Ginkgo biloba
Species
KNApSAcK Entry
| Organism name | Ginkgo biloba |
|---|---|
| Genus | Ginkgo |
| Family | Ginkgoaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Ginkgo biloba |
|---|---|
| Linked NCBI taxonomy ID | 3311 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Ginkgoaceae |
|---|---|
| ID | 3309 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | Spermatophyta |
|---|---|
| ID | 58024 |
Metabolite list (41)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00005417
|
Quercetin 3-glucosyl-(1->2)-rhamnoside
|
No. 1 | No. 15 |
|
||||
|
C00005765
|
Laricitrin 3-rutinoside
|
No. 1 | No. 15 |
|
||||
|
C00005737
|
Myricetin 3-rutinoside
/ Myricetin-3-O-rutinoside |
No. 1 | No. 15 |
|
||||
|
C00005413
|
Rutin
/ Birutan / 3-Rutinosylquercetin / Quercetin 3-O-rutinoside / (+)-Quercetin 3-O-rutinoside / Quercetin 3-O-beta-rutinoside / (+)-Quercetin 3-O-beta-rutinoside / 3,3',4',5,7-Pentahydroxyflavone 3-rutinoside / Quercetin 3-O-alpha-L-rhamnopyranosyl-(1->6)-beta-D-glucopyranoside |
CHEMBL32579
CHEMBL310754 CHEMBL182108 CHEMBL226335 CHEMBL502782 CHEMBL1436093 CHEMBL1532989 |
D012431
|
25 / 18 / 16 | 29 / 8 | No. 1 | No. 15 |
|
|
C00005171
|
Kaempferol 3-glucosyl-(1->2)-rhamnoside
/ 3-[(6-Deoxy-2-O-beta-D-glucopyranosyl-alpha-L-mannopyranosyl)oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
C074176
|
No. 1 | No. 15 |
|
|||
|
C00005373
|
Hirsutrin
/ Isoquercetin / Isoquercetrin / (-)-Isoquercetrin / Quercetin 3-glucoside / Quercetin 3-O-beta-D-glucoside / Quercetin-3-O-beta-D-glucopyranoside / Quercetin 3-O-beta-D-glucopyranoside / (-)-Quercetin-3-O-beta-D-glucopyranoside |
CHEMBL33027
CHEMBL309323 CHEMBL250450 CHEMBL251254 CHEMBL457304 CHEMBL1098724 CHEMBL2337335 CHEMBL2337336 |
38 / 43 / 34 | No. 2 | No. 15 |
|
||
|
C00005573
|
Typhaneoside
|
CHEMBL450526
|
C051428
|
No. 5 | No. 15 |
|
||
|
C00005456
|
Manghaslin
/ Quercetin 3-2G-rhamnosylrutinoside |
CHEMBL444468
|
No. 5 | No. 15 |
|
|||
|
C00005978
|
Quercetin 3-(6'''-p-coumarylglucosyl)(1->2)-rhamnoside
|
No. 7 | No. 15 |
|
||||
|
C00005979
|
Quercetin 3-(6-[4-glucosyl-p-coumaryl]glucosyl)(1->2)-rhamnoside
|
No. 7 | No. 15 |
|
||||
|
C00013920
|
Isorhamnetin 3-(6'''-p-coumaroylglucosyl)-(1->2)-rhamnoside
/ Quercetin 3'-methyl ether 3-(6'''-p-coumaroylglucosyl)-(1->2)-rhamnoside / 3-[[6-Deoxy-2-O-[6-O-[3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-beta-D-glucopyranosyl]-alpha-L-mannopyranosyl]oxy]-5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one |
No. 7 | No. 15 |
|
||||
|
C00005885
|
Kaempferol 3-(6-[4-glucosyl-p-coumaryl]glucosyl)(1->2)-rhamnoside
|
No. 7 | No. 15 |
|
||||
|
C00005884
|
Kaempferol 3-[6'''-p-coumarylglucosyl-(1->2)-rhamnoside]
|
No. 7 | No. 15 |
|
||||
|
C00013798
|
Kaempferol 3-(6'''-p-coumaroylglucosyl)-(1->2)-rhamnoside-7-glucoside
/ 3-[[6-Deoxy-2-O-[6-O-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-beta-D-glucopyranosyl]-alpha-L-mannopyranosyl]oxy]-7-(beta-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
No. 7 | No. 15 |
|
||||
|
C00006000
|
Quercetin 3-(6'''-p-coumarylglucosyl)(1->2)-rhamnoside-7-glucoside
|
No. 7 | No. 15 |
|
||||
|
C00001044
|
Ginkgetin
/ 7,4'-Dimethylamentoflavone / Amentoflavone 7'',4'''-dimethyl ether |
CHEMBL377324
|
C077458
|
1 / 0 / 0 | No. 34 | No. 18 |
|
|
|
C00006488
|
Bilobetin
|
CHEMBL378188
|
2 / 1 / 2 | No. 34 | No. 18 |
|
||
|
C00001098
|
Sciadopitysin
|
CHEMBL208908
|
C086243
|
3 / 3 / 7 | No. 34 | No. 18 |
|
|
|
C00006497
|
5'-Methoxybilobetin
|
No. 34 | No. 18 |
|
||||
|
C00006494
|
Isoginkgetin
|
CHEMBL1208903
|
10 / 32 / 61 | No. 34 | No. 18 |
|
||
|
C00002631
|
(+)-Lirioresinol B
/ (+)-Syringaresinol |
CHEMBL361362
CHEMBL402653 |
C042192
|
1 / 0 / 0 | No. 38 | No. 21 |
|
|
|
C00000947
|
D-Catechol
/ D-Catechin / Teafuran 30A / (+)-Catechin / Dexcyanidanol / (+)-3',4',5,7-Tetrahydroxy-2,3-trans-flavan-3-ol |
CHEMBL80941
CHEMBL311498 CHEMBL129482 CHEMBL200715 CHEMBL206452 CHEMBL583912 |
D002392
|
85 / 58 / 54 | 91 / 13 | No. 52 | No. 14 |
|
|
C00008817
|
Gallocatechin
/ (+)-Gallocatechin / (+)-Gallocatechol / (2R,3S)-3,4-Dihydro-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3,5,7-triol |
CHEMBL47386
CHEMBL125743 CHEMBL130415 CHEMBL264167 CHEMBL404845 |
26 / 17 / 29 | No. 52 | No. 14 |
|
||
|
C00000956
|
(-)-Epicatechin
|
CHEMBL80941
CHEMBL311498 CHEMBL129482 CHEMBL200715 CHEMBL206452 CHEMBL583912 |
85 / 58 / 54 | No. 52 | No. 14 |
|
||
|
C00008818
|
Epigallocatechin
/ (-)-Epigallocatechin |
CHEMBL47386
CHEMBL125743 CHEMBL130415 CHEMBL264167 CHEMBL404845 |
26 / 17 / 29 | No. 52 | No. 14 |
|
||
|
C00001261
|
Nonacosan-10-ol
|
No. 115 |
|
|||||
|
C00000601
|
(+)-Sesamin
|
CHEMBL43469
CHEMBL252915 CHEMBL1572261 CHEMBL1591714 CHEMBL1708854 CHEMBL1904496 CHEMBL1968861 |
