Aeschynanthus bracteatus

• Index
• Plant Species
• Metabolite list (49)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Aeschynanthus bracteatus
Genus	Aeschynanthus
Family	Gesneriaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Aeschynanthus bracteatus
Linked NCBI taxonomy ID	175969
Linked level	species

Family

Family in NCBI taxonomy	Gesneriaceae
ID	26122

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Metabolite list (49)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00014028	Corymboside / 6-alpha-L-Arabinopyranosyl-8-beta-D-galactopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one					No. 1	No. 15
C00000982	Naringenin / (-)-Naringenin	CHEMBL9352 CHEMBL32571	C005273	57 / 46 / 40	35 / 10	No. 25	No. 14
C00033616	Aeschynanthoside D / (-)-Aeschynanthoside D					No. 33
C00033687	Calceolarioside E					No. 33
C00033615	Aeschynanthoside C / (-)-Aeschynanthoside C					No. 33
C00033613	Aeschynanthoside A / (-)-Aeschynanthoside A					No. 33
C00002783	Kusaginin / Acteoside / Verbascoside	CHEMBL231853 CHEMBL444478 CHEMBL1364101	C058956	12 / 1 / 1	34 / 3	No. 33
C00033958	Isonuomioside A					No. 33
C00033614	Aeschynanthoside B / (-)-Aeschynanthoside B					No. 33
C00033950	Icariol A2 / (-)-Icariol A2	CHEMBL466534				No. 38	No. 21
C00033556	3,4-Dihydroxyphenethyl glucoside / (-)-3,4-Dihydroxyphenethyl glucoside	CHEMBL1689261		1 / 0 / 3		No. 45	No. 72
C00034184	Pyrroside B					No. 48	No. 14
C00033567	4-Epipinfaensin / 4-epi-Pinfaensin					No. 50	No. 51
C00034098	Paradrymonoside / (+)-Paradrymonoside					No. 50	No. 51
C00034295	Suavissimoside F1 / (-)-Suavissimoside F1					No. 50	No. 51
C00000631	trans-Dihydrodehydrodiconiferyl alcohol-9-O-beta-D-glucoside	CHEMBL466931				No. 193
C00033622	Alaschanioside C	CHEMBL1086907				No. 193
C00033656	Balanophonin / (-)-Balanophonin	CHEMBL253335 CHEMBL468666 CHEMBL590760 CHEMBL1956166				No. 215	No. 23
C00006091	Hemiphloin / 6-C-Glucosylnaringenin / (S)-6-beta-D-Glucopyranosyl-4',5,7-trihydroxyflavanone / (2S)-6-beta-D-Glucopyranosyl-2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one	CHEMBL562199 CHEMBL1645374	C066406			No. 261	No. 14
C00000614	Coniferyl alcohol	CHEMBL501870 CHEMBL2088631	C010559			No. 310	No. 6
C00031384	Sinapinaldehyde	CHEMBL225067				No. 310	No. 6
C00002728	Coniferaldehyde / Coniferyl aldehyde / 4-Hydroxy-3-methoxycinnamaldehyde	CHEMBL242529 CHEMBL1956165	C075384	1 / 1 / 1		No. 310	No. 6
C00033554	2-Methoxy-4-(3-methoxy-1-propenyl)-phenol					No. 310	No. 6
C00034298	Syringenin	CHEMBL1800816				No. 310	No. 6
C00033685	Calceolarioside A	CHEMBL481635	C083066	1 / 0 / 0		No. 382
C00033686	Calceolarioside B	CHEMBL518414		3 / 2 / 5		No. 382
C00034207	Sanangoside					No. 382
C00006430	Ormocarpin					No. 521
C00033999	Koaburaside	CHEMBL513117		2 / 4 / 2		No. 678	No. 6
C00000856	4-Hydroxybenzoic acid / p-Hydroxybenzoic acid	CHEMBL441343	C038193	21 / 7 / 16	2 / 1	No. 817	No. 81
C00007558	Syringaldehyde / 4-Hydroxy-3,5-dimethoxybenzaldehyde	CHEMBL225303	C069665			No. 856
C00029961	Cinnamic acid / .beta-Phenylacrylic acid	CHEMBL27246	C029010	5 / 2 / 2	16 / 2	No. 904	No. 6
C00002683	Vanillin	CHEMBL13883		18 / 8 / 9		No. 1003
C00029479	Veratric acid / 3,4-dimethoxybenzoic acid	CHEMBL118903	C009333	10 / 6 / 6		No. 1073
C00033516	1,3-Dihydroxy-1-(4-hydroxy-3,5-dimethoxyphenyl)propan-2-one					No. 1180
C00002743	Ferulic acid / 3-(4-Hydroxy-3-methoxyphenyl)-2-propenoic acid	CHEMBL32749	C004999	110 / 52 / 40	16 / 6	No. 1366	No. 6
C00033897	Guaiacylglycerol-beta-ferulic acid ether					No. 1504
C00033510	1-(2-Hydroxy-5-methoxyphenyl)-1,2-propanediol					No. 1736
C00033837	Ethylparaben	CHEMBL15841	C012313	11 / 10 / 9	4 / 1	No. 2169
