KEGG   ORTHOLOGY: K05858
Entry
K05858                      KO                                     
Symbol
PLCB
Name
phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Pathway
map00562  Inositol phosphate metabolism
map01100  Metabolic pathways
map04015  Rap1 signaling pathway
map04020  Calcium signaling pathway
map04022  cGMP-PKG signaling pathway
map04062  Chemokine signaling pathway
map04070  Phosphatidylinositol signaling system
map04071  Sphingolipid signaling pathway
map04072  Phospholipase D signaling pathway
map04261  Adrenergic signaling in cardiomyocytes
map04270  Vascular smooth muscle contraction
map04310  Wnt signaling pathway
map04361  Axon regeneration
map04371  Apelin signaling pathway
map04540  Gap junction
map04611  Platelet activation
map04613  Neutrophil extracellular trap formation
map04621  NOD-like receptor signaling pathway
map04713  Circadian entrainment
map04720  Long-term potentiation
map04723  Retrograde endocannabinoid signaling
map04724  Glutamatergic synapse
map04725  Cholinergic synapse
map04726  Serotonergic synapse
map04728  Dopaminergic synapse
map04730  Long-term depression
map04742  Taste transduction
map04745  Phototransduction - fly
map04750  Inflammatory mediator regulation of TRP channels
map04911  Insulin secretion
map04912  GnRH signaling pathway
map04915  Estrogen signaling pathway
map04916  Melanogenesis
map04918  Thyroid hormone synthesis
map04919  Thyroid hormone signaling pathway
map04921  Oxytocin signaling pathway
map04922  Glucagon signaling pathway
map04924  Renin secretion
map04925  Aldosterone synthesis and secretion
map04926  Relaxin signaling pathway
map04927  Cortisol synthesis and secretion
map04928  Parathyroid hormone synthesis, secretion and action
map04929  GnRH secretion
map04933  AGE-RAGE signaling pathway in diabetic complications
map04934  Cushing syndrome
map04935  Growth hormone synthesis, secretion and action
map04961  Endocrine and other factor-regulated calcium reabsorption
map04970  Salivary secretion
map04971  Gastric acid secretion
map04972  Pancreatic secretion
map04973  Carbohydrate digestion and absorption
map05010  Alzheimer disease
map05016  Huntington disease
map05017  Spinocerebellar ataxia
map05022  Pathways of neurodegeneration - multiple diseases
map05131  Shigellosis
map05142  Chagas disease
map05143  African trypanosomiasis
map05146  Amoebiasis
map05163  Human cytomegalovirus infection
map05200  Pathways in cancer
map05415  Diabetic cardiomyopathy
map05417  Lipid and atherosclerosis
Module
M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Reaction
R03332  1-phosphatidyl-D-myo-inositol inositolphosphohydrolase
R03435  1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase
R10952  1-phosphatidyl-1D-myo-inositol-4-phosphate inositolbisphosphohydrolase
Disease
H00606  Early infantile epileptic encephalopathy
H01815  Malignant migrating partial seizures in infancy
H01884  Auriculocondylar syndrome
H02185  Spondylometaphyseal dysplasia
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   04310 Wnt signaling pathway
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   04371 Apelin signaling pathway
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   04020 Calcium signaling pathway
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   04070 Phosphatidylinositol signaling system
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   04072 Phospholipase D signaling pathway
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   04071 Sphingolipid signaling pathway
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   04022 cGMP-PKG signaling pathway
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   04613 Neutrophil extracellular trap formation
