 09100 Metabolism
|
|
09101 Carbohydrate metabolism
|
 00010 Glycolysis / Gluconeogenesis [PATH:ko00010]
|
00020 Citrate cycle (TCA cycle) [PATH:ko00020]
|
00030 Pentose phosphate pathway [PATH:ko00030]
|
00040 Pentose and glucuronate interconversions [PATH:ko00040]
|
00051 Fructose and mannose metabolism [PATH:ko00051]
|
00052 Galactose metabolism [PATH:ko00052]
|
00053 Ascorbate and aldarate metabolism [PATH:ko00053]
|
00500 Starch and sucrose metabolism [PATH:ko00500]
|
00520 Amino sugar and nucleotide sugar metabolism [PATH:ko00520]
|
00620 Pyruvate metabolism [PATH:ko00620]
|
00630 Glyoxylate and dicarboxylate metabolism [PATH:ko00630]
|
00640 Propanoate metabolism [PATH:ko00640]
|
00650 Butanoate metabolism [PATH:ko00650]
|
00660 C5-Branched dibasic acid metabolism [PATH:ko00660]
|
00562 Inositol phosphate metabolism [PATH:ko00562]
|
 K00914 PIK3C3, VPS34; phosphatidylinositol 3-kinase [EC:2.7.1.137]
K01108 MTM1; myotubularin [EC:3.1.3.64 3.1.3.95]
K18081 MTMR1_2; myotubularin-related protein 1/2 [EC:3.1.3.64 3.1.3.95]
K18082 MTMR3_4, ZFYVE10_11; myotubularin-related protein 3/4 [EC:3.1.3.48 3.1.3.64 3.1.3.95]
K18083 MTMR6_7_8; myotubularin-related protein 6/7/8 [EC:3.1.3.64 3.1.3.95]
K18086 MTMR14; myotubularin-related protein 14 [EC:3.1.3.64 3.1.3.95]
K21302 sapM; phosphatidylinositol-3-phosphatase [EC:3.1.3.64]
K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
K19801 PI4KB; phosphatidylinositol 4-kinase B [EC:2.7.1.67]
K13711 PI4K2; phosphatidylinositol 4-kinase type 2 [EC:2.7.1.67]
K21797 SAC1, SACM1L; phosphatidylinositol 4-phosphatase [EC:3.1.3.-]
K21798 SAC2, INPP5F; phosphatidylinositol 4-phosphatase [EC:3.1.3.-]
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K13712 PIP5KL1; phosphatidylinositol-4-phosphate 5-kinase-like protein 1 [EC:2.7.1.68]
K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
K20278 INPP5E; inositol polyphosphate 5-phosphatase INPP5E [EC:3.1.3.36]
K20279 SYNJ; synaptojanin [EC:3.1.3.36]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K21289 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K03084 SHIP1, INPP5D; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 [EC:3.1.3.86]
K15909 SHIP2, INPPL1; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 [EC:3.1.3.86]
K00923 PIK3C2; phosphatidylinositol-4-phosphate 3-kinase [EC:2.7.1.154]
K01109 INPP4; inositol polyphosphate-4-phosphatase [EC:3.1.3.66]
K00921 PIKFYVE, FAB1; 1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150]
K22913 FIG4; phosphatidylinositol 3,5-bisphosphate 5-phosphatase [EC:3.1.3.-]
K00920 PIP4K2; 1-phosphatidylinositol-5-phosphate 4-kinase [EC:2.7.1.149]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
K05860 PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K05861 PLCZ; phosphatidylinositol phospholipase C, zeta [EC:3.1.4.11]
K19006 PLCH; phosphatidylinositol phospholipase C, eta [EC:3.1.4.11]
K01114 plc; phospholipase C [EC:3.1.4.3]
K16619 plc, cpa; phospholipase C / alpha-toxin [EC:3.1.4.3]
K01771 plc; 1-phosphatidylinositol phosphodiesterase [EC:4.6.1.13]
K01092 E3.1.3.25, IMPA, suhB; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
K10047 VTC4; inositol-phosphate phosphatase / L-galactose 1-phosphate phosphatase [EC:3.1.3.25 3.1.3.93]
K18649 IMPL2; inositol-phosphate phosphatase / L-galactose 1-phosphate phosphatase / histidinol-phosphatase [EC:3.1.3.25 3.1.3.93 3.1.3.15]
K00999 CDIPT; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [EC:2.7.8.11]
K01858 INO1, ISYNA1; myo-inositol-1-phosphate synthase [EC:5.5.1.4]
K01107 INPP1; inositol polyphosphate 1-phosphatase [EC:3.1.3.57]
K15422 SAL; 3'(2'), 5'-bisphosphate nucleotidase / inositol polyphosphate 1-phosphatase [EC:3.1.3.7 3.1.3.57]
K19517 MIK; 1D-myo-inositol 3-kinase [EC:2.7.1.64]
K01106 INPP5A; inositol polyphosphate 5-phosphatase INPP5A [EC:3.1.3.56]
K24222 INPP5J_K; inositol polyphosphate 5-phosphatase INPP5J/K [EC:3.1.3.56]
K24221 IP5P1_2; type I inositol polyphosphate 5-phosphatase IP5P1/2 [EC:3.1.3.56]
K03103 MINPP1; multiple inositol-polyphosphate phosphatase / 2,3-bisphosphoglycerate 3-phosphatase [EC:3.1.3.62 3.1.3.80]
K00911 ITPK; 1D-myo-inositol-triphosphate 3-kinase [EC:2.7.1.127]
K00913 ITPK1; inositol-1,3,4-trisphosphate 5/6-kinase / inositol-tetrakisphosphate 1-kinase [EC:2.7.1.159 2.7.1.134]
K01765 ITPK4; inositol-1,3,4-trisphosphate 5/6-kinase [EC:2.7.1.159]
K00915 IPMK, IPK2; inositol-polyphosphate multikinase [EC:2.7.1.140 2.7.1.151]
K10572 IPPK; inositol-pentakisphosphate 2-kinase [EC:2.7.1.158]
K19786 IPK1; inositol-pentakisphosphate 2-kinase [EC:2.7.1.158]
K01083 E3.1.3.8; 3-phytase [EC:3.1.3.8]
K01093 appA; 4-phytase / acid phosphatase [EC:3.1.3.26 3.1.3.2]
K23992 K23992; 1L-myo-inositol 1-phosphate cytidylyltransferase / CDP-L-myo-inositol myo-inositolphosphotransferase [EC:2.7.7.74 2.7.8.34]
K07281 ipct; 1L-myo-inositol 1-phosphate cytidylyltransferase [EC:2.7.7.74]
K07291 dipps; CDP-L-myo-inositol myo-inositolphosphotransferase [EC:2.7.8.34]
K00469 MIOX; inositol oxygenase [EC:1.13.99.1]
K00010 iolG; myo-inositol 2-dehydrogenase / D-chiro-inositol 1-dehydrogenase [EC:1.1.1.18 1.1.1.369]
K06606 iolI; 2-keto-myo-inositol isomerase [EC:5.3.99.11]
K16043 iolX; scyllo-inositol 2-dehydrogenase (NAD+) [EC:1.1.1.370]
K16044 iolW; scyllo-inositol 2-dehydrogenase (NADP+) [EC:1.1.1.371]
K22230 iolU; scyllo-inositol 2-dehydrogenase (NADP+) [EC:1.1.1.-]
K22231 iolM; scyllo-inosose 3-dehydrogenase [EC:1.1.1.-]
K22232 iolN; 3-dehydro-scyllo-inosose hydrolase [EC:3.7.1.-]
K22233 iolO; 5-keto-L-gluconate epimerase [EC:5.1.-.-]
K03335 iolE; inosose dehydratase [EC:4.2.1.44]
K03336 iolD; 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing) [EC:3.7.1.22]
K03337 iolB; 5-deoxy-glucuronate isomerase [EC:5.3.1.30]
K03338 iolC; 5-dehydro-2-deoxygluconokinase [EC:2.7.1.92]
K03339 iolJ; 6-phospho-5-dehydro-2-deoxy-D-gluconate aldolase [EC:4.1.2.29]
K00140 mmsA, iolA, ALDH6A1; malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27]
K01803 TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1]
|
|
09102 Energy metabolism
|
|
09103 Lipid metabolism
|
|
09104 Nucleotide metabolism
|
|
09105 Amino acid metabolism
|
|
09106 Metabolism of other amino acids
|
|
09107 Glycan biosynthesis and metabolism
|
|
09108 Metabolism of cofactors and vitamins
|
|
09109 Metabolism of terpenoids and polyketides
|
|
09110 Biosynthesis of other secondary metabolites
|
|
09111 Xenobiotics biodegradation and metabolism
|
|
09112 Not included in regular maps
|
|
09120 Genetic Information Processing
|
|
09130 Environmental Information Processing
|
|
09131 Membrane transport
|
|
09132 Signal transduction
|
02020 Two-component system [PATH:ko02020]
|
04010 MAPK signaling pathway [PATH:ko04010]
|
04013 MAPK signaling pathway - fly [PATH:ko04013]
|
04016 MAPK signaling pathway - plant [PATH:ko04016]
|
04011 MAPK signaling pathway - yeast [PATH:ko04011]
|
04012 ErbB signaling pathway [PATH:ko04012]
|
04014 Ras signaling pathway [PATH:ko04014]
|
04015 Rap1 signaling pathway [PATH:ko04015]
|
04310 Wnt signaling pathway [PATH:ko04310]
|
04330 Notch signaling pathway [PATH:ko04330]
|
04340 Hedgehog signaling pathway [PATH:ko04340]
|
04341 Hedgehog signaling pathway - fly [PATH:ko04341]
|
04350 TGF-beta signaling pathway [PATH:ko04350]
|
04390 Hippo signaling pathway [PATH:ko04390]
|
04391 Hippo signaling pathway - fly [PATH:ko04391]
|
04392 Hippo signaling pathway - multiple species [PATH:ko04392]
|
04370 VEGF signaling pathway [PATH:ko04370]
|
04371 Apelin signaling pathway [PATH:ko04371]
|
04630 JAK-STAT signaling pathway [PATH:ko04630]
|
04064 NF-kappa B signaling pathway [PATH:ko04064]
|
04668 TNF signaling pathway [PATH:ko04668]
|
04066 HIF-1 signaling pathway [PATH:ko04066]
|
04068 FoxO signaling pathway [PATH:ko04068]
|
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04501 SMAD4; mothers against decapentaplegic homolog 4
K23605 SMAD3; mothers against decapentaplegic homolog 3
K07298 STK11, LKB1; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K07198 PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K04468 NLK; nemo like kinase [EC:2.7.11.24]
K03875 SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K11431 SETD7; [histone H3]-lysine4 N-methyltransferase [EC:2.1.1.364]
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K11411 SIRT1, SIR2L1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K11838 USP7, UBP15; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
K07191 SLC2A4, GLUT4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04411 STK4, MST1; serine/threonine kinase 4
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04526 INS; insulin
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K17445 IRS3; insulin receptor substrate 3
K17446 IRS4; insulin receptor substrate 4
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K13302 SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
K13303 SGK2; serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
K13304 SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K12358 FOXO4; forkhead box protein O4
K17847 FOXO6; forkhead box protein O6
K04603 GRM1; metabotropic glutamate receptor 1
K15010 HOMER; homer
K17848 AGAP2; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K05405 IL6; interleukin 6
K05443 IL10, CSIF; interleukin 10
K04692 STAT3; signal transducer and activator of transcription 3
K04357 EGF; epidermal growth factor
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K11434 PRMT1; type I protein arginine methyltransferase [EC:2.1.1.319]
K09385 FOXG; forkhead box protein G
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10146 CCNG2; cyclin G2
K04685 CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
K06623 CDKN2D, P19, INK4D; cyclin-dependent kinase inhibitor 2D
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K16332 RBL2; retinoblastoma-like protein 2
K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
K08861 PLK2; polo-like kinase 2 [EC:2.7.11.21]
K08862 PLK3, CNK; polo-like kinase 3 [EC:2.7.11.21]
K08863 PLK4; polo-like kinase 4 [EC:2.7.11.21]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K16341 BCL2L11, BIM; Bcl-2-like protein 11
K04721 TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
K15618 BCL6; B-cell lymphoma 6 protein
K15464 BNIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
K08336 ATG12; ubiquitin-like protein ATG12
K08341 GABARAP, ATG8, LC3; GABA(A) receptor-associated protein
K03781 katE, CAT, catB, srpA; catalase [EC:1.11.1.6]
K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
K04728 ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]
K01596 E4.1.1.32, pckA, PCK; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K05072 IL7R, CD127; interleukin 7 receptor
K17845 KLF2; krueppel-like factor 2
K04288 S1PR1, EDG1, CD363; sphingosine 1-phosphate receptor 1
K04293 S1PR4, EDG6; sphingosine 1-phosphate receptor 4
K10628 RAG1; V(D)J recombination-activating protein 1 [EC:2.3.2.27]
K10988 RAG2; recombination-activating protein 2
K10305 FBXO25_32; F-box protein 25/32
|
04020 Calcium signaling pathway [PATH:ko04020]
|
04070 Phosphatidylinositol signaling system [PATH:ko04070]
|
K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
K19801 PI4KB; phosphatidylinositol 4-kinase B [EC:2.7.1.67]
K13711 PI4K2; phosphatidylinositol 4-kinase type 2 [EC:2.7.1.67]
K21797 SAC1, SACM1L; phosphatidylinositol 4-phosphatase [EC:3.1.3.-]
K21798 SAC2, INPP5F; phosphatidylinositol 4-phosphatase [EC:3.1.3.-]
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
K20278 INPP5E; inositol polyphosphate 5-phosphatase INPP5E [EC:3.1.3.36]
K20279 SYNJ; synaptojanin [EC:3.1.3.36]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K03084 SHIP1, INPP5D; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 [EC:3.1.3.86]
K15909 SHIP2, INPPL1; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 [EC:3.1.3.86]
K01109 INPP4; inositol polyphosphate-4-phosphatase [EC:3.1.3.66]
K00921 PIKFYVE, FAB1; 1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150]
K01108 MTM1; myotubularin [EC:3.1.3.64 3.1.3.95]
K18081 MTMR1_2; myotubularin-related protein 1/2 [EC:3.1.3.64 3.1.3.95]
K18082 MTMR3_4, ZFYVE10_11; myotubularin-related protein 3/4 [EC:3.1.3.48 3.1.3.64 3.1.3.95]
K18083 MTMR6_7_8; myotubularin-related protein 6/7/8 [EC:3.1.3.64 3.1.3.95]
K18086 MTMR14; myotubularin-related protein 14 [EC:3.1.3.64 3.1.3.95]
K00920 PIP4K2; 1-phosphatidylinositol-5-phosphate 4-kinase [EC:2.7.1.149]
K13084 TMEM55; phosphatidylinositol-4,5-bisphosphate 4-phosphatase [EC:3.1.3.78]
K00914 PIK3C3, VPS34; phosphatidylinositol 3-kinase [EC:2.7.1.137]
K00923 PIK3C2; phosphatidylinositol-4-phosphate 3-kinase [EC:2.7.1.154]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
K05860 PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K05861 PLCZ; phosphatidylinositol phospholipase C, zeta [EC:3.1.4.11]
K00915 IPMK, IPK2; inositol-polyphosphate multikinase [EC:2.7.1.140 2.7.1.151]
K00911 ITPK; 1D-myo-inositol-triphosphate 3-kinase [EC:2.7.1.127]
K01106 INPP5A; inositol polyphosphate 5-phosphatase INPP5A [EC:3.1.3.56]
K00913 ITPK1; inositol-1,3,4-trisphosphate 5/6-kinase / inositol-tetrakisphosphate 1-kinase [EC:2.7.1.159 2.7.1.134]
K10572 IPPK; inositol-pentakisphosphate 2-kinase [EC:2.7.1.158]
K19786 IPK1; inositol-pentakisphosphate 2-kinase [EC:2.7.1.158]
K07756 IP6K, IHPK; inositol-hexakisphosphate 5-kinase [EC:2.7.4.21]
K13024 PPIP5K, VIP; inositol-hexakisphosphate/diphosphoinositol-pentakisphosphate 1-kinase [EC:2.7.4.24]
K01107 INPP1; inositol polyphosphate 1-phosphatase [EC:3.1.3.57]
K15422 SAL; 3'(2'), 5'-bisphosphate nucleotidase / inositol polyphosphate 1-phosphatase [EC:3.1.3.7 3.1.3.57]
K01092 E3.1.3.25, IMPA, suhB; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
K10047 VTC4; inositol-phosphate phosphatase / L-galactose 1-phosphate phosphatase [EC:3.1.3.25 3.1.3.93]
K18649 IMPL2; inositol-phosphate phosphatase / L-galactose 1-phosphate phosphatase / histidinol-phosphatase [EC:3.1.3.25 3.1.3.93 3.1.3.15]
K15759 IMPAD1, IMPA3; Golgi-resident PAP phosphatase [EC:3.1.3.7]
K00901 dgkA, DGK; diacylglycerol kinase (ATP) [EC:2.7.1.107]
K00981 E2.7.7.41, CDS1, CDS2, cdsA; phosphatidate cytidylyltransferase [EC:2.7.7.41]
K00999 CDIPT; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [EC:2.7.8.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K02183 CALM; calmodulin
|
04072 Phospholipase D signaling pathway [PATH:ko04072]
|
04071 Sphingolipid signaling pathway [PATH:ko04071]
|
K00654 SPT; serine palmitoyltransferase [EC:2.3.1.50]
K26384 SPTSS; serine palmitoyltransferase small subunit
K04710 CERS1, LASS1; sphingoid base N-stearoyltransferase [EC:2.3.1.299]
K24621 CERS2_4, LASS2_4; very-long-chain ceramide synthase [EC:2.3.1.297]
K24622 CERS3, LASS3; very-long-chain ceramide synthase / ultra-long-chain ceramide synthase [EC:2.3.1.297 2.3.1.298]
K23727 CERS5_6, LASS5_6; sphingoid base N-palmitoyltransferase [EC:2.3.1.291]
K04712 DEGS; sphingolipid 4-desaturase/C4-monooxygenase [EC:1.14.19.17 1.14.18.5]
K12350 SMPD1, ASM; sphingomyelin phosphodiesterase [EC:3.1.4.12]
K04714 SGMS; shingomyelin synthase [EC:2.7.8.27]
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K18953 NSMAF, FAN; factor associated with neutral sphingomyelinase activation
K12351 SMPD2; sphingomyelin phosphodiesterase 2 [EC:3.1.4.12]
K12348 ASAH1; acid ceramidase [EC:3.5.1.23]
K12349 ASAH2; neutral ceramidase [EC:3.5.1.23]
K01441 ACER1_2, ASAH3; alkaline ceramidase [EC:3.5.1.23]
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K01379 CTSD; cathepsin D [EC:3.4.23.5]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02161 BCL2; apoptosis regulator Bcl-2
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K04451 TP53, P53; tumor protein p53
K08089 FCER1A; high affinity immunoglobulin epsilon receptor subunit alpha
K08090 MS4A2, FCER1B; high affinity immunoglobulin epsilon receptor subunit beta
K07983 FCER1G; high affinity immunoglobulin epsilon receptor subunit gamma
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K08091 GAB2; GRB2-associated-binding protein 2
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K03898 KNG, BK; kininogen
K04265 ADORA1; adenosine receptor A1
K04268 ADORA3; adenosine receptor A3
K03916 BDKRB2; bradykinin receptor B2
K04213 OPRD1; delta-type opioid receptor
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04716 SGPP1; sphingosine-1-phosphate phosphatase 1 [EC:3.1.3.-]
K04717 SGPP2; sphingosine-1-phosphate phosphotase 2 [EC:3.1.3.-]
K05665 ABCC1; ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3]
K01634 SGPL1, DPL1; sphinganine-1-phosphate aldolase [EC:4.1.2.27]
K04288 S1PR1, EDG1, CD363; sphingosine 1-phosphate receptor 1
K04292 S1PR2, EDG5; sphingosine 1-phosphate receptor 2
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04290 S1PR3, EDG3; sphingosine 1-phosphate receptor 3
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04293 S1PR4, EDG6; sphingosine 1-phosphate receptor 4
K04295 S1PR5, EDG8; sphingosine 1-phosphate receptor 5
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
|
04024 cAMP signaling pathway [PATH:ko04024]
|
04022 cGMP-PKG signaling pathway [PATH:ko04022]
|
04151 PI3K-Akt signaling pathway [PATH:ko04151]
|
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K09784 EREG; epiregulin
K09782 AREG; amphiregulin
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K05451 NGFA; nerve growth factor, alpha
K02582 NGFB; nerve growth factor, beta
K04355 BDNF; brain-derived neurotrophic factor
K04356 NTF3; neurotrophin 3
K12457 NTF4; neurotrophin 4
K04526 INS; insulin
