Vicia sativa

• Index
• Plant Species
• Metabolite list (19)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Vicia sativa
Genus	Vicia
Family	Fabaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Vicia sativa
Linked NCBI taxonomy ID	3908
Linked level	species

Family

Family in NCBI taxonomy	Fabaceae
ID	3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (19)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00002384	Malvin / Malvidin diglucoside / Malvidin 3,5-diglucoside	CHEMBL2009656				No. 1	No. 15
C00005425	Quercetin 3-galactoside-7-rhamnoside	CHEMBL592361 CHEMBL1774171				No. 1	No. 15
C00000931	Zeaxanthin / all-trans-Zeaxanthin	CHEMBL1357855 CHEMBL2359248	C005881	4 / 2 / 3	1 / 0	No. 26	No. 59
C00008580	Taxifolin 4'-methyl ether	CHEMBL451709				No. 42	No. 14
C00001458	Vicianin					No. 128	No. 72
C00002499	Scopoletin	CHEMBL71851	D012603	48 / 37 / 34	9 / 0	No. 864	No. 25
C00002503	Umbelliferon / Umbelliferone / 7-Hydroxycoumarin	CHEMBL51628	C031477	39 / 33 / 32	9 / 0	No. 1030	No. 25
C00001133	Ajugose					No. 1212
C00000576	Xanthotoxin	CHEMBL416	D008730	104 / 55 / 45	22 / 18	No. 1282	No. 25
C00000575	Bergaptan	CHEMBL24171	C022909	22 / 22 / 17	0 / 3	No. 1282	No. 25
C00000103	4-Chloroindole-3-acetic acid methyl ester		C028267			No. 4225
C00000102	4-Chloro-IAA / 4-Chloroindole-3-acetic acid	CHEMBL309993	C096198	1 / 0 / 0		No. 4225
C00001494	Covicine		C007116			No. 4434
C00001515	Vicine		C009661			No. 4434
C00001299	Wyerone					No. 5575	No. 69
C00001431	Spermidine	CHEMBL19612	D013095	26 / 10 / 12	5 / 5	No. 5867
C00001432	Spermine	CHEMBL23194	D013096	35 / 17 / 25	7 / 11	No. 7197
C00001400	Agmatine	CHEMBL58343	D000376	11 / 2 / 3	0 / 9	No. 7327	No. 78
C00001350	L-beta-Cyanoalanine					No. 8372

Human Protein / Gene in interactions

184 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000575 C00000576 C00001400 C00001431 C00001432 C00002499	1 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000575 C00000576 C00001400 C00001431 C00001432 C00002499	0 / 1
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00000575 C00000576 C00001400 C00001431 C00001432 C00002499	1 / 1
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00000575 C00000576 C00001400 C00001431 C00001432 C00002499	0 / 1
P00918	Carbonic anhydrase 2	Lyase	C00000576 C00001431 C00001432 C00002499 C00002503	1 / 2
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00000576 C00001400 C00001431 C00001432 C00002499	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00000931 C00001400 C00001431 C00001432 C00002499	0 / 0
Q16790	Carbonic anhydrase 9	Lyase	C00001431 C00001432 C00002499 C00002503	0 / 1
O43570	Carbonic anhydrase 12	Lyase	C00001431 C00001432 C00002499 C00002503	1 / 2
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00000575 C00001432 C00002499 C00002503	3 / 3
P00915	Carbonic anhydrase 1	Lyase	C00001431 C00001432 C00002499 C00002503	0 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00001432 C00002499 C00002503	1 / 2
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00001431 C00002499 C00002503	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00000575 C00000576 C00002499	7 / 3
O75496	Geminin	Unclassified protein	C00000931 C00002499 C00002503	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00000576 C00002499 C00002503	0 / 3
P83916	Chromobox protein homolog 1	Unclassified protein	C00000575 C00000576 C00002503	0 / 0
P16473	Thyrotropin receptor	Glycohormone receptor	C00000575 C00000576 C00001431	3 / 2
P56817	Beta-secretase 1	A1A	C00000575 C00000576 C00002503	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00000575 C00002499 C00002503	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00000575 C00002499 C00002503	0 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00001400 C00001431 C00001432	0 / 0
O00255	Menin	Unclassified protein	C00001432 C00002499 C00002503	2 / 5
P43166	Carbonic anhydrase 7	Lyase	C00001431 C00001432 C00002499	0 / 0
