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 09100 Metabolism
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09120 Genetic Information Processing
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 09130 Environmental Information Processing
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09131 Membrane transport
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09132 Signal transduction
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 02020 Two-component system
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04010 MAPK signaling pathway [PATH:hsa04010]
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773 CACNA1A; calcium voltage-gated channel subunit alpha1 A
774 CACNA1B; calcium voltage-gated channel subunit alpha1 B
775 CACNA1C; calcium voltage-gated channel subunit alpha1 C
776 CACNA1D; calcium voltage-gated channel subunit alpha1 D
777 CACNA1E; calcium voltage-gated channel subunit alpha1 E
778 CACNA1F; calcium voltage-gated channel subunit alpha1 F
8913 CACNA1G; calcium voltage-gated channel subunit alpha1 G
8912 CACNA1H; calcium voltage-gated channel subunit alpha1 H
8911 CACNA1I; calcium voltage-gated channel subunit alpha1 I
779 CACNA1S; calcium voltage-gated channel subunit alpha1 S
781 CACNA2D1; calcium voltage-gated channel auxiliary subunit alpha2delta 1
9254 CACNA2D2; calcium voltage-gated channel auxiliary subunit alpha2delta 2
55799 CACNA2D3; calcium voltage-gated channel auxiliary subunit alpha2delta 3
93589 CACNA2D4; calcium voltage-gated channel auxiliary subunit alpha2delta 4
782 CACNB1; calcium voltage-gated channel auxiliary subunit beta 1
783 CACNB2; calcium voltage-gated channel auxiliary subunit beta 2
784 CACNB3; calcium voltage-gated channel auxiliary subunit beta 3
785 CACNB4; calcium voltage-gated channel auxiliary subunit beta 4
786 CACNG1; calcium voltage-gated channel auxiliary subunit gamma 1
10369 CACNG2; calcium voltage-gated channel auxiliary subunit gamma 2
10368 CACNG3; calcium voltage-gated channel auxiliary subunit gamma 3
27092 CACNG4; calcium voltage-gated channel auxiliary subunit gamma 4
27091 CACNG5; calcium voltage-gated channel auxiliary subunit gamma 5
59285 CACNG6; calcium voltage-gated channel auxiliary subunit gamma 6
59284 CACNG7; calcium voltage-gated channel auxiliary subunit gamma 7
59283 CACNG8; calcium voltage-gated channel auxiliary subunit gamma 8
5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
5578 PRKCA; protein kinase C alpha
5579 PRKCB; protein kinase C beta
5582 PRKCG; protein kinase C gamma
2768 GNA12; G protein subunit alpha 12
55970 GNG12; G protein subunit gamma 12
5530 PPP3CA; protein phosphatase 3 catalytic subunit alpha
5532 PPP3CB; protein phosphatase 3 catalytic subunit beta
5533 PPP3CC; protein phosphatase 3 catalytic subunit gamma
5534 PPP3R1; protein phosphatase 3 regulatory subunit B, alpha
5535 PPP3R2; protein phosphatase 3 regulatory subunit B, beta
5923 RASGRF1; Ras protein specific guanine nucleotide releasing factor 1
5924 RASGRF2; Ras protein specific guanine nucleotide releasing factor 2
10125 RASGRP1; RAS guanyl releasing protein 1
10235 RASGRP2; RAS guanyl releasing protein 2
25780 RASGRP3; RAS guanyl releasing protein 3
115727 RASGRP4; RAS guanyl releasing protein 4
9693 RAPGEF2; Rap guanine nucleotide exchange factor 2
4763 NF1; neurofibromin 1
5921 RASA1; RAS p21 protein activator 1
5922 RASA2; RAS p21 protein activator 2
5906 RAP1A; RAP1A, member of RAS oncogene family
5908 RAP1B; RAP1B, member of RAS oncogene family
1950 EGF; epidermal growth factor
7039 TGFA; transforming growth factor alpha
2069 EREG; epiregulin
374 AREG; amphiregulin
2246 FGF1; fibroblast growth factor 1
2247 FGF2; fibroblast growth factor 2
2248 FGF3; fibroblast growth factor 3
2249 FGF4; fibroblast growth factor 4
8822 FGF17; fibroblast growth factor 17
2251 FGF6; fibroblast growth factor 6
2252 FGF7; fibroblast growth factor 7
2253 FGF8; fibroblast growth factor 8
2254 FGF9; fibroblast growth factor 9
2255 FGF10; fibroblast growth factor 10
8823 FGF16; fibroblast growth factor 16
2250 FGF5; fibroblast growth factor 5
8817 FGF18; fibroblast growth factor 18
26281 FGF20; fibroblast growth factor 20
27006 FGF22; fibroblast growth factor 22
9965 FGF19; fibroblast growth factor 19
26291 FGF21; fibroblast growth factor 21
8074 FGF23; fibroblast growth factor 23
4803 NGF; nerve growth factor
627 BDNF; brain derived neurotrophic factor
4908 NTF3; neurotrophin 3
4909 NTF4; neurotrophin 4
3630 INS; insulin
3479 IGF1; insulin like growth factor 1
3481 IGF2; insulin like growth factor 2
5154 PDGFA; platelet derived growth factor subunit A
5155 PDGFB; platelet derived growth factor subunit B
56034 PDGFC; platelet derived growth factor C
80310 PDGFD; platelet derived growth factor D
1435 CSF1; colony stimulating factor 1
4254 KITLG; KIT ligand
2323 FLT3LG; fms related receptor tyrosine kinase 3 ligand
7422 VEGFA; vascular endothelial growth factor A
7423 VEGFB; vascular endothelial growth factor B
5228 PGF; placental growth factor
7424 VEGFC; vascular endothelial growth factor C
2277 VEGFD; vascular endothelial growth factor D
3082 HGF; hepatocyte growth factor
284 ANGPT1; angiopoietin 1
285 ANGPT2; angiopoietin 2
51378 ANGPT4; angiopoietin 4
1942 EFNA1; ephrin A1
1943 EFNA2; ephrin A2
1944 EFNA3; ephrin A3
1945 EFNA4; ephrin A4
1946 EFNA5; ephrin A5
2668 GDNF; glial cell derived neurotrophic factor
4902 NRTN; neurturin
9048 ARTN; artemin
5623 PSPN; persephin
1956 EGFR; epidermal growth factor receptor
2064 ERBB2; erb-b2 receptor tyrosine kinase 2
2065 ERBB3; erb-b2 receptor tyrosine kinase 3
2066 ERBB4; erb-b2 receptor tyrosine kinase 4
2260 FGFR1; fibroblast growth factor receptor 1
2263 FGFR2; fibroblast growth factor receptor 2
2261 FGFR3; fibroblast growth factor receptor 3
2264 FGFR4; fibroblast growth factor receptor 4
4804 NGFR; nerve growth factor receptor
4914 NTRK1; neurotrophic receptor tyrosine kinase 1
4915 NTRK2; neurotrophic receptor tyrosine kinase 2
3643 INSR; insulin receptor
3480 IGF1R; insulin like growth factor 1 receptor
5156 PDGFRA; platelet derived growth factor receptor alpha
5159 PDGFRB; platelet derived growth factor receptor beta
1436 CSF1R; colony stimulating factor 1 receptor
3815 KIT; KIT proto-oncogene, receptor tyrosine kinase
2322 FLT3; fms related receptor tyrosine kinase 3
2321 FLT1; fms related receptor tyrosine kinase 1
2324 FLT4; fms related receptor tyrosine kinase 4
3791 KDR; kinase insert domain receptor
4233 MET; MET proto-oncogene, receptor tyrosine kinase
7010 TEK; TEK receptor tyrosine kinase
1969 EPHA2; EPH receptor A2
5979 RET; ret proto-oncogene
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
6237 RRAS; RAS related
22800 RRAS2; RAS related 2
22808 MRAS; muscle RAS oncogene homolog
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
8649 LAMTOR3; late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
8569 MKNK1; MAPK interacting serine/threonine kinase 1
2872 MKNK2; MAPK interacting serine/threonine kinase 2
6197 RPS6KA3; ribosomal protein S6 kinase A3
6195 RPS6KA1; ribosomal protein S6 kinase A1
6196 RPS6KA2; ribosomal protein S6 kinase A2
27330 RPS6KA6; ribosomal protein S6 kinase A6
468 ATF4; activating transcription factor 4
2002 ELK1; ETS transcription factor ELK1
2005 ELK4; ETS transcription factor ELK4
4609 MYC; MYC proto-oncogene, bHLH transcription factor
6722 SRF; serum response factor
2353 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
4137 MAPT; microtubule associated protein tau
3925 STMN1; stathmin 1
123745 PLA2G4E; phospholipase A2 group IVE
5321 PLA2G4A; phospholipase A2 group IVA
8681 JMJD7-PLA2G4B; JMJD7-PLA2G4B readthrough
100137049 PLA2G4B; phospholipase A2 group IVB
8605 PLA2G4C; phospholipase A2 group IVC
283748 PLA2G4D; phospholipase A2 group IVD
255189 PLA2G4F; phospholipase A2 group IVF
7124 TNF; tumor necrosis factor
3552 IL1A; interleukin 1 alpha
3553 IL1B; interleukin 1 beta
7040 TGFB1; transforming growth factor beta 1
7042 TGFB2; transforming growth factor beta 2
7043 TGFB3; transforming growth factor beta 3
7132 TNFRSF1A; TNF receptor superfamily member 1A
3554 IL1R1; interleukin 1 receptor type 1
3556 IL1RAP; interleukin 1 receptor accessory protein
7046 TGFBR1; transforming growth factor beta receptor 1
7048 TGFBR2; transforming growth factor beta receptor 2
356 FASLG; Fas ligand
355 FAS; Fas cell surface death receptor
929 CD14; CD14 molecule
5879 RAC1; Rac family small GTPase 1
5880 RAC2; Rac family small GTPase 2
5881 RAC3; Rac family small GTPase 3
998 CDC42; cell division cycle 42
8717 TRADD; TNFRSF1A associated via death domain
836 CASP3; caspase 3
7186 TRAF2; TNF receptor associated factor 2
1616 DAXX; death domain associated protein
4615 MYD88; MYD88 innate immune signal transduction adaptor
3654 IRAK1; interleukin 1 receptor associated kinase 1
51135 IRAK4; interleukin 1 receptor associated kinase 4
7189 TRAF6; TNF receptor associated factor 6
1647 GADD45A; growth arrest and DNA damage inducible alpha
4616 GADD45B; growth arrest and DNA damage inducible beta
10912 GADD45G; growth arrest and DNA damage inducible gamma
10454 TAB1; TGF-beta activated kinase 1 (MAP3K7) binding protein 1
23118 TAB2; TGF-beta activated kinase 1 (MAP3K7) binding protein 2
51295 ECSIT; ECSIT signaling integrator
8491 MAP4K3; mitogen-activated protein kinase kinase kinase kinase 3
9448 MAP4K4; mitogen-activated protein kinase kinase kinase kinase 4
11184 MAP4K1; mitogen-activated protein kinase kinase kinase kinase 1
5058 PAK1; p21 (RAC1) activated kinase 1
5062 PAK2; p21 (RAC1) activated kinase 2
6789 STK4; serine/threonine kinase 4
6788 STK3; serine/threonine kinase 3
5871 MAP4K2; mitogen-activated protein kinase kinase kinase kinase 2
1326 MAP3K8; mitogen-activated protein kinase kinase kinase 8
4214 MAP3K1; mitogen-activated protein kinase kinase kinase 1
4296 MAP3K11; mitogen-activated protein kinase kinase kinase 11
10746 MAP3K2; mitogen-activated protein kinase kinase kinase 2
4215 MAP3K3; mitogen-activated protein kinase kinase kinase 3
4293 MAP3K9; mitogen-activated protein kinase kinase kinase 9
4294 MAP3K10; mitogen-activated protein kinase kinase kinase 10
84451 MAP3K21; mitogen-activated protein kinase kinase kinase 21
7786 MAP3K12; mitogen-activated protein kinase kinase kinase 12
9175 MAP3K13; mitogen-activated protein kinase kinase kinase 13
51776 MAP3K20; mitogen-activated protein kinase kinase kinase 20
9064 MAP3K6; mitogen-activated protein kinase kinase kinase 6
4217 MAP3K5; mitogen-activated protein kinase kinase kinase 5
6885 MAP3K7; mitogen-activated protein kinase kinase kinase 7
4216 MAP3K4; mitogen-activated protein kinase kinase kinase 4
9344 TAOK2; TAO kinase 2
51347 TAOK3; TAO kinase 3
57551 TAOK1; TAO kinase 1
6416 MAP2K4; mitogen-activated protein kinase kinase 4
5609 MAP2K7; mitogen-activated protein kinase kinase 7
5606 MAP2K3; mitogen-activated protein kinase kinase 3
5608 MAP2K6; mitogen-activated protein kinase kinase 6
9479 MAPK8IP1; mitogen-activated protein kinase 8 interacting protein 1
23542 MAPK8IP2; mitogen-activated protein kinase 8 interacting protein 2
23162 MAPK8IP3; mitogen-activated protein kinase 8 interacting protein 3
2316 FLNA; filamin A
1398 CRK; CRK proto-oncogene, adaptor protein
1399 CRKL; CRK like proto-oncogene, adaptor protein
408 ARRB1; arrestin beta 1
409 ARRB2; arrestin beta 2
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
5600 MAPK11; mitogen-activated protein kinase 11
6300 MAPK12; mitogen-activated protein kinase 12
5603 MAPK13; mitogen-activated protein kinase 13
1432 MAPK14; mitogen-activated protein kinase 14
8550 MAPKAPK5; MAPK activated protein kinase 5
9261 MAPKAPK2; MAPK activated protein kinase 2
7867 MAPKAPK3; MAPK activated protein kinase 3
9252 RPS6KA5; ribosomal protein S6 kinase A5
8986 RPS6KA4; ribosomal protein S6 kinase A4
994 CDC25B; cell division cycle 25B
4772 NFATC1; nuclear factor of activated T cells 1
4775 NFATC3; nuclear factor of activated T cells 3
3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
3727 JUND; JunD proto-oncogene, AP-1 transcription factor subunit
1386 ATF2; activating transcription factor 2
7157 TP53; tumor protein p53
1649 DDIT3; DNA damage inducible transcript 3
4149 MAX; MYC associated factor X
4208 MEF2C; myocyte enhancer factor 2C
3315 HSPB1; heat shock protein family B (small) member 1
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
5494 PPM1A; protein phosphatase, Mg2+/Mn2+ dependent 1A
5801 PTPRR; protein tyrosine phosphatase receptor type R
84867 PTPN5; protein tyrosine phosphatase non-receptor type 5
5778 PTPN7; protein tyrosine phosphatase non-receptor type 7
1843 DUSP1; dual specificity phosphatase 1
1846 DUSP4; dual specificity phosphatase 4
1844 DUSP2; dual specificity phosphatase 2
1849 DUSP7; dual specificity phosphatase 7
1850 DUSP8; dual specificity phosphatase 8
1847 DUSP5; dual specificity phosphatase 5
80824 DUSP16; dual specificity phosphatase 16
1848 DUSP6; dual specificity phosphatase 6
1852 DUSP9; dual specificity phosphatase 9
11221 DUSP10; dual specificity phosphatase 10
1845 DUSP3; dual specificity phosphatase 3
5536 PPP5C; protein phosphatase 5 catalytic subunit
5495 PPM1B; protein phosphatase, Mg2+/Mn2+ dependent 1B
3312 HSPA8; heat shock protein family A (Hsp70) member 8
3303 HSPA1A; heat shock protein family A (Hsp70) member 1A
3305 HSPA1L; heat shock protein family A (Hsp70) member 1 like
3304 HSPA1B; heat shock protein family A (Hsp70) member 1B
3310 HSPA6; heat shock protein family A (Hsp70) member 6
2122 MECOM; MDS1 and EVI1 complex locus
5607 MAP2K5; mitogen-activated protein kinase kinase 5
5598 MAPK7; mitogen-activated protein kinase 7
3164 NR4A1; nuclear receptor subfamily 4 group A member 1
9020 MAP3K14; mitogen-activated protein kinase kinase kinase 14
1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
51701 NLK; nemo like kinase
4790 NFKB1; nuclear factor kappa B subunit 1
4791 NFKB2; nuclear factor kappa B subunit 2
5970 RELA; RELA proto-oncogene, NF-kB subunit
5971 RELB; RELB proto-oncogene, NF-kB subunit
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K04344 CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
K04849 CACNA1B; voltage-dependent calcium channel N type alpha-1B
K04850 CACNA1C; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K04852 CACNA1E; voltage-dependent calcium channel R type alpha-1E
K04853 CACNA1F; voltage-dependent calcium channel L type alpha-1F
K04854 CACNA1G; voltage-dependent calcium channel T type alpha-1G
K04855 CACNA1H; voltage-dependent calcium channel T type alpha-1H
K04856 CACNA1I; voltage-dependent calcium channel T type alpha-1I
K04857 CACNA1S; voltage-dependent calcium channel L type alpha-1S
K04858 CACNA2D1; voltage-dependent calcium channel alpha-2/delta-1
K04859 CACNA2D2; voltage-dependent calcium channel alpha-2/delta-2
K04860 CACNA2D3; voltage-dependent calcium channel alpha-2/delta-3
K04861 CACNA2D4; voltage-dependent calcium channel alpha-2/delta-4
K04862 CACNB1; voltage-dependent calcium channel beta-1
K04863 CACNB2; voltage-dependent calcium channel beta-2
K04864 CACNB3; voltage-dependent calcium channel beta-3
K04865 CACNB4; voltage-dependent calcium channel beta-4
K04866 CACNG1; voltage-dependent calcium channel gamma-1
K04867 CACNG2; voltage-dependent calcium channel gamma-2
K04868 CACNG3; voltage-dependent calcium channel gamma-3
K04869 CACNG4; voltage-dependent calcium channel gamma-4
K04870 CACNG5; voltage-dependent calcium channel gamma-5
K04871 CACNG6; voltage-dependent calcium channel gamma-6
K04872 CACNG7; voltage-dependent calcium channel gamma-7
K04873 CACNG8; voltage-dependent calcium channel gamma-8
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K04349 RASGRF1; Ras-specific guanine nucleotide-releasing factor 1
K12326 RASGRF2; Ras-specific guanine nucleotide-releasing factor 2
K04350 RASGRP1; RAS guanyl-releasing protein 1
K12361 RASGRP2; RAS guanyl-releasing protein 2
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12363 RASGRP4; RAS guanyl-releasing protein 4
K08018 RAPGEF2; Rap guanine nucleotide exchange factor 2
K08052 NF1; neurofibromin 1
K04352 RASA1; Ras GTPase-activating protein 1
K08053 RASA2; Ras GTPase-activating protein 2
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K09784 EREG; epiregulin
K09782 AREG; amphiregulin
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K02582 NGFB; nerve growth factor, beta
K04355 BDNF; brain-derived neurotrophic factor
K04356 NTF3; neurotrophin 3
K12457 NTF4; neurotrophin 4
K04526 INS; insulin
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05450 PDGFC_D; platelet derived growth factor C/D
K05453 CSF1; macrophage colony-stimulating factor 1
K05461 KITLG; KIT ligand
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05460 HGF; hepatocyte growth factor
K05465 ANGPT1; angiopoietin 1
K05466 ANGPT2; angiopoietin 2
K05467 ANGPT4; angiopoietin 4
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05452 GDNF; glial cell derived neurotrophic factor
K25414 NRTN; neurturin
K25415 ARTN; artemin
K25416 PSPN; persephin
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05084 ERBB3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K05085 ERBB4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K02583 NGFR; tumor necrosis factor receptor superfamily member 16
K03176 NTRK1; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K04360 NTRK2; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
K04527 INSR; insulin receptor [EC:2.7.10.1]
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05090 CSF1R; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K05091 KIT; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05092 FLT3; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05096 FLT1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05097 FLT4; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K05098 KDR; kinase insert domain protein receptor [EC:2.7.10.1]
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05121 TEK; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
K05103 EPHA2; Eph receptor A2 [EC:2.7.10.1]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2; Ras-related protein R-Ras2
K07831 MRAS; Ras-related protein M-Ras
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04370 LAMTOR3; ragulator complex protein LAMTOR3
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04372 MKNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
K04372 MKNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
K04375 ELK1; ETS domain-containing protein Elk-1
K04376 ELK4; ETS domain-containing protein Elk-4
K04377 MYC; Myc proto-oncogene protein
K04378 SRF; serum response factor
K04379 FOS; proto-oncogene protein c-fos
K04380 MAPT; microtubule-associated protein tau
K04381 STMN1; stathmin 1
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K03156 TNF; tumor necrosis factor superfamily, member 2
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K03158 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A
K04386 IL1R1; interleukin 1 receptor type I
K04723 IL1RAP; interleukin 1 receptor accessory protein
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K04391 CD14; monocyte differentiation antigen CD14
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04393 CDC42; cell division control protein 42
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K02308 DAXX; death-associated protein 6
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04403 MAP3K7IP1; TAK1-binding protein 1
K04404 MAP3K7IP2; TAK1-binding protein 2
K04405 ECSIT; evolutionarily conserved signaling intermediate in Toll pathway
K04406 MAP4K3; mitogen-activated protein kinase kinase kinase kinase 3 [EC:2.7.11.1]
K04407 MAP4K4; mitogen-activated protein kinase kinase kinase kinase 4 [EC:2.7.11.1]
K04408 MAP4K1; mitogen-activated protein kinase kinase kinase kinase 1 [EC:2.7.11.1]
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K04411 STK4; serine/threonine kinase 4
K04412 STK3; serine/threonine kinase 3
K04414 MAP4K2; mitogen-activated protein kinase kinase kinase kinase 2 [EC:2.7.11.1]
K04415 MAP3K8; mitogen-activated protein kinase kinase kinase 8 [EC:2.7.11.25]
K04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K04419 MAP3K11; mitogen-activated protein kinase kinase kinase 11 [EC:2.7.11.25]
K04420 MAP3K2; mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25]
K04421 MAP3K3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
K04417 MAP3K9; mitogen-activated protein kinase kinase kinase 9 [EC:2.7.11.25]
K04418 MAP3K10; mitogen-activated protein kinase kinase kinase 10 [EC:2.7.11.25]
K17534 MLK4; mitogen-activated protein kinase kinase kinase MLK4 [EC:2.7.11.25]
K04423 MAP3K12; mitogen-activated protein kinase kinase kinase 12 [EC:2.7.11.25]
K04422 MAP3K13; mitogen-activated protein kinase kinase kinase 13 [EC:2.7.11.25]
K04424 ZAK; sterile alpha motif and leucine zipper containing kinase AZK [EC:2.7.11.25]
K04425 MAP3K6; mitogen-activated protein kinase kinase kinase 6 [EC:2.7.11.25]
K04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04428 MAP3K4; mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25]
K04429 TAO; thousand and one amino acid protein kinase [EC:2.7.11.1]
K04429 TAO; thousand and one amino acid protein kinase [EC:2.7.11.1]
K04429 TAO; thousand and one amino acid protein kinase [EC:2.7.11.1]
K04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04432 MAP2K3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04434 MAPK8IP1; mitogen-activated protein kinase 8 interacting protein 1
K04435 MAPK8IP2; mitogen-activated protein kinase 8 interacting protein 2
K04436 MAPK8IP3; mitogen-activated protein kinase 8 interacting protein 3
K04437 FLNA; filamin-A
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K04439 ARRB; beta-arrestin
K04439 ARRB; beta-arrestin
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04442 MAPKAPK5; mitogen-activated protein kinase-activated protein kinase 5 [EC:2.7.11.1]
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K04444 MAPKAPK3; mitogen-activated protein kinase-activated protein kinase 3 [EC:2.7.11.1]
K04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K16510 RPS6KA4; ribosomal protein S6 kinase alpha-4 [EC:2.7.11.1]
K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
K04446 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
K17333 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3
K04448 JUN; transcription factor AP-1
K04449 JUND; transcription factor jun-D
K04450 ATF2; cyclic AMP-dependent transcription factor ATF-2
K04451 TP53; tumor protein p53
K04452 DDIT3; DNA damage-inducible transcript 3
K04453 MAX; Max protein
K04454 MEF2C; MADS-box transcription enhancer factor 2C
K04455 HSPB1; heat shock protein beta-1
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04457 PPM1A; protein phosphatase 1A [EC:3.1.3.16]
K04458 PTPRR; receptor-type tyrosine-protein phosphatase R [EC:3.1.3.48]
K18018 PTPN5; tyrosine-protein phosphatase non-receptor type 5 [EC:3.1.3.48]
K18019 PTPN7; tyrosine-protein phosphatase non-receptor type 7 [EC:3.1.3.48]
K21278 DUSP1; dual specificity protein phosphatase 1 [EC:3.1.3.16 3.1.3.48]
K04459 DUSP; dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
K04459 DUSP; dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
K04459 DUSP; dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
K04459 DUSP; dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
K04459 DUSP; dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
K04459 DUSP; dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
K21946 DUSP6; dual specificity phosphatase 6 [EC:3.1.3.16 3.1.3.48]
K18498 DUSP9; dual specificity phosphatase 9 [EC:3.1.3.16 3.1.3.48]
K20216 DUSP10; dual specificity phosphatase 10 [EC:3.1.3.16 3.1.3.48]
K17614 DUSP3; dual specificity phosphatase 3 [EC:3.1.3.16 3.1.3.48]
K04460 PPP5C; serine/threonine-protein phosphatase 5 [EC:3.1.3.16]
K04461 PPM1B; protein phosphatase 1B [EC:3.1.3.16]
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K04462 MECOM; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
K04463 MAP2K5; mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K04465 NR4A1; nuclear receptor subfamily 4 group A member 1
K04466 MAP3K14; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04468 NLK; nemo like kinase [EC:2.7.11.24]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K04735 RELA; transcription factor p65
K09253 RELB; transcription factor RelB
|
04013 MAPK signaling pathway - fly
|
04016 MAPK signaling pathway - plant
|
04011 MAPK signaling pathway - yeast
|
04012 ErbB signaling pathway [PATH:hsa04012]
|
1950 EGF; epidermal growth factor
7039 TGFA; transforming growth factor alpha
374 AREG; amphiregulin
1956 EGFR; epidermal growth factor receptor
2064 ERBB2; erb-b2 receptor tyrosine kinase 2
5335 PLCG1; phospholipase C gamma 1
5336 PLCG2; phospholipase C gamma 2
815 CAMK2A; calcium/calmodulin dependent protein kinase II alpha
817 CAMK2D; calcium/calmodulin dependent protein kinase II delta
816 CAMK2B; calcium/calmodulin dependent protein kinase II beta
818 CAMK2G; calcium/calmodulin dependent protein kinase II gamma
5578 PRKCA; protein kinase C alpha
5579 PRKCB; protein kinase C beta
5582 PRKCG; protein kinase C gamma
867 CBL; Cbl proto-oncogene
868 CBLB; Cbl proto-oncogene B
6776 STAT5A; signal transducer and activator of transcription 5A
6777 STAT5B; signal transducer and activator of transcription 5B
6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase
5747 PTK2; protein tyrosine kinase 2
1398 CRK; CRK proto-oncogene, adaptor protein
1399 CRKL; CRK like proto-oncogene, adaptor protein
25 ABL1; ABL proto-oncogene 1, non-receptor tyrosine kinase
27 ABL2; ABL proto-oncogene 2, non-receptor tyrosine kinase
4690 NCK1; NCK adaptor protein 1
8440 NCK2; NCK adaptor protein 2
5058 PAK1; p21 (RAC1) activated kinase 1
5062 PAK2; p21 (RAC1) activated kinase 2
5063 PAK3; p21 (RAC1) activated kinase 3
10298 PAK4; p21 (RAC1) activated kinase 4
57144 PAK5; p21 (RAC1) activated kinase 5
56924 PAK6; p21 (RAC1) activated kinase 6
106821730 BUB1B-PAK6; BUB1B-PAK6 readthrough
6416 MAP2K4; mitogen-activated protein kinase kinase 4
5609 MAP2K7; mitogen-activated protein kinase kinase 7
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
2002 ELK1; ETS transcription factor ELK1
685 BTC; betacellulin
1839 HBEGF; heparin binding EGF like growth factor
2069 EREG; epiregulin
2065 ERBB3; erb-b2 receptor tyrosine kinase 3
3084 NRG1; neuregulin 1
9542 NRG2; neuregulin 2
2066 ERBB4; erb-b2 receptor tyrosine kinase 4
6464 SHC1; SHC adaptor protein 1
25759 SHC2; SHC adaptor protein 2
53358 SHC3; SHC adaptor protein 3
399694 SHC4; SHC adaptor protein 4
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
4609 MYC; MYC proto-oncogene, bHLH transcription factor
2549 GAB1; GRB2 associated binding protein 1
10718 NRG3; neuregulin 3
145957 NRG4; neuregulin 4
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
2475 MTOR; mechanistic target of rapamycin kinase
6198 RPS6KB1; ribosomal protein S6 kinase B1
6199 RPS6KB2; ribosomal protein S6 kinase B2
1978 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
572 BAD; BCL2 associated agonist of cell death
2932 GSK3B; glycogen synthase kinase 3 beta
1027 CDKN1B; cyclin dependent kinase inhibitor 1B
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
|
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K09782 AREG; amphiregulin
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K08887 ABL2; abelson tyrosine-protein kinase 2 [EC:2.7.10.2]
K07365 NCK1; NCK adaptor protein 1
K19862 NCK2; NCK adaptor protein 2
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04375 ELK1; ETS domain-containing protein Elk-1
K09783 BTC; betacellulin
K08523 HBEGF; heparin-binding EGF-like growth factor
K09784 EREG; epiregulin
K05084 ERBB3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K05455 NRG1; neuregulin 1
K05456 NRG2; neuregulin 2
K05085 ERBB4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04377 MYC; Myc proto-oncogene protein
K09593 GAB1; GRB2-associated-binding protein 1
K05457 NRG3; neuregulin 3
K05458 NRG4; neuregulin 4
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K02158 BAD; Bcl-2-antagonist of cell death
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
|
04014 Ras signaling pathway [PATH:hsa04014]
|
04015 Rap1 signaling pathway [PATH:hsa04015]
|
5906 RAP1A; RAP1A, member of RAS oncogene family
5908 RAP1B; RAP1B, member of RAS oncogene family
22808 MRAS; muscle RAS oncogene homolog
9771 RAPGEF5; Rap guanine nucleotide exchange factor 5
9732 DOCK4; dedicator of cytokinesis 4
2902 GRIN1; glutamate ionotropic receptor NMDA type subunit 1
2903 GRIN2A; glutamate ionotropic receptor NMDA type subunit 2A
2904 GRIN2B; glutamate ionotropic receptor NMDA type subunit 2B
810 CALML3; calmodulin like 3
805 CALM2; calmodulin 2
808 CALM3; calmodulin 3
801 CALM1; calmodulin 1
163688 CALML6; calmodulin like 6
51806 CALML5; calmodulin like 5
91860 CALML4; calmodulin like 4
2149 F2R; coagulation factor II thrombin receptor
9002 F2RL3; F2R like thrombin or trypsin receptor 3
5028 P2RY1; purinergic receptor P2Y1
2357 FPR1; formyl peptide receptor 1
1902 LPAR1; lysophosphatidic acid receptor 1
9170 LPAR2; lysophosphatidic acid receptor 2
23566 LPAR3; lysophosphatidic acid receptor 3
2846 LPAR4; lysophosphatidic acid receptor 4
57121 LPAR5; lysophosphatidic acid receptor 5
135 ADORA2A; adenosine A2a receptor
136 ADORA2B; adenosine A2b receptor
2778 GNAS; GNAS complex locus
107 ADCY1; adenylate cyclase 1
108 ADCY2; adenylate cyclase 2
109 ADCY3; adenylate cyclase 3
196883 ADCY4; adenylate cyclase 4
111 ADCY5; adenylate cyclase 5
112 ADCY6; adenylate cyclase 6
113 ADCY7; adenylate cyclase 7
114 ADCY8; adenylate cyclase 8
115 ADCY9; adenylate cyclase 9
10411 RAPGEF3; Rap guanine nucleotide exchange factor 3
11069 RAPGEF4; Rap guanine nucleotide exchange factor 4
2776 GNAQ; G protein subunit alpha q
23236 PLCB1; phospholipase C beta 1
5330 PLCB2; phospholipase C beta 2
5331 PLCB3; phospholipase C beta 3
5332 PLCB4; phospholipase C beta 4
25780 RASGRP3; RAS guanyl releasing protein 3
10235 RASGRP2; RAS guanyl releasing protein 2
1950 EGF; epidermal growth factor
2246 FGF1; fibroblast growth factor 1
2247 FGF2; fibroblast growth factor 2
2248 FGF3; fibroblast growth factor 3
2249 FGF4; fibroblast growth factor 4
8822 FGF17; fibroblast growth factor 17
2251 FGF6; fibroblast growth factor 6
2252 FGF7; fibroblast growth factor 7
2253 FGF8; fibroblast growth factor 8
2254 FGF9; fibroblast growth factor 9
2255 FGF10; fibroblast growth factor 10
8823 FGF16; fibroblast growth factor 16
2250 FGF5; fibroblast growth factor 5
8817 FGF18; fibroblast growth factor 18
26281 FGF20; fibroblast growth factor 20
27006 FGF22; fibroblast growth factor 22
9965 FGF19; fibroblast growth factor 19
26291 FGF21; fibroblast growth factor 21
8074 FGF23; fibroblast growth factor 23
4803 NGF; nerve growth factor
3630 INS; insulin
3479 IGF1; insulin like growth factor 1
5154 PDGFA; platelet derived growth factor subunit A
5155 PDGFB; platelet derived growth factor subunit B
56034 PDGFC; platelet derived growth factor C
80310 PDGFD; platelet derived growth factor D
1435 CSF1; colony stimulating factor 1
4254 KITLG; KIT ligand
7422 VEGFA; vascular endothelial growth factor A
7423 VEGFB; vascular endothelial growth factor B
5228 PGF; placental growth factor
7424 VEGFC; vascular endothelial growth factor C
2277 VEGFD; vascular endothelial growth factor D
3082 HGF; hepatocyte growth factor
284 ANGPT1; angiopoietin 1
285 ANGPT2; angiopoietin 2
51378 ANGPT4; angiopoietin 4
1942 EFNA1; ephrin A1
1943 EFNA2; ephrin A2
1944 EFNA3; ephrin A3
1945 EFNA4; ephrin A4
1946 EFNA5; ephrin A5
1956 EGFR; epidermal growth factor receptor
2260 FGFR1; fibroblast growth factor receptor 1
2263 FGFR2; fibroblast growth factor receptor 2
2261 FGFR3; fibroblast growth factor receptor 3
2264 FGFR4; fibroblast growth factor receptor 4
4804 NGFR; nerve growth factor receptor
3643 INSR; insulin receptor
3480 IGF1R; insulin like growth factor 1 receptor
5156 PDGFRA; platelet derived growth factor receptor alpha
5159 PDGFRB; platelet derived growth factor receptor beta
1436 CSF1R; colony stimulating factor 1 receptor
3815 KIT; KIT proto-oncogene, receptor tyrosine kinase
2321 FLT1; fms related receptor tyrosine kinase 1
2324 FLT4; fms related receptor tyrosine kinase 4
3791 KDR; kinase insert domain receptor
4233 MET; MET proto-oncogene, receptor tyrosine kinase
7010 TEK; TEK receptor tyrosine kinase
1969 EPHA2; EPH receptor A2
1398 CRK; CRK proto-oncogene, adaptor protein
1399 CRKL; CRK like proto-oncogene, adaptor protein
2889 RAPGEF1; Rap guanine nucleotide exchange factor 1
9564 BCAR1; BCAR1 scaffold protein, Cas family member
999 CDH1; cadherin 1
1499 CTNNB1; catenin beta 1
9223 MAGI1; membrane associated guanylate kinase, WW and PDZ domain containing 1
9863 MAGI2; membrane associated guanylate kinase, WW and PDZ domain containing 2
260425 MAGI3; membrane associated guanylate kinase, WW and PDZ domain containing 3
9693 RAPGEF2; Rap guanine nucleotide exchange factor 2
51735 RAPGEF6; Rap guanine nucleotide exchange factor 6
27040 LAT; linker for activation of T cells
2533 FYB1; FYN binding protein 1
3937 LCP2; lymphocyte cytosolic protein 2
8631 SKAP1; src kinase associated phosphoprotein 1
5335 PLCG1; phospholipase C gamma 1
5578 PRKCA; protein kinase C alpha
5579 PRKCB; protein kinase C beta
5582 PRKCG; protein kinase C gamma
5587 PRKD1; protein kinase D1
23683 PRKD3; protein kinase D3
25865 PRKD2; protein kinase D2
1813 DRD2; dopamine receptor D2
1268 CNR1; cannabinoid receptor 1
2770 GNAI1; G protein subunit alpha i1
2773 GNAI3; G protein subunit alpha i3
2771 GNAI2; G protein subunit alpha i2
2775 GNAO1; G protein subunit alpha o1
5909 RAP1GAP; RAP1 GTPase activating protein
26037 SIPA1L1; signal induced proliferation associated 1 like 1
6494 SIPA1; signal-induced proliferation-associated 1
57568 SIPA1L2; signal induced proliferation associated 1 like 2
23094 SIPA1L3; signal induced proliferation associated 1 like 3
3397 ID1; inhibitor of DNA binding 1
7057 THBS1; thrombospondin 1
5900 RALGDS; ral guanine nucleotide dissociation stimulator
5898 RALA; RAS like proto-oncogene A
5899 RALB; RAS like proto-oncogene B
5879 RAC1; Rac family small GTPase 1
5880 RAC2; Rac family small GTPase 2
5881 RAC3; Rac family small GTPase 3
54518 APBB1IP; amyloid beta precursor protein binding family B member 1 interacting protein
7094 TLN1; talin 1
83660 TLN2; talin 2
3674 ITGA2B; integrin subunit alpha 2b
3690 ITGB3; integrin subunit beta 3
345456 PFN3; profilin 3
5216 PFN1; profilin 1
5217 PFN2; profilin 2
375189 PFN4; profilin family member 4
7408 VASP; vasodilator stimulated phosphoprotein
55740 ENAH; ENAH actin regulator
51466 EVL; Enah/Vasp-like
71 ACTG1; actin gamma 1
60 ACTB; actin beta
64411 ARAP3; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
387 RHOA; ras homolog family member A
6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase
9855 FARP2; FERM, ARH/RhoGEF and pleckstrin domain protein 2
998 CDC42; cell division cycle 42
10451 VAV3; vav guanine nucleotide exchange factor 3
7409 VAV1; vav guanine nucleotide exchange factor 1
7410 VAV2; vav guanine nucleotide exchange factor 2
7074 TIAM1; TIAM Rac1 associated GEF 1
56288 PARD3; par-3 family cell polarity regulator
50855 PARD6A; par-6 family cell polarity regulator alpha
84552 PARD6G; par-6 family cell polarity regulator gamma
84612 PARD6B; par-6 family cell polarity regulator beta
5590 PRKCZ; protein kinase C zeta
5584 PRKCI; protein kinase C iota
4301 AFDN; afadin, adherens junction formation factor
1500 CTNND1; catenin delta 1
889 KRIT1; KRIT1 ankyrin repeat containing
10636 RGS14; regulator of G protein signaling 14
83593 RASSF5; Ras association domain family member 5
3683 ITGAL; integrin subunit alpha L
3684 ITGAM; integrin subunit alpha M
3689 ITGB2; integrin subunit beta 2
3688 ITGB1; integrin subunit beta 1
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
5606 MAP2K3; mitogen-activated protein kinase kinase 3
5608 MAP2K6; mitogen-activated protein kinase kinase 6
5600 MAPK11; mitogen-activated protein kinase 11
6300 MAPK12; mitogen-activated protein kinase 12
5603 MAPK13; mitogen-activated protein kinase 13
1432 MAPK14; mitogen-activated protein kinase 14
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
51196 PLCE1; phospholipase C epsilon 1
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
6237 RRAS; RAS related
|
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K07831 MRAS; Ras-related protein M-Ras
K08019 RAPGEF5; Rap guanine nucleotide exchange factor 5
K17697 DOCK4; dedicator of cytokinesis protein 4
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K03914 F2R; coagulation factor II (thrombin) receptor
K04236 F2RL3; coagulation factor II (thrombin) receptor-like 3
K04270 P2RY1; P2Y purinoceptor 1
K04172 FPR1; formyl peptide receptor 1
K04289 LPAR1; lysophosphatidic acid receptor 1
K04291 LPAR2; lysophosphatidic acid receptor 2
K04294 LPAR3; lysophosphatidic acid receptor 3
K04275 LPAR4; lysophosphatidic acid receptor 4
K08390 LPAR5; lysophosphatidic acid receptor 5
K04266 ADORA2A; adenosine receptor A2a
K04267 ADORA2B; adenosine receptor A2b
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K08014 RAPGEF3; Rap guanine nucleotide exchange factor 3
K04351 RAPGEF4; Rap guanine nucleotide exchange factor 4
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12361 RASGRP2; RAS guanyl-releasing protein 2
K04357 EGF; epidermal growth factor
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K02582 NGFB; nerve growth factor, beta
K04526 INS; insulin
K05459 IGF1; insulin-like growth factor 1
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05450 PDGFC_D; platelet derived growth factor C/D
K05453 CSF1; macrophage colony-stimulating factor 1
K05461 KITLG; KIT ligand
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05460 HGF; hepatocyte growth factor
K05465 ANGPT1; angiopoietin 1
K05466 ANGPT2; angiopoietin 2
K05467 ANGPT4; angiopoietin 4
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K02583 NGFR; tumor necrosis factor receptor superfamily member 16
K04527 INSR; insulin receptor [EC:2.7.10.1]
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05090 CSF1R; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K05091 KIT; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05096 FLT1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05097 FLT4; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K05098 KDR; kinase insert domain protein receptor [EC:2.7.10.1]
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05121 TEK; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
K05103 EPHA2; Eph receptor A2 [EC:2.7.10.1]
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K06277 RAPGEF1; Rap guanine nucleotide exchange factor 1
K05726 BCAR1; breast cancer anti-estrogen resistance 1
K05689 CDH1; cadherin 1, type 1, E-cadherin
K02105 CTNNB1; catenin beta 1
K05631 AIP3; atrophin-1 interacting protein 3 (BAI1-associated protein 1)
K05629 AIP1; atrophin-1 interacting protein 1
K06112 MAGI3; membrane-associated guanylate kinase-related
K08018 RAPGEF2; Rap guanine nucleotide exchange factor 2
K08020 RAPGEF6; Rap guanine nucleotide exchange factor 6
K07362 LAT; linker for activation of T cells family member 1
K17698 FYB; FYN binding protein
K07361 LCP2; lymphocyte cytosolic protein 2
K17699 SKAP1; src kinase associated phosphoprotein 1
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K06070 PKD; protein kinase D [EC:2.7.11.13]
K06070 PKD; protein kinase D [EC:2.7.11.13]
K06070 PKD; protein kinase D [EC:2.7.11.13]
K04145 DRD2; dopamine receptor D2
K04277 CNR1; cannabinoid receptor 1
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO; guanine nucleotide-binding protein G(o) subunit alpha
K17700 RAP1GAP; RAP1 GTPase activating protein 1
K17701 SIPA1L1; signal-induced proliferation-associated 1 like protein 1
K08013 SIPA1; signal-induced proliferation-associated gene 1
K17702 SIPA1L2; signal-induced proliferation-associated 1 like protein 2
K17703 SIPA1L3; signal-induced proliferation-associated 1 like protein 3
K04680 ID1; DNA-binding protein inhibitor ID1
K16857 THBS1; thrombospondin 1
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K17704 APBB1IP; amyloid beta A4 precursor protein-binding family B member 1-interacting protein
K06271 TLN; talin
K06271 TLN; talin
K06476 ITGA2B; integrin alpha 2B
K06493 ITGB3; integrin beta 3
K05759 PFN; profilin
K05759 PFN; profilin
K05759 PFN; profilin
K05759 PFN; profilin
K06274 VASP; vasodilator-stimulated phosphoprotein
K05746 ENAH; enabled
K23487 EVL; Ena/VASP-like protein
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
K12490 ARAP3; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
K04513 RHOA; Ras homolog gene family, member A
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K06082 FARP2; FERM, RhoGEF and pleckstrin domain protein 2
K04393 CDC42; cell division control protein 42
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K05731 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
K04237 PARD3; partitioning defective protein 3
K06093 PARD6; partitioning defective protein 6
K06093 PARD6; partitioning defective protein 6
K06093 PARD6; partitioning defective protein 6
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K06069 PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]
K05702 AF6; afadin
K05690 CTNND1; catenin (cadherin-associated protein), delta 1
K17705 KRIT1; Krev interaction trapped protein 1
K17706 RGS14; regulator of G-protein signaling 14
K08015 RASSF5; Ras association domain-containing protein 5
K05718 ITGAL; integrin alpha L
K06461 ITGAM; integrin alpha M
K06464 ITGB2; integrin beta 2
K05719 ITGB1; integrin beta 1
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04432 MAP2K3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K05860 PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K07829 RRAS; Ras-related protein R-Ras
|
04310 Wnt signaling pathway [PATH:hsa04310]
|
04330 Notch signaling pathway [PATH:hsa04330]
|
04340 Hedgehog signaling pathway [PATH:hsa04340]
|
04341 Hedgehog signaling pathway - fly
|
04350 TGF-beta signaling pathway [PATH:hsa04350]
|
04390 Hippo signaling pathway [PATH:hsa04390]
|
04391 Hippo signaling pathway - fly
|
04392 Hippo signaling pathway - multiple species [PATH:hsa04392]
|
04370 VEGF signaling pathway [PATH:hsa04370]
|
04371 Apelin signaling pathway [PATH:hsa04371]
|
04630 JAK-STAT signaling pathway [PATH:hsa04630]
|
04064 NF-kappa B signaling pathway [PATH:hsa04064]
|
04668 TNF signaling pathway [PATH:hsa04668]
|
04066 HIF-1 signaling pathway [PATH:hsa04066]
|
04068 FoxO signaling pathway [PATH:hsa04068]
|
7040 TGFB1; transforming growth factor beta 1
7042 TGFB2; transforming growth factor beta 2
7043 TGFB3; transforming growth factor beta 3
7046 TGFBR1; transforming growth factor beta receptor 1
7048 TGFBR2; transforming growth factor beta receptor 2
4089 SMAD4; SMAD family member 4
4088 SMAD3; SMAD family member 3
6794 STK11; serine/threonine kinase 11
5562 PRKAA1; protein kinase AMP-activated catalytic subunit alpha 1
5563 PRKAA2; protein kinase AMP-activated catalytic subunit alpha 2
5564 PRKAB1; protein kinase AMP-activated non-catalytic subunit beta 1
5565 PRKAB2; protein kinase AMP-activated non-catalytic subunit beta 2
5571 PRKAG1; protein kinase AMP-activated non-catalytic subunit gamma 1
53632 PRKAG3; protein kinase AMP-activated non-catalytic subunit gamma 3
51422 PRKAG2; protein kinase AMP-activated non-catalytic subunit gamma 2
51701 NLK; nemo like kinase
6502 SKP2; S-phase kinase associated protein 2
4193 MDM2; MDM2 proto-oncogene
80854 SETD7; SET domain containing 7, histone lysine methyltransferase
1387 CREBBP; CREB binding protein
2033 EP300; E1A binding protein p300
23411 SIRT1; sirtuin 1
7874 USP7; ubiquitin specific peptidase 7
6517 SLC2A4; solute carrier family 2 member 4
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
6789 STK4; serine/threonine kinase 4
3479 IGF1; insulin like growth factor 1
3480 IGF1R; insulin like growth factor 1 receptor
3630 INS; insulin
3643 INSR; insulin receptor
3667 IRS1; insulin receptor substrate 1
8660 IRS2; insulin receptor substrate 2
8471 IRS4; insulin receptor substrate 4
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
5170 PDPK1; 3-phosphoinositide dependent protein kinase 1
1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
5728 PTEN; phosphatase and tensin homolog
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
6446 SGK1; serum/glucocorticoid regulated kinase 1
10110 SGK2; serum/glucocorticoid regulated kinase 2
23678 SGK3; serum/glucocorticoid regulated kinase family member 3
100533105 C8orf44-SGK3; C8orf44-SGK3 readthrough
2308 FOXO1; forkhead box O1
2309 FOXO3; forkhead box O3
4303 FOXO4; forkhead box O4
100132074 FOXO6; forkhead box O6
2911 GRM1; glutamate metabotropic receptor 1
9456 HOMER1; homer scaffold protein 1
9455 HOMER2; homer scaffold protein 2
9454 HOMER3; homer scaffold protein 3
116986 AGAP2; ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
1454 CSNK1E; casein kinase 1 epsilon
102800317 TPTEP2-CSNK1E; TPTEP2-CSNK1E readthrough
3569 IL6; interleukin 6
3586 IL10; interleukin 10
6774 STAT3; signal transducer and activator of transcription 3
1950 EGF; epidermal growth factor
1956 EGFR; epidermal growth factor receptor
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
5600 MAPK11; mitogen-activated protein kinase 11
6300 MAPK12; mitogen-activated protein kinase 12
5603 MAPK13; mitogen-activated protein kinase 13
1432 MAPK14; mitogen-activated protein kinase 14
1017 CDK2; cyclin dependent kinase 2
3276 PRMT1; protein arginine methyltransferase 1
2290 FOXG1; forkhead box G1
891 CCNB1; cyclin B1
9133 CCNB2; cyclin B2
85417 CCNB3; cyclin B3
595 CCND1; cyclin D1
894 CCND2; cyclin D2
901 CCNG2; cyclin G2
1030 CDKN2B; cyclin dependent kinase inhibitor 2B
1032 CDKN2D; cyclin dependent kinase inhibitor 2D
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
1027 CDKN1B; cyclin dependent kinase inhibitor 1B
5934 RBL2; RB transcriptional corepressor like 2
5347 PLK1; polo like kinase 1
10769 PLK2; polo like kinase 2
1263 PLK3; polo like kinase 3
10733 PLK4; polo like kinase 4
1647 GADD45A; growth arrest and DNA damage inducible alpha
4616 GADD45B; growth arrest and DNA damage inducible beta
10912 GADD45G; growth arrest and DNA damage inducible gamma
356 FASLG; Fas ligand
10018 BCL2L11; BCL2 like 11
8743 TNFSF10; TNF superfamily member 10
604 BCL6; BCL6 transcription repressor
664 BNIP3; BCL2 interacting protein 3
9140 ATG12; autophagy related 12
11337 GABARAP; GABA type A receptor-associated protein
23710 GABARAPL1; GABA type A receptor associated protein like 1
11345 GABARAPL2; GABA type A receptor associated protein like 2
847 CAT; catalase
6648 SOD2; superoxide dismutase 2
472 ATM; ATM serine/threonine kinase
5105 PCK1; phosphoenolpyruvate carboxykinase 1
5106 PCK2; phosphoenolpyruvate carboxykinase 2, mitochondrial
2538 G6PC1; glucose-6-phosphatase catalytic subunit 1
57818 G6PC2; glucose-6-phosphatase catalytic subunit 2
92579 G6PC3; glucose-6-phosphatase catalytic subunit 3
3575 IL7R; interleukin 7 receptor
10365 KLF2; KLF transcription factor 2
1901 S1PR1; sphingosine-1-phosphate receptor 1
8698 S1PR4; sphingosine-1-phosphate receptor 4
5896 RAG1; recombination activating 1
5897 RAG2; recombination activating 2
26260 FBXO25; F-box protein 25
114907 FBXO32; F-box protein 32
|
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04501 SMAD4; mothers against decapentaplegic homolog 4
K23605 SMAD3; mothers against decapentaplegic homolog 3
K07298 STK11; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K04468 NLK; nemo like kinase [EC:2.7.11.24]
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K11431 SETD7; [histone H3]-lysine4 N-methyltransferase [EC:2.1.1.364]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K11411 SIRT1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
K07191 SLC2A4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04411 STK4; serine/threonine kinase 4
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04526 INS; insulin
K04527 INSR; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K17446 IRS4; insulin receptor substrate 4
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K13302 SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
K13303 SGK2; serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
K13304 SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
K13304 SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K12358 FOXO4; forkhead box protein O4
K17847 FOXO6; forkhead box protein O6
K04603 GRM1; metabotropic glutamate receptor 1
K15010 HOMER; homer
K15010 HOMER; homer
K15010 HOMER; homer
K17848 AGAP2; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K05405 IL6; interleukin 6
K05443 IL10; interleukin 10
K04692 STAT3; signal transducer and activator of transcription 3
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K11434 PRMT1; type I protein arginine methyltransferase [EC:2.1.1.319]
K09385 FOXG; forkhead box protein G
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10146 CCNG2; cyclin G2
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K06623 CDKN2D; cyclin-dependent kinase inhibitor 2D
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K16332 RBL2; retinoblastoma-like protein 2
K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
K08861 PLK2; polo-like kinase 2 [EC:2.7.11.21]
K08862 PLK3; polo-like kinase 3 [EC:2.7.11.21]
K08863 PLK4; polo-like kinase 4 [EC:2.7.11.21]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K16341 BCL2L11; Bcl-2-like protein 11
K04721 TNFSF10; tumor necrosis factor ligand superfamily member 10
K15618 BCL6; B-cell lymphoma 6 protein
K15464 BNIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
K08336 ATG12; ubiquitin-like protein ATG12
K08341 GABARAP; GABA(A) receptor-associated protein
K08341 GABARAP; GABA(A) receptor-associated protein
K08341 GABARAP; GABA(A) receptor-associated protein
K03781 katE; catalase [EC:1.11.1.6]
K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K05072 IL7R; interleukin 7 receptor
K17845 KLF2; krueppel-like factor 2
K04288 S1PR1; sphingosine 1-phosphate receptor 1
K04293 S1PR4; sphingosine 1-phosphate receptor 4
K10628 RAG1; V(D)J recombination-activating protein 1 [EC:2.3.2.27]
K10988 RAG2; recombination-activating protein 2
K10305 FBXO25_32; F-box protein 25/32
K10305 FBXO25_32; F-box protein 25/32
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04020 Calcium signaling pathway [PATH:hsa04020]
|
04070 Phosphatidylinositol signaling system [PATH:hsa04070]
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04072 Phospholipase D signaling pathway [PATH:hsa04072]
|
04071 Sphingolipid signaling pathway [PATH:hsa04071]
|
04024 cAMP signaling pathway [PATH:hsa04024]
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7432 VIP; vasoactive intestinal peptide
1392 CRH; corticotropin releasing hormone
1081 CGA; glycoprotein hormones, alpha polypeptide
3972 LHB; luteinizing hormone subunit beta
170589 GPHA2; glycoprotein hormone subunit alpha 2
122876 GPHB5; glycoprotein hormone subunit beta 5
7252 TSHB; thyroid stimulating hormone subunit beta
5443 POMC; proopiomelanocortin
2641 GCG; glucagon
2695 GIP; gastric inhibitory polypeptide
2488 FSHB; follicle stimulating hormone subunit beta
4878 NPPA; natriuretic peptide A
116 ADCYAP1; adenylate cyclase activating polypeptide 1
153 ADRB1; adrenoceptor beta 1
154 ADRB2; adrenoceptor beta 2
1812 DRD1; dopamine receptor D1
1816 DRD5; dopamine receptor D5
135 ADORA2A; adenosine A2a receptor
3360 HTR4; 5-hydroxytryptamine receptor 4
3362 HTR6; 5-hydroxytryptamine receptor 6
5732 PTGER2; prostaglandin E receptor 2
117 ADCYAP1R1; ADCYAP receptor type I
7434 VIPR2; vasoactive intestinal peptide receptor 2
1394 CRHR1; corticotropin releasing hormone receptor 1
1395 CRHR2; corticotropin releasing hormone receptor 2
3973 LHCGR; luteinizing hormone/choriogonadotropin receptor
7253 TSHR; thyroid stimulating hormone receptor
4158 MC2R; melanocortin 2 receptor