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   04621 NOD-like receptor signaling pathway
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   04062 Chemokine signaling pathway
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
  09152 Endocrine system
   04911 Insulin secretion
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   04922 Glucagon signaling pathway
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   04929 GnRH secretion
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   04912 GnRH signaling pathway
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   04915 Estrogen signaling pathway
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   04921 Oxytocin signaling pathway
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   04926 Relaxin signaling pathway
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   04935 Growth hormone synthesis, secretion and action
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   04918 Thyroid hormone synthesis
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   04919 Thyroid hormone signaling pathway
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   04928 Parathyroid hormone synthesis, secretion and action
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   04916 Melanogenesis
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   04924 Renin secretion
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   04925 Aldosterone synthesis and secretion
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   04927 Cortisol synthesis and secretion
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   04270 Vascular smooth muscle contraction
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
  09154 Digestive system
   04970 Salivary secretion
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   04971 Gastric acid secretion
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   04972 Pancreatic secretion
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   04973 Carbohydrate digestion and absorption
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
  09156 Nervous system
   04724 Glutamatergic synapse
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   04725 Cholinergic synapse
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   04728 Dopaminergic synapse
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   04726 Serotonergic synapse
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   04720 Long-term potentiation
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   04730 Long-term depression
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   04723 Retrograde endocannabinoid signaling
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
  09157 Sensory system
   04745 Phototransduction - fly
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   04742 Taste transduction
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   04750 Inflammatory mediator regulation of TRP channels
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
  09158 Development and regeneration
   04361 Axon regeneration
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
  09159 Environmental adaptation
   04713 Circadian entrainment
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   05142 Chagas disease
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   05143 African trypanosomiasis
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   05016 Huntington disease
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   05017 Spinocerebellar ataxia
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   05022 Pathways of neurodegeneration - multiple diseases
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   05415 Diabetic cardiomyopathy
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
   04934 Cushing syndrome