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K05461 KITLG; KIT ligand
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05460 HGF; hepatocyte growth factor
K05465 ANGPT1; angiopoietin 1
K05466 ANGPT2; angiopoietin 2
K05467 ANGPT4; angiopoietin 4
K05462 EFNA; ephrin-A
K05452 GDNF; glial cell derived neurotrophic factor
K25414 NRTN; neurturin
K25415 ARTN; artemin
K25416 PSPN; persephin
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05084 ERBB3, HER3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K05085 ERBB4, HER4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K02583 NGFR, TNFRSF16, CD271; tumor necrosis factor receptor superfamily member 16
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K04360 NTRK2, TRKB; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05090 CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K05091 KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05092 FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05096 FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05097 FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K05098 KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05121 TEK, TIE2, CD202; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
K05103 EPHA2, ECK; Eph receptor A2 [EC:2.7.10.1]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K16172 IRS1; insulin receptor substrate 1
K10159 TLR2, CD282; toll-like receptor 2
K10160 TLR4, CD284; toll-like receptor 4
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K06856 IGH; immunoglobulin heavy chain
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K06465 CD19; B-lymphocyte antigen CD19
K12230 PIK3AP1, BCAP; phosphoinositide 3-kinase adapter protein 1
K05438 GH; growth hormone
K05439 PRL; prolactin
K05418 OSM; oncostatin M
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05405 IL6; interleukin 6
K05430 IL4; interleukin 4
K05431 IL7; interleukin 7
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05437 EPO; erythropoietin
K05423 CSF3, GCSF; granulocyte colony-stimulating factor
K05080 GHR; growth hormone receptor
K05081 PRLR; prolactin receptor
K05057 OSMR; oncostatin M receptor
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05069 IL2RB, CD122; interleukin 2 receptor beta
K05070 IL2RG, CD132; interleukin 2 receptor gamma
K04737 IL3RA, CD123; interleukin 3 receptor alpha
K05055 IL6R, CD126; interleukin 6 receptor
K05071 IL4R, CD124; interleukin 4 receptor
K05072 IL7R, CD127; interleukin 7 receptor
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05079 EPOR; erythropoietin receptor
K05061 CSF3R, CD114; granulocyte colony-stimulating factor receptor
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K06236 COL1A; collagen type I alpha
K19719 COL2A; collagen type II alpha
K06237 COL4A; collagen type IV alpha
K06238 COL6A; collagen type VI alpha
K08131 COL9A; collagen type IX alpha
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K06248 CHAD; chondroadherin
K06249 RELN; reelin [EC:3.4.21.-]
K16857 THBS1; thrombospondin 1
K04659 THBS2S; thrombospondin 2/3/4/5
K05717 FN1; fibronectin 1
K06250 SPP1, BNSP, OPN; secreted phosphoprotein 1
K06251 VTN; vitronectin
K06252 TN; tenascin
K03900 VWF; von Willebrand factor
K06253 IBSP; integrin binding sialoprotein
K06480 ITGA1, CD49a; integrin alpha 1
K06481 ITGA2, CD49b; integrin alpha 2
K06476 ITGA2B, CD41; integrin alpha 2B
K06482 ITGA3, CD49c; integrin alpha 3
K06483 ITGA4, CD49d; integrin alpha 4
K06484 ITGA5, CD49e; integrin alpha 5
K06485 ITGA6, CD49f; integrin alpha 6
K06583 ITGA7; integrin alpha 7
K06584 ITGA8; integrin alpha 8
K06585 ITGA9; integrin alpha 9
K06586 ITGA10; integrin alpha 10
K06587 ITGA11; integrin alpha 11
K06487 ITGAV, CD51; integrin alpha V
K05719 ITGB1, CD29; integrin beta 1
K06493 ITGB3, CD61; integrin beta 3
K06525 ITGB4, CD104; integrin beta 4
K06588 ITGB5; integrin beta 5
K06589 ITGB6; integrin beta 6
K06590 ITGB7; integrin beta 7
K06591 ITGB8; integrin beta 8
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K03914 F2R, PAR1; coagulation factor II (thrombin) receptor
K04129 CHRM1; muscarinic acetylcholine receptor M1
K04130 CHRM2; muscarinic acetylcholine receptor M2
K04289 LPAR1, EDG2; lysophosphatidic acid receptor 1
K04291 LPAR2, EDG4; lysophosphatidic acid receptor 2
K04294 LPAR3, EDG7; lysophosphatidic acid receptor 3
K04275 LPAR4, GPR23; lysophosphatidic acid receptor 4
K08390 LPAR5, GPR92; lysophosphatidic acid receptor 5
K04273 LPAR6, P2RY5; lysophosphatidic acid receptor 6
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K21289 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K07298 STK11, LKB1; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K07198 PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K08270 DDIT4, REDD1; DNA-damage-inducible transcript 4
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K08266 MLST8, GBL; target of rapamycin complex subunit LST8
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07204 RAPTOR; regulatory associated protein of mTOR
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K03259 EIF4E; translation initiation factor 4E
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K03258 EIF4B; translation initiation factor 4B
K02991 RP-S6e, RPS6; small subunit ribosomal protein S6e
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K06071 PKN1; serine/threonine-protein kinase N1 [EC:2.7.11.13]
K23691 PKN2; serine/threonine-protein kinase N2 [EC:2.7.11.13]
K23692 PKN3; serine/threonine-protein kinase N3 [EC:2.7.11.13]
K13302 SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
K13303 SGK2; serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
K13304 SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K05631 AIP3, WWP3, BAIAP1; atrophin-1 interacting protein 3 (BAI1-associated protein 1)
K05629 AIP1; atrophin-1 interacting protein 1
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K16339 THEM4, CTMP; acyl-coenzyme A thioesterase THEM4 [EC:3.1.2.2]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K04079 HSP90A, htpG; molecular chaperone HtpG
K09487 HSP90B, TRA1; heat shock protein 90kDa beta
K09554 CDC37; cell division cycle protein 37
K16333 CRTC2, TORC2; CREB-regulated transcription coactivator 2
K16340 PHLPP; PH domain and leucine-rich repeat-containing protein phosphatase [EC:3.1.3.16]
K10167 TCL1A; T-cell leukemia/lymphoma 1A
K16836 TCL1B; T-cell leukemia/lymphoma 1B
K16837 MTCP1; mature T-cell proliferation-1 type B1
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K01596 E4.1.1.32, pckA, PCK; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K06626 CCNE; G1/S-specific cyclin-E1
K09408 FOXO3; forkhead box protein O3
K16332 RBL2; retinoblastoma-like protein 2
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K16341 BCL2L11, BIM; Bcl-2-like protein 11
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K06630 YWHAE; 14-3-3 protein epsilon
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K02539 MCL1; myeloid leukemia cell differntiation protein MCL-1
K08524 RXRA, NR2B1; retinoid X receptor alpha
K04465 NR4A1, HMR; nuclear receptor subfamily 4 group A member 1
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K09420 MYB, C-MYB; transcriptional activator Myb
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53, P53; tumor protein p53
|
04152 AMPK signaling pathway [PATH:ko04152]
|
04150 mTOR signaling pathway [PATH:ko04150]
|
K13780 SLC7A5, LAT1; solute carrier family 7 (L-type amino acid transporter), member 5
K06519 SLC3A2, MDU1, CD98; solute carrier family 3, member 2
K14995 SLC38A9; solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 9
K02145 ATPeV1A, ATP6A; V-type H+-transporting ATPase subunit A [EC:7.1.2.2]
K02147 ATPeV1B, ATP6B; V-type H+-transporting ATPase subunit B
K02148 ATPeV1C, ATP6C; V-type H+-transporting ATPase subunit C
K02149 ATPeV1D, ATP6M; V-type H+-transporting ATPase subunit D
K02150 ATPeV1E, ATP6E; V-type H+-transporting ATPase subunit E
K02151 ATPeV1F, ATP6S14; V-type H+-transporting ATPase subunit F
K02152 ATPeV1G, ATP6G; V-type H+-transporting ATPase subunit G
K02144 ATPeV1H; V-type H+-transporting ATPase subunit H
K20397 LAMTOR1; ragulator complex protein LAMTOR1
K20398 LAMTOR2; ragulator complex protein LAMTOR2
K04370 LAMTOR3, MP1, MAP2K1IP1; ragulator complex protein LAMTOR3
K20399 LAMTOR4; ragulator complex protein LAMTOR4
K16344 LAMTOR5, HBXIP; ragulator complex protein LAMTOR5
K09594 FLCN, BHD; folliculin
K20400 FNIP1; folliculin-interacting protein 1
K20401 FNIP2; folliculin-interacting protein 2
K16185 RRAGA_B; Ras-related GTP-binding protein A/B
K16186 RRAGC_D; Ras-related GTP-binding protein C/D
K20394 SESN2; sestrin 2
K23080 CASTOR1; cytosolic arginine sensor for mTORC1 subunit 1
K23081 CASTOR2; cytosolic arginine sensor for mTORC1 subunit 2
K20407 MIOS, MIO, SEA4; SEA/GATOR complex protein SEA4/MIOS
K14299 SEH1; nucleoporin SEH1
K20408 WDR24, SEA2; SEA/GATOR complex protein SEA2/WDR24
K20409 WDR59, SEA3; SEA/GATOR complex protein SEA3/WDR59
K14004 SEC13; protein transport protein SEC13
K20404 DEPDC5, SEA1; SEA/GATOR complex protein SEA1/DEPDC5
K20405 NPRL2, NPR2; nitrogen permease regulator 2
K20406 NPRL3, NPR3; nitrogen permease regulator 3
K03875 SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K15705 RNF152; E3 ubiquitin-protein ligase RNF152 [EC:2.3.2.27]
K07204 RAPTOR; regulatory associated protein of mTOR
K16184 AKT1S1, PRAS40; proline-rich AKT1 substrate 1
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K20402 DEPTOR; DEP domain-containing mTOR-interacting protein
K08266 MLST8, GBL; target of rapamycin complex subunit LST8
K11137 TELO2, TEL2; telomere length regulation protein
K20403 TTI1; TELO2-interacting protein 1
K10421 CLIP1, RSN; CAP-Gly domain-containing linker protein 1
K20064 GRB10; growth factor receptor-bound protein 10
K15728 LPIN; phosphatidate phosphatase LPIN [EC:3.1.3.4]
K21357 ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
K08269 ULK2, ATG1; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K03259 EIF4E; translation initiation factor 4E
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K03258 EIF4B; translation initiation factor 4B
K02991 RP-S6e, RPS6; small subunit ribosomal protein S6e
K08271 STRADA, LYK5; STE20-related kinase adapter protein alpha
K17532 STRADB; STE20-related kinase adapter protein beta
K07298 STK11, LKB1; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K08272 CAB39, MO25; calcium binding protein 39
K07198 PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K20396 TBC1D7; TBC1 domain family member 7
K07208 RHEB; Ras homolog enriched in brain
K08270 DDIT4, REDD1; DNA-damage-inducible transcript 4
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7, fz; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4, fz4, CD344; frizzled 4
K02375 FZD5_8, fz2; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10, CD349_50; frizzled 9/10
K04690 FZDN, fz3; frizzled
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04526 INS; insulin
K05459 IGF1; insulin-like growth factor 1
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K16172 IRS1; insulin receptor substrate 1
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K20410 MAPKAP1, SIN1, AVO1; target of rapamycin complex 2 subunit MAPKAP1/AVO1
K08267 RICTOR; rapamycin-insensitive companion of mTOR
K20411 PRR5, PROTOR; proline-rich protein 5
K04513 RHOA; Ras homolog gene family, member A
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K13302 SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
|
04075 Plant hormone signal transduction [PATH:ko04075]
|
|
09133 Signaling molecules and interaction
|
|
09140 Cellular Processes
|
|
09141 Transport and catabolism
|
04144 Endocytosis [PATH:ko04144]
|
04145 Phagosome [PATH:ko04145]
|
04142 Lysosome [PATH:ko04142]
|
04146 Peroxisome [PATH:ko04146]
|
04140 Autophagy - animal [PATH:ko04140]
|
K04526 INS; insulin
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K17445 IRS3; insulin receptor substrate 3
K17446 IRS4; insulin receptor substrate 4
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K07831 MRAS; Ras-related protein M-Ras
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2, TC21; Ras-related protein R-Ras2
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K08270 DDIT4, REDD1; DNA-damage-inducible transcript 4
K07207 TSC2; tuberous sclerosis 2
K07206 TSC1; tuberous sclerosis 1
K15464 BNIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
K07208 RHEB; Ras homolog enriched in brain
K07204 RAPTOR; regulatory associated protein of mTOR
K20402 DEPTOR; DEP domain-containing mTOR-interacting protein
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K16184 AKT1S1, PRAS40; proline-rich AKT1 substrate 1
K08266 MLST8, GBL; target of rapamycin complex subunit LST8
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K17606 IGBP1, TAP42; immunoglobulin-binding protein 1
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K21357 ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
K08269 ULK2, ATG1; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
K08331 ATG13; autophagy-related protein 13
K19730 ATG101; autophagy-related protein 101
K17589 RB1CC1; RB1-inducible coiled-coil protein 1
K17906 ATG2; autophagy-related protein 2
K17908 WIPI1_2, ATG18; autophagy-related protein 18
K22991 WDR45, WIPI4, WIPI3; WD repeat-containing protein 45
K17907 ATG9; autophagy-related protein 9
K21245 SUPT20H; transcription factor SPT20 homolog
K23611 SMCR8; guanine nucleotide exchange protein SMCR8
K23610 WDR41; WD repeat-containing protein 41
K23609 C9ORF72; guanine nucleotide exchange protein C9orf72
K07901 RAB8A, MEL; Ras-related protein Rab-8A
K07925 RAB39B; Ras-related protein Rab-39B
K14381 SQSTM1; sequestosome 1
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K12650 TANK; TRAF family member-associated NF-kappa-B activator
K07874 RAB1A; Ras-related protein Rab-1A
K16185 RRAGA_B; Ras-related GTP-binding protein A/B
K16186 RRAGC_D; Ras-related GTP-binding protein C/D
K07298 STK11, LKB1; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K07198 PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K02161 BCL2; apoptosis regulator Bcl-2
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02158 BAD; Bcl-2-antagonist of cell death
K08334 BECN, VPS30, ATG6; beclin
K21246 NRBF2; nuclear receptor-binding factor 2
K08333 PIK3R4, VPS15; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
K00914 PIK3C3, VPS34; phosphatidylinositol 3-kinase [EC:2.7.1.137]
K17889 ATG14L, ATG14; beclin 1-associated autophagy-related key regulator
K17985 AMBRA1; activating molecule in BECN1-regulated autophagy protein 1
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K21247 TP53INP2; tumor protein p53-inducible nuclear protein 2
K21248 VMP1; vacuole membrane protein 1
K08491 STX17; syntaxin 17
K21249 UVRAG; UV radiation resistance-associated gene protein
K11248 SH3GLB1; endophilin-B1
K19330 RUBCN; run domain Beclin-1 interacting and cysteine-rich containing protein
K07359 CAMKK2; calcium/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K08852 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K10802 HMGB1; high mobility group protein B1
K21250 PRAP1; proline-rich acidic protein 1
K08860 EIF2AK3, PERK; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K16196 EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]
K03237 EIF2S1; translation initiation factor 2 subunit 1
K18082 MTMR3_4, ZFYVE10_11; myotubularin-related protein 3/4 [EC:3.1.3.48 3.1.3.64 3.1.3.95]
K18086 MTMR14; myotubularin-related protein 14 [EC:3.1.3.64 3.1.3.95]
K17603 ZFYVE1; zinc finger FYVE domain-containing protein 1
K08336 ATG12; ubiquitin-like protein ATG12
K08339 ATG5; autophagy-related protein 5
K17890 ATG16L1; autophagy-related protein 16-1
K20868 ATG16L2; autophagy-related protein 16-2
K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
K17888 ATG10L, ATG10; ubiquitin-like-conjugating enzyme ATG10
K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
K04724 CFLAR, FLIP; CASP8 and FADD-like apoptosis regulator
K07920 RAB33B; Ras-related protein Rab-33B
K18052 PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
K08341 GABARAP, ATG8, LC3; GABA(A) receptor-associated protein
K10435 MAP1LC; microtubule-associated protein 1 light chain
K08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]
K17987 NBR1; next to BRCA1 gene 1 protein
K19946 OPTN, FIP2; optineurin
K21348 CALCOCO2, NDP52; calcium-binding and coiled-coil domain-containing protein 2
K21347 TAX1BP1; Tax1-binding protein 1
K22262 WDFY3, ALFY; WD repeat and FYVE domain-containing protein 3
K02927 RP-L40e, RPL40, UBA52; ubiquitin-large subunit ribosomal protein L40e
K02977 RP-S27Ae, RPS27A, UBA80; ubiquitin-small subunit ribosomal protein S27Ae
K04551 UBB; ubiquitin B
K08770 UBC; ubiquitin C
K08509 SNAP29; synaptosomal-associated protein 29
K08512 VAMP8; vesicle-associated membrane protein 8
K08516 YKT6; synaptobrevin homolog YKT6
K08488 STX7; syntaxin 7
K23883 EPG5; ectopic P granules protein 5
K23282 PLEKHM1; pleckstrin homology domain-containing family M member 1
K20179 VPS11, PEP5; vacuolar protein sorting-associated protein 11
K20180 VPS16; vacuolar protein sorting-associated protein 16
K20181 VPS18, PEP3; vacuolar protein sorting-associated protein 18
K20182 VPS33A; vacuolar protein sorting-associated protein 33A
K20183 VPS39, VAM6; Vam6/Vps39-like protein vacuolar protein sorting-associated protein 39
K20184 VPS41; vacuolar protein sorting-associated protein 41
K10586 BIRC6, BRUCE; baculoviral IAP repeat-containing protein 6 (apollon) [EC:2.3.2.23]
K26797 GORASP, GRASP65_55; golgi reassembly-stacking protein