2740 GLP1R; glucagon like peptide 1 receptor
2696 GIPR; gastric inhibitory polypeptide receptor
139760 GPR119; G protein-coupled receptor 119
2492 FSHR; follicle stimulating hormone receptor
4881 NPR1; natriuretic peptide receptor 1
2778 GNAS; GNAS complex locus
1906 EDN1; endothelin 1
1907 EDN2; endothelin 2
1908 EDN3; endothelin 3
6750 SST; somatostatin
4852 NPY; neuropeptide Y
51738 GHRL; ghrelin and obestatin prepropeptide
5020 OXT; oxytocin/neurophysin I prepropeptide
3350 HTR1A; 5-hydroxytryptamine receptor 1A
3351 HTR1B; 5-hydroxytryptamine receptor 1B
3352 HTR1D; 5-hydroxytryptamine receptor 1D
3354 HTR1E; 5-hydroxytryptamine receptor 1E
3355 HTR1F; 5-hydroxytryptamine receptor 1F
1128 CHRM1; cholinergic receptor muscarinic 1
1129 CHRM2; cholinergic receptor muscarinic 2
1813 DRD2; dopamine receptor D2
2550 GABBR1; gamma-aminobutyric acid type B receptor subunit 1
9568 GABBR2; gamma-aminobutyric acid type B receptor subunit 2
134 ADORA1; adenosine A1 receptor
1909 EDNRA; endothelin receptor type A
4886 NPY1R; neuropeptide Y receptor Y1
6751 SSTR1; somatostatin receptor 1
6752 SSTR2; somatostatin receptor 2
6755 SSTR5; somatostatin receptor 5
27198 HCAR1; hydroxycarboxylic acid receptor 1
338442 HCAR2; hydroxycarboxylic acid receptor 2
8843 HCAR3; hydroxycarboxylic acid receptor 3
2867 FFAR2; free fatty acid receptor 2
56670 SUCNR1; succinate receptor 1
5733 PTGER3; prostaglandin E receptor 3
5021 OXTR; oxytocin receptor
2693 GHSR; growth hormone secretagogue receptor
2770 GNAI1; G protein subunit alpha i1
2773 GNAI3; G protein subunit alpha i3
2771 GNAI2; G protein subunit alpha i2
107 ADCY1; adenylate cyclase 1
108 ADCY2; adenylate cyclase 2
109 ADCY3; adenylate cyclase 3
196883 ADCY4; adenylate cyclase 4
111 ADCY5; adenylate cyclase 5
112 ADCY6; adenylate cyclase 6
113 ADCY7; adenylate cyclase 7
114 ADCY8; adenylate cyclase 8
115 ADCY9; adenylate cyclase 9
55811 ADCY10; adenylate cyclase 10
1259 CNGA1; cyclic nucleotide gated channel subunit alpha 1
1260 CNGA2; cyclic nucleotide gated channel subunit alpha 2
1261 CNGA3; cyclic nucleotide gated channel subunit alpha 3
1262 CNGA4; cyclic nucleotide gated channel subunit alpha 4
1258 CNGB1; cyclic nucleotide gated channel subunit beta 1
54714 CNGB3; cyclic nucleotide gated channel subunit beta 3
810 CALML3; calmodulin like 3
805 CALM2; calmodulin 2
808 CALM3; calmodulin 3
801 CALM1; calmodulin 1
163688 CALML6; calmodulin like 6
51806 CALML5; calmodulin like 5
91860 CALML4; calmodulin like 4
815 CAMK2A; calcium/calmodulin dependent protein kinase II alpha
817 CAMK2D; calcium/calmodulin dependent protein kinase II delta
816 CAMK2B; calcium/calmodulin dependent protein kinase II beta
818 CAMK2G; calcium/calmodulin dependent protein kinase II gamma
814 CAMK4; calcium/calmodulin dependent protein kinase IV
11149 BVES; blood vessel epicardial substance
64091 POPDC2; popeye domain containing 2
64208 POPDC3; popeye domain containing 3
3776 KCNK2; potassium two pore domain channel subfamily K member 2
610 HCN2; hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2
10021 HCN4; hyperpolarization activated cyclic nucleotide gated potassium channel 4
10257 ABCC4; ATP binding cassette subfamily C member 4 (PEL blood group)
10411 RAPGEF3; Rap guanine nucleotide exchange factor 3
11069 RAPGEF4; Rap guanine nucleotide exchange factor 4
6237 RRAS; RAS related
22800 RRAS2; RAS related 2
5337 PLD1; phospholipase D1
5338 PLD2; phospholipase D2
51196 PLCE1; phospholipase C epsilon 1
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
5906 RAP1A; RAP1A, member of RAS oncogene family
5908 RAP1B; RAP1B, member of RAS oncogene family
7074 TIAM1; TIAM Rac1 associated GEF 1
10451 VAV3; vav guanine nucleotide exchange factor 3
7409 VAV1; vav guanine nucleotide exchange factor 1
7410 VAV2; vav guanine nucleotide exchange factor 2
5879 RAC1; Rac family small GTPase 1
5880 RAC2; Rac family small GTPase 2
5881 RAC3; Rac family small GTPase 3
5058 PAK1; p21 (RAC1) activated kinase 1
64411 ARAP3; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
387 RHOA; ras homolog family member A
4301 AFDN; afadin, adherens junction formation factor
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
84152 PPP1R1B; protein phosphatase 1 regulatory inhibitor subunit 1B
5499 PPP1CA; protein phosphatase 1 catalytic subunit alpha
5500 PPP1CB; protein phosphatase 1 catalytic subunit beta
5501 PPP1CC; protein phosphatase 1 catalytic subunit gamma
1385 CREB1; cAMP responsive element binding protein 1
10488 CREB3; cAMP responsive element binding protein 3
90993 CREB3L1; cAMP responsive element binding protein 3 like 1
64764 CREB3L2; cAMP responsive element binding protein 3 like 2
84699 CREB3L3; cAMP responsive element binding protein 3 like 3
148327 CREB3L4; cAMP responsive element binding protein 3 like 4
9586 CREB5; cAMP responsive element binding protein 5
1387 CREBBP; CREB binding protein
2033 EP300; E1A binding protein p300
627 BDNF; brain derived neurotrophic factor
2353 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
2737 GLI3; GLI family zinc finger 3
2735 GLI1; GLI family zinc finger 1
5727 PTCH1; patched 1
64399 HHIP; hedgehog interacting protein
4792 NFKBIA; NFKB inhibitor alpha
4790 NFKB1; nuclear factor kappa B subunit 1
5970 RELA; RELA proto-oncogene, NF-kB subunit
6662 SOX9; SRY-box transcription factor 9
268 AMH; anti-Mullerian hormone
5465 PPARA; peroxisome proliferator activated receptor alpha
8310 ACOX3; acyl-CoA oxidase 3, pristanoyl
51 ACOX1; acyl-CoA oxidase 1
4772 NFATC1; nuclear factor of activated T cells 1
2149 F2R; coagulation factor II thrombin receptor
572 BAD; BCL2 associated agonist of cell death
3991 LIPE; lipase E, hormone sensitive type
6093 ROCK1; Rho associated coiled-coil containing protein kinase 1
9475 ROCK2; Rho associated coiled-coil containing protein kinase 2
4659 PPP1R12A; protein phosphatase 1 regulatory subunit 12A
10398 MYL9; myosin light chain 9
7137 TNNI3; troponin I3, cardiac type
5350 PLN; phospholamban
487 ATP2A1; ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
489 ATP2A3; ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
488 ATP2A2; ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
6262 RYR2; ryanodine receptor 2
2902 GRIN1; glutamate ionotropic receptor NMDA type subunit 1
2903 GRIN2A; glutamate ionotropic receptor NMDA type subunit 2A
2904 GRIN2B; glutamate ionotropic receptor NMDA type subunit 2B
2905 GRIN2C; glutamate ionotropic receptor NMDA type subunit 2C
2906 GRIN2D; glutamate ionotropic receptor NMDA type subunit 2D
116443 GRIN3A; glutamate ionotropic receptor NMDA type subunit 3A
116444 GRIN3B; glutamate ionotropic receptor NMDA type subunit 3B
2890 GRIA1; glutamate ionotropic receptor AMPA type subunit 1
2891 GRIA2; glutamate ionotropic receptor AMPA type subunit 2
2892 GRIA3; glutamate ionotropic receptor AMPA type subunit 3
2893 GRIA4; glutamate ionotropic receptor AMPA type subunit 4
1080 CFTR; CF transmembrane conductance regulator
476 ATP1A1; ATPase Na+/K+ transporting subunit alpha 1
477 ATP1A2; ATPase Na+/K+ transporting subunit alpha 2
478 ATP1A3; ATPase Na+/K+ transporting subunit alpha 3
480 ATP1A4; ATPase Na+/K+ transporting subunit alpha 4
23439 ATP1B4; ATPase Na+/K+ transporting family member beta 4
481 ATP1B1; ATPase Na+/K+ transporting subunit beta 1
482 ATP1B2; ATPase Na+/K+ transporting subunit beta 2
483 ATP1B3; ATPase Na+/K+ transporting subunit beta 3
486 FXYD2; FXYD domain containing ion transport regulator 2
5348 FXYD1; FXYD domain containing ion transport regulator 1
6548 SLC9A1; solute carrier family 9 member A1
84876 ORAI1; ORAI calcium release-activated calcium modulator 1
490 ATP2B1; ATPase plasma membrane Ca2+ transporting 1
492 ATP2B3; ATPase plasma membrane Ca2+ transporting 3
493 ATP2B4; ATPase plasma membrane Ca2+ transporting 4
491 ATP2B2; ATPase plasma membrane Ca2+ transporting 2
775 CACNA1C; calcium voltage-gated channel subunit alpha1 C
776 CACNA1D; calcium voltage-gated channel subunit alpha1 D
778 CACNA1F; calcium voltage-gated channel subunit alpha1 F
779 CACNA1S; calcium voltage-gated channel subunit alpha1 S
5139 PDE3A; phosphodiesterase 3A
5140 PDE3B; phosphodiesterase 3B
5141 PDE4A; phosphodiesterase 4A
5142 PDE4B; phosphodiesterase 4B
5143 PDE4C; phosphodiesterase 4C
5144 PDE4D; phosphodiesterase 4D
10846 PDE10A; phosphodiesterase 10A
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K05264 VIP; vasoactive intestinal peptide
K05256 CRH; corticotropin-releasing hormone
K08522 CGA; glycoprotein hormones alpha chain
K08521 LHB; lutropin subunit beta
K25483 GPHA2; glycoprotein hormone alpha-2
K25484 GPHB5; glycoprotein hormone beta-5
K05251 TSHB; thyrotropin subunit beta
K05228 POMC; proopiomelanocortin
K05259 GCG; glucagon
K05258 GIP; gastric inhibitory polypeptide
K05250 FSHB; follitropin subunit beta
K12334 NPPA; natriuretic peptide A
K05262 ADCYAP; pituitary adenylate cyclase-activating polypeptide
K04141 ADRB1; adrenergic receptor beta-1
K04142 ADRB2; adrenergic receptor beta-2
K04144 DRD1; dopamine receptor D1
K05840 DRD5; dopamine receptor D5
K04266 ADORA2A; adenosine receptor A2a
K04160 HTR4; 5-hydroxytryptamine receptor 4
K04162 HTR6; 5-hydroxytryptamine receptor 6
K04259 PTGER2; prostaglandin E receptor 2
K04587 ADCYAP1R1; pituitary adenylate cyclase-activating polypeptide type I receptor
K04590 VIPR2; vasoactive intestinal peptide receptor 2
K04578 CRHR1; corticotropin releasing hormone receptor 1
K04579 CRHR2; corticotropin releasing hormone receptor 2
K04248 LHCGR; lutropin-choriogonadotropic hormone receptor
K04249 TSHR; thyrotropin receptor
K04200 MC2R; melanocortin 2 receptor
K04581 GLP1R; glucagon-like peptide 1 receptor
K04580 GIPR; gastric inhibitory polypeptide receptor
K08424 GPR119; glucose-dependent insulinotropic receptor
K04247 FSHR; follicle stimulating hormone receptor
K12323 ANPRA; atrial natriuretic peptide receptor A [EC:4.6.1.2]
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K16366 EDN1; endothelin-1
K16367 EDN2; endothelin-2
K05227 EDN3; endothelin-3
K05237 SST; somatostatin
K05232 NPY; neuropeptide Y
K05254 GHRL; ghrelin
K05243 OXT; oxytocin-neurophysin 1
K04153 HTR1; 5-hydroxytryptamine receptor 1
K04153 HTR1; 5-hydroxytryptamine receptor 1
K04153 HTR1; 5-hydroxytryptamine receptor 1
K04153 HTR1; 5-hydroxytryptamine receptor 1
K04153 HTR1; 5-hydroxytryptamine receptor 1
K04129 CHRM1; muscarinic acetylcholine receptor M1
K04130 CHRM2; muscarinic acetylcholine receptor M2
K04145 DRD2; dopamine receptor D2
K04615 GABBR; gamma-aminobutyric acid type B receptor
K04615 GABBR; gamma-aminobutyric acid type B receptor
K04265 ADORA1; adenosine receptor A1
K04197 EDNRA; endothelin receptor type A
K04204 NPY1R; neuropeptide Y receptor type 1
K04217 SSTR1; somatostatin receptor 1
K04218 SSTR2; somatostatin receptor 2
K04221 SSTR5; somatostatin receptor 5
K08401 HCAR1; hydroxycarboxylic acid receptor 1
K08402 HCAR2_3; hydroxycarboxylic acid receptor 2/3
K08402 HCAR2_3; hydroxycarboxylic acid receptor 2/3
K04328 FFAR2; free fatty acid receptor 2
K10042 SUCNR1; succinate receptor 1
K04260 PTGER3; prostaglandin E receptor 3
K04229 OXTR; oxytocin receptor
K04284 GHSR; growth hormone secretagogue receptor
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K11265 ADCY10; adenylate cyclase 10 [EC:4.6.1.1]
K04948 CNGA1; cyclic nucleotide gated channel alpha 1
K04949 CNGA2; cyclic nucleotide gated channel alpha 2
K04950 CNGA3; cyclic nucleotide gated channel alpha 3
K04951 CNGA4; cyclic nucleotide gated channel alpha 4
K04952 CNGB1; cyclic nucleotide gated channel beta 1
K04953 CNGB3; cyclic nucleotide gated channel beta 3
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K05869 CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
K21108 BVES; blood vessel epicardial substance
K26206 POPDC2; popeye domain-containing protein 2
K26207 POPDC3; popeye domain-containing protein 3
K04913 KCNK2; potassium channel subfamily K member 2
K04955 HCN2; hyperpolarization activated cyclic nucleotide-gated potassium channel 2
K04957 HCN4; hyperpolarization activated cyclic nucleotide-gated potassium channel 4
K05673 ABCC4; ATP-binding cassette, subfamily C (CFTR/MRP), member 4
K08014 RAPGEF3; Rap guanine nucleotide exchange factor 3
K04351 RAPGEF4; Rap guanine nucleotide exchange factor 4
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2; Ras-related protein R-Ras2
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K05860 PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K05731 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K12490 ARAP3; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
K04513 RHOA; Ras homolog gene family, member A
K05702 AF6; afadin
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K15494 PPP1R1B; protein phosphatase 1 regulatory subunit 1B
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5; cyclic AMP-responsive element-binding protein 5
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04355 BDNF; brain-derived neurotrophic factor
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K06230 GLI3; zinc finger protein GLI3
K16797 GLI1; zinc finger protein GLI1
K06225 PTCH1; patched 1
K06231 HHIP; hedgehog interacting protein
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K18435 SOX9; transcription factor SOX9 (SOX group E)
K04665 AMH; anti-mullerian hormone
K07294 NR1C1; peroxisome proliferator-activated receptor alpha
K00232 E1.3.3.6; acyl-CoA oxidase [EC:1.3.3.6]
K00232 E1.3.3.6; acyl-CoA oxidase [EC:1.3.3.6]
K04446 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
K03914 F2R; coagulation factor II (thrombin) receptor
K02158 BAD; Bcl-2-antagonist of cell death
K07188 LIPE; hormone-sensitive lipase [EC:3.1.1.79]
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K06270 PPP1R12A; protein phosphatase 1 regulatory subunit 12A
K12755 MYL9; myosin regulatory light chain 9
K12044 TNNI3; troponin I, cardiac muscle
K05852 PLN; phospholamban
K05853 ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
K05853 ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
K05853 ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
K04962 RYR2; ryanodine receptor 2
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K05211 GRIN2C; glutamate receptor ionotropic, NMDA 2C
K05212 GRIN2D; glutamate receptor ionotropic, NMDA 2D
K05213 GRIN3A; glutamate receptor ionotropic, NMDA 3A
K05214 GRIN3B; glutamate receptor ionotropic, NMDA 3B
K05197 GRIA1; glutamate receptor 1
K05198 GRIA2; glutamate receptor 2
K05199 GRIA3; glutamate receptor 3
K05200 GRIA4; glutamate receptor 4
K05031 CFTR; cystic fibrosis transmembrane conductance regulator [EC:5.6.1.6]
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
K01540 ATP1B; sodium/potassium-transporting ATPase subunit beta
K01540 ATP1B; sodium/potassium-transporting ATPase subunit beta
K01540 ATP1B; sodium/potassium-transporting ATPase subunit beta
K01540 ATP1B; sodium/potassium-transporting ATPase subunit beta
K01538 FXYD2; sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)
K13360 FXYD1; FXYD domain-containing ion transport regulator 1
K05742 SLC9A1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
K16056 ORAI1; calcium release-activated calcium channel protein 1
K05850 ATP2B; P-type Ca2+ transporter type 2B [EC:7.2.2.10]
K05850 ATP2B; P-type Ca2+ transporter type 2B [EC:7.2.2.10]
K05850 ATP2B; P-type Ca2+ transporter type 2B [EC:7.2.2.10]
K05850 ATP2B; P-type Ca2+ transporter type 2B [EC:7.2.2.10]
K04850 CACNA1C; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S; voltage-dependent calcium channel L type alpha-1S
K19021 PDE3A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A [EC:3.1.4.17]
K13296 PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:3.1.4.17]
K13293 PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
K13293 PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
K13293 PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
K13293 PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
K18438 PDE10; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:3.1.4.17 3.1.4.35]
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04022 cGMP-PKG signaling pathway [PATH:hsa04022]
|
04151 PI3K-Akt signaling pathway [PATH:hsa04151]
|
04152 AMPK signaling pathway [PATH:hsa04152]
|
04150 mTOR signaling pathway [PATH:hsa04150]
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8140 SLC7A5; solute carrier family 7 member 5
6520 SLC3A2; solute carrier family 3 member 2
153129 SLC38A9; solute carrier family 38 member 9
523 ATP6V1A; ATPase H+ transporting V1 subunit A
525 ATP6V1B1; ATPase H+ transporting V1 subunit B1
526 ATP6V1B2; ATPase H+ transporting V1 subunit B2
245973 ATP6V1C2; ATPase H+ transporting V1 subunit C2
528 ATP6V1C1; ATPase H+ transporting V1 subunit C1
51382 ATP6V1D; ATPase H+ transporting V1 subunit D
90423 ATP6V1E2; ATPase H+ transporting V1 subunit E2
529 ATP6V1E1; ATPase H+ transporting V1 subunit E1
9296 ATP6V1F; ATPase H+ transporting V1 subunit F
9550 ATP6V1G1; ATPase H+ transporting V1 subunit G1
127124 ATP6V1G3; ATPase H+ transporting V1 subunit G3
534 ATP6V1G2; ATPase H+ transporting V1 subunit G2
51606 ATP6V1H; ATPase H+ transporting V1 subunit H
55004 LAMTOR1; late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
28956 LAMTOR2; late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
8649 LAMTOR3; late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
389541 LAMTOR4; late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
10542 LAMTOR5; late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
201163 FLCN; folliculin
96459 FNIP1; folliculin interacting protein 1
57600 FNIP2; folliculin interacting protein 2
10670 RRAGA; Ras related GTP binding A
10325 RRAGB; Ras related GTP binding B
64121 RRAGC; Ras related GTP binding C
58528 RRAGD; Ras related GTP binding D
83667 SESN2; sestrin 2
652968 CASTOR1; cytosolic arginine sensor for mTORC1 subunit 1
729438 CASTOR2; cytosolic arginine sensor for mTORC1 subunit 2
54468 MIOS; meiosis regulator for oocyte development
81929 SEH1L; SEH1 like nucleoporin
84219 WDR24; WD repeat domain 24
79726 WDR59; WD repeat domain 59
6396 SEC13; SEC13 homolog, nuclear pore and COPII coat complex component
9681 DEPDC5; DEP domain containing 5, GATOR1 subcomplex subunit
10641 NPRL2; NPR2 like, GATOR1 complex subunit
8131 NPRL3; NPR3 like, GATOR1 complex subunit
6502 SKP2; S-phase kinase associated protein 2
220441 RNF152; ring finger protein 152
57521 RPTOR; regulatory associated protein of MTOR complex 1
84335 AKT1S1; AKT1 substrate 1
2475 MTOR; mechanistic target of rapamycin kinase
64798 DEPTOR; DEP domain containing MTOR interacting protein
64223 MLST8; MTOR associated protein, LST8 homolog
9894 TELO2; telomere maintenance 2
9675 TTI1; TELO2 interacting protein 1
6249 CLIP1; CAP-Gly domain containing linker protein 1
2887 GRB10; growth factor receptor bound protein 10
23175 LPIN1; lipin 1
64900 LPIN3; lipin 3
9663 LPIN2; lipin 2
8408 ULK1; unc-51 like autophagy activating kinase 1
9706 ULK2; unc-51 like autophagy activating kinase 2
1978 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
1977 EIF4E; eukaryotic translation initiation factor 4E
9470 EIF4E2; eukaryotic translation initiation factor 4E family member 2
253314 EIF4E1B; eukaryotic translation initiation factor 4E family member 1B
6198 RPS6KB1; ribosomal protein S6 kinase B1
6199 RPS6KB2; ribosomal protein S6 kinase B2
1975 EIF4B; eukaryotic translation initiation factor 4B
6194 RPS6; ribosomal protein S6
92335 STRADA; STE20 related adaptor alpha
55437 STRADB; STE20 related adaptor beta
6794 STK11; serine/threonine kinase 11
51719 CAB39; calcium binding protein 39
81617 CAB39L; calcium binding protein 39 like
5562 PRKAA1; protein kinase AMP-activated catalytic subunit alpha 1
5563 PRKAA2; protein kinase AMP-activated catalytic subunit alpha 2
7248 TSC1; TSC complex subunit 1
7249 TSC2; TSC complex subunit 2
51256 TBC1D7; TBC1 domain family member 7
107080638 TBC1D7-LOC100130357 readthrough
6009 RHEB; Ras homolog, mTORC1 binding
54541 DDIT4; DNA damage inducible transcript 4
7471 WNT1; Wnt family member 1
7472 WNT2; Wnt family member 2
7482 WNT2B; Wnt family member 2B
7473 WNT3; Wnt family member 3
89780 WNT3A; Wnt family member 3A
54361 WNT4; Wnt family member 4
7474 WNT5A; Wnt family member 5A
81029 WNT5B; Wnt family member 5B
7475 WNT6; Wnt family member 6
7476 WNT7A; Wnt family member 7A
7477 WNT7B; Wnt family member 7B
7478 WNT8A; Wnt family member 8A
7479 WNT8B; Wnt family member 8B
7483 WNT9A; Wnt family member 9A
7484 WNT9B; Wnt family member 9B
7480 WNT10B; Wnt family member 10B
80326 WNT10A; Wnt family member 10A
7481 WNT11; Wnt family member 11
51384 WNT16; Wnt family member 16
8321 FZD1; frizzled class receptor 1
8324 FZD7; frizzled class receptor 7
2535 FZD2; frizzled class receptor 2
7976 FZD3; frizzled class receptor 3
8322 FZD4; frizzled class receptor 4
7855 FZD5; frizzled class receptor 5
8325 FZD8; frizzled class receptor 8
8323 FZD6; frizzled class receptor 6
11211 FZD10; frizzled class receptor 10
8326 FZD9; frizzled class receptor 9
4041 LRP5; LDL receptor related protein 5
4040 LRP6; LDL receptor related protein 6
1857 DVL3; dishevelled segment polarity protein 3
1856 DVL2; dishevelled segment polarity protein 2
1855 DVL1; dishevelled segment polarity protein 1
2932 GSK3B; glycogen synthase kinase 3 beta
7124 TNF; tumor necrosis factor
7132 TNFRSF1A; TNF receptor superfamily member 1A
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
3630 INS; insulin
3479 IGF1; insulin like growth factor 1
3643 INSR; insulin receptor
3480 IGF1R; insulin like growth factor 1 receptor
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
6197 RPS6KA3; ribosomal protein S6 kinase A3
6195 RPS6KA1; ribosomal protein S6 kinase A1
6196 RPS6KA2; ribosomal protein S6 kinase A2
27330 RPS6KA6; ribosomal protein S6 kinase A6
3667 IRS1; insulin receptor substrate 1
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5728 PTEN; phosphatase and tensin homolog
5170 PDPK1; 3-phosphoinositide dependent protein kinase 1
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
79109 MAPKAP1; MAPK associated protein 1
253260 RICTOR; RPTOR independent companion of MTOR complex 2
55615 PRR5; proline rich 5
79899 PRR5L; proline rich 5 like
387 RHOA; ras homolog family member A
5578 PRKCA; protein kinase C alpha
5579 PRKCB; protein kinase C beta
5582 PRKCG; protein kinase C gamma
6446 SGK1; serum/glucocorticoid regulated kinase 1
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K13780 SLC7A5; solute carrier family 7 (L-type amino acid transporter), member 5
K06519 SLC3A2; solute carrier family 3, member 2
K14995 SLC38A9; solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 9
K02145 ATPeV1A; V-type H+-transporting ATPase subunit A [EC:7.1.2.2]
K02147 ATPeV1B; V-type H+-transporting ATPase subunit B
K02147 ATPeV1B; V-type H+-transporting ATPase subunit B
K02148 ATPeV1C; V-type H+-transporting ATPase subunit C
K02148 ATPeV1C; V-type H+-transporting ATPase subunit C
K02149 ATPeV1D; V-type H+-transporting ATPase subunit D
K02150 ATPeV1E; V-type H+-transporting ATPase subunit E
K02150 ATPeV1E; V-type H+-transporting ATPase subunit E
K02151 ATPeV1F; V-type H+-transporting ATPase subunit F
K02152 ATPeV1G; V-type H+-transporting ATPase subunit G
K02152 ATPeV1G; V-type H+-transporting ATPase subunit G
K02152 ATPeV1G; V-type H+-transporting ATPase subunit G
K02144 ATPeV1H; V-type H+-transporting ATPase subunit H
K20397 LAMTOR1; ragulator complex protein LAMTOR1
K20398 LAMTOR2; ragulator complex protein LAMTOR2
K04370 LAMTOR3; ragulator complex protein LAMTOR3
K20399 LAMTOR4; ragulator complex protein LAMTOR4
K16344 LAMTOR5; ragulator complex protein LAMTOR5
K09594 FLCN; folliculin
K20400 FNIP1; folliculin-interacting protein 1
K20401 FNIP2; folliculin-interacting protein 2
K16185 RRAGA_B; Ras-related GTP-binding protein A/B
K16185 RRAGA_B; Ras-related GTP-binding protein A/B
K16186 RRAGC_D; Ras-related GTP-binding protein C/D
K16186 RRAGC_D; Ras-related GTP-binding protein C/D
K20394 SESN2; sestrin 2
K23080 CASTOR1; cytosolic arginine sensor for mTORC1 subunit 1
K23081 CASTOR2; cytosolic arginine sensor for mTORC1 subunit 2
K20407 MIOS; SEA/GATOR complex protein SEA4/MIOS
K14299 SEH1; nucleoporin SEH1
K20408 WDR24; SEA/GATOR complex protein SEA2/WDR24
K20409 WDR59; SEA/GATOR complex protein SEA3/WDR59
K14004 SEC13; protein transport protein SEC13
K20404 DEPDC5; SEA/GATOR complex protein SEA1/DEPDC5
K20405 NPRL2; nitrogen permease regulator 2
K20406 NPRL3; nitrogen permease regulator 3
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K15705 RNF152; E3 ubiquitin-protein ligase RNF152 [EC:2.3.2.27]
K07204 RAPTOR; regulatory associated protein of mTOR
K16184 AKT1S1; proline-rich AKT1 substrate 1
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K20402 DEPTOR; DEP domain-containing mTOR-interacting protein
K08266 MLST8; target of rapamycin complex subunit LST8
K11137 TELO2; telomere length regulation protein
K20403 TTI1; TELO2-interacting protein 1
K10421 CLIP1; CAP-Gly domain-containing linker protein 1
K20064 GRB10; growth factor receptor-bound protein 10
K15728 LPIN; phosphatidate phosphatase LPIN [EC:3.1.3.4]
K15728 LPIN; phosphatidate phosphatase LPIN [EC:3.1.3.4]
K15728 LPIN; phosphatidate phosphatase LPIN [EC:3.1.3.4]
K21357 ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
K08269 ULK2; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K03259 EIF4E; translation initiation factor 4E
K03259 EIF4E; translation initiation factor 4E
K03259 EIF4E; translation initiation factor 4E
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K03258 EIF4B; translation initiation factor 4B
K02991 RP-S6e; small subunit ribosomal protein S6e
K08271 STRADA; STE20-related kinase adapter protein alpha
K17532 STRADB; STE20-related kinase adapter protein beta
K07298 STK11; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K08272 CAB39; calcium binding protein 39
K08272 CAB39; calcium binding protein 39
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K20396 TBC1D7; TBC1 domain family member 7
K20396 TBC1D7; TBC1 domain family member 7
K07208 RHEB; Ras homolog enriched in brain
K08270 DDIT4; DNA-damage-inducible transcript 4
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K03156 TNF; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04526 INS; insulin
K05459 IGF1; insulin-like growth factor 1
K04527 INSR; insulin receptor [EC:2.7.10.1]
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K16172 IRS1; insulin receptor substrate 1
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K20410 MAPKAP1; target of rapamycin complex 2 subunit MAPKAP1/AVO1
K08267 RICTOR; rapamycin-insensitive companion of mTOR
K20411 PRR5; proline-rich protein 5
K20411 PRR5; proline-rich protein 5
K04513 RHOA; Ras homolog gene family, member A
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K13302 SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
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04075 Plant hormone signal transduction
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09133 Signaling molecules and interaction
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09140 Cellular Processes
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09141 Transport and catabolism
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09143 Cell growth and death
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09144 Cellular community - eukaryotes
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04510 Focal adhesion [PATH:hsa04510]
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1277 COL1A1; collagen type I alpha 1 chain
1278 COL1A2; collagen type I alpha 2 chain
1280 COL2A1; collagen type II alpha 1 chain
1284 COL4A2; collagen type IV alpha 2 chain
1286 COL4A4; collagen type IV alpha 4 chain
1288 COL4A6; collagen type IV alpha 6 chain
1282 COL4A1; collagen type IV alpha 1 chain
1287 COL4A5; collagen type IV alpha 5 chain
1285 COL4A3; collagen type IV alpha 3 chain
1291 COL6A1; collagen type VI alpha 1 chain
1292 COL6A2; collagen type VI alpha 2 chain
1293 COL6A3; collagen type VI alpha 3 chain
131873 COL6A6; collagen type VI alpha 6 chain
256076 COL6A5; collagen type VI alpha 5 chain
1297 COL9A1; collagen type IX alpha 1 chain
1298 COL9A2; collagen type IX alpha 2 chain
1299 COL9A3; collagen type IX alpha 3 chain
284217 LAMA1; laminin subunit alpha 1
3908 LAMA2; laminin subunit alpha 2
3909 LAMA3; laminin subunit alpha 3
3911 LAMA5; laminin subunit alpha 5
3910 LAMA4; laminin subunit alpha 4
3912 LAMB1; laminin subunit beta 1
3913 LAMB2; laminin subunit beta 2
3914 LAMB3; laminin subunit beta 3
22798 LAMB4; laminin subunit beta 4
3915 LAMC1; laminin subunit gamma 1
3918 LAMC2; laminin subunit gamma 2
10319 LAMC3; laminin subunit gamma 3
1101 CHAD; chondroadherin
5649 RELN; reelin
7057 THBS1; thrombospondin 1
1311 COMP; cartilage oligomeric matrix protein
7058 THBS2; thrombospondin 2
7059 THBS3; thrombospondin 3
7060 THBS4; thrombospondin 4
2335 FN1; fibronectin 1
6696 SPP1; secreted phosphoprotein 1
7448 VTN; vitronectin
3371 TNC; tenascin C
63923 TNN; tenascin N
7143 TNR; tenascin R
7148 TNXB; tenascin XB
7450 VWF; von Willebrand factor
3381 IBSP; integrin binding sialoprotein
3672 ITGA1; integrin subunit alpha 1
3673 ITGA2; integrin subunit alpha 2
3674 ITGA2B; integrin subunit alpha 2b
3675 ITGA3; integrin subunit alpha 3
3676 ITGA4; integrin subunit alpha 4
3678 ITGA5; integrin subunit alpha 5
3655 ITGA6; integrin subunit alpha 6
3679 ITGA7; integrin subunit alpha 7
8516 ITGA8; integrin subunit alpha 8
3680 ITGA9; integrin subunit alpha 9
8515 ITGA10; integrin subunit alpha 10
22801 ITGA11; integrin subunit alpha 11
3685 ITGAV; integrin subunit alpha V
3688 ITGB1; integrin subunit beta 1
3690 ITGB3; integrin subunit beta 3
3691 ITGB4; integrin subunit beta 4
3693 ITGB5; integrin subunit beta 5
3694 ITGB6; integrin subunit beta 6
3695 ITGB7; integrin subunit beta 7
3696 ITGB8; integrin subunit beta 8
2013 EMP2; epithelial membrane protein 2
5154 PDGFA; platelet derived growth factor subunit A
5155 PDGFB; platelet derived growth factor subunit B
56034 PDGFC; platelet derived growth factor C
80310 PDGFD; platelet derived growth factor D
1950 EGF; epidermal growth factor
3479 IGF1; insulin like growth factor 1
7422 VEGFA; vascular endothelial growth factor A
7423 VEGFB; vascular endothelial growth factor B
5228 PGF; placental growth factor
7424 VEGFC; vascular endothelial growth factor C
2277 VEGFD; vascular endothelial growth factor D
3082 HGF; hepatocyte growth factor
5156 PDGFRA; platelet derived growth factor receptor alpha
5159 PDGFRB; platelet derived growth factor receptor beta
3480 IGF1R; insulin like growth factor 1 receptor
3791 KDR; kinase insert domain receptor
1956 EGFR; epidermal growth factor receptor
2321 FLT1; fms related receptor tyrosine kinase 1
2324 FLT4; fms related receptor tyrosine kinase 4
4233 MET; MET proto-oncogene, receptor tyrosine kinase
2064 ERBB2; erb-b2 receptor tyrosine kinase 2
2012 EMP1; epithelial membrane protein 1
6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase
2909 ARHGAP35; Rho GTPase activating protein 35
394 ARHGAP5; Rho GTPase activating protein 5
387 RHOA; ras homolog family member A
1729 DIAPH1; diaphanous related formin 1
6093 ROCK1; Rho associated coiled-coil containing protein kinase 1
9475 ROCK2; Rho associated coiled-coil containing protein kinase 2
4633 MYL2; myosin light chain 2
4636 MYL5; myosin light chain 5
58498 MYL7; myosin light chain 7
10398 MYL9; myosin light chain 9
93408 MYL10; myosin light chain 10
103910 MYL12B; myosin light chain 12B
10627 MYL12A; myosin light chain 12A
29895 MYL11; myosin light chain 11
5499 PPP1CA; protein phosphatase 1 catalytic subunit alpha
5500 PPP1CB; protein phosphatase 1 catalytic subunit beta
5501 PPP1CC; protein phosphatase 1 catalytic subunit gamma
4659 PPP1R12A; protein phosphatase 1 regulatory subunit 12A
4660 PPP1R12B; protein phosphatase 1 regulatory subunit 12B
54776 PPP1R12C; protein phosphatase 1 regulatory subunit 12C
4638 MYLK; myosin light chain kinase
85366 MYLK2; myosin light chain kinase 2
91807 MYLK3; myosin light chain kinase 3
340156 MYLK4; myosin light chain kinase family member 4
23396 PIP5K1C; phosphatidylinositol-4-phosphate 5-kinase type 1 gamma
8394 PIP5K1A; phosphatidylinositol-4-phosphate 5-kinase type 1 alpha
8395 PIP5K1B; phosphatidylinositol-4-phosphate 5-kinase type 1 beta
71 ACTG1; actin gamma 1
60 ACTB; actin beta
5923 RASGRF1; Ras protein specific guanine nucleotide releasing factor 1
824 CAPN2; calpain 2
87 ACTN1; actinin alpha 1
81 ACTN4; actinin alpha 4
7094 TLN1; talin 1
83660 TLN2; talin 2
2316 FLNA; filamin A
2317 FLNB; filamin B
5829 PXN; paxillin
3611 ILK; integrin linked kinase
7791 ZYX; zyxin
7408 VASP; vasodilator stimulated phosphoprotein
7414 VCL; vinculin
29780 PARVB; parvin beta
55742 PARVA; parvin alpha
64098 PARVG; parvin gamma
5170 PDPK1; 3-phosphoinositide dependent protein kinase 1
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
2932 GSK3B; glycogen synthase kinase 3 beta
1499 CTNNB1; catenin beta 1
5578 PRKCA; protein kinase C alpha
5579 PRKCB; protein kinase C beta
5582 PRKCG; protein kinase C gamma
5747 PTK2; protein tyrosine kinase 2
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
5728 PTEN; phosphatase and tensin homolog
10451 VAV3; vav guanine nucleotide exchange factor 3
7409 VAV1; vav guanine nucleotide exchange factor 1
7410 VAV2; vav guanine nucleotide exchange factor 2
5879 RAC1; Rac family small GTPase 1
5880 RAC2; Rac family small GTPase 2
5881 RAC3; Rac family small GTPase 3
5058 PAK1; p21 (RAC1) activated kinase 1
5062 PAK2; p21 (RAC1) activated kinase 2
5063 PAK3; p21 (RAC1) activated kinase 3
10298 PAK4; p21 (RAC1) activated kinase 4
57144 PAK5; p21 (RAC1) activated kinase 5
56924 PAK6; p21 (RAC1) activated kinase 6
106821730 BUB1B-PAK6; BUB1B-PAK6 readthrough
998 CDC42; cell division cycle 42
9564 BCAR1; BCAR1 scaffold protein, Cas family member
1398 CRK; CRK proto-oncogene, adaptor protein
1399 CRKL; CRK like proto-oncogene, adaptor protein
1793 DOCK1; dedicator of cytokinesis 1
2889 RAPGEF1; Rap guanine nucleotide exchange factor 1
5906 RAP1A; RAP1A, member of RAS oncogene family
5908 RAP1B; RAP1B, member of RAS oncogene family
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
857 CAV1; caveolin 1
858 CAV2; caveolin 2
859 CAV3; caveolin 3
2534 FYN; FYN proto-oncogene, Src family tyrosine kinase
6464 SHC1; SHC adaptor protein 1
25759 SHC2; SHC adaptor protein 2
53358 SHC3; SHC adaptor protein 3
399694 SHC4; SHC adaptor protein 4
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
2002 ELK1; ETS transcription factor ELK1
595 CCND1; cyclin D1
894 CCND2; cyclin D2
896 CCND3; cyclin D3
329 BIRC2; baculoviral IAP repeat containing 2
330 BIRC3; baculoviral IAP repeat containing 3
331 XIAP; X-linked inhibitor of apoptosis
572 BAD; BCL2 associated agonist of cell death
596 BCL2; BCL2 apoptosis regulator
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K06236 COL1A; collagen type I alpha
K06236 COL1A; collagen type I alpha
K19719 COL2A; collagen type II alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06238 COL6A; collagen type VI alpha
K06238 COL6A; collagen type VI alpha
K06238 COL6A; collagen type VI alpha
K06238 COL6A; collagen type VI alpha
K06238 COL6A; collagen type VI alpha
K08131 COL9A; collagen type IX alpha
K08131 COL9A; collagen type IX alpha
K08131 COL9A; collagen type IX alpha
K05637 LAMA1_2; laminin, alpha 1/2
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K06248 CHAD; chondroadherin
K06249 RELN; reelin [EC:3.4.21.-]
K16857 THBS1; thrombospondin 1
K04659 THBS2S; thrombospondin 2/3/4/5
K04659 THBS2S; thrombospondin 2/3/4/5
K04659 THBS2S; thrombospondin 2/3/4/5
K04659 THBS2S; thrombospondin 2/3/4/5
K05717 FN1; fibronectin 1
K06250 SPP1; secreted phosphoprotein 1
K06251 VTN; vitronectin
K06252 TN; tenascin
K06252 TN; tenascin
K06252 TN; tenascin
K06252 TN; tenascin
K03900 VWF; von Willebrand factor
K06253 IBSP; integrin binding sialoprotein
K06480 ITGA1; integrin alpha 1
K06481 ITGA2; integrin alpha 2
K06476 ITGA2B; integrin alpha 2B
K06482 ITGA3; integrin alpha 3
K06483 ITGA4; integrin alpha 4
K06484 ITGA5; integrin alpha 5
K06485 ITGA6; integrin alpha 6
K06583 ITGA7; integrin alpha 7
K06584 ITGA8; integrin alpha 8
K06585 ITGA9; integrin alpha 9
K06586 ITGA10; integrin alpha 10
K06587 ITGA11; integrin alpha 11
K06487 ITGAV; integrin alpha V
K05719 ITGB1; integrin beta 1
K06493 ITGB3; integrin beta 3
K06525 ITGB4; integrin beta 4
K06588 ITGB5; integrin beta 5
K06589 ITGB6; integrin beta 6
K06590 ITGB7; integrin beta 7
K06591 ITGB8; integrin beta 8
K26256 EMP2; epithelial membrane protein 2
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05450 PDGFC_D; platelet derived growth factor C/D
K04357 EGF; epidermal growth factor
K05459 IGF1; insulin-like growth factor 1
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05460 HGF; hepatocyte growth factor
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K05098 KDR; kinase insert domain protein receptor [EC:2.7.10.1]
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05096 FLT1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05097 FLT4; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K26255 EMP1; epithelial membrane protein 1
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05732 ARHGAP35; glucocorticoid receptor DNA-binding factor 1
K13709 ARHGAP5; Rho GTPase-activating protein 5
K04513 RHOA; Ras homolog gene family, member A
K05740 DIAPH1; diaphanous 1
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10351 MYL2; myosin regulatory light chain 2
K12753 MYL5; myosin regulatory light chain 5
K12754 MYL7; myosin regulatory light chain 7
K12755 MYL9; myosin regulatory light chain 9
K12756 MYL10; myosin regulatory light chain 10
K12757 MYL12; myosin regulatory light chain 12
K12757 MYL12; myosin regulatory light chain 12
K12758 MYLPF; fast skeletal myosin light chain 2
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06270 PPP1R12A; protein phosphatase 1 regulatory subunit 12A
K12329 PPP1R12B; protein phosphatase 1 regulatory subunit 12B
K17457 PPP1R12C; protein phosphatase 1 regulatory subunit 12C
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
K04349 RASGRF1; Ras-specific guanine nucleotide-releasing factor 1
K03853 CAPN2; calpain-2 [EC:3.4.22.53]
K05699 ACTN1_4; actinin alpha 1/4
K05699 ACTN1_4; actinin alpha 1/4
K06271 TLN; talin
K06271 TLN; talin
K04437 FLNA; filamin-A
K27392 FLNB; filamin-B
K05760 PXN; paxillin
K06272 ILK; integrin-linked kinase [EC:2.7.11.1]
K06273 ZYX; zyxin
K06274 VASP; vasodilator-stimulated phosphoprotein
K05700 VCL; vinculin
K06275 PARV; parvin
K06275 PARV; parvin
K06275 PARV; parvin
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02105 CTNNB1; catenin beta 1
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K04393 CDC42; cell division control protein 42
K05726 BCAR1; breast cancer anti-estrogen resistance 1
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K13708 DOCK1; dedicator of cytokinesis protein 1
K06277 RAPGEF1; Rap guanine nucleotide exchange factor 1
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K06278 CAV1; caveolin 1
K12958 CAV2; caveolin 2
K12959 CAV3; caveolin 3
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04375 ELK1; ETS domain-containing protein Elk-1
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K02158 BAD; Bcl-2-antagonist of cell death
K02161 BCL2; apoptosis regulator Bcl-2
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04520 Adherens junction [PATH:hsa04520]
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04530 Tight junction [PATH:hsa04530]
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04540 Gap junction [PATH:hsa04540]
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04550 Signaling pathways regulating pluripotency of stem cells [PATH:hsa04550]
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09145 Cellular community - prokaryotes
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09142 Cell motility
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02030 Bacterial chemotaxis
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02040 Flagellar assembly
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04814 Motor proteins [PATH:hsa04814]
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04820 Cytoskeleton in muscle cells [PATH:hsa04820]
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04810 Regulation of actin cytoskeleton [PATH:hsa04810]
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1902 LPAR1; lysophosphatidic acid receptor 1
9170 LPAR2; lysophosphatidic acid receptor 2
2846 LPAR4; lysophosphatidic acid receptor 4
57121 LPAR5; lysophosphatidic acid receptor 5
6387 CXCL12; C-X-C motif chemokine ligand 12
7852 CXCR4; C-X-C motif chemokine receptor 4
2147 F2; coagulation factor II, thrombin
2149 F2R; coagulation factor II thrombin receptor
3630 INS; insulin
1950 EGF; epidermal growth factor
2246 FGF1; fibroblast growth factor 1
2247 FGF2; fibroblast growth factor 2
2248 FGF3; fibroblast growth factor 3
2249 FGF4; fibroblast growth factor 4
8822 FGF17; fibroblast growth factor 17
2251 FGF6; fibroblast growth factor 6
2252 FGF7; fibroblast growth factor 7
2253 FGF8; fibroblast growth factor 8
2254 FGF9; fibroblast growth factor 9
2255 FGF10; fibroblast growth factor 10
8823 FGF16; fibroblast growth factor 16
2250 FGF5; fibroblast growth factor 5
8817 FGF18; fibroblast growth factor 18
26281 FGF20; fibroblast growth factor 20
27006 FGF22; fibroblast growth factor 22
9965 FGF19; fibroblast growth factor 19
26291 FGF21; fibroblast growth factor 21
8074 FGF23; fibroblast growth factor 23
5154 PDGFA; platelet derived growth factor subunit A
5155 PDGFB; platelet derived growth factor subunit B
56034 PDGFC; platelet derived growth factor C
80310 PDGFD; platelet derived growth factor D
3645 INSRR; insulin receptor related receptor
1956 EGFR; epidermal growth factor receptor
2260 FGFR1; fibroblast growth factor receptor 1
2263 FGFR2; fibroblast growth factor receptor 2
2261 FGFR3; fibroblast growth factor receptor 3
2264 FGFR4; fibroblast growth factor receptor 4
5156 PDGFRA; platelet derived growth factor receptor alpha
5159 PDGFRB; platelet derived growth factor receptor beta
2335 FN1; fibronectin 1
3672 ITGA1; integrin subunit alpha 1
3673 ITGA2; integrin subunit alpha 2
3674 ITGA2B; integrin subunit alpha 2b
3675 ITGA3; integrin subunit alpha 3
3676 ITGA4; integrin subunit alpha 4
3678 ITGA5; integrin subunit alpha 5
3655 ITGA6; integrin subunit alpha 6
3679 ITGA7; integrin subunit alpha 7
8516 ITGA8; integrin subunit alpha 8
3680 ITGA9; integrin subunit alpha 9
8515 ITGA10; integrin subunit alpha 10
22801 ITGA11; integrin subunit alpha 11
3685 ITGAV; integrin subunit alpha V
3683 ITGAL; integrin subunit alpha L
3684 ITGAM; integrin subunit alpha M
3687 ITGAX; integrin subunit alpha X
3681 ITGAD; integrin subunit alpha D
3682 ITGAE; integrin subunit alpha E
3688 ITGB1; integrin subunit beta 1
3689 ITGB2; integrin subunit beta 2
3690 ITGB3; integrin subunit beta 3
3691 ITGB4; integrin subunit beta 4
3693 ITGB5; integrin subunit beta 5
3694 ITGB6; integrin subunit beta 6
3695 ITGB7; integrin subunit beta 7
3696 ITGB8; integrin subunit beta 8
3827 KNG1; kininogen 1
623 BDKRB1; bradykinin receptor B1
624 BDKRB2; bradykinin receptor B2
1128 CHRM1; cholinergic receptor muscarinic 1
1129 CHRM2; cholinergic receptor muscarinic 2
1131 CHRM3; cholinergic receptor muscarinic 3
1132 CHRM4; cholinergic receptor muscarinic 4
1133 CHRM5; cholinergic receptor muscarinic 5
727 C5; complement C5
729 C6; complement C6
730 C7; complement C7
731 C8A; complement C8 alpha chain
732 C8B; complement C8 beta chain
733 C8G; complement C8 gamma chain
735 C9; complement C9
2768 GNA12; G protein subunit alpha 12
10672 GNA13; G protein subunit alpha 13
55970 GNG12; G protein subunit gamma 12
2245 FGD1; FYVE, RhoGEF and PH domain containing 1
89846 FGD3; FYVE, RhoGEF and PH domain containing 3
5747 PTK2; protein tyrosine kinase 2
9564 BCAR1; BCAR1 scaffold protein, Cas family member
1398 CRK; CRK proto-oncogene, adaptor protein
1399 CRKL; CRK like proto-oncogene, adaptor protein
1793 DOCK1; dedicator of cytokinesis 1
6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
6237 RRAS; RAS related
22800 RRAS2; RAS related 2
22808 MRAS; muscle RAS oncogene homolog
9459 ARHGEF6; Rac/Cdc42 guanine nucleotide exchange factor 6
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
10451 VAV3; vav guanine nucleotide exchange factor 3
7409 VAV1; vav guanine nucleotide exchange factor 1
7410 VAV2; vav guanine nucleotide exchange factor 2
7074 TIAM1; TIAM Rac1 associated GEF 1
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
4342 MOS; MOS proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
28984 RGCC; regulator of cell cycle
9138 ARHGEF1; Rho guanine nucleotide exchange factor 1
23365 ARHGEF12; Rho guanine nucleotide exchange factor 12
2909 ARHGAP35; Rho GTPase activating protein 35
387 RHOA; ras homolog family member A
5879 RAC1; Rac family small GTPase 1
5880 RAC2; Rac family small GTPase 2
5881 RAC3; Rac family small GTPase 3
998 CDC42; cell division cycle 42
5058 PAK1; p21 (RAC1) activated kinase 1
5062 PAK2; p21 (RAC1) activated kinase 2
5063 PAK3; p21 (RAC1) activated kinase 3
10298 PAK4; p21 (RAC1) activated kinase 4
57144 PAK5; p21 (RAC1) activated kinase 5
56924 PAK6; p21 (RAC1) activated kinase 6
106821730 BUB1B-PAK6; BUB1B-PAK6 readthrough
8874 ARHGEF7; Rho guanine nucleotide exchange factor 7
28964 GIT1; GIT ArfGAP 1
6093 ROCK1; Rho associated coiled-coil containing protein kinase 1
9475 ROCK2; Rho associated coiled-coil containing protein kinase 2
4638 MYLK; myosin light chain kinase
85366 MYLK2; myosin light chain kinase 2
91807 MYLK3; myosin light chain kinase 3
340156 MYLK4; myosin light chain kinase family member 4
5499 PPP1CA; protein phosphatase 1 catalytic subunit alpha
5500 PPP1CB; protein phosphatase 1 catalytic subunit beta
5501 PPP1CC; protein phosphatase 1 catalytic subunit gamma
4659 PPP1R12A; protein phosphatase 1 regulatory subunit 12A
4660 PPP1R12B; protein phosphatase 1 regulatory subunit 12B
54776 PPP1R12C; protein phosphatase 1 regulatory subunit 12C
4633 MYL2; myosin light chain 2
4636 MYL5; myosin light chain 5
58498 MYL7; myosin light chain 7
10398 MYL9; myosin light chain 9
93408 MYL10; myosin light chain 10
103910 MYL12B; myosin light chain 12B
10627 MYL12A; myosin light chain 12A
29895 MYL11; myosin light chain 11
4627 MYH9; myosin heavy chain 9
4628 MYH10; myosin heavy chain 10
4629 MYH11; myosin heavy chain 11
79784 MYH14; myosin heavy chain 14
1729 DIAPH1; diaphanous related formin 1
1730 DIAPH2; diaphanous related formin 2
6548 SLC9A1; solute carrier family 9 member A1
23396 PIP5K1C; phosphatidylinositol-4-phosphate 5-kinase type 1 gamma
8394 PIP5K1A; phosphatidylinositol-4-phosphate 5-kinase type 1 alpha
8395 PIP5K1B; phosphatidylinositol-4-phosphate 5-kinase type 1 beta
79837 PIP4K2C; phosphatidylinositol-5-phosphate 4-kinase type 2 gamma
5305 PIP4K2A; phosphatidylinositol-5-phosphate 4-kinase type 2 alpha
8396 PIP4K2B; phosphatidylinositol-5-phosphate 4-kinase type 2 beta
200576 PIKFYVE; phosphoinositide kinase, FYVE-type zinc finger containing
3984 LIMK1; LIM domain kinase 1
3985 LIMK2; LIM domain kinase 2
81624 DIAPH3; diaphanous related formin 3
10458 BAIAP2; BAR/IMD domain containing adaptor protein 2
55740 ENAH; ENAH actin regulator
8976 WASL; WASP like actin nucleation promoting factor
10163 WASF2; WASP family member 2
23191 CYFIP1; cytoplasmic FMR1 interacting protein 1
26999 CYFIP2; cytoplasmic FMR1 interacting protein 2
10787 NCKAP1; NCK associated protein 1
3071 NCKAP1L; NCK associated protein 1 like
10152 ABI2; abl interactor 2
55845 BRK1; BRICK1 subunit of SCAR/WAVE actin nucleating complex
8936 WASF1; WASP family member 1
10097 ACTR2; actin related protein 2
57180 ACTR3B; actin related protein 3B
653857 ACTR3C; actin related protein 3C
10096 ACTR3; actin related protein 3
10095 ARPC1B; actin related protein 2/3 complex subunit 1B
10552 ARPC1A; actin related protein 2/3 complex subunit 1A
10109 ARPC2; actin related protein 2/3 complex subunit 2
10094 ARPC3; actin related protein 2/3 complex subunit 3
10093 ARPC4; actin related protein 2/3 complex subunit 4
10092 ARPC5; actin related protein 2/3 complex subunit 5
81873 ARPC5L; actin related protein 2/3 complex subunit 5 like
71 ACTG1; actin gamma 1
60 ACTB; actin beta
345456 PFN3; profilin 3
5216 PFN1; profilin 1
5217 PFN2; profilin 2
375189 PFN4; profilin family member 4
5829 PXN; paxillin
7430 EZR; ezrin
5962 RDX; radixin
4478 MSN; moesin
7114 TMSB4X; thymosin beta 4 X-linked
9087 TMSB4Y; thymosin beta 4 Y-linked
1072 CFL1; cofilin 1
1073 CFL2; cofilin 2
54434 SSH1; slingshot protein phosphatase 1
54961 SSH3; slingshot protein phosphatase 3
85464 SSH2; slingshot protein phosphatase 2
7414 VCL; vinculin
8826 IQGAP1; IQ motif containing GTPase activating protein 1
10788 IQGAP2; IQ motif containing GTPase activating protein 2
128239 IQGAP3; IQ motif containing GTPase activating protein 3
2934 GSN; gelsolin
85477 SCIN; scinderin
87 ACTN1; actinin alpha 1
81 ACTN4; actinin alpha 4
324 APC; APC regulator of WNT signaling pathway
10297 APC2; APC regulator of WNT signaling pathway 2
50649 ARHGEF4; Rho guanine nucleotide exchange factor 4
221178 SPATA13; spermatogenesis associated 13
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K04289 LPAR1; lysophosphatidic acid receptor 1
K04291 LPAR2; lysophosphatidic acid receptor 2
K04275 LPAR4; lysophosphatidic acid receptor 4
K08390 LPAR5; lysophosphatidic acid receptor 5
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4; C-X-C chemokine receptor type 4
K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
K03914 F2R; coagulation factor II (thrombin) receptor
K04526 INS; insulin
K04357 EGF; epidermal growth factor
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05450 PDGFC_D; platelet derived growth factor C/D
K05086 INSRR; insulin receptor-related receptor [EC:2.7.10.1]
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05717 FN1; fibronectin 1
K06480 ITGA1; integrin alpha 1
K06481 ITGA2; integrin alpha 2
K06476 ITGA2B; integrin alpha 2B
K06482 ITGA3; integrin alpha 3
K06483 ITGA4; integrin alpha 4
K06484 ITGA5; integrin alpha 5
K06485 ITGA6; integrin alpha 6
K06583 ITGA7; integrin alpha 7
K06584 ITGA8; integrin alpha 8
K06585 ITGA9; integrin alpha 9
K06586 ITGA10; integrin alpha 10
K06587 ITGA11; integrin alpha 11
K06487 ITGAV; integrin alpha V
K05718 ITGAL; integrin alpha L
K06461 ITGAM; integrin alpha M
K06462 ITGAX; integrin alpha X
K06594 ITGAD; integrin alpha D
K06524 ITGAE; integrin alpha E
K05719 ITGB1; integrin beta 1
K06464 ITGB2; integrin beta 2
K06493 ITGB3; integrin beta 3
K06525 ITGB4; integrin beta 4
K06588 ITGB5; integrin beta 5
K06589 ITGB6; integrin beta 6
K06590 ITGB7; integrin beta 7
K06591 ITGB8; integrin beta 8
K03898 KNG; kininogen
K03915 BDKRB1; bradykinin receptor B1
K03916 BDKRB2; bradykinin receptor B2
K04129 CHRM1; muscarinic acetylcholine receptor M1
K04130 CHRM2; muscarinic acetylcholine receptor M2
K04131 CHRM3; muscarinic acetylcholine receptor M3
K04132 CHRM4; muscarinic acetylcholine receptor M4
K04133 CHRM5; muscarinic acetylcholine receptor M5
K03994 C5; complement component 5
K03995 C6; complement component 6
K03996 C7; complement component 7
K03997 C8A; complement component 8 subunit alpha
K03998 C8B; complement component 8 subunit beta
K03999 C8G; complement component 8 subunit gamma
K04000 C9; complement component 9
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K05720 FGD1; FYVE, RhoGEF and PH domain containing 1
K05722 FGD3; FYVE, RhoGEF and PH domain containing 3
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K05726 BCAR1; breast cancer anti-estrogen resistance 1
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K13708 DOCK1; dedicator of cytokinesis protein 1
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2; Ras-related protein R-Ras2
K07831 MRAS; Ras-related protein M-Ras
K05729 ARHGEF6; Rho guanine nucleotide exchange factor 6