P29466	Caspase-1	C14	C00000576 C00002499 C00002503	0 / 0
P22303	Acetylcholinesterase	Hydrolase	C00000576 C00002499 C00002503	1 / 0
P35218	Carbonic anhydrase 5A, mitochondrial	Lyase	C00001431 C00001432	0 / 0
Q9Y2D0	Carbonic anhydrase 5B, mitochondrial	Lyase	C00001431 C00001432	0 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00002499 C00002503	1 / 1
Q9H015	Solute carrier family 22 member 4	Unclassified protein	C00001431 C00001432	1 / 1
Q9Y4X1	UDP-glucuronosyltransferase 2A1	Enzyme	C00002499 C00002503	0 / 0
P04062	Glucosylceramidase	Enzyme	C00002499 C00002503	6 / 4
Q9HAW9	UDP-glucuronosyltransferase 1-8	Enzyme	C00002499 C00002503	0 / 0
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00002499 C00002503	2 / 2
Q00796	Sorbitol dehydrogenase	Enzyme	C00002499 C00002503	0 / 0
P20813	Cytochrome P450 2B6	Cytochrome P450 2B6	C00000575 C00000576	1 / 0
P55210	Caspase-7	C14	C00002499 C00002503	0 / 0
Q09470	Potassium voltage-gated channel subfamily A member 1	KCNA, Kv1.x (Shaker)	C00000575 C00000576	1 / 1
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00002499 C00002503	3 / 0
P06280	Alpha-galactosidase A	Enzyme	C00002499 C00002503	1 / 1
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00002499 C00002503	5 / 1
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00002499 C00002503	1 / 1
P10275	Androgen receptor	NR3C4	C00000575 C00000576	3 / 4
P21728	D(1A) dopamine receptor	Dopamine receptor	C00000576 C00001432	0 / 0
P07451	Carbonic anhydrase 3	Lyase	C00001431 C00001432	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00002499 C00002503	1 / 1
P15121	Aldose reductase	Enzyme	C00002499 C00002503	0 / 0
P54855	UDP-glucuronosyltransferase 2B15	Enzyme	C00002499 C00002503	0 / 0
Q9HAW8	UDP-glucuronosyltransferase 1-10	Enzyme	C00002499 C00002503	0 / 0
P22748	Carbonic anhydrase 4	Lyase	C00001431 C00001432	1 / 1
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00000575 C00000576	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00001432 C00002499	0 / 0
P40225	Thrombopoietin	Unclassified protein	C00001431 C00001432	1 / 1
Q9ULX7	Carbonic anhydrase 14	Lyase	C00001431 C00001432	0 / 0
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00001431 C00001432	0 / 0
P23280	Carbonic anhydrase 6	Lyase	C00001431 C00001432	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00000576 C00000931	2 / 3
P04406	Glyceraldehyde-3-phosphate dehydrogenase	Enzyme	C00002499 C00002503	0 / 0
P30988	Calcitonin receptor	Calcitonin receptor	C00000576	0 / 0
Q05586	Glutamate receptor ionotropic, NMDA 1	NS	C00001432	1 / 0
Q12879	Glutamate receptor ionotropic, NMDA 2A	NS	C00001432	0 / 0
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00000576	1 / 8
Q08209	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Ser_Thr	C00000576	0 / 0
P14416	D(2) dopamine receptor	Dopamine receptor	C00000576	2 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00000576	0 / 0
P37288	Vasopressin V1a receptor	Vasopressin and oxytocin receptor	C00000576	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00000576	0 / 0
Q9Y271	Cysteinyl leukotriene receptor 1	Leukotriene receptor	C00000576	0 / 0
P29274	Adenosine receptor A2a	Adenosine receptor	C00000576	0 / 0
P06241	Tyrosine-protein kinase Fyn	Src	C00000576	0 / 0
P42575	Caspase-2	C14	C00001432	0 / 0
P25929	Neuropeptide Y receptor type 1	Neuropeptide Y receptor	C00000576	0 / 0
P16389	Potassium voltage-gated channel subfamily A member 2	KCNA, Kv1.x (Shaker)	C00000575	0 / 0
P50052	Type-2 angiotensin II receptor	Angiotensin receptor	C00000576	1 / 1
P25024	C-X-C chemokine receptor type 1	CXC chemokine receptor	C00000576	0 / 0
P17948	Vascular endothelial growth factor receptor 1	Vegfr	C00000576	0 / 0
P41968	Melanocortin receptor 3	Melanocortin receptor	C00000576	1 / 0
P08183	Multidrug resistance protein 1	drug	C00000575	1 / 0
P02768	Serum albumin	Secreted protein	C00000102	0 / 0