C054125
|
20 / 24 / 15 | 0 / 5 | No. 621 | No. 21 |
|
|
C00002640
|
Bilobol
|
C064011
|
No. 652 |
|
||||
|
C00011644
|
(Z)-alpha-Atlantone
/ [R-(Z)]-2-Methyl-6-(4-methyl-3-cyclohexen-1-yl)-2,5-heptadien-4-one |
No. 1323 | No. 38 |
|
||||
|
C00035832
|
Ginkgolide J
|
CHEMBL2112172
|
C075228
|
1 / 0 / 0 | 1 / 0 | No. 2137 | No. 44 |
|
|
C00041545
|
Ginkgolide M
|
No. 2137 | No. 44 |
|
||||
|
C00035830
|
Ginkgolide B
|
CHEMBL514432
CHEMBL1434825 CHEMBL1515002 CHEMBL1898434 |
17 / 21 / 17 | No. 2137 | No. 44 |
|
||
|
C00035831
|
Ginkgolide C
|
CHEMBL156251
CHEMBL347488 CHEMBL375821 CHEMBL1299408 CHEMBL1596335 CHEMBL1868593 CHEMBL2112173 |
C058295
|
8 / 1 / 1 | 3 / 0 | No. 2137 | No. 44 |
|
|
C00003429
|
Ginkgolide A
|
CHEMBL465161
CHEMBL1370614 CHEMBL1408113 CHEMBL1472160 CHEMBL1712596 CHEMBL1741996 CHEMBL2112174 |
13 / 10 / 12 | No. 2137 | No. 44 |
|
||
|
C00011645
|
(Z)-6-Methyl-2-(4-methyl-3-cyclohexen-1-yl)-2-hepten-4-one
|
No. 2249 |
|
|||||
|
C00011643
|
(E)-6-Methyl-2-(4-methyl-3-cyclohexen-1-yl)-2-hepten-4-one
|
No. 2249 |
|
|||||
|
C00047902
|
Ginkgotoxin
|
CHEMBL1076875
|
C001737
|
3 / 1 / 1 | No. 2457 |
|
||
|
C00011591
|
Bilobanon
/ Bilobanone |
No. 3255 |
|
|||||
|
C00002651
|
Ginkgoic acid
|
CHEMBL277156
CHEMBL445177 |
C112485
|
11 / 9 / 9 | No. 3375 | No. 84 |
|
|
|
C00011512
|
Bilobalide
|
CHEMBL133266
CHEMBL1318117 |
C073710
|
11 / 18 / 15 | 3 / 1 | No. 6166 | No. 44 |
|
|
C00011601
|
(E)-5-(1,5-Dimethyl-3-oxo-1-hexenyl)-2-methyl-2-cyclohexen-1-one
|
No. 7498 |
|
Human Protein / Gene in interactions
132 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00000601 C00000947 C00000956 C00002651 C00005373 C00005413 C00006494 C00008817 C00008818 | 4 / 3 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00000947 C00000956 C00002651 C00005373 C00005413 C00008817 C00008818 C00035831 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00000947 C00000956 C00005373 C00005413 C00008817 C00008818 C00035830 C00035831 | 0 / 0 |
| P56817 | Beta-secretase 1 | A1A | C00000947 C00000956 C00001044 C00001098 C00006488 C00006494 C00008817 C00008818 | 0 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00000601 C00000947 C00000956 C00002651 C00005413 C00006494 C00008817 C00008818 | 0 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00000947 C00000956 C00002651 C00005413 C00006494 C00008817 C00008818 C00035830 | 3 / 3 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00000601 C00000947 C00000956 C00002651 C00008817 C00008818 C00035830 | 2 / 3 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00000947 C00000956 C00002651 C00005373 C00005413 C00008817 C00008818 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000601 C00000947 C00000956 C00003429 C00005413 C00006494 C00035830 | 0 / 1 |
| O00255 | Menin | Unclassified protein | C00000947 C00000956 C00001098 C00003429 C00006494 C00011512 | 2 / 5 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00000601 C00000947 C00000956 C00005373 C00005413 C00035831 | 0 / 0 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00000947 C00000956 C00001098 C00003429 C00006494 C00011512 | 1 / 2 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00000947 C00000956 C00005373 C00005413 C00008817 C00008818 | 0 / 3 |
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00000947 C00000956 C00005373 C00005413 C00008817 C00008818 | 1 / 1 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00000601 C00000947 C00000956 C00003429 C00005373 C00011512 | 4 / 1 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00000947 C00000956 C00002651 C00008817 C00008818 C00011512 | 0 / 0 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00000601 C00000947 C00000956 C00008817 C00008818 | 2 / 2 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000601 C00000947 C00000956 C00003429 C00035830 | 0 / 1 |
| P41145 | Kappa-type opioid receptor | Opioid receptor | C00000947 C00000956 C00005373 C00008817 C00008818 | 0 / 0 |
| P41143 | Delta-type opioid receptor | Opioid receptor | C00000947 C00000956 C00005373 C00008817 C00008818 | 0 / 0 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00000947 C00000956 C00005373 C00008817 C00008818 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000601 C00000947 C00000956 C00003429 C00035830 | 1 / 1 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000601 C00000947 C00000956 C00003429 C00035830 | 1 / 0 |
| O75496 | Geminin | Unclassified protein | C00000601 C00005373 C00011512 C00035830 C00035831 | 0 / 0 |
| P25105 | Platelet-activating factor receptor | PAF receptor | C00003429 C00035830 C00035831 C00035832 | 0 / 0 |
| P00374 | Dihydrofolate reductase | Oxidoreductase | C00000947 C00000956 C00008817 C00008818 | 1 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00000601 C00000947 C00000956 C00005373 | 0 / 0 |
