KEGG   PATHWAY: hsa05132
Entry
hsa05132                    Pathway                                
Name
Salmonella infection - Homo sapiens (human)
Description
Salmonella infection usually presents as a self-limiting gastroenteritis or the more severe typhoid fever and bacteremia. The common disease-causing Salmonella species in human is a single species, Salmonella enterica, which has numerous serovars.
Following intestinal colonization Salmonella inject effector proteins into the host cells using a type III secretion system (T3SS), T3SS1. Then a small group of effector proteins induce rearrangement of the actin cytoskeleton resulting in membrane ruffles and rapid internalization of the bacteria.The T3SS2 is responsible for translocating effector proteins that direct Salmonella-containing vacuole (SCV) maturation. The majority of the bacteria are known to survive and replicate in SCV.
Class
Human Diseases; Infectious disease: bacterial
Pathway map
hsa05132  Salmonella infection
hsa05132

Network
nt06181  Salmonella
nt06505  WNT signaling
nt06516  TNF signaling
nt06521  NLR signaling
  Element
N01112  Salmonella SopE/E2 to NOD-NFKB signaling pathway
N01113  Salmonella SseK1 to TNF-NFKB signaling pathway
N01114  Salmonella SseK3 to TNF-NFKB signaling pathway
N01116  Salmonella SseL to TNF-NFKB signaling pathway
N01117  Salmonella GogB to TNF-NFKB signaling pathway
N01118  Salmonella SpvD to TNF-NFKB signaling pathway
N01120  Salmonella SptP to RAC/CDC42-PAK-ERK signaling pathway
N01121  Salmonella SpvC to ERK signaling pathway
N01122  Salmonella PipA/GogA/GtgA to TNF-NFKB signaling pathway
N01123  Salmonella AvrA to TNF-NFKB signaling pathway
N01124  Salmonella AvrA to beta-catenin signaling pathway
N01125  Salmonella AvrA to TNF-JNK signaling pathway
N01126  Salmonella SipB to Inflammasome signaling pathway
N01127  Salmonella SopE to Inflammasome signaling pathway
N01128  Salmonella SopE to RAC signaling pathway
N01129  Salmonella SopB to ARNO-ARF-ACTB/G signaling pathway
N01130  Salmonella SopB to RhoA signaling pathway
N01131  Salmonella SopE/E2 to RhoA signaling pathway
N01132  Salmonella SopE/E2 to RhoG signaling pathway
N01133  Salmonella SopB to RhoG signaling pathway
N01134  Salmonella SopB to CDC42 signaling pathway
N01296  Salmonella SopD2 to Rab7-regulated microtubule minus-end directed transport
N01298  Salmonella SifA to microtubule plus-end directed transport
N01299  Salmonella PipB2 to microtubule plus-end directed transport
N01301  Salmonella SifA to Tethering of late endosomes and lysosomes
N01303  Salmonella SopB to Early endosomal fusion
N01305  Salmonella SopB to ANXA2-S100A10-regulated actin cytoskeleton
Disease
H00111  Typhoid fever
Organism
Homo sapiens (human) [GN:hsa]
Gene
10000  AKT3; RAC-gamma serine/threonine-protein kinase isoform 1 [KO:K04456] [EC:2.7.11.1]
10006  ABI1; abl interactor 1 isoform a [KO:K23649]
10092  ARPC5; actin-related protein 2/3 complex subunit 5 isoform 1 [KO:K05754]
10093  ARPC4; actin-related protein 2/3 complex subunit 4 isoform a [KO:K05755]
10094  ARPC3; actin-related protein 2/3 complex subunit 3 isoform 1 [KO:K05756]
10095  ARPC1B; actin-related protein 2/3 complex subunit 1B [KO:K05757]
10096  ACTR3; actin-related protein 3 isoform 1 [KO:K18584]
10097  ACTR2; actin-related protein 2 isoform b [KO:K17260]
10109  ARPC2; actin-related protein 2/3 complex subunit 2 [KO:K05758]
10120  ACTR1B; beta-centractin [KO:K16575]