P28845	Corticosteroid 11-beta-dehydrogenase isozyme 1	Enzyme	C00002503	1 / 1
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00000576	0 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00000576	0 / 0
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00002499	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00002503	0 / 0
P08912	Muscarinic acetylcholine receptor M5	Acetylcholine receptor	C00000576	0 / 0
Q01959	Sodium-dependent dopamine transporter	Dopamine	C00000576	1 / 0
O60656	UDP-glucuronosyltransferase 1-9	Enzyme	C00002499	0 / 0
P35367	Histamine H1 receptor	Histamine receptor	C00000576	0 / 0
P04035	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oxidoreductase	C00000576	0 / 0
P08913	Alpha-2A adrenergic receptor	Adrenergic receptor	C00000576	0 / 0
P18405	3-oxo-5-alpha-steroid 4-dehydrogenase 1	Oxidoreductase	C00002503	0 / 0
P21917	D(4) dopamine receptor	Dopamine receptor	C00000576	0 / 0
P23443	Ribosomal protein S6 kinase beta-1	p70	C00000576	0 / 0
P35462	D(3) dopamine receptor	Dopamine receptor	C00000576	1 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00000576	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00000576	0 / 1
P41595	5-hydroxytryptamine receptor 2B	Serotonin receptor	C00000576	0 / 0
P25021	Histamine H2 receptor	Histamine receptor	C00000576	0 / 0
P25101	Endothelin-1 receptor	Endothelin receptor	C00000576	0 / 0
P30411	B2 bradykinin receptor	Bradykinin receptor	C00000576	0 / 0
P32245	Melanocortin receptor 4	Melanocortin receptor	C00000576	1 / 0
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00000576	1 / 1
Q6QHF9	Peroxisomal N(1)-acetyl-spermine/spermidine oxidase	Enzyme	C00001431	0 / 0
P32238	Cholecystokinin receptor type A	Cholecystokinin receptor	C00000576	0 / 0
P08311	Cathepsin G	S1A	C00000576	0 / 0
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00000576	1 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00000576	0 / 0
P03956	Interstitial collagenase	M10A	C00000576	0 / 1
P32241	Vasoactive intestinal polypeptide receptor 1	Vasoactive intestinal peptide receptor	C00000576	0 / 0
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00000576	0 / 1
Q04206	Transcription factor p65	Transcription Factor	C00002499	0 / 0
P42574	Caspase-3	C14	C00001432	0 / 0
Q9NPD5	Solute carrier organic anion transporter family member 1B3	Electrochemical transporter	C00000576	1 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00000931	0 / 0
P04150	Glucocorticoid receptor	NR3C1	C00000576	0 / 1
P08172	Muscarinic acetylcholine receptor M2	Acetylcholine receptor	C00000576	2 / 0
P11229	Muscarinic acetylcholine receptor M1	Acetylcholine receptor	C00000576	0 / 0
P14679	Tyrosinase	Oxidoreductase	C00002503	4 / 2
P21554	Cannabinoid receptor 1	Cannabinoid receptor	C00000576	0 / 0
P31645	Sodium-dependent serotonin transporter	Serotonin	C00000576	2 / 0
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00000576	5 / 9
P20309	Muscarinic acetylcholine receptor M3	Acetylcholine receptor	C00000576	1 / 0
P21452	Substance-K receptor	Neurokinin receptor	C00000576	0 / 0
P51679	C-C chemokine receptor type 4	CC chemokine receptor	C00000576	0 / 0
P51681	C-C chemokine receptor type 5	CC chemokine receptor	C00000576	3 / 0
P50406	5-hydroxytryptamine receptor 6	Serotonin receptor	C00000576	0 / 0
P55789	FAD-linked sulfhydryl oxidase ALR	Enzyme	C00002499	1 / 0
P41597	C-C chemokine receptor type 2	CC chemokine receptor	C00000576	1 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00000576	0 / 0
P08575	Receptor-type tyrosine-protein phosphatase C	Enzyme	C00000576	2 / 1
Q8TD43	Transient receptor potential cation channel subfamily M member 4	Unclassified protein	C00001432	1 / 1
O15245	Solute carrier family 22 member 1	Drug uniporter	C00001400	0 / 0
P17658	Potassium voltage-gated channel subfamily A member 6	K	C00000575	0 / 0
Q8N1Q1	Carbonic anhydrase 13	Lyase	C00002499	0 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00002499	0 / 0