K07897 RAB7A; Ras-related protein Rab-7A
K07898 RAB7B; Ras-related protein Rab-7B
K06528 LAMP1_2, CD107; lysosomal-associated membrane protein 1/2
K01379 CTSD; cathepsin D [EC:3.4.23.5]
K01365 CTSL; cathepsin L [EC:3.4.22.15]
K01363 CTSB; cathepsin B [EC:3.4.22.1]
|
04138 Autophagy - yeast [PATH:ko04138]
|
04136 Autophagy - other [PATH:ko04136]
|
04137 Mitophagy - animal [PATH:ko04137]
|
04139 Mitophagy - yeast [PATH:ko04139]
|
04148 Efferocytosis [PATH:ko04148]
|
|
09143 Cell growth and death
|
04110 Cell cycle [PATH:ko04110]
|
04111 Cell cycle - yeast [PATH:ko04111]
|
04112 Cell cycle - Caulobacter [PATH:ko04112]
|
04113 Meiosis - yeast [PATH:ko04113]
|
04114 Oocyte meiosis [PATH:ko04114]
|
04210 Apoptosis [PATH:ko04210]
|
04214 Apoptosis - fly [PATH:ko04214]
|
04215 Apoptosis - multiple species [PATH:ko04215]
|
04216 Ferroptosis [PATH:ko04216]
|
04217 Necroptosis [PATH:ko04217]
|
04115 p53 signaling pathway [PATH:ko04115]
|
K04728 ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K19748 GORAB, SCYL1BP1; RAB6-interacting golgin
K06621 CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K10127 MDM4, MDMX; protein Mdm4
K04451 TP53, P53; tumor protein p53
K27356 PPP1R13L; RelA-associated inhibitor
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06644 SFN; stratifin
K10128 RPRM; reprimo, TP53-dependent G2 arrest mediator candidate
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K02087 CDK1, CDC2; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K10129 GTSE1, B99; G-2 and S-phase expressed protein 1
K26543 ZNF385A, HZF; zinc finger protein 385A
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K10130 LRDD, PIDD; leucine-rich repeats and death domain-containing protein
K04722 TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K10131 PMAIP1, NOXA; phorbol-12-myristate-13-acetate-induced protein 1
K10132 BBC3, PUMA; Bcl-2-binding component 3
K13773 TP53AIP1; p53-regulated apoptosis-inducing protein 1
K22744 SIVA1; apoptosis regulatory protein Siva
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K10133 TP53I3; tumor protein p53-inducible protein 3 [EC:1.-.-.-]
K10134 EI24; etoposide-induced 2.4 mRNA
K10135 SCOTIN; scotin
K10136 PERP; TP53 apoptosis effector
K10137 ZMAT3; zinc finger, matrin type 3
K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K22745 AIFM2; apoptosis-inducing factor 2
K10138 IGFBP3; insulin-like growth factor-binding protein 3
K05459 IGF1; insulin-like growth factor 1
K03982 SERPINE1, PAI1; plasminogen activator inhibitor 1
K04596 ADGRB1, BAI1; adhesion G protein-coupled receptor B1
K06509 KAI1, CD82, TSPAN27; CD82 antigen
K16857 THBS1; thrombospondin 1
K10139 SERPINB5; serpin B5
K10140 DDB2; DNA damage-binding protein 2
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K10141 SESN1_3; sestrin 1/3
K20394 SESN2; sestrin 2
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K07207 TSC2; tuberous sclerosis 2
K10142 STEAP3, TSAP6; metalloreductase STEAP3 [EC:1.16.1.-]
K10143 RFWD2, COP1; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]
K10144 RCHY1, PIRH2; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
K10145 CCNG1; cyclin G1
K10146 CCNG2; cyclin G2
K10147 PPM1D, WIP1; protein phosphatase 1D [EC:3.1.3.16]
K10148 TP73; tumor protein p73
|
04218 Cellular senescence [PATH:ko04218]
|
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04685 CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K06618 RB1; retinoblastoma-associated protein
K04681 RBL1; retinoblastoma-like protein 1
K16332 RBL2; retinoblastoma-like protein 2
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04682 E2F4_5; transcription factor E2F4/5
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06751 MHC1; MHC class I antigen
K24231 KIR2DL4, CD158D; killer cell immunoglobulin-like receptor 2DL4
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2, TC21; Ras-related protein R-Ras2
K07831 MRAS; Ras-related protein M-Ras
K02833 HRAS; GTPase HRas
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K11411 SIRT1, SIR2L1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K06627 CCNA; cyclin-A
K21769 MYBL2, B-MYB; myb-related protein B
K21773 LIN9; protein lin-9
K21774 LIN37; protein lin-37
K21775 LIN52; protein lin-52
K21776 LIN54; protein lin-54
K10752 RBBP4, HAT2, CAF1, MIS16; histone-binding protein RBBP4
K09406 FOXM; forkhead box protein M
K04377 MYC; Myc proto-oncogene protein
K06621 CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53, P53; tumor protein p53
K08015 RASSF5, RAPL; Ras association domain-containing protein 5
K03362 FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K02678 ETS1, pnt; C-ets-1
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02087 CDK1, CDC2; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K10865 MRE11; double-strand break repair protein MRE11
K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
K10867 NBN, NBS1; nibrin
K04728 ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
K10995 RAD9B; cell cycle checkpoint control protein RAD9B
K02830 HRAD1, RAD17; cell cycle checkpoint protein [EC:3.1.11.2]
K10903 HUS1; HUS1 checkpoint protein
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
K14381 SQSTM1; sequestosome 1
K09183 GATA4; GATA-binding protein 4
K21124 TRAF3IP2, ACT1; adaptor protein CIKS
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04383 IL1A; interleukin 1 alpha
K05405 IL6; interleukin 6
K10030 IL8, CXCL8; interleukin 8
K10138 IGFBP3; insulin-like growth factor-binding protein 3
K03982 SERPINE1, PAI1; plasminogen activator inhibitor 1
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K18753 ZFP36L; butyrate response factor
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
K04973 TRPV4; transient receptor potential cation channel subfamily V member 4
K04982 TRPM7, CHAK1; transient receptor potential cation channel subfamily M member 7 [EC:2.7.11.1]
K01367 CAPN1; calpain-1 [EC:3.4.22.52]
K03853 CAPN2; calpain-2 [EC:3.4.22.53]
K02183 CALM; calmodulin
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K05863 SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05864 PPID, CYPD; peptidyl-prolyl isomerase D [EC:5.2.1.8]
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K20858 MCU; calcium uniporter protein, mitochondrial
|
|
09144 Cellular community - eukaryotes
|
04510 Focal adhesion [PATH:ko04510]
|
K06236 COL1A; collagen type I alpha
K19719 COL2A; collagen type II alpha
K06237 COL4A; collagen type IV alpha
K06238 COL6A; collagen type VI alpha
K08131 COL9A; collagen type IX alpha
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K06248 CHAD; chondroadherin
K06249 RELN; reelin [EC:3.4.21.-]
K16857 THBS1; thrombospondin 1
K04659 THBS2S; thrombospondin 2/3/4/5
K05717 FN1; fibronectin 1
K06250 SPP1, BNSP, OPN; secreted phosphoprotein 1
K06251 VTN; vitronectin
K06252 TN; tenascin
K03900 VWF; von Willebrand factor
K06253 IBSP; integrin binding sialoprotein
K06480 ITGA1, CD49a; integrin alpha 1
K06481 ITGA2, CD49b; integrin alpha 2
K06476 ITGA2B, CD41; integrin alpha 2B
K06482 ITGA3, CD49c; integrin alpha 3
K06483 ITGA4, CD49d; integrin alpha 4
K06484 ITGA5, CD49e; integrin alpha 5
K06485 ITGA6, CD49f; integrin alpha 6
K06583 ITGA7; integrin alpha 7
K06584 ITGA8; integrin alpha 8
K06585 ITGA9; integrin alpha 9
K06586 ITGA10; integrin alpha 10
K06587 ITGA11; integrin alpha 11
K06487 ITGAV, CD51; integrin alpha V
K05719 ITGB1, CD29; integrin beta 1
K06493 ITGB3, CD61; integrin beta 3
K06525 ITGB4, CD104; integrin beta 4
K06588 ITGB5; integrin beta 5
K06589 ITGB6; integrin beta 6
K06590 ITGB7; integrin beta 7
K06591 ITGB8; integrin beta 8
K26256 EMP2; epithelial membrane protein 2
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K04357 EGF; epidermal growth factor
K05459 IGF1; insulin-like growth factor 1
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05460 HGF; hepatocyte growth factor
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K05098 KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05096 FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05097 FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K26255 EMP1; epithelial membrane protein 1
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05732 ARHGAP35, GRLF1; glucocorticoid receptor DNA-binding factor 1
K13709 ARHGAP5; Rho GTPase-activating protein 5
K04513 RHOA; Ras homolog gene family, member A
K05740 DIAPH1; diaphanous 1
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10351 MYL2; myosin regulatory light chain 2
K12753 MYL5; myosin regulatory light chain 5
K12754 MYL7; myosin regulatory light chain 7
K12755 MYL9; myosin regulatory light chain 9
K12756 MYL10; myosin regulatory light chain 10
K12757 MYL12; myosin regulatory light chain 12
K12758 MYLPF; fast skeletal myosin light chain 2
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06270 PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
K12329 PPP1R12B, MYPT2; protein phosphatase 1 regulatory subunit 12B
K17457 PPP1R12C, MBS85; protein phosphatase 1 regulatory subunit 12C
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K05692 ACTB_G1; actin beta/gamma 1
K04349 RASGRF1; Ras-specific guanine nucleotide-releasing factor 1
K03853 CAPN2; calpain-2 [EC:3.4.22.53]
K05699 ACTN1_4; actinin alpha 1/4
K06271 TLN; talin
K04437 FLNA; filamin-A
K27392 FLNB; filamin-B
K05760 PXN; paxillin
K06272 ILK; integrin-linked kinase [EC:2.7.11.1]
K06273 ZYX; zyxin
K06274 VASP; vasodilator-stimulated phosphoprotein
K05700 VCL; vinculin
K06275 PARV; parvin
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02105 CTNNB1; catenin beta 1
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K05730 VAV; guanine nucleotide exchange factor VAV
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3, MRX30; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5, PAK7; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K04393 CDC42; cell division control protein 42
K05726 BCAR1, CAS; breast cancer anti-estrogen resistance 1
K04438 CRK, CRKII; C-crk adapter molecule crk
K13708 DOCK1; dedicator of cytokinesis protein 1
K06277 RAPGEF1, GRF2; Rap guanine nucleotide exchange factor 1
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K06278 CAV1; caveolin 1
K12958 CAV2; caveolin 2
K12959 CAV3; caveolin 3
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04375 ELK1; ETS domain-containing protein Elk-1
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K02158 BAD; Bcl-2-antagonist of cell death
K02161 BCL2; apoptosis regulator Bcl-2
|
04520 Adherens junction [PATH:ko04520]
|
04530 Tight junction [PATH:ko04530]
|
04540 Gap junction [PATH:ko04540]
|
04550 Signaling pathways regulating pluripotency of stem cells [PATH:ko04550]
|
|
09145 Cellular community - prokaryotes
|
|
09142 Cell motility
|
|
09150 Organismal Systems
|
|
09151 Immune system
|
|
09152 Endocrine system
|
|
09153 Circulatory system
|
|
09154 Digestive system
|
|
09155 Excretory system
|
|
09156 Nervous system
|
|
09157 Sensory system
|
|
09158 Development and regeneration
|
04320 Dorso-ventral axis formation [PATH:ko04320]
|
04360 Axon guidance [PATH:ko04360]
|
04361 Axon regeneration [PATH:ko04361]
|
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K20105 CED-4; cell death protein 4
K20106 CED-3; cell death protein 3
K10693 MYCBP2, PAM; RCR-type E3 ubiquitin transferase [EC:2.3.2.33]
K04422 MAP3K13, LZK; mitogen-activated protein kinase kinase kinase 13 [EC:2.7.11.25]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K09442 SPDEF; SAM pointed domain-containing ETS transcription factor
K23479 CCAAT/enhancer binding protein (C/EBP), other
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K12494 PSD; PH and SEC7 domain-containing protein
K10393 KIF2_24, MCAK; kinesin family member 2/24
K23439 AGBL4, CCP6; cytosolic carboxypeptidase protein 6 [EC:3.4.17.24]
K04459 DUSP, MKP; dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
K23489 SVH1, Teq; HGF/MSP/plasminogen-like protein
K04417 MAP3K9, MLK1; mitogen-activated protein kinase kinase kinase 9 [EC:2.7.11.25]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K09031 FOSLN; fos-like antigen, invertebrate
K15528 FAAH; fatty acid amide hydrolase [EC:3.5.1.99]
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K04163 HTR7; 5-hydroxytryptamine receptor 7
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K07532 ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
K04513 RHOA; Ras homolog gene family, member A
K00901 dgkA, DGK; diacylglycerol kinase (ATP) [EC:2.7.1.107]
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K00502 TPH1_2; tryptophan 5-monooxygenase [EC:1.14.16.4]
K01593 DDC, TDC; aromatic-L-amino-acid/L-tryptophan decarboxylase [EC:4.1.1.28 4.1.1.105]
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K09408 FOXO3; forkhead box protein O3
K16336 SDC2, CD362; syndecan 2
K06704 ADAM10, CD156c; disintegrin and metalloproteinase domain-containing protein 10 [EC:3.4.24.81]
K02599 NOTCH1; Notch 1
K04505 PSEN1, PS1; presenilin 1 [EC:3.4.23.-]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K07198 PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K06839 SLIT2; slit 2
K05110 EPHB1, ELK, NET; Eph receptor B1 [EC:2.7.10.1]
K06754 ROBO2; roundabout, axon guidance receptor 2
K06843 NTN1; netrin 1
K23487 EVL; Ena/VASP-like protein
K23488 RAPH1; Ras-associated and pleckstrin homology domains-containing protein 1
K19862 NCK2, GRB4; NCK adaptor protein 2
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K16980 MIRLET7; microRNA let-7
K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
K11593 ELF2C, AGO; eukaryotic translation initiation factor 2C
K23480 ZNF362_384, LIN-29; zinc finger protein 362/384
|
04380 Osteoclast differentiation [PATH:ko04380]
|
|
09149 Aging
|
04211 Longevity regulating pathway [PATH:ko04211]
|
04212 Longevity regulating pathway - worm [PATH:ko04212]
|
K19763 JKK1; dual specificity mitogen-activated protein kinase kinase JKK-1 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K19764 INS7; insulin-like neuropeptide
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K09408 FOXO3; forkhead box protein O3
K11411 SIRT1, SIR2L1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K27390 HCFC2; host cell factor 2
K17491 SMEK, PPP4R3; protein phosphatase 4 regulatory subunit 3
K14739 MT1_2; metallothionein 1/2
K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
K03781 katE, CAT, catB, srpA; catalase [EC:1.11.1.6]
K00799 GST, gst; glutathione S-transferase [EC:2.5.1.18]
K19765 HSBP1; heat shock factor-binding protein 1
K18463 CCDC53; WASH complex subunit CCDC53
K18461 WASH1; WAS protein family homolog 1
K09414 HSF1; heat shock transcription factor 1
K19766 HSP16.1; heat shock protein Hsp-16.1/Hsp-16.11
K19767 HSP16.49; heat shock protein Hsp-16.48/Hsp-16.49
K19768 HSP12.6; heat shock protein 12.6
K19769 SIP1; stress-induced protein 1
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K05638 NFE2L2, NRF2; nuclear factor erythroid 2-related factor 2
K11204 GCLC; glutamate--cysteine ligase catalytic subunit [EC:6.3.2.2]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K08035 FOXA2, HNF3B; forkhead box protein A2, hepatocyte nuclear factor 3-beta
K08269 ULK2, ATG1; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
K08341 GABARAP, ATG8, LC3; GABA(A) receptor-associated protein
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K19770 RNASEK; ribonuclease kappa [EC:3.1.-.-]
K12824 TCERG1, CA150; transcription elongation regulator 1
K17705 KRIT1, CCM1; Krev interaction trapped protein 1
K19771 LIPL4; lipase
K19772 LIPS17; triacylglycerol lipase
K14938 NVD, DAF36; cholesterol 7-desaturase [EC:1.14.19.21]
K22878 DAF9; cytochrome P450 daf-9 [EC:1.14.15.15]
K14035 NR1IN; nuclear receptor subfamily 1 group I
K13356 FAR; alcohol-forming fatty acyl-CoA reductase [EC:1.2.1.84]
K19773 NHR80; nuclear hormone receptor family member NHR-80
K00507 SCD, desC; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
K03871 VHL; von Hippel-Lindau disease tumor supressor
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
K01358 clpP, CLPP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
K19762 HAF1; ATP-binding cassette, subfamily B, HAIF transporter
K19774 DVE1; homeobox domain-containing protein
K13113 UBL5, HUB1; ubiquitin-like protein 5
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K17794 TIM23; mitochondrial import inner membrane translocase subunit TIM23
K04043 dnaK, HSPA9; molecular chaperone DnaK
K04077 groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7]
|
04213 Longevity regulating pathway - multiple species [PATH:ko04213]
|
|
09159 Environmental adaptation
|
|
09160 Human Diseases
|
|
09161 Cancer: overview
|
05200 Pathways in cancer [PATH:ko05200]
|
K06765 DCC; deleted in colorectal carcinoma
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K08733 APPL1, DIP13A; DCC-interacting protein 13 alpha
K05689 CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
K02105 CTNNB1; catenin beta 1
K05691 CTNNA; catenin alpha
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02620 TCF7, TCF-1; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7, fz; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4, fz4, CD344; frizzled 4
K02375 FZD5_8, fz2; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10, CD349_50; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
K09821 AGT, SERPINA8; angiotensinogen
K03914 F2R, PAR1; coagulation factor II (thrombin) receptor
K04236 F2RL3, PAR4; coagulation factor II (thrombin) receptor-like 3
K04289 LPAR1, EDG2; lysophosphatidic acid receptor 1