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K05731 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04367 MOS; proto-oncogene serine/threonine-protein kinase mos [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K26108 RGCC; regulator of cell cycle RGCC
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K07532 ARHGEF12; Rho guanine nucleotide exchange factor 12
K05732 ARHGAP35; glucocorticoid receptor DNA-binding factor 1
K04513 RHOA; Ras homolog gene family, member A
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04393 CDC42; cell division control protein 42
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K13710 ARHGEF7; Rho guanine nucleotide exchange factor 7
K05737 GIT1; G protein-coupled receptor kinase interactor 1
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06270 PPP1R12A; protein phosphatase 1 regulatory subunit 12A
K12329 PPP1R12B; protein phosphatase 1 regulatory subunit 12B
K17457 PPP1R12C; protein phosphatase 1 regulatory subunit 12C
K10351 MYL2; myosin regulatory light chain 2
K12753 MYL5; myosin regulatory light chain 5
K12754 MYL7; myosin regulatory light chain 7
K12755 MYL9; myosin regulatory light chain 9
K12756 MYL10; myosin regulatory light chain 10
K12757 MYL12; myosin regulatory light chain 12
K12757 MYL12; myosin regulatory light chain 12
K12758 MYLPF; fast skeletal myosin light chain 2
K10352 MYH9s; myosin heavy chain 9/10/11/14
K10352 MYH9s; myosin heavy chain 9/10/11/14
K10352 MYH9s; myosin heavy chain 9/10/11/14
K10352 MYH9s; myosin heavy chain 9/10/11/14
K05740 DIAPH1; diaphanous 1
K05741 DIAPH2; diaphanous 2
K05742 SLC9A1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K00920 PIP4K2; 1-phosphatidylinositol-5-phosphate 4-kinase [EC:2.7.1.149]
K00920 PIP4K2; 1-phosphatidylinositol-5-phosphate 4-kinase [EC:2.7.1.149]
K00920 PIP4K2; 1-phosphatidylinositol-5-phosphate 4-kinase [EC:2.7.1.149]
K00921 PIKFYVE; 1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150]
K05743 LIMK1; LIM domain kinase 1 [EC:2.7.11.1]
K05744 LIMK2; LIM domain kinase 2 [EC:2.7.11.1]
K05745 DIAPH3; diaphanous 3
K05627 BAIAP2; BAI1-associated protein 2
K05746 ENAH; enabled
K23612 WASL; neural Wiskott-Aldrich syndrome protein
K05748 WASF2; WAS protein family, member 2
K05749 CYFIP; cytoplasmic FMR1 interacting protein
K05749 CYFIP; cytoplasmic FMR1 interacting protein
K05750 NCKAP1; NCK-associated protein 1
K05750 NCKAP1; NCK-associated protein 1
K05751 ABI2; abl interactor 2
K05752 C3ORF10; chromosome 3 open reading frame 10
K05753 WASF1; WAS protein family, member 1
K17260 ACTR2; actin-related protein 2
K18584 ACTR3; actin-related protein 3
K18584 ACTR3; actin-related protein 3
K18584 ACTR3; actin-related protein 3
K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
K05758 ARPC2; actin related protein 2/3 complex, subunit 2
K05756 ARPC3; actin related protein 2/3 complex, subunit 3
K05755 ARPC4; actin related protein 2/3 complex, subunit 4
K05754 ARPC5; actin related protein 2/3 complex, subunit 5
K05754 ARPC5; actin related protein 2/3 complex, subunit 5
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
K05759 PFN; profilin
K05759 PFN; profilin
K05759 PFN; profilin
K05759 PFN; profilin
K05760 PXN; paxillin
K08007 EZR; ezrin
K05762 RDX; radixin
K05763 MSN; moesin
K05764 TMSB4; thymosin, beta 4
K05764 TMSB4; thymosin, beta 4
K05765 CFL; cofilin
K05765 CFL; cofilin
K05766 SSH; protein phosphatase slingshot [EC:3.1.3.16 3.1.3.48]
K05766 SSH; protein phosphatase slingshot [EC:3.1.3.16 3.1.3.48]
K05766 SSH; protein phosphatase slingshot [EC:3.1.3.16 3.1.3.48]
K05700 VCL; vinculin
K16848 IQGAP1; Ras GTPase-activating-like protein IQGAP1
K05767 IQGAP2_3; Ras GTPase-activating-like protein IQGAP2/3
K05767 IQGAP2_3; Ras GTPase-activating-like protein IQGAP2/3
K05768 GSN; gelsolin
K05768 GSN; gelsolin
K05699 ACTN1_4; actinin alpha 1/4
K05699 ACTN1_4; actinin alpha 1/4
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K05769 ARHGEF4_29; Rho guanine nucleotide exchange factor 4/29
K05769 ARHGEF4_29; Rho guanine nucleotide exchange factor 4/29
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09150 Organismal Systems
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09151 Immune system
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04640 Hematopoietic cell lineage [PATH:hsa04640]
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04610 Complement and coagulation cascades [PATH:hsa04610]
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04611 Platelet activation [PATH:hsa04611]
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04613 Neutrophil extracellular trap formation [PATH:hsa04613]
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04620 Toll-like receptor signaling pathway [PATH:hsa04620]
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04624 Toll and Imd signaling pathway
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04621 NOD-like receptor signaling pathway [PATH:hsa04621]
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04622 RIG-I-like receptor signaling pathway [PATH:hsa04622]
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04623 Cytosolic DNA-sensing pathway [PATH:hsa04623]
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04625 C-type lectin receptor signaling pathway [PATH:hsa04625]
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04650 Natural killer cell mediated cytotoxicity [PATH:hsa04650]
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3105 HLA-A; major histocompatibility complex, class I, A
3106 HLA-B; major histocompatibility complex, class I, B
3107 HLA-C; major histocompatibility complex, class I, C
3134 HLA-F; major histocompatibility complex, class I, F
3135 HLA-G; major histocompatibility complex, class I, G
3133 HLA-E; major histocompatibility complex, class I, E
3812 KIR3DL2; killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2
3811 KIR3DL1; killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1
115653 KIR3DL3; killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3
3803 KIR2DL2; killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2
3802 KIR2DL1; killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1
3804 KIR2DL3; killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3
57292 KIR2DL5A; killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 5A
3821 KLRC1; killer cell lectin like receptor C1
3824 KLRD1; killer cell lectin like receptor D1
5777 PTPN6; protein tyrosine phosphatase non-receptor type 6
5781 PTPN11; protein tyrosine phosphatase non-receptor type 11
3383 ICAM1; intercellular adhesion molecule 1
3384 ICAM2; intercellular adhesion molecule 2
3683 ITGAL; integrin subunit alpha L
3689 ITGB2; integrin subunit beta 2
2185 PTK2B; protein tyrosine kinase 2 beta
10451 VAV3; vav guanine nucleotide exchange factor 3
7409 VAV1; vav guanine nucleotide exchange factor 1
7410 VAV2; vav guanine nucleotide exchange factor 2
5879 RAC1; Rac family small GTPase 1
5880 RAC2; Rac family small GTPase 2
5881 RAC3; Rac family small GTPase 3
5058 PAK1; p21 (RAC1) activated kinase 1
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
7124 TNF; tumor necrosis factor
1437 CSF2; colony stimulating factor 2
3458 IFNG; interferon gamma
3806 KIR2DS1; killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 1
3808 KIR2DS3; killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 3
3809 KIR2DS4; killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4
3810 KIR2DS5; killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 5
100132285 KIR2DS2; killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 2
3822 KLRC2; killer cell lectin like receptor C2
3823 KLRC3; killer cell lectin like receptor C3
9436 NCR2; natural cytotoxicity triggering receptor 2
7305 TYROBP; transmembrane immune signaling adaptor TYROBP
3932 LCK; LCK proto-oncogene, Src family tyrosine kinase
102723407 IGH; immunoglobulin heavy variable 4-38-2-like
2214 FCGR3A; Fc gamma receptor IIIa
2215 FCGR3B; Fc gamma receptor IIIb
9437 NCR1; natural cytotoxicity triggering receptor 1
259197 NCR3; natural cytotoxicity triggering receptor 3
2207 FCER1G; Fc epsilon receptor Ig
919 CD247; CD247 molecule
7535 ZAP70; zeta chain of T cell receptor associated protein kinase 70
6850 SYK; spleen associated tyrosine kinase
3937 LCP2; lymphocyte cytosolic protein 2
27040 LAT; linker for activation of T cells
7462 LAT2; linker for activation of T cells family member 2
5335 PLCG1; phospholipase C gamma 1
5336 PLCG2; phospholipase C gamma 2
6452 SH3BP2; SH3 domain binding protein 2
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
2534 FYN; FYN proto-oncogene, Src family tyrosine kinase
6464 SHC1; SHC adaptor protein 1
25759 SHC2; SHC adaptor protein 2
53358 SHC3; SHC adaptor protein 3
399694 SHC4; SHC adaptor protein 4
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
4277 MICB; MHC class I polypeptide-related sequence B
100507436 MICA; MHC class I polypeptide-related sequence A
80329 ULBP1; UL16 binding protein 1
80328 ULBP2; UL16 binding protein 2
79465 ULBP3; UL16 binding protein 3
22914 KLRK1; killer cell lectin like receptor K1
100528032 KLRC4-KLRK1; KLRC4-KLRK1 readthrough
10870 HCST; hematopoietic cell signal transducer
962 CD48; CD48 molecule
51744 CD244; CD244 molecule
5530 PPP3CA; protein phosphatase 3 catalytic subunit alpha
5532 PPP3CB; protein phosphatase 3 catalytic subunit beta
5533 PPP3CC; protein phosphatase 3 catalytic subunit gamma
5534 PPP3R1; protein phosphatase 3 regulatory subunit B, alpha
5535 PPP3R2; protein phosphatase 3 regulatory subunit B, beta
4772 NFATC1; nuclear factor of activated T cells 1
4773 NFATC2; nuclear factor of activated T cells 2
5578 PRKCA; protein kinase C alpha
5579 PRKCB; protein kinase C beta
5582 PRKCG; protein kinase C gamma
117157 SH2D1B; SH2 domain containing 1B
4068 SH2D1A; SH2 domain containing 1A
3459 IFNGR1; interferon gamma receptor 1
3460 IFNGR2; interferon gamma receptor 2
3439 IFNA1; interferon alpha 1
3440 IFNA2; interferon alpha 2
3441 IFNA4; interferon alpha 4
3442 IFNA5; interferon alpha 5
3443 IFNA6; interferon alpha 6
3444 IFNA7; interferon alpha 7
3445 IFNA8; interferon alpha 8
3446 IFNA10; interferon alpha 10
3447 IFNA13; interferon alpha 13
3448 IFNA14; interferon alpha 14
3449 IFNA16; interferon alpha 16
3451 IFNA17; interferon alpha 17
3452 IFNA21; interferon alpha 21
3456 IFNB1; interferon beta 1
3454 IFNAR1; interferon alpha and beta receptor subunit 1
3455 IFNAR2; interferon alpha and beta receptor subunit 2
8743 TNFSF10; TNF superfamily member 10
8797 TNFRSF10A; TNF receptor superfamily member 10a
8795 TNFRSF10B; TNF receptor superfamily member 10b
356 FASLG; Fas ligand
355 FAS; Fas cell surface death receptor
3002 GZMB; granzyme B
5551 PRF1; perforin 1
836 CASP3; caspase 3
637 BID; BH3 interacting domain death agonist
353091 RAET1G; retinoic acid early transcript 1G
154064 RAET1L; retinoic acid early transcript 1L
135250 RAET1E; retinoic acid early transcript 1E
|
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K07980 KIR3DL; killer cell immunoglobulin-like receptor 3DL
K07980 KIR3DL; killer cell immunoglobulin-like receptor 3DL
K07980 KIR3DL; killer cell immunoglobulin-like receptor 3DL
K07981 KIR2DL1_2_3; killer cell immunoglobulin-like receptor 2DL1/2/3
K07981 KIR2DL1_2_3; killer cell immunoglobulin-like receptor 2DL1/2/3
K07981 KIR2DL1_2_3; killer cell immunoglobulin-like receptor 2DL1/2/3
K24232 KIR2DL5; killer cell immunoglobulin-like receptor 2DL5
K06541 KLRC1; killer cell lectin-like receptor subfamily C1
K06516 KLRD1; killer cell lectin-like receptor subfamily D member 1
K05697 PTPN6; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K06490 ICAM1; intercellular adhesion molecule 1
K06523 ICAM2; intercellular adhesion molecule 2
K05718 ITGAL; integrin alpha L
K06464 ITGB2; integrin beta 2
K05871 PTK2B; focal adhesion kinase 2 [EC:2.7.10.2]
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K03156 TNF; tumor necrosis factor superfamily, member 2
K05427 CSF2; granulocyte-macrophage colony-stimulating factor
K04687 IFNG; interferon gamma
K07982 KIR2DS; killer cell immunoglobulin-like receptor 2DS
K07982 KIR2DS; killer cell immunoglobulin-like receptor 2DS
K07982 KIR2DS; killer cell immunoglobulin-like receptor 2DS
K07982 KIR2DS; killer cell immunoglobulin-like receptor 2DS
K07982 KIR2DS; killer cell immunoglobulin-like receptor 2DS
K24233 KLRC2_3; killer cell lectin-like receptor subfamily C2/3
K24233 KLRC2_3; killer cell lectin-like receptor subfamily C2/3
K06742 NCR2; natural cytotoxicity triggering receptor 2
K07992 TYROBP; TYRO protein tyrosine kinase binding protein
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K06856 IGH; immunoglobulin heavy chain
K06463 FCGR3; low affinity immunoglobulin gamma Fc receptor III
K06463 FCGR3; low affinity immunoglobulin gamma Fc receptor III
K06741 NCR1; natural cytotoxicity triggering receptor 1
K06743 NCR3; natural cytotoxicity triggering receptor 3
K07983 FCER1G; high affinity immunoglobulin epsilon receptor subunit gamma
K06453 CD3Z; CD3Z antigen, zeta polypeptide
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K07361 LCP2; lymphocyte cytosolic protein 2
K07362 LAT; linker for activation of T cells family member 1
K26356 LAT2; linker for activation of T-cells family member 2
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K07984 SH3BP2; SH3-domain binding protein 2
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K07985 MIC; MHC class I-related protein
K07985 MIC; MHC class I-related protein
K07986 ULBP; UL16 binding protein
K07986 ULBP; UL16 binding protein
K07986 ULBP; UL16 binding protein
K06728 KLRK1; killer cell lectin-like receptor subfamily K member 1
K06728 KLRK1; killer cell lectin-like receptor subfamily K member 1
K07988 HCST; hematopoietic cell signal transducer
K06479 CD48; CD48 antigen
K06582 CD244; natural killer cell receptor 2B4
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K07989 SH2D1B; SH2 domain-containing protein 1B
K07990 SH2D1A; SH2 domain-containing protein 1A
K05132 IFNGR1; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K04721 TNFSF10; tumor necrosis factor ligand superfamily member 10
K04722 TNFRSF10A_B; tumor necrosis factor receptor superfamily member 10A/B
K04722 TNFRSF10A_B; tumor necrosis factor receptor superfamily member 10A/B
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K01353 GZMB; granzyme B [EC:3.4.21.79]
K07818 PRF1; perforin 1
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04726 BID; BH3 interacting domain death agonist
K07987 RAET1; retinoic acid early transcript 1
K07987 RAET1; retinoic acid early transcript 1
K07987 RAET1; retinoic acid early transcript 1
|
04612 Antigen processing and presentation [PATH:hsa04612]
|
04660 T cell receptor signaling pathway [PATH:hsa04660]
|
04658 Th1 and Th2 cell differentiation [PATH:hsa04658]
|
04659 Th17 cell differentiation [PATH:hsa04659]
|
04657 IL-17 signaling pathway [PATH:hsa04657]
|
04662 B cell receptor signaling pathway [PATH:hsa04662]
|
04664 Fc epsilon RI signaling pathway [PATH:hsa04664]
|
04666 Fc gamma R-mediated phagocytosis [PATH:hsa04666]
|
04670 Leukocyte transendothelial migration [PATH:hsa04670]
|
04672 Intestinal immune network for IgA production [PATH:hsa04672]
|
04062 Chemokine signaling pathway [PATH:hsa04062]
|
2919 CXCL1; C-X-C motif chemokine ligand 1
2920 CXCL2; C-X-C motif chemokine ligand 2
2921 CXCL3; C-X-C motif chemokine ligand 3
6374 CXCL5; C-X-C motif chemokine ligand 5
6372 CXCL6; C-X-C motif chemokine ligand 6
5473 PPBP; pro-platelet basic protein
3576 CXCL8; C-X-C motif chemokine ligand 8
4283 CXCL9; C-X-C motif chemokine ligand 9
3627 CXCL10; C-X-C motif chemokine ligand 10
6373 CXCL11; C-X-C motif chemokine ligand 11
6387 CXCL12; C-X-C motif chemokine ligand 12
10563 CXCL13; C-X-C motif chemokine ligand 13
58191 CXCL16; C-X-C motif chemokine ligand 16
5196 PF4; platelet factor 4
5197 PF4V1; platelet factor 4 variant 1
9547 CXCL14; C-X-C motif chemokine ligand 14
6375 XCL1; X-C motif chemokine ligand 1
6846 XCL2; X-C motif chemokine ligand 2
6376 CX3CL1; C-X3-C motif chemokine ligand 1
6346 CCL1; C-C motif chemokine ligand 1
6347 CCL2; C-C motif chemokine ligand 2
6348 CCL3; C-C motif chemokine ligand 3
6349 CCL3L1; C-C motif chemokine ligand 3 like 1
414062 CCL3L3; C-C motif chemokine ligand 3 like 3
6351 CCL4; C-C motif chemokine ligand 4
9560 CCL4L2; C-C motif chemokine ligand 4 like 2
388372 CCL4L1; C-C motif chemokine ligand 4 like 1
6352 CCL5; C-C motif chemokine ligand 5
6354 CCL7; C-C motif chemokine ligand 7
6355 CCL8; C-C motif chemokine ligand 8
6356 CCL11; C-C motif chemokine ligand 11
6357 CCL13; C-C motif chemokine ligand 13
6358 CCL14; C-C motif chemokine ligand 14
6359 CCL15; C-C motif chemokine ligand 15
6368 CCL23; C-C motif chemokine ligand 23
6360 CCL16; C-C motif chemokine ligand 16
6361 CCL17; C-C motif chemokine ligand 17
6362 CCL18; C-C motif chemokine ligand 18
6363 CCL19; C-C motif chemokine ligand 19
6364 CCL20; C-C motif chemokine ligand 20
6366 CCL21; C-C motif chemokine ligand 21
6367 CCL22; C-C motif chemokine ligand 22
6369 CCL24; C-C motif chemokine ligand 24
6370 CCL25; C-C motif chemokine ligand 25
10344 CCL26; C-C motif chemokine ligand 26
10850 CCL27; C-C motif chemokine ligand 27
56477 CCL28; C-C motif chemokine ligand 28
3579 CXCR2; C-X-C motif chemokine receptor 2
3577 CXCR1; C-X-C motif chemokine receptor 1
2833 CXCR3; C-X-C motif chemokine receptor 3
7852 CXCR4; C-X-C motif chemokine receptor 4
643 CXCR5; C-X-C motif chemokine receptor 5
10663 CXCR6; C-X-C motif chemokine receptor 6
2829 XCR1; X-C motif chemokine receptor 1
1524 CX3CR1; C-X3-C motif chemokine receptor 1
1237 CCR8; C-C motif chemokine receptor 8
1235 CCR6; C-C motif chemokine receptor 6
10803 CCR9; C-C motif chemokine receptor 9
1233 CCR4; C-C motif chemokine receptor 4
1236 CCR7; C-C motif chemokine receptor 7
729230 CCR2; C-C motif chemokine receptor 2
1234 CCR5; C-C motif chemokine receptor 5
1230 CCR1; C-C motif chemokine receptor 1
1232 CCR3; C-C motif chemokine receptor 3
2826 CCR10; C-C motif chemokine receptor 10
3717 JAK2; Janus kinase 2
3718 JAK3; Janus kinase 3
6772 STAT1; signal transducer and activator of transcription 1
6773 STAT2; signal transducer and activator of transcription 2
6774 STAT3; signal transducer and activator of transcription 3
6777 STAT5B; signal transducer and activator of transcription 5B
2770 GNAI1; G protein subunit alpha i1
2773 GNAI3; G protein subunit alpha i3
2771 GNAI2; G protein subunit alpha i2
107 ADCY1; adenylate cyclase 1
108 ADCY2; adenylate cyclase 2
109 ADCY3; adenylate cyclase 3
196883 ADCY4; adenylate cyclase 4
111 ADCY5; adenylate cyclase 5
112 ADCY6; adenylate cyclase 6
113 ADCY7; adenylate cyclase 7
114 ADCY8; adenylate cyclase 8
115 ADCY9; adenylate cyclase 9
5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
4067 LYN; LYN proto-oncogene, Src family tyrosine kinase
3055 HCK; HCK proto-oncogene, Src family tyrosine kinase
2268 FGR; FGR proto-oncogene, Src family tyrosine kinase
6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase
6464 SHC1; SHC adaptor protein 1
25759 SHC2; SHC adaptor protein 2
53358 SHC3; SHC adaptor protein 3
399694 SHC4; SHC adaptor protein 4
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
5294 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
23533 PIK3R5; phosphoinositide-3-kinase regulatory subunit 5
146850 PIK3R6; phosphoinositide-3-kinase regulatory subunit 6
5590 PRKCZ; protein kinase C zeta
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
2309 FOXO3; forkhead box O3
1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
4792 NFKBIA; NFKB inhibitor alpha
4793 NFKBIB; NFKB inhibitor beta
4790 NFKB1; nuclear factor kappa B subunit 1
5970 RELA; RELA proto-oncogene, NF-kB subunit
572 BAD; BCL2 associated agonist of cell death
2931 GSK3A; glycogen synthase kinase 3 alpha
2932 GSK3B; glycogen synthase kinase 3 beta
3702 ITK; IL2 inducible T cell kinase
10451 VAV3; vav guanine nucleotide exchange factor 3
7409 VAV1; vav guanine nucleotide exchange factor 1
7410 VAV2; vav guanine nucleotide exchange factor 2
5879 RAC1; Rac family small GTPase 1
5880 RAC2; Rac family small GTPase 2
5881 RAC3; Rac family small GTPase 3
5058 PAK1; p21 (RAC1) activated kinase 1
998 CDC42; cell division cycle 42
7454 WAS; WASP actin nucleation promoting factor
387 RHOA; ras homolog family member A
6093 ROCK1; Rho associated coiled-coil containing protein kinase 1
9475 ROCK2; Rho associated coiled-coil containing protein kinase 2
2782 GNB1; G protein subunit beta 1
2783 GNB2; G protein subunit beta 2
2784 GNB3; G protein subunit beta 3
59345 GNB4; G protein subunit beta 4
10681 GNB5; G protein subunit beta 5
54331 GNG2; G protein subunit gamma 2
2785 GNG3; G protein subunit gamma 3
2786 GNG4; G protein subunit gamma 4
2787 GNG5; G protein subunit gamma 5
2788 GNG7; G protein subunit gamma 7
94235 GNG8; G protein subunit gamma 8
2790 GNG10; G protein subunit gamma 10
2791 GNG11; G protein subunit gamma 11
55970 GNG12; G protein subunit gamma 12
51764 GNG13; G protein subunit gamma 13
2792 GNGT1; G protein subunit gamma transducin 1
2793 GNGT2; G protein subunit gamma transducin 2
57580 PREX1; phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1
9844 ELMO1; engulfment and cell motility 1
1794 DOCK2; dedicator of cytokinesis 2
5747 PTK2; protein tyrosine kinase 2
5829 PXN; paxillin
9564 BCAR1; BCAR1 scaffold protein, Cas family member
1398 CRK; CRK proto-oncogene, adaptor protein
1399 CRKL; CRK like proto-oncogene, adaptor protein
2185 PTK2B; protein tyrosine kinase 2 beta
2776 GNAQ; G protein subunit alpha q
23236 PLCB1; phospholipase C beta 1
5330 PLCB2; phospholipase C beta 2
5331 PLCB3; phospholipase C beta 3
5332 PLCB4; phospholipase C beta 4
5335 PLCG1; phospholipase C gamma 1
5336 PLCG2; phospholipase C gamma 2
10235 RASGRP2; RAS guanyl releasing protein 2
5906 RAP1A; RAP1A, member of RAS oncogene family
5908 RAP1B; RAP1B, member of RAS oncogene family
56288 PARD3; par-3 family cell polarity regulator
7074 TIAM1; TIAM Rac1 associated GEF 1
5579 PRKCB; protein kinase C beta
5580 PRKCD; protein kinase C delta
653361 NCF1; neutrophil cytosolic factor 1
131890 GRK7; G protein-coupled receptor kinase 7
6011 GRK1; G protein-coupled receptor kinase 1
156 GRK2; G protein-coupled receptor kinase 2
157 GRK3; G protein-coupled receptor kinase 3
2868 GRK4; G protein-coupled receptor kinase 4
2869 GRK5; G protein-coupled receptor kinase 5
2870 GRK6; G protein-coupled receptor kinase 6
408 ARRB1; arrestin beta 1
409 ARRB2; arrestin beta 2
|
K05505 CXCL1_2_3; C-X-C motif chemokine 1/2/3
K05505 CXCL1_2_3; C-X-C motif chemokine 1/2/3
K05505 CXCL1_2_3; C-X-C motif chemokine 1/2/3
K05506 CXCL5_6; C-X-C motif chemokine 5/6
K05506 CXCL5_6; C-X-C motif chemokine 5/6
K10029 PPBP; platelet basic protein
K10030 IL8; interleukin 8
K05416 CXCL9; C-X-C motif chemokine 9
K12671 CXCL10; C-X-C motif chemokine 10
K12672 CXCL11; C-X-C motif chemokine 11
K10031 CXCL12; C-X-C motif chemokine 12
K10032 CXCL13; C-X-C motif chemokine 13
K10035 CXCL16; C-X-C motif chemokine 16
K05407 PF4; platelet factor 4
K05407 PF4; platelet factor 4
K10033 CXCL14; C-X-C motif chemokine 14
K05507 XCL1; C motif chemokine 1
K22675 XCL2; C motif chemokine 2
K05508 CX3CL1; C-X3-C motif chemokine 1
K05514 CCL1; C-C motif chemokine 1
K14624 CCL2; C-C motif chemokine 2
K05408 CCL3; C-C motif chemokine 3
K05408 CCL3; C-C motif chemokine 3
K05408 CCL3; C-C motif chemokine 3
K12964 CCL4; C-C motif chemokine 4
K12964 CCL4; C-C motif chemokine 4
K12964 CCL4; C-C motif chemokine 4
K12499 CCL5; C-C motif chemokine 5
K05509 CCL7; C-C motif chemokine 7
K16596 CCL8; C-C motif chemokine 8
K16597 CCL11; C-C motif chemokine 11
K16595 CCL13; C-C motif chemokine 13
K21092 CCL14; C-C motif chemokine 14
K05511 CCL15_23; C-C motif chemokine 15/23
K05511 CCL15_23; C-C motif chemokine 15/23
K21093 CCL16; C-C motif chemokine 16
K21083 CCL17; C-C motif chemokine 17
K21094 CCL18; C-C motif chemokine 18
K05512 CCL19; C-C motif chemokine 19
K14625 CCL20; C-C motif chemokine 20
K16062 CCL21; C-C motif chemokine 21
K21095 CCL22; C-C motif chemokine 22
K21097 CCL24; C-C motif chemokine 24
K13072 CCL25; C-C motif chemokine 25
K21096 CCL26; C-C motif chemokine 26
K16598 CCL27; C-C motif chemokine 27
K05513 CCL28; C-C motif chemokine 28
K05050 CXCR2; C-X-C chemokine receptor type 2
K04175 CXCR1; C-X-C chemokine receptor type 1
K04188 CXCR3; C-X-C chemokine receptor type 3
K04189 CXCR4; C-X-C chemokine receptor type 4
K04190 CXCR5; C-X-C chemokine receptor type 5
K04191 CXCR6; C-X-C chemokine receptor type 6
K04193 XCR1; XC chemokine receptor 1
K04192 CX3CR1; CX3C chemokine receptor 1
K04183 CCR8; C-C chemokine receptor type 8
K04181 CCR6; C-C chemokine receptor type 6
K04184 CCR9; C-C chemokine receptor type 9
K04179 CCR4; C-C chemokine receptor type 4
K04182 CCR7; C-C chemokine receptor type 7
K04177 CCR2; C-C chemokine receptor type 2
K04180 CCR5; C-C chemokine receptor type 5
K04176 CCR1; C-C chemokine receptor type 1
K04178 CCR3; C-C chemokine receptor type 3
K04185 CCR10; C-C chemokine receptor type 10
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04692 STAT3; signal transducer and activator of transcription 3
K11224 STAT5B; signal transducer and activator of transcription 5B
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05854 LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
K08893 HCK; hemopoietic cell kinase [EC:2.7.10.2]
K08891 FGR; tyrosine-protein kinase Fgr [EC:2.7.10.2]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K21289 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K09408 FOXO3; forkhead box protein O3
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02581 NFKBIB; NF-kappa-B inhibitor beta
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K02158 BAD; Bcl-2-antagonist of cell death
K08822 GSK3A; glycogen synthase kinase 3 alpha [EC:2.7.11.26]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K07363 ITK; IL2-inducible T-cell kinase [EC:2.7.10.2]
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04393 CDC42; cell division control protein 42
K05747 WAS; Wiskott-Aldrich syndrome protein
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K12365 PREX1; phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchanger 1 protein
K12366 ELMO1; engulfment and cell motility protein 1
K12367 DOCK2; dedicator of cytokinesis protein 2
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K05760 PXN; paxillin
K05726 BCAR1; breast cancer anti-estrogen resistance 1
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K05871 PTK2B; focal adhesion kinase 2 [EC:2.7.10.2]
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K12361 RASGRP2; RAS guanyl-releasing protein 2
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K04237 PARD3; partitioning defective protein 3
K05731 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K08011 NCF1; neutrophil cytosolic factor 1
K00909 GRK1_7; rhodopsin kinase [EC:2.7.11.14]
K00909 GRK1_7; rhodopsin kinase [EC:2.7.11.14]
K00910 ADRBK; beta-adrenergic-receptor kinase [EC:2.7.11.15]
K00910 ADRBK; beta-adrenergic-receptor kinase [EC:2.7.11.15]
K08291 GRK4_5_6; G protein-coupled receptor kinase [EC:2.7.11.16]
K08291 GRK4_5_6; G protein-coupled receptor kinase [EC:2.7.11.16]
K08291 GRK4_5_6; G protein-coupled receptor kinase [EC:2.7.11.16]
K04439 ARRB; beta-arrestin
K04439 ARRB; beta-arrestin
|
|
|
09152 Endocrine system
|
04911 Insulin secretion [PATH:hsa04911]
|
04910 Insulin signaling pathway [PATH:hsa04910]
|
3630 INS; insulin
3643 INSR; insulin receptor
3667 IRS1; insulin receptor substrate 1
8660 IRS2; insulin receptor substrate 2
8471 IRS4; insulin receptor substrate 4
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5170 PDPK1; 3-phosphoinositide dependent protein kinase 1
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
2932 GSK3B; glycogen synthase kinase 3 beta
2998 GYS2; glycogen synthase 2
2997 GYS1; glycogen synthase 1
5499 PPP1CA; protein phosphatase 1 catalytic subunit alpha
5500 PPP1CB; protein phosphatase 1 catalytic subunit beta
5501 PPP1CC; protein phosphatase 1 catalytic subunit gamma
5506 PPP1R3A; protein phosphatase 1 regulatory subunit 3A
5507 PPP1R3C; protein phosphatase 1 regulatory subunit 3C
5509 PPP1R3D; protein phosphatase 1 regulatory subunit 3D
79660 PPP1R3B; protein phosphatase 1 regulatory subunit 3B
90673 PPP1R3E; protein phosphatase 1 regulatory subunit 3E
89801 PPP1R3F; protein phosphatase 1 regulatory subunit 3F
5260 PHKG1; phosphorylase kinase catalytic subunit gamma 1
5261 PHKG2; phosphorylase kinase catalytic subunit gamma 2
5257 PHKB; phosphorylase kinase regulatory subunit beta
5256 PHKA2; phosphorylase kinase regulatory subunit alpha 2
5255 PHKA1; phosphorylase kinase regulatory subunit alpha 1
810 CALML3; calmodulin like 3
805 CALM2; calmodulin 2
808 CALM3; calmodulin 3
801 CALM1; calmodulin 1
163688 CALML6; calmodulin like 6
51806 CALML5; calmodulin like 5
91860 CALML4; calmodulin like 4
5836 PYGL; glycogen phosphorylase L
5837 PYGM; glycogen phosphorylase, muscle associated
5834 PYGB; glycogen phosphorylase B
5140 PDE3B; phosphodiesterase 3B
5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
5573 PRKAR1A; protein kinase cAMP-dependent type I regulatory subunit alpha
5576 PRKAR2A; protein kinase cAMP-dependent type II regulatory subunit alpha
5577 PRKAR2B; protein kinase cAMP-dependent type II regulatory subunit beta
5575 PRKAR1B; protein kinase cAMP-dependent type I regulatory subunit beta
3991 LIPE; lipase E, hormone sensitive type
5590 PRKCZ; protein kinase C zeta
5584 PRKCI; protein kinase C iota
6517 SLC2A4; solute carrier family 2 member 4
2319 FLOT2; flotillin 2
10211 FLOT1; flotillin 1
10603 SH2B2; SH2B adaptor protein 2
10580 SORBS1; sorbin and SH3 domain containing 1
867 CBL; Cbl proto-oncogene
868 CBLB; Cbl proto-oncogene B
1398 CRK; CRK proto-oncogene, adaptor protein
1399 CRKL; CRK like proto-oncogene, adaptor protein
2889 RAPGEF1; Rap guanine nucleotide exchange factor 1
23433 RHOQ; ras homolog family member Q
23265 EXOC7; exocyst complex component 7
9322 TRIP10; thyroid hormone receptor interactor 10
6720 SREBF1; sterol regulatory element binding transcription factor 1
31 ACACA; acetyl-CoA carboxylase alpha
32 ACACB; acetyl-CoA carboxylase beta
2194 FASN; fatty acid synthase
5313 PKLR; pyruvate kinase L/R
3101 HK3; hexokinase 3
3098 HK1; hexokinase 1
3099 HK2; hexokinase 2
80201 HKDC1; hexokinase domain containing 1
2645 GCK; glucokinase
5562 PRKAA1; protein kinase AMP-activated catalytic subunit alpha 1
5563 PRKAA2; protein kinase AMP-activated catalytic subunit alpha 2
5564 PRKAB1; protein kinase AMP-activated non-catalytic subunit beta 1
5565 PRKAB2; protein kinase AMP-activated non-catalytic subunit beta 2
5571 PRKAG1; protein kinase AMP-activated non-catalytic subunit gamma 1
53632 PRKAG3; protein kinase AMP-activated non-catalytic subunit gamma 3
51422 PRKAG2; protein kinase AMP-activated non-catalytic subunit gamma 2
2308 FOXO1; forkhead box O1
10891 PPARGC1A; PPARG coactivator 1 alpha
2538 G6PC1; glucose-6-phosphatase catalytic subunit 1
57818 G6PC2; glucose-6-phosphatase catalytic subunit 2
92579 G6PC3; glucose-6-phosphatase catalytic subunit 3
2203 FBP1; fructose-bisphosphatase 1
8789 FBP2; fructose-bisphosphatase 2
5105 PCK1; phosphoenolpyruvate carboxykinase 1
5106 PCK2; phosphoenolpyruvate carboxykinase 2, mitochondrial
2475 MTOR; mechanistic target of rapamycin kinase
57521 RPTOR; regulatory associated protein of MTOR complex 1
6198 RPS6KB1; ribosomal protein S6 kinase B1
6199 RPS6KB2; ribosomal protein S6 kinase B2
6194 RPS6; ribosomal protein S6
1978 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
1977 EIF4E; eukaryotic translation initiation factor 4E
9470 EIF4E2; eukaryotic translation initiation factor 4E family member 2
253314 EIF4E1B; eukaryotic translation initiation factor 4E family member 1B
7248 TSC1; TSC complex subunit 1
7249 TSC2; TSC complex subunit 2
6009 RHEB; Ras homolog, mTORC1 binding
572 BAD; BCL2 associated agonist of cell death
6464 SHC1; SHC adaptor protein 1
25759 SHC2; SHC adaptor protein 2
53358 SHC3; SHC adaptor protein 3
399694 SHC4; SHC adaptor protein 4
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
8569 MKNK1; MAPK interacting serine/threonine kinase 1
2872 MKNK2; MAPK interacting serine/threonine kinase 2
2002 ELK1; ETS transcription factor ELK1
8651 SOCS1; suppressor of cytokine signaling 1
8835 SOCS2; suppressor of cytokine signaling 2
9021 SOCS3; suppressor of cytokine signaling 3
122809 SOCS4; suppressor of cytokine signaling 4
5770 PTPN1; protein tyrosine phosphatase non-receptor type 1
5792 PTPRF; protein tyrosine phosphatase receptor type F
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
3636 INPPL1; inositol polyphosphate phosphatase like 1
3632 INPP5A; inositol polyphosphate-5-phosphatase A
|
K04526 INS; insulin
K04527 INSR; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K17446 IRS4; insulin receptor substrate 4
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K17453 PPP1R3F; protein phosphatase 1 regulatory subunit 3F
K00871 PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]
K00871 PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]
K07190 PHKA_B; phosphorylase kinase alpha/beta subunit
K07190 PHKA_B; phosphorylase kinase alpha/beta subunit
K07190 PHKA_B; phosphorylase kinase alpha/beta subunit
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
K13296 PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:3.1.4.17]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04739 PRKAR; cAMP-dependent protein kinase regulator
K04739 PRKAR; cAMP-dependent protein kinase regulator
K04739 PRKAR; cAMP-dependent protein kinase regulator
K04739 PRKAR; cAMP-dependent protein kinase regulator
K07188 LIPE; hormone-sensitive lipase [EC:3.1.1.79]
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K06069 PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]
K07191 SLC2A4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
K07192 FLOT; flotillin
K07192 FLOT; flotillin
K07193 SH2B; SH2B adapter protein 2
K06086 SORBS1; sorbin and SH3 domain containing protein 1
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K06277 RAPGEF1; Rap guanine nucleotide exchange factor 1
K07194 RHOQ; Ras homolog gene family, member Q
K07195 EXOC7; exocyst complex component 7
K07196 TRIP10; thyroid hormone receptor interactor 10
K07197 SREBP1; sterol regulatory element-binding transcription factor 1
K11262 ACACA; acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K01946 ACACB; acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K00665 FASN; fatty acid synthase, animal type [EC:2.3.1.85]
K12406 PKLR; pyruvate kinase isozymes R/L [EC:2.7.1.40]
K00844 HK; hexokinase [EC:2.7.1.1]
K00844 HK; hexokinase [EC:2.7.1.1]
K00844 HK; hexokinase [EC:2.7.1.1]
K00844 HK; hexokinase [EC:2.7.1.1]
K12407 GCK; glucokinase [EC:2.7.1.2]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07201 FOXO1; forkhead box protein O1
K07202 PPARGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07204 RAPTOR; regulatory associated protein of mTOR
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02991 RP-S6e; small subunit ribosomal protein S6e
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K03259 EIF4E; translation initiation factor 4E
K03259 EIF4E; translation initiation factor 4E
K03259 EIF4E; translation initiation factor 4E
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K02158 BAD; Bcl-2-antagonist of cell death
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04372 MKNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
K04372 MKNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
K04375 ELK1; ETS domain-containing protein Elk-1
K04694 SOCS1; suppressor of cytokine signaling 1
K04695 SOCS2; suppressor of cytokine signaling 2
K04696 SOCS3; suppressor of cytokine signaling 3
K04697 SOCS4; suppressor of cytokine signaling 4
K05696 PTPN1; tyrosine-protein phosphatase non-receptor type 1 [EC:3.1.3.48]
K05695 PTPRF; receptor-type tyrosine-protein phosphatase F [EC:3.1.3.48]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K15909 SHIP2; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 [EC:3.1.3.86]
K01106 INPP5A; inositol polyphosphate 5-phosphatase INPP5A [EC:3.1.3.56]
|
04922 Glucagon signaling pathway [PATH:hsa04922]
|
04923 Regulation of lipolysis in adipocytes [PATH:hsa04923]
|
04920 Adipocytokine signaling pathway [PATH:hsa04920]
|
03320 PPAR signaling pathway [PATH:hsa03320]
|
04929 GnRH secretion [PATH:hsa04929]
|
04912 GnRH signaling pathway [PATH:hsa04912]
|
04913 Ovarian steroidogenesis [PATH:hsa04913]
|
04915 Estrogen signaling pathway [PATH:hsa04915]
|
04914 Progesterone-mediated oocyte maturation [PATH:hsa04914]
|
5241 PGR; progesterone receptor
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
5600 MAPK11; mitogen-activated protein kinase 11
6300 MAPK12; mitogen-activated protein kinase 12
5603 MAPK13; mitogen-activated protein kinase 13
1432 MAPK14; mitogen-activated protein kinase 14
2770 GNAI1; G protein subunit alpha i1
2773 GNAI3; G protein subunit alpha i3
2771 GNAI2; G protein subunit alpha i2
107 ADCY1; adenylate cyclase 1
108 ADCY2; adenylate cyclase 2
109 ADCY3; adenylate cyclase 3
196883 ADCY4; adenylate cyclase 4
111 ADCY5; adenylate cyclase 5
112 ADCY6; adenylate cyclase 6
113 ADCY7; adenylate cyclase 7
114 ADCY8; adenylate cyclase 8
115 ADCY9; adenylate cyclase 9
5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
6790 AURKA; aurora kinase A
64506 CPEB1; cytoplasmic polyadenylation element binding protein 1
132864 CPEB2; cytoplasmic polyadenylation element binding protein 2
22849 CPEB3; cytoplasmic polyadenylation element binding protein 3
80315 CPEB4; cytoplasmic polyadenylation element binding protein 4
245711 SPDYA; speedy/RINGO cell cycle regulator family member A
387778 SPDYC; speedy/RINGO cell cycle regulator family member C
100310812 SPDYE2B; speedy/RINGO cell cycle regulator family member E2B
100505767 SPDYE18; speedy/RINGO cell cycle regulator family member E18
100996746 SPDYE11; speedy/RINGO cell cycle regulator family member E11
102723555 SPDYE16; speedy/RINGO cell cycle regulator family member E16
102723849 SPDYE17; speedy/RINGO cell cycle regulator family member E17
285955 SPDYE1; speedy/RINGO cell cycle regulator family member E1
388333 SPDYE4; speedy/RINGO cell cycle regulator family member E4
441272 SPDYE3; speedy/RINGO cell cycle regulator family member E3
441273 SPDYE2; speedy/RINGO cell cycle regulator family member E2
442590 SPDYE5; speedy/RINGO cell cycle regulator family member E5
729597 SPDYE6; speedy/RINGO cell cycle regulator family member E6
105180391 SPDYE15; speedy/RINGO cell cycle regulator family member E15
100101268 SPDYE12; speedy/RINGO cell cycle regulator family member E12
124906603 putative speedy protein E9
643862 SPDYE10; speedy/RINGO cell cycle regulator family member E10
643909 SPDYE9; speedy/RINGO cell cycle regulator family member E9
728524 SPDYE8; speedy/RINGO cell cycle regulator family member E8
105180390 SPDYE13; speedy/RINGO cell cycle regulator family member E13
641776 SPDYE14; speedy/RINGO cell cycle regulator family member E14
1017 CDK2; cyclin dependent kinase 2
983 CDK1; cyclin dependent kinase 1
890 CCNA2; cyclin A2
8900 CCNA1; cyclin A1
4342 MOS; MOS proto-oncogene, serine/threonine kinase
3320 HSP90AA1; heat shock protein 90 alpha family class A member 1
3326 HSP90AB1; heat shock protein 90 alpha family class B member 1
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
6197 RPS6KA3; ribosomal protein S6 kinase A3
6195 RPS6KA1; ribosomal protein S6 kinase A1
6196 RPS6KA2; ribosomal protein S6 kinase A2
27330 RPS6KA6; ribosomal protein S6 kinase A6
9088 PKMYT1; protein kinase, membrane associated tyrosine/threonine 1
891 CCNB1; cyclin B1
9133 CCNB2; cyclin B2
85417 CCNB3; cyclin B3
6793 STK10; serine/threonine kinase 10
5347 PLK1; polo like kinase 1
993 CDC25A; cell division cycle 25A
994 CDC25B; cell division cycle 25B
995 CDC25C; cell division cycle 25C
3630 INS; insulin
3479 IGF1; insulin like growth factor 1
3480 IGF1R; insulin like growth factor 1 receptor
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
5140 PDE3B; phosphodiesterase 3B
3845 KRAS; KRAS proto-oncogene, GTPase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
699 BUB1; BUB1 mitotic checkpoint serine/threonine kinase
8379 MAD1L1; mitotic arrest deficient 1 like 1
4085 MAD2L1; mitotic arrest deficient 2 like 1
10459 MAD2L2; mitotic arrest deficient 2 like 2
51343 FZR1; fizzy and cell division cycle 20 related 1
64682 ANAPC1; anaphase promoting complex subunit 1
29882 ANAPC2; anaphase promoting complex subunit 2
996 CDC27; cell division cycle 27
29945 ANAPC4; anaphase promoting complex subunit 4
51433 ANAPC5; anaphase promoting complex subunit 5
8881 CDC16; cell division cycle 16
51434 ANAPC7; anaphase promoting complex subunit 7
8697 CDC23; cell division cycle 23
10393 ANAPC10; anaphase promoting complex subunit 10
51529 ANAPC11; anaphase promoting complex subunit 11
246184 CDC26; cell division cycle 26
25847 ANAPC13; anaphase promoting complex subunit 13
25906 ANAPC15; anaphase promoting complex subunit 15
119504 ANAPC16; anaphase promoting complex subunit 16
3835 KIF22; kinesin family member 22
|
K08556 PGR; progesterone receptor
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K11481 AURKA; aurora kinase A [EC:2.7.11.1]
K02602 CPEB; cytoplasmic polyadenylation element-binding protein
K02602 CPEB; cytoplasmic polyadenylation element-binding protein
K02602 CPEB; cytoplasmic polyadenylation element-binding protein
K02602 CPEB; cytoplasmic polyadenylation element-binding protein
K08694 SPDY; speedy
K08694 SPDY; speedy
K08694 SPDY; speedy
K08694 SPDY; speedy
K08694 SPDY; speedy
K08694 SPDY; speedy
K08694 SPDY; speedy
K08694 SPDY; speedy
K08694 SPDY; speedy
K08694 SPDY; speedy
K08694 SPDY; speedy
K08694 SPDY; speedy
K08694 SPDY; speedy
K08694 SPDY; speedy
K08694 SPDY; speedy
K08694 SPDY; speedy
K08694 SPDY; speedy
K08694 SPDY; speedy
K08694 SPDY; speedy
K08694 SPDY; speedy
K08694 SPDY; speedy
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K04367 MOS; proto-oncogene serine/threonine-protein kinase mos [EC:2.7.11.1]
K04079 HSP90A; molecular chaperone HtpG
K04079 HSP90A; molecular chaperone HtpG
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K06633 PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1]
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K08837 STK10; serine/threonine kinase 10 [EC:2.7.11.1]
K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
K04526 INS; insulin
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K13296 PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:3.1.4.17]
K07827 KRAS; GTPase KRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K02178 BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
K06679 MAD1; mitotic spindle assembly checkpoint protein MAD1
K02537 MAD2; mitotic spindle assembly checkpoint protein MAD2
K13728 MAD2L2; mitotic spindle assembly checkpoint protein MAD2B
K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
K03348 APC1; anaphase-promoting complex subunit 1
K03349 APC2; anaphase-promoting complex subunit 2
K03350 APC3; anaphase-promoting complex subunit 3
K03351 APC4; anaphase-promoting complex subunit 4
K03352 APC5; anaphase-promoting complex subunit 5
K03353 APC6; anaphase-promoting complex subunit 6
K03354 APC7; anaphase-promoting complex subunit 7
K03355 APC8; anaphase-promoting complex subunit 8
K03357 APC10; anaphase-promoting complex subunit 10
K03358 APC11; anaphase-promoting complex subunit 11
K03359 APC12; anaphase-promoting complex subunit 12
K12456 APC13; anaphase-promoting complex subunit 13
K25228 APC15; anaphase-promoting complex subunit 15
K25229 APC16; anaphase-promoting complex subunit 16
K10403 KIF22; kinesin family member 22
|
04917 Prolactin signaling pathway [PATH:hsa04917]
|
04921 Oxytocin signaling pathway [PATH:hsa04921]
|
04926 Relaxin signaling pathway [PATH:hsa04926]
|
04935 Growth hormone synthesis, secretion and action [PATH:hsa04935]
|
04918 Thyroid hormone synthesis [PATH:hsa04918]
|
04919 Thyroid hormone signaling pathway [PATH:hsa04919]
|
04928 Parathyroid hormone synthesis, secretion and action [PATH:hsa04928]
|
846 CASR; calcium sensing receptor
2770 GNAI1; G protein subunit alpha i1
2773 GNAI3; G protein subunit alpha i3
2771 GNAI2; G protein subunit alpha i2
107 ADCY1; adenylate cyclase 1
108 ADCY2; adenylate cyclase 2
109 ADCY3; adenylate cyclase 3
196883 ADCY4; adenylate cyclase 4
111 ADCY5; adenylate cyclase 5
112 ADCY6; adenylate cyclase 6
113 ADCY7; adenylate cyclase 7
114 ADCY8; adenylate cyclase 8
115 ADCY9; adenylate cyclase 9
2776 GNAQ; G protein subunit alpha q
2767 GNA11; G protein subunit alpha 11
23236 PLCB1; phospholipase C beta 1
5330 PLCB2; phospholipase C beta 2
5331 PLCB3; phospholipase C beta 3
5332 PLCB4; phospholipase C beta 4
3708 ITPR1; inositol 1,4,5-trisphosphate receptor type 1
3709 ITPR2; inositol 1,4,5-trisphosphate receptor type 2
3710 ITPR3; inositol 1,4,5-trisphosphate receptor type 3
8521 GCM1; glial cells missing transcription factor 1
9247 GCM2; glial cells missing transcription factor 2
9935 MAFB; MAF bZIP transcription factor B
2625 GATA3; GATA binding protein 3
6667 SP1; Sp1 transcription factor
7421 VDR; vitamin D receptor
6256 RXRA; retinoid X receptor alpha
6257 RXRB; retinoid X receptor beta
6258 RXRG; retinoid X receptor gamma
8074 FGF23; fibroblast growth factor 23
2260 FGFR1; fibroblast growth factor receptor 1
9365 KL; klotho
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
1958 EGR1; early growth response 1
5741 PTH; parathyroid hormone
6446 SGK1; serum/glucocorticoid regulated kinase 1
65125 WNK1; WNK lysine deficient protein kinase 1
65266 WNK4; WNK lysine deficient protein kinase 4
65267 WNK3; WNK lysine deficient protein kinase 3
65268 WNK2; WNK lysine deficient protein kinase 2
9943 OXSR1; oxidative stress responsive kinase 1
27347 STK39; serine/threonine kinase 39
6559 SLC12A3; solute carrier family 12 member 3
5744 PTHLH; parathyroid hormone like hormone
5745 PTH1R; parathyroid hormone 1 receptor
5578 PRKCA; protein kinase C alpha
5579 PRKCB; protein kinase C beta
5582 PRKCG; protein kinase C gamma
56302 TRPV5; transient receptor potential cation channel subfamily V member 5
6569 SLC34A1; solute carrier family 34 member 1
10568 SLC34A2; solute carrier family 34 member 2
142680 SLC34A3; solute carrier family 34 member 3
9368 NHERF1; NHERF family PDZ scaffold protein 1
2778 GNAS; GNAS complex locus
5141 PDE4A; phosphodiesterase 4A
5142 PDE4B; phosphodiesterase 4B
5143 PDE4C; phosphodiesterase 4C
5144 PDE4D; phosphodiesterase 4D
5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
1594 CYP27B1; cytochrome P450 family 27 subfamily B member 1
1591 CYP24A1; cytochrome P450 family 24 subfamily A member 1
4205 MEF2A; myocyte enhancer factor 2A
4208 MEF2C; myocyte enhancer factor 2C
4209 MEF2D; myocyte enhancer factor 2D
50964 SOST; sclerostin
4929 NR4A2; nuclear receptor subfamily 4 group A member 2
4666 NACA; nascent polypeptide associated complex subunit alpha
3727 JUND; JunD proto-oncogene, AP-1 transcription factor subunit
632 BGLAP; bone gamma-carboxyglutamate protein
4041 LRP5; LDL receptor related protein 5
4040 LRP6; LDL receptor related protein 6
1385 CREB1; cAMP responsive element binding protein 1
1386 ATF2; activating transcription factor 2
10488 CREB3; cAMP responsive element binding protein 3
90993 CREB3L1; cAMP responsive element binding protein 3 like 1
64764 CREB3L2; cAMP responsive element binding protein 3 like 2
84699 CREB3L3; cAMP responsive element binding protein 3 like 3
148327 CREB3L4; cAMP responsive element binding protein 3 like 4
468 ATF4; activating transcription factor 4
9586 CREB5; cAMP responsive element binding protein 5
1388 ATF6B; activating transcription factor 6 beta
8600 TNFSF11; TNF superfamily member 11
596 BCL2; BCL2 apoptosis regulator
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
2353 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
860 RUNX2; RUNX family transcription factor 2
4322 MMP13; matrix metallopeptidase 13
2768 GNA12; G protein subunit alpha 12
10672 GNA13; G protein subunit alpha 13
9138 ARHGEF1; Rho guanine nucleotide exchange factor 1
9826 ARHGEF11; Rho guanine nucleotide exchange factor 11
11214 AKAP13; A-kinase anchoring protein 13
387 RHOA; ras homolog family member A
5337 PLD1; phospholipase D1
5338 PLD2; phospholipase D2
408 ARRB1; arrestin beta 1
409 ARRB2; arrestin beta 2
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
4323 MMP14; matrix metallopeptidase 14
4324 MMP15; matrix metallopeptidase 15
4325 MMP16; matrix metallopeptidase 16
4326 MMP17; matrix metallopeptidase 17
10893 MMP24; matrix metallopeptidase 24
64386 MMP25; matrix metallopeptidase 25
1839 HBEGF; heparin binding EGF like growth factor
1956 EGFR; epidermal growth factor receptor
|
K04612 CASR; calcium-sensing receptor
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K21598 GCM; chorion-specific transcription factor GCM
K21598 GCM; chorion-specific transcription factor GCM
K09036 MAFB; transcription factor MAFB
K17895 GATA3; GATA-binding protein 3
K04684 SP1; transcription factor Sp1
K08539 VDR; vitamin D3 receptor
K08524 RXRA; retinoid X receptor alpha
K08525 RXRB; retinoid X receptor beta
K08526 RXRG; retinoid X receptor gamma
K22428 FGF23; fibroblast growth factor 23
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K14756 KL; klotho [EC:3.2.1.31]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K09203 EGR1; early growth response protein 1
K05261 PTH; parathyroid hormone
K13302 SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
K08867 WNK; WNK lysine deficient protein kinase [EC:2.7.11.1]
K08867 WNK; WNK lysine deficient protein kinase [EC:2.7.11.1]
K08867 WNK; WNK lysine deficient protein kinase [EC:2.7.11.1]
K08867 WNK; WNK lysine deficient protein kinase [EC:2.7.11.1]
K08835 OXSR1; serine/threonine-protein kinase OSR1/STK39 [EC:2.7.11.1]
K08835 OXSR1; serine/threonine-protein kinase OSR1/STK39 [EC:2.7.11.1]
K14426 SLC12A3; solute carrier family 12 (sodium/chloride transporter), member 3
K22608 PTHLH; parathyroid hormone-related hormone
K04585 PTH1R; parathyroid hormone receptor 1
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04974 TRPV5; transient receptor potential cation channel subfamily V member 5
K14683 SLC34A; solute carrier family 34 (sodium-dependent phosphate cotransporter)
K14683 SLC34A; solute carrier family 34 (sodium-dependent phosphate cotransporter)
K14683 SLC34A; solute carrier family 34 (sodium-dependent phosphate cotransporter)
K13365 SLC9A3R1; sodium/hydrogen exchange regulatory cofactor NHE-RF1
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K13293 PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
K13293 PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
K13293 PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
K13293 PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K07438 CYP27B1; calcidiol 1-monooxygenase (25-hydroxyvitamin D3 1alpha-hydroxylase) [EC:1.14.15.18]
K07436 CYP24A1; vitamin D3 24-hydroxylase [EC:1.14.15.16]
K09260 MEF2A; MADS-box transcription enhancer factor 2A
K04454 MEF2C; MADS-box transcription enhancer factor 2C
K09262 MEF2D; MADS-box transcription enhancer factor 2D
K16834 SOST; sclerostin
K08558 NR4A2; nuclear receptor subfamily 4 group A member 2
K03626 EGD2; nascent polypeptide-associated complex subunit alpha
K04449 JUND; transcription factor jun-D
K22609 BGLAP; osteocalcin
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2; cyclic AMP-dependent transcription factor ATF-2
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
K09047 CREB5; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B; cyclic AMP-dependent transcription factor ATF-6 beta
K05473 TNFSF11; tumor necrosis factor ligand superfamily member 11
K02161 BCL2; apoptosis regulator Bcl-2
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04379 FOS; proto-oncogene protein c-fos
K09278 RUNX2; runt-related transcription factor 2
