Gymnadenia conopsea R.BR.
Species
KNApSAcK Entry
| Organism name | Gymnadenia conopsea R.BR. |
|---|---|
| Genus | Gymnadenia |
| Family | Orchidaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Gymnadenia |
|---|---|
| Linked NCBI taxonomy ID | 59323 |
| Linked level | genus |
Family
| Family in NCBI taxonomy | Orchidaceae |
|---|---|
| ID | 4747 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | Liliopsida |
|---|---|
| ID | 4447 |
Metabolite list (37)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00000587
|
(-)-Pinoresinol
|
CHEMBL267963
CHEMBL487611 CHEMBL460862 |
7 / 5 / 6 | No. 38 | No. 21 |
|
||
|
C00030988
|
Phenyl beta-D-glucopyranoside
|
CHEMBL1172858
|
C033857
|
No. 45 | No. 72 |
|
||
|
C00029539
|
4-Methylphenyl beta-D-glucopyranoside
|
CHEMBL1172859
|
No. 45 | No. 72 |
|
|||
|
C00029812
|
Benzyl beta-D-glucopyranoside
/ (-)-Benzyl-O-beta-D-glucopyranoside |
CHEMBL1170453
CHEMBL2336738 |
C410942
|
No. 45 | No. 72 |
|
||
|
C00029538
|
Methylarbutin
/ 4-Methoxyphenyl beta-D-glucopyranoside |
CHEMBL1173000
CHEMBL1969163 |
C031919
|
No. 45 | No. 72 |
|
||
|
C00029534
|
4-Hydroxybenzyl beta-D-glucopyranoside
|
No. 45 | No. 72 |
|
||||
|
C00030438
|
Gymconopin A
|
No. 313 |
|
|||||
|
C00030439
|
Gymconopin B
|
No. 313 |
|
|||||
|
C00030441
|
Gymconopin D
|
No. 313 |
|
|||||
|
C00015251
|
1-(4-Hydroxybenzyl)-4-methoxy-9,10-dihydrophenanthrene-2,7-diol
/ 2,7-Dihydroxy-1-(4-hydroxybenzyl)-4-methoxy-9,10-dihydrophenanthrene |
No. 313 |
|
|||||
|
C00029863
|
Bulbocol
|
No. 313 |
|
|||||
|
C00015532
|
Flavanthrin
/ Blestriarene A / 4,4'-Dimethoxy-2,2',7,7'-tetrahydroxy-9,9',10,10'-tetrahydro-[1,1'-biphenanthrene] |
CHEMBL564527
|
No. 602 | No. 30 |
|
|||
|
C00030440
|
Gymconopin C
|
No. 602 | No. 30 |
|
||||
|
C00002872
|
Blestriarene B
|
CHEMBL369741
|
No. 602 | No. 30 |
|
|||
|
C00015531
|
Blestriarene C
/ (-)-Blestriarene C / Cirrhopetalanthrin / 4,4'-Dimethoxy-2,2',7,7'-tetrahydroxy-[1,1'-biphenanthrene] |
CHEMBL359501
|
No. 602 | No. 30 |
|
|||
|
C00029862
|
Bulbocodin D
|
No. 744 |
|
|||||
|
C00029861
|
Bulbocodin C
|
No. 744 |
|
|||||
|
C00000856
|
4-Hydroxybenzoic acid
/ p-Hydroxybenzoic acid |
CHEMBL441343
|
C038193
|
21 / 7 / 16 | 2 / 1 | No. 817 | No. 81 |
|
|
C00007558
|
Syringaldehyde
/ 4-Hydroxy-3,5-dimethoxybenzaldehyde |
CHEMBL225303
|
C069665
|
No. 856 |
|
|||
|
C00032269
|
Syringol
|
CHEMBL109652
|
C010120
|
3 / 5 / 2 | No. 856 |
|
||
|
C00000152
|
p-Coumaric acid
|
CHEMBL66879
CHEMBL2336752 |
C032171
|
23 / 13 / 18 | 6 / 1 | No. 904 | No. 6 |
|
|
C00029533
|
Gastrodigenin
/ 4-Methylolphenol / p-Hydroxybenzyl alcohol / 4-Hydroxybenzyl alcohol |
CHEMBL202132
|
C018966
|
6 / 3 / 4 | 0 / 2 | No. 936 | No. 6 |
|
|
C00002682
|
Vanillic acid
/ 3-Methoxy-4-hydroxybenzoic acid |
CHEMBL120568
|
D014641
|
5 / 3 / 3 | 5 / 0 | No. 1073 |
|
|
|
C00002743
|
Ferulic acid
/ 3-(4-Hydroxy-3-methoxyphenyl)-2-propenoic acid |
CHEMBL32749
|
C004999
|
110 / 52 / 40 | 16 / 6 | No. 1366 | No. 6 |
|
|
C00002644
|
Catechol
/ Pyrocatechol |
CHEMBL280998
|
C034221
|
148 / 82 / 64 | 22 / 5 | No. 1590 | No. 82 |
|
|
C00030443
|
Gymnoside VIII
|
No. 1768 |
|
|||||
|
C00030444
|
Gymnoside X
|
No. 1768 |
|
|||||
|
C00030082
|
Dactylorhin A
|
No. 1768 |
|
|||||
|
C00030442
|
Gymnoside IX
|
No. 1768 |
|
|||||
|
C00030083
|
Dactylorhin B
/ (-)-Dactylorhin B |
No. 1768 |
|
|||||
|
C00029435
|
2,4-Dihydroxybenzaldehyde
|
CHEMBL243587
|
2 / 0 / 0 | No. 2076 |
|
|||
|
C00002657
|
p-Formylphenol
/ 4-Hydroxybenzaldehyde / p-Hydroxybenzaldehyde |
CHEMBL14193
|
C011483
|
3 / 2 / 2 | No. 2076 |
|
||
|
C00030690
|
Loroglossin
|
No. 2281 |
|
|||||
|
C00030085
|
Dactylose B
|
No. 4401 |
|
|||||
|
C00030084
|
Dactylose A
|
No. 4401 |
|
|||||
|
C00019698
|
Thymidine
/ Deoxythymidine |
CHEMBL6497
CHEMBL42372 CHEMBL52609 CHEMBL211174 CHEMBL374731 CHEMBL2067985 |
D013936
|
6 / 4 / 3 | 16 / 16 | No. 4547 |
|
|
|
C00029547
|
5-Hydroxymethylfuraldehyde
/ 5-Hydroxymethyl-2-furfural / 5-Hydroxymethyl-2-furaldehyde / 5-(Hydroxymethyl)-2-furaldehyde |
CHEMBL185885
|
C008046
|
4 / 3 / 3 | 2 / 5 | No. 6025 |
|
Human Protein / Gene in interactions
190 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P22748 | Carbonic anhydrase 4 | Lyase | C00000152 C00000856 C00002644 C00002743 | 1 / 1 |
| Q9Y2D0 | Carbonic anhydrase 5B, mitochondrial | Lyase | C00000152 C00000856 C00002644 C00002743 | 0 / 0 |
| P35218 | Carbonic anhydrase 5A, mitochondrial | Lyase | C00000152 C00000856 C00002644 C00002743 | 0 / 0 |
| P00915 | Carbonic anhydrase 1 | Lyase | C00000152 C00000856 C00002644 C00002743 | 0 / 0 |