C00033844	Evofolin B / (-)-Evofolin B	CHEMBL448601 CHEMBL602133				No. 2211
C00033819	Epidihydrophaseic acid					No. 2610	No. 38
C00002698	Piceol / p-Hydroxyacetophenone / 4'-Hydroxyacetophenone	CHEMBL201083	C031335	5 / 3 / 3		No. 2849
C00033557	3,4'-Dihydroxypropiophenone	CHEMBL1417159		25 / 10 / 7		No. 2849
C00029477	beta-Hydroxypropiovanillone / omega-Hydroxypropioguaiacone / 3,4'-Dihydroxy-3'-methoxypropiophenone / 3-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone	CHEMBL485875				No. 2959
C00033738	C-veratroylglycol	CHEMBL590536				No. 2959
C00030712	Dianthoside / (-)-Dianthoside / Maltol glucoside / Maltol beta-D-glucopyranoside	CHEMBL485278				No. 3335
C00033589	7-Octene-1,6-diol					No. 3536
C00033511	1-(3,4-Dimethoxyphenyl)-1,3-propanediol					No. 5078
C00031831	Grasshopper ketone / (-)-Grasshopper ketone	CHEMBL456946				No. 5414

Human Protein / Gene in interactions

188 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P43166	Carbonic anhydrase 7	Lyase	C00000856 C00002743 C00029479 C00033837	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00002743 C00002783 C00033685 C00033686	0 / 0
Q16790	Carbonic anhydrase 9	Lyase	C00000856 C00002743 C00029479 C00033837	0 / 1
Q9ULX7	Carbonic anhydrase 14	Lyase	C00000856 C00002743 C00029479 C00033837	0 / 0
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00000982 C00002728 C00002743 C00029961	1 / 1
O43570	Carbonic anhydrase 12	Lyase	C00000856 C00002743 C00029479 C00033837	1 / 2
P19224	UDP-glucuronosyltransferase 1-6	Enzyme	C00000856 C00002683 C00002698 C00033837	0 / 0
O60656	UDP-glucuronosyltransferase 1-9	Enzyme	C00000856 C00002683 C00002698 C00033837	0 / 0
P00915	Carbonic anhydrase 1	Lyase	C00000856 C00002743 C00029479 C00033837	0 / 0
P00918	Carbonic anhydrase 2	Lyase	C00000856 C00002743 C00029479 C00033837	1 / 2
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00000982 C00002743 C00033556 C00033686	0 / 3
P22748	Carbonic anhydrase 4	Lyase	C00000856 C00002743 C00029479	1 / 1
Q9HAW8	UDP-glucuronosyltransferase 1-10	Enzyme	C00000856 C00000982 C00002683	0 / 0
P10275	Androgen receptor	NR3C4	C00000982 C00002683 C00033837	3 / 4
P51649	Succinate-semialdehyde dehydrogenase, mitochondrial	Oxidoreductase	C00000856 C00002683 C00002698	1 / 1
O75496	Geminin	Unclassified protein	C00000982 C00002743 C00002783	0 / 0
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00000982 C00002743 C00033837	5 / 1
P80404	4-aminobutyrate aminotransferase, mitochondrial	Transferase	C00000856 C00002683 C00002698	1 / 1
Q9UNA4	DNA polymerase iota	Enzyme	C00000982 C00002783 C00033557	0 / 0
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00000982 C00029961 C00033999	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00000982 C00002683 C00033557	1 / 1
P03372	Estrogen receptor	NR3A1	C00000982 C00002743 C00029961	1 / 1
P23280	Carbonic anhydrase 6	Lyase	C00000856 C00002743 C00029479	0 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00002683 C00002783 C00033557	0 / 0
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00000982 C00002743	0 / 0
Q9Y2D0	Carbonic anhydrase 5B, mitochondrial	Lyase	C00000856 C00002743	0 / 0
P22303	Acetylcholinesterase	Hydrolase	C00000982 C00002743	1 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00000982 C00002743	0 / 0
P51580	Thiopurine S-methyltransferase	Enzyme	C00000856 C00029479	1 / 1
P35218	Carbonic anhydrase 5A, mitochondrial	Lyase	C00000856 C00002743	0 / 0
Q9HAW9	UDP-glucuronosyltransferase 1-8	Enzyme	C00000856 C00000982	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00000982 C00002743	1 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00000982 C00002743	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000982 C00002743	0 / 1