K07994 MMP13; matrix metalloproteinase-13 (collagenase 3) [EC:3.4.24.-]
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K12331 ARHGEF11; Rho guanine nucleotide exchange factor 11
K16529 ARHGEF13; A-kinase anchor protein 13
K04513 RHOA; Ras homolog gene family, member A
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K04439 ARRB; beta-arrestin
K04439 ARRB; beta-arrestin
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K07763 MMP14; matrix metalloproteinase-14 (membrane-inserted) [EC:3.4.24.80]
K07995 MMP15; matrix metalloproteinase-15 (membrane-inserted) [EC:3.4.24.-]
K07996 MMP16; matrix metalloproteinase-16 (membrane-inserted) [EC:3.4.24.-]
K07997 MMP17; matrix metalloproteinase-17 (membrane-inserted) [EC:3.4.24.-]
K08002 MMP24; matrix metalloproteinase-24 (membrane-inserted) [EC:3.4.24.-]
K08003 MMP25; matrix metalloproteinase-25 (membrane-inserted) [EC:3.4.24.-]
K08523 HBEGF; heparin-binding EGF-like growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
|
04916 Melanogenesis [PATH:hsa04916]
|
04924 Renin secretion [PATH:hsa04924]
|
04614 Renin-angiotensin system [PATH:hsa04614]
|
04925 Aldosterone synthesis and secretion [PATH:hsa04925]
|
04927 Cortisol synthesis and secretion [PATH:hsa04927]
|
|
|
09153 Circulatory system
|
04260 Cardiac muscle contraction [PATH:hsa04260]
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04261 Adrenergic signaling in cardiomyocytes [PATH:hsa04261]
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04270 Vascular smooth muscle contraction [PATH:hsa04270]
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148 ADRA1A; adrenoceptor alpha 1A
147 ADRA1B; adrenoceptor alpha 1B
146 ADRA1D; adrenoceptor alpha 1D
183 AGT; angiotensinogen
185 AGTR1; angiotensin II receptor type 1
1906 EDN1; endothelin 1
1907 EDN2; endothelin 2
1908 EDN3; endothelin 3
1909 EDNRA; endothelin receptor type A
551 AVP; arginine vasopressin
552 AVPR1A; arginine vasopressin receptor 1A
553 AVPR1B; arginine vasopressin receptor 1B
2776 GNAQ; G protein subunit alpha q
2767 GNA11; G protein subunit alpha 11
8399 PLA2G10; phospholipase A2 group X
26279 PLA2G2D; phospholipase A2 group IID
30814 PLA2G2E; phospholipase A2 group IIE
50487 PLA2G3; phospholipase A2 group III
64600 PLA2G2F; phospholipase A2 group IIF
81579 PLA2G12A; phospholipase A2 group XIIA
84647 PLA2G12B; phospholipase A2 group XIIB
5319 PLA2G1B; phospholipase A2 group IB
5322 PLA2G5; phospholipase A2 group V
5320 PLA2G2A; phospholipase A2 group IIA
391013 PLA2G2C; phospholipase A2 group IIC
123745 PLA2G4E; phospholipase A2 group IVE
5321 PLA2G4A; phospholipase A2 group IVA
8681 JMJD7-PLA2G4B; JMJD7-PLA2G4B readthrough
100137049 PLA2G4B; phospholipase A2 group IVB
8605 PLA2G4C; phospholipase A2 group IVC
283748 PLA2G4D; phospholipase A2 group IVD
255189 PLA2G4F; phospholipase A2 group IVF
8398 PLA2G6; phospholipase A2 group VI
3778 KCNMA1; potassium calcium-activated channel subfamily M alpha 1
157855 KCNU1; potassium calcium-activated channel subfamily U member 1
3779 KCNMB1; potassium calcium-activated channel subfamily M regulatory beta subunit 1
10242 KCNMB2; potassium calcium-activated channel subfamily M regulatory beta subunit 2
27094 KCNMB3; potassium calcium-activated channel subfamily M regulatory beta subunit 3
27345 KCNMB4; potassium calcium-activated channel subfamily M regulatory beta subunit 4
775 CACNA1C; calcium voltage-gated channel subunit alpha1 C
776 CACNA1D; calcium voltage-gated channel subunit alpha1 D
778 CACNA1F; calcium voltage-gated channel subunit alpha1 F
779 CACNA1S; calcium voltage-gated channel subunit alpha1 S
810 CALML3; calmodulin like 3
805 CALM2; calmodulin 2
808 CALM3; calmodulin 3
801 CALM1; calmodulin 1
163688 CALML6; calmodulin like 6
51806 CALML5; calmodulin like 5
91860 CALML4; calmodulin like 4
4638 MYLK; myosin light chain kinase
85366 MYLK2; myosin light chain kinase 2
91807 MYLK3; myosin light chain kinase 3
340156 MYLK4; myosin light chain kinase family member 4
140465 MYL6B; myosin light chain 6B
4637 MYL6; myosin light chain 6
10398 MYL9; myosin light chain 9
4627 MYH9; myosin heavy chain 9
4628 MYH10; myosin heavy chain 10
4629 MYH11; myosin heavy chain 11
79784 MYH14; myosin heavy chain 14
23236 PLCB1; phospholipase C beta 1
5330 PLCB2; phospholipase C beta 2
5331 PLCB3; phospholipase C beta 3
5332 PLCB4; phospholipase C beta 4
3708 ITPR1; inositol 1,4,5-trisphosphate receptor type 1
3709 ITPR2; inositol 1,4,5-trisphosphate receptor type 2
3710 ITPR3; inositol 1,4,5-trisphosphate receptor type 3
5578 PRKCA; protein kinase C alpha
5579 PRKCB; protein kinase C beta
5582 PRKCG; protein kinase C gamma
5580 PRKCD; protein kinase C delta
5581 PRKCE; protein kinase C epsilon
5583 PRKCH; protein kinase C eta
5588 PRKCQ; protein kinase C theta
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
800 CALD1; caldesmon 1
59 ACTA2; actin alpha 2, smooth muscle
72 ACTG2; actin gamma 2, smooth muscle
94274 PPP1R14A; protein phosphatase 1 regulatory inhibitor subunit 14A
5499 PPP1CA; protein phosphatase 1 catalytic subunit alpha
5500 PPP1CB; protein phosphatase 1 catalytic subunit beta
5501 PPP1CC; protein phosphatase 1 catalytic subunit gamma
4659 PPP1R12A; protein phosphatase 1 regulatory subunit 12A
4660 PPP1R12B; protein phosphatase 1 regulatory subunit 12B
54776 PPP1R12C; protein phosphatase 1 regulatory subunit 12C
2768 GNA12; G protein subunit alpha 12
10672 GNA13; G protein subunit alpha 13
23365 ARHGEF12; Rho guanine nucleotide exchange factor 12
9138 ARHGEF1; Rho guanine nucleotide exchange factor 1
9826 ARHGEF11; Rho guanine nucleotide exchange factor 11
387 RHOA; ras homolog family member A
6093 ROCK1; Rho associated coiled-coil containing protein kinase 1
9475 ROCK2; Rho associated coiled-coil containing protein kinase 2
135 ADORA2A; adenosine A2a receptor
136 ADORA2B; adenosine A2b receptor
5739 PTGIR; prostaglandin I2 receptor
796 CALCA; calcitonin related polypeptide alpha
797 CALCB; calcitonin related polypeptide beta
133 ADM; adrenomedullin
79924 ADM2; adrenomedullin 2
10203 CALCRL; calcitonin receptor like receptor
10267 RAMP1; receptor activity modifying protein 1
10266 RAMP2; receptor activity modifying protein 2
10268 RAMP3; receptor activity modifying protein 3
2778 GNAS; GNAS complex locus
107 ADCY1; adenylate cyclase 1
108 ADCY2; adenylate cyclase 2
109 ADCY3; adenylate cyclase 3
196883 ADCY4; adenylate cyclase 4
111 ADCY5; adenylate cyclase 5
112 ADCY6; adenylate cyclase 6
113 ADCY7; adenylate cyclase 7
114 ADCY8; adenylate cyclase 8
115 ADCY9; adenylate cyclase 9
5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
4878 NPPA; natriuretic peptide A
4879 NPPB; natriuretic peptide B
4881 NPR1; natriuretic peptide receptor 1
4880 NPPC; natriuretic peptide C
4882 NPR2; natriuretic peptide receptor 2
5592 PRKG1; protein kinase cGMP-dependent 1
10335 IRAG1; inositol 1,4,5-triphosphate receptor associated 1
2977 GUCY1A2; guanylate cyclase 1 soluble subunit alpha 2
2982 GUCY1A1; guanylate cyclase 1 soluble subunit alpha 1
2983 GUCY1B1; guanylate cyclase 1 soluble subunit beta 1
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K04135 ADRA1A; adrenergic receptor alpha-1A
K04136 ADRA1B; adrenergic receptor alpha-1B
K04137 ADRA1D; adrenergic receptor alpha-1D
K09821 AGT; angiotensinogen
K04166 AGTR1; angiotensin II receptor type 1
K16366 EDN1; endothelin-1
K16367 EDN2; endothelin-2
K05227 EDN3; endothelin-3
K04197 EDNRA; endothelin receptor type A
K05242 AVP; arginine vasopressin
K04226 AVPR1A; arginine vasopressin receptor 1A
K04227 AVPR1B; arginine vasopressin receptor 1B
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16343 PLA2G6; calcium-independent phospholipase A2 [EC:3.1.1.4]
K04936 KCNMA1; potassium large conductance calcium-activated channel subfamily M alpha member 1
K05274 KCNMA3; potassium large conductance calcium-activated channel subfamily M alpha member 3
K04937 KCNMB1; potassium large conductance calcium-activated channel subfamily M beta member 1
K04938 KCNMB2; potassium large conductance calcium-activated channel subfamily M beta member 2
K04939 KCNMB3; potassium large conductance calcium-activated channel subfamily M beta member 3
K04941 KCNMB4; potassium large conductance calcium-activated channel subfamily M beta member 4
K04850 CACNA1C; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S; voltage-dependent calcium channel L type alpha-1S
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K12751 MYL6; myosin light chain 6
K12751 MYL6; myosin light chain 6
K12755 MYL9; myosin regulatory light chain 9
K10352 MYH9s; myosin heavy chain 9/10/11/14
K10352 MYH9s; myosin heavy chain 9/10/11/14
K10352 MYH9s; myosin heavy chain 9/10/11/14
K10352 MYH9s; myosin heavy chain 9/10/11/14
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K18051 PRKCH; novel protein kinase C eta type [EC:2.7.11.13]
K18052 PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K12327 CALD1; caldesmon
K12313 ACTA2; actin, aortic smooth muscle
K12315 ACTG2; actin, gamma-enteric smooth muscle
K12328 PPP1R14A; protein phosphatase 1 regulatory subunit 14A
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06270 PPP1R12A; protein phosphatase 1 regulatory subunit 12A
K12329 PPP1R12B; protein phosphatase 1 regulatory subunit 12B
K17457 PPP1R12C; protein phosphatase 1 regulatory subunit 12C
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K07532 ARHGEF12; Rho guanine nucleotide exchange factor 12
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K12331 ARHGEF11; Rho guanine nucleotide exchange factor 11
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K04266 ADORA2A; adenosine receptor A2a
K04267 ADORA2B; adenosine receptor A2b
K04263 PTGIR; prostacyclin receptor
K12332 CALC; calcitonin
K12332 CALC; calcitonin
K12333 ADM; adrenomedullin
K25343 ADM2; adrenomedullin-2
K04577 CALCRL; calcitonin receptor-like
K08447 RAMP1; receptor activity modifying protein 1
K08448 RAMP2; receptor activity modifying protein 2
K08449 RAMP3; receptor activity modifying protein 3
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K12334 NPPA; natriuretic peptide A
K12335 NPPB; natriuretic peptide B
K12323 ANPRA; atrial natriuretic peptide receptor A [EC:4.6.1.2]
K12336 NPPC; natriuretic peptide C
K12324 ANPRB; atrial natriuretic peptide receptor B [EC:4.6.1.2]
K07376 PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]
K12337 MRVI1; inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate
K12318 GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
K12318 GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
K12319 GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
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09154 Digestive system
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09155 Excretory system
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09156 Nervous system
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04724 Glutamatergic synapse [PATH:hsa04724]
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04727 GABAergic synapse [PATH:hsa04727]
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04725 Cholinergic synapse [PATH:hsa04725]
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04728 Dopaminergic synapse [PATH:hsa04728]
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04726 Serotonergic synapse [PATH:hsa04726]
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121278 TPH2; tryptophan hydroxylase 2
7166 TPH1; tryptophan hydroxylase 1
1644 DDC; dopa decarboxylase
6570 SLC18A1; solute carrier family 18 member A1
6571 SLC18A2; solute carrier family 18 member A2
775 CACNA1C; calcium voltage-gated channel subunit alpha1 C
776 CACNA1D; calcium voltage-gated channel subunit alpha1 D
778 CACNA1F; calcium voltage-gated channel subunit alpha1 F
779 CACNA1S; calcium voltage-gated channel subunit alpha1 S
3356 HTR2A; 5-hydroxytryptamine receptor 2A
3357 HTR2B; 5-hydroxytryptamine receptor 2B
3358 HTR2C; 5-hydroxytryptamine receptor 2C
2776 GNAQ; G protein subunit alpha q
23236 PLCB1; phospholipase C beta 1
5330 PLCB2; phospholipase C beta 2
5331 PLCB3; phospholipase C beta 3
5332 PLCB4; phospholipase C beta 4
3708 ITPR1; inositol 1,4,5-trisphosphate receptor type 1
3709 ITPR2; inositol 1,4,5-trisphosphate receptor type 2
3710 ITPR3; inositol 1,4,5-trisphosphate receptor type 3
5578 PRKCA; protein kinase C alpha
5579 PRKCB; protein kinase C beta
5582 PRKCG; protein kinase C gamma
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
123745 PLA2G4E; phospholipase A2 group IVE
5321 PLA2G4A; phospholipase A2 group IVA
8681 JMJD7-PLA2G4B; JMJD7-PLA2G4B readthrough
100137049 PLA2G4B; phospholipase A2 group IVB
8605 PLA2G4C; phospholipase A2 group IVC
283748 PLA2G4D; phospholipase A2 group IVD
255189 PLA2G4F; phospholipase A2 group IVF
1558 CYP2C8; cytochrome P450 family 2 subfamily C member 8
1559 CYP2C9; cytochrome P450 family 2 subfamily C member 9
1562 CYP2C18; cytochrome P450 family 2 subfamily C member 18
1557 CYP2C19; cytochrome P450 family 2 subfamily C member 19
1565 CYP2D6; cytochrome P450 family 2 subfamily D member 6
107987478 cytochrome P450 2D6-like
1564 CYP2D7; cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)
107987479 CYP2D6; cytochrome P450 2D6
1573 CYP2J2; cytochrome P450 family 2 subfamily J member 2
260293 CYP4X1; cytochrome P450 family 4 subfamily X member 1
240 ALOX5; arachidonate 5-lipoxygenase
239 ALOX12; arachidonate 12-lipoxygenase, 12S type
242 ALOX12B; arachidonate 12-lipoxygenase, 12R type
246 ALOX15; arachidonate 15-lipoxygenase
247 ALOX15B; arachidonate 15-lipoxygenase type B
5742 PTGS1; prostaglandin-endoperoxide synthase 1
5743 PTGS2; prostaglandin-endoperoxide synthase 2
3359 HTR3A; 5-hydroxytryptamine receptor 3A
285242 HTR3E; 5-hydroxytryptamine receptor 3E
200909 HTR3D; 5-hydroxytryptamine receptor 3D
170572 HTR3C; 5-hydroxytryptamine receptor 3C
9177 HTR3B; 5-hydroxytryptamine receptor 3B
3360 HTR4; 5-hydroxytryptamine receptor 4
3362 HTR6; 5-hydroxytryptamine receptor 6
3363 HTR7; 5-hydroxytryptamine receptor 7
2778 GNAS; GNAS complex locus
111 ADCY5; adenylate cyclase 5
5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
3781 KCNN2; potassium calcium-activated channel subfamily N member 2
3751 KCND2; potassium voltage-gated channel subfamily D member 2
2560 GABRB1; gamma-aminobutyric acid type A receptor subunit beta1
2562 GABRB3; gamma-aminobutyric acid type A receptor subunit beta3
2561 GABRB2; gamma-aminobutyric acid type A receptor subunit beta2
10411 RAPGEF3; Rap guanine nucleotide exchange factor 3
351 APP; amyloid beta precursor protein
3350 HTR1A; 5-hydroxytryptamine receptor 1A
3351 HTR1B; 5-hydroxytryptamine receptor 1B
3352 HTR1D; 5-hydroxytryptamine receptor 1D
3354 HTR1E; 5-hydroxytryptamine receptor 1E
3355 HTR1F; 5-hydroxytryptamine receptor 1F
3361 HTR5A; 5-hydroxytryptamine receptor 5A
2770 GNAI1; G protein subunit alpha i1
2773 GNAI3; G protein subunit alpha i3
2771 GNAI2; G protein subunit alpha i2
2775 GNAO1; G protein subunit alpha o1
2782 GNB1; G protein subunit beta 1
2783 GNB2; G protein subunit beta 2
2784 GNB3; G protein subunit beta 3
59345 GNB4; G protein subunit beta 4
10681 GNB5; G protein subunit beta 5
54331 GNG2; G protein subunit gamma 2
2785 GNG3; G protein subunit gamma 3
2786 GNG4; G protein subunit gamma 4
2787 GNG5; G protein subunit gamma 5
2788 GNG7; G protein subunit gamma 7
94235 GNG8; G protein subunit gamma 8
2790 GNG10; G protein subunit gamma 10
2791 GNG11; G protein subunit gamma 11
55970 GNG12; G protein subunit gamma 12
51764 GNG13; G protein subunit gamma 13
2792 GNGT1; G protein subunit gamma transducin 1
2793 GNGT2; G protein subunit gamma transducin 2
836 CASP3; caspase 3
1843 DUSP1; dual specificity phosphatase 1
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
773 CACNA1A; calcium voltage-gated channel subunit alpha1 A
774 CACNA1B; calcium voltage-gated channel subunit alpha1 B
3760 KCNJ3; potassium inwardly rectifying channel subfamily J member 3
3763 KCNJ6; potassium inwardly rectifying channel subfamily J member 6
3765 KCNJ9; potassium inwardly rectifying channel subfamily J member 9
3762 KCNJ5; potassium inwardly rectifying channel subfamily J member 5
7220 TRPC1; transient receptor potential cation channel subfamily C member 1
6532 SLC6A4; solute carrier family 6 member 4
4129 MAOB; monoamine oxidase B
4128 MAOA; monoamine oxidase A
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K00502 TPH1_2; tryptophan 5-monooxygenase [EC:1.14.16.4]
K00502 TPH1_2; tryptophan 5-monooxygenase [EC:1.14.16.4]
K01593 DDC; aromatic-L-amino-acid/L-tryptophan decarboxylase [EC:4.1.1.28 4.1.1.105]
K08155 SLC18A1_2; MFS transporter, DHA1 family, solute carrier family 18 (vesicular amine transporter), member 1/2
K08155 SLC18A1_2; MFS transporter, DHA1 family, solute carrier family 18 (vesicular amine transporter), member 1/2
K04850 CACNA1C; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S; voltage-dependent calcium channel L type alpha-1S
K04157 HTR2; 5-hydroxytryptamine receptor 2
K04157 HTR2; 5-hydroxytryptamine receptor 2
K04157 HTR2; 5-hydroxytryptamine receptor 2
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K17718 CYP2C8; cytochrome P450 family 2 subfamily C8 [EC:1.14.14.1]
K17719 CYP2C9; cytochrome P450 family 2 subfamily C9 [EC:1.14.14.51 1.14.14.52 1.14.14.53 1.14.14.-]
K17720 CYP2C18; cytochrome P450 family 2 subfamily C18 [EC:1.14.14.1]
K17721 CYP2C19; cytochrome P450 family 2 subfamily C19 [EC:1.14.14.51 1.14.14.52 1.14.14.53 1.14.14.75 1.14.14.-]
K17712 CYP2D6; cytochrome P450 family 2 subfamily D6 [EC:1.14.14.1]
K17712 CYP2D6; cytochrome P450 family 2 subfamily D6 [EC:1.14.14.1]
K17712 CYP2D6; cytochrome P450 family 2 subfamily D6 [EC:1.14.14.1]
K17712 CYP2D6; cytochrome P450 family 2 subfamily D6 [EC:1.14.14.1]
K07418 CYP2J; cytochrome P450 family 2 subfamily J [EC:1.14.14.1 1.14.14.73 1.14.14.74 1.14.14.75]
K07428 CYP4X; cytochrome P450 family 4 subfamily X [EC:1.14.14.1]
K00461 ALOX5; arachidonate 5-lipoxygenase [EC:1.13.11.34]
K00458 ALOX12; arachidonate 12-lipoxygenase [EC:1.13.11.31]
K08021 ALOX12B; arachidonate 12-lipoxygenase (R-type) [EC:1.13.11.-]
K00460 ALOX15; arachidonate 15-lipoxygenase [EC:1.13.11.33]
K08022 ALOX15B; arachidonate 15-lipoxygenase (second type) / 8-lipoxygenase (S-type) [EC:1.13.11.33 1.13.11.-]
K00509 PTGS1; prostaglandin-endoperoxide synthase 1 [EC:1.14.99.1]
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K04819 HTR3; 5-hydroxytryptamine receptor 3
K04819 HTR3; 5-hydroxytryptamine receptor 3
K04819 HTR3; 5-hydroxytryptamine receptor 3
K04819 HTR3; 5-hydroxytryptamine receptor 3
K04819 HTR3; 5-hydroxytryptamine receptor 3
K04160 HTR4; 5-hydroxytryptamine receptor 4
K04162 HTR6; 5-hydroxytryptamine receptor 6
K04163 HTR7; 5-hydroxytryptamine receptor 7
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04943 KCNN2; potassium intermediate/small conductance calcium-activated channel subfamily N member 2
K04892 KCND2; potassium voltage-gated channel Shal-related subfamily D member 2
K05181 GABRB; gamma-aminobutyric acid receptor subunit beta
K05181 GABRB; gamma-aminobutyric acid receptor subunit beta
K05181 GABRB; gamma-aminobutyric acid receptor subunit beta
K08014 RAPGEF3; Rap guanine nucleotide exchange factor 3
K04520 APP; amyloid beta A4 protein
K04153 HTR1; 5-hydroxytryptamine receptor 1
K04153 HTR1; 5-hydroxytryptamine receptor 1
K04153 HTR1; 5-hydroxytryptamine receptor 1
K04153 HTR1; 5-hydroxytryptamine receptor 1
K04153 HTR1; 5-hydroxytryptamine receptor 1
K04161 HTR5; 5-hydroxytryptamine receptor 5
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO; guanine nucleotide-binding protein G(o) subunit alpha
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K21278 DUSP1; dual specificity protein phosphatase 1 [EC:3.1.3.16 3.1.3.48]
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04344 CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
K04849 CACNA1B; voltage-dependent calcium channel N type alpha-1B
K04997 KCNJ3; potassium inwardly-rectifying channel subfamily J member 3
K05000 KCNJ6; potassium inwardly-rectifying channel subfamily J member 6
K05002 KCNJ9; potassium inwardly-rectifying channel subfamily J member 9
K04999 KCNJ5; potassium inwardly-rectifying channel subfamily J member 5
K04964 TRPC1; transient receptor potential cation channel subfamily C member 1
K05037 SLC6A4; solute carrier family 6 (neurotransmitter transporter, serotonin) member 4
K00274 MAO; monoamine oxidase [EC:1.4.3.4]
K00274 MAO; monoamine oxidase [EC:1.4.3.4]
|
04720 Long-term potentiation [PATH:hsa04720]
|
2890 GRIA1; glutamate ionotropic receptor AMPA type subunit 1
2891 GRIA2; glutamate ionotropic receptor AMPA type subunit 2
107 ADCY1; adenylate cyclase 1
114 ADCY8; adenylate cyclase 8
5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
5502 PPP1R1A; protein phosphatase 1 regulatory inhibitor subunit 1A
5499 PPP1CA; protein phosphatase 1 catalytic subunit alpha
5500 PPP1CB; protein phosphatase 1 catalytic subunit beta
5501 PPP1CC; protein phosphatase 1 catalytic subunit gamma
815 CAMK2A; calcium/calmodulin dependent protein kinase II alpha
817 CAMK2D; calcium/calmodulin dependent protein kinase II delta
816 CAMK2B; calcium/calmodulin dependent protein kinase II beta
818 CAMK2G; calcium/calmodulin dependent protein kinase II gamma
10411 RAPGEF3; Rap guanine nucleotide exchange factor 3
5906 RAP1A; RAP1A, member of RAS oncogene family
5908 RAP1B; RAP1B, member of RAS oncogene family
5530 PPP3CA; protein phosphatase 3 catalytic subunit alpha
5532 PPP3CB; protein phosphatase 3 catalytic subunit beta
5533 PPP3CC; protein phosphatase 3 catalytic subunit gamma
5534 PPP3R1; protein phosphatase 3 regulatory subunit B, alpha
5535 PPP3R2; protein phosphatase 3 regulatory subunit B, beta
2902 GRIN1; glutamate ionotropic receptor NMDA type subunit 1
2903 GRIN2A; glutamate ionotropic receptor NMDA type subunit 2A
2904 GRIN2B; glutamate ionotropic receptor NMDA type subunit 2B
2905 GRIN2C; glutamate ionotropic receptor NMDA type subunit 2C
2906 GRIN2D; glutamate ionotropic receptor NMDA type subunit 2D
775 CACNA1C; calcium voltage-gated channel subunit alpha1 C
810 CALML3; calmodulin like 3
805 CALM2; calmodulin 2
808 CALM3; calmodulin 3
801 CALM1; calmodulin 1
163688 CALML6; calmodulin like 6
51806 CALML5; calmodulin like 5
91860 CALML4; calmodulin like 4
1387 CREBBP; CREB binding protein
2033 EP300; E1A binding protein p300
468 ATF4; activating transcription factor 4
814 CAMK4; calcium/calmodulin dependent protein kinase IV
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
6197 RPS6KA3; ribosomal protein S6 kinase A3
6195 RPS6KA1; ribosomal protein S6 kinase A1
6196 RPS6KA2; ribosomal protein S6 kinase A2
27330 RPS6KA6; ribosomal protein S6 kinase A6
3708 ITPR1; inositol 1,4,5-trisphosphate receptor type 1
3709 ITPR2; inositol 1,4,5-trisphosphate receptor type 2
3710 ITPR3; inositol 1,4,5-trisphosphate receptor type 3
5578 PRKCA; protein kinase C alpha
5579 PRKCB; protein kinase C beta
5582 PRKCG; protein kinase C gamma
2911 GRM1; glutamate metabotropic receptor 1
2915 GRM5; glutamate metabotropic receptor 5
2776 GNAQ; G protein subunit alpha q
23236 PLCB1; phospholipase C beta 1
5330 PLCB2; phospholipase C beta 2
5331 PLCB3; phospholipase C beta 3
5332 PLCB4; phospholipase C beta 4
|
K05197 GRIA1; glutamate receptor 1
K05198 GRIA2; glutamate receptor 2
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K08050 PPP1R1A; protein phosphatase 1 regulatory subunit 1A
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K08014 RAPGEF3; Rap guanine nucleotide exchange factor 3
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K05211 GRIN2C; glutamate receptor ionotropic, NMDA 2C
K05212 GRIN2D; glutamate receptor ionotropic, NMDA 2D
K04850 CACNA1C; voltage-dependent calcium channel L type alpha-1C
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
K05869 CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04603 GRM1; metabotropic glutamate receptor 1
K04604 GRM5; metabotropic glutamate receptor 5
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
|
04730 Long-term depression [PATH:hsa04730]
|
4842 NOS1; nitric oxide synthase 1
2977 GUCY1A2; guanylate cyclase 1 soluble subunit alpha 2
2982 GUCY1A1; guanylate cyclase 1 soluble subunit alpha 1
2983 GUCY1B1; guanylate cyclase 1 soluble subunit beta 1
5592 PRKG1; protein kinase cGMP-dependent 1
5593 PRKG2; protein kinase cGMP-dependent 2
10842 PPP1R17; protein phosphatase 1 regulatory subunit 17
5519 PPP2R1B; protein phosphatase 2 scaffold subunit Abeta
5518 PPP2R1A; protein phosphatase 2 scaffold subunit Aalpha
5515 PPP2CA; protein phosphatase 2 catalytic subunit alpha
5516 PPP2CB; protein phosphatase 2 catalytic subunit beta
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
2895 GRID2; glutamate ionotropic receptor delta type subunit 2
2911 GRM1; glutamate metabotropic receptor 1
2770 GNAI1; G protein subunit alpha i1
2773 GNAI3; G protein subunit alpha i3
2771 GNAI2; G protein subunit alpha i2
2775 GNAO1; G protein subunit alpha o1
2781 GNAZ; G protein subunit alpha z
2778 GNAS; GNAS complex locus
2768 GNA12; G protein subunit alpha 12
10672 GNA13; G protein subunit alpha 13
123745 PLA2G4E; phospholipase A2 group IVE
5321 PLA2G4A; phospholipase A2 group IVA
8681 JMJD7-PLA2G4B; JMJD7-PLA2G4B readthrough
100137049 PLA2G4B; phospholipase A2 group IVB
8605 PLA2G4C; phospholipase A2 group IVC
283748 PLA2G4D; phospholipase A2 group IVD
255189 PLA2G4F; phospholipase A2 group IVF
5578 PRKCA; protein kinase C alpha
5579 PRKCB; protein kinase C beta
5582 PRKCG; protein kinase C gamma
2776 GNAQ; G protein subunit alpha q
2767 GNA11; G protein subunit alpha 11
23236 PLCB1; phospholipase C beta 1
5330 PLCB2; phospholipase C beta 2
5331 PLCB3; phospholipase C beta 3
5332 PLCB4; phospholipase C beta 4
2890 GRIA1; glutamate ionotropic receptor AMPA type subunit 1
2891 GRIA2; glutamate ionotropic receptor AMPA type subunit 2
2892 GRIA3; glutamate ionotropic receptor AMPA type subunit 3
4067 LYN; LYN proto-oncogene, Src family tyrosine kinase
773 CACNA1A; calcium voltage-gated channel subunit alpha1 A
3708 ITPR1; inositol 1,4,5-trisphosphate receptor type 1
3709 ITPR2; inositol 1,4,5-trisphosphate receptor type 2
3710 ITPR3; inositol 1,4,5-trisphosphate receptor type 3
6261 RYR1; ryanodine receptor 1
1392 CRH; corticotropin releasing hormone
1394 CRHR1; corticotropin releasing hormone receptor 1
3479 IGF1; insulin like growth factor 1
3480 IGF1R; insulin like growth factor 1 receptor
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K13240 NOS1; nitric-oxide synthase, brain [EC:1.14.13.39]
K12318 GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
K12318 GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
K12319 GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
K07376 PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]
K19477 PRKG2; cGMP-dependent protein kinase 2 [EC:2.7.11.12]
K08067 PPP1R17; protein phosphatase 1 regulatory subunit 17
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K05207 GRID2; glutamate receptor delta-2 subunit
K04603 GRM1; metabotropic glutamate receptor 1
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO; guanine nucleotide-binding protein G(o) subunit alpha
K04535 GNAZ; guanine nucleotide-binding protein G(z) subunit alpha
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05197 GRIA1; glutamate receptor 1
K05198 GRIA2; glutamate receptor 2
K05199 GRIA3; glutamate receptor 3
K05854 LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
K04344 CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04961 RYR1; ryanodine receptor 1
K05256 CRH; corticotropin-releasing hormone
K04578 CRHR1; corticotropin releasing hormone receptor 1
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
|
04723 Retrograde endocannabinoid signaling [PATH:hsa04723]
|
04721 Synaptic vesicle cycle [PATH:hsa04721]
|
04722 Neurotrophin signaling pathway [PATH:hsa04722]
|
4803 NGF; nerve growth factor
627 BDNF; brain derived neurotrophic factor
4909 NTF4; neurotrophin 4
4908 NTF3; neurotrophin 3
4914 NTRK1; neurotrophic receptor tyrosine kinase 1
4915 NTRK2; neurotrophic receptor tyrosine kinase 2
4916 NTRK3; neurotrophic receptor tyrosine kinase 3
10603 SH2B2; SH2B adaptor protein 2
25970 SH2B1; SH2B adaptor protein 1
10019 SH2B3; SH2B adaptor protein 3
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
6197 RPS6KA3; ribosomal protein S6 kinase A3
6195 RPS6KA1; ribosomal protein S6 kinase A1
6196 RPS6KA2; ribosomal protein S6 kinase A2
27330 RPS6KA6; ribosomal protein S6 kinase A6
9252 RPS6KA5; ribosomal protein S6 kinase A5
468 ATF4; activating transcription factor 4
596 BCL2; BCL2 apoptosis regulator
57498 KIDINS220; kinase D interacting substrate 220
10818 FRS2; fibroblast growth factor receptor substrate 2
1398 CRK; CRK proto-oncogene, adaptor protein
1399 CRKL; CRK like proto-oncogene, adaptor protein
2889 RAPGEF1; Rap guanine nucleotide exchange factor 1
5906 RAP1A; RAP1A, member of RAS oncogene family
5908 RAP1B; RAP1B, member of RAS oncogene family
4215 MAP3K3; mitogen-activated protein kinase kinase kinase 3
5607 MAP2K5; mitogen-activated protein kinase kinase 5
5598 MAPK7; mitogen-activated protein kinase 7
5600 MAPK11; mitogen-activated protein kinase 11
6300 MAPK12; mitogen-activated protein kinase 12
5603 MAPK13; mitogen-activated protein kinase 13
1432 MAPK14; mitogen-activated protein kinase 14
9261 MAPKAPK2; MAPK activated protein kinase 2
6464 SHC1; SHC adaptor protein 1
25759 SHC2; SHC adaptor protein 2
53358 SHC3; SHC adaptor protein 3
399694 SHC4; SHC adaptor protein 4
2549 GAB1; GRB2 associated binding protein 1
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
4793 NFKBIB; NFKB inhibitor beta
4792 NFKBIA; NFKB inhibitor alpha
4794 NFKBIE; NFKB inhibitor epsilon
4790 NFKB1; nuclear factor kappa B subunit 1
5970 RELA; RELA proto-oncogene, NF-kB subunit
2309 FOXO3; forkhead box O3
356 FASLG; Fas ligand
572 BAD; BCL2 associated agonist of cell death
2932 GSK3B; glycogen synthase kinase 3 beta
5170 PDPK1; 3-phosphoinositide dependent protein kinase 1
3667 IRS1; insulin receptor substrate 1
5335 PLCG1; phospholipase C gamma 1
5336 PLCG2; phospholipase C gamma 2
5580 PRKCD; protein kinase C delta
810 CALML3; calmodulin like 3
805 CALM2; calmodulin 2
808 CALM3; calmodulin 3
801 CALM1; calmodulin 1
163688 CALML6; calmodulin like 6
51806 CALML5; calmodulin like 5
91860 CALML4; calmodulin like 4
815 CAMK2A; calcium/calmodulin dependent protein kinase II alpha
817 CAMK2D; calcium/calmodulin dependent protein kinase II delta
816 CAMK2B; calcium/calmodulin dependent protein kinase II beta
818 CAMK2G; calcium/calmodulin dependent protein kinase II gamma
814 CAMK4; calcium/calmodulin dependent protein kinase IV
25 ABL1; ABL proto-oncogene 1, non-receptor tyrosine kinase
5781 PTPN11; protein tyrosine phosphatase non-receptor type 11
4145 MATK; megakaryocyte-associated tyrosine kinase
4804 NGFR; nerve growth factor receptor
397 ARHGDIB; Rho GDP dissociation inhibitor beta
396 ARHGDIA; Rho GDP dissociation inhibitor alpha
398 ARHGDIG; Rho GDP dissociation inhibitor gamma
387 RHOA; ras homolog family member A
998 CDC42; cell division cycle 42
5879 RAC1; Rac family small GTPase 1
4214 MAP3K1; mitogen-activated protein kinase kinase kinase 1
4217 MAP3K5; mitogen-activated protein kinase kinase kinase 5
5609 MAP2K7; mitogen-activated protein kinase kinase 7
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
7157 TP53; tumor protein p53
581 BAX; BCL2 associated X, apoptosis regulator
7161 TP73; tumor protein p73
7189 TRAF6; TNF receptor associated factor 6
10782 ZNF274; zinc finger protein 274
11108 PRDM4; PR/SET domain 4
9500 MAGED1; MAGE family member D1
27018 BEX3; brain expressed X-linked 3
7531 YWHAE; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
8767 RIPK2; receptor interacting serine/threonine kinase 2
3654 IRAK1; interleukin 1 receptor associated kinase 1
3656 IRAK2; interleukin 1 receptor associated kinase 2
11213 IRAK3; interleukin 1 receptor associated kinase 3
51135 IRAK4; interleukin 1 receptor associated kinase 4
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
6272 SORT1; sortilin 1
5663 PSEN1; presenilin 1
5664 PSEN2; presenilin 2
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K02582 NGFB; nerve growth factor, beta
K04355 BDNF; brain-derived neurotrophic factor
K12457 NTF4; neurotrophin 4
K04356 NTF3; neurotrophin 3
K03176 NTRK1; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K04360 NTRK2; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
K05101 NTRK3; neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1]
K07193 SH2B; SH2B adapter protein 2
K12459 SH2B1_3; SH2B adaptor protein 1/3
K12459 SH2B1_3; SH2B adaptor protein 1/3
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
K02161 BCL2; apoptosis regulator Bcl-2
K12460 KIDINS220; ankyrin repeat-rich membrane spanning protein
K12461 FRS2; fibroblast growth factor receptor substrate 2
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K06277 RAPGEF1; Rap guanine nucleotide exchange factor 1
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K04421 MAP3K3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
K04463 MAP2K5; mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K09593 GAB1; GRB2-associated-binding protein 1
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02581 NFKBIB; NF-kappa-B inhibitor beta
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K05872 NFKBIE; NF-kappa-B inhibitor epsilon
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K09408 FOXO3; forkhead box protein O3
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K02158 BAD; Bcl-2-antagonist of cell death
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K16172 IRS1; insulin receptor substrate 1
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K05869 CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K08888 MATK; megakaryocyte-associated tyrosine kinase [EC:2.7.10.2]
K02583 NGFR; tumor necrosis factor receptor superfamily member 16
K12462 ARHGDI; Rho GDP-dissociation inhibitor
K12462 ARHGDI; Rho GDP-dissociation inhibitor
K12462 ARHGDI; Rho GDP-dissociation inhibitor
K04513 RHOA; Ras homolog gene family, member A
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04451 TP53; tumor protein p53
K02159 BAX; apoptosis regulator BAX
K10148 TP73; tumor protein p73
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K12458 ZNF274; zinc finger protein 274
K12463 PRDM4; PR domain zinc finger protein 4 [EC:2.1.1.-]
K12464 MAGED1; melanoma-associated antigen D1
K12465 NGFRAP1; nerve growth factor receptor-associated protein 1
K06630 YWHAE; 14-3-3 protein epsilon
K08846 RIPK2; receptor-interacting serine/threonine-protein kinase 2 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04731 IRAK2; interleukin-1 receptor-associated kinase 2 [EC:2.7.11.1]
K04732 IRAK3; interleukin-1 receptor-associated kinase 3 [EC:2.7.11.1]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K12388 SORT1; sortilin
K04505 PSEN1; presenilin 1 [EC:3.4.23.-]
K04522 PSEN2; presenilin 2 [EC:3.4.23.-]
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09157 Sensory system
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09158 Development and regeneration
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09149 Aging
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09159 Environmental adaptation
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09160 Human Diseases
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09161 Cancer: overview
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05200 Pathways in cancer [PATH:hsa05200]
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1630 DCC; DCC netrin 1 receptor
836 CASP3; caspase 3
842 CASP9; caspase 9
26060 APPL1; adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
999 CDH1; cadherin 1
1499 CTNNB1; catenin beta 1
29119 CTNNA3; catenin alpha 3
1495 CTNNA1; catenin alpha 1
1496 CTNNA2; catenin alpha 2
8312 AXIN1; axin 1
8313 AXIN2; axin 2
324 APC; APC regulator of WNT signaling pathway
10297 APC2; APC regulator of WNT signaling pathway 2
2932 GSK3B; glycogen synthase kinase 3 beta
6932 TCF7; transcription factor 7
83439 TCF7L1; transcription factor 7 like 1
6934 TCF7L2; transcription factor 7 like 2
51176 LEF1; lymphoid enhancer binding factor 1
332 BIRC5; baculoviral IAP repeat containing 5
4609 MYC; MYC proto-oncogene, bHLH transcription factor
595 CCND1; cyclin D1
7471 WNT1; Wnt family member 1
7472 WNT2; Wnt family member 2
7482 WNT2B; Wnt family member 2B
7473 WNT3; Wnt family member 3
89780 WNT3A; Wnt family member 3A
54361 WNT4; Wnt family member 4
7474 WNT5A; Wnt family member 5A
81029 WNT5B; Wnt family member 5B
7475 WNT6; Wnt family member 6
7476 WNT7A; Wnt family member 7A
7477 WNT7B; Wnt family member 7B
7478 WNT8A; Wnt family member 8A
7479 WNT8B; Wnt family member 8B
7483 WNT9A; Wnt family member 9A
7484 WNT9B; Wnt family member 9B
7480 WNT10B; Wnt family member 10B
80326 WNT10A; Wnt family member 10A
7481 WNT11; Wnt family member 11
51384 WNT16; Wnt family member 16
8321 FZD1; frizzled class receptor 1
8324 FZD7; frizzled class receptor 7
2535 FZD2; frizzled class receptor 2
7976 FZD3; frizzled class receptor 3
8322 FZD4; frizzled class receptor 4
7855 FZD5; frizzled class receptor 5
8325 FZD8; frizzled class receptor 8
8323 FZD6; frizzled class receptor 6
11211 FZD10; frizzled class receptor 10
8326 FZD9; frizzled class receptor 9
4041 LRP5; LDL receptor related protein 5
4040 LRP6; LDL receptor related protein 6
1857 DVL3; dishevelled segment polarity protein 3
1856 DVL2; dishevelled segment polarity protein 2
1855 DVL1; dishevelled segment polarity protein 1
10023 FRAT1; FRAT regulator of WNT signaling pathway 1
23401 FRAT2; FRAT regulator of WNT signaling pathway 2
2147 F2; coagulation factor II, thrombin
183 AGT; angiotensinogen
2149 F2R; coagulation factor II thrombin receptor
9002 F2RL3; F2R like thrombin or trypsin receptor 3
1902 LPAR1; lysophosphatidic acid receptor 1
9170 LPAR2; lysophosphatidic acid receptor 2
23566 LPAR3; lysophosphatidic acid receptor 3
2846 LPAR4; lysophosphatidic acid receptor 4
57121 LPAR5; lysophosphatidic acid receptor 5
10161 LPAR6; lysophosphatidic acid receptor 6
185 AGTR1; angiotensin II receptor type 1
2768 GNA12; G protein subunit alpha 12
10672 GNA13; G protein subunit alpha 13
23365 ARHGEF12; Rho guanine nucleotide exchange factor 12
9826 ARHGEF11; Rho guanine nucleotide exchange factor 11
9138 ARHGEF1; Rho guanine nucleotide exchange factor 1
57449 PLEKHG5; pleckstrin homology and RhoGEF domain containing G5
387 RHOA; ras homolog family member A
6093 ROCK1; Rho associated coiled-coil containing protein kinase 1
9475 ROCK2; Rho associated coiled-coil containing protein kinase 2
6387 CXCL12; C-X-C motif chemokine ligand 12
7852 CXCR4; C-X-C motif chemokine receptor 4
2770 GNAI1; G protein subunit alpha i1
2773 GNAI3; G protein subunit alpha i3
2771 GNAI2; G protein subunit alpha i2
5731 PTGER1; prostaglandin E receptor 1
5732 PTGER2; prostaglandin E receptor 2
5733 PTGER3; prostaglandin E receptor 3
5734 PTGER4; prostaglandin E receptor 4
2778 GNAS; GNAS complex locus
107 ADCY1; adenylate cyclase 1
108 ADCY2; adenylate cyclase 2
109 ADCY3; adenylate cyclase 3
196883 ADCY4; adenylate cyclase 4
111 ADCY5; adenylate cyclase 5
112 ADCY6; adenylate cyclase 6
113 ADCY7; adenylate cyclase 7
114 ADCY8; adenylate cyclase 8
115 ADCY9; adenylate cyclase 9
5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
2782 GNB1; G protein subunit beta 1
2783 GNB2; G protein subunit beta 2
2784 GNB3; G protein subunit beta 3
59345 GNB4; G protein subunit beta 4
10681 GNB5; G protein subunit beta 5
54331 GNG2; G protein subunit gamma 2
2785 GNG3; G protein subunit gamma 3
2786 GNG4; G protein subunit gamma 4
2787 GNG5; G protein subunit gamma 5
2788 GNG7; G protein subunit gamma 7
94235 GNG8; G protein subunit gamma 8
2790 GNG10; G protein subunit gamma 10
2791 GNG11; G protein subunit gamma 11
55970 GNG12; G protein subunit gamma 12
51764 GNG13; G protein subunit gamma 13
2792 GNGT1; G protein subunit gamma transducin 1
2793 GNGT2; G protein subunit gamma transducin 2
1284 COL4A2; collagen type IV alpha 2 chain
1286 COL4A4; collagen type IV alpha 4 chain
1288 COL4A6; collagen type IV alpha 6 chain
1282 COL4A1; collagen type IV alpha 1 chain
1287 COL4A5; collagen type IV alpha 5 chain
1285 COL4A3; collagen type IV alpha 3 chain
284217 LAMA1; laminin subunit alpha 1
3908 LAMA2; laminin subunit alpha 2
3909 LAMA3; laminin subunit alpha 3
3911 LAMA5; laminin subunit alpha 5
3910 LAMA4; laminin subunit alpha 4
3912 LAMB1; laminin subunit beta 1
3913 LAMB2; laminin subunit beta 2
3914 LAMB3; laminin subunit beta 3
22798 LAMB4; laminin subunit beta 4
3915 LAMC1; laminin subunit gamma 1
3918 LAMC2; laminin subunit gamma 2
10319 LAMC3; laminin subunit gamma 3
2335 FN1; fibronectin 1
3673 ITGA2; integrin subunit alpha 2
3674 ITGA2B; integrin subunit alpha 2b
3675 ITGA3; integrin subunit alpha 3
3655 ITGA6; integrin subunit alpha 6
3685 ITGAV; integrin subunit alpha V
3688 ITGB1; integrin subunit beta 1
5747 PTK2; protein tyrosine kinase 2
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
5728 PTEN; phosphatase and tensin homolog
4824 NKX3-1; NK3 homeobox 1
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
4792 NFKBIA; NFKB inhibitor alpha
4790 NFKB1; nuclear factor kappa B subunit 1
4791 NFKB2; nuclear factor kappa B subunit 2
5970 RELA; RELA proto-oncogene, NF-kB subunit
5743 PTGS2; prostaglandin-endoperoxide synthase 2
4843 NOS2; nitric oxide synthase 2
596 BCL2; BCL2 apoptosis regulator
329 BIRC2; baculoviral IAP repeat containing 2
330 BIRC3; baculoviral IAP repeat containing 3
331 XIAP; X-linked inhibitor of apoptosis
79444 BIRC7; baculoviral IAP repeat containing 7
598 BCL2L1; BCL2 like 1
7185 TRAF1; TNF receptor associated factor 1
7186 TRAF2; TNF receptor associated factor 2
7187 TRAF3; TNF receptor associated factor 3
9618 TRAF4; TNF receptor associated factor 4
7188 TRAF5; TNF receptor associated factor 5
7189 TRAF6; TNF receptor associated factor 6
2475 MTOR; mechanistic target of rapamycin kinase
6198 RPS6KB1; ribosomal protein S6 kinase B1
6199 RPS6KB2; ribosomal protein S6 kinase B2
572 BAD; BCL2 associated agonist of cell death
2308 FOXO1; forkhead box O1
4193 MDM2; MDM2 proto-oncogene
7157 TP53; tumor protein p53
1027 CDKN1B; cyclin dependent kinase inhibitor 1B
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
613 BCR; BCR activator of RhoGEF and GTPase
25 ABL1; ABL proto-oncogene 1, non-receptor tyrosine kinase
1398 CRK; CRK proto-oncogene, adaptor protein
1399 CRKL; CRK like proto-oncogene, adaptor protein
867 CBL; Cbl proto-oncogene
6776 STAT5A; signal transducer and activator of transcription 5A
6777 STAT5B; signal transducer and activator of transcription 5B
5292 PIM1; Pim-1 proto-oncogene, serine/threonine kinase
11040 PIM2; Pim-2 proto-oncogene, serine/threonine kinase
3827 KNG1; kininogen 1
1906 EDN1; endothelin 1
623 BDKRB1; bradykinin receptor B1
624 BDKRB2; bradykinin receptor B2
1909 EDNRA; endothelin receptor type A
1910 EDNRB; endothelin receptor type B
2776 GNAQ; G protein subunit alpha q
2767 GNA11; G protein subunit alpha 11
23236 PLCB1; phospholipase C beta 1
5330 PLCB2; phospholipase C beta 2
5331 PLCB3; phospholipase C beta 3
5332 PLCB4; phospholipase C beta 4
5578 PRKCA; protein kinase C alpha
5579 PRKCB; protein kinase C beta
5582 PRKCG; protein kinase C gamma
3558 IL2; interleukin 2
3562 IL3; interleukin 3
3565 IL4; interleukin 4
3567 IL5; interleukin 5
3569 IL6; interleukin 6
3574 IL7; interleukin 7
3592 IL12A; interleukin 12A
3593 IL12B; interleukin 12B
3596 IL13; interleukin 13
3600 IL15; interleukin 15
51561 IL23A; interleukin 23 subunit alpha
2056 EPO; erythropoietin
3439 IFNA1; interferon alpha 1
3440 IFNA2; interferon alpha 2
3441 IFNA4; interferon alpha 4
3442 IFNA5; interferon alpha 5
3443 IFNA6; interferon alpha 6
3444 IFNA7; interferon alpha 7
3445 IFNA8; interferon alpha 8
3446 IFNA10; interferon alpha 10
3447 IFNA13; interferon alpha 13
3448 IFNA14; interferon alpha 14
3449 IFNA16; interferon alpha 16
3451 IFNA17; interferon alpha 17
3452 IFNA21; interferon alpha 21
3458 IFNG; interferon gamma
3559 IL2RA; interleukin 2 receptor subunit alpha
3560 IL2RB; interleukin 2 receptor subunit beta
3561 IL2RG; interleukin 2 receptor subunit gamma
3563 IL3RA; interleukin 3 receptor subunit alpha
3566 IL4R; interleukin 4 receptor
1439 CSF2RB; colony stimulating factor 2 receptor subunit beta
3568 IL5RA; interleukin 5 receptor subunit alpha
3570 IL6R; interleukin 6 receptor
3572 IL6ST; interleukin 6 cytokine family signal transducer
3575 IL7R; interleukin 7 receptor
3594 IL12RB1; interleukin 12 receptor subunit beta 1
3595 IL12RB2; interleukin 12 receptor subunit beta 2
3597 IL13RA1; interleukin 13 receptor subunit alpha 1
3601 IL15RA; interleukin 15 receptor subunit alpha
149233 IL23R; interleukin 23 receptor
2057 EPOR; erythropoietin receptor
3454 IFNAR1; interferon alpha and beta receptor subunit 1
3455 IFNAR2; interferon alpha and beta receptor subunit 2
3459 IFNGR1; interferon gamma receptor 1
3460 IFNGR2; interferon gamma receptor 2
27436 EML4; EMAP like 4
238 ALK; ALK receptor tyrosine kinase
10125 RASGRP1; RAS guanyl releasing protein 1
10235 RASGRP2; RAS guanyl releasing protein 2
25780 RASGRP3; RAS guanyl releasing protein 3
115727 RASGRP4; RAS guanyl releasing protein 4
3716 JAK1; Janus kinase 1
3717 JAK2; Janus kinase 2
3718 JAK3; Janus kinase 3
6774 STAT3; signal transducer and activator of transcription 3
6772 STAT1; signal transducer and activator of transcription 1
6773 STAT2; signal transducer and activator of transcription 2
6775 STAT4; signal transducer and activator of transcription 4
6778 STAT6; signal transducer and activator of transcription 6
7422 VEGFA; vascular endothelial growth factor A
7423 VEGFB; vascular endothelial growth factor B
5228 PGF; placental growth factor
7424 VEGFC; vascular endothelial growth factor C
2277 VEGFD; vascular endothelial growth factor D
7039 TGFA; transforming growth factor alpha
1950 EGF; epidermal growth factor
1956 EGFR; epidermal growth factor receptor
2064 ERBB2; erb-b2 receptor tyrosine kinase 2
5154 PDGFA; platelet derived growth factor subunit A
5155 PDGFB; platelet derived growth factor subunit B
5156 PDGFRA; platelet derived growth factor receptor alpha
5159 PDGFRB; platelet derived growth factor receptor beta
3479 IGF1; insulin like growth factor 1
3481 IGF2; insulin like growth factor 2
3480 IGF1R; insulin like growth factor 1 receptor
4254 KITLG; KIT ligand
3815 KIT; KIT proto-oncogene, receptor tyrosine kinase
2323 FLT3LG; fms related receptor tyrosine kinase 3 ligand
2322 FLT3; fms related receptor tyrosine kinase 3
3082 HGF; hepatocyte growth factor
4233 MET; MET proto-oncogene, receptor tyrosine kinase
2246 FGF1; fibroblast growth factor 1
2247 FGF2; fibroblast growth factor 2
2248 FGF3; fibroblast growth factor 3
2249 FGF4; fibroblast growth factor 4
8822 FGF17; fibroblast growth factor 17
2251 FGF6; fibroblast growth factor 6
2252 FGF7; fibroblast growth factor 7
2253 FGF8; fibroblast growth factor 8
2254 FGF9; fibroblast growth factor 9
2255 FGF10; fibroblast growth factor 10
8823 FGF16; fibroblast growth factor 16
2250 FGF5; fibroblast growth factor 5
8817 FGF18; fibroblast growth factor 18
26281 FGF20; fibroblast growth factor 20
27006 FGF22; fibroblast growth factor 22
9965 FGF19; fibroblast growth factor 19
26291 FGF21; fibroblast growth factor 21
8074 FGF23; fibroblast growth factor 23
2260 FGFR1; fibroblast growth factor receptor 1
2263 FGFR2; fibroblast growth factor receptor 2
2261 FGFR3; fibroblast growth factor receptor 3
2264 FGFR4; fibroblast growth factor receptor 4
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
2353 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
2113 ETS1; ETS proto-oncogene 1, transcription factor
4312 MMP1; matrix metallopeptidase 1
4313 MMP2; matrix metallopeptidase 2
4318 MMP9; matrix metallopeptidase 9
3576 CXCL8; C-X-C motif chemokine ligand 8
1019 CDK4; cyclin dependent kinase 4
9252 RPS6KA5; ribosomal protein S6 kinase A5
5979 RET; ret proto-oncogene
8030 CCDC6; coiled-coil domain containing 6
8031 NCOA4; nuclear receptor coactivator 4
4914 NTRK1; neurotrophic receptor tyrosine kinase 1
7170 TPM3; tropomyosin 3
7175 TPR; translocated promoter region, nuclear basket protein
10342 TFG; trafficking from ER to golgi regulator
11186 RASSF1; Ras association domain family member 1
83593 RASSF5; Ras association domain family member 5
6789 STK4; serine/threonine kinase 4
1612 DAPK1; death associated protein kinase 1
1613 DAPK3; death associated protein kinase 3
23604 DAPK2; death associated protein kinase 2
5335 PLCG1; phospholipase C gamma 1
5336 PLCG2; phospholipase C gamma 2
2002 ELK1; ETS transcription factor ELK1
810 CALML3; calmodulin like 3
805 CALM2; calmodulin 2
808 CALM3; calmodulin 3
801 CALM1; calmodulin 1
163688 CALML6; calmodulin like 6
51806 CALML5; calmodulin like 5
91860 CALML4; calmodulin like 4
815 CAMK2A; calcium/calmodulin dependent protein kinase II alpha
817 CAMK2D; calcium/calmodulin dependent protein kinase II delta
816 CAMK2B; calcium/calmodulin dependent protein kinase II beta
818 CAMK2G; calcium/calmodulin dependent protein kinase II gamma
5900 RALGDS; ral guanine nucleotide dissociation stimulator
5898 RALA; RAS like proto-oncogene A
5899 RALB; RAS like proto-oncogene B
10928 RALBP1; ralA binding protein 1
998 CDC42; cell division cycle 42
5879 RAC1; Rac family small GTPase 1
5880 RAC2; Rac family small GTPase 2
5881 RAC3; Rac family small GTPase 3
5337 PLD1; phospholipase D1
5338 PLD2; phospholipase D2
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
7849 PAX8; paired box 8
5468 PPARG; peroxisome proliferator activated receptor gamma
6256 RXRA; retinoid X receptor alpha
6257 RXRB; retinoid X receptor beta
6258 RXRG; retinoid X receptor gamma
5915 RARB; retinoic acid receptor beta
2099 ESR1; estrogen receptor 1
2100 ESR2; estrogen receptor 2
8648 NCOA1; nuclear receptor coactivator 1
8202 NCOA3; nuclear receptor coactivator 3
6667 SP1; Sp1 transcription factor
5467 PPARD; peroxisome proliferator activated receptor delta
3728 JUP; junction plakoglobin
7704 ZBTB16; zinc finger and BTB domain containing 16
5914 RARA; retinoic acid receptor alpha
890 CCNA2; cyclin A2
8900 CCNA1; cyclin A1
5371 PML; PML nuclear body scaffold
861 RUNX1; RUNX family transcription factor 1
862 RUNX1T1; RUNX1 partner transcriptional co-repressor 1
6688 SPI1; Spi-1 proto-oncogene
1050 CEBPA; CCAAT enhancer binding protein alpha
1438 CSF2RA; colony stimulating factor 2 receptor subunit alpha
1441 CSF3R; colony stimulating factor 3 receptor
1436 CSF1R; colony stimulating factor 1 receptor
1029 CDKN2A; cyclin dependent kinase inhibitor 2A
1869 E2F1; E2F transcription factor 1
1870 E2F2; E2F transcription factor 2
1871 E2F3; E2F transcription factor 3
4149 MAX; MYC associated factor X
7709 ZBTB17; zinc finger and BTB domain containing 17
1030 CDKN2B; cyclin dependent kinase inhibitor 2B
1021 CDK6; cyclin dependent kinase 6
894 CCND2; cyclin D2
896 CCND3; cyclin D3
1163 CKS1B; CDC28 protein kinase regulatory subunit 1B
1164 CKS2; CDC28 protein kinase regulatory subunit 2
6500 SKP1; S-phase kinase associated protein 1
8454 CUL1; cullin 1
9978 RBX1; ring-box 1
6502 SKP2; S-phase kinase associated protein 2
1017 CDK2; cyclin dependent kinase 2
898 CCNE1; cyclin E1
9134 CCNE2; cyclin E2
5925 RB1; RB transcriptional corepressor 1
1647 GADD45A; growth arrest and DNA damage inducible alpha
4616 GADD45B; growth arrest and DNA damage inducible beta
10912 GADD45G; growth arrest and DNA damage inducible gamma
581 BAX; BCL2 associated X, apoptosis regulator
578 BAK1; BCL2 antagonist/killer 1
1643 DDB2; damage specific DNA binding protein 2
51426 POLK; DNA polymerase kappa
7015 TERT; telomerase reverse transcriptase
7012 TERC; telomerase RNA component
4286 MITF; melanocyte inducing transcription factor
7040 TGFB1; transforming growth factor beta 1
7042 TGFB2; transforming growth factor beta 2
7043 TGFB3; transforming growth factor beta 3
7046 TGFBR1; transforming growth factor beta receptor 1