10121  ACTR1A; alpha-centractin [KO:K16575]
10333  TLR6; toll-like receptor 6 precursor [KO:K10169]
10376  TUBA1B; tubulin alpha-1B chain [KO:K07374]
10381  TUBB3; tubulin beta-3 chain isoform 1 [KO:K07375]
10382  TUBB4A; tubulin beta-4A chain isoform 3 [KO:K07375]
10383  TUBB4B; tubulin beta-4B chain [KO:K07375]
103910  MYL12B; myosin regulatory light chain 12B [KO:K12757]
10392  NOD1; nucleotide-binding oligomerization domain-containing protein 1 isoform 1 [KO:K08727]
10398  MYL9; myosin regulatory light polypeptide 9 isoform a [KO:K12755]
10454  TAB1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform alpha [KO:K04403]
10540  DCTN2; dynactin subunit 2 isoform 3 [KO:K10424]
10552  ARPC1A; actin-related protein 2/3 complex subunit 1A isoform 1 [KO:K05757]
10627  MYL12A; myosin regulatory light chain 12A isoform 1 [KO:K12757]
10640  EXOC5; exocyst complex component 5 [KO:K19984]
10671  DCTN6; dynactin subunit 6 [KO:K10428]
10787  NCKAP1; nck-associated protein 1 isoform 1 [KO:K05750]
10810  WASF3; actin-binding protein WASF3 isoform 1 [KO:K06083]
11035  RIPK3; receptor-interacting serine/threonine-protein kinase 3 [KO:K08847] [EC:2.7.11.1]
112574  SNX18; sorting nexin-18 isoform b [KO:K17923]
11258  DCTN3; dynactin subunit 3 isoform 1 [KO:K10425]
112714  TUBA3E; tubulin alpha-3E chain [KO:K07374]
113146  AHNAK2; protein AHNAK2 isoform 1 [KO:K23934]
113457  TUBA3D; tubulin alpha-3D chain [KO:K07374]
114548  NLRP3; NACHT, LRR and PYD domains-containing protein 3 isoform a [KO:K12800]
114609  TIRAP; toll/interleukin-1 receptor domain-containing adapter protein isoform a [KO:K05403]
1147  CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform 1 [KO:K04467] [EC:2.7.11.10]
127829  ARL8A; ADP-ribosylation factor-like protein 8A isoform 1 [KO:K07955]
140735  DYNLL2; dynein light chain 2, cytoplasmic [KO:K10418]
1432  MAPK14; mitogen-activated protein kinase 14 isoform 2 [KO:K04441] [EC:2.7.11.24]
1434  CSE1L; exportin-2 isoform 1 [KO:K18423]
147700  KLC3; kinesin light chain 3 [KO:K10407]
1499  CTNNB1; catenin beta-1 isoform 1 [KO:K02105]
1639  DCTN1; dynactin subunit 1 isoform 1 [KO:K04648]
1778  DYNC1H1; cytoplasmic dynein 1 heavy chain 1 [KO:K10413]
1780  DYNC1I1; cytoplasmic dynein 1 intermediate chain 1 isoform a [KO:K10415]
1781  DYNC1I2; cytoplasmic dynein 1 intermediate chain 2 isoform 1 [KO:K10415]
1783  DYNC1LI2; cytoplasmic dynein 1 light intermediate chain 2 isoform 1 [KO:K10416]
1785  DNM2; dynamin-2 isoform 1 [KO:K23484]
197259  MLKL; mixed lineage kinase domain-like protein isoform 1 [KO:K08849] [EC:2.7.11.1]
203068  TUBB; tubulin beta chain isoform b [KO:K07375]
207  AKT1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
208  AKT2; RAC-beta serine/threonine-protein kinase isoform 1 [KO:K04456] [EC:2.7.11.1]
23118  TAB2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform a [KO:K04404]
2316  FLNA; filamin-A isoform 2 [KO:K04437]
23191  CYFIP1; cytoplasmic FMR1-interacting protein 1 isoform a [KO:K05749]
23207  PLEKHM2; pleckstrin homology domain-containing family M member 2 isoform 1 [KO:K15348]
23265  EXOC7; exocyst complex component 7 isoform 4 [KO:K07195]
23339  VPS39; vam6/Vps39-like protein isoform a [KO:K20183]
2353  FOS; protein c-Fos [KO:K04379]
23643  LY96; lymphocyte antigen 96 isoform 1 precursor [KO:K05400]
257364  SNX33; sorting nexin-33 isoform 1 [KO:K17923]
