00000960 1 / 1
O15296 Arachidonate 15-lipoxygenase B Enzyme C00000960 C00001431 C00001432 0 / 0
P23467 Receptor-type tyrosine-protein phosphatase beta Receptor tyrosine-protein phosphatase C00002935 C00009071 C00009077 0 / 0
Q16637 Survival motor neuron protein Unclassified protein C00000947 C00009451 C00009814 4 / 1
P04637 Cellular tumor antigen p53 Transcription Factor C00000960 C00009451 C00009814 7 / 37
Q01196 Runt-related transcription factor 1 Unclassified protein C00001432 C00009814 1 / 4
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00000615 C00000947 0 / 0
P40225 Thrombopoietin Unclassified protein C00001431 C00001432 1 / 1
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00000615 C00000947 1 / 1
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor C00000615 C00000947 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00000947 C00000960 0 / 0
P54132 Bloom syndrome protein Enzyme C00000947 C00009814 1 / 2
Q13951 Core-binding factor subunit beta Unclassified protein C00001432 C00009814 0 / 1
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr C00000615 C00000947 0 / 0
P11473 Vitamin D3 receptor NR1I1 C00000947 C00009814 2 / 3
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00001029 C00001431 0 / 0
Q01453 Peripheral myelin protein 22 Unclassified protein C00000615 C00000947 5 / 2
O15427 Monocarboxylate transporter 4 Unclassified protein C00001186 C00001200 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00000615 C00000960 0 / 0
P04798 Cytochrome P450 1A1 Cytochrome P450 1A1 C00000960 C00001029 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00001431 C00009814 0 / 0
Q13093 Platelet-activating factor acetylhydrolase Enzyme C00000615 C00000947 3 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00000947 C00001029 2 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00000615 C00000947 0 / 0
P38398 Breast cancer type 1 susceptibility protein Enzyme C00001029 C00009814 4 / 2
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00000615 C00000960 0 / 0
P10696 Alkaline phosphatase, placental-like Enzyme C00000947 C00000960 0 / 1
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00000615 C00000947 0 / 3
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase C00000615 C00000947 1 / 1
P10828 Thyroid hormone receptor beta NR1A2 C00000615 C00009451 3 / 1
Q16678 Cytochrome P450 1B1 Cytochrome P450 1B1 C00000960 C00001029 4 / 4
Q9Y253 DNA polymerase eta Enzyme C00000947 C00000960 1 / 1
P09923 Intestinal-type alkaline phosphatase Enzyme C00000947 C00000960 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00000947 C00009814 0 / 0
Q9H015 Solute carrier family 22 member 4 Unclassified protein C00001431 C00001432 1 / 1
P05186 Alkaline phosphatase, tissue-nonspecific isozyme Enzyme C00000947 C00000960 3 / 1
P11021 78 kDa glucose-regulated protein Unclassified protein C00000960 0 / 0
P00734 Prothrombin S1A C00000947 4 / 2
P14679 Tyrosinase Oxidoreductase C00000615 4 / 2
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 C00001029 5 / 3
P03956 Interstitial collagenase M10A C00000615 0 / 1
P06280 Alpha-galactosidase A Enzyme C00000615 1 / 1
P04745 Alpha-amylase 1 Enzyme C00000947 0 / 0
P18054 Arachidonate 12-lipoxygenase, 12S-type Enzyme C00009814 2 / 0
P07711 Cathepsin L1 C1A C00000947 0 / 0
P08581 Hepatocyte growth factor receptor TK tyrosine-protein kinase MET subfamily C00000947 2 / 3
P35236 Tyrosine-protein phosphatase non-receptor type 7 Tyr C00000615 0 / 0
Q6QHF9 Peroxisomal N(1)-acetyl-spermine/spermidine oxidase Enzyme C00001431 0 / 0
P15121 Aldose reductase Enzyme C00000615 0 / 0