7048 TGFBR2; transforming growth factor beta receptor 2
4087 SMAD2; SMAD family member 2
4088 SMAD3; SMAD family member 3
4089 SMAD4; SMAD family member 4
2122 MECOM; MDS1 and EVI1 complex locus
1487 CTBP1; C-terminal binding protein 1
1488 CTBP2; C-terminal binding protein 2
3065 HDAC1; histone deacetylase 1
3066 HDAC2; histone deacetylase 2
4292 MLH1; mutL homolog 1
4436 MSH2; mutS homolog 2
4437 MSH3; mutS homolog 3
2956 MSH6; mutS homolog 6
675 BRCA2; BRCA2 DNA repair associated
5888 RAD51; RAD51 recombinase
356 FASLG; Fas ligand
355 FAS; Fas cell surface death receptor
8772 FADD; Fas associated via death domain
841 CASP8; caspase 8
637 BID; BH3 interacting domain death agonist
5366 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
27113 BBC3; BCL2 binding component 3
10018 BCL2L11; BCL2 like 11
54205 CYCS; cytochrome c, somatic
317 APAF1; apoptotic peptidase activating factor 1
840 CASP7; caspase 7
9817 KEAP1; kelch like ECH associated protein 1
4780 NFE2L2; NFE2 like bZIP transcription factor 2
3162 HMOX1; heme oxygenase 1
1728 NQO1; NAD(P)H quinone dehydrogenase 1
221357 GSTA5; glutathione S-transferase alpha 5
2939 GSTA2; glutathione S-transferase alpha 2
2941 GSTA4; glutathione S-transferase alpha 4
119391 GSTO2; glutathione S-transferase omega 2
2948 GSTM4; glutathione S-transferase mu 4
2953 GSTT2; glutathione S-transferase theta 2 (gene/pseudogene)
2952 GSTT1; glutathione S-transferase theta 1
2947 GSTM3; glutathione S-transferase mu 3
4257 MGST1; microsomal glutathione S-transferase 1
4259 MGST3; microsomal glutathione S-transferase 3
2944 GSTM1; glutathione S-transferase mu 1
2949 GSTM5; glutathione S-transferase mu 5
4258 MGST2; microsomal glutathione S-transferase 2
2938 GSTA1; glutathione S-transferase alpha 1
2946 GSTM2; glutathione S-transferase mu 2
2940 GSTA3; glutathione S-transferase alpha 3
9446 GSTO1; glutathione S-transferase omega 1
653689 GSTT2B; glutathione S-transferase theta 2B
2950 GSTP1; glutathione S-transferase pi 1
7296 TXNRD1; thioredoxin reductase 1
114112 TXNRD3; thioredoxin reductase 3
10587 TXNRD2; thioredoxin reductase 2
7428 VHL; von Hippel-Lindau tumor suppressor
6921 ELOC; elongin C
6923 ELOB; elongin B
8453 CUL2; cullin 2
54583 EGLN1; egl-9 family hypoxia inducible factor 1
112399 EGLN3; egl-9 family hypoxia inducible factor 3
112398 EGLN2; egl-9 family hypoxia inducible factor 2
2271 FH; fumarate hydratase
3091 HIF1A; hypoxia inducible factor 1 subunit alpha
2034 EPAS1; endothelial PAS domain protein 1
405 ARNT; aryl hydrocarbon receptor nuclear translocator
9915 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
1387 CREBBP; CREB binding protein
2033 EP300; E1A binding protein p300
6513 SLC2A1; solute carrier family 2 member 1
182 JAG1; jagged canonical Notch ligand 1
3714 JAG2; jagged canonical Notch ligand 2
10683 DLL3; delta like canonical Notch ligand 3
28514 DLL1; delta like canonical Notch ligand 1
54567 DLL4; delta like canonical Notch ligand 4
4851 NOTCH1; notch receptor 1
4853 NOTCH2; notch receptor 2
4854 NOTCH3; notch receptor 3
4855 NOTCH4; notch receptor 4
3280 HES1; hes family bHLH transcription factor 1
388585 HES5; hes family bHLH transcription factor 5
26508 HEYL; hes related family bHLH transcription factor with YRPW motif like
23462 HEY1; hes related family bHLH transcription factor with YRPW motif 1
23493 HEY2; hes related family bHLH transcription factor with YRPW motif 2
2324 FLT4; fms related receptor tyrosine kinase 4
6469 SHH; sonic hedgehog signaling molecule
5727 PTCH1; patched 1
6608 SMO; smoothened, frizzled class receptor
374654 KIF7; kinesin family member 7
51684 SUFU; SUFU negative regulator of hedgehog signaling
2735 GLI1; GLI family zinc finger 1
2736 GLI2; GLI family zinc finger 2
2737 GLI3; GLI family zinc finger 3
650 BMP2; bone morphogenetic protein 2
652 BMP4; bone morphogenetic protein 4
64399 HHIP; hedgehog interacting protein
8643 PTCH2; patched 2
367 AR; androgen receptor
3320 HSP90AA1; heat shock protein 90 alpha family class A member 1
3326 HSP90AB1; heat shock protein 90 alpha family class B member 1
7184 HSP90B1; heat shock protein 90 beta family member 1
354 KLK3; kallikrein related peptidase 3
|
K06765 DCC; deleted in colorectal carcinoma
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K08733 APPL1; DCC-interacting protein 13 alpha
K05689 CDH1; cadherin 1, type 1, E-cadherin
K02105 CTNNB1; catenin beta 1
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
K09821 AGT; angiotensinogen
K03914 F2R; coagulation factor II (thrombin) receptor
K04236 F2RL3; coagulation factor II (thrombin) receptor-like 3
K04289 LPAR1; lysophosphatidic acid receptor 1
K04291 LPAR2; lysophosphatidic acid receptor 2
K04294 LPAR3; lysophosphatidic acid receptor 3
K04275 LPAR4; lysophosphatidic acid receptor 4
K08390 LPAR5; lysophosphatidic acid receptor 5
K04273 LPAR6; lysophosphatidic acid receptor 6
K04166 AGTR1; angiotensin II receptor type 1
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K07532 ARHGEF12; Rho guanine nucleotide exchange factor 12
K12331 ARHGEF11; Rho guanine nucleotide exchange factor 11
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K19464 PLEKHG5; pleckstrin homology domain-containing family G member 5
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4; C-X-C chemokine receptor type 4
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04258 PTGER1; prostaglandin E receptor 1
K04259 PTGER2; prostaglandin E receptor 2
K04260 PTGER3; prostaglandin E receptor 3
K04261 PTGER4; prostaglandin E receptor 4
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K05637 LAMA1_2; laminin, alpha 1/2
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K05717 FN1; fibronectin 1
K06481 ITGA2; integrin alpha 2
K06476 ITGA2B; integrin alpha 2B
K06482 ITGA3; integrin alpha 3
K06485 ITGA6; integrin alpha 6
K06487 ITGAV; integrin alpha V
K05719 ITGB1; integrin beta 1
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K09348 NKX3-1; homeobox protein Nkx-3.1
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K04735 RELA; transcription factor p65
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K02161 BCL2; apoptosis regulator Bcl-2
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K03172 TRAF1; TNF receptor-associated factor 1
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K03174 TRAF3; TNF receptor-associated factor 3
K09848 TRAF4; TNF receptor-associated factor 4
K09849 TRAF5; TNF receptor-associated factor 5
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K07201 FOXO1; forkhead box protein O1
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K08878 BCR1; breakpoint cluster region protein [EC:2.7.11.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K08806 PIM2; proto-oncogene serine/threonine-protein kinase Pim-2 [EC:2.7.11.1]
K03898 KNG; kininogen
K16366 EDN1; endothelin-1
K03915 BDKRB1; bradykinin receptor B1
K03916 BDKRB2; bradykinin receptor B2
K04197 EDNRA; endothelin receptor type A
K04198 EDNRB; endothelin receptor type B
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05405 IL6; interleukin 6
K05431 IL7; interleukin 7
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05435 IL13; interleukin 13
K05433 IL15; interleukin 15
K05426 IL23A; interleukin 23 subunit alpha
K05437 EPO; erythropoietin
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K04687 IFNG; interferon gamma
K05068 IL2RA; interleukin 2 receptor alpha
K05069 IL2RB; interleukin 2 receptor beta
K05070 IL2RG; interleukin 2 receptor gamma
K04737 IL3RA; interleukin 3 receptor alpha
K05071 IL4R; interleukin 4 receptor
K04738 CSF2RB; cytokine receptor common subunit beta
K05067 IL5RA; interleukin 5 receptor alpha
K05055 IL6R; interleukin 6 receptor
K05060 IL6ST; interleukin 6 signal transducer
K05072 IL7R; interleukin 7 receptor
K05063 IL12RB1; interleukin 12 receptor beta-1
K05064 IL12RB2; interleukin 12 receptor beta-2
K05076 IL13RA1; interleukin 13 receptor alpha-1
K05074 IL15RA; interleukin 15 receptor alpha
K05065 IL23R; interleukin 23 receptor
K05079 EPOR; erythropoietin receptor
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05132 IFNGR1; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K15420 EML4; echinoderm microtubule-associated protein-like 4
K05119 ALK; anaplastic lymphoma kinase [EC:2.7.10.1]
K04350 RASGRP1; RAS guanyl-releasing protein 1
K12361 RASGRP2; RAS guanyl-releasing protein 2
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12363 RASGRP4; RAS guanyl-releasing protein 4
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K11222 STAT4; signal transducer and activator of transcription 4
K11225 STAT6; signal transducer and activator of transcription 6
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05449 VEGFC_D; vascular endothelial growth factor C/D
K08774 TGFA; transforming growth factor, alpha
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K05461 KITLG; KIT ligand
K05091 KIT; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05092 FLT3; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05460 HGF; hepatocyte growth factor
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K02678 ETS1; C-ets-1
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K10030 IL8; interleukin 8
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K09288 CCDC6; coiled-coil domain-containing protein 6
K09289 NCOA4; nuclear receptor coactivator 4
K03176 NTRK1; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K09290 TPM3; tropomyosin 3
K09291 TPR; nucleoprotein TPR
K09292 TFG; protein TFG
K09850 RASSF1; Ras association domain-containing protein 1
K08015 RASSF5; Ras association domain-containing protein 5
K04411 STK4; serine/threonine kinase 4
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04375 ELK1; ETS domain-containing protein Elk-1
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K08773 RALBP1; RalA-binding protein 1
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K09293 PAX8; paired box protein 8
K08530 NR1C3; peroxisome proliferator-activated receptor gamma
K08524 RXRA; retinoid X receptor alpha
K08525 RXRB; retinoid X receptor beta
K08526 RXRG; retinoid X receptor gamma
K08528 RARB; retinoic acid receptor beta
K08550 ESR1; estrogen receptor alpha
K08551 ESR2; estrogen receptor beta
K09101 NCOA1; nuclear receptor coactivator 1 [EC:2.3.1.48]
K11256 NCOA3; nuclear receptor coactivator 3 [EC:2.3.1.48]
K04684 SP1; transcription factor Sp1
K04504 NR1C2; peroxisome proliferator-activated receptor delta
K10056 JUP; junction plakoglobin
K10055 ZBTB16; zinc finger and BTB domain-containing protein 16
K08527 RARA; retinoic acid receptor alpha
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K10054 PML; E3 SUMO-protein ligase PML [EC:2.3.2.-]
K08367 RUNX1; runt-related transcription factor 1
K10053 RUNX1T1; CBFA2/RNUX1 translocation partner 1
K09438 SPI1; transcription factor PU.1
K09055 CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
K05066 CSF2RA; granulocyte-macrophage colony-stimulating factor receptor alpha
K05061 CSF3R; granulocyte colony-stimulating factor receptor
K05090 CSF1R; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04453 MAX; Max protein
K10500 ZBTB17; zinc finger and BTB domain-containing protein 17
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K03094 SKP1; S-phase kinase-associated protein 1
K03347 CUL1; cullin 1
K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
K22183 TERC; telomerase RNA component
K09455 MITF; microphthalmia-associated transcription factor
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04462 MECOM; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
K04496 CTBP; C-terminal binding protein [EC:1.1.1.428]
K04496 CTBP; C-terminal binding protein [EC:1.1.1.428]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K08734 MLH1; DNA mismatch repair protein MLH1
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K08775 BRCA2; breast cancer 2 susceptibility protein
K04482 RAD51; DNA repair protein RAD51
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K10132 BBC3; Bcl-2-binding component 3
K16341 BCL2L11; Bcl-2-like protein 11
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K10456 KLHL19; kelch-like protein 19
K05638 NFE2L2; nuclear factor erythroid 2-related factor 2
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K03871 VHL; von Hippel-Lindau disease tumor supressor
K03872 ELOC; elongin-C
K03873 ELOB; elongin-B
K03870 CUL2; cullin 2
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K09095 HIF2A; hypoxia-inducible factor 2 alpha
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K15589 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K07299 SLC2A1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K06052 JAG1; jagged-1
K21635 JAG2; jagged-2
K06051 DLL; delta
K06051 DLL; delta
K06051 DLL; delta
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K06054 HES1; hairy and enhancer of split 1
K06055 HES5; hairy and enhancer of split 5
K09091 HEY; hairy and enhancer of split related with YRPW motif
K09091 HEY; hairy and enhancer of split related with YRPW motif
K09091 HEY; hairy and enhancer of split related with YRPW motif
K05097 FLT4; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K11988 SHH; sonic hedgehog
K06225 PTCH1; patched 1
K06226 SMO; smoothened
K18806 KIF7; kinesin family member 7
K06229 SUFU; suppressor of fused
K16797 GLI1; zinc finger protein GLI1
K16798 GLI2; zinc finger protein GLI2
K06230 GLI3; zinc finger protein GLI3
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K06231 HHIP; hedgehog interacting protein
K11101 PTCH2; patched 2
K08557 AR; androgen receptor
K04079 HSP90A; molecular chaperone HtpG
K04079 HSP90A; molecular chaperone HtpG
K09487 HSP90B; heat shock protein 90kDa beta
K01351 KLK3; semenogelase [EC:3.4.21.77]
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05202 Transcriptional misregulation in cancer [PATH:hsa05202]
|
05206 MicroRNAs in cancer [PATH:hsa05206]
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05205 Proteoglycans in cancer [PATH:hsa05205]
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960 CD44; CD44 molecule (IN blood group)
6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase
2017 CTTN; cortactin
3059 HCLS1; hematopoietic cell-specific Lyn substrate 1
2064 ERBB2; erb-b2 receptor tyrosine kinase 2
2885 GRB2; growth factor receptor bound protein 2
10451 VAV3; vav guanine nucleotide exchange factor 3
7409 VAV1; vav guanine nucleotide exchange factor 1
7410 VAV2; vav guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
6237 RRAS; RAS related
22800 RRAS2; RAS related 2
22808 MRAS; muscle RAS oncogene homolog
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
5879 RAC1; Rac family small GTPase 1
8826 IQGAP1; IQ motif containing GTPase activating protein 1
998 CDC42; cell division cycle 42
2002 ELK1; ETS transcription factor ELK1
2099 ESR1; estrogen receptor 1
595 CCND1; cyclin D1
71 ACTG1; actin gamma 1
60 ACTB; actin beta
2316 FLNA; filamin A
5058 PAK1; p21 (RAC1) activated kinase 1
7074 TIAM1; TIAM Rac1 associated GEF 1
9138 ARHGEF1; Rho guanine nucleotide exchange factor 1
387 RHOA; ras homolog family member A
6093 ROCK1; Rho associated coiled-coil containing protein kinase 1
9475 ROCK2; Rho associated coiled-coil containing protein kinase 2
286 ANK1; ankyrin 1
287 ANK2; ankyrin 2
288 ANK3; ankyrin 3
2549 GAB1; GRB2 associated binding protein 1
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
6548 SLC9A1; solute carrier family 9 member A1
5499 PPP1CA; protein phosphatase 1 catalytic subunit alpha
5500 PPP1CB; protein phosphatase 1 catalytic subunit beta
5501 PPP1CC; protein phosphatase 1 catalytic subunit gamma
4659 PPP1R12A; protein phosphatase 1 regulatory subunit 12A
4660 PPP1R12B; protein phosphatase 1 regulatory subunit 12B
54776 PPP1R12C; protein phosphatase 1 regulatory subunit 12C
23365 ARHGEF12; Rho guanine nucleotide exchange factor 12
51196 PLCE1; phospholipase C epsilon 1
3708 ITPR1; inositol 1,4,5-trisphosphate receptor type 1
3709 ITPR2; inositol 1,4,5-trisphosphate receptor type 2
3710 ITPR3; inositol 1,4,5-trisphosphate receptor type 3
815 CAMK2A; calcium/calmodulin dependent protein kinase II alpha
817 CAMK2D; calcium/calmodulin dependent protein kinase II delta
816 CAMK2B; calcium/calmodulin dependent protein kinase II beta
818 CAMK2G; calcium/calmodulin dependent protein kinase II gamma
79923 NANOG; Nanog homeobox
388112 NANOGP8; Nanog homeobox retrogene P8
1655 DDX5; DEAD-box helicase 5
29102 DROSHA; drosha ribonuclease III
6774 STAT3; signal transducer and activator of transcription 3
406991 MIR21; microRNA 21
7291 TWIST1; twist family bHLH transcription factor 1
117581 TWIST2; twist family bHLH transcription factor 2
406902 MIR10A; microRNA 10a
406903 MIR10B; microRNA 10b
3236 HOXD10; homeobox D10
1634 DCN; decorin
3479 IGF1; insulin like growth factor 1
3480 IGF1R; insulin like growth factor 1 receptor
2475 MTOR; mechanistic target of rapamycin kinase
5170 PDPK1; 3-phosphoinositide dependent protein kinase 1
6198 RPS6KB1; ribosomal protein S6 kinase B1
6199 RPS6KB2; ribosomal protein S6 kinase B2
1975 EIF4B; eukaryotic translation initiation factor 4B
6194 RPS6; ribosomal protein S6
1956 EGFR; epidermal growth factor receptor
857 CAV1; caveolin 1
858 CAV2; caveolin 2
859 CAV3; caveolin 3
967 CD63; CD63 molecule
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
836 CASP3; caspase 3
7040 TGFB1; transforming growth factor beta 1
7097 TLR2; toll like receptor 2
7099 TLR4; toll like receptor 4
27250 PDCD4; programmed cell death 4
7124 TNF; tumor necrosis factor
3593 IL12B; interleukin 12B
2065 ERBB3; erb-b2 receptor tyrosine kinase 3
2066 ERBB4; erb-b2 receptor tyrosine kinase 4
4609 MYC; MYC proto-oncogene, bHLH transcription factor
1499 CTNNB1; catenin beta 1
3091 HIF1A; hypoxia inducible factor 1 subunit alpha
7023 TFAP4; transcription factor AP-4
7422 VEGFA; vascular endothelial growth factor A
3791 KDR; kinase insert domain receptor
4233 MET; MET proto-oncogene, receptor tyrosine kinase
867 CBL; Cbl proto-oncogene
7078 TIMP3; TIMP metallopeptidase inhibitor 3
7057 THBS1; thrombospondin 1
4313 MMP2; matrix metallopeptidase 2
4318 MMP9; matrix metallopeptidase 9
4060 LUM; lumican
356 FASLG; Fas ligand
355 FAS; Fas cell surface death receptor
4193 MDM2; MDM2 proto-oncogene
7157 TP53; tumor protein p53
7042 TGFB2; transforming growth factor beta 2
4087 SMAD2; SMAD family member 2
10855 HPSE; heparanase
60495 HPSE2; heparanase 2 (inactive)
6382 SDC1; syndecan 1
5328 PLAU; plasminogen activator, urokinase
5329 PLAUR; plasminogen activator, urokinase receptor
1277 COL1A1; collagen type I alpha 1 chain
1278 COL1A2; collagen type I alpha 2 chain
3673 ITGA2; integrin subunit alpha 2
3688 ITGB1; integrin subunit beta 1
7448 VTN; vitronectin
3685 ITGAV; integrin subunit alpha V
3690 ITGB3; integrin subunit beta 3
2335 FN1; fibronectin 1
3693 ITGB5; integrin subunit beta 5
3082 HGF; hepatocyte growth factor
7471 WNT1; Wnt family member 1
8321 FZD1; frizzled class receptor 1
8324 FZD7; frizzled class receptor 7
2535 FZD2; frizzled class receptor 2
7976 FZD3; frizzled class receptor 3
8322 FZD4; frizzled class receptor 4
7855 FZD5; frizzled class receptor 5
8325 FZD8; frizzled class receptor 8
8323 FZD6; frizzled class receptor 6
11211 FZD10; frizzled class receptor 10
8326 FZD9; frizzled class receptor 9
3678 ITGA5; integrin subunit alpha 5
6383 SDC2; syndecan 2
7430 EZR; ezrin
5962 RDX; radixin
4478 MSN; moesin
6385 SDC4; syndecan 4
2247 FGF2; fibroblast growth factor 2
2260 FGFR1; fibroblast growth factor receptor 1
10818 FRS2; fibroblast growth factor receptor substrate 2
5781 PTPN11; protein tyrosine phosphatase non-receptor type 11
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
5335 PLCG1; phospholipase C gamma 1
5336 PLCG2; phospholipase C gamma 2
5578 PRKCA; protein kinase C alpha
5579 PRKCB; protein kinase C beta
5582 PRKCG; protein kinase C gamma
84309 NUDT16L1; nudix hydrolase 16 like 1
5829 PXN; paxillin
5747 PTK2; protein tyrosine kinase 2
1839 HBEGF; heparin binding EGF like growth factor
2817 GPC1; glypican 1
3481 IGF2; insulin like growth factor 2
2719 GPC3; glypican 3
7472 WNT2; Wnt family member 2
7482 WNT2B; Wnt family member 2B
7473 WNT3; Wnt family member 3
89780 WNT3A; Wnt family member 3A
54361 WNT4; Wnt family member 4
7474 WNT5A; Wnt family member 5A
81029 WNT5B; Wnt family member 5B
7475 WNT6; Wnt family member 6
7476 WNT7A; Wnt family member 7A
7477 WNT7B; Wnt family member 7B
7478 WNT8A; Wnt family member 8A
7479 WNT8B; Wnt family member 8B
7483 WNT9A; Wnt family member 9A
7484 WNT9B; Wnt family member 9B
7480 WNT10B; Wnt family member 10B
80326 WNT10A; Wnt family member 10A
7481 WNT11; Wnt family member 11
51384 WNT16; Wnt family member 16
6469 SHH; sonic hedgehog signaling molecule
3549 IHH; Indian hedgehog signaling molecule
5727 PTCH1; patched 1
6608 SMO; smoothened, frizzled class receptor
3339 HSPG2; heparan sulfate proteoglycan 2
1514 CTSL; cathepsin L
5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
5600 MAPK11; mitogen-activated protein kinase 11
6300 MAPK12; mitogen-activated protein kinase 12
5603 MAPK13; mitogen-activated protein kinase 13
1432 MAPK14; mitogen-activated protein kinase 14
3316 HSPB2; heat shock protein family B (small) member 2
5777 PTPN6; protein tyrosine phosphatase non-receptor type 6
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K06256 CD44; CD44 antigen
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K06106 CTTN; cortactin
K06106 CTTN; cortactin
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2; Ras-related protein R-Ras2
K07831 MRAS; Ras-related protein M-Ras
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K16848 IQGAP1; Ras GTPase-activating-like protein IQGAP1
K04393 CDC42; cell division control protein 42
K04375 ELK1; ETS domain-containing protein Elk-1
K08550 ESR1; estrogen receptor alpha
K04503 CCND1; G1/S-specific cyclin-D1
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
K04437 FLNA; filamin-A
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K05731 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10380 ANK1; ankyrin-1
K09255 ANK2; ankyrin-2
K09259 ANK3; ankyrin-3
K09593 GAB1; GRB2-associated-binding protein 1
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K05742 SLC9A1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06270 PPP1R12A; protein phosphatase 1 regulatory subunit 12A
K12329 PPP1R12B; protein phosphatase 1 regulatory subunit 12B
K17457 PPP1R12C; protein phosphatase 1 regulatory subunit 12C
K07532 ARHGEF12; Rho guanine nucleotide exchange factor 12
K05860 PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K10164 NANOG; homeobox protein Nanog
K10164 NANOG; homeobox protein Nanog
K12823 DDX5; ATP-dependent RNA helicase DDX5/DBP2 [EC:5.6.2.7]
K03685 rnc; ribonuclease III [EC:3.1.26.3]
K04692 STAT3; signal transducer and activator of transcription 3
K16863 MIR21; microRNA 21
K09069 TWIST; twist
K09069 TWIST; twist
K16864 MIR10A; microRNA 10a
K17393 MIR10B; microRNA 10b
K09295 HOXD10; homrobox protein Hox-D10
K04660 DCN; decorin
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K03258 EIF4B; translation initiation factor 4B
K02991 RP-S6e; small subunit ribosomal protein S6e
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K06278 CAV1; caveolin 1
K12958 CAV2; caveolin 2
K12959 CAV3; caveolin 3
K06497 CD63; CD63 antigen
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K13375 TGFB1; transforming growth factor beta-1
K10159 TLR2; toll-like receptor 2
K10160 TLR4; toll-like receptor 4
K16865 PDCD4; programmed cell death protein 4
K03156 TNF; tumor necrosis factor superfamily, member 2
K05425 IL12B; interleukin 12B
K05084 ERBB3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K05085 ERBB4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
K04377 MYC; Myc proto-oncogene protein
K02105 CTNNB1; catenin beta 1
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K09108 TFAP4; transcription factor AP-4
K05448 VEGFA; vascular endothelial growth factor A
K05098 KDR; kinase insert domain protein receptor [EC:2.7.10.1]
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K16866 TIMP3; metalloproteinase inhibitor 3
K16857 THBS1; thrombospondin 1
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K08122 LUM; lumican
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K13376 TGFB2; transforming growth factor beta-2
K04500 SMAD2; mothers against decapentaplegic homolog 2
K07964 HPSE; heparanase [EC:3.2.1.166]
K07965 HPSE2; heparanase 2 [EC:3.2.1.-]
K06257 SDC1; syndecan 1
K01348 PLAU; urokinase plasminogen activator [EC:3.4.21.73]
K03985 PLAUR; plasminogen activator, urokinase receptor
K06236 COL1A; collagen type I alpha
K06236 COL1A; collagen type I alpha
K06481 ITGA2; integrin alpha 2
K05719 ITGB1; integrin beta 1
K06251 VTN; vitronectin
K06487 ITGAV; integrin alpha V
K06493 ITGB3; integrin beta 3
K05717 FN1; fibronectin 1
K06588 ITGB5; integrin beta 5
K05460 HGF; hepatocyte growth factor
K03209 WNT1; wingless-type MMTV integration site family, member 1
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K06484 ITGA5; integrin alpha 5
K16336 SDC2; syndecan 2
K08007 EZR; ezrin
K05762 RDX; radixin
K05763 MSN; moesin
K16338 SDC4; syndecan 4
K18497 FGF2; fibroblast growth factor 2
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K12461 FRS2; fibroblast growth factor receptor substrate 2
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K16867 NUDT16L1; NUDT16-like protein 1
K05760 PXN; paxillin
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K08523 HBEGF; heparin-binding EGF-like growth factor
K08107 GPC1; glypican 1
K13769 IGF2; insulin-like growth factor 2
K08109 GPC3; glypican 3
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K11988 SHH; sonic hedgehog
K11989 IHH; indian hedgehog
K06225 PTCH1; patched 1
K06226 SMO; smoothened
K06255 HSPG2; basement membrane-specific heparan sulfate proteoglycan core protein
K01365 CTSL; cathepsin L [EC:3.4.22.15]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K09543 HSPB2; heat shock protein beta-2
K05697 PTPN6; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
|
05204 Chemical carcinogenesis - DNA adducts [PATH:hsa05204]
|
05207 Chemical carcinogenesis - receptor activation [PATH:hsa05207]
|
05208 Chemical carcinogenesis - reactive oxygen species [PATH:hsa05208]
|
57412 AS3MT; arsenite methyltransferase
221357 GSTA5; glutathione S-transferase alpha 5
2939 GSTA2; glutathione S-transferase alpha 2
2941 GSTA4; glutathione S-transferase alpha 4
119391 GSTO2; glutathione S-transferase omega 2
2948 GSTM4; glutathione S-transferase mu 4
2953 GSTT2; glutathione S-transferase theta 2 (gene/pseudogene)
2952 GSTT1; glutathione S-transferase theta 1
2947 GSTM3; glutathione S-transferase mu 3
4257 MGST1; microsomal glutathione S-transferase 1
4259 MGST3; microsomal glutathione S-transferase 3
2944 GSTM1; glutathione S-transferase mu 1
2949 GSTM5; glutathione S-transferase mu 5
4258 MGST2; microsomal glutathione S-transferase 2
2938 GSTA1; glutathione S-transferase alpha 1
2946 GSTM2; glutathione S-transferase mu 2
2940 GSTA3; glutathione S-transferase alpha 3
9446 GSTO1; glutathione S-transferase omega 1
653689 GSTT2B; glutathione S-transferase theta 2B
4535 ND1; NADH dehydrogenase subunit 1
4536 ND2; NADH dehydrogenase subunit 2
4537 ND3; NADH dehydrogenase subunit 3
4538 ND4; NADH dehydrogenase subunit 4
4539 ND4L; NADH dehydrogenase subunit 4L
4540 ND5; NADH dehydrogenase subunit 5
4541 ND6; NADH dehydrogenase subunit 6
4723 NDUFV1; NADH:ubiquinone oxidoreductase core subunit V1
4729 NDUFV2; NADH:ubiquinone oxidoreductase core subunit V2
4731 NDUFV3; NADH:ubiquinone oxidoreductase subunit V3
4694 NDUFA1; NADH:ubiquinone oxidoreductase subunit A1
4695 NDUFA2; NADH:ubiquinone oxidoreductase subunit A2
4696 NDUFA3; NADH:ubiquinone oxidoreductase subunit A3
4697 NDUFA4; NDUFA4 mitochondrial complex associated
56901 NDUFA4L2; NDUFA4 mitochondrial complex associated like 2
4698 NDUFA5; NADH:ubiquinone oxidoreductase subunit A5
4700 NDUFA6; NADH:ubiquinone oxidoreductase subunit A6
4701 NDUFA7; NADH:ubiquinone oxidoreductase subunit A7
4702 NDUFA8; NADH:ubiquinone oxidoreductase subunit A8
4704 NDUFA9; NADH:ubiquinone oxidoreductase subunit A9
4705 NDUFA10; NADH:ubiquinone oxidoreductase subunit A10
4706 NDUFAB1; NADH:ubiquinone oxidoreductase subunit AB1
126328 NDUFA11; NADH:ubiquinone oxidoreductase subunit A11
55967 NDUFA12; NADH:ubiquinone oxidoreductase subunit A12
51079 NDUFA13; NADH:ubiquinone oxidoreductase subunit A13
4707 NDUFB1; NADH:ubiquinone oxidoreductase subunit B1
4708 NDUFB2; NADH:ubiquinone oxidoreductase subunit B2
4709 NDUFB3; NADH:ubiquinone oxidoreductase subunit B3
4710 NDUFB4; NADH:ubiquinone oxidoreductase subunit B4
4711 NDUFB5; NADH:ubiquinone oxidoreductase subunit B5
4712 NDUFB6; NADH:ubiquinone oxidoreductase subunit B6
4713 NDUFB7; NADH:ubiquinone oxidoreductase subunit B7
4714 NDUFB8; NADH:ubiquinone oxidoreductase subunit B8
4715 NDUFB9; NADH:ubiquinone oxidoreductase subunit B9
4716 NDUFB10; NADH:ubiquinone oxidoreductase subunit B10
54539 NDUFB11; NADH:ubiquinone oxidoreductase subunit B11
4719 NDUFS1; NADH:ubiquinone oxidoreductase core subunit S1
4720 NDUFS2; NADH:ubiquinone oxidoreductase core subunit S2
4722 NDUFS3; NADH:ubiquinone oxidoreductase core subunit S3
4724 NDUFS4; NADH:ubiquinone oxidoreductase subunit S4
4725 NDUFS5; NADH:ubiquinone oxidoreductase subunit S5
4726 NDUFS6; NADH:ubiquinone oxidoreductase subunit S6
374291 NDUFS7; NADH:ubiquinone oxidoreductase core subunit S7
4728 NDUFS8; NADH:ubiquinone oxidoreductase core subunit S8
4717 NDUFC1; NADH:ubiquinone oxidoreductase subunit C1
4718 NDUFC2; NADH:ubiquinone oxidoreductase subunit C2
100532726 NDUFC2-KCTD14; NDUFC2-KCTD14 readthrough
6389 SDHA; succinate dehydrogenase complex flavoprotein subunit A
6390 SDHB; succinate dehydrogenase complex iron sulfur subunit B
6391 SDHC; succinate dehydrogenase complex subunit C
6392 SDHD; succinate dehydrogenase complex subunit D
7386 UQCRFS1; ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
4519 CYTB; cytochrome b
1537 CYC1; cytochrome c1
7384 UQCRC1; ubiquinol-cytochrome c reductase core protein 1
7385 UQCRC2; ubiquinol-cytochrome c reductase core protein 2
7388 UQCRH; ubiquinol-cytochrome c reductase hinge protein
440567 UQCRHL; ubiquinol-cytochrome c reductase hinge protein like
7381 UQCRB; ubiquinol-cytochrome c reductase binding protein
27089 UQCRQ; ubiquinol-cytochrome c reductase complex III subunit VII
29796 UQCR10; ubiquinol-cytochrome c reductase, complex III subunit X
10975 UQCR11; ubiquinol-cytochrome c reductase, complex III subunit XI
4514 COX3; cytochrome c oxidase subunit III
4512 COX1; cytochrome c oxidase subunit I
4513 COX2; cytochrome c oxidase subunit II
84701 COX4I2; cytochrome c oxidase subunit 4I2
1327 COX4I1; cytochrome c oxidase subunit 4I1
9377 COX5A; cytochrome c oxidase subunit 5A
1329 COX5B; cytochrome c oxidase subunit 5B
1337 COX6A1; cytochrome c oxidase subunit 6A1
1339 COX6A2; cytochrome c oxidase subunit 6A2
1340 COX6B1; cytochrome c oxidase subunit 6B1
125965 COX6B2; cytochrome c oxidase subunit 6B2
1345 COX6C; cytochrome c oxidase subunit 6C
1346 COX7A1; cytochrome c oxidase subunit 7A1
1347 COX7A2; cytochrome c oxidase subunit 7A2
9167 COX7A2L; cytochrome c oxidase subunit 7A2 like
1349 COX7B; cytochrome c oxidase subunit 7B
170712 COX7B2; cytochrome c oxidase subunit 7B2
1350 COX7C; cytochrome c oxidase subunit 7C
341947 COX8C; cytochrome c oxidase subunit 8C
1351 COX8A; cytochrome c oxidase subunit 8A
498 ATP5F1A; ATP synthase F1 subunit alpha
506 ATP5F1B; ATP synthase F1 subunit beta
509 ATP5F1C; ATP synthase F1 subunit gamma
513 ATP5F1D; ATP synthase F1 subunit delta
514 ATP5F1E; ATP synthase F1 subunit epsilon
4508 ATP6; ATP synthase F0 subunit 6
515 ATP5PB; ATP synthase peripheral stalk-membrane subunit b
516 ATP5MC1; ATP synthase membrane subunit c locus 1
517 ATP5MC2; ATP synthase membrane subunit c locus 2
518 ATP5MC3; ATP synthase membrane subunit c locus 3
10476 ATP5PD; ATP synthase peripheral stalk subunit d
539 ATP5PO; ATP synthase peripheral stalk subunit OSCP
522 ATP5PF; ATP synthase peripheral stalk subunit F6
4509 ATP8; ATP synthase F0 subunit 8
6648 SOD2; superoxide dismutase 2
7416 VDAC1; voltage dependent anion channel 1
7417 VDAC2; voltage dependent anion channel 2
7419 VDAC3; voltage dependent anion channel 3
291 SLC25A4; solute carrier family 25 member 4
292 SLC25A5; solute carrier family 25 member 5
293 SLC25A6; solute carrier family 25 member 6
83447 SLC25A31; solute carrier family 25 member 31
10105 PPIF; peptidylprolyl isomerase F
6647 SOD1; superoxide dismutase 1
847 CAT; catalase
10861 SLC26A1; solute carrier family 26 member 1
1836 SLC26A2; solute carrier family 26 member 2
65010 SLC26A6; solute carrier family 26 member 6
115019 SLC26A9; solute carrier family 26 member 9
1544 CYP1A2; cytochrome P450 family 1 subfamily A member 2
1571 CYP2E1; cytochrome P450 family 2 subfamily E member 1
1572 CYP2F1; cytochrome P450 family 2 subfamily F member 1
1543 CYP1A1; cytochrome P450 family 1 subfamily A member 1
1545 CYP1B1; cytochrome P450 family 1 subfamily B member 1
2052 EPHX1; epoxide hydrolase 1
2053 EPHX2; epoxide hydrolase 2
79852 EPHX3; epoxide hydrolase 3
253152 EPHX4; epoxide hydrolase 4
10327 AKR1A1; aldo-keto reductase family 1 member A1
1645 AKR1C1; aldo-keto reductase family 1 member C1
1646 AKR1C2; aldo-keto reductase family 1 member C2
8644 AKR1C3; aldo-keto reductase family 1 member C3
1109 AKR1C4; aldo-keto reductase family 1 member C4
1728 NQO1; NAD(P)H quinone dehydrogenase 1
873 CBR1; carbonyl reductase 1
196 AHR; aryl hydrocarbon receptor
4025 LPO; lactoperoxidase
50507 NOX4; NADPH oxidase 4
1535 CYBA; cytochrome b-245 alpha chain
27035 NOX1; NADPH oxidase 1
653361 NCF1; neutrophil cytosolic factor 1
4688 NCF2; neutrophil cytosolic factor 2
1950 EGF; epidermal growth factor
1956 EGFR; epidermal growth factor receptor
3082 HGF; hepatocyte growth factor
4233 MET; MET proto-oncogene, receptor tyrosine kinase
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
4217 MAP3K5; mitogen-activated protein kinase kinase kinase 5
6416 MAP2K4; mitogen-activated protein kinase kinase 4
5609 MAP2K7; mitogen-activated protein kinase kinase 7
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
5600 MAPK11; mitogen-activated protein kinase 11
6300 MAPK12; mitogen-activated protein kinase 12
5603 MAPK13; mitogen-activated protein kinase 13
1432 MAPK14; mitogen-activated protein kinase 14
3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
2353 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5879 RAC1; Rac family small GTPase 1
5170 PDPK1; 3-phosphoinositide dependent protein kinase 1
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
2309 FOXO3; forkhead box O3
572 BAD; BCL2 associated agonist of cell death
5770 PTPN1; protein tyrosine phosphatase non-receptor type 1
5728 PTEN; phosphatase and tensin homolog
1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
4792 NFKBIA; NFKB inhibitor alpha
5970 RELA; RELA proto-oncogene, NF-kB subunit
4790 NFKB1; nuclear factor kappa B subunit 1
5580 PRKCD; protein kinase C delta
5795 PTPRJ; protein tyrosine phosphatase receptor type J
52 ACP1; acid phosphatase 1
5781 PTPN11; protein tyrosine phosphatase non-receptor type 11
6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase
25 ABL1; ABL proto-oncogene 1, non-receptor tyrosine kinase
27 ABL2; ABL proto-oncogene 2, non-receptor tyrosine kinase
5587 PRKD1; protein kinase D1
23683 PRKD3; protein kinase D3
25865 PRKD2; protein kinase D2
5747 PTK2; protein tyrosine kinase 2
5337 PLD1; phospholipase D1
5338 PLD2; phospholipase D2
9020 MAP3K14; mitogen-activated protein kinase kinase kinase 14
3091 HIF1A; hypoxia inducible factor 1 subunit alpha
405 ARNT; aryl hydrocarbon receptor nuclear translocator
7422 VEGFA; vascular endothelial growth factor A
9817 KEAP1; kelch like ECH associated protein 1
4780 NFE2L2; NFE2 like bZIP transcription factor 2
3162 HMOX1; heme oxygenase 1
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K07755 AS3MT; arsenite methyltransferase [EC:2.1.1.137]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K03878 ND1; NADH-ubiquinone oxidoreductase chain 1 [EC:7.1.1.2]
K03879 ND2; NADH-ubiquinone oxidoreductase chain 2 [EC:7.1.1.2]
K03880 ND3; NADH-ubiquinone oxidoreductase chain 3 [EC:7.1.1.2]
K03881 ND4; NADH-ubiquinone oxidoreductase chain 4 [EC:7.1.1.2]
K03882 ND4L; NADH-ubiquinone oxidoreductase chain 4L [EC:7.1.1.2]
K03883 ND5; NADH-ubiquinone oxidoreductase chain 5 [EC:7.1.1.2]
K03884 ND6; NADH-ubiquinone oxidoreductase chain 6 [EC:7.1.1.2]
K03942 NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
K03943 NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:7.1.1.2]
K03944 NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
K03945 NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1
K03946 NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2
K03947 NDUFA3; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3
K03948 NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K03948 NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K03949 NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5
K03950 NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6
K03951 NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7
K03952 NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8
K03953 NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9
K03954 NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10
K03955 NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1, acyl-carrier protein
K03956 NDUFA11; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11
K11352 NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12
K11353 NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13
K03957 NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
K03959 NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3
K03960 NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4
K03961 NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5
K03962 NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6
K03963 NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7
K03964 NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8
K03965 NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9
K03966 NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10
K11351 NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
K03934 NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:7.1.1.2]
K03935 NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:7.1.1.2]
K03936 NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:7.1.1.2]
K03937 NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
K03938 NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5
K03939 NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6
K03940 NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:7.1.1.2]
K03941 NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:7.1.1.2]
K03967 NDUFC1; NADH dehydrogenase (ubiquinone) 1 subunit C1
K03968 NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
K03968 NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
K00234 SDHA; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
K00235 SDHB; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
K00236 SDHC; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
K00237 SDHD; succinate dehydrogenase (ubiquinone) membrane anchor subunit
K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
K00413 CYC1; ubiquinol-cytochrome c reductase cytochrome c1 subunit
K00414 QCR1; ubiquinol-cytochrome c reductase core subunit 1
K00415 QCR2; ubiquinol-cytochrome c reductase core subunit 2
K00416 QCR6; ubiquinol-cytochrome c reductase subunit 6
K00416 QCR6; ubiquinol-cytochrome c reductase subunit 6
K00417 QCR7; ubiquinol-cytochrome c reductase subunit 7
K00418 QCR8; ubiquinol-cytochrome c reductase subunit 8
K00419 QCR9; ubiquinol-cytochrome c reductase subunit 9
K00420 QCR10; ubiquinol-cytochrome c reductase subunit 10
K02262 COX3; cytochrome c oxidase subunit 3
K02256 COX1; cytochrome c oxidase subunit 1 [EC:7.1.1.9]
K02261 COX2; cytochrome c oxidase subunit 2
K02263 COX4; cytochrome c oxidase subunit 4
K02263 COX4; cytochrome c oxidase subunit 4
K02264 COX5A; cytochrome c oxidase subunit 5a
K02265 COX5B; cytochrome c oxidase subunit 5b
K02266 COX6A; cytochrome c oxidase subunit 6a
K02266 COX6A; cytochrome c oxidase subunit 6a
K02267 COX6B; cytochrome c oxidase subunit 6b
K02267 COX6B; cytochrome c oxidase subunit 6b
K02268 COX6C; cytochrome c oxidase subunit 6c
K02270 COX7A; cytochrome c oxidase subunit 7a
K02270 COX7A; cytochrome c oxidase subunit 7a
K02270 COX7A; cytochrome c oxidase subunit 7a
K02271 COX7B; cytochrome c oxidase subunit 7b
K02271 COX7B; cytochrome c oxidase subunit 7b
K02272 COX7C; cytochrome c oxidase subunit 7c
K02273 COX8; cytochrome c oxidase subunit 8
K02273 COX8; cytochrome c oxidase subunit 8
K02132 ATPeF1A; F-type H+-transporting ATPase subunit alpha
K02133 ATPeF1B; F-type H+-transporting ATPase subunit beta [EC:7.1.2.2]
K02136 ATPeF1G; F-type H+-transporting ATPase subunit gamma
K02134 ATPeF1D; F-type H+-transporting ATPase subunit delta
K02135 ATPeF1E; F-type H+-transporting ATPase subunit epsilon
K02126 ATPeF0A; F-type H+-transporting ATPase subunit a
K02127 ATPeF0B; F-type H+-transporting ATPase subunit b
K02128 ATPeF0C; F-type H+-transporting ATPase subunit c
K02128 ATPeF0C; F-type H+-transporting ATPase subunit c
K02128 ATPeF0C; F-type H+-transporting ATPase subunit c
K02138 ATPeF0D; F-type H+-transporting ATPase subunit d
K02137 ATPeF0O; F-type H+-transporting ATPase subunit O
K02131 ATPeF0F6; F-type H+-transporting ATPase subunit 6
K02125 ATPeF08; F-type H+-transporting ATPase subunit 8
K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
K04565 SOD1; superoxide dismutase, Cu-Zn family [EC:1.15.1.1]
K03781 katE; catalase [EC:1.11.1.6]
K14700 SLC26A1; solute carrier family 26 (sulfate anion transporter), member 1
K14701 SLC26A2; solute carrier family 26 (sulfate anion transporter), member 2
K14704 SLC26A6; solute carrier family 26 (sulfate anion transporter), member 6
K14706 SLC26A9; solute carrier family 26 (sulfate anion transporter), member 9
K07409 CYP1A2; cytochrome P450 family 1 subfamily A2 [EC:1.14.14.1]
K07415 CYP2E1; cytochrome P450 family 2 subfamily E1 [EC:1.14.14.-]
K07416 CYP2F; cytochrome P450 family 2 subfamily F [EC:1.14.14.1]
K07408 CYP1A1; cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1]
K07410 CYP1B1; cytochrome P450 family 1 subfamily B1 [EC:1.14.14.1]
K01253 EPHX1; microsomal epoxide hydrolase [EC:3.3.2.9]
K08726 EPHX2; soluble epoxide hydrolase / lipid-phosphate phosphatase [EC:3.3.2.10 3.1.3.76]
K22368 EPHX3; epoxide hydrolase 3 [EC:3.3.2.10]
K22369 EPHX4; epoxide hydrolase 4 [EC:3.3.-.-]
K00002 AKR1A1; alcohol dehydrogenase (NADP+) [EC:1.1.1.2]
K00212 AKR1C1; 20alpha/3alpha-hydroxysteroid dehydrogenase / dihydrodiol dehydrogenase [EC:1.1.1.149 1.1.1.357 1.3.1.20]
K00089 AKR1C2; 3alpha-hydroxysteroid 3-dehydrogenase [EC:1.1.1.213 1.1.1.357]
K04119 AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
K00037 AKR1C4; 3alpha-hydroxysteroid 3-dehydrogenase / chlordecone reductase [EC:1.1.1.50 1.1.1.357 1.1.1.225]
K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K00079 CBR1; carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
K09093 AHR; aryl hydrocarbon receptor
K12550 LPO; lactoperoxidase [EC:1.11.1.7]
K21423 NOX4; NADPH oxidase 4 [EC:1.6.3.-]
K08009 CYBA; cytochrome b-245, alpha polypeptide
K08008 NOX1; NADPH oxidase 1
K08011 NCF1; neutrophil cytosolic factor 1
K08010 NCF2; neutrophil cytosolic factor 2
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05460 HGF; hepatocyte growth factor
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K09408 FOXO3; forkhead box protein O3
K02158 BAD; Bcl-2-antagonist of cell death
K05696 PTPN1; tyrosine-protein phosphatase non-receptor type 1 [EC:3.1.3.48]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K05698 PTPRJ; receptor-type tyrosine-protein phosphatase eta [EC:3.1.3.48]
K14394 ACP1; low molecular weight phosphotyrosine protein phosphatase [EC:3.1.3.2 3.1.3.48]
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K08887 ABL2; abelson tyrosine-protein kinase 2 [EC:2.7.10.2]
K06070 PKD; protein kinase D [EC:2.7.11.13]
K06070 PKD; protein kinase D [EC:2.7.11.13]
K06070 PKD; protein kinase D [EC:2.7.11.13]
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K04466 MAP3K14; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K05448 VEGFA; vascular endothelial growth factor A
K10456 KLHL19; kelch-like protein 19
K05638 NFE2L2; nuclear factor erythroid 2-related factor 2
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
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05203 Viral carcinogenesis [PATH:hsa05203]
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05230 Central carbon metabolism in cancer [PATH:hsa05230]
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05231 Choline metabolism in cancer [PATH:hsa05231]
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05235 PD-L1 expression and PD-1 checkpoint pathway in cancer [PATH:hsa05235]
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09162 Cancer: specific types
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05210 Colorectal cancer [PATH:hsa05210]
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2932 GSK3B; glycogen synthase kinase 3 beta
8312 AXIN1; axin 1
8313 AXIN2; axin 2
1499 CTNNB1; catenin beta 1
324 APC; APC regulator of WNT signaling pathway
10297 APC2; APC regulator of WNT signaling pathway 2
6932 TCF7; transcription factor 7
83439 TCF7L1; transcription factor 7 like 1
6934 TCF7L2; transcription factor 7 like 2
51176 LEF1; lymphoid enhancer binding factor 1
332 BIRC5; baculoviral IAP repeat containing 5
4609 MYC; MYC proto-oncogene, bHLH transcription factor
595 CCND1; cyclin D1
3845 KRAS; KRAS proto-oncogene, GTPase
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
572 BAD; BCL2 associated agonist of cell death
842 CASP9; caspase 9
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
2353 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
5900 RALGDS; ral guanine nucleotide dissociation stimulator
5898 RALA; RAS like proto-oncogene A
5899 RALB; RAS like proto-oncogene B
5879 RAC1; Rac family small GTPase 1
5880 RAC2; Rac family small GTPase 2
5881 RAC3; Rac family small GTPase 3
387 RHOA; ras homolog family member A
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
1630 DCC; DCC netrin 1 receptor
836 CASP3; caspase 3
26060 APPL1; adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
7040 TGFB1; transforming growth factor beta 1
7042 TGFB2; transforming growth factor beta 2
7043 TGFB3; transforming growth factor beta 3
7046 TGFBR1; transforming growth factor beta receptor 1
7048 TGFBR2; transforming growth factor beta receptor 2
4087 SMAD2; SMAD family member 2
4088 SMAD3; SMAD family member 3
4089 SMAD4; SMAD family member 4
4292 MLH1; mutL homolog 1
4436 MSH2; mutS homolog 2
4437 MSH3; mutS homolog 3
2956 MSH6; mutS homolog 6
581 BAX; BCL2 associated X, apoptosis regulator
5366 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
10018 BCL2L11; BCL2 like 11
27113 BBC3; BCL2 binding component 3
596 BCL2; BCL2 apoptosis regulator
54205 CYCS; cytochrome c, somatic
7157 TP53; tumor protein p53
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
1647 GADD45A; growth arrest and DNA damage inducible alpha
4616 GADD45B; growth arrest and DNA damage inducible beta
10912 GADD45G; growth arrest and DNA damage inducible gamma
578 BAK1; BCL2 antagonist/killer 1
1643 DDB2; damage specific DNA binding protein 2
51426 POLK; DNA polymerase kappa
1950 EGF; epidermal growth factor
7039 TGFA; transforming growth factor alpha
2069 EREG; epiregulin
374 AREG; amphiregulin
1956 EGFR; epidermal growth factor receptor
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
2475 MTOR; mechanistic target of rapamycin kinase
6198 RPS6KB1; ribosomal protein S6 kinase B1
6199 RPS6KB2; ribosomal protein S6 kinase B2
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K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02105 CTNNB1; catenin beta 1
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K07827 KRAS; GTPase KRas
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04513 RHOA; Ras homolog gene family, member A
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K06765 DCC; deleted in colorectal carcinoma
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K08733 APPL1; DCC-interacting protein 13 alpha
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K08734 MLH1; DNA mismatch repair protein MLH1
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K02159 BAX; apoptosis regulator BAX
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K16341 BCL2L11; Bcl-2-like protein 11
K10132 BBC3; Bcl-2-binding component 3
K02161 BCL2; apoptosis regulator Bcl-2
K08738 CYC; cytochrome c
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K09784 EREG; epiregulin
K09782 AREG; amphiregulin
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07828 NRAS; GTPase NRas
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
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05212 Pancreatic cancer [PATH:hsa05212]
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3845 KRAS; KRAS proto-oncogene, GTPase
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
9459 ARHGEF6; Rac/Cdc42 guanine nucleotide exchange factor 6
5879 RAC1; Rac family small GTPase 1
5880 RAC2; Rac family small GTPase 2
5881 RAC3; Rac family small GTPase 3
4790 NFKB1; nuclear factor kappa B subunit 1
5970 RELA; RELA proto-oncogene, NF-kB subunit
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
572 BAD; BCL2 associated agonist of cell death
598 BCL2L1; BCL2 like 1
842 CASP9; caspase 9
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
5900 RALGDS; ral guanine nucleotide dissociation stimulator
5898 RALA; RAS like proto-oncogene A
5899 RALB; RAS like proto-oncogene B
10928 RALBP1; ralA binding protein 1
998 CDC42; cell division cycle 42
5337 PLD1; phospholipase D1
5338 PLD2; phospholipase D2
7039 TGFA; transforming growth factor alpha
1950 EGF; epidermal growth factor
1956 EGFR; epidermal growth factor receptor
2064 ERBB2; erb-b2 receptor tyrosine kinase 2
2475 MTOR; mechanistic target of rapamycin kinase
6198 RPS6KB1; ribosomal protein S6 kinase B1
6199 RPS6KB2; ribosomal protein S6 kinase B2
3716 JAK1; Janus kinase 1
6774 STAT3; signal transducer and activator of transcription 3
6772 STAT1; signal transducer and activator of transcription 1
7422 VEGFA; vascular endothelial growth factor A
1029 CDKN2A; cyclin dependent kinase inhibitor 2A
1019 CDK4; cyclin dependent kinase 4
1021 CDK6; cyclin dependent kinase 6
595 CCND1; cyclin D1
5925 RB1; RB transcriptional corepressor 1
1869 E2F1; E2F transcription factor 1
1870 E2F2; E2F transcription factor 2
1871 E2F3; E2F transcription factor 3
7157 TP53; tumor protein p53
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
1647 GADD45A; growth arrest and DNA damage inducible alpha
4616 GADD45B; growth arrest and DNA damage inducible beta
10912 GADD45G; growth arrest and DNA damage inducible gamma
581 BAX; BCL2 associated X, apoptosis regulator
578 BAK1; BCL2 antagonist/killer 1
1643 DDB2; damage specific DNA binding protein 2
51426 POLK; DNA polymerase kappa
7040 TGFB1; transforming growth factor beta 1
7042 TGFB2; transforming growth factor beta 2
7043 TGFB3; transforming growth factor beta 3
7046 TGFBR1; transforming growth factor beta receptor 1
7048 TGFBR2; transforming growth factor beta receptor 2
4087 SMAD2; SMAD family member 2
4088 SMAD3; SMAD family member 3
4089 SMAD4; SMAD family member 4
675 BRCA2; BRCA2 DNA repair associated
5888 RAD51; RAD51 recombinase
|
K07827 KRAS; GTPase KRas
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K05729 ARHGEF6; Rho guanine nucleotide exchange factor 6
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K08773 RALBP1; RalA-binding protein 1
K04393 CDC42; cell division control protein 42