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     K05858  PLCB; phosphatidylinositol phospholipase C, beta
Membrane trafficking [BR:ko04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
 Endocytosis
  Macropinocytosis
   Phospholipase C
    K05858  PLCB; phosphatidylinositol phospholipase C, beta
Other DBs
GO: 0004435
Genes
HSA: 23236(PLCB1) 5330(PLCB2) 5331(PLCB3) 5332(PLCB4)
PTR: 451290(PLCB3) 453330(PLCB2) 458093(PLCB4) 469875(PLCB1)
PPS: 100969344(PLCB2) 100969660(PLCB1) 100978643(PLCB4) 100987524(PLCB3)
GGO: 101129357(PLCB3) 101140350(PLCB2) 101153613(PLCB1) 101154323(PLCB4)
PON: 100434502(PLCB1) 100458716(PLCB2) 100460060(PLCB3) 100461961(PLCB4)
PPYG: 129008805(PLCB3) 129014406(PLCB2) 129021599(PLCB4) 129022097(PLCB1)
NLE: 100597115(PLCB1) 100600507(PLCB4) 100600865(PLCB3) 100606558(PLCB2)
HMH: 116461202(PLCB4) 116461370(PLCB1) 116468938(PLCB3) 116481969(PLCB2)
SSYN: 129460108(PLCB3) 129474256(PLCB1) 129474865(PLCB4) 129482631(PLCB2)
MCC: 701951(PLCB2) 717764(PLCB3) 718387(PLCB1) 718418(PLCB4)
MCF: 101925220(PLCB4) 102123165(PLCB3) 102136896(PLCB2) 102140615(PLCB1)
MNI: 105469511(PLCB3) 105481530(PLCB4) 105481533(PLCB1) 105492354(PLCB2)
CSAB: 103233299(PLCB3) 103245842(PLCB2) 103246591(PLCB4) 103246657(PLCB1)
CATY: 105574260(PLCB2) 105577494(PLCB3) 105582089(PLCB4) 105582092(PLCB1)
PANU: 100998763(PLCB1) 100999120(PLCB4) 101010000(PLCB2) 101012903(PLCB3)
TGE: 112607332(PLCB3) 112627584(PLCB2) 112633067(PLCB1) 112633206(PLCB4)
MLEU: 105546224(PLCB2) 105549095(PLCB3) 105552818(PLCB1) 105553023(PLCB4)
RRO: 104655777(PLCB4) 104659669(PLCB2) 104668296(PLCB1) 104673127(PLCB3)
RBB: 108526885(PLCB2) 108527553(PLCB1) 108527564(PLCB4) 108542252(PLCB3)
TFN: 117068469(PLCB4) 117068471(PLCB1) 117070870(PLCB2) 117080608(PLCB3)
PTEH: 111522292(PLCB3) 111524236(PLCB2) 111546451(PLCB4) 111546452(PLCB1)
CANG: 105505028(PLCB2) 105510999(PLCB1) 105512214(PLCB3) 105516588(PLCB4)
CJC: 100386921(PLCB2) 100400803(PLCB3) 100409716(PLCB1) 100410075(PLCB4)
SBQ: 101029401(PLCB3) 101046851(PLCB4) 101047168(PLCB1) 101052271(PLCB2)
CIMI: 108300913(PLCB1) 108300966(PLCB4) 108306142(PLCB2) 108310295(PLCB3)
ANAN: 105719088(PLCB1) 105719371(PLCB4) 105724146(PLCB2) 105724477(PLCB3)
CSYR: 103257479(PLCB1) 103261218(PLCB4) 103272341(PLCB2) 103275147(PLCB3)
MMUR: 105861219(PLCB1) 105872433(PLCB2) 105878468(PLCB3) 105880040(PLCB4)
LCAT: 123622057(PLCB4) 123622065(PLCB1) 123624366(PLCB2) 123641430(PLCB3)
PCOQ: 105806167(PLCB1) 105806182(PLCB4) 105814456(PLCB2) 105827297(PLCB3)
OGA: 100951857(PLCB4) 100953462(PLCB2) 100966029(PLCB1) 100966182(PLCB3)
MMU: 18795(Plcb1) 18796(Plcb2) 18797(Plcb3) 18798(Plcb4)
MCAL: 110285320(Plcb3) 110286326(Plcb2) 110290514(Plcb4) 110308867(Plcb1)
MPAH: 110317815(Plcb4) 110318415(Plcb2) 110319646(Plcb1) 110336671(Plcb3)
RNO: 24654(Plcb1) 25031(Plcb4) 29322(Plcb3) 85240(Plcb2)
MCOC: 116090695(Plcb2) 116090998(Plcb1) 116090999(Plcb4) 116103465(Plcb3)
ANU: 117703017(Plcb4) 117703351(Plcb1) 117703529(Plcb2) 117712005(Plcb3)
MUN: 110550598(Plcb2) 110551595(Plcb3) 110555720(Plcb1) 110563159
CGE: 100751979(Plcb1) 100760134(Plcb3) 100760731(Plcb2) 100770957(Plcb4)
MAUA: 101830949(Plcb1) 101834401(Plcb3) 101834708(Plcb4) 101842030(Plcb2)
PROB: 127221390(Plcb4) 127221392(Plcb1) 127221647(Plcb2) 127228774(Plcb3)
PLEU: 114680674(Plcb3) 114703666(Plcb4) 114703672(Plcb1) 114705921(Plcb2)
MORG: 121454560(Plcb3) 121460033(Plcb1) 121460541(Plcb4) 121465646(Plcb2)
AAMP: 119814344(Plcb2) 119814366(Plcb1) 119814933(Plcb4) 119824882(Plcb3)
NGI: 103735195(Plcb1) 103738797(Plcb3) 103741502(Plcb2)
HGL: 101696454(Plcb4) 101697744(Plcb3) 101708380(Plcb2) 101725860(Plcb1)
CPOC: 100714143(Plcb2) 100727662(Plcb3) 100729394(Plcb4) 100730572(Plcb1)
CCAN: 109683285(Plcb3) 109684223(Plcb1) 109701244(Plcb2)