P56817 Beta-secretase 1 A1A C00000947 0 / 0
P41143 Delta-type opioid receptor Opioid receptor C00000947 0 / 0
P07998 Ribonuclease pancreatic Enzyme C00000947 0 / 0
P08253 72 kDa type IV collagenase M10A C00000615 1 / 3
Q8TDS4 Hydroxycarboxylic acid receptor 2 Hydroxycarboxylic acid receptor C00000615 0 / 0
Q92887 Canalicular multispecific organic anion transporter 1 Unclassified protein C00001029 1 / 1
Q04828 Aldo-keto reductase family 1 member C1 Enzyme C00000615 0 / 0
P42330 Aldo-keto reductase family 1 member C3 Enzyme C00000615 0 / 0
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor C00000615 0 / 0
P36888 Receptor-type tyrosine-protein kinase FLT3 Pdgfr C00000960 1 / 1
P00374 Dihydrofolate reductase Oxidoreductase C00000947 1 / 1
P03372 Estrogen receptor NR3A1 C00000615 1 / 1
P22303 Acetylcholinesterase Hydrolase C00000960 1 / 0
P35372 Mu-type opioid receptor Opioid receptor C00000947 0 / 0
Q9Y3R4 Sialidase-2 Enzyme C00000947 0 / 0
P42575 Caspase-2 C14 C00001432 0 / 0
P41145 Kappa-type opioid receptor Opioid receptor C00000947 0 / 0
P11388 DNA topoisomerase 2-alpha Isomerase C00000947 0 / 0
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily C00000615 1 / 8
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00001029 1 / 0
Q6W5P4 Neuropeptide S receptor Neuropeptide receptor C00000947 1 / 0
P52895 Aldo-keto reductase family 1 member C2 Enzyme C00000615 1 / 0
Q9GZT9 Egl nine homolog 1 Enzyme C00000615 1 / 1
Q12879 Glutamate receptor ionotropic, NMDA 2A NS C00001432 0 / 0
P22309 UDP-glucuronosyltransferase 1-1 Enzyme C00000947 5 / 1
Q05586 Glutamate receptor ionotropic, NMDA 1 NS C00001432 1 / 0
Q07869 Peroxisome proliferator-activated receptor alpha NR1C1 C00001029 0 / 0
P49327 Fatty acid synthase Transferase C00000947 0 / 0
P51452 Dual specificity protein phosphatase 3 Ser_Thr_Tyr C00000615 0 / 0
Q12794 Hyaluronidase-1 Enzyme C00000615 1 / 2
P10415 Apoptosis regulator Bcl-2 Other cytosolic protein C00000947 0 / 7
P02768 Serum albumin Secreted protein C00000947 0 / 0
P24298 Alanine aminotransferase 1 Enzyme C00000615 0 / 0
P42574 Caspase-3 C14 C00001432 0 / 0
Q8TD43 Transient receptor potential cation channel subfamily M member 4 Unclassified protein C00001432 1 / 1
P02545 Prelamin-A/C Unclassified protein C00000615 11 / 10
O75604 Ubiquitin carboxyl-terminal hydrolase 2 Enzyme C00009814 0 / 0
P28907 ADP-ribosyl cyclase 1 Enzyme C00000947 0 / 1
Q8N1Q1 Carbonic anhydrase 13 Lyase C00000947 0 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00001029 0 / 0
P14780 Matrix metalloproteinase-9 M10A C00000615 2 / 2
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 C00001029 0 / 0
P52209 6-phosphogluconate dehydrogenase, decarboxylating Enzyme C00000947 0 / 0
Q06124 Tyrosine-protein phosphatase non-receptor type 11 Tyr C00000615 4 / 2
P61073 C-X-C chemokine receptor type 4 CXC chemokine receptor C00001432 1 / 1
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) C00000615 2 / 2
P21728 D(1A) dopamine receptor Dopamine receptor C00001432 0 / 0
P09917 Arachidonate 5-lipoxygenase Oxidoreductase C00000615 0 / 0
P14618 Pyruvate kinase PKM Enzyme C00000960 0 / 0
O60218 Aldo-keto reductase family 1 member B10 Enzyme C00000615 0 / 0
Q9NZQ8 Transient receptor potential cation channel subfamily M member 5 Unclassified protein C00001432 0 / 0
P17516 Aldo-keto reductase family 1 member C4 Enzyme C00000615 1 / 0
P22310 UDP-glucuronosyltransferase 1-4 Enzyme C00000947 3 / 0
P33527 Multidrug resistance-associated protein 1 drugs C00001029 0 / 0
Q92959 Solute carrier organic anion transporter family member 2A1 Unclassified protein C00001200 1 / 0