O75164	Lysine-specific demethylase 4A	Enzyme	C00002783 C00033557	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00002683 C00033837	0 / 0
P07451	Carbonic anhydrase 3	Lyase	C00000856 C00002743	0 / 0
P11511	Cytochrome P450 19A1	Cytochrome P450 19A1	C00000982 C00033686	2 / 2
P04150	Glucocorticoid receptor	NR3C1	C00000982 C00002743	0 / 1
P83916	Chromobox protein homolog 1	Unclassified protein	C00002783 C00033557	0 / 0
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00002783 C00033557	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00002783 C00033557	0 / 0
P15121	Aldose reductase	Enzyme	C00000982 C00029961	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00000982 C00002743	0 / 1
P41143	Delta-type opioid receptor	Opioid receptor	C00000982 C00002743	0 / 0
P34969	5-hydroxytryptamine receptor 7	Serotonin receptor	C00002683 C00002743	0 / 0
P54855	UDP-glucuronosyltransferase 2B15	Enzyme	C00000982 C00002743	0 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00002783 C00033557	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00002743 C00033557	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00002783 C00033557	0 / 0
Q8TDS4	Hydroxycarboxylic acid receptor 2	Hydroxycarboxylic acid receptor	C00002743 C00029961	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00002783 C00033557	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00000982 C00002743	0 / 1
P00352	Retinal dehydrogenase 1	Enzyme	C00002683 C00033557	0 / 0
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00000982 C00002743	3 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000982 C00002743	1 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00000982 C00002743	0 / 0
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00000856 C00002743	1 / 8
Q9HAW7	UDP-glucuronosyltransferase 1-7	Enzyme	C00000856 C00002683	0 / 0
P30411	B2 bradykinin receptor	Bradykinin receptor	C00002743	0 / 0
P14416	D(2) dopamine receptor	Dopamine receptor	C00002743	2 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00002743	0 / 0
P37288	Vasopressin V1a receptor	Vasopressin and oxytocin receptor	C00002743	0 / 0
P54132	Bloom syndrome protein	Enzyme	C00033557	1 / 2
Q9Y271	Cysteinyl leukotriene receptor 1	Leukotriene receptor	C00002743	0 / 0
P29274	Adenosine receptor A2a	Adenosine receptor	C00002743	0 / 0
O75828	Carbonyl reductase [NADPH] 3	Enzyme	C00000982	0 / 0
P25929	Neuropeptide Y receptor type 1	Neuropeptide Y receptor	C00002743	0 / 0
P50052	Type-2 angiotensin II receptor	Angiotensin receptor	C00002743	1 / 1
P17948	Vascular endothelial growth factor receptor 1	Vegfr	C00002743	0 / 0
P41968	Melanocortin receptor 3	Melanocortin receptor	C00002743	1 / 0
P24864	G1/S-specific cyclin-E1	Other cytosolic protein	C00000982	0 / 2
P24941	Cyclin-dependent kinase 2	Cdc2	C00000982	0 / 0
Q08209	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Ser_Thr	C00002743	0 / 0
P04278	Sex hormone-binding globulin	Secreted protein	C00000982	0 / 0
P36888	Receptor-type tyrosine-protein kinase FLT3	Pdgfr	C00000982	1 / 1
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00002743	0 / 0
P06241	Tyrosine-protein kinase Fyn	Src	C00002743	0 / 0
Q9UQ49	Sialidase-3	Enzyme	C00000856	0 / 0
P16152	Carbonyl reductase [NADPH] 1	Enzyme	C00000982	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00029479	2 / 0
P25024	C-X-C chemokine receptor type 1	CXC chemokine receptor	C00002743	0 / 0
P08183	Multidrug resistance protein 1	drug	C00000982	1 / 0
P04798	Cytochrome P450 1A1	Cytochrome P450 1A1	C00000982	0 / 0
P04035	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oxidoreductase	C00002743	0 / 0