K04291 LPAR2, EDG4; lysophosphatidic acid receptor 2
K04294 LPAR3, EDG7; lysophosphatidic acid receptor 3
K04275 LPAR4, GPR23; lysophosphatidic acid receptor 4
K08390 LPAR5, GPR92; lysophosphatidic acid receptor 5
K04273 LPAR6, P2RY5; lysophosphatidic acid receptor 6
K04166 AGTR1; angiotensin II receptor type 1
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K07532 ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
K12331 ARHGEF11; Rho guanine nucleotide exchange factor 11
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K19464 PLEKHG5; pleckstrin homology domain-containing family G member 5
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4, CD184; C-X-C chemokine receptor type 4
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04258 PTGER1; prostaglandin E receptor 1
K04259 PTGER2; prostaglandin E receptor 2
K04260 PTGER3; prostaglandin E receptor 3
K04261 PTGER4; prostaglandin E receptor 4
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K06237 COL4A; collagen type IV alpha
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K05717 FN1; fibronectin 1
K06481 ITGA2, CD49b; integrin alpha 2
K06476 ITGA2B, CD41; integrin alpha 2B
K06482 ITGA3, CD49c; integrin alpha 3
K06485 ITGA6, CD49f; integrin alpha 6
K06487 ITGAV, CD51; integrin alpha V
K05719 ITGB1, CD29; integrin beta 1
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K09348 NKX3-1; homeobox protein Nkx-3.1
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K04735 RELA; transcription factor p65
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K02161 BCL2; apoptosis regulator Bcl-2
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K03172 TRAF1; TNF receptor-associated factor 1
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K03174 TRAF3; TNF receptor-associated factor 3
K09848 TRAF4; TNF receptor-associated factor 4
K09849 TRAF5; TNF receptor-associated factor 5
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K07201 FOXO1; forkhead box protein O1
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53, P53; tumor protein p53
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K08878 BCR1, BCR; breakpoint cluster region protein [EC:2.7.11.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K04438 CRK, CRKII; C-crk adapter molecule crk
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K08806 PIM2; proto-oncogene serine/threonine-protein kinase Pim-2 [EC:2.7.11.1]
K03898 KNG, BK; kininogen
K16366 EDN1; endothelin-1
K03915 BDKRB1; bradykinin receptor B1
K03916 BDKRB2; bradykinin receptor B2
K04197 EDNRA; endothelin receptor type A
K04198 EDNRB; endothelin receptor type B
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05405 IL6; interleukin 6
K05431 IL7; interleukin 7
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05435 IL13; interleukin 13
K05433 IL15; interleukin 15
K05426 IL23A; interleukin 23 subunit alpha
K05437 EPO; erythropoietin
K05414 IFNA; interferon alpha
K04687 IFNG; interferon gamma
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05069 IL2RB, CD122; interleukin 2 receptor beta
K05070 IL2RG, CD132; interleukin 2 receptor gamma
K04737 IL3RA, CD123; interleukin 3 receptor alpha
K05071 IL4R, CD124; interleukin 4 receptor
K04738 CSF2RB, IL3RB, CD131; cytokine receptor common subunit beta
K05067 IL5RA, CD125; interleukin 5 receptor alpha
K05055 IL6R, CD126; interleukin 6 receptor
K05060 IL6ST, GP130, CD130; interleukin 6 signal transducer
K05072 IL7R, CD127; interleukin 7 receptor
K05063 IL12RB1, CD212; interleukin 12 receptor beta-1
K05064 IL12RB2; interleukin 12 receptor beta-2
K05076 IL13RA1, CD213A1; interleukin 13 receptor alpha-1
K05074 IL15RA, CD215; interleukin 15 receptor alpha
K05065 IL23R; interleukin 23 receptor
K05079 EPOR; erythropoietin receptor
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K15420 EML4; echinoderm microtubule-associated protein-like 4
K05119 ALK, CD246; anaplastic lymphoma kinase [EC:2.7.10.1]
K04350 RASGRP1; RAS guanyl-releasing protein 1
K12361 RASGRP2; RAS guanyl-releasing protein 2
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12363 RASGRP4; RAS guanyl-releasing protein 4
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K11222 STAT4; signal transducer and activator of transcription 4
K11225 STAT6; signal transducer and activator of transcription 6
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K08774 TGFA; transforming growth factor, alpha
K04357 EGF; epidermal growth factor
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K05461 KITLG; KIT ligand
K05091 KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05092 FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05460 HGF; hepatocyte growth factor
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K02678 ETS1, pnt; C-ets-1
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K10030 IL8, CXCL8; interleukin 8
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K04445 RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K09288 CCDC6, PTC; coiled-coil domain-containing protein 6
K09289 NCOA4, PTC3; nuclear receptor coactivator 4
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K09290 TPM3; tropomyosin 3
K09291 TPR, MLP1, MLP2; nucleoprotein TPR
K09292 TFG; protein TFG
K09850 RASSF1; Ras association domain-containing protein 1
K08015 RASSF5, RAPL; Ras association domain-containing protein 5
K04411 STK4, MST1; serine/threonine kinase 4
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04375 ELK1; ETS domain-containing protein Elk-1
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K08773 RALBP1; RalA-binding protein 1
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K09293 PAX8; paired box protein 8
K08530 NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
K08524 RXRA, NR2B1; retinoid X receptor alpha
K08525 RXRB, NR2B2; retinoid X receptor beta
K08526 RXRG, NR2B3; retinoid X receptor gamma
K08528 RARB, NR1B2; retinoic acid receptor beta
K08550 ESR1, NR3A1; estrogen receptor alpha
K08551 ESR2, NR3A2; estrogen receptor beta
K09101 NCOA1, SRC1, KAT13A; nuclear receptor coactivator 1 [EC:2.3.1.48]
K11256 NCOA3, ACTR, KAT13B; nuclear receptor coactivator 3 [EC:2.3.1.48]
K04684 SP1; transcription factor Sp1
K04504 NR1C2, PPARD; peroxisome proliferator-activated receptor delta
K10056 JUP, PG; junction plakoglobin
K10055 ZBTB16, PLZF; zinc finger and BTB domain-containing protein 16
K08527 RARA, NR1B1; retinoic acid receptor alpha
K06627 CCNA; cyclin-A
K10054 PML, TRIM19; E3 SUMO-protein ligase PML [EC:2.3.2.-]
K08367 RUNX1, AML1; runt-related transcription factor 1
K10053 RUNX1T1, CBFA2T1; CBFA2/RNUX1 translocation partner 1
K09438 SPI1; transcription factor PU.1
K09055 CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
K05066 CSF2RA, GMCSFR, CD116; granulocyte-macrophage colony-stimulating factor receptor alpha
K05061 CSF3R, CD114; granulocyte colony-stimulating factor receptor
K05090 CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K06621 CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04453 MAX; Max protein
K10500 ZBTB17, MIZ1; zinc finger and BTB domain-containing protein 17
K04685 CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K03094 SKP1, CBF3D; S-phase kinase-associated protein 1
K03347 CUL1, CDC53; cullin 1
K03868 RBX1, ROC1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K03875 SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K11126 TERT, EST2; telomerase reverse transcriptase [EC:2.7.7.49]
K22183 TERC; telomerase RNA component
K09455 MITF; microphthalmia-associated transcription factor
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04462 MECOM, EVI1, PRDM3; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
K04496 CTBP; C-terminal binding protein [EC:1.1.1.428]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K08734 MLH1; DNA mismatch repair protein MLH1
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K08775 BRCA2, FANCD1; breast cancer 2 susceptibility protein
K04482 RAD51; DNA repair protein RAD51
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K10131 PMAIP1, NOXA; phorbol-12-myristate-13-acetate-induced protein 1
K10132 BBC3, PUMA; Bcl-2-binding component 3
K16341 BCL2L11, BIM; Bcl-2-like protein 11
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K10456 KLHL19, KEAP1, INRF2; kelch-like protein 19
K05638 NFE2L2, NRF2; nuclear factor erythroid 2-related factor 2
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K00799 GST, gst; glutathione S-transferase [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K03871 VHL; von Hippel-Lindau disease tumor supressor
K03872 ELOC, TCEB1; elongin-C
K03873 ELOB, TCEB2; elongin-B
K03870 CUL2; cullin 2
K09592 EGLN, HPH; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K01679 E4.2.1.2B, fumC, FH; fumarate hydratase, class II [EC:4.2.1.2]
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K09095 HIF2A, EPAS1; hypoxia-inducible factor 2 alpha
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K15589 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K07299 SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K06052 JAG1, CD339; jagged-1
K21635 JAG2; jagged-2
K06051 DLL; delta
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K06054 HES1; hairy and enhancer of split 1
K06055 HES5; hairy and enhancer of split 5
K09091 HEY; hairy and enhancer of split related with YRPW motif
K05097 FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K11988 SHH; sonic hedgehog
K06225 PTCH1; patched 1
K06226 SMO; smoothened
K18806 KIF7; kinesin family member 7
K06229 SUFU; suppressor of fused
K16797 GLI1; zinc finger protein GLI1
K16798 GLI2; zinc finger protein GLI2
K06230 GLI3; zinc finger protein GLI3
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K06231 HHIP; hedgehog interacting protein
K11101 PTCH2; patched 2
K08557 AR, NR3C4; androgen receptor
K04079 HSP90A, htpG; molecular chaperone HtpG
K09487 HSP90B, TRA1; heat shock protein 90kDa beta
K01351 KLK3, PSA; semenogelase [EC:3.4.21.77]
|
05202 Transcriptional misregulation in cancer [PATH:ko05202]
|
05206 MicroRNAs in cancer [PATH:ko05206]
|
K17002 MIR17; microRNA 17
K17003 MIR18A; microRNA 18a
K17005 MIR19A; microRNA 19a
K23559 MIR19B; microRNA 19b
K17006 MIR20A; microRNA 20a
K17008 MIR92A; microRNA 92a
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K17010 MIR221; microRNA 221
K17011 MIR222; microRNA 222
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K16863 MIR21; microRNA 21
K16866 TIMP3; metalloproteinase inhibitor 3
K16980 MIRLET7; microRNA let-7
K17397 MIRLET7C; microRNA let-7c
K07827 KRAS, KRAS2; GTPase KRas
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
K09283 HMGA2; high mobility group AT-hook protein 2
K17396 MIR107; microRNA 107
K16986 MIR15A; microRNA 15a
K16987 MIR15B; microRNA 15b
K16988 MIR16; microRNA 16
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K06626 CCNE; G1/S-specific cyclin-E1
K16978 MIR126; microRNA 126
K04438 CRK, CRKII; C-crk adapter molecule crk
K16972 MIR1; microRNA 1
K11406 HDAC4_5; histone deacetylase 4/5 [EC:3.5.1.98]
K23582 FOXP1; forkhead box protein P1
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K16995 MIR29A; microRNA 29a
K16996 MIR29B; microRNA 29b
K16997 MIR29C; microRNA 29c
K17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]
K17399 DNMT3B; DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]
K16970 MIR133A; microRNA 133a
K16971 MIR133B; microRNA 133b
K02539 MCL1; myeloid leukemia cell differntiation protein MCL-1
K02163 BCLW; apoptosis regulator BCL-W
K16974 MIR145; microRNA 145
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05448 VEGFA; vascular endothelial growth factor A
K17017 MIR200C; microRNA 200c
K09299 ZEB1; zinc finger homeobox protein 1
K17018 MIR141; microRNA 141
K13376 TGFB2; transforming growth factor beta-2
K17116 MIR183; microRNA 183
K08007 EZR, VIL2; ezrin
K16993 MIR125A; microRNA 125a
K16994 MIR125B; microRNA 125b
K16865 PDCD4; programmed cell death protein 4
K17023 MIR143; microRNA 143
K17131 MIR192; microRNA 192
K17371 MIR194; microRNA 194
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K17167 MIR215; microRNA 215
K17366 MIR28; microRNA 28
K17110 MIR30A_D_E; microRNA 30a/d/e
K17111 MIR30B; microRNA 30b
K17040 MIR30C; microRNA 30c
K10373 TPM1; tropomyosin 1
K17383 SPRY2; protein sprouty homolog 2
K02161 BCL2; apoptosis regulator Bcl-2
K10139 SERPINB5; serpin B5
K17009 MIR155; microRNA 155
K16975 MIR203; microRNA 203
K17150 MIR205; microRNA 205
K17112 MIR27A; microRNA 27a
K17113 MIR27B; microRNA 27b
K08670 ST14, PRSS14; suppressor of tumorigenicity protein 14 [EC:3.4.21.109]
K07410 CYP1B1; cytochrome P450 family 1 subfamily B1 [EC:1.14.14.1]
K17183 MIR31; microRNA 31
K17367 MIR99A; microRNA 99a
K17041 MIR100; microRNA 100
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07204 RAPTOR; regulatory associated protein of mTOR
K07436 CYP24A1; vitamin D3 24-hydroxylase [EC:1.14.15.16]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05084 ERBB3, HER3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K10149 TP63; tumor protein p63
K23560 ZEB2; zinc finger homeobox protein 2
K23551 FSCN1; fascin 1
K16976 MIR375; microRNA 375
K17379 MIR602; microRNA 602
K09850 RASSF1; Ras association domain-containing protein 1
K17393 MIR10B; microRNA 10b
K09295 HOXD10; homrobox protein Hox-D10
K08270 DDIT4, REDD1; DNA-damage-inducible transcript 4
K17460 BMF; Bcl-2-modifying factor
K17042 MIR224; microRNA 224
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K17036 MIR363; microRNA 363
K17378 MIR494; microRNA 494
K17380 MIR615; microRNA 615
K17381 MIR625; microRNA 625
K17038 MIR25; microRNA 25
K16982 MIR34A; microRNA 34a
K17114 MIR96; microRNA 96
K16864 MIR10A; microRNA 10a
K17165 MIR23A; microRNA 23a
K17394 MIR23B; microRNA 23b
K17395 MIR23C; microRNA 23c
K17020 MIR122; microRNA 122
K13863 SLC7A1, ATRC1; solute carrier family 7 (cationic amino acid transporter), member 1
K10145 CCNG1; cyclin G1
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K17024 MIR150; microRNA 150
K17001 MIR223; microRNA 223
K04381 STMN1; stathmin 1
K17132 MIR342; microRNA 342
K17376 MIR423; microRNA 423
K04692 STAT3; signal transducer and activator of transcription 3
K04377 MYC; Myc proto-oncogene protein
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K02833 HRAS; GTPase HRas
K07828 NRAS; GTPase NRas
K17119 MIR199B; microRNA 199b
K17152 MIR324; microRNA 324
K17137 MIR483; microRNA 483
K16984 MIR26A; microRNA 26a
K16985 MIR26B; microRNA 26b
K17370 MIR152; microRNA 152
K00558 DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
K17144 MIR135; microRNA 135
K02085 APC; adenomatosis polyposis coli protein
K16172 IRS1; insulin receptor substrate 1
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K17015 MIR200A; microRNA 200a
K17016 MIR200B; microRNA 200b
K12886 HNRNPK; heterogeneous nuclear ribonucleoprotein K
K17461 RECK, ST15; reversion-inducing-cysteine-rich protein with kazal motifs
K17126 MIR124; microRNA 124
K17369 MIR137; microRNA 137
K17130 MIR128; microRNA 128
K06620 E2F3; transcription factor E2F3
K17365 MIR7; microRNA 7
K07187 IRS2; insulin receptor substrate 2
K17372 MIR326; microRNA 326
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K11459 PCGF4, BMI1; polycomb group RING finger protein 4
K17012 MIR146A; microRNA 146a
K07996 MMP16; matrix metalloproteinase-16 (membrane-inserted) [EC:3.4.24.-]
K17025 MIR181A; microRNA 181a
K17026 MIR181B; microRNA 181b
K17027 MIR181C; microRNA 181c
K17028 MIR181D; microRNA 181d
K04728 ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]
K04694 SOCS1, JAB; suppressor of cytokine signaling 1
K17000 MIR373; microRNA 373
K17175 MIR520; microRNA 520
K06256 CD44; CD44 antigen
K16989 MIR103; microRNA 103
K11592 DICER1, DCR1; endoribonuclease Dicer [EC:3.1.26.-]
K02329 FZD3; frizzled 3
K06484 ITGA5, CD49e; integrin alpha 5
K05762 RDX; radixin
K04513 RHOA; Ras homolog gene family, member A
K17148 MIR193B; microRNA 193b
K01348 PLAU; urokinase plasminogen activator [EC:3.4.21.73]
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K17442 ZFPM2, FOG2; zinc finger protein ZFPM2
K06493 ITGB3, CD61; integrin beta 3
K10577 UBE2I, UBC9; ubiquitin-conjugating enzyme E2 I
K17033 MIR335; microRNA 335
K23581 SOX4; transcription factor SOX4 (SOX group C)
K06252 TN; tenascin
K16973 MIR206; microRNA 206
K17172 MIR451; microRNA 451
K05658 ABCB1, CD243; ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:7.6.2.2]
K17375 MIR345; microRNA 345
K05665 ABCC1; ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3]
K17151 MIR214; microRNA 214
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K17035 MIR106B; microRNA 106b
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K17178 MIR210; microRNA 210
K05462 EFNA; ephrin-A
K16857 THBS1; thrombospondin 1
K17391 IGF2BP1; insulin-like growth factor 2 mRNA-binding protein 1
K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
K16983 MIR34B; microRNA 34b
K23572 MIR34C; microRNA 34c
K16977 MIR9; microRNA 9
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K17118 MIR199A; microRNA 199a
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04364 GRB2; growth factor receptor-bound protein 2
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K04445 RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K04451 TP53, P53; tumor protein p53
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K10127 MDM4, MDMX; protein Mdm4
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K17129 MIR101; microRNA 101
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K17029 MIR195; microRNA 195
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K03099 SOS; son of sevenless