257397  TAB3; TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform 1 [KO:K12793]
25828  TXN2; thioredoxin, mitochondrial precursor [KO:K03671]
2597  GAPDH; glyceraldehyde-3-phosphate dehydrogenase isoform 1 [KO:K00134] [EC:1.2.1.12]
260334  TUBB8B; tubulin beta 8B isoform 1 [KO:K07375]
26084  ARHGEF26; rho guanine nucleotide exchange factor 26 isoform 1 [KO:K13744]
26263  FBXO22; F-box only protein 22 isoform a [KO:K10302]
26999  CYFIP2; cytoplasmic FMR1-interacting protein 2 isoform c [KO:K05749]
27072  VPS41; vacuolar protein sorting-associated protein 41 homolog isoform 1 [KO:K20184]
27128  CYTH4; cytohesin-4 isoform 1 [KO:K18441]
29108  PYCARD; apoptosis-associated speck-like protein containing a CARD isoform a [KO:K12799]
29109  FHOD1; FH1/FH2 domain-containing protein 1 isoform 2 [KO:K23938]
29895  MYL11; myosin regulatory light chain 11 [KO:K12758]
302  ANXA2; annexin A2 isoform 2 [KO:K17092]
3071  NCKAP1L; nck-associated protein 1-like isoform 1 [KO:K05750]
3265  HRAS; GTPase HRas isoform 1 [KO:K02833]
329  BIRC2; baculoviral IAP repeat-containing protein 2 isoform 1 [KO:K16060]
330  BIRC3; baculoviral IAP repeat-containing protein 3 [KO:K16060]
3320  HSP90AA1; heat shock protein HSP 90-alpha isoform 2 [KO:K04079]
3326  HSP90AB1; heat shock protein HSP 90-beta isoform a [KO:K04079]
338382  RAB7B; ras-related protein Rab-7b isoform a [KO:K07898]
345456  PFN3; profilin-3 [KO:K05759]
347688  TUBB8; tubulin beta-8 chain isoform 1 [KO:K07375]
347733  TUBB2B; tubulin beta-2B chain [KO:K07375]
3551  IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform 1 [KO:K07209] [EC:2.7.11.10]
3553  IL1B; interleukin-1 beta proprotein [KO:K04519]
3569  IL6; interleukin-6 isoform 1 precursor [KO:K05405]
3576  CXCL8; interleukin-8 isoform 1 precursor [KO:K10030]
3606  IL18; interleukin-18 isoform 1 precursor [KO:K05482]
3654  IRAK1; interleukin-1 receptor-associated kinase 1 isoform 1 [KO:K04730] [EC:2.7.11.1]
3725  JUN; transcription factor Jun [KO:K04448]
375  ARF1; ADP-ribosylation factor 1 [KO:K07937]
375189  PFN4; profilin-4 [KO:K05759]
3798  KIF5A; kinesin heavy chain isoform 5A isoform 1 [KO:K10396] [EC:5.6.1.3]
3799  KIF5B; kinesin-1 heavy chain [KO:K10396] [EC:5.6.1.3]
3800  KIF5C; kinesin heavy chain isoform 5C [KO:K10396] [EC:5.6.1.3]
382  ARF6; ADP-ribosylation factor 6 [KO:K07941]
3831  KLC1; kinesin light chain 1 isoform 2 [KO:K10407]
3836  KPNA1; importin subunit alpha-5 [KO:K23940]
3839  KPNA3; importin subunit alpha-4 [KO:K23583]
3840  KPNA4; importin subunit alpha-3 [KO:K23583]
387  RHOA; transforming protein RhoA isoform 1 precursor [KO:K04513]
388  RHOB; rho-related GTP-binding protein RhoB [KO:K07856]
391  RHOG; rho-related GTP-binding protein RhoG [KO:K07863]
399  RHOH; rho-related GTP-binding protein RhoH precursor [KO:K07873]
4074  M6PR; cation-dependent mannose-6-phosphate receptor isoform 1 precursor [KO:K10089]
4609  MYC; myc proto-oncogene protein isoform 1 [KO:K04377]
4615  MYD88; myeloid differentiation primary response protein MyD88 isoform 2 [KO:K04729]
4633  MYL2; myosin regulatory light chain 2, ventricular/cardiac muscle isoform isoform 1 [KO:K10351]
4636  MYL5; myosin light chain 5 isoform 1 [KO:K12753]
4646  MYO6; unconventional myosin-VI isoform 2 [KO:K10358]
4671  NAIP; baculoviral IAP repeat-containing protein 1 isoform 1 [KO:K12807]
4790  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform 2 proprotein [KO:K02580]
4792  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