O60669 Monocarboxylate transporter 2 Unclassified protein C00001200 0 / 0
Q05BR4 SLC16A10 protein Unclassified protein C00001200 0 / 0
P07900 Heat shock protein HSP 90-alpha Other cytosolic protein C00000615 0 / 0
P08238 Heat shock protein HSP 90-beta Other cytosolic protein C00000615 0 / 0
P42345 Serine/threonine-protein kinase mTOR Enzyme C00001431 0 / 0
Q9H0H5 Rac GTPase-activating protein 1 Unclassified protein C00000947 0 / 0
Q14191 Werner syndrome ATP-dependent helicase Enzyme C00000960 2 / 1
Q9C0B1 Alpha-ketoglutarate-dependent dioxygenase FTO Unclassified protein C00001200 1 / 2

120 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00000947 C00001431 C00009077
5594 MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk mitogen-activated protein kinase 1 (EC:2.7.11.24) C00000947 C00009077
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00000947 C00001029
153 ADRB1, ADRB1R, B1AR, BETA1AR, RHR adrenoceptor beta 1 C00001431 C00001432
596 BCL2, Bcl-2, PPP1R50 B-cell CLL/lymphoma 2 C00000947 C00001432
7153 TOP2A, TOP2, TP2A topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3) C00000947 C00009077
5595 MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK mitogen-activated protein kinase 3 (EC:2.7.11.24) C00000947 C00009077
154 ADRB2, ADRB2R, ADRBR, B2AR, BAR, BETA2AR adrenoceptor beta 2, surface C00001431 C00001432
54205 CYCS, CYC, HCS, THC4 cytochrome c, somatic C00000947 C00009077
3162 HMOX1, HMOX1D, HO-1, HSP32, bK286B10 heme oxygenase (decycling) 1 (EC:1.14.99.3) C00000947 C00000960
4780 NFE2L2, NRF2 nuclear factor, erythroid 2-like 2 C00000947 C00000960
842 CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) C00000947 C00009077
207 AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) C00000947 C00009077
581 BAX, BCL2L4 BCL2-associated X protein C00000947 C00009077
4363 ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 C00000960 C00001029
6699 SPRR1B, CORNIFIN, GADD33, SPRR1 small proline-rich protein 1B C00000947
2950 GSTP1, DFN7, FAEES3, GST3, GSTP, PI glutathione S-transferase pi 1 (EC:2.5.1.18) C00000960
2932 GSK3B glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) C00009077
4835 NQO2, DHQV, DIA6, NMOR2, QR2 NAD(P)H dehydrogenase, quinone 2 (EC:1.10.99.2) C00001029
4544 MTNR1B, FGQTL2, MEL-1B-R, MT2 melatonin receptor 1B C00001029
4240 MFGE8, BA46, EDIL1, HMFG, HsT19888, MFG-E8, MFGM, OAcGD3S, SED1, SPAG10, hP47 milk fat globule-EGF factor 8 protein C00009077
4543 MTNR1A, MEL-1A-R, MT1 melatonin receptor 1A C00001029
9429 ABCG2, ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR1, UAQTL1 ATP-binding cassette, sub-family G (WHITE), member 2 C00000947
302 ANXA2, ANX2, ANX2L4, CAL1H, LIP2, LPC2, LPC2D, P36, PAP-IV annexin A2 C00000947
393 ARHGAP4, C1, RGC1, RhoGAP4, SrGAP4, p115 Rho GTPase activating protein 4 C00000947
468 ATF4, CREB-2, CREB2, TAXREB67, TXREB activating transcription factor 4 C00000947
472 ATM, AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1 ataxia telangiectasia mutated (EC:2.7.11.1) C00000947
2683 B4GALT1, B4GAL-T1, CDG2D, GGTB2, GT1, GTB, beta4Gal-T1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (EC:2.4.1.22 2.4.1.90 2.4.1.38) C00000947
56751 BARHL1 BarH-like homeobox 1 C00000947
1545 CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) C00001029
637 BID, FP497 BH3 interacting domain death agonist C00000947
388962 BOLA3, MMDS2 bolA family member 3 C00000947
79184 BRCC3, BRCC36, C6.1A, CXorf53 BRCA1/BRCA2-containing complex, subunit 3 (EC:3.1.2.15) C00000947
694 BTG1 B-cell translocation gene 1, anti-proliferative C00000947