| Q16790 | Carbonic anhydrase 9 | Lyase | C00000152 C00000856 C00002644 C00002743 | 0 / 1 |
| P03372 | Estrogen receptor | NR3A1 | C00000152 C00002644 C00002682 C00002743 | 1 / 1 |
| P07451 | Carbonic anhydrase 3 | Lyase | C00000152 C00000856 C00002644 C00002743 | 0 / 0 |
| O43570 | Carbonic anhydrase 12 | Lyase | C00000152 C00000856 C00002644 C00002743 | 1 / 2 |
| Q9ULX7 | Carbonic anhydrase 14 | Lyase | C00000152 C00000856 C00002644 C00002743 | 0 / 0 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00000152 C00000856 C00002644 C00002743 | 1 / 2 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00000152 C00000856 C00002644 C00002743 | 1 / 8 |
| P43166 | Carbonic anhydrase 7 | Lyase | C00000152 C00000856 C00002644 C00002743 | 0 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00000152 C00000587 C00002644 C00002743 | 0 / 3 |
| P23280 | Carbonic anhydrase 6 | Lyase | C00000152 C00000856 C00002644 C00002743 | 0 / 0 |
| P51649 | Succinate-semialdehyde dehydrogenase, mitochondrial | Oxidoreductase | C00000856 C00002657 C00029533 | 1 / 1 |
| P06241 | Tyrosine-protein kinase Fyn | Src | C00002644 C00002743 C00029533 | 0 / 0 |
| P80404 | 4-aminobutyrate aminotransferase, mitochondrial | Transferase | C00000856 C00002657 C00029533 | 1 / 1 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00002644 C00002743 C00029547 | 0 / 1 |
| P30988 | Calcitonin receptor | Calcitonin receptor | C00002644 C00002743 | 0 / 0 |
| P49146 | Neuropeptide Y receptor type 2 | Neuropeptide Y receptor | C00002644 C00002743 | 0 / 0 |
| Q16539 | Mitogen-activated protein kinase 14 | p38 | C00002644 C00002743 | 0 / 0 |
| Q13093 | Platelet-activating factor acetylhydrolase | Enzyme | C00000152 C00002743 | 3 / 0 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00002644 C00002743 | 0 / 0 |
| P23975 | Sodium-dependent noradrenaline transporter | Norepinephrine | C00002644 C00002743 | 1 / 1 |
| P29466 | Caspase-1 | C14 | C00002644 C00002743 | 0 / 0 |
| P17252 | Protein kinase C alpha type | Alpha | C00002644 C00002743 | 0 / 0 |
| P27361 | Mitogen-activated protein kinase 3 | Erk | C00002644 C00002743 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00002644 C00019698 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00002644 C00002682 | 0 / 0 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00002644 C00002743 | 2 / 2 |
| P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | C00002644 C00002743 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00002644 C00002743 | 0 / 1 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00002644 C00002743 | 1 / 1 |
| P51580 | Thiopurine S-methyltransferase | Enzyme | C00000856 C00002682 | 1 / 1 |
| P33032 | Melanocortin receptor 5 | Melanocortin receptor | C00002644 C00002743 | 0 / 0 |
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00002644 C00002743 | 1 / 1 |
| P25105 | Platelet-activating factor receptor | PAF receptor | C00002644 C00002743 | 0 / 0 |
| P08246 | Neutrophil elastase | S1A | C00002644 C00002743 | 2 / 1 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00002644 C00002743 | 2 / 2 |
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | C00002644 C00002743 | 0 / 1 |
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00002644 C00002743 | 1 / 1 |
| P25021 | Histamine H2 receptor | Histamine receptor | C00002644 C00002743 | 0 / 0 |
| P35367 | Histamine H1 receptor | Histamine receptor | C00002644 C00002743 | 0 / 0 |
| Q01959 | Sodium-dependent dopamine transporter | Dopamine | C00002644 C00002743 | 1 / 0 |
| P08912 | Muscarinic acetylcholine receptor M5 | Acetylcholine receptor | C00002644 C00002743 | 0 / 0 |
| P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | C00002644 C00002743 | 0 / 0 |
| P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | C00002644 C00002743 | 0 / 0 |
| P25103 | Substance-P receptor | Neurokinin receptor | C00002644 C00002743 | 0 / 0 |
| P08173 | Muscarinic acetylcholine receptor M4 | Acetylcholine receptor | C00002644 C00002743 | 0 / 0 |
| P25024 | C-X-C chemokine receptor type 1 | CXC chemokine receptor | C00002644 C00002743 | 0 / 0 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00002644 C00002743 | 0 / 0 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00002644 C00002743 | 0 / 0 |
| Q08209 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Ser_Thr | C00002644 C00002743 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00002644 C00002743 | 0 / 1 |