P51449	Nuclear receptor ROR-gamma	Nuclear hormone receptor subfamily 1 group F member 3	C00000576	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00001431	0 / 0
P14780	Matrix metalloproteinase-9	M10A	C00000576	2 / 2
P27361	Mitogen-activated protein kinase 3	Erk	C00000576	0 / 0
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00000576	0 / 0
P03372	Estrogen receptor	NR3A1	C00000576	1 / 1
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00000576	1 / 0
P17252	Protein kinase C alpha type	Alpha	C00000576	0 / 0
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00000576	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00000576	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00000576	0 / 0
P08173	Muscarinic acetylcholine receptor M4	Acetylcholine receptor	C00000576	0 / 0
P25103	Substance-P receptor	Neurokinin receptor	C00000576	0 / 0
P25105	Platelet-activating factor receptor	PAF receptor	C00000576	0 / 0
P33032	Melanocortin receptor 5	Melanocortin receptor	C00000576	0 / 0
P22001	Potassium voltage-gated channel subfamily A member 3	KCNA, Kv1.x (Shaker)	C00000575	0 / 0
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00001400	0 / 0
P49146	Neuropeptide Y receptor type 2	Neuropeptide Y receptor	C00000576	0 / 0
P61073	C-X-C chemokine receptor type 4	CXC chemokine receptor	C00001432	1 / 1
Q16539	Mitogen-activated protein kinase 14	p38	C00000576	0 / 0
P33765	Adenosine receptor A3	Adenosine receptor	C00000576	0 / 0
P05181	Cytochrome P450 2E1	Cytochrome P450 2E1	C00000576	0 / 0
P08246	Neutrophil elastase	S1A	C00000576	2 / 1
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00000575	0 / 0
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00000576	2 / 2
P23975	Sodium-dependent noradrenaline transporter	Norepinephrine	C00000576	1 / 1
P25100	Alpha-1D adrenergic receptor	Adrenergic receptor	C00000576	0 / 0
P30542	Adenosine receptor A1	Adenosine receptor	C00000576	0 / 0
P18089	Alpha-2B adrenergic receptor	Adrenergic receptor	C00000576	0 / 0
P24557	Thromboxane-A synthase	Cytochrome P450 5A1	C00000576	1 / 1
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00002499	0 / 0
P06239	Tyrosine-protein kinase Lck	Src	C00000576	0 / 1
P22460	Potassium voltage-gated channel subfamily A member 5	KCNA, Kv1.x (Shaker)	C00000575	1 / 1
P25025	C-X-C chemokine receptor type 2	CXC chemokine receptor	C00000576	0 / 0
O94956	Solute carrier organic anion transporter family member 2B1	Unclassified protein	C00000576	0 / 0
P80365	Corticosteroid 11-beta-dehydrogenase isozyme 2	Enzyme	C00002503	1 / 1
O15244	Solute carrier family 22 member 2	Drug uniporter	C00001400	0 / 0
Q9Y6L6	Solute carrier organic anion transporter family member 1B1	Electrochemical transporter	C00000576	1 / 0
Q9NZQ8	Transient receptor potential cation channel subfamily M member 5	Unclassified protein	C00001432	0 / 0
P48547	Potassium voltage-gated channel subfamily C member 1	K	C00000575	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00002503	1 / 1
O75795	UDP-glucuronosyltransferase 2B17	Enzyme	C00002499	1 / 0
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00002499	0 / 0
Q13951	Core-binding factor subunit beta	Unclassified protein	C00001432	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00001432	1 / 4
P42345	Serine/threonine-protein kinase mTOR	Enzyme	C00001431	0 / 0
O75751	Solute carrier family 22 member 3	Unclassified protein	C00001400	0 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00002503	0 / 0
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00000576	1 / 1

44 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00000576 C00001432 C00002503
581	BAX, BCL2L4	BCL2-associated X protein	C00000576 C00002503
153	ADRB1, ADRB1R, B1AR, BETA1AR, RHR	adrenoceptor beta 1	C00001431 C00001432
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00000576 C00001431
154	ADRB2, ADRB2R, ADRBR, B2AR, BAR, BETA2AR	adrenoceptor beta 2, surface	C00001431 C00001432