| P52209 | 6-phosphogluconate dehydrogenase, decarboxylating | Enzyme | C00000947 C00000956 C00008817 C00008818 | 0 / 0 |
| P02768 | Serum albumin | Secreted protein | C00000947 C00000956 C00008817 C00008818 | 0 / 0 |
| P10415 | Apoptosis regulator Bcl-2 | Other cytosolic protein | C00000947 C00000956 C00008817 C00008818 | 0 / 7 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00000947 C00000956 C00003429 C00035830 | 0 / 0 |
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00000947 C00000956 C00005373 C00005413 | 1 / 1 |
| P06746 | DNA polymerase beta | Enzyme | C00000947 C00000956 C00005373 C00005413 | 0 / 0 |
| P23416 | Glycine receptor subunit alpha-2 | GLR alpha | C00003429 C00011512 C00035830 C00035831 | 0 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00000947 C00000956 C00008817 C00008818 | 0 / 0 |
| P08581 | Hepatocyte growth factor receptor | TK tyrosine-protein kinase MET subfamily | C00000947 C00000956 C00008817 C00008818 | 2 / 3 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00005373 C00008817 C00008818 C00011512 | 1 / 4 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00000947 C00000956 C00003429 C00005373 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00000947 C00000956 C00008817 C00008818 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00000947 C00000956 C00005373 C00005413 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00000947 C00000956 C00008817 C00008818 | 1 / 1 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00000601 C00011512 C00035830 C00035831 | 0 / 0 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00005373 C00008817 C00008818 C00011512 | 0 / 1 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00000947 C00000956 C00008817 C00008818 | 0 / 0 |
| P09923 | Intestinal-type alkaline phosphatase | Enzyme | C00000947 C00000956 C00005373 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00000601 C00000947 C00000956 | 2 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00000947 C00000956 C00005373 | 1 / 1 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00000601 C00011512 C00035830 | 7 / 3 |
| P11388 | DNA topoisomerase 2-alpha | Isomerase | C00000947 C00000956 C00005413 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00000947 C00000956 C00005373 | 0 / 0 |
| P10696 | Alkaline phosphatase, placental-like | Enzyme | C00000947 C00000956 C00005373 | 0 / 1 |
| P23415 | Glycine receptor subunit alpha-1 | GLR alpha | C00003429 C00035830 C00035831 | 1 / 1 |
| P05186 | Alkaline phosphatase, tissue-nonspecific isozyme | Enzyme | C00000947 C00000956 C00005373 | 3 / 1 |
| P07998 | Ribonuclease pancreatic | Enzyme | C00000947 C00000956 | 0 / 0 |
| Q9H0H5 | Rac GTPase-activating protein 1 | Unclassified protein | C00000947 C00000956 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00002651 C00035830 | 0 / 0 |
| Q15139 | Serine/threonine-protein kinase D1 | Pkd | C00000947 C00000956 | 0 / 0 |
| P41743 | Protein kinase C iota type | Iota | C00000947 C00000956 | 0 / 0 |
| P24723 | Protein kinase C eta type | Eta | C00000947 C00000956 | 1 / 0 |
| P00915 | Carbonic anhydrase 1 | Lyase | C00000947 C00000956 | 0 / 0 |
| P07711 | Cathepsin L1 | C1A | C00000947 C00000956 | 0 / 0 |
| P05771 | Protein kinase C beta type | Alpha | C00000947 C00000956 | 0 / 0 |
| P05129 | Protein kinase C gamma type | Alpha | C00000947 C00000956 | 1 / 1 |
| O43570 | Carbonic anhydrase 12 | Lyase | C00000947 C00000956 | 1 / 2 |
| Q05655 | Protein kinase C delta type | Delta | C00000947 C00000956 | 0 / 0 |
| Q9ULX7 | Carbonic anhydrase 14 | Lyase | C00000947 C00000956 | 0 / 0 |
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00000601 C00002651 | 0 / 0 |
| Q9Y3R4 | Sialidase-2 | Enzyme | C00000947 C00000956 | 0 / 0 |
| P17252 | Protein kinase C alpha type | Alpha | C00000947 C00000956 | 0 / 0 |
| O94806 | Serine/threonine-protein kinase D3 | Pkd | C00000947 C00000956 | 0 / 0 |
| P23280 | Carbonic anhydrase 6 | Lyase | C00000947 C00000956 | 0 / 0 |
| P00734 | Prothrombin | S1A | C00000947 C00000956 | 4 / 2 |
| P14679 | Tyrosinase | Oxidoreductase | C00005373 C00005413 | 4 / 2 |
| Q02156 | Protein kinase C epsilon type | Eta | C00000947 C00000956 | 0 / 0 |
| Q04759 | Protein kinase C theta type | Delta | C00000947 C00000956 | 0 / 1 |
| P04745 | Alpha-amylase 1 | Enzyme | C00000947 C00000956 | 0 / 0 |
| Q05513 | Protein kinase C zeta type | Iota | C00000947 C00000956 | 0 / 0 |
| P22310 | UDP-glucuronosyltransferase 1-4 | Enzyme | C00000947 C00000956 | 3 / 0 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00005373 C00005413 | 1 / 0 |
| P54132 | Bloom syndrome protein | Enzyme | C00000947 C00000956 | 1 / 2 |