| P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | C00002644 C00002743 | 0 / 0 |
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00002644 C00002743 | 0 / 0 |
| P22303 | Acetylcholinesterase | Hydrolase | C00002644 C00002743 | 1 / 0 |
| P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00000587 C00002644 | 0 / 0 |
| P14416 | D(2) dopamine receptor | Dopamine receptor | C00002644 C00002743 | 2 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00002644 C00002743 | 0 / 0 |
| P37288 | Vasopressin V1a receptor | Vasopressin and oxytocin receptor | C00002644 C00002743 | 0 / 0 |
| P41145 | Kappa-type opioid receptor | Opioid receptor | C00002644 C00002743 | 0 / 0 |
| Q9Y271 | Cysteinyl leukotriene receptor 1 | Leukotriene receptor | C00002644 C00002743 | 0 / 0 |
| P29274 | Adenosine receptor A2a | Adenosine receptor | C00002644 C00002743 | 0 / 0 |
| P30542 | Adenosine receptor A1 | Adenosine receptor | C00002644 C00002743 | 0 / 0 |
| P25929 | Neuropeptide Y receptor type 1 | Neuropeptide Y receptor | C00002644 C00002743 | 0 / 0 |
| P50052 | Type-2 angiotensin II receptor | Angiotensin receptor | C00002644 C00002743 | 1 / 1 |
| P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | C00002644 C00002743 | 1 / 0 |
| P17948 | Vascular endothelial growth factor receptor 1 | Vegfr | C00002644 C00002743 | 0 / 0 |
| P41968 | Melanocortin receptor 3 | Melanocortin receptor | C00002644 C00002743 | 1 / 0 |
| P18089 | Alpha-2B adrenergic receptor | Adrenergic receptor | C00002644 C00002743 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00002644 C00029547 | 0 / 0 |
| P24557 | Thromboxane-A synthase | Cytochrome P450 5A1 | C00002644 C00002743 | 1 / 1 |
| P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | C00002644 C00002743 | 0 / 0 |
| P06239 | Tyrosine-protein kinase Lck | Src | C00002644 C00002743 | 0 / 1 |
| O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | C00002644 C00002743 | 0 / 0 |
| Q8TDS4 | Hydroxycarboxylic acid receptor 2 | Hydroxycarboxylic acid receptor | C00000152 C00002743 | 0 / 0 |
| P51449 | Nuclear receptor ROR-gamma | Nuclear hormone receptor subfamily 1 group F member 3 | C00002644 C00029547 | 0 / 0 |
| P25025 | C-X-C chemokine receptor type 2 | CXC chemokine receptor | C00002644 C00002743 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00002644 C00002743 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00002644 C00002743 | 0 / 0 |
| P08575 | Receptor-type tyrosine-protein phosphatase C | Enzyme | C00002644 C00002743 | 2 / 1 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00002644 C00002743 | 0 / 0 |
| P41597 | C-C chemokine receptor type 2 | CC chemokine receptor | C00002644 C00002743 | 1 / 0 |
| P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | C00002644 C00002743 | 0 / 0 |
| P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | C00002644 C00002743 | 0 / 0 |
| P21917 | D(4) dopamine receptor | Dopamine receptor | C00002644 C00002743 | 0 / 0 |
| P25100 | Alpha-1D adrenergic receptor | Adrenergic receptor | C00002644 C00002743 | 0 / 0 |
| P35462 | D(3) dopamine receptor | Dopamine receptor | C00002644 C00002743 | 1 / 0 |
| P41143 | Delta-type opioid receptor | Opioid receptor | C00002644 C00002743 | 0 / 0 |
| Q92731 | Estrogen receptor beta | NR3A2 | C00002644 C00002743 | 0 / 1 |
| P41595 | 5-hydroxytryptamine receptor 2B | Serotonin receptor | C00002644 C00002743 | 0 / 0 |
| P15121 | Aldose reductase | Enzyme | C00000152 C00002682 | 0 / 0 |
| P25101 | Endothelin-1 receptor | Endothelin receptor | C00002644 C00002743 | 0 / 0 |
| P30411 | B2 bradykinin receptor | Bradykinin receptor | C00002644 C00002743 | 0 / 0 |
| P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | C00002644 C00002743 | 0 / 0 |
| P32245 | Melanocortin receptor 4 | Melanocortin receptor | C00002644 C00002743 | 1 / 0 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00002644 C00002743 | 1 / 0 |
| P32238 | Cholecystokinin receptor type A | Cholecystokinin receptor | C00002644 C00002743 | 0 / 0 |
| P08311 | Cathepsin G | S1A | C00002644 C00002743 | 0 / 0 |
| Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | C00002644 C00002743 | 1 / 0 |
| P51681 | C-C chemokine receptor type 5 | CC chemokine receptor | C00002644 C00002743 | 3 / 0 |
| P03956 | Interstitial collagenase | M10A | C00002644 C00002743 | 0 / 1 |
| P32241 | Vasoactive intestinal polypeptide receptor 1 | Vasoactive intestinal peptide receptor | C00002644 C00002743 | 0 / 0 |
| P51679 | C-C chemokine receptor type 4 | CC chemokine receptor | C00002644 C00002743 | 0 / 0 |