DORD: 105981148(Plcb2) 105981715(Plcb1) 105981749(Plcb4) 105989246(Plcb3)
DSP: 122105124(Plcb3) 122114401(Plcb2) 122120299(Plcb1) 122120360(Plcb4)
PLOP: 125340765(Plcb2) 125353265(Plcb4) 125353267(Plcb1) 125362680(Plcb3)
MMMA: 107135966(Plcb3) 107138232(Plcb2) 107145453(Plcb1) 107145524
OPI: 101520538(PLCB3) 101524349(PLCB1) 101524739(PLCB4) 101529337(PLCB2)
TUP: 102472532(PLCB3) 102476196(PLCB4) 102477438(PLCB1) 102492903(PLCB2)
GVR: 103586228(PLCB3) 103588545 103591300 103596484(PLCB1) 103606378(PLCB4)
CFA: 100856190(PLCB2) 476034(PLCB3) 477160(PLCB4) 485773(PLCB1)
CLUD: 112659377(PLCB3) 112673608(PLCB4) 112673609(PLCB1) 112676127(PLCB2)
VVP: 112919942(PLCB2) 112924037(PLCB3) 112930053(PLCB4) 112930054(PLCB1)
VLG: 121472045(PLCB3) 121476506(PLCB2) 121477755(PLCB1) 121478236(PLCB4)
NPO: 129496894(PLCB1) 129497646(PLCB4) 129500550(PLCB3) 129504276(PLCB2)
AML: 100465232(PLCB3) 100474779(PLCB2) 100480603(PLCB4) 100481755(PLCB1)
UMR: 103673552 103674425(PLCB1) 103674426(PLCB4) 103679549(PLCB3) 121099746
UAH: 113242038(PLCB2) 113244175(PLCB3) 113258243(PLCB1) 113258346(PLCB4)
UAR: 123778465(PLCB3) 123799710(PLCB1) 123799736(PLCB4) 123804253(PLCB2)
MPUF: 101673753(PLCB2) 101678347(PLCB1) 101679345(PLCB4) 101687768(PLCB3)
MNP: 131999626(PLCB2) 132019538(PLCB3) 132021732(PLCB4) 132021734(PLCB1)
MLK: 131808069(PLCB1) 131808080(PLCB4) 131814631(PLCB3) 131836105(PLCB2)
NVS: 122913059(PLCB3) 122916255(PLCB1) 122916256(PLCB4)
ORO: 101375710(PLCB3) 101379806(PLCB2) 101386162(PLCB4) 101386750(PLCB1)
EJU: 114216386(PLCB1) 114216392(PLCB4) 114220426(PLCB3) 114221305(PLCB2)
ZCA: 113909205(PLCB2) 113915286(PLCB3) 113937245(PLCB1) 113937989(PLCB4)
MLX: 118003092(PLCB2) 118011244(PLCB4) 118011247(PLCB1) 118015997(PLCB3)
NSU: 110575943(PLCB3) 110579316(PLCB1) 110579349(PLCB4) 110585213(PLCB2)
LWW: 102736489 102739019(PLCB2) 102750198(PLCB3) 102751213(PLCB4)
FCA: 101090005(PLCB4) 101090942(PLCB2) 101092262(PLCB1) 101092961(PLCB3)
PYU: 121012476(PLCB1) 121012479(PLCB4) 121023937(PLCB3) 121041495(PLCB2)
PCOO: 112851908(PLCB3) 112855622(PLCB2) 112869362(PLCB4) 112869587(PLCB1)
PBG: 122468783(PLCB2) 122483945(PLCB3) 122496559(PLCB1) 122496563(PLCB4)
PVIV: 125162218(PLCB4) 125162435(PLCB1) 125167322(PLCB2) 125177240(PLCB3)
PTG: 102959485(PLCB2) 102960646(PLCB4) 102961121(PLCB1) 102961437(PLCB3)
PPAD: 109246661(PLCB3) 109263166(PLCB2) 109274721(PLCB4) 109274722(PLCB1)
HHV: 120226357(PLCB1) 120226638(PLCB4) 120232253(PLCB2) 120240178(PLCB3)
BTA: 281985(PLCB4) 287026(PLCB1) 508888(PLCB2) 515669(PLCB3)
BOM: 102264989(PLCB4) 102273347(PLCB1) 102276260(PLCB3) 102278948(PLCB2)
BIU: 109554384(PLCB3) 109564927(PLCB2) 109567852(PLCB1) 109567854(PLCB4)
BBUB: 102389945(PLCB2) 102405830(PLCB1) 102412320(PLCB4) 102413748(PLCB3)
BBIS: 104984484(PLCB4) 104984486(PLCB1) 104987189(PLCB3) 104994462(PLCB2)
CHX: 102169966(PLCB2) 102180505(PLCB4) 102188148(PLCB1) 102189653(PLCB3)
OAS: 101103585(PLCB1) 101106864(PLCB4) 101113074(PLCB2) 101116105(PLCB3)
BTAX: 128054050(PLCB2) 128058011(PLCB1) 128058303(PLCB4) 128068545(PLCB3)
ODA: 120853216(PLCB2) 120869193(PLCB4) 120869195(PLCB1) 120874626(PLCB3)
CCAD: 122430651(PLCB3) 122443383(PLCB2) 122448380(PLCB1) 122448381(PLCB4)
MBEZ: 129548814(PLCB3) 129556526(PLCB4) 129556560(PLCB1) 129563187(PLCB2)
SSC: 100152679(PLCB1) 100157641(PLCB2) 100516581(PLCB4) 100525148(PLCB3)
CFR: 102505338(PLCB3) 102509058(PLCB2) 102513431(PLCB4) 102513996(PLCB1)
CBAI: 105070632(PLCB3) 105077045(PLCB2) 105082996(PLCB4) 105082997(PLCB1)
CDK: 105096910(PLCB2) 105101292(PLCB1) 105101500(PLCB4) 105101545(PLCB3)
VPC: 102529315(PLCB1) 102529761(PLCB4) 102531845(PLCB2) 102538560(PLCB3)
BACU: 102997432(PLCB4) 103006361(PLCB3) 103007077(PLCB2) 103020805(PLCB1)
BMUS: 118881432(PLCB4) 118881571(PLCB1) 118889857(PLCB2) 118899866(PLCB3)