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00000947 C00000956 | 0 / 0 |
| P49327 | Fatty acid synthase | Transferase | C00000947 C00000956 | 0 / 0 |
| Q16790 | Carbonic anhydrase 9 | Lyase | C00000947 C00000956 | 0 / 1 |
| Q13093 | Platelet-activating factor acetylhydrolase | Enzyme | C00000947 C00000956 | 3 / 0 |
| Q9UNQ0 | ATP-binding cassette sub-family G member 2 | ATP binding cassette | C00005373 C00005413 | 2 / 0 |
| P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | C00005373 C00005413 | 0 / 0 |
| Q01453 | Peripheral myelin protein 22 | Unclassified protein | C00000947 C00000956 | 5 / 2 |
| P22309 | UDP-glucuronosyltransferase 1-1 | Enzyme | C00000947 C00000956 | 5 / 1 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00000947 C00000956 | 1 / 2 |
| Q9Y2D0 | Carbonic anhydrase 5B, mitochondrial | Lyase | C00000947 C00000956 | 0 / 0 |
| P35218 | Carbonic anhydrase 5A, mitochondrial | Lyase | C00000947 C00000956 | 0 / 0 |
| P22748 | Carbonic anhydrase 4 | Lyase | C00000947 C00000956 | 1 / 1 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00000947 C00000956 | 3 / 2 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00000947 C00000956 | 0 / 0 |
| P07451 | Carbonic anhydrase 3 | Lyase | C00000947 C00000956 | 0 / 0 |
| P43166 | Carbonic anhydrase 7 | Lyase | C00000947 C00000956 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00005373 C00006494 | 11 / 10 |
| P28907 | ADP-ribosyl cyclase 1 | Enzyme | C00000947 C00000956 | 0 / 1 |
| Q6W5P4 | Neuropeptide S receptor | Neuropeptide receptor | C00000947 C00000956 | 1 / 0 |
| Q8N1Q1 | Carbonic anhydrase 13 | Lyase | C00000947 C00000956 | 0 / 0 |
| P04062 | Glucosylceramidase | Enzyme | C00005373 C00035830 | 6 / 4 |
| O00764 | Pyridoxal kinase | Enzyme | C00047902 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00000601 | 0 / 0 |
| P08908 | 5-hydroxytryptamine receptor 1A | Serotonin receptor | C00005373 | 1 / 0 |
| O75311 | Glycine receptor subunit alpha-3 | GLR alpha | C00035830 | 0 / 0 |
| Q99259 | Glutamate decarboxylase 1 | Enzyme | C00047902 | 1 / 1 |
| P34949 | Mannose-6-phosphate isomerase | Enzyme | C00005373 | 1 / 1 |
| P48147 | Prolyl endopeptidase | S9A | C00005413 | 0 / 0 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00011512 | 3 / 1 |
| P22303 | Acetylcholinesterase | Hydrolase | C00005413 | 1 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00005413 | 1 / 1 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00000601 | 0 / 0 |
| Q05329 | Glutamate decarboxylase 2 | Enzyme | C00047902 | 0 / 0 |
| Q9NPH5 | NADPH oxidase 4 | Enzyme | C00005373 | 0 / 0 |
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00006494 | 7 / 37 |
| P07237 | Protein disulfide-isomerase | Enzyme | C00005373 | 0 / 0 |
| P11387 | DNA topoisomerase 1 | Isomerase | C00002631 | 0 / 0 |
| P33527 | Multidrug resistance-associated protein 1 | drugs | C00005413 | 0 / 0 |
| P13726 | Tissue factor | Membrane receptor | C00002651 | 0 / 0 |
| P06280 | Alpha-galactosidase A | Enzyme | C00005373 | 1 / 1 |
| P06276 | Cholinesterase | Hydrolase | C00005413 | 0 / 0 |
| P11021 | 78 kDa glucose-regulated protein | Unclassified protein | C00003429 | 0 / 0 |
| P43235 | Cathepsin K | C1A | C00006488 | 1 / 2 |
| P68871 | Hemoglobin subunit beta | Secreted protein | C00006494 | 4 / 4 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00000601 | 0 / 0 |
| P27487 | Dipeptidyl peptidase 4 | S9B | C00005413 | 0 / 1 |
| P15121 | Aldose reductase | Enzyme | C00005373 | 0 / 0 |
| P36888 | Receptor-type tyrosine-protein kinase FLT3 | Pdgfr | C00005373 | 1 / 1 |
| P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | C00005413 | 0 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00005373 | 0 / 0 |
| Q9UBE0 | SUMO-activating enzyme subunit 1 | Unclassified protein | C00002651 | 0 / 0 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00000601 | 1 / 1 |
109 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00000947
C00005413
C00011512
C00035831
C00035832 |
| 5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00000947
C00005413
|
| 351 | APP, AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2 | amyloid beta (A4) precursor protein |
C00011512
C00035831
|
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00000947
C00005413
|
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00000947
C00005413
|
| 5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00000947
C00005413
|
| 4792 | NFKBIA, IKBA, MAD-3, NFKBI | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
C00000947
C00005413
|
| 1385 | CREB1, CREB | cAMP responsive element binding protein 1 |
C00011512
C00035831
|
| 5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00000947
C00005413