K06279 SHC1; SHC-transforming protein 1
K04359 PDGFA; platelet-derived growth factor subunit A
K17368 MIR129; microRNA 129
K17449 SHC4; SHC-transforming protein 4
K17386 PDGFB; platelet-derived growth factor subunit B
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K06621 CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K17039 MIR32; microRNA 32
K16341 BCL2L11, BIM; Bcl-2-like protein 11
K12561 MARCKS; myristoylated alanine-rich C-kinase substrate
K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
K17377 MIR449A; microRNA 449a
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K11430 EZH2; [histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:2.1.1.356]
K01425 glsA, GLS; glutaminase [EC:3.5.1.2]
K11411 SIRT1, SIR2L1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K00312 WNT3; wingless-type MMTV integration site family, member 3
K17373 MIR330; microRNA 330
K17374 MIR331; microRNA 331
K17390 CDCA5; sororin
K17387 KIF23; kinesin family member 23
K17389 MIR520C; microRNA 520c
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K15379 SLC45A3; solute carrier family 45, member 3
K07606 VIM; vimentin
|
05205 Proteoglycans in cancer [PATH:ko05205]
|
05204 Chemical carcinogenesis - DNA adducts [PATH:ko05204]
|
05207 Chemical carcinogenesis - receptor activation [PATH:ko05207]
|
05208 Chemical carcinogenesis - reactive oxygen species [PATH:ko05208]
|
K07755 AS3MT; arsenite methyltransferase [EC:2.1.1.137]
K00799 GST, gst; glutathione S-transferase [EC:2.5.1.18]
K03878 ND1; NADH-ubiquinone oxidoreductase chain 1 [EC:7.1.1.2]
K03879 ND2; NADH-ubiquinone oxidoreductase chain 2 [EC:7.1.1.2]
K03880 ND3; NADH-ubiquinone oxidoreductase chain 3 [EC:7.1.1.2]
K03881 ND4; NADH-ubiquinone oxidoreductase chain 4 [EC:7.1.1.2]
K03882 ND4L; NADH-ubiquinone oxidoreductase chain 4L [EC:7.1.1.2]
K03883 ND5; NADH-ubiquinone oxidoreductase chain 5 [EC:7.1.1.2]
K03884 ND6; NADH-ubiquinone oxidoreductase chain 6 [EC:7.1.1.2]
K03942 NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
K03943 NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:7.1.1.2]
K03944 NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
K03945 NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1
K03946 NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2
K03947 NDUFA3; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3
K03948 NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K03949 NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5
K03950 NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6
K03951 NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7
K03952 NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8
K03953 NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9
K03954 NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10
K03955 NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1, acyl-carrier protein
K03956 NDUFA11; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11
K11352 NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12
K11353 NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13
K03957 NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
K03959 NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3
K03960 NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4
K03961 NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5
K03962 NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6
K03963 NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7
K03964 NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8
K03965 NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9
K03966 NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10
K11351 NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
K03934 NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:7.1.1.2]
K03935 NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:7.1.1.2]
K03936 NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:7.1.1.2]
K03937 NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
K03938 NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5
K03939 NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6
K03940 NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:7.1.1.2]
K03941 NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:7.1.1.2]
K03967 NDUFC1; NADH dehydrogenase (ubiquinone) 1 subunit C1
K03968 NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
K00234 SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
K00235 SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
K00236 SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
K00237 SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
K00411 UQCRFS1, RIP1, petA; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
K00412 CYTB, petB; ubiquinol-cytochrome c reductase cytochrome b subunit
K00413 CYC1, CYT1, petC; ubiquinol-cytochrome c reductase cytochrome c1 subunit
K00414 QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
K00415 QCR2, UQCRC2; ubiquinol-cytochrome c reductase core subunit 2
K00416 QCR6, UQCRH; ubiquinol-cytochrome c reductase subunit 6
K00417 QCR7, UQCRB; ubiquinol-cytochrome c reductase subunit 7
K00418 QCR8, UQCRQ; ubiquinol-cytochrome c reductase subunit 8
K00419 QCR9, UCRC; ubiquinol-cytochrome c reductase subunit 9
K00420 QCR10, UQCR; ubiquinol-cytochrome c reductase subunit 10
K02262 COX3; cytochrome c oxidase subunit 3
K02256 COX1; cytochrome c oxidase subunit 1 [EC:7.1.1.9]
K02261 COX2; cytochrome c oxidase subunit 2
K02263 COX4; cytochrome c oxidase subunit 4
K02264 COX5A; cytochrome c oxidase subunit 5a
K02265 COX5B; cytochrome c oxidase subunit 5b
K02266 COX6A; cytochrome c oxidase subunit 6a
K02267 COX6B; cytochrome c oxidase subunit 6b
K02268 COX6C; cytochrome c oxidase subunit 6c
K02270 COX7A; cytochrome c oxidase subunit 7a
K02271 COX7B; cytochrome c oxidase subunit 7b
K02272 COX7C; cytochrome c oxidase subunit 7c
K02273 COX8; cytochrome c oxidase subunit 8
K02132 ATPeF1A, ATP5A1, ATP1; F-type H+-transporting ATPase subunit alpha
K02133 ATPeF1B, ATP5B, ATP2; F-type H+-transporting ATPase subunit beta [EC:7.1.2.2]
K02136 ATPeF1G, ATP5C1, ATP3; F-type H+-transporting ATPase subunit gamma
K02134 ATPeF1D, ATP5D, ATP16; F-type H+-transporting ATPase subunit delta
K02135 ATPeF1E, ATP5E, ATP15; F-type H+-transporting ATPase subunit epsilon
K02126 ATPeF0A, MTATP6, ATP6; F-type H+-transporting ATPase subunit a
K02127 ATPeF0B, ATP5F1, ATP4; F-type H+-transporting ATPase subunit b
K02128 ATPeF0C, ATP5G, ATP9; F-type H+-transporting ATPase subunit c
K02138 ATPeF0D, ATP5H, ATP7; F-type H+-transporting ATPase subunit d
K02137 ATPeF0O, ATP5O, ATP5; F-type H+-transporting ATPase subunit O
K02131 ATPeF0F6, ATP5J; F-type H+-transporting ATPase subunit 6
K02125 ATPeF08, MTATP8, ATP8; F-type H+-transporting ATPase subunit 8
K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K05863 SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
K04565 SOD1; superoxide dismutase, Cu-Zn family [EC:1.15.1.1]
K03781 katE, CAT, catB, srpA; catalase [EC:1.11.1.6]
K14700 SLC26A1, SAT1; solute carrier family 26 (sulfate anion transporter), member 1
K14701 SLC26A2, DTD; solute carrier family 26 (sulfate anion transporter), member 2
K14704 SLC26A6; solute carrier family 26 (sulfate anion transporter), member 6
K14706 SLC26A9; solute carrier family 26 (sulfate anion transporter), member 9
K07409 CYP1A2; cytochrome P450 family 1 subfamily A2 [EC:1.14.14.1]
K07415 CYP2E1; cytochrome P450 family 2 subfamily E1 [EC:1.14.14.-]
K07416 CYP2F; cytochrome P450 family 2 subfamily F [EC:1.14.14.1]
K07408 CYP1A1; cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1]
K07410 CYP1B1; cytochrome P450 family 1 subfamily B1 [EC:1.14.14.1]
K01253 EPHX1; microsomal epoxide hydrolase [EC:3.3.2.9]
K08726 EPHX2; soluble epoxide hydrolase / lipid-phosphate phosphatase [EC:3.3.2.10 3.1.3.76]
K22368 EPHX3; epoxide hydrolase 3 [EC:3.3.2.10]
K22369 EPHX4; epoxide hydrolase 4 [EC:3.3.-.-]
K00002 AKR1A1, adh; alcohol dehydrogenase (NADP+) [EC:1.1.1.2]
K00212 AKR1C1; 20alpha/3alpha-hydroxysteroid dehydrogenase / dihydrodiol dehydrogenase [EC:1.1.1.149 1.1.1.357 1.3.1.20]
K00089 AKR1C2; 3alpha-hydroxysteroid 3-dehydrogenase [EC:1.1.1.213 1.1.1.357]
K04119 AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
K00037 AKR1C4; 3alpha-hydroxysteroid 3-dehydrogenase / chlordecone reductase [EC:1.1.1.50 1.1.1.357 1.1.1.225]
K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K00079 CBR1; carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
K09093 AHR; aryl hydrocarbon receptor
K12550 LPO; lactoperoxidase [EC:1.11.1.7]
K21423 NOX4, RENOX; NADPH oxidase 4 [EC:1.6.3.-]
K08009 CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
K08008 NOX1, MOX1; NADPH oxidase 1
K08011 NCF1, P47PHOX; neutrophil cytosolic factor 1
K08010 NCF2, P67PHOX; neutrophil cytosolic factor 2
K04357 EGF; epidermal growth factor
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05460 HGF; hepatocyte growth factor
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K09408 FOXO3; forkhead box protein O3
K02158 BAD; Bcl-2-antagonist of cell death
K05696 PTPN1, PTP1B; tyrosine-protein phosphatase non-receptor type 1 [EC:3.1.3.48]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K05698 PTPRJ, DEP1, CD148; receptor-type tyrosine-protein phosphatase eta [EC:3.1.3.48]
K14394 ACP1; low molecular weight phosphotyrosine protein phosphatase [EC:3.1.3.2 3.1.3.48]
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K08887 ABL2; abelson tyrosine-protein kinase 2 [EC:2.7.10.2]
K06070 PKD; protein kinase D [EC:2.7.11.13]
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K05448 VEGFA; vascular endothelial growth factor A
K10456 KLHL19, KEAP1, INRF2; kelch-like protein 19
K05638 NFE2L2, NRF2; nuclear factor erythroid 2-related factor 2
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
|
05203 Viral carcinogenesis [PATH:ko05203]
|
05230 Central carbon metabolism in cancer [PATH:ko05230]
|
K07299 SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K07593 SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
K12407 GCK; glucokinase [EC:2.7.1.2]
K00873 PK, pyk; pyruvate kinase [EC:2.7.1.40]
K00161 PDHA, pdhA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
K00162 PDHB, pdhB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
K12077 PDK1; pyruvate dehydrogenase kinase isoform 1 [EC:2.7.11.2]
K04451 TP53, P53; tumor protein p53
K23755 SCO2; protein SCO2
K05616 SLC1A5; solute carrier family 1 (neutral amino acid transporter), member 5
K11413 SIRT3, SIR2L3; NAD-dependent protein deacetylase sirtuin 3 [EC:2.3.1.286]
K08180 SLC16A3; MFS transporter, MCT family, solute carrier family 16 (monocarboxylic acid transporters), member 3
K11416 SIRT6, SIR2L6; NAD-dependent protein deacetylase sirtuin 6 [EC:2.3.1.286]
K04377 MYC; Myc proto-oncogene protein
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K05091 KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K05101 NTRK3, TRKC; neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1]
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05092 FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K01425 glsA, GLS; glutaminase [EC:3.5.1.2]
K00036 G6PD, zwf; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
K00844 HK; hexokinase [EC:2.7.1.1]
K00850 pfkA, PFK; 6-phosphofructokinase 1 [EC:2.7.1.11]
K01834 PGAM, gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
K00016 LDH, ldh; L-lactate dehydrogenase [EC:1.1.1.27]
K00031 IDH1, IDH2, icd; isocitrate dehydrogenase [EC:1.1.1.42]
K14634 TIGAR; fructose-2,6-bisphosphatase [EC:3.1.3.46]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K13780 SLC7A5, LAT1; solute carrier family 7 (L-type amino acid transporter), member 5
|
05231 Choline metabolism in cancer [PATH:ko05231]
|
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer [PATH:ko05235]
|
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K04357 EGF; epidermal growth factor
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K15420 EML4; echinoderm microtubule-associated protein-like 4
K05119 ALK, CD246; anaplastic lymphoma kinase [EC:2.7.10.1]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02581 NFKBIB; NF-kappa-B inhibitor beta
K05872 NFKBIE; NF-kappa-B inhibitor epsilon
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04687 IFNG; interferon gamma
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K04692 STAT3; signal transducer and activator of transcription 3
K10159 TLR2, CD282; toll-like receptor 2
K10160 TLR4, CD284; toll-like receptor 4
K10161 TLR9, CD289; toll-like receptor 9
K05403 TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
K04729 MYD88; myeloid differentiation primary response protein MyD88
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K05842 TRIF; toll-like receptor adapter molecule 1
K05409 TIRP, TRAM; TRIF-related adaptor molecule
K06745 PDL1, CD274; programmed cell death 1 ligand 1
K06744 PDCD1, PD1, CD279; programmed cell death protein 1
K05697 PTPN6, SHP1; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K09034 BATF; ATF-like basic leucine zipper transcriptional factor
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03115 CSNK2B; casein kinase II subunit beta
K06454 CD4; T-cell surface glycoprotein CD4
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K06453 CD3Z, CD247; CD3Z antigen, zeta polypeptide
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K04421 MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K07362 LAT; linker for activation of T cells family member 1
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04350 RASGRP1; RAS guanyl-releasing protein 1
K06470 CD28; CD28 antigen
K18052 PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
|
|
09162 Cancer: specific types
|
05210 Colorectal cancer [PATH:ko05210]
|
05212 Pancreatic cancer [PATH:ko05212]
|
05225 Hepatocellular carcinoma [PATH:ko05225]
|
K08774 TGFA; transforming growth factor, alpha
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K13769 IGF2; insulin-like growth factor 2
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04375 ELK1; ETS domain-containing protein Elk-1
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K04377 MYC; Myc proto-oncogene protein
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K11126 TERT, EST2; telomerase reverse transcriptase [EC:2.7.7.49]
K22183 TERC; telomerase RNA component
K04451 TP53, P53; tumor protein p53
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K06621 CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7, fz; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4, fz4, CD344; frizzled 4
K02375 FZD5_8, fz2; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10, CD349_50; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02105 CTNNB1; catenin beta 1
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K02620 TCF7, TCF-1; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K10456 KLHL19, KEAP1, INRF2; kelch-like protein 19
K05638 NFE2L2, NRF2; nuclear factor erythroid 2-related factor 2
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K00799 GST, gst; glutathione S-transferase [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K05460 HGF; hepatocyte growth factor
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K09593 GAB1; GRB2-associated-binding protein 1
K05692 ACTB_G1; actin beta/gamma 1
K11340 ACTL6A, INO80K; actin-like protein 6A
K11652 ACTL6B; actin-like protein 6B
K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
K22197 BAF45A, PHF10; BRG1-associated factor 45A
K22198 BAF45B_C, DPF1_3; BRG1-associated factor 45B/C
K11653 ARID1; AT-rich interactive domain-containing protein 1
K11651 SMARCE1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1
K11648 SMARCB1, SNF5, INI1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
K11649 SMARCC; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C
K11647 SMARCA2_4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:5.6.2.-]
K11765 ARID2; AT-rich interactive domain-containing protein 2
K11757 PBRM1, PB1; protein polybromo-1
K11723 BRD7; bromodomain-containing protein 7
|
05226 Gastric cancer [PATH:ko05226]
|
05214 Glioma [PATH:ko05214]
|
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02183 CALM; calmodulin
K08794 CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K05869 CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K06621 CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53, P53; tumor protein p53
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K04503 CCND1; G1/S-specific cyclin-D1
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
|
05216 Thyroid cancer [PATH:ko05216]
|
05221 Acute myeloid leukemia [PATH:ko05221]
|
05220 Chronic myeloid leukemia [PATH:ko05220]
|
05217 Basal cell carcinoma [PATH:ko05217]
|
05218 Melanoma [PATH:ko05218]
|
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K05460 HGF; hepatocyte growth factor
K05459 IGF1; insulin-like growth factor 1
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K04357 EGF; epidermal growth factor
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04503 CCND1; G1/S-specific cyclin-D1
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K06621 CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53, P53; tumor protein p53
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K05689 CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K09455 MITF; microphthalmia-associated transcription factor
|
05211 Renal cell carcinoma [PATH:ko05211]
|
05219 Bladder cancer [PATH:ko05219]
|
05215 Prostate cancer [PATH:ko05215]
|