| P21452 | Substance-K receptor | Neurokinin receptor | C00002644 C00002743 | 0 / 0 |
| P20309 | Muscarinic acetylcholine receptor M3 | Acetylcholine receptor | C00002644 C00002743 | 1 / 0 |
| P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | C00002644 C00002743 | 5 / 9 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00002644 C00002743 | 0 / 0 |
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00000587 C00002644 | 5 / 3 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00002644 C00029435 | 0 / 0 |
| P08172 | Muscarinic acetylcholine receptor M2 | Acetylcholine receptor | C00002644 C00002743 | 2 / 0 |
| P11229 | Muscarinic acetylcholine receptor M1 | Acetylcholine receptor | C00002644 C00002743 | 0 / 0 |
| P14679 | Tyrosinase | Oxidoreductase | C00000152 C00002743 | 4 / 2 |
| P21554 | Cannabinoid receptor 1 | Cannabinoid receptor | C00002644 C00002743 | 0 / 0 |
| P31645 | Sodium-dependent serotonin transporter | Serotonin | C00002644 C00002743 | 2 / 0 |
| P10145 | Interleukin-8 | Secreted protein | C00002644 | 0 / 0 |
| Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | Enzyme | C00002644 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00002644 | 0 / 0 |
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00002644 | 0 / 0 |
| P46108 | Adapter molecule crk | Unclassified protein | C00029533 | 0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00002644 | 1 / 1 |
| O00519 | Fatty-acid amide hydrolase 1 | Enzyme | C00029435 | 0 / 0 |
| P11021 | 78 kDa glucose-regulated protein | Unclassified protein | C00002644 | 0 / 0 |
| Q96RI1 | Bile acid receptor | NR1H4 | C00002644 | 0 / 0 |
| P54855 | UDP-glucuronosyltransferase 2B15 | Enzyme | C00002743 | 0 / 0 |
| O60656 | UDP-glucuronosyltransferase 1-9 | Enzyme | C00000856 | 0 / 0 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00002644 | 0 / 0 |
| P62993 | Growth factor receptor-bound protein 2 | Other cytosolic protein | C00029533 | 0 / 0 |
| P42858 | Huntingtin | Unclassified protein | C00002682 | 1 / 1 |
| P39748 | Flap endonuclease 1 | Enzyme | C00002644 | 0 / 0 |
| P08253 | 72 kDa type IV collagenase | M10A | C00002644 | 1 / 3 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00002644 | 3 / 3 |
| Q04828 | Aldo-keto reductase family 1 member C1 | Enzyme | C00000152 | 0 / 0 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00002644 | 2 / 2 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00002644 | 1 / 1 |
| Q01453 | Peripheral myelin protein 22 | Unclassified protein | C00002644 | 5 / 2 |
| P14902 | Indoleamine 2,3-dioxygenase 1 | Enzyme | C00002657 | 0 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00000587 | 0 / 0 |
| Q9HAW9 | UDP-glucuronosyltransferase 1-8 | Enzyme | C00000856 | 0 / 0 |
| P42330 | Aldo-keto reductase family 1 member C3 | Enzyme | C00000152 | 0 / 0 |
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00002644 | 0 / 0 |
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00002644 | 0 / 0 |
| Q9HAW7 | UDP-glucuronosyltransferase 1-7 | Enzyme | C00000856 | 0 / 0 |
| P54132 | Bloom syndrome protein | Enzyme | C00002644 | 1 / 2 |
| Q9GZT9 | Egl nine homolog 1 | Enzyme | C00002644 | 1 / 1 |
| Q9UQ49 | Sialidase-3 | Enzyme | C00000856 | 0 / 0 |
| P34969 | 5-hydroxytryptamine receptor 7 | Serotonin receptor | C00002743 | 0 / 0 |
| P04183 | Thymidine kinase, cytosolic | Enzyme | C00019698 | 0 / 1 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00019698 | 3 / 1 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00029547 | 3 / 2 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00002644 | 0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00002644 | 0 / 0 |
| P00519 | Tyrosine-protein kinase ABL1 | Abl | C00029533 | 1 / 2 |
| P02545 | Prelamin-A/C | Unclassified protein | C00002644 | 11 / 10 |
| O15245 | Solute carrier family 22 member 1 | Drug uniporter | C00019698 | 0 / 0 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00002644 | 0 / 0 |
| P23919 | Thymidylate kinase | Enzyme | C00019698 | 0 / 0 |
| P52895 | Aldo-keto reductase family 1 member C2 | Enzyme | C00000152 | 1 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00002644 | 0 / 0 |
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00000587 | 0 / 0 |
| P22309 | UDP-glucuronosyltransferase 1-1 | Enzyme | C00002743 | 5 / 1 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00002644 | 4 / 3 |
| Q99549 | M-phase phosphoprotein 8 | Unclassified protein | C00002644 | 0 / 0 |