|
| 3553 | IL1B, IL-1, IL1-BETA, IL1F2 | interleukin 1, beta |
C00000947
C00005413
|
| 3627 | CXCL10, C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1 | chemokine (C-X-C motif) ligand 10 |
C00000947
C00005413
|
| 581 | BAX, BCL2L4 | BCL2-associated X protein |
C00000947
C00005413
|
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00000947
C00005413
|
| 6347 | CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF | chemokine (C-C motif) ligand 2 |
C00000947
C00005413
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00000947
C00005413
|
| 6772 | STAT1, CANDF7, ISGF-3, STAT91 | signal transducer and activator of transcription 1, 91kDa |
C00000947
|
| 694 | BTG1 | B-cell translocation gene 1, anti-proliferative |
C00000947
|
| 388962 | BOLA3, MMDS2 | bolA family member 3 |
C00000947
|
| 840 | CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 | caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) |
C00000947
|
| 841 | CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 | caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) |
C00000947
|
| 842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00000947
|
| 637 | BID, FP497 | BH3 interacting domain death agonist |
C00000947
|
| 595 | CCND1, BCL1, D11S287E, PRAD1, U21B31 | cyclin D1 |
C00000947
|
| 930 | CD19, B4, CVID3 | CD19 molecule |
C00000947
|
| 975 | CD81, CVID6, S5.7, TAPA1, TSPAN28 | CD81 molecule |
C00000947
|
| 928 | CD9, BTCC-1, DRAP-27, MIC3, MRP-1, TSPAN-29, TSPAN29 | CD9 molecule |
C00000947
|
| 1054 | CEBPG, GPE1BP, IG/EBP-1 | CCAAT/enhancer binding protein (C/EBP), gamma |
C00000947
|
| 10978 | CLP1, HEAB, hClp1 | cleavage and polyadenylation factor I subunit 1 (EC:2.7.1.78) |
C00000947
|
| 10063 | COX17 | COX17 cytochrome c oxidase copper chaperone |
C00000947
|
| 56751 | BARHL1 | BarH-like homeobox 1 |
C00000947
|
| 54205 | CYCS, CYC, HCS, THC4 | cytochrome c, somatic |
C00000947
|
| 7913 | DEK, D6S231E | DEK oncogene |
C00000947
|
| 1786 | DNMT1, ADCADN, AIM, CXXC9, DNMT, HSN1E, MCMT | DNA (cytosine-5-)-methyltransferase 1 (EC:2.1.1.37) |
C00000947
|
| 2130 | EWSR1, EWS, bK984G1.4 | EWS RNA-binding protein 1 |
C00000947
|
| 355 | FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6 | Fas cell surface death receptor |
C00000947
|
| 2323 | FLT3LG, FL, FLT3L | fms-related tyrosine kinase 3 ligand |
C00000947
|
| 2495 | FTH1, FHC, FTH, FTHL6, PIG15, PLIF | ferritin, heavy polypeptide 1 (EC:1.16.3.1) |
C00000947
|
| 2896 | GRN, CLN11, GEP, GP88, PCDGF, PEPI, PGRN | granulin |
C00000947
|
| 3014 | H2AFX, H2A.X, H2A/X, H2AX | H2A histone family, member X |
C00000947
|
| 3054 | HCFC1, CFF, HCF-1, HCF1, HFC1, MRX3, VCAF | host cell factor C1 (VP16-accessory protein) |
C00000947
|
| 3162 | HMOX1, HMOX1D, HO-1, HSP32, bK286B10 | heme oxygenase (decycling) 1 (EC:1.14.99.3) |
C00000947
|
| 3232 | HOXD3, HOX1D, HOX4, HOX4A, Hox-4.1 | homeobox D3 |
C00000947
|
| 3329 | HSPD1, CPN60, GROEL, HLD4, HSP-60, HSP60, HSP65, HuCHA60, SPG13 | heat shock 60kDa protein 1 (chaperonin) |
C00000947
|
| 3383 | ICAM1, BB2, CD54, P3.58 | intercellular adhesion molecule 1 |
C00000947
|
| 3586 | IL10, CSIF, GVHDS, IL-10, IL10A, TGIF | interleukin 10 |
C00000947
|
| 2683 | B4GALT1, B4GAL-T1, CDG2D, GGTB2, GT1, GTB, beta4Gal-T1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (EC:2.4.1.22 2.4.1.90 2.4.1.38) |
C00000947
|
| 3559 | IL2RA, CD25, IDDM10, IL2R, TCGFR | interleukin 2 receptor, alpha |
C00000947
|
| 9235 | IL32, IL-32alpha, IL-32beta, IL-32delta, IL-32gamma, NK4, TAIF, TAIFa, TAIFb, TAIFc, TAIFd | interleukin 32 |
C00000947
|
| 3662 | IRF4, LSIRF, MUM1, NF-EM5 | interferon regulatory factor 4 |
C00000947
|
| 3683 | ITGAL, CD11A, LFA-1, LFA1A | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) |
C00000947
|
| 3689 | ITGB2, CD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
C00000947
|
| 4067 | LYN, JTK8, p53Lyn, p56Lyn | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog (EC:2.7.10.2) |
C00000947
|
| 5604 | MAP2K1, CFC3, MAPKK1, MEK1, MKK1, PRKMK1 | mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) |
C00000947
|
| 5605 | MAP2K2, CFC4, MAPKK2, MEK2, MKK2, PRKMK2 | mitogen-activated protein kinase kinase 2 (EC:2.7.12.2) |
C00000947
|
| 472 | ATM, AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1 | ataxia telangiectasia mutated (EC:2.7.11.1) |
C00000947
|
| 468 | ATF4, CREB-2, CREB2, TAXREB67, TXREB | activating transcription factor 4 |
C00000947
|
| 4282 | MIF, GIF, GLIF, MMIF | macrophage migration inhibitory factor (glycosylation-inhibiting factor) (EC:5.3.3.12 5.3.2.1) |
C00000947
|
| 64975 | MRPL41, BMRP, MRP-L27, MRPL27, RPML27 | mitochondrial ribosomal protein L41 |
C00000947
|
| 4493 | MT1E, MT1, MTD | metallothionein 1E |