P08913	Alpha-2A adrenergic receptor	Adrenergic receptor	C00002743	0 / 0
P21917	D(4) dopamine receptor	Dopamine receptor	C00002743	0 / 0
P30988	Calcitonin receptor	Calcitonin receptor	C00002743	0 / 0
P35462	D(3) dopamine receptor	Dopamine receptor	C00002743	1 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00002743	0 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00002743	0 / 0
P41595	5-hydroxytryptamine receptor 2B	Serotonin receptor	C00002743	0 / 0
P08912	Muscarinic acetylcholine receptor M5	Acetylcholine receptor	C00002743	0 / 0
P25101	Endothelin-1 receptor	Endothelin receptor	C00002743	0 / 0
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00033557	1 / 0
P32245	Melanocortin receptor 4	Melanocortin receptor	C00002743	1 / 0
Q01959	Sodium-dependent dopamine transporter	Dopamine	C00002743	1 / 0
P32238	Cholecystokinin receptor type A	Cholecystokinin receptor	C00002743	0 / 0
P08311	Cathepsin G	S1A	C00002743	0 / 0
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00002743	1 / 0
O00519	Fatty-acid amide hydrolase 1	Enzyme	C00002683	0 / 0
P03956	Interstitial collagenase	M10A	C00002743	0 / 1
P32241	Vasoactive intestinal polypeptide receptor 1	Vasoactive intestinal peptide receptor	C00002743	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00033557	1 / 1
P09923	Intestinal-type alkaline phosphatase	Enzyme	C00033557	0 / 0
P05186	Alkaline phosphatase, tissue-nonspecific isozyme	Enzyme	C00033557	3 / 1
P35367	Histamine H1 receptor	Histamine receptor	C00002743	0 / 0
P25021	Histamine H2 receptor	Histamine receptor	C00002743	0 / 0
Q9NPD5	Solute carrier organic anion transporter family member 1B3	Electrochemical transporter	C00000982	1 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00000982	0 / 0
P00734	Prothrombin	S1A	C00033999	4 / 2
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00002743	1 / 1
P08172	Muscarinic acetylcholine receptor M2	Acetylcholine receptor	C00002743	2 / 0
P11229	Muscarinic acetylcholine receptor M1	Acetylcholine receptor	C00002743	0 / 0
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00002743	0 / 1
P14679	Tyrosinase	Oxidoreductase	C00002743	4 / 2
P21554	Cannabinoid receptor 1	Cannabinoid receptor	C00002743	0 / 0
P31645	Sodium-dependent serotonin transporter	Serotonin	C00002743	2 / 0
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00000982	5 / 3
P19793	Retinoic acid receptor RXR-alpha	NR2B1	C00002683	0 / 0
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00002743	5 / 9
P20309	Muscarinic acetylcholine receptor M3	Acetylcholine receptor	C00002743	1 / 0
Q16678	Cytochrome P450 1B1	Cytochrome P450 1B1	C00000982	4 / 4
P21452	Substance-K receptor	Neurokinin receptor	C00002743	0 / 0
P51679	C-C chemokine receptor type 4	CC chemokine receptor	C00002743	0 / 0
P51681	C-C chemokine receptor type 5	CC chemokine receptor	C00002743	3 / 0
P50406	5-hydroxytryptamine receptor 6	Serotonin receptor	C00002743	0 / 0
P04745	Alpha-amylase 1	Enzyme	C00000982	0 / 0
P18054	Arachidonate 12-lipoxygenase, 12S-type	Enzyme	C00000982	2 / 0
Q96RI1	Bile acid receptor	NR1H4	C00002683	0 / 0
P37058	Testosterone 17-beta-dehydrogenase 3	Enzyme	C00002698	1 / 1
P41597	C-C chemokine receptor type 2	CC chemokine receptor	C00002743	1 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00002743	0 / 0
P10696	Alkaline phosphatase, placental-like	Enzyme	C00033557	0 / 1
P08575	Receptor-type tyrosine-protein phosphatase C	Enzyme	C00002743	2 / 1
P62158	Calmodulin	Unclassified protein	C00000982	1 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00033557	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00000982	3 / 3