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K08774 TGFA; transforming growth factor, alpha
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11220 STAT1; signal transducer and activator of transcription 1
K05448 VEGFA; vascular endothelial growth factor A
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K08775 BRCA2; breast cancer 2 susceptibility protein
K04482 RAD51; DNA repair protein RAD51
|
05225 Hepatocellular carcinoma [PATH:hsa05225]
|
7039 TGFA; transforming growth factor alpha
1956 EGFR; epidermal growth factor receptor
3481 IGF2; insulin like growth factor 2
3480 IGF1R; insulin like growth factor 1 receptor
5335 PLCG1; phospholipase C gamma 1
5336 PLCG2; phospholipase C gamma 2
5578 PRKCA; protein kinase C alpha
5579 PRKCB; protein kinase C beta
5582 PRKCG; protein kinase C gamma
2002 ELK1; ETS transcription factor ELK1
6464 SHC1; SHC adaptor protein 1
25759 SHC2; SHC adaptor protein 2
53358 SHC3; SHC adaptor protein 3
399694 SHC4; SHC adaptor protein 4
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
5728 PTEN; phosphatase and tensin homolog
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
2475 MTOR; mechanistic target of rapamycin kinase
6198 RPS6KB1; ribosomal protein S6 kinase B1
6199 RPS6KB2; ribosomal protein S6 kinase B2
572 BAD; BCL2 associated agonist of cell death
598 BCL2L1; BCL2 like 1
4609 MYC; MYC proto-oncogene, bHLH transcription factor
5925 RB1; RB transcriptional corepressor 1
1869 E2F1; E2F transcription factor 1
1870 E2F2; E2F transcription factor 2
1871 E2F3; E2F transcription factor 3
7015 TERT; telomerase reverse transcriptase
7012 TERC; telomerase RNA component
7157 TP53; tumor protein p53
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
1647 GADD45A; growth arrest and DNA damage inducible alpha
4616 GADD45B; growth arrest and DNA damage inducible beta
10912 GADD45G; growth arrest and DNA damage inducible gamma
581 BAX; BCL2 associated X, apoptosis regulator
578 BAK1; BCL2 antagonist/killer 1
1643 DDB2; damage specific DNA binding protein 2
51426 POLK; DNA polymerase kappa
1029 CDKN2A; cyclin dependent kinase inhibitor 2A
1019 CDK4; cyclin dependent kinase 4
1021 CDK6; cyclin dependent kinase 6
595 CCND1; cyclin D1
7040 TGFB1; transforming growth factor beta 1
7042 TGFB2; transforming growth factor beta 2
7043 TGFB3; transforming growth factor beta 3
7046 TGFBR1; transforming growth factor beta receptor 1
7048 TGFBR2; transforming growth factor beta receptor 2
4087 SMAD2; SMAD family member 2
4088 SMAD3; SMAD family member 3
4089 SMAD4; SMAD family member 4
7471 WNT1; Wnt family member 1
7472 WNT2; Wnt family member 2
7482 WNT2B; Wnt family member 2B
7473 WNT3; Wnt family member 3
89780 WNT3A; Wnt family member 3A
54361 WNT4; Wnt family member 4
7474 WNT5A; Wnt family member 5A
81029 WNT5B; Wnt family member 5B
7475 WNT6; Wnt family member 6
7476 WNT7A; Wnt family member 7A
7477 WNT7B; Wnt family member 7B
7478 WNT8A; Wnt family member 8A
7479 WNT8B; Wnt family member 8B
7483 WNT9A; Wnt family member 9A
7484 WNT9B; Wnt family member 9B
7480 WNT10B; Wnt family member 10B
80326 WNT10A; Wnt family member 10A
7481 WNT11; Wnt family member 11
51384 WNT16; Wnt family member 16
8321 FZD1; frizzled class receptor 1
8324 FZD7; frizzled class receptor 7
2535 FZD2; frizzled class receptor 2
7976 FZD3; frizzled class receptor 3
8322 FZD4; frizzled class receptor 4
7855 FZD5; frizzled class receptor 5
8325 FZD8; frizzled class receptor 8
8323 FZD6; frizzled class receptor 6
11211 FZD10; frizzled class receptor 10
8326 FZD9; frizzled class receptor 9
4041 LRP5; LDL receptor related protein 5
4040 LRP6; LDL receptor related protein 6
1857 DVL3; dishevelled segment polarity protein 3
1856 DVL2; dishevelled segment polarity protein 2
1855 DVL1; dishevelled segment polarity protein 1
10023 FRAT1; FRAT regulator of WNT signaling pathway 1
23401 FRAT2; FRAT regulator of WNT signaling pathway 2
2932 GSK3B; glycogen synthase kinase 3 beta
8312 AXIN1; axin 1
8313 AXIN2; axin 2
324 APC; APC regulator of WNT signaling pathway
10297 APC2; APC regulator of WNT signaling pathway 2
1499 CTNNB1; catenin beta 1
122011 CSNK1A1L; casein kinase 1 alpha 1 like
1452 CSNK1A1; casein kinase 1 alpha 1
6932 TCF7; transcription factor 7
83439 TCF7L1; transcription factor 7 like 1
6934 TCF7L2; transcription factor 7 like 2
51176 LEF1; lymphoid enhancer binding factor 1
9817 KEAP1; kelch like ECH associated protein 1
4780 NFE2L2; NFE2 like bZIP transcription factor 2
3162 HMOX1; heme oxygenase 1
1728 NQO1; NAD(P)H quinone dehydrogenase 1
221357 GSTA5; glutathione S-transferase alpha 5
2939 GSTA2; glutathione S-transferase alpha 2
2941 GSTA4; glutathione S-transferase alpha 4
119391 GSTO2; glutathione S-transferase omega 2
2948 GSTM4; glutathione S-transferase mu 4
2953 GSTT2; glutathione S-transferase theta 2 (gene/pseudogene)
2952 GSTT1; glutathione S-transferase theta 1
2947 GSTM3; glutathione S-transferase mu 3
4257 MGST1; microsomal glutathione S-transferase 1
4259 MGST3; microsomal glutathione S-transferase 3
2944 GSTM1; glutathione S-transferase mu 1
2949 GSTM5; glutathione S-transferase mu 5
4258 MGST2; microsomal glutathione S-transferase 2
2938 GSTA1; glutathione S-transferase alpha 1
2946 GSTM2; glutathione S-transferase mu 2
2940 GSTA3; glutathione S-transferase alpha 3
9446 GSTO1; glutathione S-transferase omega 1
653689 GSTT2B; glutathione S-transferase theta 2B
2950 GSTP1; glutathione S-transferase pi 1
7296 TXNRD1; thioredoxin reductase 1
114112 TXNRD3; thioredoxin reductase 3
10587 TXNRD2; thioredoxin reductase 2
3082 HGF; hepatocyte growth factor
4233 MET; MET proto-oncogene, receptor tyrosine kinase
2549 GAB1; GRB2 associated binding protein 1
71 ACTG1; actin gamma 1
60 ACTB; actin beta
86 ACTL6A; actin like 6A
51412 ACTL6B; actin like 6B
6602 SMARCD1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
6603 SMARCD2; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
6604 SMARCD3; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
55274 PHF10; PHD finger protein 10
8193 DPF1; double PHD fingers 1
8110 DPF3; double PHD fingers 3
57492 ARID1B; AT-rich interaction domain 1B
8289 ARID1A; AT-rich interaction domain 1A
6605 SMARCE1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
6598 SMARCB1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
6599 SMARCC1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1
6601 SMARCC2; SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2
6595 SMARCA2; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
6597 SMARCA4; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
196528 ARID2; AT-rich interaction domain 2
55193 PBRM1; polybromo 1
29117 BRD7; bromodomain containing 7
|
K08774 TGFA; transforming growth factor, alpha
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K13769 IGF2; insulin-like growth factor 2
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04375 ELK1; ETS domain-containing protein Elk-1
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K04377 MYC; Myc proto-oncogene protein
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
K22183 TERC; telomerase RNA component
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K02105 CTNNB1; catenin beta 1
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K10456 KLHL19; kelch-like protein 19
K05638 NFE2L2; nuclear factor erythroid 2-related factor 2
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K05460 HGF; hepatocyte growth factor
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K09593 GAB1; GRB2-associated-binding protein 1
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
K11340 ACTL6A; actin-like protein 6A
K11652 ACTL6B; actin-like protein 6B
K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
K22197 BAF45A; BRG1-associated factor 45A
K22198 BAF45B_C; BRG1-associated factor 45B/C
K22198 BAF45B_C; BRG1-associated factor 45B/C
K11653 ARID1; AT-rich interactive domain-containing protein 1
K11653 ARID1; AT-rich interactive domain-containing protein 1
K11651 SMARCE1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1
K11648 SMARCB1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
K11649 SMARCC; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C
K11649 SMARCC; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C
K11647 SMARCA2_4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:5.6.2.-]
K11647 SMARCA2_4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:5.6.2.-]
K11765 ARID2; AT-rich interactive domain-containing protein 2
K11757 PBRM1; protein polybromo-1
K11723 BRD7; bromodomain-containing protein 7
|
05226 Gastric cancer [PATH:hsa05226]
|
1045 CDX2; caudal type homeobox 2
4583 MUC2; mucin 2, oligomeric mucus/gel-forming
1015 CDH17; cadherin 17
83998 REG4; regenerating family member 4
5243 ABCB1; ATP binding cassette subfamily B member 1
6469 SHH; sonic hedgehog signaling molecule
7157 TP53; tumor protein p53
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
1647 GADD45A; growth arrest and DNA damage inducible alpha
4616 GADD45B; growth arrest and DNA damage inducible beta
10912 GADD45G; growth arrest and DNA damage inducible gamma
581 BAX; BCL2 associated X, apoptosis regulator
578 BAK1; BCL2 antagonist/killer 1
1643 DDB2; damage specific DNA binding protein 2
51426 POLK; DNA polymerase kappa
5915 RARB; retinoic acid receptor beta
6256 RXRA; retinoid X receptor alpha
6257 RXRB; retinoid X receptor beta
6258 RXRG; retinoid X receptor gamma
7471 WNT1; Wnt family member 1
7472 WNT2; Wnt family member 2
7482 WNT2B; Wnt family member 2B
7473 WNT3; Wnt family member 3
89780 WNT3A; Wnt family member 3A
54361 WNT4; Wnt family member 4
7474 WNT5A; Wnt family member 5A
81029 WNT5B; Wnt family member 5B
7475 WNT6; Wnt family member 6
7476 WNT7A; Wnt family member 7A
7477 WNT7B; Wnt family member 7B
7478 WNT8A; Wnt family member 8A
7479 WNT8B; Wnt family member 8B
7483 WNT9A; Wnt family member 9A
7484 WNT9B; Wnt family member 9B
7480 WNT10B; Wnt family member 10B
80326 WNT10A; Wnt family member 10A
7481 WNT11; Wnt family member 11
51384 WNT16; Wnt family member 16
8321 FZD1; frizzled class receptor 1
8324 FZD7; frizzled class receptor 7
2535 FZD2; frizzled class receptor 2
7976 FZD3; frizzled class receptor 3
8322 FZD4; frizzled class receptor 4
7855 FZD5; frizzled class receptor 5
8325 FZD8; frizzled class receptor 8
8323 FZD6; frizzled class receptor 6
11211 FZD10; frizzled class receptor 10
8326 FZD9; frizzled class receptor 9
4041 LRP5; LDL receptor related protein 5
4040 LRP6; LDL receptor related protein 6
1857 DVL3; dishevelled segment polarity protein 3
1856 DVL2; dishevelled segment polarity protein 2
1855 DVL1; dishevelled segment polarity protein 1
10023 FRAT1; FRAT regulator of WNT signaling pathway 1
23401 FRAT2; FRAT regulator of WNT signaling pathway 2
2932 GSK3B; glycogen synthase kinase 3 beta
8312 AXIN1; axin 1
8313 AXIN2; axin 2
324 APC; APC regulator of WNT signaling pathway
10297 APC2; APC regulator of WNT signaling pathway 2
1499 CTNNB1; catenin beta 1
122011 CSNK1A1L; casein kinase 1 alpha 1 like
1452 CSNK1A1; casein kinase 1 alpha 1
6932 TCF7; transcription factor 7
83439 TCF7L1; transcription factor 7 like 1
6934 TCF7L2; transcription factor 7 like 2
51176 LEF1; lymphoid enhancer binding factor 1
4609 MYC; MYC proto-oncogene, bHLH transcription factor
595 CCND1; cyclin D1
7015 TERT; telomerase reverse transcriptase
7012 TERC; telomerase RNA component
1950 EGF; epidermal growth factor
1956 EGFR; epidermal growth factor receptor
2064 ERBB2; erb-b2 receptor tyrosine kinase 2
6464 SHC1; SHC adaptor protein 1
25759 SHC2; SHC adaptor protein 2
53358 SHC3; SHC adaptor protein 3
399694 SHC4; SHC adaptor protein 4
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
2475 MTOR; mechanistic target of rapamycin kinase
6198 RPS6KB1; ribosomal protein S6 kinase B1
6199 RPS6KB2; ribosomal protein S6 kinase B2
596 BCL2; BCL2 apoptosis regulator
4292 MLH1; mutL homolog 1
1027 CDKN1B; cyclin dependent kinase inhibitor 1B
1017 CDK2; cyclin dependent kinase 2
898 CCNE1; cyclin E1
9134 CCNE2; cyclin E2
5925 RB1; RB transcriptional corepressor 1
1869 E2F1; E2F transcription factor 1
1870 E2F2; E2F transcription factor 2
1871 E2F3; E2F transcription factor 3
7040 TGFB1; transforming growth factor beta 1
7042 TGFB2; transforming growth factor beta 2
7043 TGFB3; transforming growth factor beta 3
7046 TGFBR1; transforming growth factor beta receptor 1
7048 TGFBR2; transforming growth factor beta receptor 2
4087 SMAD2; SMAD family member 2
4088 SMAD3; SMAD family member 3
4089 SMAD4; SMAD family member 4
1030 CDKN2B; cyclin dependent kinase inhibitor 2B
999 CDH1; cadherin 1
29119 CTNNA3; catenin alpha 3
1495 CTNNA1; catenin alpha 1
1496 CTNNA2; catenin alpha 2
3728 JUP; junction plakoglobin
3082 HGF; hepatocyte growth factor
4233 MET; MET proto-oncogene, receptor tyrosine kinase
2246 FGF1; fibroblast growth factor 1
2247 FGF2; fibroblast growth factor 2
2248 FGF3; fibroblast growth factor 3
2249 FGF4; fibroblast growth factor 4
8822 FGF17; fibroblast growth factor 17
2251 FGF6; fibroblast growth factor 6
2252 FGF7; fibroblast growth factor 7
2253 FGF8; fibroblast growth factor 8
2254 FGF9; fibroblast growth factor 9
2255 FGF10; fibroblast growth factor 10
8823 FGF16; fibroblast growth factor 16
2250 FGF5; fibroblast growth factor 5
8817 FGF18; fibroblast growth factor 18
26281 FGF20; fibroblast growth factor 20
27006 FGF22; fibroblast growth factor 22
9965 FGF19; fibroblast growth factor 19
26291 FGF21; fibroblast growth factor 21
8074 FGF23; fibroblast growth factor 23
2263 FGFR2; fibroblast growth factor receptor 2
2549 GAB1; GRB2 associated binding protein 1
|
K22234 CDX2; homeobox protein CDX2
K10955 MUC2; mucin-2
K06811 CDH17; cadherin 17, LI cadherin
K22244 REG4; regenerating islet-derived protein 4
K05658 ABCB1; ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:7.6.2.2]
K11988 SHH; sonic hedgehog
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K08528 RARB; retinoic acid receptor beta
K08524 RXRA; retinoid X receptor alpha
K08525 RXRB; retinoid X receptor beta
K08526 RXRG; retinoid X receptor gamma
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K02105 CTNNB1; catenin beta 1
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
K22183 TERC; telomerase RNA component
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02161 BCL2; apoptosis regulator Bcl-2
K08734 MLH1; DNA mismatch repair protein MLH1
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K05689 CDH1; cadherin 1, type 1, E-cadherin
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K10056 JUP; junction plakoglobin
K05460 HGF; hepatocyte growth factor
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K09593 GAB1; GRB2-associated-binding protein 1
|
05214 Glioma [PATH:hsa05214]
|
1950 EGF; epidermal growth factor
7039 TGFA; transforming growth factor alpha
1956 EGFR; epidermal growth factor receptor
5154 PDGFA; platelet derived growth factor subunit A
5155 PDGFB; platelet derived growth factor subunit B
5156 PDGFRA; platelet derived growth factor receptor alpha
5159 PDGFRB; platelet derived growth factor receptor beta
3479 IGF1; insulin like growth factor 1
3480 IGF1R; insulin like growth factor 1 receptor
5335 PLCG1; phospholipase C gamma 1
5336 PLCG2; phospholipase C gamma 2
810 CALML3; calmodulin like 3
805 CALM2; calmodulin 2
808 CALM3; calmodulin 3
801 CALM1; calmodulin 1
163688 CALML6; calmodulin like 6
51806 CALML5; calmodulin like 5
91860 CALML4; calmodulin like 4
57118 CAMK1D; calcium/calmodulin dependent protein kinase ID
57172 CAMK1G; calcium/calmodulin dependent protein kinase IG
8536 CAMK1; calcium/calmodulin dependent protein kinase I
815 CAMK2A; calcium/calmodulin dependent protein kinase II alpha
817 CAMK2D; calcium/calmodulin dependent protein kinase II delta
816 CAMK2B; calcium/calmodulin dependent protein kinase II beta
818 CAMK2G; calcium/calmodulin dependent protein kinase II gamma
814 CAMK4; calcium/calmodulin dependent protein kinase IV
5578 PRKCA; protein kinase C alpha
5579 PRKCB; protein kinase C beta
5582 PRKCG; protein kinase C gamma
6464 SHC1; SHC adaptor protein 1
25759 SHC2; SHC adaptor protein 2
53358 SHC3; SHC adaptor protein 3
399694 SHC4; SHC adaptor protein 4
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
2475 MTOR; mechanistic target of rapamycin kinase
5728 PTEN; phosphatase and tensin homolog
1029 CDKN2A; cyclin dependent kinase inhibitor 2A
4193 MDM2; MDM2 proto-oncogene
7157 TP53; tumor protein p53
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
595 CCND1; cyclin D1
1019 CDK4; cyclin dependent kinase 4
1021 CDK6; cyclin dependent kinase 6
5925 RB1; RB transcriptional corepressor 1
1869 E2F1; E2F transcription factor 1
1870 E2F2; E2F transcription factor 2
1871 E2F3; E2F transcription factor 3
1647 GADD45A; growth arrest and DNA damage inducible alpha
4616 GADD45B; growth arrest and DNA damage inducible beta
10912 GADD45G; growth arrest and DNA damage inducible gamma
581 BAX; BCL2 associated X, apoptosis regulator
578 BAK1; BCL2 antagonist/killer 1
1643 DDB2; damage specific DNA binding protein 2
51426 POLK; DNA polymerase kappa
|
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K08794 CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
K08794 CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
K08794 CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K05869 CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04503 CCND1; G1/S-specific cyclin-D1
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
|
05216 Thyroid cancer [PATH:hsa05216]
|
5979 RET; ret proto-oncogene
8030 CCDC6; coiled-coil domain containing 6
8031 NCOA4; nuclear receptor coactivator 4
4914 NTRK1; neurotrophic receptor tyrosine kinase 1
7170 TPM3; tropomyosin 3
7175 TPR; translocated promoter region, nuclear basket protein
10342 TFG; trafficking from ER to golgi regulator
3265 HRAS; HRas proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
7849 PAX8; paired box 8
5468 PPARG; peroxisome proliferator activated receptor gamma
6256 RXRA; retinoid X receptor alpha
6257 RXRB; retinoid X receptor beta
6258 RXRG; retinoid X receptor gamma
7157 TP53; tumor protein p53
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
1647 GADD45A; growth arrest and DNA damage inducible alpha
4616 GADD45B; growth arrest and DNA damage inducible beta
10912 GADD45G; growth arrest and DNA damage inducible gamma
581 BAX; BCL2 associated X, apoptosis regulator
578 BAK1; BCL2 antagonist/killer 1
1643 DDB2; damage specific DNA binding protein 2
51426 POLK; DNA polymerase kappa
999 CDH1; cadherin 1
1499 CTNNB1; catenin beta 1
6932 TCF7; transcription factor 7
83439 TCF7L1; transcription factor 7 like 1
6934 TCF7L2; transcription factor 7 like 2
51176 LEF1; lymphoid enhancer binding factor 1
4609 MYC; MYC proto-oncogene, bHLH transcription factor
595 CCND1; cyclin D1
|
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K09288 CCDC6; coiled-coil domain-containing protein 6
K09289 NCOA4; nuclear receptor coactivator 4
K03176 NTRK1; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K09290 TPM3; tropomyosin 3
K09291 TPR; nucleoprotein TPR
K09292 TFG; protein TFG
K02833 HRAS; GTPase HRas
K07828 NRAS; GTPase NRas
K07827 KRAS; GTPase KRas
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K09293 PAX8; paired box protein 8
K08530 NR1C3; peroxisome proliferator-activated receptor gamma
K08524 RXRA; retinoid X receptor alpha
K08525 RXRB; retinoid X receptor beta
K08526 RXRG; retinoid X receptor gamma
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K05689 CDH1; cadherin 1, type 1, E-cadherin
K02105 CTNNB1; catenin beta 1
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
|
05221 Acute myeloid leukemia [PATH:hsa05221]
|
3815 KIT; KIT proto-oncogene, receptor tyrosine kinase
2322 FLT3; fms related receptor tyrosine kinase 3
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
4790 NFKB1; nuclear factor kappa B subunit 1
5970 RELA; RELA proto-oncogene, NF-kB subunit
572 BAD; BCL2 associated agonist of cell death
2475 MTOR; mechanistic target of rapamycin kinase
1978 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
6198 RPS6KB1; ribosomal protein S6 kinase B1
6199 RPS6KB2; ribosomal protein S6 kinase B2
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
6774 STAT3; signal transducer and activator of transcription 3
6776 STAT5A; signal transducer and activator of transcription 5A
6777 STAT5B; signal transducer and activator of transcription 5B
5292 PIM1; Pim-1 proto-oncogene, serine/threonine kinase
11040 PIM2; Pim-2 proto-oncogene, serine/threonine kinase
861 RUNX1; RUNX family transcription factor 1
1436 CSF1R; colony stimulating factor 1 receptor
4353 MPO; myeloperoxidase
1437 CSF2; colony stimulating factor 2
3562 IL3; interleukin 3
862 RUNX1T1; RUNX1 partner transcriptional co-repressor 1
5371 PML; PML nuclear body scaffold
5914 RARA; retinoic acid receptor alpha
7704 ZBTB16; zinc finger and BTB domain containing 16
1050 CEBPA; CCAAT enhancer binding protein alpha
8864 PER2; period circadian regulator 2
6688 SPI1; Spi-1 proto-oncogene
929 CD14; CD14 molecule
3684 ITGAM; integrin subunit alpha M
2209 FCGR1A; Fc gamma receptor Ia
1053 CEBPE; CCAAT enhancer binding protein epsilon
597 BCL2A1; BCL2 related protein A1
890 CCNA2; cyclin A2
8900 CCNA1; cyclin A1
4609 MYC; MYC proto-oncogene, bHLH transcription factor
1848 DUSP6; dual specificity phosphatase 6
3728 JUP; junction plakoglobin
6932 TCF7; transcription factor 7
83439 TCF7L1; transcription factor 7 like 1
6934 TCF7L2; transcription factor 7 like 2
51176 LEF1; lymphoid enhancer binding factor 1
595 CCND1; cyclin D1
5467 PPARD; peroxisome proliferator activated receptor delta
|
K05091 KIT; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05092 FLT3; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K02158 BAD; Bcl-2-antagonist of cell death
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07828 NRAS; GTPase NRas
K07827 KRAS; GTPase KRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04692 STAT3; signal transducer and activator of transcription 3
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K08806 PIM2; proto-oncogene serine/threonine-protein kinase Pim-2 [EC:2.7.11.1]
K08367 RUNX1; runt-related transcription factor 1
K05090 CSF1R; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K10789 MPO; myeloperoxidase [EC:1.11.2.2]
K05427 CSF2; granulocyte-macrophage colony-stimulating factor
K04736 IL3; interleukin 3
K10053 RUNX1T1; CBFA2/RNUX1 translocation partner 1
K10054 PML; E3 SUMO-protein ligase PML [EC:2.3.2.-]
K08527 RARA; retinoic acid receptor alpha
K10055 ZBTB16; zinc finger and BTB domain-containing protein 16
K09055 CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
K02633 PER2; period circadian protein 2
K09438 SPI1; transcription factor PU.1
K04391 CD14; monocyte differentiation antigen CD14
K06461 ITGAM; integrin alpha M
K06498 FCGR1A; high affinity immunoglobulin gamma Fc receptor I
K10051 CEBPE; CCAAT/enhancer binding protein (C/EBP), epsilon
K02162 BCL2A1; hematopoietic Bcl-2-related protein A1
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K04377 MYC; Myc proto-oncogene protein
K21946 DUSP6; dual specificity phosphatase 6 [EC:3.1.3.16 3.1.3.48]
K10056 JUP; junction plakoglobin
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04503 CCND1; G1/S-specific cyclin-D1
K04504 NR1C2; peroxisome proliferator-activated receptor delta
|
05220 Chronic myeloid leukemia [PATH:hsa05220]
|
613 BCR; BCR activator of RhoGEF and GTPase
25 ABL1; ABL proto-oncogene 1, non-receptor tyrosine kinase
1398 CRK; CRK proto-oncogene, adaptor protein
1399 CRKL; CRK like proto-oncogene, adaptor protein
867 CBL; Cbl proto-oncogene
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
572 BAD; BCL2 associated agonist of cell death
598 BCL2L1; BCL2 like 1
1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
4792 NFKBIA; NFKB inhibitor alpha
4790 NFKB1; nuclear factor kappa B subunit 1
5970 RELA; RELA proto-oncogene, NF-kB subunit
4193 MDM2; MDM2 proto-oncogene
7157 TP53; tumor protein p53
1027 CDKN1B; cyclin dependent kinase inhibitor 1B
2885 GRB2; growth factor receptor bound protein 2
9846 GAB2; GRB2 associated binding protein 2
5781 PTPN11; protein tyrosine phosphatase non-receptor type 11
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
6464 SHC1; SHC adaptor protein 1
25759 SHC2; SHC adaptor protein 2
53358 SHC3; SHC adaptor protein 3
399694 SHC4; SHC adaptor protein 4
4609 MYC; MYC proto-oncogene, bHLH transcription factor
6776 STAT5A; signal transducer and activator of transcription 5A
6777 STAT5B; signal transducer and activator of transcription 5B
1029 CDKN2A; cyclin dependent kinase inhibitor 2A
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
595 CCND1; cyclin D1
1019 CDK4; cyclin dependent kinase 4
1021 CDK6; cyclin dependent kinase 6
5925 RB1; RB transcriptional corepressor 1
1869 E2F1; E2F transcription factor 1
1870 E2F2; E2F transcription factor 2
1871 E2F3; E2F transcription factor 3
1647 GADD45A; growth arrest and DNA damage inducible alpha
4616 GADD45B; growth arrest and DNA damage inducible beta
10912 GADD45G; growth arrest and DNA damage inducible gamma
581 BAX; BCL2 associated X, apoptosis regulator
578 BAK1; BCL2 antagonist/killer 1
1643 DDB2; damage specific DNA binding protein 2
51426 POLK; DNA polymerase kappa
7040 TGFB1; transforming growth factor beta 1
7042 TGFB2; transforming growth factor beta 2
7043 TGFB3; transforming growth factor beta 3
7046 TGFBR1; transforming growth factor beta receptor 1
7048 TGFBR2; transforming growth factor beta receptor 2
4088 SMAD3; SMAD family member 3
4089 SMAD4; SMAD family member 4
2122 MECOM; MDS1 and EVI1 complex locus
861 RUNX1; RUNX family transcription factor 1
1487 CTBP1; C-terminal binding protein 1
1488 CTBP2; C-terminal binding protein 2
3065 HDAC1; histone deacetylase 1
3066 HDAC2; histone deacetylase 2
|
K08878 BCR1; breakpoint cluster region protein [EC:2.7.11.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K04364 GRB2; growth factor receptor-bound protein 2
K08091 GAB2; GRB2-associated-binding protein 2
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04377 MYC; Myc proto-oncogene protein
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04503 CCND1; G1/S-specific cyclin-D1
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04462 MECOM; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
K08367 RUNX1; runt-related transcription factor 1
K04496 CTBP; C-terminal binding protein [EC:1.1.1.428]
K04496 CTBP; C-terminal binding protein [EC:1.1.1.428]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
|
05217 Basal cell carcinoma [PATH:hsa05217]
|
05218 Melanoma [PATH:hsa05218]
|
2246 FGF1; fibroblast growth factor 1
2247 FGF2; fibroblast growth factor 2
2248 FGF3; fibroblast growth factor 3
2249 FGF4; fibroblast growth factor 4
8822 FGF17; fibroblast growth factor 17
2251 FGF6; fibroblast growth factor 6
2252 FGF7; fibroblast growth factor 7
2253 FGF8; fibroblast growth factor 8
2254 FGF9; fibroblast growth factor 9
2255 FGF10; fibroblast growth factor 10
8823 FGF16; fibroblast growth factor 16
2250 FGF5; fibroblast growth factor 5
8817 FGF18; fibroblast growth factor 18
26281 FGF20; fibroblast growth factor 20
27006 FGF22; fibroblast growth factor 22
9965 FGF19; fibroblast growth factor 19
26291 FGF21; fibroblast growth factor 21
8074 FGF23; fibroblast growth factor 23
3082 HGF; hepatocyte growth factor
3479 IGF1; insulin like growth factor 1
5154 PDGFA; platelet derived growth factor subunit A
5155 PDGFB; platelet derived growth factor subunit B
56034 PDGFC; platelet derived growth factor C
80310 PDGFD; platelet derived growth factor D
1950 EGF; epidermal growth factor
2260 FGFR1; fibroblast growth factor receptor 1
4233 MET; MET proto-oncogene, receptor tyrosine kinase
3480 IGF1R; insulin like growth factor 1 receptor
5156 PDGFRA; platelet derived growth factor receptor alpha
5159 PDGFRB; platelet derived growth factor receptor beta
1956 EGFR; epidermal growth factor receptor
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
595 CCND1; cyclin D1
1019 CDK4; cyclin dependent kinase 4
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
572 BAD; BCL2 associated agonist of cell death
5728 PTEN; phosphatase and tensin homolog
1029 CDKN2A; cyclin dependent kinase inhibitor 2A
4193 MDM2; MDM2 proto-oncogene
7157 TP53; tumor protein p53
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
1021 CDK6; cyclin dependent kinase 6
5925 RB1; RB transcriptional corepressor 1
1869 E2F1; E2F transcription factor 1
1870 E2F2; E2F transcription factor 2
1871 E2F3; E2F transcription factor 3
999 CDH1; cadherin 1
1647 GADD45A; growth arrest and DNA damage inducible alpha
4616 GADD45B; growth arrest and DNA damage inducible beta
10912 GADD45G; growth arrest and DNA damage inducible gamma
581 BAX; BCL2 associated X, apoptosis regulator
578 BAK1; BCL2 antagonist/killer 1
1643 DDB2; damage specific DNA binding protein 2
51426 POLK; DNA polymerase kappa
4286 MITF; melanocyte inducing transcription factor
|
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K05460 HGF; hepatocyte growth factor
K05459 IGF1; insulin-like growth factor 1
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05450 PDGFC_D; platelet derived growth factor C/D
K04357 EGF; epidermal growth factor
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04503 CCND1; G1/S-specific cyclin-D1
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K05689 CDH1; cadherin 1, type 1, E-cadherin
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K09455 MITF; microphthalmia-associated transcription factor
|
05211 Renal cell carcinoma [PATH:hsa05211]
|
3091 HIF1A; hypoxia inducible factor 1 subunit alpha
2034 EPAS1; endothelial PAS domain protein 1
54583 EGLN1; egl-9 family hypoxia inducible factor 1
112399 EGLN3; egl-9 family hypoxia inducible factor 3
112398 EGLN2; egl-9 family hypoxia inducible factor 2
7428 VHL; von Hippel-Lindau tumor suppressor
6921 ELOC; elongin C
6923 ELOB; elongin B
9978 RBX1; ring-box 1
8453 CUL2; cullin 2
405 ARNT; aryl hydrocarbon receptor nuclear translocator
9915 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
1387 CREBBP; CREB binding protein
2033 EP300; E1A binding protein p300
6513 SLC2A1; solute carrier family 2 member 1
7422 VEGFA; vascular endothelial growth factor A
7040 TGFB1; transforming growth factor beta 1
7042 TGFB2; transforming growth factor beta 2
7043 TGFB3; transforming growth factor beta 3
5155 PDGFB; platelet derived growth factor subunit B
7039 TGFA; transforming growth factor alpha
3082 HGF; hepatocyte growth factor
4233 MET; MET proto-oncogene, receptor tyrosine kinase
2549 GAB1; GRB2 associated binding protein 1
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
572 BAD; BCL2 associated agonist of cell death
1398 CRK; CRK proto-oncogene, adaptor protein
1399 CRKL; CRK like proto-oncogene, adaptor protein
2889 RAPGEF1; Rap guanine nucleotide exchange factor 1
5906 RAP1A; RAP1A, member of RAS oncogene family
5908 RAP1B; RAP1B, member of RAS oncogene family
5781 PTPN11; protein tyrosine phosphatase non-receptor type 11
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
2113 ETS1; ETS proto-oncogene 1, transcription factor
3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
5879 RAC1; Rac family small GTPase 1
998 CDC42; cell division cycle 42
5058 PAK1; p21 (RAC1) activated kinase 1
5062 PAK2; p21 (RAC1) activated kinase 2
5063 PAK3; p21 (RAC1) activated kinase 3
10298 PAK4; p21 (RAC1) activated kinase 4
57144 PAK5; p21 (RAC1) activated kinase 5
56924 PAK6; p21 (RAC1) activated kinase 6
106821730 BUB1B-PAK6; BUB1B-PAK6 readthrough
5546 PRCC; proline rich mitotic checkpoint control factor
7030 TFE3; transcription factor binding to IGHM enhancer 3
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
2271 FH; fumarate hydratase
201163 FLCN; folliculin
|
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K09095 HIF2A; hypoxia-inducible factor 2 alpha
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K03871 VHL; von Hippel-Lindau disease tumor supressor
K03872 ELOC; elongin-C
K03873 ELOB; elongin-B
K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K03870 CUL2; cullin 2
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K15589 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K07299 SLC2A1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K05448 VEGFA; vascular endothelial growth factor A
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K17386 PDGFB; platelet-derived growth factor subunit B
K08774 TGFA; transforming growth factor, alpha
K05460 HGF; hepatocyte growth factor
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K09593 GAB1; GRB2-associated-binding protein 1
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K06277 RAPGEF1; Rap guanine nucleotide exchange factor 1
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K02678 ETS1; C-ets-1
K04448 JUN; transcription factor AP-1
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K04393 CDC42; cell division control protein 42
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K13105 PRCC; proline-rich protein PRCC
K09105 TFE3; transcription factor E3
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
K09594 FLCN; folliculin
|
05219 Bladder cancer [PATH:hsa05219]
|
2261 FGFR3; fibroblast growth factor receptor 3
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
9252 RPS6KA5; ribosomal protein S6 kinase A5
4609 MYC; MYC proto-oncogene, bHLH transcription factor
11186 RASSF1; Ras association domain family member 1
1612 DAPK1; death associated protein kinase 1
1613 DAPK3; death associated protein kinase 3
23604 DAPK2; death associated protein kinase 2
1029 CDKN2A; cyclin dependent kinase inhibitor 2A
4193 MDM2; MDM2 proto-oncogene
7157 TP53; tumor protein p53
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
595 CCND1; cyclin D1
1019 CDK4; cyclin dependent kinase 4
5925 RB1; RB transcriptional corepressor 1
1869 E2F1; E2F transcription factor 1
1870 E2F2; E2F transcription factor 2
1871 E2F3; E2F transcription factor 3
7057 THBS1; thrombospondin 1
1839 HBEGF; heparin binding EGF like growth factor
4313 MMP2; matrix metallopeptidase 2
4318 MMP9; matrix metallopeptidase 9
7380 UPK3A; uroplakin 3A
6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase
1950 EGF; epidermal growth factor
2064 ERBB2; erb-b2 receptor tyrosine kinase 2
1956 EGFR; epidermal growth factor receptor
1890 TYMP; thymidine phosphorylase
7422 VEGFA; vascular endothelial growth factor A
4312 MMP1; matrix metallopeptidase 1
3576 CXCL8; C-X-C motif chemokine ligand 8
999 CDH1; cadherin 1
|
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K04377 MYC; Myc proto-oncogene protein
K09850 RASSF1; Ras association domain-containing protein 1
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04503 CCND1; G1/S-specific cyclin-D1
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K16857 THBS1; thrombospondin 1
K08523 HBEGF; heparin-binding EGF-like growth factor
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K19520 UPK3A; uroplakin-3a
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K04357 EGF; epidermal growth factor
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K00758 deoA; thymidine phosphorylase [EC:2.4.2.4]
K05448 VEGFA; vascular endothelial growth factor A
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K10030 IL8; interleukin 8
K05689 CDH1; cadherin 1, type 1, E-cadherin
|
05215 Prostate cancer [PATH:hsa05215]
|
2950 GSTP1; glutathione S-transferase pi 1
1027 CDKN1B; cyclin dependent kinase inhibitor 1B
1017 CDK2; cyclin dependent kinase 2
898 CCNE1; cyclin E1
9134 CCNE2; cyclin E2
5925 RB1; RB transcriptional corepressor 1
1869 E2F1; E2F transcription factor 1
1870 E2F2; E2F transcription factor 2
1871 E2F3; E2F transcription factor 3
7113 TMPRSS2; transmembrane serine protease 2
2078 ERG; ETS transcription factor ERG
5328 PLAU; plasminogen activator, urokinase
5327 PLAT; plasminogen activator, tissue type
4314 MMP3; matrix metallopeptidase 3
4318 MMP9; matrix metallopeptidase 9
6935 ZEB1; zinc finger E-box binding homeobox 1
7850 IL1R2; interleukin 1 receptor type 2
6692 SPINT1; serine peptidase inhibitor, Kunitz type 1
2119 ETV5; ETS variant transcription factor 5
3630 INS; insulin
5154 PDGFA; platelet derived growth factor subunit A
5155 PDGFB; platelet derived growth factor subunit B
56034 PDGFC; platelet derived growth factor C
80310 PDGFD; platelet derived growth factor D
1950 EGF; epidermal growth factor
7039 TGFA; transforming growth factor alpha
3479 IGF1; insulin like growth factor 1
3645 INSRR; insulin receptor related receptor
5156 PDGFRA; platelet derived growth factor receptor alpha
5159 PDGFRB; platelet derived growth factor receptor beta
2260 FGFR1; fibroblast growth factor receptor 1
2263 FGFR2; fibroblast growth factor receptor 2
1956 EGFR; epidermal growth factor receptor
2064 ERBB2; erb-b2 receptor tyrosine kinase 2
3480 IGF1R; insulin like growth factor 1 receptor
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
5728 PTEN; phosphatase and tensin homolog
5170 PDPK1; 3-phosphoinositide dependent protein kinase 1
4824 NKX3-1; NK3 homeobox 1
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
842 CASP9; caspase 9
572 BAD; BCL2 associated agonist of cell death
2308 FOXO1; forkhead box O1
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
4193 MDM2; MDM2 proto-oncogene
7157 TP53; tumor protein p53
2932 GSK3B; glycogen synthase kinase 3 beta
1385 CREB1; cAMP responsive element binding protein 1
468 ATF4; activating transcription factor 4
10488 CREB3; cAMP responsive element binding protein 3
90993 CREB3L1; cAMP responsive element binding protein 3 like 1
64764 CREB3L2; cAMP responsive element binding protein 3 like 2
84699 CREB3L3; cAMP responsive element binding protein 3 like 3
148327 CREB3L4; cAMP responsive element binding protein 3 like 4
9586 CREB5; cAMP responsive element binding protein 5
1499 CTNNB1; catenin beta 1
1387 CREBBP; CREB binding protein
2033 EP300; E1A binding protein p300
6932 TCF7; transcription factor 7
83439 TCF7L1; transcription factor 7 like 1
6934 TCF7L2; transcription factor 7 like 2
51176 LEF1; lymphoid enhancer binding factor 1
595 CCND1; cyclin D1
1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
4792 NFKBIA; NFKB inhibitor alpha
4790 NFKB1; nuclear factor kappa B subunit 1
5970 RELA; RELA proto-oncogene, NF-kB subunit
596 BCL2; BCL2 apoptosis regulator
2475 MTOR; mechanistic target of rapamycin kinase
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
6716 SRD5A2; steroid 5 alpha-reductase 2
367 AR; androgen receptor
3320 HSP90AA1; heat shock protein 90 alpha family class A member 1
3326 HSP90AB1; heat shock protein 90 alpha family class B member 1
7184 HSP90B1; heat shock protein 90 beta family member 1
354 KLK3; kallikrein related peptidase 3
|
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K09633 TMPRSS2; transmembrane protease serine 2 [EC:3.4.21.122]
K09435 ERG; transcriptional regulator ERG
K01348 PLAU; urokinase plasminogen activator [EC:3.4.21.73]
K01343 PLAT; tissue plasminogen activator [EC:3.4.21.68]
K01394 MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K09299 ZEB1; zinc finger homeobox protein 1
K04387 IL1R2; interleukin 1 receptor type II
K15619 SPINT1; Kunitz-type protease inhibitor 1
K15593 ETV5; ets translocation variant 5
K04526 INS; insulin
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05450 PDGFC_D; platelet derived growth factor C/D
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K05459 IGF1; insulin-like growth factor 1
K05086 INSRR; insulin receptor-related receptor [EC:2.7.10.1]
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K09348 NKX3-1; homeobox protein Nkx-3.1
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02158 BAD; Bcl-2-antagonist of cell death
K07201 FOXO1; forkhead box protein O1
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5; cyclic AMP-responsive element-binding protein 5
K02105 CTNNB1; catenin beta 1
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04503 CCND1; G1/S-specific cyclin-D1
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K02161 BCL2; apoptosis regulator Bcl-2
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K12344 SRD5A2; 3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:1.3.1.22]
K08557 AR; androgen receptor
K04079 HSP90A; molecular chaperone HtpG
K04079 HSP90A; molecular chaperone HtpG
K09487 HSP90B; heat shock protein 90kDa beta
K01351 KLK3; semenogelase [EC:3.4.21.77]
|
05213 Endometrial cancer [PATH:hsa05213]
|
1950 EGF; epidermal growth factor
1956 EGFR; epidermal growth factor receptor
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
5728 PTEN; phosphatase and tensin homolog
5170 PDPK1; 3-phosphoinositide dependent protein kinase 1
3611 ILK; integrin linked kinase
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
842 CASP9; caspase 9
572 BAD; BCL2 associated agonist of cell death
2309 FOXO3; forkhead box O3
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
2002 ELK1; ETS transcription factor ELK1
4292 MLH1; mutL homolog 1
999 CDH1; cadherin 1
1499 CTNNB1; catenin beta 1
29119 CTNNA3; catenin alpha 3
1495 CTNNA1; catenin alpha 1
1496 CTNNA2; catenin alpha 2
8312 AXIN1; axin 1
8313 AXIN2; axin 2
324 APC; APC regulator of WNT signaling pathway
10297 APC2; APC regulator of WNT signaling pathway 2
2932 GSK3B; glycogen synthase kinase 3 beta
6932 TCF7; transcription factor 7
83439 TCF7L1; transcription factor 7 like 1
6934 TCF7L2; transcription factor 7 like 2
51176 LEF1; lymphoid enhancer binding factor 1
4609 MYC; MYC proto-oncogene, bHLH transcription factor
595 CCND1; cyclin D1
7157 TP53; tumor protein p53
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
1647 GADD45A; growth arrest and DNA damage inducible alpha
4616 GADD45B; growth arrest and DNA damage inducible beta
10912 GADD45G; growth arrest and DNA damage inducible gamma
581 BAX; BCL2 associated X, apoptosis regulator
578 BAK1; BCL2 antagonist/killer 1
1643 DDB2; damage specific DNA binding protein 2
51426 POLK; DNA polymerase kappa
2064 ERBB2; erb-b2 receptor tyrosine kinase 2
|
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K06272 ILK; integrin-linked kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02158 BAD; Bcl-2-antagonist of cell death
K09408 FOXO3; forkhead box protein O3
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04375 ELK1; ETS domain-containing protein Elk-1
K08734 MLH1; DNA mismatch repair protein MLH1
K05689 CDH1; cadherin 1, type 1, E-cadherin
K02105 CTNNB1; catenin beta 1
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
|
05224 Breast cancer [PATH:hsa05224]
|
2099 ESR1; estrogen receptor 1
2100 ESR2; estrogen receptor 2
8648 NCOA1; nuclear receptor coactivator 1
8202 NCOA3; nuclear receptor coactivator 3
2353 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
6667 SP1; Sp1 transcription factor
595 CCND1; cyclin D1
4609 MYC; MYC proto-oncogene, bHLH transcription factor
5241 PGR; progesterone receptor
7471 WNT1; Wnt family member 1
54361 WNT4; Wnt family member 4
8600 TNFSF11; TNF superfamily member 11
2064 ERBB2; erb-b2 receptor tyrosine kinase 2
2246 FGF1; fibroblast growth factor 1
2247 FGF2; fibroblast growth factor 2
2248 FGF3; fibroblast growth factor 3
2249 FGF4; fibroblast growth factor 4
8822 FGF17; fibroblast growth factor 17
2251 FGF6; fibroblast growth factor 6
2252 FGF7; fibroblast growth factor 7
2253 FGF8; fibroblast growth factor 8
2254 FGF9; fibroblast growth factor 9
2255 FGF10; fibroblast growth factor 10
8823 FGF16; fibroblast growth factor 16
2250 FGF5; fibroblast growth factor 5
8817 FGF18; fibroblast growth factor 18
26281 FGF20; fibroblast growth factor 20
27006 FGF22; fibroblast growth factor 22
9965 FGF19; fibroblast growth factor 19
26291 FGF21; fibroblast growth factor 21
8074 FGF23; fibroblast growth factor 23
2260 FGFR1; fibroblast growth factor receptor 1
3479 IGF1; insulin like growth factor 1
3480 IGF1R; insulin like growth factor 1 receptor
1950 EGF; epidermal growth factor
1956 EGFR; epidermal growth factor receptor
3815 KIT; KIT proto-oncogene, receptor tyrosine kinase
6464 SHC1; SHC adaptor protein 1
25759 SHC2; SHC adaptor protein 2
53358 SHC3; SHC adaptor protein 3
399694 SHC4; SHC adaptor protein 4
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
5728 PTEN; phosphatase and tensin homolog
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
2475 MTOR; mechanistic target of rapamycin kinase
6198 RPS6KB1; ribosomal protein S6 kinase B1
6199 RPS6KB2; ribosomal protein S6 kinase B2
182 JAG1; jagged canonical Notch ligand 1
3714 JAG2; jagged canonical Notch ligand 2
10683 DLL3; delta like canonical Notch ligand 3
28514 DLL1; delta like canonical Notch ligand 1
54567 DLL4; delta like canonical Notch ligand 4
4851 NOTCH1; notch receptor 1
4853 NOTCH2; notch receptor 2
4854 NOTCH3; notch receptor 3
4855 NOTCH4; notch receptor 4
3280 HES1; hes family bHLH transcription factor 1
388585 HES5; hes family bHLH transcription factor 5
26508 HEYL; hes related family bHLH transcription factor with YRPW motif like
23462 HEY1; hes related family bHLH transcription factor with YRPW motif 1
23493 HEY2; hes related family bHLH transcription factor with YRPW motif 2
2324 FLT4; fms related receptor tyrosine kinase 4
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
4791 NFKB2; nuclear factor kappa B subunit 2
7472 WNT2; Wnt family member 2
7482 WNT2B; Wnt family member 2B
7473 WNT3; Wnt family member 3
89780 WNT3A; Wnt family member 3A
7474 WNT5A; Wnt family member 5A
81029 WNT5B; Wnt family member 5B
7475 WNT6; Wnt family member 6
7476 WNT7A; Wnt family member 7A
7477 WNT7B; Wnt family member 7B
7478 WNT8A; Wnt family member 8A
7479 WNT8B; Wnt family member 8B
7483 WNT9A; Wnt family member 9A
7484 WNT9B; Wnt family member 9B
7480 WNT10B; Wnt family member 10B
80326 WNT10A; Wnt family member 10A
7481 WNT11; Wnt family member 11
51384 WNT16; Wnt family member 16
8321 FZD1; frizzled class receptor 1
8324 FZD7; frizzled class receptor 7
2535 FZD2; frizzled class receptor 2
7976 FZD3; frizzled class receptor 3
8322 FZD4; frizzled class receptor 4
7855 FZD5; frizzled class receptor 5
8325 FZD8; frizzled class receptor 8
8323 FZD6; frizzled class receptor 6
11211 FZD10; frizzled class receptor 10
8326 FZD9; frizzled class receptor 9
4041 LRP5; LDL receptor related protein 5
4040 LRP6; LDL receptor related protein 6
1857 DVL3; dishevelled segment polarity protein 3
1856 DVL2; dishevelled segment polarity protein 2
1855 DVL1; dishevelled segment polarity protein 1
10023 FRAT1; FRAT regulator of WNT signaling pathway 1
23401 FRAT2; FRAT regulator of WNT signaling pathway 2
2932 GSK3B; glycogen synthase kinase 3 beta
8312 AXIN1; axin 1
8313 AXIN2; axin 2
324 APC; APC regulator of WNT signaling pathway
10297 APC2; APC regulator of WNT signaling pathway 2
1499 CTNNB1; catenin beta 1
122011 CSNK1A1L; casein kinase 1 alpha 1 like
1452 CSNK1A1; casein kinase 1 alpha 1
6932 TCF7; transcription factor 7
83439 TCF7L1; transcription factor 7 like 1
6934 TCF7L2; transcription factor 7 like 2
51176 LEF1; lymphoid enhancer binding factor 1
7157 TP53; tumor protein p53
1647 GADD45A; growth arrest and DNA damage inducible alpha
4616 GADD45B; growth arrest and DNA damage inducible beta
10912 GADD45G; growth arrest and DNA damage inducible gamma
581 BAX; BCL2 associated X, apoptosis regulator
578 BAK1; BCL2 antagonist/killer 1
1643 DDB2; damage specific DNA binding protein 2
51426 POLK; DNA polymerase kappa
1019 CDK4; cyclin dependent kinase 4
1021 CDK6; cyclin dependent kinase 6
5925 RB1; RB transcriptional corepressor 1
1869 E2F1; E2F transcription factor 1
1870 E2F2; E2F transcription factor 2
1871 E2F3; E2F transcription factor 3
672 BRCA1; BRCA1 DNA repair associated
675 BRCA2; BRCA2 DNA repair associated
|
K08550 ESR1; estrogen receptor alpha
K08551 ESR2; estrogen receptor beta
K09101 NCOA1; nuclear receptor coactivator 1 [EC:2.3.1.48]
K11256 NCOA3; nuclear receptor coactivator 3 [EC:2.3.1.48]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K04684 SP1; transcription factor Sp1
K04503 CCND1; G1/S-specific cyclin-D1
K04377 MYC; Myc proto-oncogene protein
K08556 PGR; progesterone receptor
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00408 WNT4; wingless-type MMTV integration site family, member 4
K05473 TNFSF11; tumor necrosis factor ligand superfamily member 11
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05091 KIT; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K06052 JAG1; jagged-1
K21635 JAG2; jagged-2
K06051 DLL; delta
K06051 DLL; delta
K06051 DLL; delta
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K06054 HES1; hairy and enhancer of split 1
K06055 HES5; hairy and enhancer of split 5
K09091 HEY; hairy and enhancer of split related with YRPW motif
K09091 HEY; hairy and enhancer of split related with YRPW motif
K09091 HEY; hairy and enhancer of split related with YRPW motif
K05097 FLT4; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K02105 CTNNB1; catenin beta 1
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04451 TP53; tumor protein p53
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K08775 BRCA2; breast cancer 2 susceptibility protein
|
05222 Small cell lung cancer [PATH:hsa05222]
|
05223 Non-small cell lung cancer [PATH:hsa05223]
|
2272 FHIT; fragile histidine triad diadenosine triphosphatase
5915 RARB; retinoic acid receptor beta
6256 RXRA; retinoid X receptor alpha
6257 RXRB; retinoid X receptor beta
6258 RXRG; retinoid X receptor gamma
1029 CDKN2A; cyclin dependent kinase inhibitor 2A
1019 CDK4; cyclin dependent kinase 4
1021 CDK6; cyclin dependent kinase 6
595 CCND1; cyclin D1
5925 RB1; RB transcriptional corepressor 1
1869 E2F1; E2F transcription factor 1
1870 E2F2; E2F transcription factor 2
1871 E2F3; E2F transcription factor 3
3845 KRAS; KRAS proto-oncogene, GTPase
11186 RASSF1; Ras association domain family member 1
83593 RASSF5; Ras association domain family member 5
6789 STK4; serine/threonine kinase 4
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
5170 PDPK1; 3-phosphoinositide dependent protein kinase 1
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
572 BAD; BCL2 associated agonist of cell death
842 CASP9; caspase 9
2309 FOXO3; forkhead box O3
1950 EGF; epidermal growth factor
7039 TGFA; transforming growth factor alpha
1956 EGFR; epidermal growth factor receptor
2064 ERBB2; erb-b2 receptor tyrosine kinase 2
3082 HGF; hepatocyte growth factor
4233 MET; MET proto-oncogene, receptor tyrosine kinase
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
5335 PLCG1; phospholipase C gamma 1
5336 PLCG2; phospholipase C gamma 2
5578 PRKCA; protein kinase C alpha
5579 PRKCB; protein kinase C beta
5582 PRKCG; protein kinase C gamma
7157 TP53; tumor protein p53
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
1647 GADD45A; growth arrest and DNA damage inducible alpha
4616 GADD45B; growth arrest and DNA damage inducible beta
10912 GADD45G; growth arrest and DNA damage inducible gamma
581 BAX; BCL2 associated X, apoptosis regulator
578 BAK1; BCL2 antagonist/killer 1
1643 DDB2; damage specific DNA binding protein 2
51426 POLK; DNA polymerase kappa
3798 KIF5A; kinesin family member 5A
3799 KIF5B; kinesin family member 5B
3800 KIF5C; kinesin family member 5C
5979 RET; ret proto-oncogene
27436 EML4; EMAP like 4
238 ALK; ALK receptor tyrosine kinase
3718 JAK3; Janus kinase 3
6774 STAT3; signal transducer and activator of transcription 3
6776 STAT5A; signal transducer and activator of transcription 5A
6777 STAT5B; signal transducer and activator of transcription 5B
|
K01522 FHIT; bis(5'-adenosyl)-triphosphatase [EC:3.6.1.29]
K08528 RARB; retinoic acid receptor beta
K08524 RXRA; retinoid X receptor alpha
K08525 RXRB; retinoid X receptor beta
K08526 RXRG; retinoid X receptor gamma
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K07827 KRAS; GTPase KRas
K09850 RASSF1; Ras association domain-containing protein 1
K08015 RASSF5; Ras association domain-containing protein 5
K04411 STK4; serine/threonine kinase 4
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K09408 FOXO3; forkhead box protein O3
