Entry |
|
Symbol |
APC
|
Name |
adenomatosis polyposis coli protein
|
Pathway |
map04550 | Signaling pathways regulating pluripotency of stem cells |
map04810 | Regulation of actin cytoskeleton |
map05022 | Pathways of neurodegeneration - multiple diseases |
|
Disease |
H00044 | Cancer of the anal canal |
H00768 | Autosomal recessive intellectual developmental disorder |
H01025 | Familial adenomatous polyposis |
H01881 | Complex cortical dysplasia with other brain malformations |
H02049 | Bilateral macronodular adrenal hyperplasia |
|
Brite |
KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
K02085 APC; adenomatosis polyposis coli protein
04390 Hippo signaling pathway
K02085 APC; adenomatosis polyposis coli protein
09140 Cellular Processes
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
K02085 APC; adenomatosis polyposis coli protein
09142 Cell motility
04810 Regulation of actin cytoskeleton
K02085 APC; adenomatosis polyposis coli protein
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
K02085 APC; adenomatosis polyposis coli protein
05206 MicroRNAs in cancer
K02085 APC; adenomatosis polyposis coli protein
09162 Cancer: specific types
05210 Colorectal cancer
K02085 APC; adenomatosis polyposis coli protein
05225 Hepatocellular carcinoma
K02085 APC; adenomatosis polyposis coli protein
05226 Gastric cancer
K02085 APC; adenomatosis polyposis coli protein
05217 Basal cell carcinoma
K02085 APC; adenomatosis polyposis coli protein
05213 Endometrial cancer
K02085 APC; adenomatosis polyposis coli protein
05224 Breast cancer
K02085 APC; adenomatosis polyposis coli protein
09172 Infectious disease: viral
05165 Human papillomavirus infection
K02085 APC; adenomatosis polyposis coli protein
09164 Neurodegenerative disease
05010 Alzheimer disease
K02085 APC; adenomatosis polyposis coli protein
05022 Pathways of neurodegeneration - multiple diseases
K02085 APC; adenomatosis polyposis coli protein
09167 Endocrine and metabolic disease
04934 Cushing syndrome
K02085 APC; adenomatosis polyposis coli protein
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins
K02085 APC; adenomatosis polyposis coli protein
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins
K02085 APC; adenomatosis polyposis coli protein
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins
K02085 APC; adenomatosis polyposis coli protein
Protein phosphatases and associated proteins [BR:ko01009]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
K02085 APC; adenomatosis polyposis coli protein
Chromosome and associated proteins [BR:ko03036]
Eukaryotic type
Centrosome formation proteins
Other centriole associated proteins
K02085 APC; adenomatosis polyposis coli protein
Cytoskeleton proteins [BR:ko04812]
Eukaryotic cytoskeleton proteins
Microtubules
Tubulin-binding proteins
EB / APC
K02085 APC; adenomatosis polyposis coli protein
|
Genes |
» show all
|
Reference |
|
Authors |
Kaplan KB, Burds AA, Swedlow JR, Bekir SS, Sorger PK, Nathke IS |
Title |
A role for the Adenomatous Polyposis Coli protein in chromosome segregation. |
Journal |
|
Reference |
|
Authors |
van Es JH, Kirkpatrick C, van de Wetering M, Molenaar M, Miles A, Kuipers J, Destree O, Peifer M, Clevers H |
Title |
Identification of APC2, a homologue of the adenomatous polyposis coli tumour suppressor. |
Journal |
|
Sequence |
|
Reference |
|
Authors |
Joslyn G, Carlson M, Thliveris A, Albertsen H, Gelbert L, Samowitz W, Groden J, Stevens J, Spirio L, Robertson M, et al. |
Title |
Identification of deletion mutations and three new genes at the familial polyposis locus. |
Journal |
|
Sequence |
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