C00000947
|
| 653361 | NCF1, NCF1A, NOXO2, SH3PXD1A, p47phox | neutrophil cytosolic factor 1 |
C00000947
|
| 4780 | NFE2L2, NRF2 | nuclear factor, erythroid 2-like 2 |
C00000947
|
| 393 | ARHGAP4, C1, RGC1, RhoGAP4, SrGAP4, p115 | Rho GTPase activating protein 4 |
C00000947
|
| 4851 | NOTCH1, TAN1, hN1 | notch 1 |
C00000947
|
| 4869 | NPM1, B23, NPM | nucleophosmin (nucleolar phosphoprotein B23, numatrin) |
C00000947
|
| 5175 | PECAM1, CD31, CD31/EndoCAM, GPIIA', PECA1, PECAM-1, endoCAM | platelet/endothelial cell adhesion molecule 1 |
C00000947
|
| 5187 | PER1, PER, RIGUI, hPER | period circadian clock 1 |
C00000947
|
| 5327 | PLAT, T-PA, TPA | plasminogen activator, tissue (EC:3.4.21.68) |
C00000947
|
| 5328 | PLAU, ATF, BDPLT5, QPD, UPA, URK, u-PA | plasminogen activator, urokinase (EC:3.4.21.73) |
C00000947
|
| 7916 | PRRC2A, BAT2, D6S51, D6S51E, G2 | proline-rich coiled-coil 2A |
C00000947
|
| 302 | ANXA2, ANX2, ANX2L4, CAL1H, LIP2, LPC2, LPC2D, P36, PAP-IV | annexin A2 |
C00000947
|
| 5747 | PTK2, FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK | protein tyrosine kinase 2 (EC:2.7.10.2) |
C00000947
|
| 5879 | RAC1, Rac-1, TC-25, p21-Rac1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) |
C00000947
|
| 5915 | RARB, HAP, NR1B2, RRB2 | retinoic acid receptor, beta |
C00000947
|
| 207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) |
C00000947
|
| 6128 | RPL6, L6, SHUJUN-2, TAXREB107, TXREB1 | ribosomal protein L6 |
C00000947
|
| 6285 | S100B, NEF, S100, S100-B, S100beta | S100 calcium binding protein B |
C00000947
|
| 6286 | S100P, MIG9 | S100 calcium binding protein P |
C00000947
|
| 5054 | SERPINE1, PAI, PAI-1, PAI1, PLANH1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
C00000947
|
| 7536 | SF1, BBP, D11S636, MBBP, ZCCHC25, ZFM1, ZNF162 | splicing factor 1 |
C00000947
|
| 6574 | SLC20A1, GLVR1, Glvr-1, PIT1, PiT-1 | solute carrier family 20 (phosphate transporter), member 1 |
C00000947
|
| 6699 | SPRR1B, CORNIFIN, GADD33, SPRR1 | small proline-rich protein 1B |
C00000947
|
| 79184 | BRCC3, BRCC36, C6.1A, CXorf53 | BRCA1/BRCA2-containing complex, subunit 3 (EC:3.1.2.15) |
C00000947
|
| 6777 | STAT5B, STAT5 | signal transducer and activator of transcription 5B |
C00000947
|
| 6778 | STAT6, D12S1644, IL-4-STAT, STAT6B, STAT6C | signal transducer and activator of transcription 6, interleukin-4 induced |
C00000947
|
| 6817 | SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) |
C00000947
|
| 6932 | TCF7, TCF-1 | transcription factor 7 (T-cell specific, HMG-box) |
C00000947
|
| 7083 | TK1, TK2 | thymidine kinase 1, soluble (EC:2.7.1.21) |
C00000947
|
| 9429 | ABCG2, ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR1, UAQTL1 | ATP-binding cassette, sub-family G (WHITE), member 2 |
C00000947
|
| 943 | TNFRSF8, CD30, D1S166E, Ki-1 | tumor necrosis factor receptor superfamily, member 8 |
C00000947
|
| 7150 | TOP1, TOPI | topoisomerase (DNA) I (EC:5.99.1.2) |
C00000947
|
| 7153 | TOP2A, TOP2, TP2A | topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3) |
C00000947
|
| 2829 | XCR1, CCXCR1, GPR5 | chemokine (C motif) receptor 1 |
C00000947
|
| 51042 | ZNF593, ZT86 | zinc finger protein 593 |
C00000947
|
| 177 | AGER, RAGE | advanced glycosylation end product-specific receptor |
C00005413
|
| 196 | AHR, bHLHe76 | aryl hydrocarbon receptor |
C00005413
|
| 405 | ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2 | aryl hydrocarbon receptor nuclear translocator |
C00005413
|
| 847 | CAT | catalase (EC:1.11.1.6) |
C00005413
|
| 873 | CBR1, CBR, SDR21C1, hCBR1 | carbonyl reductase 1 (EC:1.1.1.189 1.1.1.197 1.1.1.184) |
C00005413
|
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) |
C00005413
|
| 1956 | EGFR, ERBB, ERBB1, HER1, PIG61, mENA | epidermal growth factor receptor (EC:2.7.10.1) |
C00005413
|
| 2936 | GSR | glutathione reductase (EC:1.8.1.7) |
C00005413
|
| 3458 | IFNG, IFG, IFI | interferon, gamma |
C00005413
|
| 3480 | IGF1R, CD221, IGFIR, IGFR, JTK13 | insulin-like growth factor 1 receptor (EC:2.7.10.1) |
C00005413
|
| 3569 | IL6, BSF2, HGF, HSF, IFNB2, IL-6 | interleukin 6 (interferon, beta 2) |
C00005413
|
| 3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00005413
|
| 3667 | IRS1, HIRS-1 | insulin receptor substrate 1 |
C00005413
|
| 3725 | JUN, AP-1, AP1, c-Jun | jun proto-oncogene |
C00005413
|
| 7039 | TGFA, TFGA | transforming growth factor, alpha |
C00005413
|
| 7422 | VEGFA, MVCD1, VEGF, VPF | vascular endothelial growth factor A |
C00005413
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (114)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
| #203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