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05460 HGF; hepatocyte growth factor
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K10396 KIF5; kinesin family member 5
K10396 KIF5; kinesin family member 5
K10396 KIF5; kinesin family member 5
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K15420 EML4; echinoderm microtubule-associated protein-like 4
K05119 ALK; anaplastic lymphoma kinase [EC:2.7.10.1]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
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09172 Infectious disease: viral
|
05166 Human T-cell leukemia virus 1 infection [PATH:hsa05166]
|
05170 Human immunodeficiency virus 1 infection [PATH:hsa05170]
|
05161 Hepatitis B [PATH:hsa05161]
|
3339 HSPG2; heparan sulfate proteoglycan 2
6554 SLC10A1; solute carrier family 10 member 1
7040 TGFB1; transforming growth factor beta 1
7042 TGFB2; transforming growth factor beta 2
7043 TGFB3; transforming growth factor beta 3
7046 TGFBR1; transforming growth factor beta receptor 1
7048 TGFBR2; transforming growth factor beta receptor 2
4088 SMAD3; SMAD family member 3
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
4609 MYC; MYC proto-oncogene, bHLH transcription factor
1959 EGR2; early growth response 2
1960 EGR3; early growth response 3
1387 CREBBP; CREB binding protein
2033 EP300; E1A binding protein p300
356 FASLG; Fas ligand
1642 DDB1; damage specific DNA binding protein 1
1643 DDB2; damage specific DNA binding protein 2
4214 MAP3K1; mitogen-activated protein kinase kinase kinase 1
7534 YWHAZ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
7529 YWHAB; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
10971 YWHAQ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
6416 MAP2K4; mitogen-activated protein kinase kinase 4
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
4792 NFKBIA; NFKB inhibitor alpha
4790 NFKB1; nuclear factor kappa B subunit 1
5970 RELA; RELA proto-oncogene, NF-kB subunit
4318 MMP9; matrix metallopeptidase 9
596 BCL2; BCL2 apoptosis regulator
572 BAD; BCL2 associated agonist of cell death
355 FAS; Fas cell surface death receptor
8772 FADD; Fas associated via death domain
841 CASP8; caspase 8
843 CASP10; caspase 10
637 BID; BH3 interacting domain death agonist
581 BAX; BCL2 associated X, apoptosis regulator
317 APAF1; apoptotic peptidase activating factor 1
54205 CYCS; cytochrome c, somatic
842 CASP9; caspase 9
836 CASP3; caspase 3
100506742 CASP12; caspase 12 (gene/pseudogene)
332 BIRC5; baculoviral IAP repeat containing 5
7157 TP53; tumor protein p53
890 CCNA2; cyclin A2
8900 CCNA1; cyclin A1
1017 CDK2; cyclin dependent kinase 2
898 CCNE1; cyclin E1
9134 CCNE2; cyclin E2
5925 RB1; RB transcriptional corepressor 1
1869 E2F1; E2F transcription factor 1
1870 E2F2; E2F transcription factor 2
1871 E2F3; E2F transcription factor 3
537 ATP6AP1; ATPase H+ transporting accessory protein 1
5578 PRKCA; protein kinase C alpha
5579 PRKCB; protein kinase C beta
5582 PRKCG; protein kinase C gamma
4772 NFATC1; nuclear factor of activated T cells 1
4773 NFATC2; nuclear factor of activated T cells 2
4775 NFATC3; nuclear factor of activated T cells 3
4776 NFATC4; nuclear factor of activated T cells 4
7124 TNF; tumor necrosis factor
3716 JAK1; Janus kinase 1
3717 JAK2; Janus kinase 2
3718 JAK3; Janus kinase 3
7297 TYK2; tyrosine kinase 2
6774 STAT3; signal transducer and activator of transcription 3
6772 STAT1; signal transducer and activator of transcription 1
6773 STAT2; signal transducer and activator of transcription 2
6775 STAT4; signal transducer and activator of transcription 4
6776 STAT5A; signal transducer and activator of transcription 5A
6777 STAT5B; signal transducer and activator of transcription 5B
6778 STAT6; signal transducer and activator of transcription 6
7419 VDAC3; voltage dependent anion channel 3
2185 PTK2B; protein tyrosine kinase 2 beta
6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
4089 SMAD4; SMAD family member 4
1386 ATF2; activating transcription factor 2
1385 CREB1; cAMP responsive element binding protein 1
10488 CREB3; cAMP responsive element binding protein 3
90993 CREB3L1; cAMP responsive element binding protein 3 like 1
64764 CREB3L2; cAMP responsive element binding protein 3 like 2
84699 CREB3L3; cAMP responsive element binding protein 3 like 3
148327 CREB3L4; cAMP responsive element binding protein 3 like 4
468 ATF4; activating transcription factor 4
9586 CREB5; cAMP responsive element binding protein 5
1388 ATF6B; activating transcription factor 6 beta
3576 CXCL8; C-X-C motif chemokine ligand 8
5111 PCNA; proliferating cell nuclear antigen
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
2353 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
2002 ELK1; ETS transcription factor ELK1
7097 TLR2; toll like receptor 2
4615 MYD88; MYD88 innate immune signal transduction adaptor
114609 TIRAP; TIR domain containing adaptor protein
7099 TLR4; toll like receptor 4
51135 IRAK4; interleukin 1 receptor associated kinase 4
3654 IRAK1; interleukin 1 receptor associated kinase 1
7189 TRAF6; TNF receptor associated factor 6
10454 TAB1; TGF-beta activated kinase 1 (MAP3K7) binding protein 1
23118 TAB2; TGF-beta activated kinase 1 (MAP3K7) binding protein 2
6885 MAP3K7; mitogen-activated protein kinase kinase kinase 7
3569 IL6; interleukin 6
5606 MAP2K3; mitogen-activated protein kinase kinase 3
5608 MAP2K6; mitogen-activated protein kinase kinase 6
5600 MAPK11; mitogen-activated protein kinase 11
6300 MAPK12; mitogen-activated protein kinase 12
5603 MAPK13; mitogen-activated protein kinase 13
1432 MAPK14; mitogen-activated protein kinase 14
5609 MAP2K7; mitogen-activated protein kinase kinase 7
353376 TICAM2; TIR domain containing adaptor molecule 2
7098 TLR3; toll like receptor 3
148022 TICAM1; TIR domain containing adaptor molecule 1
23586 RIGI; RNA sensor RIG-I
64135 IFIH1; interferon induced with helicase C domain 1
57506 MAVS; mitochondrial antiviral signaling protein
7187 TRAF3; TNF receptor associated factor 3
9641 IKBKE; inhibitor of nuclear factor kappa B kinase subunit epsilon
29110 TBK1; TANK binding kinase 1
1654 DDX3X; DEAD-box helicase 3 X-linked
3661 IRF3; interferon regulatory factor 3
3665 IRF7; interferon regulatory factor 7
3439 IFNA1; interferon alpha 1
3440 IFNA2; interferon alpha 2
3441 IFNA4; interferon alpha 4
3442 IFNA5; interferon alpha 5
3443 IFNA6; interferon alpha 6
3444 IFNA7; interferon alpha 7
3445 IFNA8; interferon alpha 8
3446 IFNA10; interferon alpha 10
3447 IFNA13; interferon alpha 13
3448 IFNA14; interferon alpha 14
3449 IFNA16; interferon alpha 16
3451 IFNA17; interferon alpha 17
3452 IFNA21; interferon alpha 21
3456 IFNB1; interferon beta 1
3454 IFNAR1; interferon alpha and beta receptor subunit 1
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K06255 HSPG2; basement membrane-specific heparan sulfate proteoglycan core protein
K14341 SLC10A1; solute carrier family 10 (sodium/bile acid cotransporter), member 1
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K23605 SMAD3; mothers against decapentaplegic homolog 3
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04377 MYC; Myc proto-oncogene protein
K12496 EGR2; early growth response protein 2
K12497 EGR3; early growth response protein 3
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K10610 DDB1; DNA damage-binding protein 1
K10140 DDB2; DNA damage-binding protein 2
K04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K02161 BCL2; apoptosis regulator Bcl-2
K02158 BAD; Bcl-2-antagonist of cell death
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04400 CASP10; caspase 10 [EC:3.4.22.63]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K02084 APAF1; apoptotic protease-activating factor
K08738 CYC; cytochrome c
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04741 CASP12; caspase 12 [EC:3.4.22.-]
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04451 TP53; tumor protein p53
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K03662 ATPeVS1; V-type H+-transporting ATPase S1 subunit
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04446 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4; nuclear factor of activated T-cells, cytoplasmic 4
K03156 TNF; tumor necrosis factor superfamily, member 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K11222 STAT4; signal transducer and activator of transcription 4
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K11225 STAT6; signal transducer and activator of transcription 6
K15041 VDAC3; voltage-dependent anion channel protein 3
K05871 PTK2B; focal adhesion kinase 2 [EC:2.7.10.2]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04448 JUN; transcription factor AP-1
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04450 ATF2; cyclic AMP-dependent transcription factor ATF-2
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
K09047 CREB5; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B; cyclic AMP-dependent transcription factor ATF-6 beta
K10030 IL8; interleukin 8
K04802 PCNA; proliferating cell nuclear antigen
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04375 ELK1; ETS domain-containing protein Elk-1
K10159 TLR2; toll-like receptor 2
K04729 MYD88; myeloid differentiation primary response protein MyD88
K05403 TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
K10160 TLR4; toll-like receptor 4
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04403 MAP3K7IP1; TAK1-binding protein 1
K04404 MAP3K7IP2; TAK1-binding protein 2
K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K05405 IL6; interleukin 6
K04432 MAP2K3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K05409 TIRP; TRIF-related adaptor molecule
K05401 TLR3; toll-like receptor 3
K05842 TRIF; toll-like receptor adapter molecule 1
K12646 RIGI; ATP-dependent RNA helicase DDX58 [EC:5.6.2.6]
K12647 IFIH1; interferon-induced helicase C domain-containing protein 1 [EC:5.6.2.6]
K12648 MAVS; mitochondrial antiviral-signaling protein
K03174 TRAF3; TNF receptor-associated factor 3
K07211 IKBKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
K05411 IRF3; interferon regulatory factor 3
K09447 IRF7; interferon regulatory factor 7
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05130 IFNAR1; interferon receptor 1
|
05160 Hepatitis C [PATH:hsa05160]
|
3949 LDLR; low density lipoprotein receptor
949 SCARB1; scavenger receptor class B member 1
975 CD81; CD81 molecule
1364 CLDN4; claudin 4
1365 CLDN3; claudin 3
1366 CLDN7; claudin 7
149461 CLDN19; claudin 19
10686 CLDN16; claudin 16
23562 CLDN14; claudin 14
24146 CLDN15; claudin 15
26285 CLDN17; claudin 17
49861 CLDN20; claudin 20
5010 CLDN11; claudin 11
51208 CLDN18; claudin 18
53842 CLDN22; claudin 22
7122 CLDN5; claudin 5
9071 CLDN10; claudin 10
9073 CLDN8; claudin 8
9074 CLDN6; claudin 6
9075 CLDN2; claudin 2
9076 CLDN1; claudin 1
9080 CLDN9; claudin 9
137075 CLDN23; claudin 23
100288814 CLDN34; claudin 34
644672 CLDN25; claudin 25
100132463 CLDN24; claudin 24
9069 CLDN12; claudin 12
100506658 OCLN; occludin
4938 OAS1; 2'-5'-oligoadenylate synthetase 1
4939 OAS2; 2'-5'-oligoadenylate synthetase 2
4940 OAS3; 2'-5'-oligoadenylate synthetase 3
6041 RNASEL; ribonuclease L
23586 RIGI; RNA sensor RIG-I
57506 MAVS; mitochondrial antiviral signaling protein
7187 TRAF3; TNF receptor associated factor 3
29110 TBK1; TANK binding kinase 1
9641 IKBKE; inhibitor of nuclear factor kappa B kinase subunit epsilon
3661 IRF3; interferon regulatory factor 3
3665 IRF7; interferon regulatory factor 7
3439 IFNA1; interferon alpha 1
3440 IFNA2; interferon alpha 2
3441 IFNA4; interferon alpha 4
3442 IFNA5; interferon alpha 5
3443 IFNA6; interferon alpha 6
3444 IFNA7; interferon alpha 7
3445 IFNA8; interferon alpha 8
3446 IFNA10; interferon alpha 10
3447 IFNA13; interferon alpha 13
3448 IFNA14; interferon alpha 14
3449 IFNA16; interferon alpha 16
3451 IFNA17; interferon alpha 17
3452 IFNA21; interferon alpha 21
3456 IFNB1; interferon beta 1
3458 IFNG; interferon gamma
7098 TLR3; toll like receptor 3
148022 TICAM1; TIR domain containing adaptor molecule 1
7189 TRAF6; TNF receptor associated factor 6
8737 RIPK1; receptor interacting serine/threonine kinase 1
1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
4792 NFKBIA; NFKB inhibitor alpha
4790 NFKB1; nuclear factor kappa B subunit 1
5970 RELA; RELA proto-oncogene, NF-kB subunit
7124 TNF; tumor necrosis factor
3627 CXCL10; C-X-C motif chemokine ligand 10
27102 EIF2AK1; eukaryotic translation initiation factor 2 alpha kinase 1
5610 EIF2AK2; eukaryotic translation initiation factor 2 alpha kinase 2
9451 EIF2AK3; eukaryotic translation initiation factor 2 alpha kinase 3
440275 EIF2AK4; eukaryotic translation initiation factor 2 alpha kinase 4
3434 IFIT1; interferon induced protein with tetratricopeptide repeats 1
439996 IFIT1B; interferon induced protein with tetratricopeptide repeats 1B
3646 EIF3E; eukaryotic translation initiation factor 3 subunit E
1965 EIF2S1; eukaryotic translation initiation factor 2 subunit alpha
6774 STAT3; signal transducer and activator of transcription 3
9021 SOCS3; suppressor of cytokine signaling 3
3454 IFNAR1; interferon alpha and beta receptor subunit 1
3455 IFNAR2; interferon alpha and beta receptor subunit 2
3716 JAK1; Janus kinase 1
7297 TYK2; tyrosine kinase 2
6772 STAT1; signal transducer and activator of transcription 1
6773 STAT2; signal transducer and activator of transcription 2
10379 IRF9; interferon regulatory factor 9
4599 MX1; MX dynamin like GTPase 1
4600 MX2; MX dynamin like GTPase 2
91543 RSAD2; radical S-adenosyl methionine domain containing 2
5519 PPP2R1B; protein phosphatase 2 scaffold subunit Abeta
5518 PPP2R1A; protein phosphatase 2 scaffold subunit Aalpha
5520 PPP2R2A; protein phosphatase 2 regulatory subunit Balpha
5521 PPP2R2B; protein phosphatase 2 regulatory subunit Bbeta
5522 PPP2R2C; protein phosphatase 2 regulatory subunit Bgamma
55844 PPP2R2D; protein phosphatase 2 regulatory subunit Bdelta
5515 PPP2CA; protein phosphatase 2 catalytic subunit alpha
5516 PPP2CB; protein phosphatase 2 catalytic subunit beta
8554 PIAS1; protein inhibitor of activated STAT 1
1950 EGF; epidermal growth factor
1956 EGFR; epidermal growth factor receptor
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
7534 YWHAZ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
7529 YWHAB; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
10971 YWHAQ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
7531 YWHAE; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
7533 YWHAH; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
7532 YWHAG; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
2932 GSK3B; glycogen synthase kinase 3 beta
1499 CTNNB1; catenin beta 1
572 BAD; BCL2 associated agonist of cell death
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
7157 TP53; tumor protein p53
1017 CDK2; cyclin dependent kinase 2
1019 CDK4; cyclin dependent kinase 4
1021 CDK6; cyclin dependent kinase 6
5925 RB1; RB transcriptional corepressor 1
1869 E2F1; E2F transcription factor 1
1870 E2F2; E2F transcription factor 2
1871 E2F3; E2F transcription factor 3
7132 TNFRSF1A; TNF receptor superfamily member 1A
8717 TRADD; TNFRSF1A associated via death domain
7186 TRAF2; TNF receptor associated factor 2
356 FASLG; Fas ligand
355 FAS; Fas cell surface death receptor
8772 FADD; Fas associated via death domain
841 CASP8; caspase 8
836 CASP3; caspase 3
8837 CFLAR; CASP8 and FADD like apoptosis regulator
637 BID; BH3 interacting domain death agonist
581 BAX; BCL2 associated X, apoptosis regulator
578 BAK1; BCL2 antagonist/killer 1
54205 CYCS; cytochrome c, somatic
317 APAF1; apoptotic peptidase activating factor 1
842 CASP9; caspase 9
10197 PSME3; proteasome activator subunit 3
6256 RXRA; retinoid X receptor alpha
5465 PPARA; peroxisome proliferator activated receptor alpha
10062 NR1H3; nuclear receptor subfamily 1 group H member 3
595 CCND1; cyclin D1
4609 MYC; MYC proto-oncogene, bHLH transcription factor
|
K12473 LDLR; low-density lipoprotein receptor
K13885 SCARB1; scavenger receptor class B, member 1
K06508 CD81; CD81 antigen
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06088 OCLN; occludin
K14216 OAS; 2'-5'-oligoadenylate synthetase [EC:2.7.7.84]
K14216 OAS; 2'-5'-oligoadenylate synthetase [EC:2.7.7.84]
K14216 OAS; 2'-5'-oligoadenylate synthetase [EC:2.7.7.84]
K01165 RNASEL; ribonuclease L
K12646 RIGI; ATP-dependent RNA helicase DDX58 [EC:5.6.2.6]
K12648 MAVS; mitochondrial antiviral-signaling protein
K03174 TRAF3; TNF receptor-associated factor 3
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K07211 IKBKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05411 IRF3; interferon regulatory factor 3
K09447 IRF7; interferon regulatory factor 7
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K04687 IFNG; interferon gamma
K05401 TLR3; toll-like receptor 3
K05842 TRIF; toll-like receptor adapter molecule 1
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K02861 RIPK1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K03156 TNF; tumor necrosis factor superfamily, member 2
K12671 CXCL10; C-X-C motif chemokine 10
K16194 EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1 [EC:2.7.11.1]
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
K08860 EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K16196 EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]
K14217 IFIT1; interferon-induced protein with tetratricopeptide repeats 1
K14217 IFIT1; interferon-induced protein with tetratricopeptide repeats 1
K03250 EIF3E; translation initiation factor 3 subunit E
K03237 EIF2S1; translation initiation factor 2 subunit 1
K04692 STAT3; signal transducer and activator of transcription 3
K04696 SOCS3; suppressor of cytokine signaling 3
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04693 IRF9; interferon regulatory factor 9
K14754 MX; interferon-induced GTP-binding protein Mx
K14754 MX; interferon-induced GTP-binding protein Mx
K15045 RSAD2; radical S-adenosyl methionine domain-containing protein 2
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K06630 YWHAE; 14-3-3 protein epsilon
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02105 CTNNB1; catenin beta 1
K02158 BAD; Bcl-2-antagonist of cell death
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04451 TP53; tumor protein p53
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K03158 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04724 CFLAR; CASP8 and FADD-like apoptosis regulator
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K06698 PSME3; proteasome activator subunit 3 (PA28 gamma)
K08524 RXRA; retinoid X receptor alpha
K07294 NR1C1; peroxisome proliferator-activated receptor alpha
K08536 NR1H3; liver X receptor alpha
K04503 CCND1; G1/S-specific cyclin-D1
K04377 MYC; Myc proto-oncogene protein
|
05171 Coronavirus disease - COVID-19 [PATH:hsa05171]
|
05164 Influenza A [PATH:hsa05164]
|
05162 Measles [PATH:hsa05162]
|
05168 Herpes simplex virus 1 infection [PATH:hsa05168]
|
05163 Human cytomegalovirus infection [PATH:hsa05163]
|
05167 Kaposi sarcoma-associated herpesvirus infection [PATH:hsa05167]
|
05169 Epstein-Barr virus infection [PATH:hsa05169]
|
05165 Human papillomavirus infection [PATH:hsa05165]
|
|
|
09171 Infectious disease: bacterial
|
|
|
09174 Infectious disease: parasitic
|
|
|
09163 Immune disease
|
|
|
09164 Neurodegenerative disease
|
05010 Alzheimer disease [PATH:hsa05010]
|
102 ADAM10; ADAM metallopeptidase domain 10
6868 ADAM17; ADAM metallopeptidase domain 17
351 APP; amyloid beta precursor protein
8883 NAE1; NEDD8 activating enzyme E1 subunit 1
322 APBB1; amyloid beta precursor protein binding family B member 1
2597 GAPDH; glyceraldehyde-3-phosphate dehydrogenase
23621 BACE1; beta-secretase 1
25825 BACE2; beta-secretase 2
10313 RTN3; reticulon 3
57142 RTN4; reticulon 4
55851 PSENEN; presenilin enhancer, gamma-secretase subunit
5663 PSEN1; presenilin 1
5664 PSEN2; presenilin 2
23385 NCSTN; nicastrin
51107 APH1A; aph-1 homolog A, gamma-secretase subunit
83464 APH1B; aph-1 homolog B, gamma-secretase subunit
3416 IDE; insulin degrading enzyme
4311 MME; membrane metalloendopeptidase
4137 MAPT; microtubule associated protein tau
4535 ND1; NADH dehydrogenase subunit 1
4536 ND2; NADH dehydrogenase subunit 2
4537 ND3; NADH dehydrogenase subunit 3
4538 ND4; NADH dehydrogenase subunit 4
4539 ND4L; NADH dehydrogenase subunit 4L
4540 ND5; NADH dehydrogenase subunit 5
4541 ND6; NADH dehydrogenase subunit 6
4723 NDUFV1; NADH:ubiquinone oxidoreductase core subunit V1
4729 NDUFV2; NADH:ubiquinone oxidoreductase core subunit V2
4731 NDUFV3; NADH:ubiquinone oxidoreductase subunit V3
4694 NDUFA1; NADH:ubiquinone oxidoreductase subunit A1
4695 NDUFA2; NADH:ubiquinone oxidoreductase subunit A2
4696 NDUFA3; NADH:ubiquinone oxidoreductase subunit A3
4697 NDUFA4; NDUFA4 mitochondrial complex associated
56901 NDUFA4L2; NDUFA4 mitochondrial complex associated like 2
4698 NDUFA5; NADH:ubiquinone oxidoreductase subunit A5
4700 NDUFA6; NADH:ubiquinone oxidoreductase subunit A6
4701 NDUFA7; NADH:ubiquinone oxidoreductase subunit A7
4702 NDUFA8; NADH:ubiquinone oxidoreductase subunit A8
4704 NDUFA9; NADH:ubiquinone oxidoreductase subunit A9
4705 NDUFA10; NADH:ubiquinone oxidoreductase subunit A10
4706 NDUFAB1; NADH:ubiquinone oxidoreductase subunit AB1
126328 NDUFA11; NADH:ubiquinone oxidoreductase subunit A11
55967 NDUFA12; NADH:ubiquinone oxidoreductase subunit A12
51079 NDUFA13; NADH:ubiquinone oxidoreductase subunit A13
4707 NDUFB1; NADH:ubiquinone oxidoreductase subunit B1
4708 NDUFB2; NADH:ubiquinone oxidoreductase subunit B2
4709 NDUFB3; NADH:ubiquinone oxidoreductase subunit B3
4710 NDUFB4; NADH:ubiquinone oxidoreductase subunit B4
4711 NDUFB5; NADH:ubiquinone oxidoreductase subunit B5
4712 NDUFB6; NADH:ubiquinone oxidoreductase subunit B6
4713 NDUFB7; NADH:ubiquinone oxidoreductase subunit B7
4714 NDUFB8; NADH:ubiquinone oxidoreductase subunit B8
4715 NDUFB9; NADH:ubiquinone oxidoreductase subunit B9
4716 NDUFB10; NADH:ubiquinone oxidoreductase subunit B10
54539 NDUFB11; NADH:ubiquinone oxidoreductase subunit B11
4719 NDUFS1; NADH:ubiquinone oxidoreductase core subunit S1
4720 NDUFS2; NADH:ubiquinone oxidoreductase core subunit S2
4722 NDUFS3; NADH:ubiquinone oxidoreductase core subunit S3
4724 NDUFS4; NADH:ubiquinone oxidoreductase subunit S4
4725 NDUFS5; NADH:ubiquinone oxidoreductase subunit S5
4726 NDUFS6; NADH:ubiquinone oxidoreductase subunit S6
374291 NDUFS7; NADH:ubiquinone oxidoreductase core subunit S7
4728 NDUFS8; NADH:ubiquinone oxidoreductase core subunit S8
4717 NDUFC1; NADH:ubiquinone oxidoreductase subunit C1
4718 NDUFC2; NADH:ubiquinone oxidoreductase subunit C2
100532726 NDUFC2-KCTD14; NDUFC2-KCTD14 readthrough
6389 SDHA; succinate dehydrogenase complex flavoprotein subunit A
6390 SDHB; succinate dehydrogenase complex iron sulfur subunit B
6391 SDHC; succinate dehydrogenase complex subunit C
6392 SDHD; succinate dehydrogenase complex subunit D
7386 UQCRFS1; ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
4519 CYTB; cytochrome b
1537 CYC1; cytochrome c1
7384 UQCRC1; ubiquinol-cytochrome c reductase core protein 1
7385 UQCRC2; ubiquinol-cytochrome c reductase core protein 2
7388 UQCRH; ubiquinol-cytochrome c reductase hinge protein
440567 UQCRHL; ubiquinol-cytochrome c reductase hinge protein like
7381 UQCRB; ubiquinol-cytochrome c reductase binding protein
27089 UQCRQ; ubiquinol-cytochrome c reductase complex III subunit VII
29796 UQCR10; ubiquinol-cytochrome c reductase, complex III subunit X
10975 UQCR11; ubiquinol-cytochrome c reductase, complex III subunit XI
4514 COX3; cytochrome c oxidase subunit III
4512 COX1; cytochrome c oxidase subunit I
4513 COX2; cytochrome c oxidase subunit II
84701 COX4I2; cytochrome c oxidase subunit 4I2
1327 COX4I1; cytochrome c oxidase subunit 4I1
9377 COX5A; cytochrome c oxidase subunit 5A
1329 COX5B; cytochrome c oxidase subunit 5B
1337 COX6A1; cytochrome c oxidase subunit 6A1
1339 COX6A2; cytochrome c oxidase subunit 6A2
1340 COX6B1; cytochrome c oxidase subunit 6B1
125965 COX6B2; cytochrome c oxidase subunit 6B2
1345 COX6C; cytochrome c oxidase subunit 6C
1346 COX7A1; cytochrome c oxidase subunit 7A1
1347 COX7A2; cytochrome c oxidase subunit 7A2
9167 COX7A2L; cytochrome c oxidase subunit 7A2 like
1349 COX7B; cytochrome c oxidase subunit 7B
170712 COX7B2; cytochrome c oxidase subunit 7B2
1350 COX7C; cytochrome c oxidase subunit 7C
341947 COX8C; cytochrome c oxidase subunit 8C
1351 COX8A; cytochrome c oxidase subunit 8A
498 ATP5F1A; ATP synthase F1 subunit alpha
506 ATP5F1B; ATP synthase F1 subunit beta
509 ATP5F1C; ATP synthase F1 subunit gamma
513 ATP5F1D; ATP synthase F1 subunit delta
514 ATP5F1E; ATP synthase F1 subunit epsilon
4508 ATP6; ATP synthase F0 subunit 6
515 ATP5PB; ATP synthase peripheral stalk-membrane subunit b
516 ATP5MC1; ATP synthase membrane subunit c locus 1
517 ATP5MC2; ATP synthase membrane subunit c locus 2
518 ATP5MC3; ATP synthase membrane subunit c locus 3
10476 ATP5PD; ATP synthase peripheral stalk subunit d
539 ATP5PO; ATP synthase peripheral stalk subunit OSCP
522 ATP5PF; ATP synthase peripheral stalk subunit F6
4509 ATP8; ATP synthase F0 subunit 8
3028 HSD17B10; hydroxysteroid 17-beta dehydrogenase 10
5481 PPID; peptidylprolyl isomerase D
7416 VDAC1; voltage dependent anion channel 1
7417 VDAC2; voltage dependent anion channel 2
7419 VDAC3; voltage dependent anion channel 3
291 SLC25A4; solute carrier family 25 member 4
292 SLC25A5; solute carrier family 25 member 5
293 SLC25A6; solute carrier family 25 member 6
83447 SLC25A31; solute carrier family 25 member 31
10105 PPIF; peptidylprolyl isomerase F
4023 LPL; lipoprotein lipase
348 APOE; apolipoprotein E
4035 LRP1; LDL receptor related protein 1
355 FAS; Fas cell surface death receptor
7132 TNFRSF1A; TNF receptor superfamily member 1A
8772 FADD; Fas associated via death domain
841 CASP8; caspase 8
637 BID; BH3 interacting domain death agonist
810 CALML3; calmodulin like 3
805 CALM2; calmodulin 2
808 CALM3; calmodulin 3
801 CALM1; calmodulin 1
163688 CALML6; calmodulin like 6
51806 CALML5; calmodulin like 5
91860 CALML4; calmodulin like 4
5530 PPP3CA; protein phosphatase 3 catalytic subunit alpha
5532 PPP3CB; protein phosphatase 3 catalytic subunit beta
5533 PPP3CC; protein phosphatase 3 catalytic subunit gamma
5534 PPP3R1; protein phosphatase 3 regulatory subunit B, alpha
5535 PPP3R2; protein phosphatase 3 regulatory subunit B, beta
572 BAD; BCL2 associated agonist of cell death
54205 CYCS; cytochrome c, somatic
317 APAF1; apoptotic peptidase activating factor 1
842 CASP9; caspase 9
836 CASP3; caspase 3
1128 CHRM1; cholinergic receptor muscarinic 1
1131 CHRM3; cholinergic receptor muscarinic 3
1133 CHRM5; cholinergic receptor muscarinic 5
2915 GRM5; glutamate metabotropic receptor 5
2776 GNAQ; G protein subunit alpha q
23236 PLCB1; phospholipase C beta 1
5330 PLCB2; phospholipase C beta 2
5331 PLCB3; phospholipase C beta 3
5332 PLCB4; phospholipase C beta 4
2902 GRIN1; glutamate ionotropic receptor NMDA type subunit 1
2903 GRIN2A; glutamate ionotropic receptor NMDA type subunit 2A
2904 GRIN2B; glutamate ionotropic receptor NMDA type subunit 2B
2905 GRIN2C; glutamate ionotropic receptor NMDA type subunit 2C
2906 GRIN2D; glutamate ionotropic receptor NMDA type subunit 2D
775 CACNA1C; calcium voltage-gated channel subunit alpha1 C
776 CACNA1D; calcium voltage-gated channel subunit alpha1 D
778 CACNA1F; calcium voltage-gated channel subunit alpha1 F
779 CACNA1S; calcium voltage-gated channel subunit alpha1 S
1139 CHRNA7; cholinergic receptor nicotinic alpha 7 subunit
90550 MCU; mitochondrial calcium uniporter
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
6263 RYR3; ryanodine receptor 3
3708 ITPR1; inositol 1,4,5-trisphosphate receptor type 1
3709 ITPR2; inositol 1,4,5-trisphosphate receptor type 2
3710 ITPR3; inositol 1,4,5-trisphosphate receptor type 3
487 ATP2A1; ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
489 ATP2A3; ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
488 ATP2A2; ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
22926 ATF6; activating transcription factor 6
7494 XBP1; X-box binding protein 1
1649 DDIT3; DNA damage inducible transcript 3
2081 ERN1; endoplasmic reticulum to nucleus signaling 1
9451 EIF2AK3; eukaryotic translation initiation factor 2 alpha kinase 3
7186 TRAF2; TNF receptor associated factor 2
4217 MAP3K5; mitogen-activated protein kinase kinase kinase 5
5609 MAP2K7; mitogen-activated protein kinase kinase 7
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
1965 EIF2S1; eukaryotic translation initiation factor 2 subunit alpha
468 ATF4; activating transcription factor 4
5687 PSMA6; proteasome 20S subunit alpha 6
5683 PSMA2; proteasome 20S subunit alpha 2
5685 PSMA4; proteasome 20S subunit alpha 4
5688 PSMA7; proteasome 20S subunit alpha 7
143471 PSMA8; proteasome 20S subunit alpha 8
5686 PSMA5; proteasome 20S subunit alpha 5
5682 PSMA1; proteasome 20S subunit alpha 1
5684 PSMA3; proteasome 20S subunit alpha 3
5694 PSMB6; proteasome 20S subunit beta 6
5695 PSMB7; proteasome 20S subunit beta 7
5691 PSMB3; proteasome 20S subunit beta 3
5690 PSMB2; proteasome 20S subunit beta 2
5693 PSMB5; proteasome 20S subunit beta 5
5689 PSMB1; proteasome 20S subunit beta 1
5692 PSMB4; proteasome 20S subunit beta 4
5701 PSMC2; proteasome 26S subunit, ATPase 2
5700 PSMC1; proteasome 26S subunit, ATPase 1
5704 PSMC4; proteasome 26S subunit, ATPase 4
5706 PSMC6; proteasome 26S subunit, ATPase 6
5702 PSMC3; proteasome 26S subunit, ATPase 3
5705 PSMC5; proteasome 26S subunit, ATPase 5
5708 PSMD2; proteasome 26S subunit ubiquitin receptor, non-ATPase 2
5707 PSMD1; proteasome 26S subunit, non-ATPase 1
5709 PSMD3; proteasome 26S subunit, non-ATPase 3
5715 PSMD9; proteasome 26S subunit, non-ATPase 9
5718 PSMD12; proteasome 26S subunit, non-ATPase 12
5717 PSMD11; proteasome 26S subunit, non-ATPase 11
9861 PSMD6; proteasome 26S subunit, non-ATPase 6
5713 PSMD7; proteasome 26S subunit, non-ATPase 7
5719 PSMD13; proteasome 26S subunit, non-ATPase 13
5710 PSMD4; proteasome 26S subunit ubiquitin receptor, non-ATPase 4
10213 PSMD14; proteasome 26S subunit, non-ATPase 14
5714 PSMD8; proteasome 26S subunit, non-ATPase 8
11047 ADRM1; ADRM1 26S proteasome ubiquitin receptor
7979 SEM1; SEM1 26S proteasome subunit
100506742 CASP12; caspase 12 (gene/pseudogene)
4842 NOS1; nitric oxide synthase 1
823 CAPN1; calpain 1
824 CAPN2; calpain 2
8851 CDK5R1; cyclin dependent kinase 5 regulatory subunit 1
29986 SLC39A2; solute carrier family 39 member 2
29985 SLC39A3; solute carrier family 39 member 3
27173 SLC39A1; solute carrier family 39 member 1
55630 SLC39A4; solute carrier family 39 member 4
283375 SLC39A5; solute carrier family 39 member 5
25800 SLC39A6; solute carrier family 39 member 6
7922 SLC39A7; solute carrier family 39 member 7
64116 SLC39A8; solute carrier family 39 member 8
55334 SLC39A9; solute carrier family 39 member 9
57181 SLC39A10; solute carrier family 39 member 10
201266 SLC39A11; solute carrier family 39 member 11
221074 SLC39A12; solute carrier family 39 member 12
91252 SLC39A13; solute carrier family 39 member 13
23516 SLC39A14; solute carrier family 39 member 14
4891 SLC11A2; solute carrier family 11 member 2
1020 CDK5; cyclin dependent kinase 5
2932 GSK3B; glycogen synthase kinase 3 beta
840 CASP7; caspase 7
22943 DKK1; dickkopf WNT signaling pathway inhibitor 1
27123 DKK2; dickkopf WNT signaling pathway inhibitor 2
27121 DKK4; dickkopf WNT signaling pathway inhibitor 4
7471 WNT1; Wnt family member 1
7472 WNT2; Wnt family member 2
7482 WNT2B; Wnt family member 2B
7473 WNT3; Wnt family member 3
89780 WNT3A; Wnt family member 3A
54361 WNT4; Wnt family member 4
7474 WNT5A; Wnt family member 5A
81029 WNT5B; Wnt family member 5B
7475 WNT6; Wnt family member 6
7476 WNT7A; Wnt family member 7A
7477 WNT7B; Wnt family member 7B
7478 WNT8A; Wnt family member 8A
7479 WNT8B; Wnt family member 8B
7483 WNT9A; Wnt family member 9A
7484 WNT9B; Wnt family member 9B
7480 WNT10B; Wnt family member 10B
80326 WNT10A; Wnt family member 10A
7481 WNT11; Wnt family member 11
51384 WNT16; Wnt family member 16
8321 FZD1; frizzled class receptor 1
8324 FZD7; frizzled class receptor 7
2535 FZD2; frizzled class receptor 2
7976 FZD3; frizzled class receptor 3
8322 FZD4; frizzled class receptor 4
7855 FZD5; frizzled class receptor 5
8325 FZD8; frizzled class receptor 8
8323 FZD6; frizzled class receptor 6
11211 FZD10; frizzled class receptor 10
8326 FZD9; frizzled class receptor 9
4041 LRP5; LDL receptor related protein 5
4040 LRP6; LDL receptor related protein 6
1454 CSNK1E; casein kinase 1 epsilon
102800317 TPTEP2-CSNK1E; TPTEP2-CSNK1E readthrough
1857 DVL3; dishevelled segment polarity protein 3
1856 DVL2; dishevelled segment polarity protein 2
1855 DVL1; dishevelled segment polarity protein 1
10023 FRAT1; FRAT regulator of WNT signaling pathway 1
23401 FRAT2; FRAT regulator of WNT signaling pathway 2
1457 CSNK2A1; casein kinase 2 alpha 1
1459 CSNK2A2; casein kinase 2 alpha 2
283106 CSNK2A3; casein kinase 2 alpha 3
1460 CSNK2B; casein kinase 2 beta
8312 AXIN1; axin 1
8313 AXIN2; axin 2
324 APC; APC regulator of WNT signaling pathway
10297 APC2; APC regulator of WNT signaling pathway 2
1499 CTNNB1; catenin beta 1
122011 CSNK1A1L; casein kinase 1 alpha 1 like
1452 CSNK1A1; casein kinase 1 alpha 1
3798 KIF5A; kinesin family member 5A
3799 KIF5B; kinesin family member 5B
3800 KIF5C; kinesin family member 5C
147700 KLC3; kinesin light chain 3
3831 KLC1; kinesin light chain 1
64837 KLC2; kinesin light chain 2
89953 KLC4; kinesin light chain 4
10376 TUBA1B; tubulin alpha 1b
7277 TUBA4A; tubulin alpha 4a
7278 TUBA3C; tubulin alpha 3c
7846 TUBA1A; tubulin alpha 1a
84790 TUBA1C; tubulin alpha 1c
51807 TUBA8; tubulin alpha 8
112714 TUBA3E; tubulin alpha 3e
113457 TUBA3D; tubulin alpha 3d
79861 TUBAL3; tubulin alpha like 3
84617 TUBB6; tubulin beta 6 class V
203068 TUBB; tubulin beta class I
81027 TUBB1; tubulin beta 1 class VI
7280 TUBB2A; tubulin beta 2A class IIa
10381 TUBB3; tubulin beta 3 class III
10382 TUBB4A; tubulin beta 4A class IVa
347688 TUBB8; tubulin beta 8 class VIII
347733 TUBB2B; tubulin beta 2B class IIb
10383 TUBB4B; tubulin beta 4B class IVb
177 AGER; advanced glycosylation end-product specific receptor
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
27035 NOX1; NADPH oxidase 1
1536 CYBB; cytochrome b-245 beta chain
50507 NOX4; NADPH oxidase 4
5970 RELA; RELA proto-oncogene, NF-kB subunit
4790 NFKB1; nuclear factor kappa B subunit 1
4843 NOS2; nitric oxide synthase 2
5743 PTGS2; prostaglandin-endoperoxide synthase 2
7124 TNF; tumor necrosis factor
3569 IL6; interleukin 6
3552 IL1A; interleukin 1 alpha
3553 IL1B; interleukin 1 beta
1435 CSF1; colony stimulating factor 1
6622 SNCA; synuclein alpha
5610 EIF2AK2; eukaryotic translation initiation factor 2 alpha kinase 2
1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
3630 INS; insulin
3643 INSR; insulin receptor
3667 IRS1; insulin receptor substrate 1
8660 IRS2; insulin receptor substrate 2
8471 IRS4; insulin receptor substrate 4
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
2475 MTOR; mechanistic target of rapamycin kinase
8408 ULK1; unc-51 like autophagy activating kinase 1
9706 ULK2; unc-51 like autophagy activating kinase 2
60673 ATG101; autophagy related 101
9776 ATG13; autophagy related 13
9821 RB1CC1; RB1 inducible coiled-coil 1
55626 AMBRA1; autophagy and beclin 1 regulator 1
8678 BECN1; beclin 1
441925 BECN2; beclin 2
30849 PIK3R4; phosphoinositide-3-kinase regulatory subunit 4
22863 ATG14; autophagy related 14
29982 NRBF2; nuclear receptor binding factor 2
5289 PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3
23130 ATG2A; autophagy related 2A
55102 ATG2B; autophagy related 2B
26100 WIPI2; WD repeat domain, phosphoinositide interacting 2
55062 WIPI1; WD repeat domain, phosphoinositide interacting 1
|
K06704 ADAM10; disintegrin and metalloproteinase domain-containing protein 10 [EC:3.4.24.81]
K06059 ADAM17; disintegrin and metalloproteinase domain-containing protein 17 [EC:3.4.24.86]
K04520 APP; amyloid beta A4 protein
K04532 NAE1; NEDD8-activating enzyme E1 regulatory subunit
K04529 APBB1; amyloid beta A4 precursor protein-binding family B member 1
K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
K04521 BACE1; beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:3.4.23.46]
K07747 BACE2; beta-site APP-cleaving enzyme 2 (memapsin 1) [EC:3.4.23.45]
K20723 RTN3; reticulon-3
K20720 RTN4; reticulon-4
K06170 PSENEN; presenilin enhancer 2
K04505 PSEN1; presenilin 1 [EC:3.4.23.-]
K04522 PSEN2; presenilin 2 [EC:3.4.23.-]
K06171 NCSTN; nicastrin
K06172 APH1; gamma-secretase subunit APH-1
K06172 APH1; gamma-secretase subunit APH-1
K01408 IDE; insulysin [EC:3.4.24.56]
K01389 MME; neprilysin [EC:3.4.24.11]
K04380 MAPT; microtubule-associated protein tau
K03878 ND1; NADH-ubiquinone oxidoreductase chain 1 [EC:7.1.1.2]
K03879 ND2; NADH-ubiquinone oxidoreductase chain 2 [EC:7.1.1.2]
K03880 ND3; NADH-ubiquinone oxidoreductase chain 3 [EC:7.1.1.2]
K03881 ND4; NADH-ubiquinone oxidoreductase chain 4 [EC:7.1.1.2]
K03882 ND4L; NADH-ubiquinone oxidoreductase chain 4L [EC:7.1.1.2]
K03883 ND5; NADH-ubiquinone oxidoreductase chain 5 [EC:7.1.1.2]
K03884 ND6; NADH-ubiquinone oxidoreductase chain 6 [EC:7.1.1.2]
K03942 NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
K03943 NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:7.1.1.2]
K03944 NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
K03945 NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1
K03946 NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2
K03947 NDUFA3; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3
K03948 NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K03948 NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K03949 NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5
K03950 NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6
K03951 NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7
K03952 NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8
K03953 NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9
K03954 NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10
K03955 NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1, acyl-carrier protein
K03956 NDUFA11; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11
K11352 NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12
K11353 NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13
K03957 NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
K03959 NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3
K03960 NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4
K03961 NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5
K03962 NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6
K03963 NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7
K03964 NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8
K03965 NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9
K03966 NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10
K11351 NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
K03934 NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:7.1.1.2]
K03935 NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:7.1.1.2]
K03936 NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:7.1.1.2]
K03937 NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
K03938 NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5
K03939 NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6
K03940 NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:7.1.1.2]
K03941 NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:7.1.1.2]
K03967 NDUFC1; NADH dehydrogenase (ubiquinone) 1 subunit C1
K03968 NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
K03968 NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
K00234 SDHA; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
K00235 SDHB; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
K00236 SDHC; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
K00237 SDHD; succinate dehydrogenase (ubiquinone) membrane anchor subunit
K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
K00413 CYC1; ubiquinol-cytochrome c reductase cytochrome c1 subunit
K00414 QCR1; ubiquinol-cytochrome c reductase core subunit 1
K00415 QCR2; ubiquinol-cytochrome c reductase core subunit 2
K00416 QCR6; ubiquinol-cytochrome c reductase subunit 6
K00416 QCR6; ubiquinol-cytochrome c reductase subunit 6
K00417 QCR7; ubiquinol-cytochrome c reductase subunit 7
K00418 QCR8; ubiquinol-cytochrome c reductase subunit 8
K00419 QCR9; ubiquinol-cytochrome c reductase subunit 9
K00420 QCR10; ubiquinol-cytochrome c reductase subunit 10
K02262 COX3; cytochrome c oxidase subunit 3
K02256 COX1; cytochrome c oxidase subunit 1 [EC:7.1.1.9]
K02261 COX2; cytochrome c oxidase subunit 2
K02263 COX4; cytochrome c oxidase subunit 4
K02263 COX4; cytochrome c oxidase subunit 4
K02264 COX5A; cytochrome c oxidase subunit 5a
K02265 COX5B; cytochrome c oxidase subunit 5b
K02266 COX6A; cytochrome c oxidase subunit 6a
K02266 COX6A; cytochrome c oxidase subunit 6a
K02267 COX6B; cytochrome c oxidase subunit 6b
K02267 COX6B; cytochrome c oxidase subunit 6b
K02268 COX6C; cytochrome c oxidase subunit 6c
K02270 COX7A; cytochrome c oxidase subunit 7a
K02270 COX7A; cytochrome c oxidase subunit 7a
K02270 COX7A; cytochrome c oxidase subunit 7a
K02271 COX7B; cytochrome c oxidase subunit 7b
K02271 COX7B; cytochrome c oxidase subunit 7b
K02272 COX7C; cytochrome c oxidase subunit 7c
K02273 COX8; cytochrome c oxidase subunit 8
K02273 COX8; cytochrome c oxidase subunit 8
K02132 ATPeF1A; F-type H+-transporting ATPase subunit alpha
K02133 ATPeF1B; F-type H+-transporting ATPase subunit beta [EC:7.1.2.2]
K02136 ATPeF1G; F-type H+-transporting ATPase subunit gamma
K02134 ATPeF1D; F-type H+-transporting ATPase subunit delta
K02135 ATPeF1E; F-type H+-transporting ATPase subunit epsilon
K02126 ATPeF0A; F-type H+-transporting ATPase subunit a
K02127 ATPeF0B; F-type H+-transporting ATPase subunit b
K02128 ATPeF0C; F-type H+-transporting ATPase subunit c
K02128 ATPeF0C; F-type H+-transporting ATPase subunit c
K02128 ATPeF0C; F-type H+-transporting ATPase subunit c
K02138 ATPeF0D; F-type H+-transporting ATPase subunit d
K02137 ATPeF0O; F-type H+-transporting ATPase subunit O
K02131 ATPeF0F6; F-type H+-transporting ATPase subunit 6
K02125 ATPeF08; F-type H+-transporting ATPase subunit 8
K08683 HSD17B10; 3-hydroxyacyl-CoA dehydrogenase / 3-hydroxy-2-methylbutyryl-CoA dehydrogenase [EC:1.1.1.35 1.1.1.178]
K05864 PPID; peptidyl-prolyl isomerase D [EC:5.2.1.8]
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
K01059 LPL; lipoprotein lipase [EC:3.1.1.34]
K04524 APOE; apolipoprotein E
K04550 LRP1; low-density lipoprotein receptor-related protein 1 (alpha-2-macroglobulin receptor)
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K03158 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K02158 BAD; Bcl-2-antagonist of cell death
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04129 CHRM1; muscarinic acetylcholine receptor M1
K04131 CHRM3; muscarinic acetylcholine receptor M3
K04133 CHRM5; muscarinic acetylcholine receptor M5
K04604 GRM5; metabotropic glutamate receptor 5
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K05211 GRIN2C; glutamate receptor ionotropic, NMDA 2C
K05212 GRIN2D; glutamate receptor ionotropic, NMDA 2D
K04850 CACNA1C; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S; voltage-dependent calcium channel L type alpha-1S
K04809 CHRNA7; nicotinic acetylcholine receptor alpha-7
K20858 MCU; calcium uniporter protein, mitochondrial
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04963 RYR3; ryanodine receptor 3
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K05853 ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
K05853 ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
K05853 ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
K09054 ATF6A; cyclic AMP-dependent transcription factor ATF-6 alpha
K09027 XBP1; X box-binding protein 1
K04452 DDIT3; DNA damage-inducible transcript 3
K08852 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
K08860 EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K03237 EIF2S1; translation initiation factor 2 subunit 1
K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
K02730 PSMA6; 20S proteasome subunit alpha 1 [EC:3.4.25.1]
K02726 PSMA2; 20S proteasome subunit alpha 2 [EC:3.4.25.1]
K02728 PSMA4; 20S proteasome subunit alpha 3 [EC:3.4.25.1]
K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
K02729 PSMA5; 20S proteasome subunit alpha 5 [EC:3.4.25.1]
K02725 PSMA1; 20S proteasome subunit alpha 6 [EC:3.4.25.1]
K02727 PSMA3; 20S proteasome subunit alpha 7 [EC:3.4.25.1]
K02738 PSMB6; 20S proteasome subunit beta 1 [EC:3.4.25.1]
K02739 PSMB7; 20S proteasome subunit beta 2 [EC:3.4.25.1]
K02735 PSMB3; 20S proteasome subunit beta 3 [EC:3.4.25.1]
K02734 PSMB2; 20S proteasome subunit beta 4 [EC:3.4.25.1]
K02737 PSMB5; 20S proteasome subunit beta 5 [EC:3.4.25.1]
K02732 PSMB1; 20S proteasome subunit beta 6 [EC:3.4.25.1]
K02736 PSMB4; 20S proteasome subunit beta 7 [EC:3.4.25.1]
K03061 PSMC2; 26S proteasome regulatory subunit T1
K03062 PSMC1; 26S proteasome regulatory subunit T2
K03063 PSMC4; 26S proteasome regulatory subunit T3
K03064 PSMC6; 26S proteasome regulatory subunit T4
K03065 PSMC3; 26S proteasome regulatory subunit T5
K03066 PSMC5; 26S proteasome regulatory subunit T6
K03028 PSMD2; 26S proteasome regulatory subunit N1
K03032 PSMD1; 26S proteasome regulatory subunit N2
K03033 PSMD3; 26S proteasome regulatory subunit N3
K06693 PSMD9; 26S proteasome regulatory subunit N4
K03035 PSMD12; 26S proteasome regulatory subunit N5
K03036 PSMD11; 26S proteasome regulatory subunit N6
K03037 PSMD6; 26S proteasome regulatory subunit N7
K03038 PSMD7; 26S proteasome regulatory subunit N8
K03039 PSMD13; 26S proteasome regulatory subunit N9
K03029 PSMD4; 26S proteasome regulatory subunit N10
K03030 PSMD14; 26S proteasome regulatory subunit N11
K03031 PSMD8; 26S proteasome regulatory subunit N12
K06691 RPN13; 26S proteasome regulatory subunit N13
K10881 SHFM1; 26 proteasome complex subunit DSS1
K04741 CASP12; caspase 12 [EC:3.4.22.-]
K13240 NOS1; nitric-oxide synthase, brain [EC:1.14.13.39]
K01367 CAPN1; calpain-1 [EC:3.4.22.52]
K03853 CAPN2; calpain-2 [EC:3.4.22.53]
K11716 CDK5R1; cyclin-dependent kinase 5 activator 1
K14709 SLC39A1_2_3; solute carrier family 39 (zinc transporter), member 1/2/3
K14709 SLC39A1_2_3; solute carrier family 39 (zinc transporter), member 1/2/3
K14709 SLC39A1_2_3; solute carrier family 39 (zinc transporter), member 1/2/3
K14710 SLC39A4; solute carrier family 39 (zinc transporter), member 4
K14711 SLC39A5; solute carrier family 39 (zinc transporter), member 5
K14712 SLC39A6; solute carrier family 39 (zinc transporter), member 6
K14713 SLC39A7; solute carrier family 39 (zinc transporter), member 7
K14714 SLC39A8; solute carrier family 39 (zinc transporter), member 8
K14715 SLC39A9; solute carrier family 39 (zinc transporter), member 9
K14716 SLC39A10; solute carrier family 39 (zinc transporter), member 10
K14717 SLC39A11; solute carrier family 39 (zinc transporter), member 11
K14718 SLC39A12; solute carrier family 39 (zinc transporter), member 12
K14719 SLC39A13; solute carrier family 39 (zinc transporter), member 13
K14720 SLC39A14; solute carrier family 39 (zinc transporter), member 14
K21398 SLC11A2; natural resistance-associated macrophage protein 2
K02090 CDK5; cyclin-dependent kinase 5 [EC:2.7.11.22]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K02165 DKK1_2_4; dickkopf 1/2/4
K02165 DKK1_2_4; dickkopf 1/2/4
K02165 DKK1_2_4; dickkopf 1/2/4
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03115 CSNK2B; casein kinase II subunit beta
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K02105 CTNNB1; catenin beta 1
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K10396 KIF5; kinesin family member 5
K10396 KIF5; kinesin family member 5
K10396 KIF5; kinesin family member 5
K10407 KLC; kinesin light chain
K10407 KLC; kinesin light chain
K10407 KLC; kinesin light chain
K10407 KLC; kinesin light chain
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07375 TUBB; tubulin beta
K07375 TUBB; tubulin beta
K07375 TUBB; tubulin beta
K07375 TUBB; tubulin beta
K07375 TUBB; tubulin beta
K07375 TUBB; tubulin beta
K07375 TUBB; tubulin beta
K07375 TUBB; tubulin beta
K07375 TUBB; tubulin beta
K19722 AGER; receptor for advanced glycosylation end products
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K08008 NOX1; NADPH oxidase 1
K21421 NOX2; NADPH oxidase 2 [EC:1.-.-.-]
K21423 NOX4; NADPH oxidase 4 [EC:1.6.3.-]
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K03156 TNF; tumor necrosis factor superfamily, member 2
K05405 IL6; interleukin 6
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K05453 CSF1; macrophage colony-stimulating factor 1
K04528 SNCA; alpha-synuclein
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04526 INS; insulin
K04527 INSR; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K17446 IRS4; insulin receptor substrate 4
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K21357 ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
K08269 ULK2; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
K19730 ATG101; autophagy-related protein 101
K08331 ATG13; autophagy-related protein 13
K17589 RB1CC1; RB1-inducible coiled-coil protein 1
K17985 AMBRA1; activating molecule in BECN1-regulated autophagy protein 1
K08334 BECN; beclin
K08334 BECN; beclin
K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
K17889 ATG14L; beclin 1-associated autophagy-related key regulator
K21246 NRBF2; nuclear receptor-binding factor 2
K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
K17906 ATG2; autophagy-related protein 2
K17906 ATG2; autophagy-related protein 2
K17908 WIPI1_2; autophagy-related protein 18
K17908 WIPI1_2; autophagy-related protein 18
|
05012 Parkinson disease [PATH:hsa05012]
|
05014 Amyotrophic lateral sclerosis [PATH:hsa05014]
|
05016 Huntington disease [PATH:hsa05016]
|
05017 Spinocerebellar ataxia [PATH:hsa05017]
|
05020 Prion disease [PATH:hsa05020]
|
05022 Pathways of neurodegeneration - multiple diseases [PATH:hsa05022]
|
351 APP; amyloid beta precursor protein
4137 MAPT; microtubule associated protein tau
6622 SNCA; synuclein alpha
23435 TARDBP; TAR DNA binding protein
2521 FUS; FUS RNA binding protein
6647 SOD1; superoxide dismutase 1
11273 ATXN2L; ataxin 2 like
6311 ATXN2; ataxin 2
3064 HTT; huntingtin
342371 ATXN1L; ataxin 1 like
6310 ATXN1; ataxin 1
4287 ATXN3; ataxin 3
92552 ATXN3L; ataxin 3 like
5621 PRNP; prion protein (Kanno blood group)
1128 CHRM1; cholinergic receptor muscarinic 1
1131 CHRM3; cholinergic receptor muscarinic 3
1133 CHRM5; cholinergic receptor muscarinic 5
6712 SPTBN2; spectrin beta, non-erythrocytic 2
2911 GRM1; glutamate metabotropic receptor 1
2915 GRM5; glutamate metabotropic receptor 5
2776 GNAQ; G protein subunit alpha q
5071 PRKN; parkin RBR E3 ubiquitin protein ligase
23236 PLCB1; phospholipase C beta 1
5330 PLCB2; phospholipase C beta 2
5331 PLCB3; phospholipase C beta 3
5332 PLCB4; phospholipase C beta 4
5335 PLCG1; phospholipase C gamma 1
5578 PRKCA; protein kinase C alpha
5579 PRKCB; protein kinase C beta
5582 PRKCG; protein kinase C gamma
7222 TRPC3; transient receptor potential cation channel subfamily C member 3
10280 SIGMAR1; sigma non-opioid intracellular receptor 1
3708 ITPR1; inositol 1,4,5-trisphosphate receptor type 1
3709 ITPR2; inositol 1,4,5-trisphosphate receptor type 2
3710 ITPR3; inositol 1,4,5-trisphosphate receptor type 3
6261 RYR1; ryanodine receptor 1
6262 RYR2; ryanodine receptor 2
6263 RYR3; ryanodine receptor 3
5173 PDYN; prodynorphin
1742 DLG4; discs large MAGUK scaffold protein 4
2902 GRIN1; glutamate ionotropic receptor NMDA type subunit 1
2903 GRIN2A; glutamate ionotropic receptor NMDA type subunit 2A
2904 GRIN2B; glutamate ionotropic receptor NMDA type subunit 2B
2905 GRIN2C; glutamate ionotropic receptor NMDA type subunit 2C
2906 GRIN2D; glutamate ionotropic receptor NMDA type subunit 2D