840 CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) C00000947
841 CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) C00000947
6347 CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF chemokine (C-C motif) ligand 2 C00000947
595 CCND1, BCL1, D11S287E, PRAD1, U21B31 cyclin D1 C00000947
930 CD19, B4, CVID3 CD19 molecule C00000947
975 CD81, CVID6, S5.7, TAPA1, TSPAN28 CD81 molecule C00000947
928 CD9, BTCC-1, DRAP-27, MIC3, MRP-1, TSPAN-29, TSPAN29 CD9 molecule C00000947
1054 CEBPG, GPE1BP, IG/EBP-1 CCAAT/enhancer binding protein (C/EBP), gamma C00000947
10978 CLP1, HEAB, hClp1 cleavage and polyadenylation factor I subunit 1 (EC:2.7.1.78) C00000947
10063 COX17 COX17 cytochrome c oxidase copper chaperone C00000947
3627 CXCL10, C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1 chemokine (C-X-C motif) ligand 10 C00000947
7913 DEK, D6S231E DEK oncogene C00000947
1786 DNMT1, ADCADN, AIM, CXXC9, DNMT, HSN1E, MCMT DNA (cytosine-5-)-methyltransferase 1 (EC:2.1.1.37) C00000947
2130 EWSR1, EWS, bK984G1.4 EWS RNA-binding protein 1 C00000947
355 FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6 Fas cell surface death receptor C00000947
2323 FLT3LG, FL, FLT3L fms-related tyrosine kinase 3 ligand C00000947
2495 FTH1, FHC, FTH, FTHL6, PIG15, PLIF ferritin, heavy polypeptide 1 (EC:1.16.3.1) C00000947
2896 GRN, CLN11, GEP, GP88, PCDGF, PEPI, PGRN granulin C00000947
3014 H2AFX, H2A.X, H2A/X, H2AX H2A histone family, member X C00000947
3054 HCFC1, CFF, HCF-1, HCF1, HFC1, MRX3, VCAF host cell factor C1 (VP16-accessory protein) C00000947
3232 HOXD3, HOX1D, HOX4, HOX4A, Hox-4.1 homeobox D3 C00000947
3329 HSPD1, CPN60, GROEL, HLD4, HSP-60, HSP60, HSP65, HuCHA60, SPG13 heat shock 60kDa protein 1 (chaperonin) C00000947
3383 ICAM1, BB2, CD54, P3.58 intercellular adhesion molecule 1 C00000947
3586 IL10, CSIF, GVHDS, IL-10, IL10A, TGIF interleukin 10 C00000947
3553 IL1B, IL-1, IL1-BETA, IL1F2 interleukin 1, beta C00000947
3559 IL2RA, CD25, IDDM10, IL2R, TCGFR interleukin 2 receptor, alpha C00000947
9235 IL32, IL-32alpha, IL-32beta, IL-32delta, IL-32gamma, NK4, TAIF, TAIFa, TAIFb, TAIFc, TAIFd interleukin 32 C00000947
3662 IRF4, LSIRF, MUM1, NF-EM5 interferon regulatory factor 4 C00000947
3683 ITGAL, CD11A, LFA-1, LFA1A integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) C00000947
3689 ITGB2, CD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) C00000947
4067 LYN, JTK8, p53Lyn, p56Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog (EC:2.7.10.2) C00000947
5604 MAP2K1, CFC3, MAPKK1, MEK1, MKK1, PRKMK1 mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) C00000947
5605 MAP2K2, CFC4, MAPKK2, MEK2, MKK2, PRKMK2 mitogen-activated protein kinase kinase 2 (EC:2.7.12.2) C00000947
4282 MIF, GIF, GLIF, MMIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) (EC:5.3.3.12 5.3.2.1) C00000947
64975 MRPL41, BMRP, MRP-L27, MRPL27, RPML27 mitochondrial ribosomal protein L41 C00000947
4493 MT1E, MT1, MTD metallothionein 1E C00000947
653361 NCF1, NCF1A, NOXO2, SH3PXD1A, p47phox neutrophil cytosolic factor 1 C00000947
4792 NFKBIA, IKBA, MAD-3, NFKBI nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha C00000947
4851 NOTCH1, TAN1, hN1 notch 1 C00000947
4869 NPM1, B23, NPM nucleophosmin (nucleolar phosphoprotein B23, numatrin) C00000947
5175 PECAM1, CD31, CD31/EndoCAM, GPIIA', PECA1, PECAM-1, endoCAM platelet/endothelial cell adhesion molecule 1 C00000947
5187 PER1, PER, RIGUI, hPER period circadian clock 1 C00000947
5327 PLAT, T-PA, TPA plasminogen activator, tissue (EC:3.4.21.68) C00000947