7366	UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8	UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17)	C00002499 C00002503
1548	CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB	cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1)	C00000576 C00002503
54600	UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I	UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17)	C00002499 C00002503
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00000576
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00002503
8553	BHLHE40, BHLHB2, DEC1, HLHB2, SHARP-2, STRA13, Stra14	basic helix-loop-helix family, member e40	C00000576
332	BIRC5, API4, EPR-1	baculoviral IAP repeat containing 5	C00000576
2950	GSTP1, DFN7, FAEES3, GST3, GSTP, PI	glutathione S-transferase pi 1 (EC:2.5.1.18)	C00000931
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00000576
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00000576
1027	CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	C00000576
8824	CES2, CE-2, CES2A1, PCE-2, iCE	carboxylesterase 2 (EC:3.1.1.1 3.1.1.84 3.1.1.56)	C00000576
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00000576
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00000576
1553	CYP2A13, CPAD, CYP2A, CYPIIA13	cytochrome P450, family 2, subfamily A, polypeptide 13 (EC:1.14.14.1)	C00000576
1559	CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9	cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00000576
1565	CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1	cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1)	C00000576
6817	SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1)	C00002503
3034	HAL, HIS, HSTD	histidine ammonia-lyase (EC:4.3.1.3)	C00000576
8856	NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR	nuclear receptor subfamily 1, group I, member 2	C00000576
3355109			C00000576
5925	RB1, OSRC, RB, p105-Rb, pRb, pp110	retinoblastoma 1	C00000576
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00000576
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00000576
54658	UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A	UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17)	C00002499
54575	UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J	UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17)	C00002499
54659	UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C	UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17)	C00002499
54578	UGT1A6, GNT1, HLUGP, HLUGP1, UDPGT, UDPGT_1-6, UGT1, UGT1A6S, UGT1F	UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17)	C00002499
54577	UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G	UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17)	C00002499
54576	UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H	UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17)	C00002499
7508	XPC, RAD4, XP3, XPCC	xeroderma pigmentosum, complementation group C	C00002499
8574	AKR7A2, AFAR, AFAR1, AFB1-AR1, AKR7	aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) (EC:1.1.1.n11)	C00002503
8644	AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS	aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357)	C00002503
486	FXYD2, ATP1G1, HOMG2	FXYD domain containing ion transport regulator 2	C00001431
331	XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3	X-linked inhibitor of apoptosis	C00001431
846	CASR, CAR, EIG8, FHH, FIH, GPRC2A, HHC, HHC1, HYPOC1, NSHPT, PCAR1	calcium-sensing receptor	C00001432
56616	DIABLO, DFNA64, SMAC	diablo, IAP-binding mitochondrial protein	C00001432
5599	MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c	mitogen-activated protein kinase 8 (EC:2.7.11.24)	C00001432
4843	NOS2, HEP-NOS, INOS, NOS, NOS2A	nitric oxide synthase 2, inducible (EC:1.14.13.39)	C00001432

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