LVE: 103078639(PLCB4) 103079287(PLCB1) 103083884(PLCB3) 103086280(PLCB2)
OOR: 101270548(PLCB1) 101270961(PLCB4) 101274558(PLCB3) 101281417(PLCB2)
DLE: 111165617(PLCB4) 111165653(PLCB1) 111181753(PLCB2) 111183812(PLCB3)
PCAD: 102974165(PLCB3) 102983015(PLCB1) 102985636(PLCB2) 102995357(PLCB4)
PSIU: 116740640(PLCB1) 116740954(PLCB4) 116749106(PLCB2) 116758215(PLCB3)
NASI: 112391181(PLCB2) 112402291(PLCB3) 112412530(PLCB1) 112412538(PLCB4)
ECB: 100051485(PLCB4) 100051558(PLCB1) 100055407(PLCB3) 100057315(PLCB2)
EPZ: 103542193(PLCB3) 103559733(PLCB4) 103561633(PLCB2) 103562440(PLCB1)
EAI: 106823182(PLCB4) 106823191(PLCB1) 106833627(PLCB3) 106835172(PLCB2)
MYB: 102238655(PLCB3) 102240650(PLCB1) 102241255(PLCB4) 102254054(PLCB2)
MYD: 102751685(PLCB1) 102751959(PLCB4) 102755123(PLCB3) 102760520(PLCB2)
MMYO: 118649794(PLCB2) 118663015(PLCB1) 118663147(PLCB4) 118665361(PLCB3)
MLF: 102429686(PLCB1) 102432440(PLCB2) 102432706 102438291(PLCB3) 102441813(PLCB4)
MDT: 132239051(PLCB2) 132239361(PLCB4) 132239363(PLCB1) 132241471(PLCB3)
PKL: 118707269(PLCB3) 118707553(PLCB4) 118708478(PLCB1) 118723641(PLCB2)
EFUS: 103285666(PLCB1) 103285667(PLCB4) 103287505(PLCB2) 103302044(PLCB3)
MNA: 107536366(PLCB4) 107536369(PLCB1) 107539797(PLCB3) 107542967(PLCB2)
DRO: 112304122(PLCB4) 112304255(PLCB1) 112311437(PLCB2) 112317151(PLCB3)
SHON: 118990867(PLCB4) 118990869(PLCB1) 118991671(PLCB3) 118993594(PLCB2)
AJM: 119045446(PLCB3) 119057282(PLCB1) 119061296(PLCB2)
PDIC: 114492321(PLCB2) 114499423(PLCB3) 114506463(PLCB1) 114506992(PLCB4)
PHAS: 123808665(PLCB2) 123814755(PLCB1) 123814917(PLCB4) 123829335(PLCB3)
MMF: 118618293(PLCB1) 118618784(PLCB4) 118628278(PLCB3) 118632151(PLCB2)
PPAM: 129064066(PLCB2) 129068613(PLCB3) 129070855(PLCB4) 129070857(PLCB1)
HAI: 109378976(PLCB4) 109378977(PLCB1) 109383976(PLCB2) 109384329(PLCB3)
RFQ: 117015870(PLCB1) 117015942(PLCB4) 117024110(PLCB2) 117030619(PLCB3)
PALE: 102879238(PLCB3) 102885207(PLCB4) 102885781(PLCB1) 102885953(PLCB2)
PGIG: 120587190(PLCB2) 120600630(PLCB3) 120611916(PLCB4) 120611973(PLCB1)
PVP: 105288781(PLCB2) 105297846(PLCB3) 105298737(PLCB4) 105299444(PLCB1)
RAY: 107497081(PLCB3) 107506114(PLCB1) 107514464(PLCB2) 107519930(PLCB4)
MJV: 108394257(PLCB1) 108394259(PLCB4) 108401653(PLCB2) 108407569
TOD: 119232648(PLCB4) 119232657(PLCB1) 119238483(PLCB2) 119250024(PLCB3)
SARA: 101546811(PLCB4) 101547690(PLCB1) 101551223(PLCB2) 101559179(PLCB3)
SETR: 126017277(PLCB1) 126017588(PLCB3) 126018105(PLCB4) 126024570(PLCB2)
LAV: 100663829(PLCB3) 100668575(PLCB2) 100670617(PLCB4) 100672435(PLCB1)
ETF: 101647679(PLCB1) 101650582 101651304(PLCB3) 101656854(PLCB4)
DNM: 101413654(PLCB3) 101419878(PLCB4) 101420315(PLCB1) 101427179(PLCB2)
MDO: 100031263(PLCB3) 100031660(PLCB1) 100031869(PLCB2) 100033281(PLCB4)
GAS: 123233371(PLCB1) 123234085(PLCB2) 123236899(PLCB4) 123252777(PLCB3)
SHR: 100922938(PLCB3) 100929015(PLCB2) 100934049(PLCB4) 100934311(PLCB1)
PCW: 110195440(PLCB3) 110207938(PLCB1) 110207974(PLCB4) 110223673(PLCB2)
TVP: 118828622(PLCB2) 118841591(PLCB1) 118843823(PLCB4) 118853803(PLCB3)
OAA: 100078508(PLCB1) 100081349(PLCB3) 100084272(PLCB4) 100086536(PLCB2)
GGA: 416730(PLCB4) 423014(PLCB2) 427687(PLCB1)
PCOC: 116231881(PLCB1) 116231958(PLCB4) 116237964(PLCB2)
CJO: 107307599 107310934(PLCB4) 107310953(PLCB1) 107314230(PLCB2)
TPAI: 128075392(PLCB1) 128086570(PLCB2) 128087418(PLCB4)
LMUT: 125690171(PLCB4) 125690172(PLCB1) 125694452(PLCB2)
NMEL: 110395536(PLCB4) 110396662(PLCB1) 110401183(PLCB2)
APLA: 101790966(PLCB1) 101804447(PLCB2) 101805172(PLCB4)
ACYG: 106036606(PLCB4) 106036632(PLCB1) 106047056(PLCB2)
CATA: 118244676(PLCB2) 118251119(PLCB1) 118251121(PLCB4)
AFUL: 116487397(PLCB4) 116487565(PLCB1) 116490387(PLCB2)
TGU: 100219122(PLCB1) 100221959(PLCB4) 100229635(PLCB2)