5328 PLAU, ATF, BDPLT5, QPD, UPA, URK, u-PA plasminogen activator, urokinase (EC:3.4.21.73) C00000947
7916 PRRC2A, BAT2, D6S51, D6S51E, G2 proline-rich coiled-coil 2A C00000947
5743 PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) C00000947
5747 PTK2, FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK protein tyrosine kinase 2 (EC:2.7.10.2) C00000947
5879 RAC1, Rac-1, TC-25, p21-Rac1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) C00000947
5915 RARB, HAP, NR1B2, RRB2 retinoic acid receptor, beta C00000947
5970 RELA, NFKB3, p65 v-rel avian reticuloendotheliosis viral oncogene homolog A C00000947
6128 RPL6, L6, SHUJUN-2, TAXREB107, TXREB1 ribosomal protein L6 C00000947
6285 S100B, NEF, S100, S100-B, S100beta S100 calcium binding protein B C00000947
6286 S100P, MIG9 S100 calcium binding protein P C00000947
5054 SERPINE1, PAI, PAI-1, PAI1, PLANH1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 C00000947
7536 SF1, BBP, D11S636, MBBP, ZCCHC25, ZFM1, ZNF162 splicing factor 1 C00000947
6574 SLC20A1, GLVR1, Glvr-1, PIT1, PiT-1 solute carrier family 20 (phosphate transporter), member 1 C00000947
29110 TBK1, NAK, T2K TANK-binding kinase 1 (EC:2.7.11.1) C00000960
6772 STAT1, CANDF7, ISGF-3, STAT91 signal transducer and activator of transcription 1, 91kDa C00000947
6777 STAT5B, STAT5 signal transducer and activator of transcription 5B C00000947
6778 STAT6, D12S1644, IL-4-STAT, STAT6B, STAT6C signal transducer and activator of transcription 6, interleukin-4 induced C00000947
6817 SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) C00000947
6932 TCF7, TCF-1 transcription factor 7 (T-cell specific, HMG-box) C00000947
7083 TK1, TK2 thymidine kinase 1, soluble (EC:2.7.1.21) C00000947
7124 TNF, DIF, TNF-alpha, TNFA, TNFSF2 tumor necrosis factor C00000947
943 TNFRSF8, CD30, D1S166E, Ki-1 tumor necrosis factor receptor superfamily, member 8 C00000947
7150 TOP1, TOPI topoisomerase (DNA) I (EC:5.99.1.2) C00000947
2829 XCR1, CCXCR1, GPR5 chemokine (C motif) receptor 1 C00000947
51042 ZNF593, ZT86 zinc finger protein 593 C00000947
1544 CYP1A2, CP12, P3-450, P450(PA) cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) C00001029
196 AHR, bHLHe76 aryl hydrocarbon receptor C00001029
486 FXYD2, ATP1G1, HOMG2 FXYD domain containing ion transport regulator 2 C00001431
331 XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3 X-linked inhibitor of apoptosis C00001431
846 CASR, CAR, EIG8, FHH, FIH, GPRC2A, HHC, HHC1, HYPOC1, NSHPT, PCAR1 calcium-sensing receptor C00001432
56616 DIABLO, DFNA64, SMAC diablo, IAP-binding mitochondrial protein C00001432
5599 MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c mitogen-activated protein kinase 8 (EC:2.7.11.24) C00001432
4843 NOS2, HEP-NOS, INOS, NOS, NOS2A nitric oxide synthase 2, inducible (EC:1.14.13.39) C00001432
31 ACACA, ACAC, ACACAD, ACC, ACC1, ACCA acetyl-CoA carboxylase alpha (EC:6.4.1.2 6.3.4.14) C00001200
1487 CTBP1, BARS C-terminal binding protein 1 C00001200
1488 CTBP2 C-terminal binding protein 2 C00001200
1586 CYP17A1, CPT7, CYP17, P450C17, S17AH cytochrome P450, family 17, subfamily A, polypeptide 1 (EC:1.14.99.9 4.1.2.30) C00001200
14103 C00001200
2516 NR5A1, AD4BP, ELP, FTZ1, FTZF1, POF7, SF-1, SF1, SPGF8, SRXY3 nuclear receptor subfamily 5, group A, member 1 C00001200
10891 PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1 peroxisome proliferator-activated receptor gamma, coactivator 1 alpha C00001200
23411 SIRT1, SIR2L1 sirtuin 1 C00001200
6566 SLC16A1, HHF7, MCT, MCT1 solute carrier family 16 (monocarboxylate transporter), member 1 C00001200