5058  PAK1; serine/threonine-protein kinase PAK 1 isoform 2 [KO:K04409] [EC:2.7.11.1]
5063  PAK3; serine/threonine-protein kinase PAK 3 isoform d [KO:K05733] [EC:2.7.11.1]
51135  IRAK4; interleukin-1 receptor-associated kinase 4 isoform a [KO:K04733] [EC:2.7.11.1]
51143  DYNC1LI1; cytoplasmic dynein 1 light intermediate chain 1 isoform 1 [KO:K10416]
51164  DCTN4; dynactin subunit 4 isoform b [KO:K10426]
51176  LEF1; lymphoid enhancer-binding factor 1 isoform 1 [KO:K04492]
51209  RAB9B; ras-related protein Rab-9B [KO:K07900]
51429  SNX9; sorting nexin-9 [KO:K17923]
51626  DYNC2LI1; cytoplasmic dynein 2 light intermediate chain 1 isoform 1 [KO:K10417]
51807  TUBA8; tubulin alpha-8 chain isoform 1 [KO:K07374]
5216  PFN1; profilin-1 isoform 2 [KO:K05759]
5217  PFN2; profilin-2 isoform b [KO:K05759]
5286  PIK3C2A; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha isoform 1 [KO:K00923] [EC:2.7.1.154]
5287  PIK3C2B; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform 1 [KO:K00923] [EC:2.7.1.154]
5288  PIK3C2G; phosphatidylinositol 3-kinase C2 domain-containing subunit gamma isoform 1 [KO:K00923] [EC:2.7.1.154]
5289  PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3 isoform 1 [KO:K00914] [EC:2.7.1.137]
5290  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
5291  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform 1 [KO:K00922] [EC:2.7.1.153]
5293  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform 1 [KO:K00922] [EC:2.7.1.153]
5294  PIK3CG; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform [KO:K21289] [EC:2.7.1.153]
54106  TLR9; toll-like receptor 9 precursor [KO:K10161]
5420  PODXL; podocalyxin isoform 1 precursor [KO:K06817]
54205  CYCS; cytochrome c [KO:K08738]
55207  ARL8B; ADP-ribosylation factor-like protein 8B [KO:K07955]
55770  EXOC2; exocyst complex component 2 [KO:K17637]
55823  VPS11; vacuolar protein sorting-associated protein 11 homolog isoform 1 [KO:K20179]
55845  BRK1; protein BRICK1 [KO:K05752]
5585  PKN1; serine/threonine-protein kinase N1 isoform 2 [KO:K06071] [EC:2.7.11.13]
55860  ACTR10; actin-related protein 10 [KO:K16576]
5594  MAPK1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
5595  MAPK3; mitogen-activated protein kinase 3 isoform 1 [KO:K04371] [EC:2.7.11.24]
5599  MAPK8; mitogen-activated protein kinase 8 isoform alpha2 [KO:K04440] [EC:2.7.11.24]
5600  MAPK11; mitogen-activated protein kinase 11 [KO:K04441] [EC:2.7.11.24]
5601  MAPK9; mitogen-activated protein kinase 9 isoform alpha2 [KO:K04440] [EC:2.7.11.24]
5602  MAPK10; mitogen-activated protein kinase 10 isoform 1 [KO:K04440] [EC:2.7.11.24]
5603  MAPK13; mitogen-activated protein kinase 13 [KO:K04441] [EC:2.7.11.24]
5604  MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform 1 [KO:K04368] [EC:2.7.12.2]
5605  MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 isoform 1 [KO:K04369] [EC:2.7.12.2]
5606  MAP2K3; dual specificity mitogen-activated protein kinase kinase 3 isoform B [KO:K04432] [EC:2.7.12.2]
5608  MAP2K6; dual specificity mitogen-activated protein kinase kinase 6 isoform 1 [KO:K04433] [EC:2.7.12.2]
5609  MAP2K7; dual specificity mitogen-activated protein kinase kinase 7 isoform 3 [KO:K04431] [EC:2.7.12.2]
57180  ACTR3B; actin-related protein 3B isoform 1 [KO:K18584]
57381  RHOJ; rho-related GTP-binding protein RhoJ [KO:K07864]
57617  VPS18; vacuolar protein sorting-associated protein 18 homolog [KO:K20181]