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K09633 TMPRSS2; transmembrane protease serine 2 [EC:3.4.21.122]
K09435 ERG; transcriptional regulator ERG
K01348 PLAU; urokinase plasminogen activator [EC:3.4.21.73]
K01343 PLAT; tissue plasminogen activator [EC:3.4.21.68]
K01394 MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K09299 ZEB1; zinc finger homeobox protein 1
K04387 IL1R2, CD121b; interleukin 1 receptor type II
K15619 SPINT1; Kunitz-type protease inhibitor 1
K15593 ETV5; ets translocation variant 5
K04526 INS; insulin
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K05459 IGF1; insulin-like growth factor 1
K05086 INSRR; insulin receptor-related receptor [EC:2.7.10.1]
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K09348 NKX3-1; homeobox protein Nkx-3.1
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02158 BAD; Bcl-2-antagonist of cell death
K07201 FOXO1; forkhead box protein O1
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53, P53; tumor protein p53
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K02105 CTNNB1; catenin beta 1
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K02620 TCF7, TCF-1; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04503 CCND1; G1/S-specific cyclin-D1
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K02161 BCL2; apoptosis regulator Bcl-2
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K12344 SRD5A2; 3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:1.3.1.22]
K08557 AR, NR3C4; androgen receptor
K04079 HSP90A, htpG; molecular chaperone HtpG
K09487 HSP90B, TRA1; heat shock protein 90kDa beta
K01351 KLK3, PSA; semenogelase [EC:3.4.21.77]
|
05213 Endometrial cancer [PATH:ko05213]
|
K04357 EGF; epidermal growth factor
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K06272 ILK; integrin-linked kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02158 BAD; Bcl-2-antagonist of cell death
K09408 FOXO3; forkhead box protein O3
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04375 ELK1; ETS domain-containing protein Elk-1
K08734 MLH1; DNA mismatch repair protein MLH1
K05689 CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
K02105 CTNNB1; catenin beta 1
K05691 CTNNA; catenin alpha
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02620 TCF7, TCF-1; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K04451 TP53, P53; tumor protein p53
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
|
05224 Breast cancer [PATH:ko05224]
|
K08550 ESR1, NR3A1; estrogen receptor alpha
K08551 ESR2, NR3A2; estrogen receptor beta
K09101 NCOA1, SRC1, KAT13A; nuclear receptor coactivator 1 [EC:2.3.1.48]
K11256 NCOA3, ACTR, KAT13B; nuclear receptor coactivator 3 [EC:2.3.1.48]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K04684 SP1; transcription factor Sp1
K04503 CCND1; G1/S-specific cyclin-D1
K04377 MYC; Myc proto-oncogene protein
K08556 PGR, NR3C3; progesterone receptor
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00408 WNT4; wingless-type MMTV integration site family, member 4
K05473 TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04357 EGF; epidermal growth factor
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05091 KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K06052 JAG1, CD339; jagged-1
K21635 JAG2; jagged-2
K06051 DLL; delta
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K06054 HES1; hairy and enhancer of split 1
K06055 HES5; hairy and enhancer of split 5
K09091 HEY; hairy and enhancer of split related with YRPW motif
K05097 FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7, fz; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4, fz4, CD344; frizzled 4
K02375 FZD5_8, fz2; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10, CD349_50; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02105 CTNNB1; catenin beta 1
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K02620 TCF7, TCF-1; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04451 TP53, P53; tumor protein p53
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K08775 BRCA2, FANCD1; breast cancer 2 susceptibility protein
|
05222 Small cell lung cancer [PATH:ko05222]
|
K01522 FHIT; bis(5'-adenosyl)-triphosphatase [EC:3.6.1.29]
K08528 RARB, NR1B2; retinoic acid receptor beta
K08524 RXRA, NR2B1; retinoid X receptor alpha
K08525 RXRB, NR2B2; retinoid X receptor beta
K08526 RXRG, NR2B3; retinoid X receptor gamma
K04451 TP53, P53; tumor protein p53
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K02161 BCL2; apoptosis regulator Bcl-2
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04377 MYC; Myc proto-oncogene protein
K04453 MAX; Max protein
K10500 ZBTB17, MIZ1; zinc finger and BTB domain-containing protein 17
K04685 CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K03875 SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K06237 COL4A; collagen type IV alpha
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K05717 FN1; fibronectin 1
K06481 ITGA2, CD49b; integrin alpha 2
K06476 ITGA2B, CD41; integrin alpha 2B
K06482 ITGA3, CD49c; integrin alpha 3
K06485 ITGA6, CD49f; integrin alpha 6
K06487 ITGAV, CD51; integrin alpha V
K05719 ITGB1, CD29; integrin beta 1
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K03172 TRAF1; TNF receptor-associated factor 1
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K03174 TRAF3; TNF receptor-associated factor 3
K09848 TRAF4; TNF receptor-associated factor 4
K09849 TRAF5; TNF receptor-associated factor 5
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
|
05223 Non-small cell lung cancer [PATH:ko05223]
|
|
09172 Infectious disease: viral
|
05166 Human T-cell leukemia virus 1 infection [PATH:ko05166]
|
K24862 gp46; HTLV envelope surface glycoprotein gp46
K24863 gp21; HTLV envelope transmembrane protein gp21
K07299 SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K06724 NRP1, CD304; neuropilin 1
K04377 MYC; Myc proto-oncogene protein
K08874 TRRAP; transformation/transcription domain-associated protein
K11304 TIP60, KAT5, ESA1; histone acetyltransferase HTATIP [EC:2.3.1.48]
K10151 CCND2; G1/S-specific cyclin-D2
K23068 p30II; HTLV-1 accessory protein p30II
K05718 ITGAL, CD11a; integrin alpha L
K06464 ITGB2, CD18; integrin beta 2
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K06454 CD4; T-cell surface glycoprotein CD4
K19259 env; Deltaretrovirus envelope glycoprotein gp62
K25051 MA; HTLV-1 matrix protein
K06271 TLN; talin
K23069 p12I; HTLV-1 accessory protein p12I
K23018 rex; HTLV-1 rex polyprotein
K15304 RANBP3; Ran-binding protein 3
K07936 RAN; GTP-binding nuclear protein Ran
K14290 XPO1, CRM1; exportin-1
K08057 CALR; calreticulin
K08054 CANX; calnexin
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
K05069 IL2RB, CD122; interleukin 2 receptor beta
K05070 IL2RG, CD132; interleukin 2 receptor gamma
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K05429 IL2; interleukin 2
K06751 MHC1; MHC class I antigen
K08055 B2M; beta-2-microglobulin
K00787 FDPS; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]
K23070 p13; HTLV-1 accessory protein p13
K05862 VDAC1; voltage-dependent anion channel protein 1
K05863 SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K05770 TSPO, BZRP; translocator protein
K15305 VAC14, TAX1BP2; vacuole morphology and inheritance protein 14
K15306 RANBP1; Ran-binding protein 1
K21857 tax; Deltaretrovirus protein Tax-1
K06679 MAD1; mitotic spindle assembly checkpoint protein MAD1
K02537 MAD2; mitotic spindle assembly checkpoint protein MAD2
K06637 BUB1B, BUBR1, MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta [EC:2.7.11.1]
K02180 BUB3; cell cycle arrest protein BUB3
K03348 APC1, ANAPC1; anaphase-promoting complex subunit 1
K03349 APC2, ANAPC2; anaphase-promoting complex subunit 2
K03350 APC3, CDC27; anaphase-promoting complex subunit 3
K03351 APC4, ANAPC4; anaphase-promoting complex subunit 4
K03352 APC5, ANAPC5; anaphase-promoting complex subunit 5
K03353 APC6, CDC16; anaphase-promoting complex subunit 6
K03354 APC7, ANAPC7; anaphase-promoting complex subunit 7
K03355 APC8, CDC23; anaphase-promoting complex subunit 8
K03357 APC10, ANAPC10, DOC1; anaphase-promoting complex subunit 10
K03358 APC11, ANAPC11; anaphase-promoting complex subunit 11
K03359 APC12, CDC26; anaphase-promoting complex subunit 12
K12456 APC13, ANAPC13; anaphase-promoting complex subunit 13
K25228 APC15, ANAPC15; anaphase-promoting complex subunit 15
K25229 APC16, ANAPC16; anaphase-promoting complex subunit 16
K03363 CDC20; cell division cycle 20, cofactor of APC complex
K06635 PTTG; securin
K02365 ESP1; separase [EC:3.4.22.49]
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K04685 CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
K06621 CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K10152 CCND3; G1/S-specific cyclin-D3
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K06627 CCNA; cyclin-A
K06626 CCNE; G1/S-specific cyclin-E1
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04728 ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K04451 TP53, P53; tumor protein p53
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K12076 DLG1; disks large protein 1
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K04416 MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K01397 MMP7; matrix metalloproteinase-7 (matrilysin, uterine) [EC:3.4.24.23]
K23071 HBZ; HTLV-1 basic zipper factor
K04386 IL1R1, CD121a; interleukin 1 receptor type I
K04387 IL1R2, CD121b; interleukin 1 receptor type II
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K04421 MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K15307 GPS2; G protein pathway suppressor 2
K03159 TNFRSF3, LTBR; lymphotoxin beta receptor TNFR superfamily member 3
K03160 TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
K05151 TNFRSF13C, BAFFR, CD268; tumor necrosis factor receptor superfamily member 13C
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K09253 RELB; transcription factor RelB
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K15308 TTP; tristetraprolin
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05433 IL15; interleukin 15
K05074 IL15RA, CD215; interleukin 15 receptor alpha
K05405 IL6; interleukin 6
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K05468 LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K08065 NFYB, HAP3; nuclear transcription Y subunit beta
K06752 MHC2; MHC class II antigen
K04378 SRF; serum response factor
K04376 ELK4, SAP1; ETS domain-containing protein Elk-4
K04375 ELK1; ETS domain-containing protein Elk-1
K09438 SPI1; transcription factor PU.1
K02678 ETS1, pnt; C-ets-1
K21932 ETS2; C-ets-2
K03120 TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
K04379 FOS; proto-oncogene protein c-fos
K09203 EGR1; early growth response protein 1
K04502 FOSL1; fos-like antigen 1
K12496 EGR2; early growth response protein 2
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K15309 CRTC1, TORC1; CREB-regulated transcription coactivator 1
K16333 CRTC2, TORC2; CREB-regulated transcription coactivator 2
K16334 CRTC3, TORC3; CREB-regulated transcription coactivator 3
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K06062 PCAF, KAT2, GCN5; histone acetyltransferase [EC:2.3.1.48]
K09063 TCF3, E2A; transcription factor E2-alpha
K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K02159 BAX; apoptosis regulator BAX
K06622 CDKN2C, P18, INK4C; cyclin-dependent kinase inhibitor 2C
K11126 TERT, EST2; telomerase reverse transcriptase [EC:2.7.7.49]
K09341 MSX; homeobox protein MSX
K25052 CA; HTLV-1 capsid protein
K25053 NC; HTLV-1 nucleocapsid protein
K25054 PR; HTLV-1 protease [EC:3.4.23.-]
K25055 RT; HTLV-1 reverse transcriptase / ribonuclease H [EC:2.7.7.49 2.7.7.7 3.1.26.4]
K25056 IN; HTLV-1 integrase
|
05170 Human immunodeficiency virus 1 infection [PATH:ko05170]
|
05161 Hepatitis B [PATH:ko05161]
|
05160 Hepatitis C [PATH:ko05160]
|
05171 Coronavirus disease - COVID-19 [PATH:ko05171]
|
05164 Influenza A [PATH:ko05164]
|
05162 Measles [PATH:ko05162]
|
05168 Herpes simplex virus 1 infection [PATH:ko05168]
|
05163 Human cytomegalovirus infection [PATH:ko05163]
|
05167 Kaposi sarcoma-associated herpesvirus infection [PATH:ko05167]
|
05169 Epstein-Barr virus infection [PATH:ko05169]
|
05165 Human papillomavirus infection [PATH:ko05165]
|
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7, fz; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4, fz4, CD344; frizzled 4
K02375 FZD5_8, fz2; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10, CD349_50; frizzled 9/10
K02353 DVL; segment polarity protein dishevelled
K21807 E6; Alphapapillomavirus protein E6
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02105 CTNNB1; catenin beta 1
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K11126 TERT, EST2; telomerase reverse transcriptase [EC:2.7.7.49]
K02620 TCF7, TCF-1; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K10587 UBE3A, E6AP; ubiquitin-protein ligase E3 A [EC:2.3.2.26]
K05401 TLR3, CD283; toll-like receptor 3
K05842 TRIF; toll-like receptor adapter molecule 1
K03174 TRAF3; TNF receptor-associated factor 3
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K05411 IRF3; interferon regulatory factor 3
K05415 IFNB; interferon beta
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K11315 TADA3, ADA3, NGG1; transcriptional adapter 3
K04451 TP53, P53; tumor protein p53
K19260 L1; Papillomaviridae major capsid protein L1
K21808 L2; Alphapapillomavirus minor capsid protein L2
K05631 AIP3, WWP3, BAIAP1; atrophin-1 interacting protein 3 (BAI1-associated protein 1)
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04237 PARD3; partitioning defective protein 3
K06093 PARD6; partitioning defective protein 6
K06069 PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K04393 CDC42; cell division control protein 42
K16175 SCRIB; protein scribble
K12076 DLG1; disks large protein 1
K12075 DLG2; discs large protein 2
K21098 DLG3; discs large protein 3
K06094 LLGL; lethal(2) giant larvae protein
K06090 CRB3; crumbs 3
K06092 INADL, PATJ; InaD-like protein
K06091 MPP5, PALS1; MAGUK p55 subfamily member 5
K03900 VWF; von Willebrand factor
K16857 THBS1; thrombospondin 1
K04659 THBS2S; thrombospondin 2/3/4/5
K05717 FN1; fibronectin 1
K06236 COL1A; collagen type I alpha
K19719 COL2A; collagen type II alpha
K06237 COL4A; collagen type IV alpha
K06238 COL6A; collagen type VI alpha
K08131 COL9A; collagen type IX alpha
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K06248 CHAD; chondroadherin
K06249 RELN; reelin [EC:3.4.21.-]
K06250 SPP1, BNSP, OPN; secreted phosphoprotein 1
K06251 VTN; vitronectin
K06252 TN; tenascin
K06253 IBSP; integrin binding sialoprotein
K06480 ITGA1, CD49a; integrin alpha 1
K06481 ITGA2, CD49b; integrin alpha 2
K06476 ITGA2B, CD41; integrin alpha 2B
K06482 ITGA3, CD49c; integrin alpha 3
K06483 ITGA4, CD49d; integrin alpha 4
K06484 ITGA5, CD49e; integrin alpha 5
K06485 ITGA6, CD49f; integrin alpha 6
K06583 ITGA7; integrin alpha 7
K06584 ITGA8; integrin alpha 8
K06585 ITGA9; integrin alpha 9
K06586 ITGA10; integrin alpha 10
K06587 ITGA11; integrin alpha 11
K06487 ITGAV, CD51; integrin alpha V
K05719 ITGB1, CD29; integrin beta 1
K06493 ITGB3, CD61; integrin beta 3
K06525 ITGB4, CD104; integrin beta 4
K06588 ITGB5; integrin beta 5
K06589 ITGB6; integrin beta 6
K06590 ITGB7; integrin beta 7
K06591 ITGB8; integrin beta 8
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K05760 PXN; paxillin
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K13365 SLC9A3R1, NHERF1; sodium/hydrogen exchange regulatory cofactor NHE-RF1
K21809 E7; Alphapapillomavirus protein E7
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K21810 E1; Alphapapillomavirus replication protein E1 [EC:5.6.2.-]
K21811 E2; Alphapapillomavirus regulatory protein E2
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K02158 BAD; Bcl-2-antagonist of cell death
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07201 FOXO1; forkhead box protein O1
K21812 E5; Alphapapillomavirus protein E5
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K04681 RBL1; retinoblastoma-like protein 1
K16332 RBL2; retinoblastoma-like protein 2
K03062 PSMC1, RPT2; 26S proteasome regulatory subunit T2
K17454 E2F1; transcription factor E2F1
K06627 CCNA; cyclin-A
K04728 ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K05448 VEGFA; vascular endothelial growth factor A
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K12236 NFX1; transcriptional repressor NF-X1
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K11643 CHD4, MI2B; chromodomain-helicase-DNA-binding protein 4 [EC:5.6.2.-]
K09444 IRF1; interferon regulatory factor 1
K03120 TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
K06751 MHC1; MHC class I antigen
K14009 BCAP31, BAP31; B-cell receptor-associated protein 31
K02145 ATPeV1A, ATP6A; V-type H+-transporting ATPase subunit A [EC:7.1.2.2]
K02147 ATPeV1B, ATP6B; V-type H+-transporting ATPase subunit B
K02148 ATPeV1C, ATP6C; V-type H+-transporting ATPase subunit C
K02149 ATPeV1D, ATP6M; V-type H+-transporting ATPase subunit D
K02150 ATPeV1E, ATP6E; V-type H+-transporting ATPase subunit E
K02151 ATPeV1F, ATP6S14; V-type H+-transporting ATPase subunit F
K02152 ATPeV1G, ATP6G; V-type H+-transporting ATPase subunit G
K02144 ATPeV1H; V-type H+-transporting ATPase subunit H
K02154 ATPeV0A, ATP6N; V-type H+-transporting ATPase subunit a
K02146 ATPeV0D, ATP6D; V-type H+-transporting ATPase subunit d
K02153 ATPeV0E, ATP6H; V-type H+-transporting ATPase subunit e
K02155 ATPeV0C, ATP6L; V-type H+-transporting ATPase 16kDa proteolipid subunit