| P19224 | UDP-glucuronosyltransferase 1-6 | Enzyme | C00000856 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00002644 | 0 / 0 |
| P22894 | Neutrophil collagenase | M10A | C00002644 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00002644 | 0 / 0 |
| O60218 | Aldo-keto reductase family 1 member B10 | Enzyme | C00000152 | 0 / 0 |
| Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00000587 | 0 / 0 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00002644 | 2 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00002644 | 1 / 1 |
| Q9HAW8 | UDP-glucuronosyltransferase 1-10 | Enzyme | C00000856 | 0 / 0 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00002644 | 4 / 1 |
| P17516 | Aldo-keto reductase family 1 member C4 | Enzyme | C00000152 | 1 / 0 |
| P08254 | Stromelysin-1 | M10A | C00002644 | 1 / 0 |
| P22310 | UDP-glucuronosyltransferase 1-4 | Enzyme | C00002743 | 3 / 0 |
| Q12794 | Hyaluronidase-1 | Enzyme | C00002743 | 1 / 2 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00002644 | 0 / 0 |
| P19971 | Thymidine phosphorylase | Enzyme | C00019698 | 1 / 1 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00002644 | 0 / 0 |
| P40225 | Thrombopoietin | Unclassified protein | C00002644 | 1 / 1 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00002644 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00002644 | 1 / 1 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00002644 | 1 / 0 |
| P18507 | Gamma-aminobutyric acid receptor subunit gamma-2 | GABA-A gamma | C00032269 | 4 / 2 |
| P47870 | Gamma-aminobutyric acid receptor subunit beta-2 | GABA-A beta | C00032269 | 0 / 0 |
| P14867 | Gamma-aminobutyric acid receptor subunit alpha-1 | GABA-A alpha | C00032269 | 1 / 1 |
| P42345 | Serine/threonine-protein kinase mTOR | Enzyme | C00002644 | 0 / 0 |
| Q9H0H5 | Rac GTPase-activating protein 1 | Unclassified protein | C00000587 | 0 / 0 |
53 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 6817 | SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) |
C00000152
C00000856
C00002644
C00029547
|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00000152
C00002743
|
| 3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00002644
C00019698
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00002644
C00019698
|
| 1544 | CYP1A2, CP12, P3-450, P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) |
C00000152
C00002743
|
| 4846 | NOS3, ECNOS, eNOS | nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) |
C00000152
C00002682
|
| 6799 | SULT1A2, HAST4, P-PST, ST1A2, STP2, TSPST2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 (EC:2.8.2.1) |
C00002644
C00029547
|
| 4609 | MYC, MRTL, MYCC, bHLHe39, c-Myc | v-myc avian myelocytomatosis viral oncogene homolog |
C00002644
C00019698
|
| 5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00000152
C00002743
|
| 54576 | UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H | UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) |
C00002682
C00002743
|
| 54577 | UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G | UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) |
C00002682
C00002743
|
| 7299 | TYR, ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3 | tyrosinase (EC:1.14.18.1) |
C00000152
C00002743
|
| 54575 | UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J | UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) |
C00002682
C00002743
|
| 54659 | UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C | UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) |
C00002682
C00002743
|
| 6352 | CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP | chemokine (C-C motif) ligand 5 |
C00002644
|
| 5925 | RB1, OSRC, RB, p105-Rb, pRb, pp110 | retinoblastoma 1 |
C00002743
|
| 5742 | PTGS1, COX1, COX3, PCOX1, PES-1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00002743
|
| 5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00002743
|
| 5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00002743
|
| 212 | ALAS2, ALAS-E, ALASE, ANH1, ASB, XLDPP, XLEPP, XLSA | aminolevulinate, delta-, synthase 2 (EC:2.3.1.37) |
C00002644
|
| 23621 | BACE1, ASP2, BACE, HSPC104 | beta-site APP-cleaving enzyme 1 (EC:3.4.23.46) |
C00002743
|
| 840 | CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 | caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) |
C00002644
|
| 6356 | CCL11, SCYA11 | chemokine (C-C motif) ligand 11 |
C00002644
|
| 6347 | CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF | chemokine (C-C motif) ligand 2 |
C00002644
|