LSR: 110475845(PLCB4) 110475847(PLCB1) 110484995(PLCB2)
SCAN: 103819233(PLCB4) 103819309(PLCB1) 103822183(PLCB2)
PMOA: 120500956(PLCB2) 120505243 120505902(PLCB1) 120505967(PLCB4)
OTC: 121335711(PLCB2) 121342624(PLCB1) 121342633(PLCB4)
PRUF: 121354771(PLCB2) 121357051(PLCB4) 121357055(PLCB1)
GFR: 102031336(PLCB4) 102037268(PLCB1) 102045029(PLCB2)
FAB: 101806047(PLCB2) 101812094(PLCB4) 101816169(PLCB1)
OMA: 130250780(PLCB1) 130251914(PLCB4) 130254499(PLCB2)
PHI: 102100609(PLCB4) 102105081(PLCB2) 102113003(PLCB1)
PMAJ: 107201330(PLCB1) 107201331(PLCB4) 107205812(PLCB2)
CCAE: 111926455(PLCB1) 111926460(PLCB4) 111930495(PLCB2)
CCW: 104691519(PLCB1) 104691520(PLCB4) 104692980(PLCB2)
CBRC: 103622983(PLCB4) 103623017(PLCB1) 103624416 103624745(PLCB2)
ETL: 114057366(PLCB4) 114065074(PLCB1) 114067935(PLCB2)
ZAB: 102062889(PLCB4) 102069763(PLCB1) 102071139(PLCB2)
ZLE: 135446187(PLCB1) 135446188(PLCB4) 135448882(PLCB2)
ACHL: 103801603(PLCB1) 103807029(PLCB4) 103809295(PLCB2)
SVG: 106854762(PLCB2) 106865172(PLCB4) 106865174(PLCB1)
MMEA: 130583339(PLCB2) 130583448(PLCB1) 130583454(PLCB4)
HRT: 120747796(PLCB3) 120751182 120753689(PLCB2)
SATI: 136359679(PLCB4) 136359680(PLCB1) 136362282(PLCB2)
FPG: 101912415(PLCB2) 101916711(PLCB4) 101922366(PLCB1)
FCH: 102048018(PLCB2) 102048448(PLCB1) 102054421(PLCB4)
CCRI: 104161116(PLCB4) 104165334(PLCB1) 104169665(PLCB2)
NNT: 104407434(PLCB4) 104407607(PLCB2) 104408755
SHAB: 115606933(PLCB2) 115609999(PLCB4) 115610001(PLCB1)
ACUN: 113477996(PLCB1) 113478160(PLCB4) 113481004(PLCB2)
TALA: 104358033(PLCB1) 104365698(PLCB2) 104365789(PLCB4)
ACHC: 115344237(PLCB4) 115344678(PLCB1) 115351830(PLCB2)
HALD: 104317497(PLCB1) 104317813(PLCB2) 104322394(PLCB4)
HLE: 104829833(PLCB2) 104835260 104836308(PLCB4) 104836447(PLCB1)
CSTI: 104552850 104557540(PLCB1)
LDI: 104343118(PLCB4) 104351797(PLCB2) 104352419(PLCB1)
MNB: 103771006(PLCB4) 103779156(PLCB2) 103781733(PLCB1)
DPUB: 104304410(PLCB2) 104305964(PLCB4) 104305988(PLCB1)
AVIT: 104273405(PLCB2) 104277566(PLCB1) 104280343(PLCB4)
BRHI: 104499999(PLCB4) 104500775(PLCB1) 104502280(PLCB2)
EGZ: 104131359(PLCB2) 104132995(PLCB4) 104133001(PLCB1)
NNI: 104020525(PLCB2) 104022433(PLCB4) 104022482(PLCB1)
PCRI: 104027940(PLCB4) 104028316(PLCB1) 104036936(PLCB2)
PCAO: 104042484(PLCB2) 104042697(PLCB4) 104045382(PLCB1)
PADL: 103913124(PLCB4) 103913125(PLCB1) 103924964(PLCB2)
AFOR: 103901613(PLCB1) 103901642(PLCB4) 103902618(PLCB2)
FGA: 104076458(PLCB1) 104082028(PLCB2) 104083314(PLCB4)
GSTE: 104255907(PLCB4) 104258535(PLCB1) 104260409(PLCB2)
CLV: 102096635(PLCB2) 102097554(PLCB4) 102098150(PLCB1)
MUI: 104545723(PLCB4)
PGUU: 104464519(PLCB4) 104471147(PLCB2)
PLET: 104617236(PLCB4) 104622838(PLCB1) 104628734(PLCB2)
EHS: 104507567(PLCB1) 104509459(PLCB2) 104510793(PLCB4)
CMAC: 104480585(PLCB4) 104485760(PLCB2) 104485890(PLCB1)
CUCA: 104055376(PLCB4) 104055439(PLCB1) 104064431(PLCB2)
TEO: 104373337 104376224(PLCB2) 104378121(PLCB4)
BREG: 104629864(PLCB4) 104636633(PLCB2) 104639332(PLCB1)
OHA: 104326710(PLCB2) 104330719(PLCB4) 104330725(PLCB1)
ACAR: 104522544(PLCB1) 104527135(PLCB4) 104528159(PLCB2)
CPEA: 104385132(PLCB2) 104397182(PLCB4) 104397210(PLCB1)
CVF: 104287337(PLCB4) 104287385(PLCB1) 104292993(PLCB2)
RTD: 128906836(PLCB4) 128907839(PLCB1) 128908469(PLCB2)
AAM: 106486714(PLCB2) 106490470(PLCB4) 106490480(PLCB1)
AROW: 112965294(PLCB1) 112965307(PLCB4) 112969665(PLCB2)
NPD: 112952062(PLCB2) 112958919(PLCB4) 112958952(PLCB1)
TGT: 104571101(PLCB4) 104576555(PLCB1) 104580063(PLCB2)
DNE: 112980039(PLCB4) 112980051(PLCB1) 112989515(PLCB2)
SCAM: 104141500(PLCB2) 104143465(PLCB1) 104143466(PLCB4)
ASN: 102371353(PLCB3) 102379390(PLCB4) 102381048(PLCB2) 102381939(PLCB1)
AMJ: 102560430(PLCB4) 102566880(PLCB1) 102572359(PLCB2) 102576994(PLCB3)