Q9UNQ0	ATP-binding cassette sub-family G member 2	ATP binding cassette	C00000982	2 / 0
Q92887	Canalicular multispecific organic anion transporter 1	Unclassified protein	C00000982	1 / 1
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00002683	2 / 2
P14780	Matrix metalloproteinase-9	M10A	C00002743	2 / 2
Q9Y4X1	UDP-glucuronosyltransferase 2A1	Enzyme	C00002683	0 / 0
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00000982	0 / 0
P27361	Mitogen-activated protein kinase 3	Erk	C00002743	0 / 0
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00002743	1 / 0
P29466	Caspase-1	C14	C00002743	0 / 0
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00002743	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00002743	0 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00033557	1 / 1
P08173	Muscarinic acetylcholine receptor M4	Acetylcholine receptor	C00002743	0 / 0
P25103	Substance-P receptor	Neurokinin receptor	C00002743	0 / 0
P25105	Platelet-activating factor receptor	PAF receptor	C00002743	0 / 0
P33032	Melanocortin receptor 5	Melanocortin receptor	C00002743	0 / 0
P04062	Glucosylceramidase	Enzyme	C00000982	6 / 4
P49146	Neuropeptide Y receptor type 2	Neuropeptide Y receptor	C00002743	0 / 0
P37059	Estradiol 17-beta-dehydrogenase 2	Enzyme	C00000982	0 / 0
P06746	DNA polymerase beta	Enzyme	C00033557	0 / 0
P05181	Cytochrome P450 2E1	Cytochrome P450 2E1	C00002743	0 / 0
Q16539	Mitogen-activated protein kinase 14	p38	C00002743	0 / 0
Q13093	Platelet-activating factor acetylhydrolase	Enzyme	C00002743	3 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00033557	0 / 0
P78527	DNA-dependent protein kinase catalytic subunit	Atypical serine/threonine protein kinase PIKK subfamily	C00002683	0 / 0
P33765	Adenosine receptor A3	Adenosine receptor	C00002743	0 / 0
P08246	Neutrophil elastase	S1A	C00002743	2 / 1
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00002743	2 / 2
P23975	Sodium-dependent noradrenaline transporter	Norepinephrine	C00002743	1 / 1
P25100	Alpha-1D adrenergic receptor	Adrenergic receptor	C00002743	0 / 0
P30542	Adenosine receptor A1	Adenosine receptor	C00002743	0 / 0
Q07869	Peroxisome proliferator-activated receptor alpha	NR1C1	C00000982	0 / 0
P18089	Alpha-2B adrenergic receptor	Adrenergic receptor	C00002743	0 / 0
P24557	Thromboxane-A synthase	Cytochrome P450 5A1	C00002743	1 / 1
P21728	D(1A) dopamine receptor	Dopamine receptor	C00002743	0 / 0
P06239	Tyrosine-protein kinase Lck	Src	C00002743	0 / 1
Q04760	Lactoylglutathione lyase	Enzyme	C00000982	0 / 0
P25025	C-X-C chemokine receptor type 2	CXC chemokine receptor	C00002743	0 / 0
P49888	Estrogen sulfotransferase	Enzyme	C00000982	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00002783	1 / 1
Q12794	Hyaluronidase-1	Enzyme	C00002743	1 / 2
O94956	Solute carrier organic anion transporter family member 2B1	Unclassified protein	C00000982	0 / 0
Q9Y6L6	Solute carrier organic anion transporter family member 1B1	Electrochemical transporter	C00000982	1 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00033557	0 / 0
Q07820	Induced myeloid leukemia cell differentiation protein Mcl-1	Other cytosolic protein	C00033557	0 / 0
P33527	Multidrug resistance-associated protein 1	drugs	C00000982	0 / 0
O00255	Menin	Unclassified protein	C00000982	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00000982	1 / 2
P14061	Estradiol 17-beta-dehydrogenase 1	Enzyme	C00000982	0 / 0
Q14191	Werner syndrome ATP-dependent helicase	Enzyme	C00033557	2 / 1

79 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
7299	TYR, ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3	tyrosinase (EC:1.14.18.1)	C00002743 C00029961 C00033837