6647 SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer superoxide dismutase 1, soluble (EC:1.15.1.1) C00001200

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (123)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#614279 46,xy sex reversal 8; srxy8 P17516
P52895
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#600807 Asthma, susceptibility to Q13093
#608584 Asthma-related traits, susceptibility to, 2 Q6W5P4
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#601816 Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 P22309
#210900 Bloom syndrome; blm P54132
%606641 Body mass index; bmi P37231
#114480 Breast cancer P38398
#604370 Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 P38398
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#609338 Carotid intimal medial thickness 1 P37231
#118300 Charcot-marie-tooth disease and deafness Q01453
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#118220 Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a Q01453
#114500 Colorectal cancer; crc P18054
P84022
Q14191
#218800 Crigler-najjar syndrome, type i P22309
P22310
#606785 Crigler-najjar syndrome, type ii P22309
P22310
#119900 Digital clubbing, isolated congenital P15428
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#237500 Dubin-johnson syndrome; djs Q92887
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#609820 Erythrocytosis, familial, 3; ecyt3 Q9GZT9
#133239 Esophageal cancer P04637
P18054
#615363 Estrogen resistance; estrr P03372
#301500 Fabry disease P06280
#600274 Frontotemporal dementia; ftd P10636
#143500 Gilbert syndrome P22309
P22310
#137750 Glaucoma 1, open angle, a; glc1a Q16678
#231300 Glaucoma 3, primary congenital, a; glc3a Q16678
#137760 Glaucoma, primary open angle; poag Q16678
#137800 Glioma susceptibility 1; glm1 P37231
#232300 Glycogen storage disease ii P10253
#612938 Growth retardation, developmental delay, coarse facies, and early death; gdfd Q9C0B1
#139393 Guillain-barre syndrome, familial; gbs Q01453
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#114550 Hepatocellular carcinoma P08581
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#237900 Hyperbilirubinemia, transient familial neonatal; hblrtfn P22309
#143860 Hyperchlorhidrosis, isolated O43570
#145000 Hyperparathyroidism 1; hrpt1 O00255
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#145900 Hypertrophic neuropathy of dejerine-sottas Q01453
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#614441 Hypertrophic osteoarthropathy, primary, autosomal recessive, 2; phoar2 Q92959
#146300 Hypophosphatasia, adult P05186
#241510 Hypophosphatasia, childhood P05186
#241500 Hypophosphatasia, infantile P05186
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#147050 Ige responsiveness, atopic; iger Q13093
#603932 Intervertebral disc disease; idd P14780
#607785 Juvenile myelomonocytic leukemia; jmml Q06124
#151100 Leopard syndrome 1 Q06124
#601626 Leukemia, acute myeloid; aml P36888
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#613688 Long qt syndrome 2; lqt2 Q12809
#211980 Lung cancer P00533
P04637
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613839 Megaloblastic anemia due to dihydrofolate reductase deficiency P00374
#614254 Mental retardation, autosomal dominant 8; mrd8 Q05586
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#156250 Metachondromatosis; metcds Q06124
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#601492 Mucopolysaccharidosis, type ix; mps9 Q12794
#259600 Multicentric osteolysis, nodulosis, and arthropathy; mona P08253