CPOO: 109319490(PLCB1) 109319491(PLCB4) 109321494(PLCB2)
GGN: 109296708(PLCB1) 109296711(PLCB4) 109298736(PLCB2)
PSS: 102449462(PLCB3) 102455767(PLCB4) 102460883(PLCB1) 102461092(PLCB2)
CMY: 102931046(PLCB2) 102932254(PLCB3) 102942020(PLCB1) 102942246(PLCB4)
CCAY: 125633375(PLCB4) 125633377(PLCB1) 125638409(PLCB2) 125640618(PLCB3)
DCC: 119853562(PLCB1) 119853782(PLCB4) 119857256(PLCB2) 119858763(PLCB3)
CPIC: 101930785(PLCB2) 101931546(PLCB4) 101932753(PLCB1) 101940400(PLCB3)
TST: 117874216(PLCB1) 117874218(PLCB4) 117876960(PLCB2) 117881048(PLCB3)
CABI: 116834011 116836497(PLCB4) 116837811(PLCB2) 116838816(PLCB3)
MRV: 120401080(PLCB4) 120401393(PLCB1) 120403585(PLCB2) 120408928(PLCB3)
ACS: 100551754(plcb2) 100560758(plcb4) 100566853(plcb1) 100567752(plcb3)
ASAO: 132764411 132765970(PLCB2) 132781449(PLCB1) 132781466(PLCB4)
PVT: 110080121(PLCB2) 110083359(PLCB3) 110087369 110087370(PLCB1)
SUND: 121915711(PLCB3) 121918973(PLCB4) 121918974(PLCB1) 121933158(PLCB2)
PBI: 103055449(PLCB2) 103057663(PLCB4) 103062216(PLCB1) 103064298(PLCB3) 103066383
PMUR: 107285365(PLCB1) 107285366(PLCB4) 107286221 107290817 107299064(PLCB3)
CTIG: 120307675(PLCB2) 120315294(PLCB4) 120315307(PLCB1) 120317177(PLCB3)
PGUT: 117665693(PLCB2) 117672323 117674364(PLCB1) 117674371(PLCB4) 132709243
APRI: 131186410(PLCB3) 131187650(PLCB2) 131197358(PLCB1) 131197364(PLCB4)
PTEX: 113442603(PLCB2) 113442692(PLCB4) 113442728(PLCB1) 113446578(PLCB3)
NSS: 113409982(PLCB2) 113412729(PLCB4) 113412730(PLCB1)
VKO: 123026780(PLCB2) 123032550(PLCB3) 123035714(PLCB4) 123035715(PLCB1)
PMUA: 114586167(PLCB3) 114593658(PLCB1) 114593659(PLCB4) 114593800(PLCB2)
PRAF: 128403455(PLCB3) 128410022(PLCB1) 128410023(PLCB4) 128410736(PLCB2)
ZVI: 118075670(PLCB3) 118082496(PLCB4) 118082497(PLCB1) 118083058(PLCB2)
HCG: 128337188(PLCB3) 128339357(PLCB2) 128340056(PLCB4) 128340057(PLCB1)
GJA: 107106753(PLCB1) 107115177(PLCB3) 107119642(PLCB2) 107123894(PLCB4)
STOW: 125427040(PLCB2) 125435056 125438128 125441600(PLCB3)
EMC: 129324816(PLCB2) 129326725(PLCB1) 129327269(PLCB4) 129338761(PLCB3)
XLA: 108699254(plcb2.L) 108716399(plcb4.L) 108716400 397692(plcb3.L) 445848(plcb4.S) 733258(plcb1.S)
XTR: 100125098(plcb4) 100487267(plcb3) 101734935(plcb2) 780394(plcb1)
NPR: 108789286(PLCB2) 108793965(PLCB3) 108795338(PLCB4) 108795563(PLCB1)
RTEM: 120917603(PLCB3) 120920645(PLCB2) 120938043(PLCB1) 120938046(PLCB4)
BBUF: 120980633(PLCB3) 120982179(PLCB2) 120998986(PLCB1) 120998995(PLCB4)
BGAR: 122920585(PLCB3) 122921617(PLCB2) 122933746(PLCB4) 122936263(PLCB1)
MUO: 115459092 115465668(PLCB1) 115465671(PLCB4) 115478003(PLCB2) 115479646(PLCB3)
GSH: 117357107(PLCB1) 117357108(PLCB4) 117364320(PLCB2) 117364437(PLCB3)
DRE: 100001532(plcb3) 100149080(plcb1l) 100537538(plcb4a) 407700(plcb4b) 569376(plcb2)
CERY: 137006304(plcb2) 137007131(plcb1) 137007133(plcb4a) 137019294(plcb4b) 137019295(plcb1l) 137031154(plcb3)
TRN: 134311634(plcb3) 134320705(plcb1l) 134320706 134325124(plcb2) 134325755 134325756(plcb4a)
LCO: 104919801(plcb4) 104920858(plcb1) 104924817(plcb2) 104928901(plcb3) 104935685
NCC: 104946378(plcb4) 104947200(plcb2) 104948204(plcb3) 104951799(plcb1)
CGOB: 115003421(plcb4) 115020236 115023588(plcb3) 115027304(plcb2) 115028862(plcb1)
EMAC: 134859199 134875837(plcb3) 134876796 134877086(plcb1l) 134881970(plcb2)
PLEP: 121953951(plcb2) 121955137 121955489 121961861(plcb3)
ESP: 116670665(plcb2) 116686556 116705016 116706249(plcb1) 116706250(plcb4)
ASTR: 137590308(plcb3) 137603511(plcb1) 137611209(plcb2) 137612994(plcb1l) 137612995
MZE: 101464832(plcb4) 101465812(plcb1) 101474135(plcb3) 101475994(plcb2) 101478971
ONL: 100689896 100698389(plcb1) 100706492(plcb3) 100706628(plcb4) 100706825(plcb2)
OLA: 100049465(plcb2) 100049529 100049535(plcb4) 101172698(plcb1) 101175365