| 6348 | CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3 | chemokine (C-C motif) ligand 3 |
C00002644
|
| 6351 | CCL4, ACT2, AT744.1, G-26, HC21, LAG-1, LAG1, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4 | chemokine (C-C motif) ligand 4 |
C00002644
|
| 6319 | SCD, FADS5, MSTP008, SCD1, SCDOS | stearoyl-CoA desaturase (delta-9-desaturase) (EC:1.14.19.1) |
C00002743
|
| 1312 | COMT | catechol-O-methyltransferase (EC:2.1.1.6) |
C00002644
|
| 1571 | CYP2E1, CPE1, CYP2E, P450-J, P450C2E | cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) |
C00002644
|
| 2623 | GATA1, ERYF1, GATA-1, GF-1, GF1, NF-E1, NFE1, XLANP, XLTDA, XLTT | GATA binding protein 1 (globin transcription factor 1) |
C00002644
|
| 3043 | HBB, CD113t-C, beta-globin | hemoglobin, beta |
C00002644
|
| 3145 | HMBS, PBG-D, PBGD, PORC, UPS | hydroxymethylbilane synthase (EC:2.5.1.61) |
C00002644
|
| 3586 | IL10, CSIF, GVHDS, IL-10, IL10A, TGIF | interleukin 10 |
C00002644
|
| 1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
C00002743
|
| 595 | CCND1, BCL1, D11S287E, PRAD1, U21B31 | cyclin D1 |
C00002743
|
| 1728 | NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1 | NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) |
C00002644
|
| 6818 | SULT1A3, HAST, HAST3, M-PST, ST1A3/ST1A4, ST1A5, STM, TL-PST | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 (EC:2.8.2.1) |
C00002644
|
| 6819 | SULT1C2, ST1C1, ST1C2, SULT1C1, humSULTC2 | sulfotransferase family, cytosolic, 1C, member 2 (EC:2.8.2.-) |
C00002644
|
| 7037 | TFRC, CD71, T9, TFR, TFR1, TR, TRFR, p90 | transferrin receptor |
C00002644
|
| 3952 | LEP, LEPD, OB, OBS | leptin |
C00000856
|
| 248 | ALPI, IAP | alkaline phosphatase, intestinal (EC:3.1.3.1) |
C00019698
|
| 581 | BAX, BCL2L4 | BCL2-associated X protein |
C00019698
|
| 842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00019698
|
| 1435 | CSF1, CSF-1, MCSF | colony stimulating factor 1 (macrophage) (EC:2.7.10.1) |
C00019698
|
| 1906 | EDN1, ET1, HDLCQ7, PPET1 | endothelin 1 |
C00019698
|
| 356 | FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6 | Fas ligand (TNF superfamily, member 6) |
C00019698
|
| 3091 | HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
C00019698
|
| 3162 | HMOX1, HMOX1D, HO-1, HSP32, bK286B10 | heme oxygenase (decycling) 1 (EC:1.14.99.3) |
C00019698
|
| 3479 | IGF1, IGF-I, IGF1A, IGFI | insulin-like growth factor 1 (somatomedin C) |
C00019698
|
| 4312 | MMP1, CLG, CLGN | matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7) |
C00019698
|
| 4548 | MTR, HMAG, MS, cblG | 5-methyltetrahydrofolate-homocysteine methyltransferase (EC:2.1.1.13) |
C00019698
|
| 9154 | SLC28A1, CNT1, HCNT1 | solute carrier family 28 (concentrative nucleoside transporter), member 1 |
C00019698
|
| 1890 | TYMP, ECGF, ECGF1, MEDPS1, MNGIE, MTDPS1, PDECGF, TP, hPD-ECGF | thymidine phosphorylase (EC:2.4.2.4) |
C00019698
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (113)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #614279 | 46,xy sex reversal 8; srxy8 |
P17516
P52895 |
| #100100 | Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism |
P20309
|
| #103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
| #203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
| #606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
| #103780 | Alcohol dependence |
P08172
P14416 P31645 |
| #614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
| #600807 | Asthma, susceptibility to |
Q13093
|
| #601816 | Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 |
P22309
|
| #210900 | Bloom syndrome; blm |
P54132
|
| #602025 | Body mass index quantitative trait locus 9; bmiq9 |
P41968
|
| %606641 | Body mass index; bmi |
P37231
|
| #300615 | Brunner syndrome |
P21397
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #609338 | Carotid intimal medial thickness 1 |
P37231
|
| #118300 | Charcot-marie-tooth disease and deafness |
Q01453
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #118220 | Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a |
Q01453
|
| #614466 | Coronary heart disease, susceptibility to, 6; chds6 |
P08254
|
| #218800 | Crigler-najjar syndrome, type i |
P22309
P22310 |
| #606785 | Crigler-najjar syndrome, type ii |
P22309
P22310 |
| #162800 | Cyclic neutropenia |
P08246
|
| #612522 | Diabetes mellitus, insulin-dependent, 22; iddm22 |
P51681
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #607208 | Dravet syndrome |
P18507
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #607681 | Epilepsy, childhood absence, susceptibility to, 2; eca2 |