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#162500 Neuropathy, hereditary, with liability to pressure palsies; hnpp Q01453
#163950 Noonan syndrome 1; ns1 Q06124
#601665 Obesity P37231
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#167000 Ovarian cancer P38398
#614320 Pancreatic cancer, susceptibility to, 4; pnca4 P38398
#260500 Papilloma of choroid plexus; cpp P04637
#260540 Parkinson-dementia syndrome P10636
#604229 Peters anomaly Q16678
#172700 Pick disease of brain P10636
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#614278 Platelet-activating factor acetylhydrolase deficiency; pafad Q13093
#614390 Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 P00734
#604559 Progressive familial heart block, type ib; pfhb1b Q8TD43
#613679 Prothrombin deficiency, congenital P00734
#605074 Renal cell carcinoma, papillary, 1; rccp1 P08581
#275210 Restrictive dermopathy, lethal P02545
#600852 Retinitis pigmentosa 17; rp17 P22748
#180300 Rheumatoid arthritis; ra Q9H015
#609620 Short qt syndrome 1; sqt1 Q12809
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#605361 Spinocerebellar ataxia 14; sca14 P05129
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
#601367 Stroke, ischemic P00734
P24723
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#187950 Thrombocythemia 1; thcyt1 P40225
#188050 Thrombophilia due to thrombin defect; thph1 P00734
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#277700 Werner syndrome; wrn Q14191
#193670 Whim syndrome P61073
#278300 Xanthinuria, type i P47989
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253
#112100 Yt blood group antigen P22303

KEGG DISEASE (113)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
P04637 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
P04637 (marker)
P08581 (related)
Q16790 (marker)
H01197 Dihydrofolate reductase (DHFR) deficiency P00374 (related)
H00016 Oral cancer P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
H00017 Esophageal cancer P00533 (related)
P04637 (related)
P04637 (marker)
P35354 (related)
H00018 Gastric cancer P00533 (related)
P04637 (related)
P08581 (related)
P10415 (related)
H00022 Bladder cancer P00533 (related)
P04637 (related)
H00028 Choriocarcinoma P00533 (related)
P03956 (related)
P04637 (related)
P08253 (related)
P10415 (related)
H00030 Cervical cancer P00533 (related)
P10415 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
H00223 Inherited thrombophilia P00734 (related)
H01254 Congenital prothrombin deficiency P00734 (related)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
Q01453 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
P37231 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00026 Endometrial Cancer P03372 (marker)
P04637 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
Q01196 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
P10415 (related)
P28907 (marker)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
P10415 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00019 Pancreatic cancer P04637 (related)
P04637 (marker)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00025 Penile cancer P04637 (related)
P04637 (marker)
P08253 (related)
P14780 (related)
P35354 (related)
H00027 Ovarian cancer P04637 (related)
P38398 (related)
H00029 Vulvar cancer P04637 (related)
H00031 Breast cancer P04637 (related)
P38398 (related)
H00032 Thyroid cancer P04637 (related)
P37231 (related)
H00036 Osteosarcoma P04637 (related)
P08684 (marker)
H00038 Malignant melanoma P04637 (related)
P14679 (marker)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
P10415 (related)