54576	UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H	UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17)	C00000982 C00002743 C00029961
54577	UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G	UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17)	C00000982 C00002743 C00029961
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00000982 C00002743 C00002783
54575	UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J	UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17)	C00000982 C00002743 C00029961
196	AHR, bHLHe76	aryl hydrocarbon receptor	C00000982 C00002783
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00002743 C00002783
3952	LEP, LEPD, OB, OBS	leptin	C00000856 C00033837
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00002743 C00002783
5925	RB1, OSRC, RB, p105-Rb, pRb, pp110	retinoblastoma 1	C00002743 C00002783
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00000982 C00002783
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00002743 C00002783
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00000982 C00002743
54659	UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C	UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17)	C00002743 C00029961
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00002743 C00002783
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00002743 C00002783
6817	SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1)	C00000856 C00000982
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00000982 C00002783
2100	ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2	estrogen receptor 2 (ER beta)	C00000982 C00033837
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00000982 C00033837
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00000982 C00029961
1559	CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9	cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00000982 C00029961
405	ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2	aryl hydrocarbon receptor nuclear translocator	C00000982 C00002783
23621	BACE1, ASP2, BACE, HSPC104	beta-site APP-cleaving enzyme 1 (EC:3.4.23.46)	C00002743
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00000982
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00000982
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00000982
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00000982
1588	CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM	cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00000982
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00000982
8644	AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS	aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357)	C00000982
1645	AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB	aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112)	C00000982
249	ALPL, AP-TNAP, APTNAP, HOPS, TNAP, TNSALP	alkaline phosphatase, liver/bone/kidney (EC:3.1.3.1)	C00000982
10057	ABCC5, ABC33, EST277145, MOAT-C, MOATC, MRP5, SMRP, pABC11	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	C00000982
10257	ABCC4, EST170205, MOAT-B, MOATB, MRP4	ATP-binding cassette, sub-family C (CFTR/MRP), member 4	C00000982
3757	KCNH2, ERG1, HERG, HERG1, Kv11.1, LQT2, SQT1	potassium voltage-gated channel, subfamily H (eag-related), member 2	C00000982
5444	PON1, ESA, MVCD5, PON	paraoxonase 1 (EC:3.1.1.2 3.1.8.1 3.1.1.81)	C00000982
6566	SLC16A1, HHF7, MCT, MCT1	solute carrier family 16 (monocarboxylate transporter), member 1	C00000982
6513	SLC2A1, DYT17, DYT18, DYT9, EIG12, GLUT, GLUT1, GLUT1DS, HTLVR, PED	solute carrier family 2 (facilitated glucose transporter), member 1	C00000982