K03661 ATPeV0B, ATP6F; V-type H+-transporting ATPase 21kDa proteolipid subunit
K03662 ATPeVS1, ATP6S1; V-type H+-transporting ATPase S1 subunit
K04357 EGF; epidermal growth factor
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K04261 PTGER4; prostaglandin E receptor 4
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K04345 PKA; protein kinase A [EC:2.7.11.11]
K02159 BAX; apoptosis regulator BAX
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K10691 UBR4, ZUBR1; E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27]
K10389 TUBG; tubulin gamma
K00873 PK, pyk; pyruvate kinase [EC:2.7.1.40]
K05414 IFNA; interferon alpha
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04693 IRF9, ISGF3G, P48; interferon regulatory factor 9
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
K14608 OASL; 2'-5'-oligoadenylate synthase-like protein
K14754 MX; interferon-induced GTP-binding protein Mx
K12159 ISG15; ubiquitin cross-reactive protein
K06052 JAG1, CD339; jagged-1
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K04505 PSEN1, PS1; presenilin 1 [EC:3.4.23.-]
K05948 FNG; fringe [EC:2.4.1.222]
K06061 MAML; mastermind
K06053 RBPSUH, RBPJK; recombining binding protein suppressor of hairless
K06054 HES1; hairy and enhancer of split 1
K09087 HES2_6_7; hairy and enhancer of split 2/6/7
K09088 HES3; hairy and enhancer of split 3
K09089 HES4; hairy and enhancer of split 4
K06055 HES5; hairy and enhancer of split 5
K09091 HEY; hairy and enhancer of split related with YRPW motif
|
|
09171 Infectious disease: bacterial
|
|
09174 Infectious disease: parasitic
|
|
09163 Immune disease
|
|
09164 Neurodegenerative disease
|
|
09165 Substance dependence
|
|
09166 Cardiovascular disease
|
05417 Lipid and atherosclerosis [PATH:ko05417]
|
05418 Fluid shear stress and atherosclerosis [PATH:ko05418]
|
05410 Hypertrophic cardiomyopathy [PATH:ko05410]
|
05412 Arrhythmogenic right ventricular cardiomyopathy [PATH:ko05412]
|
05414 Dilated cardiomyopathy [PATH:ko05414]
|
05415 Diabetic cardiomyopathy [PATH:ko05415]
|
K07299 SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K07191 SLC2A4, GLUT4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
K00820 glmS, GFPT; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K12044 TNNI3; troponin I, cardiac muscle
K04962 RYR2; ryanodine receptor 2
K05852 PLN; phospholamban
K05853 ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
K04684 SP1; transcription factor Sp1
K09821 AGT, SERPINA8; angiotensinogen
K01380 REN; renin [EC:3.4.23.15]
K01329 CMA1; chymase [EC:3.4.21.39]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19722 AGER, RAGE; receptor for advanced glycosylation end products
K21421 NOX2, GP91, CYBB; NADPH oxidase 2 [EC:1.-.-.-]
K08011 NCF1, P47PHOX; neutrophil cytosolic factor 1
K08009 CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
K08010 NCF2, P67PHOX; neutrophil cytosolic factor 2
K08012 NCF4, P40PHOX; neutrophil cytosolic factor 4
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K04166 AGTR1; angiotensin II receptor type 1
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K06236 COL1A; collagen type I alpha
K19720 COL3A; collagen type III alpha
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K06259 CD36; CD36 antigen
K07294 NR1C1, PPARA; peroxisome proliferator-activated receptor alpha
K19523 CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]
K00898 PDK2_3_4; pyruvate dehydrogenase kinase 2/3/4 [EC:2.7.11.2]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K17605 PPP2R4, PTPA; serine/threonine-protein phosphatase 2A activator
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K01379 CTSD; cathepsin D [EC:3.4.23.5]
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K08766 CPT2; carnitine O-palmitoyltransferase 2 [EC:2.3.1.21]
K04526 INS; insulin
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K17902 TBC1D4, AS160; TBC1 domain family member 4
K22138 MPC1; mitochondrial pyruvate carrier 1
K22139 MPC2; mitochondrial pyruvate carrier 2
K00161 PDHA, pdhA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
K00162 PDHB, pdhB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
K03878 ND1; NADH-ubiquinone oxidoreductase chain 1 [EC:7.1.1.2]
K03879 ND2; NADH-ubiquinone oxidoreductase chain 2 [EC:7.1.1.2]
K03880 ND3; NADH-ubiquinone oxidoreductase chain 3 [EC:7.1.1.2]
K03881 ND4; NADH-ubiquinone oxidoreductase chain 4 [EC:7.1.1.2]
K03882 ND4L; NADH-ubiquinone oxidoreductase chain 4L [EC:7.1.1.2]
K03883 ND5; NADH-ubiquinone oxidoreductase chain 5 [EC:7.1.1.2]
K03884 ND6; NADH-ubiquinone oxidoreductase chain 6 [EC:7.1.1.2]
K03942 NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
K03943 NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:7.1.1.2]
K03944 NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
K03945 NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1
K03946 NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2
K03947 NDUFA3; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3
K03948 NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K03949 NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5
K03950 NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6
K03951 NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7
K03952 NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8
K03953 NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9
K03954 NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10
K03955 NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1, acyl-carrier protein
K03956 NDUFA11; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11
K11352 NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12
K11353 NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13
K03957 NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
K03959 NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3
K03960 NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4
K03961 NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5
K03962 NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6
K03963 NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7
K03964 NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8
K03965 NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9
K03966 NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10
K11351 NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
K03934 NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:7.1.1.2]
K03935 NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:7.1.1.2]
K03936 NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:7.1.1.2]
K03937 NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
K03938 NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5
K03939 NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6
K03940 NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:7.1.1.2]
K03941 NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:7.1.1.2]
K03967 NDUFC1; NADH dehydrogenase (ubiquinone) 1 subunit C1
K03968 NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
K00234 SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
K00235 SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
K00236 SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
K00237 SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
K00411 UQCRFS1, RIP1, petA; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
K00412 CYTB, petB; ubiquinol-cytochrome c reductase cytochrome b subunit
K00413 CYC1, CYT1, petC; ubiquinol-cytochrome c reductase cytochrome c1 subunit
K00414 QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
K00415 QCR2, UQCRC2; ubiquinol-cytochrome c reductase core subunit 2
K00416 QCR6, UQCRH; ubiquinol-cytochrome c reductase subunit 6
K00417 QCR7, UQCRB; ubiquinol-cytochrome c reductase subunit 7
K00418 QCR8, UQCRQ; ubiquinol-cytochrome c reductase subunit 8
K00419 QCR9, UCRC; ubiquinol-cytochrome c reductase subunit 9
K00420 QCR10, UQCR; ubiquinol-cytochrome c reductase subunit 10
K02262 COX3; cytochrome c oxidase subunit 3
K02256 COX1; cytochrome c oxidase subunit 1 [EC:7.1.1.9]
K02261 COX2; cytochrome c oxidase subunit 2
K02263 COX4; cytochrome c oxidase subunit 4
K02264 COX5A; cytochrome c oxidase subunit 5a
K02265 COX5B; cytochrome c oxidase subunit 5b
K02266 COX6A; cytochrome c oxidase subunit 6a
K02267 COX6B; cytochrome c oxidase subunit 6b
K02268 COX6C; cytochrome c oxidase subunit 6c
K02270 COX7A; cytochrome c oxidase subunit 7a
K02271 COX7B; cytochrome c oxidase subunit 7b
K02272 COX7C; cytochrome c oxidase subunit 7c
K02273 COX8; cytochrome c oxidase subunit 8
K02132 ATPeF1A, ATP5A1, ATP1; F-type H+-transporting ATPase subunit alpha
K02133 ATPeF1B, ATP5B, ATP2; F-type H+-transporting ATPase subunit beta [EC:7.1.2.2]
K02136 ATPeF1G, ATP5C1, ATP3; F-type H+-transporting ATPase subunit gamma
K02134 ATPeF1D, ATP5D, ATP16; F-type H+-transporting ATPase subunit delta
K02135 ATPeF1E, ATP5E, ATP15; F-type H+-transporting ATPase subunit epsilon
K02126 ATPeF0A, MTATP6, ATP6; F-type H+-transporting ATPase subunit a
K02127 ATPeF0B, ATP5F1, ATP4; F-type H+-transporting ATPase subunit b
K02128 ATPeF0C, ATP5G, ATP9; F-type H+-transporting ATPase subunit c
K02138 ATPeF0D, ATP5H, ATP7; F-type H+-transporting ATPase subunit d
K02137 ATPeF0O, ATP5O, ATP5; F-type H+-transporting ATPase subunit O
K02131 ATPeF0F6, ATP5J; F-type H+-transporting ATPase subunit 6
K02125 ATPeF08, MTATP8, ATP8; F-type H+-transporting ATPase subunit 8
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K05863 SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K00134 GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
K00036 G6PD, zwf; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
K00383 GSR, gor; glutathione reductase (NADPH) [EC:1.8.1.7]
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K01283 ACE, CD143; peptidyl-dipeptidase A [EC:3.4.15.1]
|
05416 Viral myocarditis [PATH:ko05416]
|
|
09167 Endocrine and metabolic disease
|
04930 Type II diabetes mellitus [PATH:ko04930]
|
04940 Type I diabetes mellitus [PATH:ko04940]
|
04950 Maturity onset diabetes of the young [PATH:ko04950]
|
04936 Alcoholic liver disease [PATH:ko04936]
|
04932 Non-alcoholic fatty liver disease [PATH:ko04932]
|
04931 Insulin resistance [PATH:ko04931]
|
K04526 INS; insulin
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K05696 PTPN1, PTP1B; tyrosine-protein phosphatase non-receptor type 1 [EC:3.1.3.48]
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K05695 PTPRF, LAR; receptor-type tyrosine-protein phosphatase F [EC:3.1.3.48]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K05405 IL6; interleukin 6
K04692 STAT3; signal transducer and activator of transcription 3
K04696 SOCS3, CIS3; suppressor of cytokine signaling 3
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K17902 TBC1D4, AS160; TBC1 domain family member 4
K07191 SLC2A4, GLUT4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
K14497 PP2C; protein phosphatase 2C [EC:3.1.3.16]
K07198 PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K01946 ACACB; acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K19523 CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]
K09821 AGT, SERPINA8; angiotensinogen
K08745 SLC27A1_4, FATP1_4; solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-]
K08746 SLC27A2, FACVL1, FATP2; solute carrier family 27 (fatty acid transporter), member 2 [EC:6.2.1.- 6.2.1.3]
K08772 SLC27A3, FATP3; solute carrier family 27 (fatty acid transporter), member 3 [EC:6.2.1.-]
K08748 SLC27A5, FATP5; solute carrier family 27 (fatty acid transporter), member 5 [EC:6.2.1.7]
K08749 SLC27A6, FATP6; solute carrier family 27 (fatty acid transporter), member 6
K06259 CD36; CD36 antigen
K18052 PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K17605 PPP2R4, PTPA; serine/threonine-protein phosphatase 2A activator
K07197 SREBP1, SREBF1; sterol regulatory element-binding transcription factor 1
K07187 IRS2; insulin receptor substrate 2
K19518 TRIB3; tribbles homolog 3
K00688 PYG, glgP; glycogen phosphorylase [EC:2.4.1.1]
K07201 FOXO1; forkhead box protein O1
K01596 E4.1.1.32, pckA, PCK; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K07593 SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
K08536 NR1H3, LXRA; liver X receptor alpha
K08535 NR1H2, LXRB; liver X receptor beta
K17962 PPARGC1B, PGC1B; peroxisome proliferator-activated receptor gamma coactivator 1-beta
K09113 MLX; MAX-like protein X
K08765 CPT1A; carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
K11533 fas; fatty acid synthase, bacteria type [EC:2.3.1.-]
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K07202 PPARGC1A, PGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
K07294 NR1C1, PPARA; peroxisome proliferator-activated receptor alpha
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K15719 NCOAT, MGEA5; protein O-GlcNAcase / histone acetyltransferase [EC:3.2.1.169 2.3.1.48]
K09667 OGT; protein O-GlcNAc transferase [EC:2.4.1.255]
K07299 SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K00820 glmS, GFPT; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
K16333 CRTC2, TORC2; CREB-regulated transcription coactivator 2
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
|
04933 AGE-RAGE signaling pathway in diabetic complications [PATH:ko04933]
|
04934 Cushing syndrome [PATH:ko04934]
|
|
09175 Drug resistance: antimicrobial
|
|
09176 Drug resistance: antineoplastic
|
01521 EGFR tyrosine kinase inhibitor resistance [PATH:ko01521]
|
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05455 NRG1; neuregulin 1
K05456 NRG2; neuregulin 2
K05084 ERBB3, HER3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K05460 HGF; hepatocyte growth factor
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K05448 VEGFA; vascular endothelial growth factor A
K05098 KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K18497 FGF2; fibroblast growth factor 2
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05464 GAS6; growth arrest-specific 6
K05115 AXL, UFO; AXL receptor tyrosine kinase [EC:2.7.10.1]
K05405 IL6; interleukin 6
K05055 IL6R, CD126; interleukin 6 receptor
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K09593 GAB1; GRB2-associated-binding protein 1
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02991 RP-S6e, RPS6; small subunit ribosomal protein S6e
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K03259 EIF4E; translation initiation factor 4E
K02158 BAD; Bcl-2-antagonist of cell death
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K09408 FOXO3; forkhead box protein O3
K16341 BCL2L11, BIM; Bcl-2-like protein 11
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K08052 NF1; neurofibromin 1
K02159 BAX; apoptosis regulator BAX
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
|
01524 Platinum drug resistance [PATH:ko01524]
|
01523 Antifolate resistance [PATH:ko01523]
|
01522 Endocrine resistance [PATH:ko01522]
|
|
09180 Brite Hierarchies
|
|
09181 Protein families: metabolism
|
01000 Enzymes [BR:ko01000]
|
01001 Protein kinases [BR:ko01001]
|
01009 Protein phosphatases and associated proteins [BR:ko01009]
|
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K08050 PPP1R1A; protein phosphatase 1 regulatory subunit 1A
K15494 PPP1R1B, DARPP32; protein phosphatase 1 regulatory subunit 1B
K17549 PPP1R1C; protein phosphatase 1 regulatory subunit 1C
K16833 PPP1R2, IPP2; protein phosphatase inhibitor 2
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K17453 PPP1R3F, R3F; protein phosphatase 1 regulatory subunit 3F
K17550 PPP1R7, SDS22; protein phosphatase 1 regulatory subunit 7
K13216 PPP1R8, NIPP1; nuclear inhibitor of protein phosphatase 1 [EC:3.1.4.-]
K17551 PPP1R9; neurabin
K17552 PPP1R10; protein phosphatase 1 regulatory subunit 10
K17553 PPP1R11; protein phosphatase 1 regulatory subunit 11
K06270 PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
K12329 PPP1R12B, MYPT2; protein phosphatase 1 regulatory subunit 12B
K17457 PPP1R12C, MBS85; protein phosphatase 1 regulatory subunit 12C
K16823 TP53BP2, ASPP2; apoptosis-stimulating of p53 protein 2
K17554 PPP1R13B, ASPP1; apoptosis-stimulating of p53 protein 1
K12328 PPP1R14A, CPI17; protein phosphatase 1 regulatory subunit 14A
K17555 PPP1R14B; protein phosphatase 1 regulatory subunit 14B
K17556 PPP1R14C, KEPI; protein phosphatase 1 regulatory subunit 14C
K17557 PPP1R14D, GBPI; protein phosphatase 1 regulatory subunit 14D
K14019 PPP1R15A, GADD34; protein phosphatase 1 regulatory subunit 15A
K17558 PPP1R15B, CREP; protein phosphatase 1 regulatory subunit 15B
K17458 PPP1R16A, MYPT3; protein phosphatase 1 regulatory subunit 16A
K17459 PPP1R16B, TIMAP; protein phosphatase 1 regulatory inhibitor subunit 16B
K08067 PPP1R17, GSBS; protein phosphatase 1 regulatory subunit 17
K17559 PPP1R18; phostensin
K17560 URI1; unconventional prefoldin RPB5 interactor 1
K17561 CCDC8; coiled-coil domain-containing protein 8
K17562 PPP1R21, CCDC128, KLRAQ1; protein phosphatase 1 regulatory subunit 21
K17563 CHCHD3; MICOS complex subunit MIC19
K17564 CHCHD6; MICOS complex subunit MIC25
K17495 CSMD; CUB and sushi domain-containing protein
K14806 DDX31, DBP7; ATP-dependent RNA helicase DDX31/DBP7 [EC:5.6.2.7]
K17565 PPP1R26; protein phosphatase 1 regulatory subunit 26
K17566 PPP1R27; protein phosphatase 1 regulatory subunit 27
K17567 ELFN1; protein phosphatase 1 regulatory subunit 28
K17568 ELFN2; protein phosphatase 1 regulatory subunit 29
K17569 GPATCH2; G patch domain-containing protein 2
K17570 HYDIN; hydrocephalus-inducing protein
K17571 PPP1R32; protein phosphatase 1 regulatory subunit 32
K17572 ARFGEF3, KEPI; brefeldin A-inhibited guanine nucleotide-exchange protein 3