| #606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #600807 | Asthma, susceptibility to |
Q13093
|
| #608584 | Asthma-related traits, susceptibility to, 2 |
Q6W5P4
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #613985 | Beta-thalassemia |
P68871
|
| #603902 | Beta-thalassemia, dominant inclusion body type |
P68871
|
| #601816 | Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 |
P22309
|
| #614490 | Blood group, junior system; jr |
Q9UNQ0
|
| #210900 | Bloom syndrome; blm |
P54132
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #603513 | Cerebral palsy, spastic quadriplegic, 1; cpsq1 |
Q99259
|
| #118300 | Charcot-marie-tooth disease and deafness |
Q01453
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #118220 | Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a |
Q01453
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #602579 | Congenital disorder of glycosylation, type ib; cdg1b |
P34949
|
| #218800 | Crigler-najjar syndrome, type i |
P22309
P22310 |
| #606785 | Crigler-najjar syndrome, type ii |
P22309
P22310 |
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #133239 | Esophageal cancer |
P04637
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #301500 | Fabry disease |
P06280
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #608013 | Gaucher disease, perinatal lethal |
P04062
|
| #230800 | Gaucher disease, type i |
P04062
|
| #230900 | Gaucher disease, type ii |
P04062
|
| #231000 | Gaucher disease, type iii |
P04062
|
| #231005 | Gaucher disease, type iiic |
P04062
|
| #143500 | Gilbert syndrome |
P22309
P22310 |
| #232300 | Glycogen storage disease ii |
P10253
|
| #139393 | Guillain-barre syndrome, familial; gbs |
Q01453
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #140700 | Heinz body anemias |
P68871
|
| #114550 | Hepatocellular carcinoma |
P08581
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #237900 | Hyperbilirubinemia, transient familial neonatal; hblrtfn |
P22309
|
| #143860 | Hyperchlorhidrosis, isolated |
O43570
|
| #149400 | Hyperekplexia, hereditary 1; hkpx1 |
P23415
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #145900 | Hypertrophic neuropathy of dejerine-sottas |
Q01453
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #146300 | Hypophosphatasia, adult |
P05186
|
| #241510 | Hypophosphatasia, childhood |
P05186
|
| #241500 | Hypophosphatasia, infantile |
P05186
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #147050 | Ige responsiveness, atopic; iger |
Q13093
|
| #601626 | Leukemia, acute myeloid; aml |
P36888
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #211980 | Lung cancer |
P04637
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #613839 | Megaloblastic anemia due to dihydrofolate reductase deficiency |
P00374
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #162500 | Neuropathy, hereditary, with liability to pressure palsies; hnpp |
Q01453
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #168600 | Parkinson disease, late-onset; pd |
P04062
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #614674 | Periodic fever, menstrual cycle-dependent |
P08908
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #614278 | Platelet-activating factor acetylhydrolase deficiency; pafad |
Q13093
|
| #614390 | Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 |
P00734
|
| #613679 | Prothrombin deficiency, congenital |
P00734
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #265800 | Pycnodysostosis |
P43235
|
| #605074 | Renal cell carcinoma, papillary, 1; rccp1 |
P08581
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #600852 | Retinitis pigmentosa 17; rp17 |
P22748
|
| #603903 | Sickle cell anemia |
P68871
|
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #605361 | Spinocerebellar ataxia 14; sca14 |
P05129
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| #601367 | Stroke, ischemic |
P00734
P24723 |
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #188050 | Thrombophilia due to thrombin defect; thph1 |
P00734
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #138900 | Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 |
Q9UNQ0
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #278300 | Xanthinuria, type i |
P47989
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
| #112100 | Yt blood group antigen |
P22303
|
KEGG DISEASE (108)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H01302 | Hyperchlorhidrosis isolated (HCHLH) |
O43570
(related)
|
| H00021 | Renal cell carcinoma |
O43570
(marker)
P04637 (marker) P08581 (related) Q16790 (marker) |
| H01197 | Dihydrofolate reductase (DHFR) deficiency |
P00374
(related)
|
| H00223 | Inherited thrombophilia |
P00734
(related)
|
| H01254 | Congenital prothrombin deficiency |