4363	ABCC1, ABC29, ABCC, GS-X, MRP, MRP1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	C00000982
6818	SULT1A3, HAST, HAST3, M-PST, ST1A3/ST1A4, ST1A5, STM, TL-PST	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 (EC:2.8.2.1)	C00000982
6319	SCD, FADS5, MSTP008, SCD1, SCDOS	stearoyl-CoA desaturase (delta-9-desaturase) (EC:1.14.19.1)	C00002743
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00000982
54658	UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A	UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17)	C00000982
54600	UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I	UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17)	C00000982
7366	UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8	UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17)	C00000982
5742	PTGS1, COX1, COX3, PCOX1, PES-1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00002743
1586	CYP17A1, CPT7, CYP17, P450C17, S17AH	cytochrome P450, family 17, subfamily A, polypeptide 1 (EC:1.14.99.9 4.1.2.30)	C00029961
1548	CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB	cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1)	C00029961
1557	CYP2C19, CPCJ, CYP2C, P450C2C, P450IIC19	cytochrome P450, family 2, subfamily C, polypeptide 19 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00029961
1558	CYP2C8, CPC8, CYPIIC8, MP-12/MP-20	cytochrome P450, family 2, subfamily C, polypeptide 8 (EC:1.14.14.1)	C00029961
1565	CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1	cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1)	C00029961
1571	CYP2E1, CPE1, CYP2E, P450-J, P450C2E	cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7)	C00029961
338442	HCAR2, GPR109A, HCA2, HM74a, HM74b, NIACR1, PUMAG, Puma-g	hydroxycarboxylic acid receptor 2	C00029961
3284	HSD3B2, HSD3B, HSDB, SDR11E2	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 (EC:1.1.1.145 5.3.3.1)	C00029961
4846	NOS3, ECNOS, eNOS	nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39)	C00029961
6347	CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF	chemokine (C-C motif) ligand 2	C00002783
894	CCND2, KIAK0002	cyclin D2	C00002783
896	CCND3	cyclin D3	C00002783
898	CCNE1, CCNE	cyclin E1	C00002783
1017	CDK2, p33(CDK2)	cyclin-dependent kinase 2 (EC:2.7.11.22)	C00002783
1019	CDK4, CMM3, PSK-J3	cyclin-dependent kinase 4 (EC:2.7.11.22)	C00002783
1021	CDK6, PLSTIRE	cyclin-dependent kinase 6 (EC:2.7.11.22)	C00002783
1027	CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	C00002783
3627	CXCL10, C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1	chemokine (C-X-C motif) ligand 10	C00002783
1869	E2F1, E2F-1, RBAP1, RBBP3, RBP3	E2F transcription factor 1	C00002783
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00002783
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00002783
3458	IFNG, IFG, IFI	interferon, gamma	C00002783
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00002783
3689	ITGB2, CD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	C00002783
27035	NOX1, GP91-2, MOX1, NOH-1, NOH1	NADPH oxidase 1	C00002783
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00002783
4087	SMAD2, JV18, JV18-1, MADH2, MADR2, hMAD-2, hSMAD2	SMAD family member 2	C00002783
4088	SMAD3, HSPC193, HsT17436, JV15-2, LDS1C, LDS3, MADH3	SMAD family member 3	C00002783
6648	SOD2, IPOB, MNSOD, MVCD6	superoxide dismutase 2, mitochondrial (EC:1.15.1.1)	C00002783
7039	TGFA, TFGA	transforming growth factor, alpha	C00002783
7040	TGFB1, CED, DPD1, LAP, TGFB, TGFbeta	transforming growth factor, beta 1	C00002783
7412	VCAM1, CD106, INCAM-100	vascular cell adhesion molecule 1	C00002783

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