P18507
|
| #611136 | Epilepsy, juvenile myoclonic, susceptibility to, 5; ejm5 |
P14867
|
| #609820 | Erythrocytosis, familial, 3; ecyt3 |
Q9GZT9
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #613163 | Gaba-transaminase deficiency |
P80404
|
| #613659 | Gastric cancer |
P04626
|
| #137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
| #604233 | Generalized epilepsy with febrile seizures plus, type 1; gefsp1 |
P18507
|
| #611277 | Generalized epilepsy with febrile seizures plus, type 3; gefsp3 |
P18507
|
| #231095 | Ghosal hematodiaphyseal dysplasia; ghdd |
P24557
|
| #143500 | Gilbert syndrome |
P22309
P22310 |
| #137800 | Glioma susceptibility 1; glm1 |
O75874
P04626 P37231 |
| #139393 | Guillain-barre syndrome, familial; gbs |
Q01453
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #609423 | Human immunodeficiency virus type 1, susceptibility to |
P41597
P51681 |
| #143100 | Huntington disease; hd |
P42858
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #237900 | Hyperbilirubinemia, transient familial neonatal; hblrtfn |
P22309
|
| #143860 | Hyperchlorhidrosis, isolated |
O43570
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #145900 | Hypertrophic neuropathy of dejerine-sottas |
Q01453
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #147050 | Ige responsiveness, atopic; iger |
Q13093
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #608232 | Leukemia, chronic myeloid; cml |
P00519
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P00533
P04626 |
| #608516 | Major depressive disorder; mdd |
P08172
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| %300852 | Mental retardation, x-linked 88; mrx88 |
P50052
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #603041 | Mitochondrial dna depletion syndrome 1 (mngie type); mtdps1 |
P19971
|
| #601492 | Mucopolysaccharidosis, type ix; mps9 |
Q12794
|
| #259600 | Multicentric osteolysis, nodulosis, and arthropathy; mona |
P08253
|
| #126200 | Multiple sclerosis, susceptibility to; ms |
P08575
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #159900 | Myoclonic dystonia |
P14416
|
| #162500 | Neuropathy, hereditary, with liability to pressure palsies; hnpp |
Q01453
|
| #202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 |
P08246
|
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #601665 | Obesity |
P32245
P37231 |
| #164230 | Obsessive-compulsive disorder; ocd |
P31645
|
| #604715 | Orthostatic intolerance |
P23975
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #167000 | Ovarian cancer |
P04626
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #613135 | Parkinsonism-dystonia, infantile; pkdys |
Q01959
|
| #172700 | Pick disease of brain |
P10636
|
| #614278 | Platelet-activating factor acetylhydrolase deficiency; pafad |
Q13093
|
| #607276 | Resting heart rate, variation in |
P08588
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #600852 | Retinitis pigmentosa 17; rp17 |
P22748
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #608971 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive |
P08575
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #271980 | Succinic semialdehyde dehydrogenase deficiency; ssadhd |
P51649
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #610460 | Thiopurine s-methyltransferase deficiency |
P51580
|
| #187950 | Thrombocythemia 1; thcyt1 |
P40225
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #190300 | Tremor, hereditary essential, 1; etm1 |
P35462
|
| #610379 | West nile virus, susceptibility to |
P51681
|
| #278300 | Xanthinuria, type i |
P47989
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
| #112100 | Yt blood group antigen |
P22303
|
KEGG DISEASE (82)
| KEGG | name | UniProt |
|---|---|---|
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H01302 | Hyperchlorhidrosis isolated (HCHLH) |
O43570
(related)
|
| H00021 | Renal cell carcinoma |
O43570
(marker)
Q16790 (marker) |
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
P00519
(related)
P00519 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
P00519
(related)
P00519 (marker) |
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P35354 (related) |
| H00018 | Gastric cancer |
P00533
(related)
P04626 (related) |
| H00022 | Bladder cancer |
P00533
(related)
P04626 (related) |
| H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P04626 (related) P08253 (related) |
| H00030 | Cervical cancer |
P00533
(related)
P04626 (related) |
| H00042 | Glioma |
P00533
(related)