578  BAK1; bcl-2 homologous antagonist/killer [KO:K14021]
5788  PTPRC; receptor-type tyrosine-protein phosphatase C isoform 1 precursor [KO:K06478] [EC:3.1.3.48]
581  BAX; apoptosis regulator BAX isoform alpha [KO:K02159]
58484  NLRC4; NLR family CARD domain-containing protein 4 isoform a [KO:K12805]
58498  MYL7; myosin regulatory light chain 2, atrial isoform [KO:K12754]
5868  RAB5A; ras-related protein Rab-5A isoform 1 [KO:K07887]
5869  RAB5B; ras-related protein Rab-5B isoform 1 [KO:K07888]
5878  RAB5C; ras-related protein Rab-5C isoform a [KO:K07889]
5879  RAC1; ras-related C3 botulinum toxin substrate 1 isoform Rac1 [KO:K04392]
5894  RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform b [KO:K04366] [EC:2.7.11.1]
5898  RALA; ras-related protein Ral-A precursor [KO:K07834]
596  BCL2; apoptosis regulator Bcl-2 isoform alpha [KO:K02161]
5970  RELA; transcription factor p65 isoform 1 [KO:K04735]
60  ACTB; actin, cytoplasmic 1 [KO:K05692]
60412  EXOC4; exocyst complex component 4 isoform a [KO:K06111]
6188  RPS3; small ribosomal subunit protein uS3 isoform 1 [KO:K02985]
6237  RRAS; ras-related protein R-Ras [KO:K07829]
6281  S100A10; protein S100-A10 [KO:K17274]
6300  MAPK12; mitogen-activated protein kinase 12 isoform 1 [KO:K04441] [EC:2.7.11.24]
63916  ELMO2; engulfment and cell motility protein 2 isoform a [KO:K18985]
6416  MAP2K4; dual specificity mitogen-activated protein kinase kinase 4 isoform 1 [KO:K04430] [EC:2.7.12.2]
64601  VPS16; vacuolar protein sorting-associated protein 16 homolog isoform 1 [KO:K20180]
64746  ACBD3; Golgi resident protein GCP60 [KO:K23935]
64837  KLC2; kinesin light chain 2 isoform 1 [KO:K10407]
6500  SKP1; S-phase kinase-associated protein 1 isoform b [KO:K03094]
65082  VPS33A; vacuolar protein sorting-associated protein 33A isoform 1 [KO:K20182]
653857  ACTR3C; actin-related protein 3C isoform a precursor [KO:K18584]
6885  MAP3K7; mitogen-activated protein kinase kinase kinase 7 isoform B [KO:K04427] [EC:2.7.11.25]
6932  TCF7; transcription factor 7 isoform 1 [KO:K02620]
6934  TCF7L2; transcription factor 7-like 2 isoform 17 [KO:K04491]
6990  DYNLT3; dynein light chain Tctex-type 3 [KO:K10420]
6993  DYNLT1; dynein light chain Tctex-type 1 isoform 1 [KO:K10420]
7097  TLR2; toll-like receptor 2 precursor [KO:K10159]
7099  TLR4; toll-like receptor 4 isoform A precursor [KO:K10160]
71  ACTG1; actin, cytoplasmic 2 [KO:K05692]
7100  TLR5; toll-like receptor 5 precursor [KO:K10168]
7124  TNF; tumor necrosis factor [KO:K03156]
7132  TNFRSF1A; tumor necrosis factor receptor superfamily member 1A isoform 1 precursor [KO:K03158]
7184  HSP90B1; endoplasmin precursor [KO:K09487]
7186  TRAF2; TNF receptor-associated factor 2 [KO:K03173] [EC:2.3.2.27]
7189  TRAF6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
7277  TUBA4A; tubulin alpha-4A chain isoform 1 [KO:K07374]
7278  TUBA3C; tubulin alpha-3C chain [KO:K07374]
7280  TUBB2A; tubulin beta-2A chain isoform 1 [KO:K07375]
7295  TXN; thioredoxin isoform 1 [KO:K03671]
7846  TUBA1A; tubulin alpha-1A chain isoform 1 [KO:K07374]
7879  RAB7A; ras-related protein Rab-7a [KO:K07897] [EC:3.6.5.2]
79026  AHNAK; neuroblast differentiation-associated protein AHNAK isoform 1 [KO:K23934]
79443  FYCO1; FYVE and coiled-coil domain-containing protein 1 isoform 1 [KO:K21954]
79659  DYNC2H1; cytoplasmic dynein 2 heavy chain 1 isoform 1 [KO:K10414]
79792  GSDMD; gasdermin-D [KO:K20917]