CSAI: 133418720 133420813(plcb3) 133462872(plcb2) 133463587(plcb1) 133464380(plcb1l)
XMA: 102217878 102219479 102223820(plcb4) 102224078(plcb1) 102230660(plcb2)
XCO: 114133784(plcb2) 114138347 114157441 114158603(plcb1) 114158604(plcb4)
XHE: 116708418(plcb2) 116712647 116732702 116733614(plcb1) 116733615(plcb4)
PRET: 103457872(plcb1) 103457873(plcb4) 103458561(plcb2) 103476610 103480743(plcb3)
PFOR: 103133023(plcb4) 103136082(plcb2) 103148043(plcb1) 103150346 103154084
PLAI: 106946450(plcb1) 106947996 106952301(plcb2) 106954535(plcb4) 106959955
PMEI: 106904663 106913919(plcb2) 106926785(plcb1) 106927347(plcb4) 106929282
CVG: 107084147(plcb3) 107094391(plcb2) 107097625(plcb4) 107097779(plcb1) 107098647
NFU: 107376107 107377124(plcb3) 107378065(plcb4) 107378111(plcb1) 107392485(plcb2)
ALIM: 106518551(plcb4) 106518553(plcb1) 106519799(plcb2) 106524973(plcb3) 106529251
CSEM: 103381058(plcb1) 103381059(plcb4) 103385127(plcb3) 103387749 103389807(plcb2)
SDU: 111225989(plcb2) 111227394 111231312(plcb3) 111240392(plcb1) 111240424(plcb4)
SLAL: 111644585 111652449(plcb2) 111653469(plcb3) 111672675(plcb1) 111672676(plcb4)
SBIA: 133494594(plcb3) 133496879(plcb1l) 133496880 133509976(plcb1) 133513496(plcb2)
PTAO: 133468256(plcb1l) 133468257 133472875(plcb3) 133485980(plcb1) 133488201(plcb2)
MALB: 109961174 109962200(plcb4) 109962203(plcb1) 109965817(plcb3) 109968365(plcb2)
ELS: 105007096(plcb3) 105015712(plcb2) 105017520(plcb1) 105017521(plcb4) 105031658
SFM: 108919358(plcb2) 108922946 108925497(plcb3) 108929291 108929356(plcb4)
PKI: 111834703(plcb3) 111837852 111837866(plcb4) 111838879(plcb2) 111857883
LOC: 102682149(plcb4) 102682351(plcb1) 102691284(plcb2)
PSEX: 120516316 120516513 120518946(plcb2) 120539203(plcb3)
LCM: 102345855(PLCB1) 102348275(PLCB4) 102362364(PLCB2) 102365542(PLCB3)
AJC: 117101295
DME: Dmel_CG3620(norpA) Dmel_CG4574(Plc21C)
DSI: Dsimw501_GD16687(Dsim_GD16687) Dsimw501_GD23017(Dsim_GD23017)
DYA: Dyak_GE16341 Dyak_GE16747(Dyak_Plc21C)
DNV: 108658397
DCOR: 135792793(norpA)
BMOR: 100329153(PLCb1) 100329154(PLCb4)
PPOT: 106101440
HAW: 110382881(Norpa) 110384330
PXY: 105388539
DCI: 103508056
HHAL: 106680357(Plc21C) 106688812(norpA)
HVI: 124356652
MRJ: 136850580(norpA) 136854573
PPOI: 119091733
CEL: CELE_B0348.4(egl-8)
CBR: CBG_06373(Cbr-egl-8)
BMY: BM_BM1768(Bma-egl-8) BM_BM9957(Bm9957)
PVUL: 126821393
SHX: MS3_00006815(PLCB4_1)
EGL: EGR_00105
HMG: 100189549(plcbh1) 100189551(plcbh2) 100200484
HSY: 130640865
AQU: 100641378
 » show all
Reference
  Authors
Caricasole A, Sala C, Roncarati R, Formenti E, Terstappen GC
  Title
Cloning and characterization of the human phosphoinositide-specific phospholipase C-beta 1 (PLC beta 1).
  Journal
Biochim Biophys Acta 1517:63-72 (2000)
DOI:10.1016/S0167-4781(00)00260-8
  Sequence
[hsa:23236]
Reference
PMID:1644792
  Authors
Park D, Jhon DY, Kriz R, Knopf J, Rhee SG
  Title
Cloning, sequencing, expression, and Gq-independent activation of phospholipase C-beta 2.
  Journal
J Biol Chem 267:16048-55 (1992)
  Sequence
[hsa:5330]
Reference
PMID:1333955
  Authors
Carozzi AJ, Kriz RW, Webster C, Parker PJ
  Title
Identification, purification and characterization of a novel phosphatidylinositol-specific phospholipase C, a third member of the beta subfamily.
  Journal
Eur J Biochem 210:521-9 (1992)
DOI:10.1111/j.1432-1033.1992.tb17450.x
  Sequence
[hsa:5331]
Reference
PMID:8530101
  Authors
Alvarez RA, Ghalayini AJ, Xu P, Hardcastle A, Bhattacharya S, Rao PN, Pettenati MJ, Anderson RE, Baehr W
  Title
cDNA sequence and gene locus of the human retinal phosphoinositide-specific phospholipase-C beta 4 (PLCB4).
  Journal
Genomics 29:53-61 (1995)
DOI:10.1006/geno.1995.1214
  Sequence
[hsa:5332]

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