K17573 LKAP, MARF1; meiosis arrest female protein 1
K17574 PPP1R35; protein phosphatase 1 regulatory subunit 35
K17575 PPP1R36; protein phosphatase 1 regulatory subunit 36
K17576 PPP1R37, LRRC68; protein phosphatase 1 regulatory subunit 37
K17577 SH2D4A; SH2 domain-containing protein 4A
K12171 SH3RF, POSH; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]
K12018 TRIM42; tripartite motif-containing protein 42
K17578 ZCCHC9; zinc finger CCHC domain-containing protein 9
K17579 PPP1R42, LRRC67; protein phosphatase 1 regulatory subunit 42
K16518 AKAP1; A-kinase anchor protein 1, mitochondrial
K16527 AKAP11; A-kinase anchor protein 11
K16551 AKAP9, AKAP350; A-kinase anchor protein 9
K02085 APC; adenomatosis polyposis coli protein
K11481 AURKA; aurora kinase A [EC:2.7.11.1]
K11479 AURKB; aurora kinase B [EC:2.7.11.1]
K02157 AXIN1; axin 1
K02161 BCL2; apoptosis regulator Bcl-2
K02163 BCLW; apoptosis regulator BCL-W
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K17580 CASC1; cancer susceptibility candidate protein 1
K11542 CASC5, KNL1; protein CASC5
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02186 CASP2; caspase 2 [EC:3.4.22.55]
K12075 DLG2; discs large protein 2
K21098 DLG3; discs large protein 3
K13099 CD2BP2, PPP1R59; CD2 antigen cytoplasmic tail-binding protein 2
K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
K11498 CENPE, KIF10; centromeric protein E
K16725 CEP192; centrosomal protein CEP192
K05016 CLCN7; chloride channel 7
K17581 CNST; consortin
K15502 ANKRD28; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A
K10642 DZIP3; E3 ubiquitin-protein ligase DZIP3 [EC:2.3.2.27]
K03238 EIF2S2; translation initiation factor 2 subunit 2
K15183 ELL; RNA polymerase II elongation factor ELL
K04679 MADHIP, SARA; MAD, mothers against decapentaplegic interacting protein
K11248 SH3GLB1; endophilin-B1
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K17494 CSRNP; cysteine/serine-rich nuclear protein
K08889 FER, TYK3; tyrosine-protein kinase Fer [EC:2.7.10.2]
K17477 FARP1; FERM, RhoGEF and pleckstrin domain-containing protein 1
K17478 FKBP15, WAFL; FK506-binding protein 15
K03504 POLD3; DNA polymerase delta subunit 3
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K04315 GPR12; G protein-coupled receptor 12
K17479 GRXCR1; glutaredoxin domain-containing cysteine-rich protein 1
K14966 HCFC1; host cell factor 1
K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]
K09220 IKZF, ZNFN1A; IKAROS family zinc finger protein
K06476 ITGA2B, CD41; integrin alpha 2B
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K01251 AHCY, ahcY; adenosylhomocysteinase [EC:3.13.2.1]
K11446 KDM5, JARID1; [histone H3]-trimethyl-L-lysine4 demethylase [EC:1.14.11.67]
K04879 KCNA6, KV1.6; potassium voltage-gated channel Shaker-related subfamily A member 6
K04920 KCNK10, K2P10.1; potassium channel subfamily K member 10
K08898 LMTK2; lemur tyrosine kinase 2 [EC:2.7.10.1]
K02932 RP-L5e, RPL5; large subunit ribosomal protein L5e
K17480 AATK, LMTK1; lemur tyrosine kinase 1 [EC:2.7.10.1]
K08899 LMTK3; lemur tyrosine kinase 3 [EC:2.7.10.1]
K10429 MAP1; microtubule-associated protein 1
K02210 MCM7, CDC47; DNA replication licensing factor MCM7 [EC:5.6.2.3]
K04603 GRM1; metabotropic glutamate receptor 1
K04608 GRM6; metabotropic glutamate receptor 6
K04609 GRM7; metabotropic glutamate receptor 7
K04610 GRM8; metabotropic glutamate receptor 8
K17582 MKI67; antigen KI-67
K14559 MPP10; U3 small nucleolar RNA-associated protein MPP10
K10356 MYO1; myosin I
K17481 MYO16; myosin XVI
K04650 NCOR1, N-CoR; nuclear receptor co-repressor 1
K20872 NEK2; serine/threonine-protein kinase Nek2 [EC:2.7.11.1]
K04572 NEFL, NF-L; neurofilament light polypeptide
K17493 CAMSAP; calmodulin-regulated spectrin-associated protein
K05742 SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
K10951 SLC12A2, NKCC1; solute carrier family 12 (sodium/potassium/chloride transporter), member 2
K17583 NOM1; nucleolar MIF4G domain-containing protein 1
K06088 OCLN; occludin
K04256 OPN3; c-opsin
K02607 ORC5; origin recognition complex subunit 5
K04237 PARD3; partitioning defective protein 3
K17584 PCIF1; phosphorylated CTD-interacting factor 1
K00850 pfkA, PFK; 6-phosphofructokinase 1 [EC:2.7.1.11]
K17594 PHACTR; phosphatase and actin regulator
K17586 PHRF1; PHD and RING finger domain-containing protein 1
K06633 PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1]
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
K17587 TMEM225; transmembrane protein 225
K17588 PREX2; phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein
K15375 PLCL1, PRIP; inactive phospholipase C-like protein 1
K16498 PCDHD1; protocadherin delta 1
K13219 SFPQ, PSF; splicing factor, proline- and glutamine-rich
K06618 RB1; retinoblastoma-associated protein
K17589 RB1CC1; RB1-inducible coiled-coil protein 1
K13192 RBM26; RNA-binding protein 26
K17590 CDCA2; cell division cycle-associated protein 2
K17591 RIMBP2; RIMS-binding protein 2
K16550 RPGRIP1L; protein fantom
K14849 RRP1; ribosomal RNA-processing protein 1
K04961 RYR1; ryanodine receptor 1
K17592 SACS; sacsin
K17593 ANKRD42, SARP; ankyrin repeat domain-containing protein 42
K12866 WBP11, NPWBP; WW domain-binding protein 11
K11648 SMARCB1, SNF5, INI1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
K13871 SLC7A14; solute carrier family 7 (cationic amino acid transporter), member 14
K17595 SPATA2; spermatogenesis-associated protein 2
K17596 SPOCD1; SPOC domain-containing protein 1
K04703 SPRED; sprouty-related, EVH1 domain-containing protein
K17482 SPZ1; spermatogenic leucine zipper protein 1
K12900 SRSF10, FUSIP1; serine/arginine-rich splicing factor 10
K17597 STAU; double-stranded RNA-binding protein Staufen
K17598 SYTL; synaptotagmin-like protein
K04380 MAPT, TAU; microtubule-associated protein tau
K17599 TMEM132; transmembrane protein 132
K12897 TRA2; transformer-2 protein
K11796 TRPC4AP; Trpc4-associated protein
K04968 TRPC5; transient receptor potential cation channel subfamily C member 5
K07207 TSC2; tuberous sclerosis 2
K16492 TSKS; testis-specific serine kinase substrate
K17492 UBN; ubinuclein
K08539 VDR, NR1I1; vitamin D3 receptor
K17600 VPS54; vacuolar protein sorting-associated protein 54
K17601 WDR81; WD repeat-containing protein 81
K08867 WNK, PRKWNK; WNK lysine deficient protein kinase [EC:2.7.11.1]
K17602 YLPM1; YLP motif-containing protein 1
K10510 ZBTB38; zinc finger and BTB domain-containing protein 38
K17603 ZFYVE1; zinc finger FYVE domain-containing protein 1
K17604 ZSWIM3; zinc finger SWIM domain-containing protein 3
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K17605 PPP2R4, PTPA; serine/threonine-protein phosphatase 2A activator
K17606 IGBP1, TAP42; immunoglobulin-binding protein 1
K17607 TIPRL, TIP41; type 2A phosphatase activator TIP41
K17608 STRN1_3_4; striatin 1/3/4
K17609 NXN; nucleoredoxin [EC:1.8.1.8]
K18203 LCMT1; [phosphatase 2A protein]-leucine-carboxy methyltransferase [EC:2.1.1.233]
K27491 ENSA, ARPP19; endosulfine family protein
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K21814 CPPED1; serine/threonine-protein phosphatase CPPED1 [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K02183 CALM; calmodulin
K17610 CHP, CHP1; calcineurin B homologous protein 1
K17611 CHP2; calcineurin B homologous protein 2
K17612 TESC, CHP3; calcineurin B homologous protein 3
K17613 CABIN1; calcineurin-binding protein cabin-1
K16522 AKAP5; A-kinase anchor protein 5
K09574 FKBP8; FK506-binding protein 8 [EC:5.2.1.8]
K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2
K17491 SMEK, PPP4R3; protein phosphatase 4 regulatory subunit 3
K15426 PPP4R4; serine/threonine-protein phosphatase 4 regulatory subunit 4
K04460 PPP5C; serine/threonine-protein phosphatase 5 [EC:3.1.3.16]
K03350 APC3, CDC27; anaphase-promoting complex subunit 3
K03353 APC6, CDC16; anaphase-promoting complex subunit 6
K04079 HSP90A, htpG; molecular chaperone HtpG
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
K15427 SIT4, PPH1; serine/threonine-protein phosphatase PP1-1 [EC:3.1.3.16]
K17615 PPG1; serine/threonine-protein phosphatase PPG1 [EC:3.1.3.16]
K15499 PPP6R1, SAPS1; serine/threonine-protein phosphatase 6 regulatory subunit 1
K15500 PPP6R2, SAPS2; serine/threonine-protein phosphatase 6 regulatory subunit 2
K15501 PPP6R3, SAPS3; serine/threonine-protein phosphatase 6 regulatory subunit 3
K15503 ANKRD44; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B
K15504 ANKRD52; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C
K13807 PPEF, PPP7C; serine/threonine-protein phosphatase with EF-hands [EC:3.1.3.16]
K04457 PPM1A, PP2CA; protein phosphatase 1A [EC:3.1.3.16]
K04461 PPM1B, PP2CB; protein phosphatase 1B [EC:3.1.3.16]
K17499 PPM1G, PP2CG; protein phosphatase 1G [EC:3.1.3.16]
K17500 ILKAP; integrin-linked kinase-associated serine/threonine phosphatase 2C [EC:3.1.3.16]
K10147 PPM1D, WIP1; protein phosphatase 1D [EC:3.1.3.16]
K17501 PPM1E, POPX1; protein phosphatase 1E [EC:3.1.3.16]
K17502 PPM1F, POPX2; protein phosphatase 1F [EC:3.1.3.16]
K17503 PPM1H, ARHCL1; protein phosphatase 1H [EC:3.1.3.16]
K17504 PPM1J, PP2CZ; protein phosphatase 1J [EC:3.1.3.16]
K17505 PPM1K, PP2CM; protein phosphatase 1K [EC:3.1.3.16]
K17506 PPM1L, PP2CE; protein phosphatase 1L [EC:3.1.3.16]
K17507 PPM1M, PP2CE; protein phosphatase 1M [EC:3.1.3.16]
K19790 PPM1N; protein phosphatase 1N [EC:3.1.3.16]
K16340 PHLPP; PH domain and leucine-rich repeat-containing protein phosphatase [EC:3.1.3.16]
K19704 PTC1; protein phosphatase PTC1 [EC:3.1.3.16]
K14803 PTC2_3; protein phosphatase PTC2/3 [EC:3.1.3.16]
K19705 PTC4; protein phosphatase PTC4 [EC:3.1.3.16]
K19708 PTC6, AUP1; protein phosphatase PTC6 [EC:3.1.3.16 3.1.3.43]
K17508 PTC7, PPTC7; protein phosphatase PTC7 [EC:3.1.3.16]
K20074 prpC, phpP; PPM family protein phosphatase [EC:3.1.3.16]
K01102 PDP; pyruvate dehydrogenase phosphatase [EC:3.1.3.43]
K17509 PDPR; pyruvate dehydrogenase phosphatase regulatory subunit
K18032 PTPRA; receptor-type tyrosine-protein phosphatase A [EC:3.1.3.48]
K05694 PTPRB, PTPB; receptor-type tyrosine-protein phosphatase beta [EC:3.1.3.48]
K06478 PTPRC, CD45; receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48]
K06777 PTPRD; receptor-type tyrosine-protein phosphatase delta [EC:3.1.3.48]
K18033 PTPRE; receptor-type tyrosine-protein phosphatase epsilon [EC:3.1.3.48]
K05695 PTPRF, LAR; receptor-type tyrosine-protein phosphatase F [EC:3.1.3.48]
K16667 PTPRG; receptor-type tyrosine-protein phosphatase gamma [EC:3.1.3.48]
K18034 PTPRH, SAP1; receptor-type tyrosine-protein phosphatase H [EC:3.1.3.48]
K05698 PTPRJ, DEP1, CD148; receptor-type tyrosine-protein phosphatase eta [EC:3.1.3.48]
K06776 PTPRK; receptor-type tyrosine-protein phosphatase kappa [EC:3.1.3.48]
K05693 PTPRM; receptor-type tyrosine-protein phosphatase mu [EC:3.1.3.48]
K07817 PTPRN; receptor-type tyrosine-protein phosphatase N [EC:3.1.3.48]
K18035 PTPRO; receptor-type tyrosine-protein phosphatase O [EC:3.1.3.48]
K16910 PTPRQ; receptor-type tyrosine-protein phosphatase Q [EC:3.1.3.48]
K04458 PTPRR; receptor-type tyrosine-protein phosphatase R [EC:3.1.3.48]
K06778 PTPRS; receptor-type tyrosine-protein phosphatase S [EC:3.1.3.48]
K13297 PTPRT; receptor-type tyrosine-protein phosphatase T [EC:3.1.3.48]
K16662 PTPRU; receptor-type tyrosine-protein phosphatase U [EC:3.1.3.48]
K18036 PTPRV, ESP; receptor-type tyrosine-protein phosphatase V [EC:3.1.3.48]
K08114 PTPRZ; receptor-type tyrosine-protein phosphatase zeta [EC:3.1.3.48]
K05696 PTPN1, PTP1B; tyrosine-protein phosphatase non-receptor type 1 [EC:3.1.3.48]
K18026 PTPN2, PTPT; tyrosine-protein phosphatase non-receptor type 2 [EC:3.1.3.48]
K18027 PTPN3, PTPH1; tyrosine-protein phosphatase non-receptor type 3 [EC:3.1.3.48]
K18037 PTPN4, MEG; tyrosine-protein phosphatase non-receptor type 4 [EC:3.1.3.48]
K18018 PTPN5; tyrosine-protein phosphatase non-receptor type 5 [EC:3.1.3.48]
K05697 PTPN6, SHP1; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
K18019 PTPN7; tyrosine-protein phosphatase non-receptor type 7 [EC:3.1.3.48]
K18038 PTPN9, MEG2; tyrosine-protein phosphatase non-receptor type 9 [EC:3.1.3.48]
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K18024 PTPN12_18_22; tyrosine-protein phosphatase non-receptor type 12/18/22 [EC:3.1.3.48]
K02374 PTPN13, FAP-1; tyrosine-protein phosphatase non-receptor type 13
K18025 PTPN14_21; tyrosine-protein phosphatase non-receptor type 14/21 [EC:3.1.3.48]
K18039 PTPN20; tyrosine-protein phosphatase non-receptor type 20 [EC:3.1.3.48]
K18040 PTPN23; tyrosine-protein phosphatase non-receptor type 23 [EC:3.1.3.48]
K20220 PTP-ER; tyrosine-protein phosphatase ERK [EC:3.1.3.48]
K19806 PTP2_3; tyrosine-protein phosphatase 2/3 [EC:3.1.3.48]
K21278 DUSP1; dual specificity protein phosphatase 1 [EC:3.1.3.16 3.1.3.48]
K04459 DUSP, MKP; dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
K21946 DUSP6; dual specificity phosphatase 6 [EC:3.1.3.16 3.1.3.48]
K18498 DUSP9, MKP4; dual specificity phosphatase 9 [EC:3.1.3.16 3.1.3.48]
K20216 DUSP10; dual specificity phosphatase 10 [EC:3.1.3.16 3.1.3.48]
K11240 MSG5; tyrosine-protein phosphatase MSG5 [EC:3.1.3.48]
K19812 SDP1; dual-specificity protein phosphatase SDP1 [EC:3.1.3.48]
K05766 SSH; protein phosphatase slingshot [EC:3.1.3.16 3.1.3.48]
K18041 PTP4A; protein tyrosine phosphatase type IVA [EC:3.1.3.48]
K17614 DUSP3, VHR; dual specificity phosphatase 3 [EC:3.1.3.16 3.1.3.48]
K14819 DUSP12, YVH1; dual specificity phosphatase 12 [EC:3.1.3.16 3.1.3.48]
K14165 K14165; atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48]
K18042 STYX; serine/threonine/tyrosine-interacting protein
K20551 MKP2; dual specificity protein phosphatase 1B [EC:3.1.3.16 3.1.3.48]
K18043 OCA1; tyrosine-protein phosphatase OCA1 [EC:3.1.3.48]
K18044 OCA2; tyrosine-protein phosphatase-like protein OCA2
K18045 SIW14, OCA3; tyrosine-protein phosphatase SIW14 [EC:3.1.3.48]
K18046 OCA6; tyrosine-protein phosphatase OCA6 [EC:3.1.3.48]
K06639 CDC14; cell division cycle 14 [EC:3.1.3.16 3.1.3.48]
K14167 CDKN3, KAP; cyclin-dependent kinase inhibitor 3 [EC:3.1.3.16 3.1.3.48]
K18078 PTPDC1; protein tyrosine phosphatase domain-containing protein 1 [EC:3.1.3.-]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K18079 TPTE, TPIP; PTEN homologous phosphatase
K18080 TNS; tensin
K01108 MTM1; myotubularin [EC:3.1.3.64 3.1.3.95]
K18081 MTMR1_2; myotubularin-related protein 1/2 [EC:3.1.3.64 3.1.3.95]
K18082 MTMR3_4, ZFYVE10_11; myotubularin-related protein 3/4 [EC:3.1.3.48 3.1.3.64 3.1.3.95]
K18061 SBF1_2, MTMR5_13; myotubularin-related protein 5/13
K18083 MTMR6_7_8; myotubularin-related protein 6/7/8 [EC:3.1.3.64 3.1.3.95]
K18084 MTMR9; myotubularin-related protein 9
K18085 MTMR10_11_12; myotubularin-related protein 10/11/12
K18086 MTMR14; myotubularin-related protein 14 [EC:3.1.3.64 3.1.3.95]
K18993 UBASH3, STS; ubiquitin-associated and SH3 domain-containing protein [EC:3.1.3.48]
K14394 ACP1; low molecular weight phosphotyrosine protein phosphatase [EC:3.1.3.2 3.1.3.48]
K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
K18065 CDC25; Cdc25 family phosphatase [EC:3.1.3.48 1.20.4.1]
K02555 MIH1; M-phase inducer tyrosine phosphatase [EC:3.1.3.48]
K15732 CTDP1, FCP1; RNA polymerase II subunit A C-terminal domain phosphatase [EC:3.1.3.16]
K15731 CTDSP; carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase [EC:3.1.3.16]
K17616 CTDSPL2; CTD small phosphatase-like protein 2 [EC:3.1.3.-]
K17617 CTDNEP1, DULLARD, NEM1; CTD nuclear envelope phosphatase 1 [EC:3.1.3.16]
K18998 CPL1_2; RNA polymerase II C-terminal domain phosphatase-like 1/2 [EC:3.1.3.16]
K18999 CPL3_4; RNA polymerase II C-terminal domain phosphatase-like 3/4 [EC:3.1.3.16]
K17618 UBLCP1; ubiquitin-like domain-containing CTD phosphatase 1 [EC:3.1.3.16]
K20827 RPAP2; RNA polymerase II-associated protein 2 [EC:3.1.3.16]
K17619 MDP1; magnesium-dependent phosphatase 1 [EC:3.1.3.48 3.1.3.-]
K15616 EYA1; eyes absent homolog 1 [EC:3.1.3.48]
K17620 EYA2; eyes absent homolog 2 [EC:3.1.3.48]
K17621 EYA3; eyes absent homolog 3 [EC:3.1.3.48]
K17622 EYA4; eyes absent homolog 4 [EC:3.1.3.48]
K07758 PDXP; pyridoxal phosphatase [EC:3.1.3.74]
K19269 PGP, PGLP; phosphoglycolate phosphatase [EC:3.1.3.18 3.1.3.48]
K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
K08726 EPHX2; soluble epoxide hydrolase / lipid-phosphate phosphatase [EC:3.3.2.10 3.1.3.76]
K01079 serB, PSPH; phosphoserine phosphatase [EC:3.1.3.3]
K06124 PHOSPHO1; phosphoethanolamine/phosphocholine phosphatase [EC:3.1.3.75]
K13248 PHOSPHO2; pyridoxal phosphate phosphatase PHOSPHO2 [EC:3.1.3.74]
K17623 PUDP, HDHD1; pseudouridine 5'-phosphatase [EC:3.1.3.96]
K01097 NANP; N-acylneuraminate-9-phosphatase [EC:3.1.3.29]
K11725 LHPP; phospholysine phosphohistidine inorganic pyrophosphate phosphatase [EC:3.6.1.1 3.1.3.-]
K15728 LPIN; phosphatidate phosphatase LPIN [EC:3.1.3.4]
|
01002 Peptidases and inhibitors [BR:ko01002]
|
01003 Glycosyltransferases [BR:ko01003]
|
01005 Lipopolysaccharide biosynthesis proteins [BR:ko01005]
|
01011 Peptidoglycan biosynthesis and degradation proteins [BR:ko01011]
|
01004 Lipid biosynthesis proteins [BR:ko01004]
|
01008 Polyketide biosynthesis proteins [BR:ko01008]
|
01006 Prenyltransferases [BR:ko01006]
|
01007 Amino acid related enzymes [BR:ko01007]
|
00199 Cytochrome P450 [BR:ko00199]
|
00194 Photosynthesis proteins [BR:ko00194]
|
|
09182 Protein families: genetic information processing
|
|
09183 Protein families: signaling and cellular processes
|
|
09185 Viral protein families
|
|
09184 RNA family
|
|
09190 Not Included in Pathway or Brite
|
KEGG Orthology (KO)