P00533 (marker) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) |
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
Q01453 (related) |
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
P37231 (related) |
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04626 (related) Q92731 (marker) |
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04183
(marker)
|
| H00019 | Pancreatic cancer |
P04626
(related)
|
| H00027 | Ovarian cancer |
P04626
(related)
|
| H00031 | Breast cancer |
P04626
(related)
P04626 (marker) |
| H00046 | Cholangiocarcinoma |
P04626
(related)
P35354 (related) |
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00079 | Asthma |
P07550
(related)
|
| H00100 | Neutropenic disorders |
P08246
(related)
|
| H00025 | Penile cancer |
P08253
(related)
P14780 (related) P35354 (related) |
| H00472 | Torg-Winchester syndrome |
P08253
(related)
|
| H00091 | T-B+Severe combined immunodeficiencies (SCIDs) |
P08575
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
| H00038 | Malignant melanoma |
P14679
(marker)
|
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00808 | Idiopathic generalized epilepsies (IGEs) |
P14867
(related)
P18507 (related) |
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00783 | Febrile seizures |
P18507
(related)
|
| H00469 | Mitochondrial DNA depletion syndrome (MDS) |
P19971
(related)
|
| H00548 | Brunner syndrome |
P21397
(related)
|
| H00208 | Hyperbilirubinemia |
P22309
(related)
|
| H00527 | Retinitis pigmentosa (RP) |
P22748
(related)
|
| H01031 | Orthostatic intolerance (OI) |
P23975
(related)
|
| H00490 | Diaphyseal dysplasia with anemia (Ghosal) |
P24557
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00032 | Thyroid cancer |
P37231
(related)
|
| H00409 | Type II diabetes mellitus |
P37231
(related)
|
| H00227 | Congenital amegakaryocytic thrombocytopenia (CAMT) |
P40225
(marker)
|
| H00059 | Huntington's disease (HD) |
P42858
(related)
|
| H00192 | Xanthinuria |
P47989
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
P50052
(related)
Q99714 (related) |
| H00964 | Thiopurine S-methyltransferase deficiency (TPMT deficiency) |
P51580
(related)
|
| H00835 | Succinic semialdehyde dehydrogenase (SSADH) deficiency |
P51649
(related)
|
| H00094 | DNA repair defects |
P54132
(related)
|
| H00296 | Defects in RecQ helicases |
P54132
(related)
|
| H01257 | GABA-transaminase deficiency |
P80404
(related)
|
| H01296 | Hereditary neuropathy with liability to pressure palsies (HNPP) |
Q01453
(related)
|
| H00133 | Mucopolysaccharidosis type IX (MPS9) |
Q12794
(related)
|
| H00421 | Mucopolysaccharidosis (MPS) |
Q12794
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
Q9NUW8 (related) |
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00236 | Congenital polycythemia |
Q9GZT9
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|
Diseases related to CTD interactions
35 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D008545 | Melanoma |
C00002743
C00000152 |
| D012640 | Seizures |
C00002644
|
| D007249 | Inflammation |
C00002743
|
| D008106 | Liver Cirrhosis, Experimental |
C00002743
|
| D050197 | Atherosclerosis |
C00002743
|
| D009203 | Myocardial Infarction |
C00002743
|
| D058739 | Aberrant Crypt Foci |
C00029547
|
| D018248 | Adenoma, Liver Cell |
C00029547
|
| D008113 | Liver Neoplasms |
C00029547
|
| D010212 | Papilloma |
C00029547
|
| D012878 | Skin Neoplasms |
C00029547
|
| D000647 | Amnesia |
C00029533
|
| D007859 | Learning Disorders |
C00029533
|
| D002869 | Chromosome Aberrations |
C00002644
|
| D048629 | Micronuclei, Chromosome-Defective |
C00002644
|
| D009784 | Occupational Diseases |
C00002644
|
| D011041 | Poisoning |
C00002644
|
| D002252 | Carbon Tetrachloride Poisoning |
C00002743
|
| D012220 | Rhinitis |
C00000856
|
| D058186 | Acute Kidney Injury |
C00019698
|
| D001927 | Brain Diseases |
C00019698
|
| D015179 | Colorectal Neoplasms |
C00019698
|
| D003128 | COMA |
C00019698
|
| D064420 | Drug-Related Side Effects and Adverse Reactions |
C00019698
|
| D005076 | Exanthema |
C00019698
|
| D007970 | Leukopenia |
C00019698
|
| D008114 | Liver Neoplasms, Experimental |
C00019698
|
| D052016 | Mucositis |
C00019698
|
| D009336 | Necrosis |
C00019698
|
| D009436 | Neural Tube Defects |
C00019698
|
| D009461 | Neurologic Manifestations |
C00019698
|
| D011297 | Prenatal Exposure Delayed Effects |
C00019698
|
| D051437 | Renal Insufficiency |
C00019698
|
| D013280 | Stomatitis |
C00019698
|
| D013921 | Thrombocytopenia |
C00019698
|