79861  TUBAL3; tubulin alpha chain-like 3 isoform 1 [KO:K07374]
80086  TUBA4B; tubulin-like protein alpha-4B [KO:K07374]
81027  TUBB1; tubulin beta-1 chain [KO:K07375]
81873  ARPC5L; actin-related protein 2/3 complex subunit 5-like protein [KO:K05754]
834  CASP1; caspase-1 isoform alpha precursor [KO:K01370] [EC:3.4.22.36]
83439  TCF7L1; transcription factor 7-like 1 [KO:K04490]
83547  RILP; rab-interacting lysosomal protein [KO:K13883]
836  CASP3; caspase-3 isoform a preproprotein [KO:K02187] [EC:3.4.22.56]
83657  DYNLRB2; dynein light chain roadblock-type 2 isoform 1 [KO:K10419]
83658  DYNLRB1; dynein light chain roadblock-type 1 isoform a [KO:K10419]
837  CASP4; caspase-4 isoform alpha precursor [KO:K04394] [EC:3.4.22.57 3.4.22.64]
838  CASP5; caspase-5 isoform a precursor [KO:K04395] [EC:3.4.22.58]
840  CASP7; caspase-7 isoform alpha precursor [KO:K04397] [EC:3.4.22.60]
841  CASP8; caspase-8 isoform 2 precursor [KO:K04398] [EC:3.4.22.61]
84516  DCTN5; dynactin subunit 5 isoform 1 [KO:K10427]
84617  TUBB6; tubulin beta-6 chain isoform 1 [KO:K07375]
84790  TUBA1C; tubulin alpha-1C chain isoform c [KO:K07374]
8517  IKBKG; NF-kappa-B essential modulator isoform a [KO:K07210]
8655  DYNLL1; dynein light chain 1, cytoplasmic [KO:K10418]
8677  STX10; syntaxin-10 isoform 1 [KO:K23937]
8717  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein [KO:K03171]
8737  RIPK1; receptor-interacting serine/threonine-protein kinase 1 isoform 1 [KO:K02861] [EC:2.7.11.1]
8743  TNFSF10; tumor necrosis factor ligand superfamily member 10 isoform 1 [KO:K04721]
8767  RIPK2; receptor-interacting serine/threonine-protein kinase 2 isoform 1 [KO:K08846] [EC:2.7.11.1]
8772  FADD; FAS-associated death domain protein [KO:K02373]
8795  TNFRSF10B; tumor necrosis factor receptor superfamily member 10B isoform 1 precursor [KO:K04722]
8797  TNFRSF10A; tumor necrosis factor receptor superfamily member 10A [KO:K04722]
8976  WASL; actin nucleation-promoting factor WASL [KO:K23612]
89953  KLC4; kinesin light chain 4 isoform a [KO:K10407]
9265  CYTH3; cytohesin-3 isoform b [KO:K18441]
9266  CYTH2; cytohesin-2 isoform 1 [KO:K18441]
9267  CYTH1; cytohesin-1 isoform 1 [KO:K18441]
929  CD14; monocyte differentiation antigen CD14 precursor [KO:K04391]
93408  MYL10; myosin regulatory light chain 10 [KO:K12756]
9367  RAB9A; ras-related protein Rab-9A [KO:K07899]
9475  ROCK2; rho-associated protein kinase 2 isoform 1 [KO:K17388] [EC:2.7.11.39]
9648  GCC2; GRIP and coiled-coil domain-containing protein 2 isoform 1 [KO:K20282]
9842  PLEKHM1; pleckstrin homology domain-containing family M member 1 isoform 1 [KO:K23282]
9844  ELMO1; engulfment and cell motility protein 1 isoform 1 [KO:K12366]
998  CDC42; cell division control protein 42 homolog isoform 1 precursor [KO:K04393]
Compound
C00338  Lipopolysaccharide
C01194  1-Phosphatidyl-D-myo-inositol
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
Reference
PMID:28875943
  Authors
Bernal-Bayard J, Ramos-Morales F
  Title
Molecular Mechanisms Used by Salmonella to Evade the Immune System.
  Journal
Curr Issues Mol Biol 25:133-168 (2018)
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Related
pathway
hsa04010  MAPK signaling pathway
hsa04064  NF-kappa B signaling pathway
hsa04210  Apoptosis
hsa04217  Necroptosis
hsa04621  NOD-like receptor signaling pathway
KO pathway
ko05132   

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