H00044 Cancer of the anal canal P04637 (related)
H00046 Cholangiocarcinoma P04637 (related)
P08581 (related)
P35354 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00063 Spinocerebellar ataxia (SCA) P05129 (related)
Q9NUW8 (related)
H00213 Hypophosphatasia P05186 (related)
H00125 Fabry disease P06280 (related)
H00472 Torg-Winchester syndrome P08253 (related)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00054 Nasopharyngeal cancer P10415 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00023 Testicular cancer P10696 (marker)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H01205 Coumarin resistance P11712 (related)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00479 Metaphyseal dysplasias P14780 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00208 Hyperbilirubinemia P22309 (related)
Q92887 (related)
H00527 Retinitis pigmentosa (RP) P22748 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00003 Acute myeloid leukemia (AML) P36888 (related)
Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00409 Type II diabetes mellitus P37231 (related)
Q9C0B1 (related)
H00227 Congenital amegakaryocytic thrombocytopenia (CAMT) P40225 (marker)
H00192 Xanthinuria P47989 (related)
H00094 DNA repair defects P54132 (related)
H00296 Defects in RecQ helicases P54132 (related)
Q14191 (related)
H00097 Chemokine receptor defect P61073 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
Q03164 (related)
Q03164 (marker)
H00978 Thrombocytopenia (THC) Q01196 (related)
H01296 Hereditary neuropathy with liability to pressure palsies (HNPP) Q01453 (related)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00408 Type I diabetes mellitus Q04759 (related)
H00523 Noonan syndrome and related disorders Q06124 (related)
H01018 Metachondromatosis Q06124 (related)
H00133 Mucopolysaccharidosis type IX (MPS9) Q12794 (related)
H00421 Mucopolysaccharidosis (MPS) Q12794 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
H00612 Primary open angle glaucoma Q16678 (related)
H01075 Peters anomaly Q16678 (related)
H01159 Anterior segment dysgenesis (ASD) Q16678 (related)
H01203 Primary congenital glaucoma (PCG) Q16678 (related)
H01263 Progressive cardiac conduction defect (PCCD) Q8TD43 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)
H00926 Growth retardation, developmental delay, coarse facies, and early death Q9C0B1 (related)
H00236 Congenital polycythemia Q9GZT9 (related)
H00286 Crohn's disease Q9H015 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

29 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D056486 Drug-Induced Liver Injury C00000947
C00001431
D009336 Necrosis C00001432
C00001200
D012640 Seizures C00001431
C00001432
D006948 Hyperkinesis C00001431
C00001432
D006331 Heart Diseases C00000947
C00001432
D006332 Cardiomegaly C00001431
D034381 Hearing Loss C00000947
D003556 Cystitis C00000947
D020138 HYPERHOMOCYSTEINEMIA C00000947
D008107 Liver Diseases C00000947
D017114 Liver Failure, Acute C00000947
D008113 Liver Neoplasms C00000947
D008325 Mammary Neoplasms, Experimental C00000947
D009362 Neoplasm Metastasis C00000947
D007669 Kidney Calculi C00001186
D002471 Cell Transformation, Neoplastic C00000947
D011041 Poisoning C00001431
D001943 Breast Neoplasms C00000947
D000740 Anemia C00001432
D001930 Brain Injuries C00001432
D002545 Brain Ischemia C00001432
D007859 Learning Disorders C00001432
D008569 Memory Disorders C00001432
D050197 Atherosclerosis C00000947
D009410 Nerve Degeneration C00001432
D014202 Tremor C00001432
D006943 Hyperglycemia C00001200
D028361 Mitochondrial Diseases C00001200
D009135 Muscular Diseases C00001200