P00734
(related)
|
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
Q01453 (related) |
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04637 (related) |
| H00066 | Lewy body dementia (LBD) |
P04062
(related)
|
| H00126 | Gaucher disease |
P04062
(related)
|
| H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
| H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
Q01196 (related) |
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
P10415 (related) P28907 (marker) |
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
P10415 (related) |
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00016 | Oral cancer |
P04637
(related)
P04637 (marker) |
| H00017 | Esophageal cancer |
P04637
(related)
P04637 (marker) P35354 (related) |
| H00018 | Gastric cancer |
P04637
(related)
P08581 (related) P10415 (related) |
| H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) P68871 (marker) |
| H00022 | Bladder cancer |
P04637
(related)
P68871 (marker) |
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) P35354 (related) |
| H00027 | Ovarian cancer |
P04637
(related)
|
| H00028 | Choriocarcinoma |
P04637
(related)
P10415 (related) |
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00031 | Breast cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
P27487 (marker) |
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
P14679 (marker) |
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
P10415 (related) |
| H00042 | Glioma |
P04637
(related)
P04637 (marker) |
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00046 | Cholangiocarcinoma |
P04637
(related)
P08581 (related) P35354 (related) |
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00055 | Laryngeal cancer |
P04637
(related)
P04637 (marker) |
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
P05129
(related)
Q9NUW8 (related) |
| H00213 | Hypophosphatasia |
P05186
(related)
|
| H00125 | Fabry disease |
P06280
(related)
|
| H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
| H00030 | Cervical cancer |
P10415
(related)
|
| H00054 | Nasopharyngeal cancer |
P10415
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00023 | Testicular cancer |
P10696
(marker)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00208 | Hyperbilirubinemia |
P22309
(related)
|
| H00527 | Retinitis pigmentosa (RP) |
P22748
(related)
|
| H00769 | Hyperekplexia |
P23415
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00118 | Congenital disorders of glycosylation (CDG) type I |
P34949
(related)
|
| H00003 | Acute myeloid leukemia (AML) |
P36888
(related)
Q01196 (related) Q01196 (marker) Q13951 (marker) |
| H00273 | Pycnodysostosis |
P43235
(related)
|
| H00425 | Lysosomal cysteine protease deficiencies |
P43235
(related)
|
| H00192 | Xanthinuria |
P47989
(related)
|
| H00094 | DNA repair defects |
P54132
(related)
|
| H00296 | Defects in RecQ helicases |
P54132
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00228 | Thalassemia |
P68871
(related)
|
| H00229 | Sickle cell anemia (SCA) |
P68871
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H01296 | Hereditary neuropathy with liability to pressure palsies (HNPP) |
Q01453
(related)
|
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00408 | Type I diabetes mellitus |
Q04759
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H01097 | Cerebral palsy |
Q99259
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|
Diseases related to CTD interactions
27 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D001930 | Brain Injuries |
C00000601
|
| D002375 | Catalepsy |
C00000601
|
| D018476 | Hypokinesia |
C00000601
|
| D020244 | Infarction, Middle Cerebral Artery |
C00000601
|
| D020734 | Parkinsonian Disorders |
C00000601
|
| D009410 | Nerve Degeneration |
C00011512
|
| D050197 | Atherosclerosis |
C00000947
|
| D001943 | Breast Neoplasms |
C00000947
|
| D002471 | Cell Transformation, Neoplastic |
C00000947
|
| D003556 | Cystitis |
C00000947
|
| D056486 | Drug-Induced Liver Injury |
C00000947
|
| D034381 | Hearing Loss |
C00000947
|
| D006331 | Heart Diseases |
C00000947
|
| D020138 | HYPERHOMOCYSTEINEMIA |
C00000947
|
| D008107 | Liver Diseases |
C00000947
|
| D017114 | Liver Failure, Acute |
C00000947
|
| D008113 | Liver Neoplasms |
C00000947
|
| D008325 | Mammary Neoplasms, Experimental |
C00000947
|
| D009362 | Neoplasm Metastasis |
C00000947
|
| D001424 | Bacterial Infections |
C00005413
|
| D003092 | Colitis |
C00005413
|
| D004409 | Dyskinesia, Drug-Induced |
C00005413
|
| D015212 | Inflammatory Bowel Diseases |
C00005413
|
| D007674 | Kidney Diseases |
C00005413
|
| D028361 | Mitochondrial Diseases |
C00005413
|
| D010243 | Paralysis |
C00005413
|
| D013276 | Stomach Ulcer |
C00005413
|