2890 GRIA1; glutamate ionotropic receptor AMPA type subunit 1
2891 GRIA2; glutamate ionotropic receptor AMPA type subunit 2
2892 GRIA3; glutamate ionotropic receptor AMPA type subunit 3
2893 GRIA4; glutamate ionotropic receptor AMPA type subunit 4
774 CACNA1B; calcium voltage-gated channel subunit alpha1 B
775 CACNA1C; calcium voltage-gated channel subunit alpha1 C
776 CACNA1D; calcium voltage-gated channel subunit alpha1 D
778 CACNA1F; calcium voltage-gated channel subunit alpha1 F
779 CACNA1S; calcium voltage-gated channel subunit alpha1 S
6804 STX1A; syntaxin 1A
1139 CHRNA7; cholinergic receptor nicotinic alpha 7 subunit
487 ATP2A1; ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
489 ATP2A3; ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
488 ATP2A2; ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
5663 PSEN1; presenilin 1
5664 PSEN2; presenilin 2
79139 DERL1; derlin 1
7415 VCP; valosin containing protein
7311 UBA52; ubiquitin A-52 residue ribosomal protein fusion product 1
6233 RPS27A; ribosomal protein S27a
7314 UBB; ubiquitin B
7316 UBC; ubiquitin C
5687 PSMA6; proteasome 20S subunit alpha 6
5683 PSMA2; proteasome 20S subunit alpha 2
5685 PSMA4; proteasome 20S subunit alpha 4
5688 PSMA7; proteasome 20S subunit alpha 7
143471 PSMA8; proteasome 20S subunit alpha 8
5686 PSMA5; proteasome 20S subunit alpha 5
5682 PSMA1; proteasome 20S subunit alpha 1
5684 PSMA3; proteasome 20S subunit alpha 3
5694 PSMB6; proteasome 20S subunit beta 6
5695 PSMB7; proteasome 20S subunit beta 7
5691 PSMB3; proteasome 20S subunit beta 3
5690 PSMB2; proteasome 20S subunit beta 2
5693 PSMB5; proteasome 20S subunit beta 5
5689 PSMB1; proteasome 20S subunit beta 1
5692 PSMB4; proteasome 20S subunit beta 4
5701 PSMC2; proteasome 26S subunit, ATPase 2
5700 PSMC1; proteasome 26S subunit, ATPase 1
5704 PSMC4; proteasome 26S subunit, ATPase 4
5706 PSMC6; proteasome 26S subunit, ATPase 6
5702 PSMC3; proteasome 26S subunit, ATPase 3
5705 PSMC5; proteasome 26S subunit, ATPase 5
5708 PSMD2; proteasome 26S subunit ubiquitin receptor, non-ATPase 2
5707 PSMD1; proteasome 26S subunit, non-ATPase 1
5709 PSMD3; proteasome 26S subunit, non-ATPase 3
5715 PSMD9; proteasome 26S subunit, non-ATPase 9
5718 PSMD12; proteasome 26S subunit, non-ATPase 12
5717 PSMD11; proteasome 26S subunit, non-ATPase 11
9861 PSMD6; proteasome 26S subunit, non-ATPase 6
5713 PSMD7; proteasome 26S subunit, non-ATPase 7
5719 PSMD13; proteasome 26S subunit, non-ATPase 13
5710 PSMD4; proteasome 26S subunit ubiquitin receptor, non-ATPase 4
10213 PSMD14; proteasome 26S subunit, non-ATPase 14
5714 PSMD8; proteasome 26S subunit, non-ATPase 8
11047 ADRM1; ADRM1 26S proteasome ubiquitin receptor
7979 SEM1; SEM1 26S proteasome subunit
7345 UCHL1; ubiquitin C-terminal hydrolase L1
7317 UBA1; ubiquitin like modifier activating enzyme 1
7318 UBA7; ubiquitin like modifier activating enzyme 7
7332 UBE2L3; ubiquitin conjugating enzyme E2 L3
9246 UBE2L6; ubiquitin conjugating enzyme E2 L6
118424 UBE2J2; ubiquitin conjugating enzyme E2 J2
51465 UBE2J1; ubiquitin conjugating enzyme E2 J1
7327 UBE2G2; ubiquitin conjugating enzyme E2 G2
7326 UBE2G1; ubiquitin conjugating enzyme E2 G1
2861 GPR37; G protein-coupled receptor 37
5413 SEPTIN5; septin 5
9627 SNCAIP; synuclein alpha interacting protein
3309 HSPA5; heat shock protein family A (Hsp70) member 5
9217 VAPB; VAMP associated protein B and C
22926 ATF6; activating transcription factor 6
1649 DDIT3; DNA damage inducible transcript 3
7494 XBP1; X-box binding protein 1
2081 ERN1; endoplasmic reticulum to nucleus signaling 1
7186 TRAF2; TNF receptor associated factor 2
4217 MAP3K5; mitogen-activated protein kinase kinase kinase 5
5609 MAP2K7; mitogen-activated protein kinase kinase 7
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
100506742 CASP12; caspase 12 (gene/pseudogene)
4294 MAP3K10; mitogen-activated protein kinase kinase kinase 10
9451 EIF2AK3; eukaryotic translation initiation factor 2 alpha kinase 3
1965 EIF2S1; eukaryotic translation initiation factor 2 subunit alpha
468 ATF4; activating transcription factor 4
6531 SLC6A3; solute carrier family 6 member 3
65018 PINK1; PTEN induced kinase 1
4535 ND1; NADH dehydrogenase subunit 1
4536 ND2; NADH dehydrogenase subunit 2
4537 ND3; NADH dehydrogenase subunit 3
4538 ND4; NADH dehydrogenase subunit 4
4539 ND4L; NADH dehydrogenase subunit 4L
4540 ND5; NADH dehydrogenase subunit 5
4541 ND6; NADH dehydrogenase subunit 6
4723 NDUFV1; NADH:ubiquinone oxidoreductase core subunit V1
4729 NDUFV2; NADH:ubiquinone oxidoreductase core subunit V2
4731 NDUFV3; NADH:ubiquinone oxidoreductase subunit V3
4694 NDUFA1; NADH:ubiquinone oxidoreductase subunit A1
4695 NDUFA2; NADH:ubiquinone oxidoreductase subunit A2
4696 NDUFA3; NADH:ubiquinone oxidoreductase subunit A3
4697 NDUFA4; NDUFA4 mitochondrial complex associated
56901 NDUFA4L2; NDUFA4 mitochondrial complex associated like 2
4698 NDUFA5; NADH:ubiquinone oxidoreductase subunit A5
4700 NDUFA6; NADH:ubiquinone oxidoreductase subunit A6
4701 NDUFA7; NADH:ubiquinone oxidoreductase subunit A7
4702 NDUFA8; NADH:ubiquinone oxidoreductase subunit A8
4704 NDUFA9; NADH:ubiquinone oxidoreductase subunit A9
4705 NDUFA10; NADH:ubiquinone oxidoreductase subunit A10
4706 NDUFAB1; NADH:ubiquinone oxidoreductase subunit AB1
126328 NDUFA11; NADH:ubiquinone oxidoreductase subunit A11
55967 NDUFA12; NADH:ubiquinone oxidoreductase subunit A12
51079 NDUFA13; NADH:ubiquinone oxidoreductase subunit A13
4707 NDUFB1; NADH:ubiquinone oxidoreductase subunit B1
4708 NDUFB2; NADH:ubiquinone oxidoreductase subunit B2
4709 NDUFB3; NADH:ubiquinone oxidoreductase subunit B3
4710 NDUFB4; NADH:ubiquinone oxidoreductase subunit B4
4711 NDUFB5; NADH:ubiquinone oxidoreductase subunit B5
4712 NDUFB6; NADH:ubiquinone oxidoreductase subunit B6
4713 NDUFB7; NADH:ubiquinone oxidoreductase subunit B7
4714 NDUFB8; NADH:ubiquinone oxidoreductase subunit B8
4715 NDUFB9; NADH:ubiquinone oxidoreductase subunit B9
4716 NDUFB10; NADH:ubiquinone oxidoreductase subunit B10
54539 NDUFB11; NADH:ubiquinone oxidoreductase subunit B11
4719 NDUFS1; NADH:ubiquinone oxidoreductase core subunit S1
4720 NDUFS2; NADH:ubiquinone oxidoreductase core subunit S2
4722 NDUFS3; NADH:ubiquinone oxidoreductase core subunit S3
4724 NDUFS4; NADH:ubiquinone oxidoreductase subunit S4
4725 NDUFS5; NADH:ubiquinone oxidoreductase subunit S5
4726 NDUFS6; NADH:ubiquinone oxidoreductase subunit S6
374291 NDUFS7; NADH:ubiquinone oxidoreductase core subunit S7
4728 NDUFS8; NADH:ubiquinone oxidoreductase core subunit S8
4717 NDUFC1; NADH:ubiquinone oxidoreductase subunit C1
4718 NDUFC2; NADH:ubiquinone oxidoreductase subunit C2
100532726 NDUFC2-KCTD14; NDUFC2-KCTD14 readthrough
6389 SDHA; succinate dehydrogenase complex flavoprotein subunit A
6390 SDHB; succinate dehydrogenase complex iron sulfur subunit B
6391 SDHC; succinate dehydrogenase complex subunit C
6392 SDHD; succinate dehydrogenase complex subunit D
7386 UQCRFS1; ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
4519 CYTB; cytochrome b
1537 CYC1; cytochrome c1
7384 UQCRC1; ubiquinol-cytochrome c reductase core protein 1
7385 UQCRC2; ubiquinol-cytochrome c reductase core protein 2
7388 UQCRH; ubiquinol-cytochrome c reductase hinge protein
440567 UQCRHL; ubiquinol-cytochrome c reductase hinge protein like
7381 UQCRB; ubiquinol-cytochrome c reductase binding protein
27089 UQCRQ; ubiquinol-cytochrome c reductase complex III subunit VII
29796 UQCR10; ubiquinol-cytochrome c reductase, complex III subunit X
10975 UQCR11; ubiquinol-cytochrome c reductase, complex III subunit XI
4514 COX3; cytochrome c oxidase subunit III
4512 COX1; cytochrome c oxidase subunit I
4513 COX2; cytochrome c oxidase subunit II
84701 COX4I2; cytochrome c oxidase subunit 4I2
1327 COX4I1; cytochrome c oxidase subunit 4I1
9377 COX5A; cytochrome c oxidase subunit 5A
1329 COX5B; cytochrome c oxidase subunit 5B
1337 COX6A1; cytochrome c oxidase subunit 6A1
1339 COX6A2; cytochrome c oxidase subunit 6A2
1340 COX6B1; cytochrome c oxidase subunit 6B1
125965 COX6B2; cytochrome c oxidase subunit 6B2
1345 COX6C; cytochrome c oxidase subunit 6C
1346 COX7A1; cytochrome c oxidase subunit 7A1
1347 COX7A2; cytochrome c oxidase subunit 7A2
9167 COX7A2L; cytochrome c oxidase subunit 7A2 like
1349 COX7B; cytochrome c oxidase subunit 7B
170712 COX7B2; cytochrome c oxidase subunit 7B2
1350 COX7C; cytochrome c oxidase subunit 7C
341947 COX8C; cytochrome c oxidase subunit 8C
1351 COX8A; cytochrome c oxidase subunit 8A
498 ATP5F1A; ATP synthase F1 subunit alpha
506 ATP5F1B; ATP synthase F1 subunit beta
509 ATP5F1C; ATP synthase F1 subunit gamma
513 ATP5F1D; ATP synthase F1 subunit delta
514 ATP5F1E; ATP synthase F1 subunit epsilon
4508 ATP6; ATP synthase F0 subunit 6
515 ATP5PB; ATP synthase peripheral stalk-membrane subunit b
516 ATP5MC1; ATP synthase membrane subunit c locus 1
517 ATP5MC2; ATP synthase membrane subunit c locus 2
518 ATP5MC3; ATP synthase membrane subunit c locus 3
10476 ATP5PD; ATP synthase peripheral stalk subunit d
539 ATP5PO; ATP synthase peripheral stalk subunit OSCP
522 ATP5PF; ATP synthase peripheral stalk subunit F6
4509 ATP8; ATP synthase F0 subunit 8
596 BCL2; BCL2 apoptosis regulator
7416 VDAC1; voltage dependent anion channel 1
10452 TOMM40; translocase of outer mitochondrial membrane 40
84134 TOMM40L; translocase of outer mitochondrial membrane 40 like
90550 MCU; mitochondrial calcium uniporter
810 CALML3; calmodulin like 3
805 CALM2; calmodulin 2
808 CALM3; calmodulin 3
801 CALM1; calmodulin 1
163688 CALML6; calmodulin like 6
51806 CALML5; calmodulin like 5
91860 CALML4; calmodulin like 4
5530 PPP3CA; protein phosphatase 3 catalytic subunit alpha
5532 PPP3CB; protein phosphatase 3 catalytic subunit beta
5533 PPP3CC; protein phosphatase 3 catalytic subunit gamma
5534 PPP3R1; protein phosphatase 3 regulatory subunit B, alpha
5535 PPP3R2; protein phosphatase 3 regulatory subunit B, beta
572 BAD; BCL2 associated agonist of cell death
356 FASLG; Fas ligand
355 FAS; Fas cell surface death receptor
8772 FADD; Fas associated via death domain
841 CASP8; caspase 8
637 BID; BH3 interacting domain death agonist
581 BAX; BCL2 associated X, apoptosis regulator
578 BAK1; BCL2 antagonist/killer 1
120892 LRRK2; leucine rich repeat kinase 2
27429 HTRA2; HtrA serine peptidase 2
10131 TRAP1; TNF receptor associated protein 1
7417 VDAC2; voltage dependent anion channel 2
7419 VDAC3; voltage dependent anion channel 3
291 SLC25A4; solute carrier family 25 member 4
292 SLC25A5; solute carrier family 25 member 5
293 SLC25A6; solute carrier family 25 member 6
83447 SLC25A31; solute carrier family 25 member 31
10105 PPIF; peptidylprolyl isomerase F
54205 CYCS; cytochrome c, somatic
317 APAF1; apoptotic peptidase activating factor 1
842 CASP9; caspase 9
836 CASP3; caspase 3
3092 HIP1; huntingtin interacting protein 1
55081 IFT57; intraflagellar transport 57
3028 HSD17B10; hydroxysteroid 17-beta dehydrogenase 10
5481 PPID; peptidylprolyl isomerase D
11315 PARK7; Parkinsonism associated deglycase
598 BCL2L1; BCL2 like 1
55669 MFN1; mitofusin 1
9927 MFN2; mitofusin 2
10133 OPTN; optineurin
8878 SQSTM1; sequestosome 1
440738 MAP1LC3C; microtubule associated protein 1 light chain 3 gamma
81631 MAP1LC3B; microtubule associated protein 1 light chain 3 beta
84557 MAP1LC3A; microtubule associated protein 1 light chain 3 alpha
643246 MAP1LC3B2; microtubule associated protein 1 light chain 3 beta 2
29110 TBK1; TANK binding kinase 1
10010 TANK; TRAF family member associated NFKB activator
55255 WDR41; WD repeat domain 41
140775 SMCR8; SMCR8-C9orf72 complex subunit
203228 C9orf72; C9orf72-SMCR8 complex subunit
4218 RAB8A; RAB8A, member RAS oncogene family
116442 RAB39B; RAB39B, member RAS oncogene family
5861 RAB1A; RAB1A, member RAS oncogene family
2475 MTOR; mechanistic target of rapamycin kinase
8408 ULK1; unc-51 like autophagy activating kinase 1
9706 ULK2; unc-51 like autophagy activating kinase 2
60673 ATG101; autophagy related 101
9776 ATG13; autophagy related 13
9821 RB1CC1; RB1 inducible coiled-coil 1
55626 AMBRA1; autophagy and beclin 1 regulator 1
8678 BECN1; beclin 1
441925 BECN2; beclin 2
30849 PIK3R4; phosphoinositide-3-kinase regulatory subunit 4
22863 ATG14; autophagy related 14
29982 NRBF2; nuclear receptor binding factor 2
5289 PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3
23130 ATG2A; autophagy related 2A
55102 ATG2B; autophagy related 2B
26100 WIPI2; WD repeat domain, phosphoinositide interacting 2
55062 WIPI1; WD repeat domain, phosphoinositide interacting 1
53349 ZFYVE1; zinc finger FYVE-type containing 1
57679 ALS2; alsin Rho guanine nucleotide exchange factor ALS2
5868 RAB5A; RAB5A, member RAS oncogene family
5879 RAC1; Rac family small GTPase 1
25978 CHMP2B; charged multivesicular body protein 2B
9896 FIG4; FIG4 phosphoinositide 5-phosphatase
80208 SPG11; SPG11 vesicle trafficking associated, spatacsin
7124 TNF; tumor necrosis factor
7132 TNFRSF1A; TNF receptor superfamily member 1A
7133 TNFRSF1B; TNF receptor superfamily member 1B
1616 DAXX; death domain associated protein
5606 MAP2K3; mitogen-activated protein kinase kinase 3
5608 MAP2K6; mitogen-activated protein kinase kinase 6
5600 MAPK11; mitogen-activated protein kinase 11
6300 MAPK12; mitogen-activated protein kinase 12
5603 MAPK13; mitogen-activated protein kinase 13
1432 MAPK14; mitogen-activated protein kinase 14
4842 NOS1; nitric oxide synthase 1
9973 CCS; copper chaperone for superoxide dismutase
257202 GPX6; glutathione peroxidase 6
2882 GPX7; glutathione peroxidase 7
2877 GPX2; glutathione peroxidase 2
2878 GPX3; glutathione peroxidase 3
2876 GPX1; glutathione peroxidase 1
2880 GPX5; glutathione peroxidase 5
493869 GPX8; glutathione peroxidase 8 (putative)
847 CAT; catalase
5630 PRPH; peripherin
4747 NEFL; neurofilament light chain
4741 NEFM; neurofilament medium chain
4744 NEFH; neurofilament heavy chain
3798 KIF5A; kinesin family member 5A
3799 KIF5B; kinesin family member 5B
3800 KIF5C; kinesin family member 5C
147700 KLC3; kinesin light chain 3
3831 KLC1; kinesin light chain 1
64837 KLC2; kinesin light chain 2
89953 KLC4; kinesin light chain 4
10376 TUBA1B; tubulin alpha 1b
7277 TUBA4A; tubulin alpha 4a
7278 TUBA3C; tubulin alpha 3c
7846 TUBA1A; tubulin alpha 1a
84790 TUBA1C; tubulin alpha 1c
51807 TUBA8; tubulin alpha 8
112714 TUBA3E; tubulin alpha 3e
113457 TUBA3D; tubulin alpha 3d
79861 TUBAL3; tubulin alpha like 3
84617 TUBB6; tubulin beta 6 class V
203068 TUBB; tubulin beta class I
81027 TUBB1; tubulin beta 1 class VI
7280 TUBB2A; tubulin beta 2A class IIa
10381 TUBB3; tubulin beta 3 class III
10382 TUBB4A; tubulin beta 4A class IVa
347688 TUBB8; tubulin beta 8 class VIII
347733 TUBB2B; tubulin beta 2B class IIb
10383 TUBB4B; tubulin beta 4B class IVb
2932 GSK3B; glycogen synthase kinase 3 beta
1457 CSNK2A1; casein kinase 2 alpha 1
1459 CSNK2A2; casein kinase 2 alpha 2
283106 CSNK2A3; casein kinase 2 alpha 3
1460 CSNK2B; casein kinase 2 beta
627 BDNF; brain derived neurotrophic factor
1639 DCTN1; dynactin subunit 1
10540 DCTN2; dynactin subunit 2
11258 DCTN3; dynactin subunit 3
51164 DCTN4; dynactin subunit 4
84516 DCTN5; dynactin subunit 5
10671 DCTN6; dynactin subunit 6
10121 ACTR1A; actin related protein 1A
10120 ACTR1B; actin related protein 1B
55860 ACTR10; actin related protein 10
9001 HAP1; huntingtin associated protein 1
25981 DNAH1; dynein axonemal heavy chain 1
55567 DNAH3; dynein axonemal heavy chain 3
146754 DNAH2; dynein axonemal heavy chain 2
56171 DNAH7; dynein axonemal heavy chain 7
1767 DNAH5; dynein axonemal heavy chain 5
1768 DNAH6; dynein axonemal heavy chain 6
1770 DNAH9; dynein axonemal heavy chain 9
8701 DNAH11; dynein axonemal heavy chain 11
201625 DNAH12; dynein axonemal heavy chain 12
127602 DNAH14; dynein axonemal heavy chain 14
1769 DNAH8; dynein axonemal heavy chain 8
196385 DNAH10; dynein axonemal heavy chain 10
8632 DNAH17; dynein axonemal heavy chain 17
7802 DNALI1; dynein axonemal light intermediate chain 1
27019 DNAI1; dynein axonemal intermediate chain 1
64446 DNAI2; dynein axonemal intermediate chain 2
83544 DNAL1; dynein axonemal light chain 1
10126 DNAL4; dynein axonemal light chain 4
815 CAMK2A; calcium/calmodulin dependent protein kinase II alpha
817 CAMK2D; calcium/calmodulin dependent protein kinase II delta
816 CAMK2B; calcium/calmodulin dependent protein kinase II beta
818 CAMK2G; calcium/calmodulin dependent protein kinase II gamma
823 CAPN1; calpain 1
824 CAPN2; calpain 2
8851 CDK5R1; cyclin dependent kinase 5 regulatory subunit 1
1020 CDK5; cyclin dependent kinase 5
840 CASP7; caspase 7
22943 DKK1; dickkopf WNT signaling pathway inhibitor 1
27123 DKK2; dickkopf WNT signaling pathway inhibitor 2
27121 DKK4; dickkopf WNT signaling pathway inhibitor 4
7471 WNT1; Wnt family member 1
7472 WNT2; Wnt family member 2
7482 WNT2B; Wnt family member 2B
7473 WNT3; Wnt family member 3
89780 WNT3A; Wnt family member 3A
54361 WNT4; Wnt family member 4
7474 WNT5A; Wnt family member 5A
81029 WNT5B; Wnt family member 5B
7475 WNT6; Wnt family member 6
7476 WNT7A; Wnt family member 7A
7477 WNT7B; Wnt family member 7B
7478 WNT8A; Wnt family member 8A
7479 WNT8B; Wnt family member 8B
7483 WNT9A; Wnt family member 9A
7484 WNT9B; Wnt family member 9B
7480 WNT10B; Wnt family member 10B
80326 WNT10A; Wnt family member 10A
7481 WNT11; Wnt family member 11
51384 WNT16; Wnt family member 16
8321 FZD1; frizzled class receptor 1
8324 FZD7; frizzled class receptor 7
2535 FZD2; frizzled class receptor 2
7976 FZD3; frizzled class receptor 3
8322 FZD4; frizzled class receptor 4
7855 FZD5; frizzled class receptor 5
8325 FZD8; frizzled class receptor 8
8323 FZD6; frizzled class receptor 6
11211 FZD10; frizzled class receptor 10
8326 FZD9; frizzled class receptor 9
4041 LRP5; LDL receptor related protein 5
4040 LRP6; LDL receptor related protein 6
1454 CSNK1E; casein kinase 1 epsilon
102800317 TPTEP2-CSNK1E; TPTEP2-CSNK1E readthrough
1857 DVL3; dishevelled segment polarity protein 3
1856 DVL2; dishevelled segment polarity protein 2
1855 DVL1; dishevelled segment polarity protein 1
10023 FRAT1; FRAT regulator of WNT signaling pathway 1
23401 FRAT2; FRAT regulator of WNT signaling pathway 2
8312 AXIN1; axin 1
8313 AXIN2; axin 2
324 APC; APC regulator of WNT signaling pathway
10297 APC2; APC regulator of WNT signaling pathway 2
1499 CTNNB1; catenin beta 1
122011 CSNK1A1L; casein kinase 1 alpha 1 like
1452 CSNK1A1; casein kinase 1 alpha 1
177 AGER; advanced glycosylation end-product specific receptor
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
27035 NOX1; NADPH oxidase 1
1536 CYBB; cytochrome b-245 beta chain
50507 NOX4; NADPH oxidase 4
5970 RELA; RELA proto-oncogene, NF-kB subunit
4790 NFKB1; nuclear factor kappa B subunit 1
4843 NOS2; nitric oxide synthase 2
5743 PTGS2; prostaglandin-endoperoxide synthase 2
3569 IL6; interleukin 6
3552 IL1A; interleukin 1 alpha
3553 IL1B; interleukin 1 beta
1435 CSF1; colony stimulating factor 1
|
K04520 APP; amyloid beta A4 protein
K04380 MAPT; microtubule-associated protein tau
K04528 SNCA; alpha-synuclein
K23600 TARDBP; TAR DNA-binding protein 43
K13098 TLS; RNA-binding protein FUS
K04565 SOD1; superoxide dismutase, Cu-Zn family [EC:1.15.1.1]
K23625 ATXN2_2L; ataxin 2/2L
K23625 ATXN2_2L; ataxin 2/2L
K04533 HD; huntingtin
K23616 ATXN1_1L; ataxin 1/1L
K23616 ATXN1_1L; ataxin 1/1L
K11863 ATXN3; Ataxin-3 [EC:3.4.22.-]
K11863 ATXN3; Ataxin-3 [EC:3.4.22.-]
K05634 PRNP; prion protein
K04129 CHRM1; muscarinic acetylcholine receptor M1
K04131 CHRM3; muscarinic acetylcholine receptor M3
K04133 CHRM5; muscarinic acetylcholine receptor M5
K23932 SPTBN2; spectrin beta, non-erythrocytic 2
K04603 GRM1; metabotropic glutamate receptor 1
K04604 GRM5; metabotropic glutamate receptor 5
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04556 PARK2; parkin [EC:2.3.2.31]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04966 TRPC3; transient receptor potential cation channel subfamily C member 3
K20719 SIGMAR1; sigma non-opioid intracellular receptor
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04961 RYR1; ryanodine receptor 1
K04962 RYR2; ryanodine receptor 2
K04963 RYR3; ryanodine receptor 3
K15840 PDYN; proenkephalin B (prodynorphin)
K11828 DLG4; discs large protein 4
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K05211 GRIN2C; glutamate receptor ionotropic, NMDA 2C
K05212 GRIN2D; glutamate receptor ionotropic, NMDA 2D
K05197 GRIA1; glutamate receptor 1
K05198 GRIA2; glutamate receptor 2
K05199 GRIA3; glutamate receptor 3
K05200 GRIA4; glutamate receptor 4
K04849 CACNA1B; voltage-dependent calcium channel N type alpha-1B
K04850 CACNA1C; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S; voltage-dependent calcium channel L type alpha-1S
K04560 STX1A; syntaxin 1A
K04809 CHRNA7; nicotinic acetylcholine receptor alpha-7
K05853 ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
K05853 ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
K05853 ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
K04505 PSEN1; presenilin 1 [EC:3.4.23.-]
K04522 PSEN2; presenilin 2 [EC:3.4.23.-]
K11519 DERL1; Derlin-1
K13525 VCP; transitional endoplasmic reticulum ATPase
K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
K04551 UBB; ubiquitin B
K08770 UBC; ubiquitin C
K02730 PSMA6; 20S proteasome subunit alpha 1 [EC:3.4.25.1]
K02726 PSMA2; 20S proteasome subunit alpha 2 [EC:3.4.25.1]
K02728 PSMA4; 20S proteasome subunit alpha 3 [EC:3.4.25.1]
K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
K02729 PSMA5; 20S proteasome subunit alpha 5 [EC:3.4.25.1]
K02725 PSMA1; 20S proteasome subunit alpha 6 [EC:3.4.25.1]
K02727 PSMA3; 20S proteasome subunit alpha 7 [EC:3.4.25.1]
K02738 PSMB6; 20S proteasome subunit beta 1 [EC:3.4.25.1]
K02739 PSMB7; 20S proteasome subunit beta 2 [EC:3.4.25.1]
K02735 PSMB3; 20S proteasome subunit beta 3 [EC:3.4.25.1]
K02734 PSMB2; 20S proteasome subunit beta 4 [EC:3.4.25.1]
K02737 PSMB5; 20S proteasome subunit beta 5 [EC:3.4.25.1]
K02732 PSMB1; 20S proteasome subunit beta 6 [EC:3.4.25.1]
K02736 PSMB4; 20S proteasome subunit beta 7 [EC:3.4.25.1]
K03061 PSMC2; 26S proteasome regulatory subunit T1
K03062 PSMC1; 26S proteasome regulatory subunit T2
K03063 PSMC4; 26S proteasome regulatory subunit T3
K03064 PSMC6; 26S proteasome regulatory subunit T4
K03065 PSMC3; 26S proteasome regulatory subunit T5
K03066 PSMC5; 26S proteasome regulatory subunit T6
K03028 PSMD2; 26S proteasome regulatory subunit N1
K03032 PSMD1; 26S proteasome regulatory subunit N2
K03033 PSMD3; 26S proteasome regulatory subunit N3
K06693 PSMD9; 26S proteasome regulatory subunit N4
K03035 PSMD12; 26S proteasome regulatory subunit N5
K03036 PSMD11; 26S proteasome regulatory subunit N6
K03037 PSMD6; 26S proteasome regulatory subunit N7
K03038 PSMD7; 26S proteasome regulatory subunit N8
K03039 PSMD13; 26S proteasome regulatory subunit N9
K03029 PSMD4; 26S proteasome regulatory subunit N10
K03030 PSMD14; 26S proteasome regulatory subunit N11
K03031 PSMD8; 26S proteasome regulatory subunit N12
K06691 RPN13; 26S proteasome regulatory subunit N13
K10881 SHFM1; 26 proteasome complex subunit DSS1
K05611 UCHL1; ubiquitin carboxyl-terminal hydrolase L1 [EC:3.4.19.12]
K03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]
K10698 UBE1L; ubiquitin-activating enzyme E1-like [EC:6.2.1.45]
K04552 UBE2L3; ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23]
K04553 UBE2L6; ubiquitin/ISG15-conjugating enzyme E2 L6 [EC:2.3.2.23]
K04554 UBE2J2; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]
K10578 UBE2J1; ubiquitin-conjugating enzyme E2 J1 [EC:2.3.2.23]
K04555 UBE2G2; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
K10575 UBE2G1; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
K04243 GPR37; prosaposin receptor
K04557 SEPT5; septin 5
K04558 SNCAIP; synphilin-1
K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
K10707 VAPB; vesicle-associated membrane protein-associated protein B
K09054 ATF6A; cyclic AMP-dependent transcription factor ATF-6 alpha
K04452 DDIT3; DNA damage-inducible transcript 3
K09027 XBP1; X box-binding protein 1
K08852 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04741 CASP12; caspase 12 [EC:3.4.22.-]
K04418 MAP3K10; mitogen-activated protein kinase kinase kinase 10 [EC:2.7.11.25]
K08860 EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K03237 EIF2S1; translation initiation factor 2 subunit 1
K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
K05036 SLC6A3; solute carrier family 6 (neurotransmitter transporter, dopamine) member 3
K05688 PINK1; PTEN induced putative kinase 1 [EC:2.7.11.1]
K03878 ND1; NADH-ubiquinone oxidoreductase chain 1 [EC:7.1.1.2]
K03879 ND2; NADH-ubiquinone oxidoreductase chain 2 [EC:7.1.1.2]
K03880 ND3; NADH-ubiquinone oxidoreductase chain 3 [EC:7.1.1.2]
K03881 ND4; NADH-ubiquinone oxidoreductase chain 4 [EC:7.1.1.2]
K03882 ND4L; NADH-ubiquinone oxidoreductase chain 4L [EC:7.1.1.2]
K03883 ND5; NADH-ubiquinone oxidoreductase chain 5 [EC:7.1.1.2]
K03884 ND6; NADH-ubiquinone oxidoreductase chain 6 [EC:7.1.1.2]
K03942 NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
K03943 NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:7.1.1.2]
K03944 NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
K03945 NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1
K03946 NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2
K03947 NDUFA3; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3
K03948 NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K03948 NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K03949 NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5
K03950 NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6
K03951 NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7
K03952 NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8
K03953 NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9
K03954 NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10
K03955 NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1, acyl-carrier protein
K03956 NDUFA11; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11
K11352 NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12
K11353 NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13
K03957 NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
K03959 NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3
K03960 NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4
K03961 NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5
K03962 NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6
K03963 NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7
K03964 NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8
K03965 NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9
K03966 NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10
K11351 NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
K03934 NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:7.1.1.2]
K03935 NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:7.1.1.2]
K03936 NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:7.1.1.2]
K03937 NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
K03938 NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5
K03939 NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6
K03940 NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:7.1.1.2]
K03941 NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:7.1.1.2]
K03967 NDUFC1; NADH dehydrogenase (ubiquinone) 1 subunit C1
K03968 NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
K03968 NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
K00234 SDHA; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
K00235 SDHB; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
K00236 SDHC; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
K00237 SDHD; succinate dehydrogenase (ubiquinone) membrane anchor subunit
K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
K00413 CYC1; ubiquinol-cytochrome c reductase cytochrome c1 subunit
K00414 QCR1; ubiquinol-cytochrome c reductase core subunit 1
K00415 QCR2; ubiquinol-cytochrome c reductase core subunit 2
K00416 QCR6; ubiquinol-cytochrome c reductase subunit 6
K00416 QCR6; ubiquinol-cytochrome c reductase subunit 6
K00417 QCR7; ubiquinol-cytochrome c reductase subunit 7
K00418 QCR8; ubiquinol-cytochrome c reductase subunit 8
K00419 QCR9; ubiquinol-cytochrome c reductase subunit 9
K00420 QCR10; ubiquinol-cytochrome c reductase subunit 10
K02262 COX3; cytochrome c oxidase subunit 3
K02256 COX1; cytochrome c oxidase subunit 1 [EC:7.1.1.9]
K02261 COX2; cytochrome c oxidase subunit 2
K02263 COX4; cytochrome c oxidase subunit 4
K02263 COX4; cytochrome c oxidase subunit 4
K02264 COX5A; cytochrome c oxidase subunit 5a
K02265 COX5B; cytochrome c oxidase subunit 5b
K02266 COX6A; cytochrome c oxidase subunit 6a
K02266 COX6A; cytochrome c oxidase subunit 6a
K02267 COX6B; cytochrome c oxidase subunit 6b
K02267 COX6B; cytochrome c oxidase subunit 6b
K02268 COX6C; cytochrome c oxidase subunit 6c
K02270 COX7A; cytochrome c oxidase subunit 7a
K02270 COX7A; cytochrome c oxidase subunit 7a
K02270 COX7A; cytochrome c oxidase subunit 7a
K02271 COX7B; cytochrome c oxidase subunit 7b
K02271 COX7B; cytochrome c oxidase subunit 7b
K02272 COX7C; cytochrome c oxidase subunit 7c
K02273 COX8; cytochrome c oxidase subunit 8
K02273 COX8; cytochrome c oxidase subunit 8
K02132 ATPeF1A; F-type H+-transporting ATPase subunit alpha
K02133 ATPeF1B; F-type H+-transporting ATPase subunit beta [EC:7.1.2.2]
K02136 ATPeF1G; F-type H+-transporting ATPase subunit gamma
K02134 ATPeF1D; F-type H+-transporting ATPase subunit delta
K02135 ATPeF1E; F-type H+-transporting ATPase subunit epsilon
K02126 ATPeF0A; F-type H+-transporting ATPase subunit a
K02127 ATPeF0B; F-type H+-transporting ATPase subunit b
K02128 ATPeF0C; F-type H+-transporting ATPase subunit c
K02128 ATPeF0C; F-type H+-transporting ATPase subunit c
K02128 ATPeF0C; F-type H+-transporting ATPase subunit c
K02138 ATPeF0D; F-type H+-transporting ATPase subunit d
K02137 ATPeF0O; F-type H+-transporting ATPase subunit O
K02131 ATPeF0F6; F-type H+-transporting ATPase subunit 6
K02125 ATPeF08; F-type H+-transporting ATPase subunit 8
K02161 BCL2; apoptosis regulator Bcl-2
K05862 VDAC1; voltage-dependent anion channel protein 1
K11518 TOM40; mitochondrial import receptor subunit TOM40
K11518 TOM40; mitochondrial import receptor subunit TOM40
K20858 MCU; calcium uniporter protein, mitochondrial
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K02158 BAD; Bcl-2-antagonist of cell death
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K08844 LRRK2; leucine-rich repeat kinase 2 [EC:2.7.11.1]
K08669 HTRA2; HtrA serine peptidase 2 [EC:3.4.21.108]
K09488 TRAP1; TNF receptor-associated protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04559 HIP1; huntingtin interacting protein 1
K04638 IFT57; intraflagellar transport protein 57
K08683 HSD17B10; 3-hydroxyacyl-CoA dehydrogenase / 3-hydroxy-2-methylbutyryl-CoA dehydrogenase [EC:1.1.1.35 1.1.1.178]
K05864 PPID; peptidyl-prolyl isomerase D [EC:5.2.1.8]
K05687 PARK7; protein DJ-1 [EC:3.5.1.124]
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K21356 MFN1; mitofusin 1 [EC:3.6.5.-]
K06030 MFN2; mitofusin 2 [EC:3.6.5.-]
K19946 OPTN; optineurin
K14381 SQSTM1; sequestosome 1
K10435 MAP1LC; microtubule-associated protein 1 light chain
K10435 MAP1LC; microtubule-associated protein 1 light chain
K10435 MAP1LC; microtubule-associated protein 1 light chain
K10435 MAP1LC; microtubule-associated protein 1 light chain
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K12650 TANK; TRAF family member-associated NF-kappa-B activator
K23610 WDR41; WD repeat-containing protein 41
K23611 SMCR8; guanine nucleotide exchange protein SMCR8
K23609 C9ORF72; guanine nucleotide exchange protein C9orf72
K07901 RAB8A; Ras-related protein Rab-8A
K07925 RAB39B; Ras-related protein Rab-39B
K07874 RAB1A; Ras-related protein Rab-1A
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K21357 ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
K08269 ULK2; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
K19730 ATG101; autophagy-related protein 101
K08331 ATG13; autophagy-related protein 13
K17589 RB1CC1; RB1-inducible coiled-coil protein 1
K17985 AMBRA1; activating molecule in BECN1-regulated autophagy protein 1
K08334 BECN; beclin
K08334 BECN; beclin
K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
K17889 ATG14L; beclin 1-associated autophagy-related key regulator
K21246 NRBF2; nuclear receptor-binding factor 2
K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
K17906 ATG2; autophagy-related protein 2
K17906 ATG2; autophagy-related protein 2
K17908 WIPI1_2; autophagy-related protein 18
K17908 WIPI1_2; autophagy-related protein 18
K17603 ZFYVE1; zinc finger FYVE domain-containing protein 1
K04575 ALS2; amyotrophic lateral sclerosis 2 protein
K07887 RAB5A; Ras-related protein Rab-5A
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K12192 CHMP2B; charged multivesicular body protein 2B
K22913 FIG4; phosphatidylinositol 3,5-bisphosphate 5-phosphatase [EC:3.1.3.-]
K19026 SPG11; spatacsin
K03156 TNF; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A
K05141 TNFRSF1B; tumor necrosis factor receptor superfamily member 1B
K02308 DAXX; death-associated protein 6
K04432 MAP2K3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K13240 NOS1; nitric-oxide synthase, brain [EC:1.14.13.39]
K04569 CCS; copper chaperone for superoxide dismutase
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K03781 katE; catalase [EC:1.11.1.6]
K07607 PRPH; peripherin
K04572 NEFL; neurofilament light polypeptide
K04573 NEF3; neurofilament medium polypeptide (neurofilament 3)
K04574 NEFH; neurofilament heavy polypeptide
K10396 KIF5; kinesin family member 5
K10396 KIF5; kinesin family member 5
K10396 KIF5; kinesin family member 5
K10407 KLC; kinesin light chain
K10407 KLC; kinesin light chain
K10407 KLC; kinesin light chain
K10407 KLC; kinesin light chain
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07375 TUBB; tubulin beta
K07375 TUBB; tubulin beta
K07375 TUBB; tubulin beta
K07375 TUBB; tubulin beta
K07375 TUBB; tubulin beta
K07375 TUBB; tubulin beta
K07375 TUBB; tubulin beta
K07375 TUBB; tubulin beta
K07375 TUBB; tubulin beta
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03115 CSNK2B; casein kinase II subunit beta
K04355 BDNF; brain-derived neurotrophic factor
K04648 DCTN1; dynactin 1
K10424 DCTN2; dynactin 2
K10425 DCTN3; dynactin 3
K10426 DCTN4; dynactin 4
K10427 DCTN5; dynactin 5
K10428 DCTN6; dynactin 6
K16575 ACTR1; centractin
K16575 ACTR1; centractin
K16576 ACTR10; actin-related protein 10
K04647 HAP1; huntingtin-associated protein 1
K10408 DNAH; dynein axonemal heavy chain
K10408 DNAH; dynein axonemal heavy chain
K10408 DNAH; dynein axonemal heavy chain
K10408 DNAH; dynein axonemal heavy chain
K10408 DNAH; dynein axonemal heavy chain
K10408 DNAH; dynein axonemal heavy chain
K10408 DNAH; dynein axonemal heavy chain
K10408 DNAH; dynein axonemal heavy chain
K10408 DNAH; dynein axonemal heavy chain
K10408 DNAH; dynein axonemal heavy chain
K10408 DNAH; dynein axonemal heavy chain
K10408 DNAH; dynein axonemal heavy chain
K10408 DNAH; dynein axonemal heavy chain
K10410 DNALI; dynein axonemal light intermediate chain 1
K10409 DNAI1; dynein axonemal intermediate chain 1
K11143 DNAI2; dynein axonemal intermediate chain 2
K10411 DNAL1; dynein axonemal light chain 1
K10412 DNAL4; dynein axonemal light chain 4
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K01367 CAPN1; calpain-1 [EC:3.4.22.52]
K03853 CAPN2; calpain-2 [EC:3.4.22.53]
K11716 CDK5R1; cyclin-dependent kinase 5 activator 1
K02090 CDK5; cyclin-dependent kinase 5 [EC:2.7.11.22]
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K02165 DKK1_2_4; dickkopf 1/2/4
K02165 DKK1_2_4; dickkopf 1/2/4
K02165 DKK1_2_4; dickkopf 1/2/4
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K02105 CTNNB1; catenin beta 1
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K19722 AGER; receptor for advanced glycosylation end products
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K08008 NOX1; NADPH oxidase 1
K21421 NOX2; NADPH oxidase 2 [EC:1.-.-.-]
K21423 NOX4; NADPH oxidase 4 [EC:1.6.3.-]
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K05405 IL6; interleukin 6
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K05453 CSF1; macrophage colony-stimulating factor 1
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09165 Substance dependence
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05030 Cocaine addiction [PATH:hsa05030]
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05031 Amphetamine addiction [PATH:hsa05031]
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05032 Morphine addiction [PATH:hsa05032]
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05033 Nicotine addiction [PATH:hsa05033]
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05034 Alcoholism [PATH:hsa05034]
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7054 TH; tyrosine hydroxylase
1644 DDC; dopa decarboxylase
6570 SLC18A1; solute carrier family 18 member A1
6571 SLC18A2; solute carrier family 18 member A2
4129 MAOB; monoamine oxidase B
4128 MAOA; monoamine oxidase A
6531 SLC6A3; solute carrier family 6 member 3
2902 GRIN1; glutamate ionotropic receptor NMDA type subunit 1
2903 GRIN2A; glutamate ionotropic receptor NMDA type subunit 2A
2904 GRIN2B; glutamate ionotropic receptor NMDA type subunit 2B
2905 GRIN2C; glutamate ionotropic receptor NMDA type subunit 2C
2906 GRIN2D; glutamate ionotropic receptor NMDA type subunit 2D
116443 GRIN3A; glutamate ionotropic receptor NMDA type subunit 3A
116444 GRIN3B; glutamate ionotropic receptor NMDA type subunit 3B
3065 HDAC1; histone deacetylase 1
3066 HDAC2; histone deacetylase 2
8841 HDAC3; histone deacetylase 3
9759 HDAC4; histone deacetylase 4
10014 HDAC5; histone deacetylase 5
10013 HDAC6; histone deacetylase 6
51564 HDAC7; histone deacetylase 7
55869 HDAC8; histone deacetylase 8
9734 HDAC9; histone deacetylase 9
83933 HDAC10; histone deacetylase 10
79885 HDAC11; histone deacetylase 11
3014 H2AX; H2A.X variant histone
8338 H2AC20; H2A clustered histone 20
85235 H2AC12; H2A clustered histone 12
221613 H2AC1; H2A clustered histone 1
92815 H2AC25; H2A clustered histone 25
83740 H2AB3; H2A.B variant histone 3
3012 H2AC8; H2A clustered histone 8
8335 H2AC4; H2A clustered histone 4
55506 MACROH2A2; macroH2A.2 histone
9555 MACROH2A1; macroH2A.1 histone
723790 H2AC19; H2A clustered histone 19
55766 H2AJ; H2A.J histone
474382 H2AB1; H2A.B variant histone 1
8336 H2AC17; H2A clustered histone 17
8337 H2AC18; H2A clustered histone 18
8969 H2AC11; H2A clustered histone 11
317772 H2AC21; H2A clustered histone 21
94239 H2AZ2; H2A.Z variant histone 2
3013 H2AC7; H2A clustered histone 7
3015 H2AZ1; H2A.Z variant histone 1
8330 H2AC15; H2A clustered histone 15
8334 H2AC6; H2A clustered histone 6
8329 H2AC13; H2A clustered histone 13
8331 H2AC14; H2A clustered histone 14
8332 H2AC16; H2A clustered histone 16
474381 H2AB2; H2A.B variant histone 2
115482686 H2AL3; H2A.L variant histone 3
8341 H2BC15; H2B clustered histone 15
8345 H2BC9; H2B clustered histone 9
8342 H2BC14; H2B clustered histone 14
158983 H2BW1; H2B.W histone 1
255626 H2BC1; H2B clustered histone 1
440689 H2BC18; H2B clustered histone 18
8348 H2BC17; H2B clustered histone 17
3018 H2BC3; H2B clustered histone 3
8339 H2BC8; H2B clustered histone 8
8340 H2BC13; H2B clustered histone 13
8347 H2BC4; H2B clustered histone 4
3017 H2BC5; H2B clustered histone 5
8344 H2BC6; H2B clustered histone 6
8346 H2BC10; H2B clustered histone 10
8349 H2BC21; H2B clustered histone 21
8970 H2BC11; H2B clustered histone 11
85236 H2BC12; H2B clustered histone 12
128312 H2BC26; H2B clustered histone 26
8343 H2BC7; H2B clustered histone 7
286436 H2BW2; H2B.W histone 2
102724334 histone H2B type F-S-like
114483833 H2BK1; H2B.K variant histone 1
54145 H2BC12L; H2B clustered histone 12 like
440093 H3-5; H3.5 histone
3021 H3-3B; H3.3 histone B
8351 H3C4; H3 clustered histone 4
8352 H3C3; H3 clustered histone 3
8350 H3C1; H3 clustered histone 1
3020 H3-3A; H3.3 histone A
8290 H3-4; H3.4 histone, cluster member
126961 H3C14; H3 clustered histone 14
333932 H3C15; H3 clustered histone 15
653604 H3C13; H3 clustered histone 13
8353 H3C6; H3 clustered histone 6
8354 H3C11; H3 clustered histone 11
8355 H3C8; H3 clustered histone 8
8356 H3C12; H3 clustered histone 12
8357 H3C10; H3 clustered histone 10
8358 H3C2; H3 clustered histone 2
8968 H3C7; H3 clustered histone 7
121504 H4C16; H4 histone 16
554313 H4C15; H4 clustered histone 15
8294 H4C9; H4 clustered histone 9
8360 H4C4; H4 clustered histone 4
8361 H4C6; H4 clustered histone 6
8362 H4C12; H4 clustered histone 12
8363 H4C11; H4 clustered histone 11
8364 H4C3; H4 clustered histone 3
8365 H4C8; H4 clustered histone 8
8366 H4C2; H4 clustered histone 2
8367 H4C5; H4 clustered histone 5
8368 H4C13; H4 clustered histone 13
8370 H4C14; H4 clustered histone 14
8359 H4C1; H4 clustered histone 1
8369 H4C7; H4 clustered histone 7
8520 HAT1; histone acetyltransferase 1
1812 DRD1; dopamine receptor D1
2778 GNAS; GNAS complex locus
1813 DRD2; dopamine receptor D2
2770 GNAI1; G protein subunit alpha i1
2773 GNAI3; G protein subunit alpha i3
2771 GNAI2; G protein subunit alpha i2
2775 GNAO1; G protein subunit alpha o1
2782 GNB1; G protein subunit beta 1
2783 GNB2; G protein subunit beta 2
2784 GNB3; G protein subunit beta 3
59345 GNB4; G protein subunit beta 4
10681 GNB5; G protein subunit beta 5
54331 GNG2; G protein subunit gamma 2
2785 GNG3; G protein subunit gamma 3
2786 GNG4; G protein subunit gamma 4
2787 GNG5; G protein subunit gamma 5
2788 GNG7; G protein subunit gamma 7
94235 GNG8; G protein subunit gamma 8
2790 GNG10; G protein subunit gamma 10
2791 GNG11; G protein subunit gamma 11
55970 GNG12; G protein subunit gamma 12
51764 GNG13; G protein subunit gamma 13
2792 GNGT1; G protein subunit gamma transducin 1
2793 GNGT2; G protein subunit gamma transducin 2
55315 SLC29A3; solute carrier family 29 member 3
2030 SLC29A1; solute carrier family 29 member 1 (Augustine blood group)
3177 SLC29A2; solute carrier family 29 member 2
135 ADORA2A; adenosine A2a receptor
136 ADORA2B; adenosine A2b receptor
111 ADCY5; adenylate cyclase 5
5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
1385 CREB1; cAMP responsive element binding protein 1
1386 ATF2; activating transcription factor 2
468 ATF4; activating transcription factor 4
10488 CREB3; cAMP responsive element binding protein 3
90993 CREB3L1; cAMP responsive element binding protein 3 like 1
64764 CREB3L2; cAMP responsive element binding protein 3 like 2
84699 CREB3L3; cAMP responsive element binding protein 3 like 3
148327 CREB3L4; cAMP responsive element binding protein 3 like 4
9586 CREB5; cAMP responsive element binding protein 5
1388 ATF6B; activating transcription factor 6 beta
1392 CRH; corticotropin releasing hormone
4852 NPY; neuropeptide Y
627 BDNF; brain derived neurotrophic factor
4915 NTRK2; neurotrophic receptor tyrosine kinase 2
6464 SHC1; SHC adaptor protein 1
25759 SHC2; SHC adaptor protein 2
53358 SHC3; SHC adaptor protein 3
399694 SHC4; SHC adaptor protein 4
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
5173 PDYN; prodynorphin
810 CALML3; calmodulin like 3
805 CALM2; calmodulin 2
808 CALM3; calmodulin 3
801 CALM1; calmodulin 1
163688 CALML6; calmodulin like 6
51806 CALML5; calmodulin like 5
91860 CALML4; calmodulin like 4
84254 CAMKK1; calcium/calmodulin dependent protein kinase kinase 1
10645 CAMKK2; calcium/calmodulin dependent protein kinase kinase 2
814 CAMK4; calcium/calmodulin dependent protein kinase IV
2354 FOSB; FosB proto-oncogene, AP-1 transcription factor subunit
84152 PPP1R1B; protein phosphatase 1 regulatory inhibitor subunit 1B
5499 PPP1CA; protein phosphatase 1 catalytic subunit alpha
5500 PPP1CB; protein phosphatase 1 catalytic subunit beta
5501 PPP1CC; protein phosphatase 1 catalytic subunit gamma
5569 PKIA; cAMP-dependent protein kinase inhibitor alpha
|
K00501 TH; tyrosine 3-monooxygenase [EC:1.14.16.2]
K01593 DDC; aromatic-L-amino-acid/L-tryptophan decarboxylase [EC:4.1.1.28 4.1.1.105]
K08155 SLC18A1_2; MFS transporter, DHA1 family, solute carrier family 18 (vesicular amine transporter), member 1/2
K08155 SLC18A1_2; MFS transporter, DHA1 family, solute carrier family 18 (vesicular amine transporter), member 1/2
K00274 MAO; monoamine oxidase [EC:1.4.3.4]
K00274 MAO; monoamine oxidase [EC:1.4.3.4]
K05036 SLC6A3; solute carrier family 6 (neurotransmitter transporter, dopamine) member 3
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K05211 GRIN2C; glutamate receptor ionotropic, NMDA 2C
K05212 GRIN2D; glutamate receptor ionotropic, NMDA 2D
K05213 GRIN3A; glutamate receptor ionotropic, NMDA 3A
K05214 GRIN3B; glutamate receptor ionotropic, NMDA 3B
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K11404 HDAC3; histone deacetylase 3 [EC:3.5.1.98]
K11406 HDAC4_5; histone deacetylase 4/5 [EC:3.5.1.98]
K11406 HDAC4_5; histone deacetylase 4/5 [EC:3.5.1.98]
K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]
K11408 HDAC7; histone deacetylase 7 [EC:3.5.1.98]
K11405 HDAC8; histone deacetylase 8 [EC:3.5.1.98]
K11409 HDAC9; histone deacetylase 9 [EC:3.5.1.98]
K18671 HDAC10; histone deacetylase 10 [EC:3.5.1.98]
K11418 HDAC11; histone deacetylase 11 [EC:3.5.1.98]
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11253 H3; histone H3
K11253 H3; histone H3
K11253 H3; histone H3
K11253 H3; histone H3
K11253 H3; histone H3
K11253 H3; histone H3
K11253 H3; histone H3
K11253 H3; histone H3
K11253 H3; histone H3
K11253 H3; histone H3
K11253 H3; histone H3
K11253 H3; histone H3
K11253 H3; histone H3
K11253 H3; histone H3
K11253 H3; histone H3
K11253 H3; histone H3
K11253 H3; histone H3
K11254 H4; histone H4
K11254 H4; histone H4
K11254 H4; histone H4
K11254 H4; histone H4
K11254 H4; histone H4
K11254 H4; histone H4
K11254 H4; histone H4
K11254 H4; histone H4
K11254 H4; histone H4
K11254 H4; histone H4
K11254 H4; histone H4
K11254 H4; histone H4
K11254 H4; histone H4
K11254 H4; histone H4
K11254 H4; histone H4
K11303 HAT1; histone acetyltransferase 1 [EC:2.3.1.48]
K04144 DRD1; dopamine receptor D1
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K04145 DRD2; dopamine receptor D2
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO; guanine nucleotide-binding protein G(o) subunit alpha
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K15014 SLC29A1_2_3; solute carrier family 29 (equilibrative nucleoside transporter), member 1/2/3
K15014 SLC29A1_2_3; solute carrier family 29 (equilibrative nucleoside transporter), member 1/2/3
K15014 SLC29A1_2_3; solute carrier family 29 (equilibrative nucleoside transporter), member 1/2/3
K04266 ADORA2A; adenosine receptor A2a
K04267 ADORA2B; adenosine receptor A2b
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B; cyclic AMP-dependent transcription factor ATF-6 beta
K05256 CRH; corticotropin-releasing hormone
K05232 NPY; neuropeptide Y
K04355 BDNF; brain-derived neurotrophic factor
K04360 NTRK2; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K15840 PDYN; proenkephalin B (prodynorphin)
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K00908 CAMKK1; calcium/calmodulin-dependent protein kinase kinase 1 [EC:2.7.11.17]
K07359 CAMKK2; calcium/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]
K05869 CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
K09029 FOSB; protein FosB
K15494 PPP1R1B; protein phosphatase 1 regulatory subunit 1B
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K15985 PKIA; cAMP-dependent protein kinase inhibitor alpha
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09166 Cardiovascular disease
|
|
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09167 Endocrine and metabolic disease
|
04930 Type II diabetes mellitus [PATH:hsa04930]
|
04940 Type I diabetes mellitus [PATH:hsa04940]
|
04950 Maturity onset diabetes of the young [PATH:hsa04950]
|
04936 Alcoholic liver disease [PATH:hsa04936]
|
04932 Non-alcoholic fatty liver disease [PATH:hsa04932]
|
04931 Insulin resistance [PATH:hsa04931]
|
04933 AGE-RAGE signaling pathway in diabetic complications [PATH:hsa04933]
|
04934 Cushing syndrome [PATH:hsa04934]
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1392 CRH; corticotropin releasing hormone
1394 CRHR1; corticotropin releasing hormone receptor 1
1395 CRHR2; corticotropin releasing hormone receptor 2
2778 GNAS; GNAS complex locus
107 ADCY1; adenylate cyclase 1
108 ADCY2; adenylate cyclase 2
109 ADCY3; adenylate cyclase 3
196883 ADCY4; adenylate cyclase 4
111 ADCY5; adenylate cyclase 5
112 ADCY6; adenylate cyclase 6
113 ADCY7; adenylate cyclase 7
114 ADCY8; adenylate cyclase 8
115 ADCY9; adenylate cyclase 9
5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
1385 CREB1; cAMP responsive element binding protein 1
1386 ATF2; activating transcription factor 2
468 ATF4; activating transcription factor 4
10488 CREB3; cAMP responsive element binding protein 3
90993 CREB3L1; cAMP responsive element binding protein 3 like 1
64764 CREB3L2; cAMP responsive element binding protein 3 like 2
84699 CREB3L3; cAMP responsive element binding protein 3 like 3
148327 CREB3L4; cAMP responsive element binding protein 3 like 4
9586 CREB5; cAMP responsive element binding protein 5
1388 ATF6B; activating transcription factor 6 beta
4221 MEN1; menin 1
9070 ASH2L; ASH2 like, histone lysine methyltransferase complex subunit
5929 RBBP5; RB binding protein 5, histone lysine methyltransferase complex subunit
11091 WDR5; WD repeat domain 5
54554 WDR5B; WD repeat domain 5B
4297 KMT2A; lysine methyltransferase 2A
8085 KMT2D; lysine methyltransferase 2D
1031 CDKN2C; cyclin dependent kinase inhibitor 2C
1030 CDKN2B; cyclin dependent kinase inhibitor 2B
1029 CDKN2A; cyclin dependent kinase inhibitor 2A
1019 CDK4; cyclin dependent kinase 4
1021 CDK6; cyclin dependent kinase 6
595 CCND1; cyclin D1
5925 RB1; RB transcriptional corepressor 1
1869 E2F1; E2F transcription factor 1
1870 E2F2; E2F transcription factor 2
1871 E2F3; E2F transcription factor 3
51655 RASD1; ras related dexamethasone induced 1
2770 GNAI1; G protein subunit alpha i1
2773 GNAI3; G protein subunit alpha i3
2771 GNAI2; G protein subunit alpha i2
196 AHR; aryl hydrocarbon receptor
23746 AIPL1; aryl hydrocarbon receptor interacting protein like 1
9049 AIP; aryl hydrocarbon receptor interacting protein
405 ARNT; aryl hydrocarbon receptor nuclear translocator
1027 CDKN1B; cyclin dependent kinase inhibitor 1B
1017 CDK2; cyclin dependent kinase 2
898 CCNE1; cyclin E1
9134 CCNE2; cyclin E2
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
775 CACNA1C; calcium voltage-gated channel subunit alpha1 C
776 CACNA1D; calcium voltage-gated channel subunit alpha1 D
778 CACNA1F; calcium voltage-gated channel subunit alpha1 F
779 CACNA1S; calcium voltage-gated channel subunit alpha1 S
815 CAMK2A; calcium/calmodulin dependent protein kinase II alpha
817 CAMK2D; calcium/calmodulin dependent protein kinase II delta
816 CAMK2B; calcium/calmodulin dependent protein kinase II beta
818 CAMK2G; calcium/calmodulin dependent protein kinase II gamma
5906 RAP1A; RAP1A, member of RAS oncogene family
5908 RAP1B; RAP1B, member of RAS oncogene family
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
3164 NR4A1; nuclear receptor subfamily 4 group A member 1
1956 EGFR; epidermal growth factor receptor
9101 USP8; ubiquitin specific peptidase 8
5443 POMC; proopiomelanocortin
4158 MC2R; melanocortin 2 receptor
56246 MRAP; melanocortin 2 receptor accessory protein
8622 PDE8B; phosphodiesterase 8B
5151 PDE8A; phosphodiesterase 8A
50940 PDE11A; phosphodiesterase 11A
2516 NR5A1; nuclear receptor subfamily 5 group A member 1
6667 SP1; Sp1 transcription factor
5087 PBX1; PBX homeobox 1
1584 CYP11B1; cytochrome P450 family 11 subfamily B member 1
1586 CYP17A1; cytochrome P450 family 17 subfamily A member 1
6770 STAR; steroidogenic acute regulatory protein
57552 NCEH1; neutral cholesterol ester hydrolase 1
79798 ARMC5; armadillo repeat containing 5
183 AGT; angiotensinogen
185 AGTR1; angiotensin II receptor type 1
2776 GNAQ; G protein subunit alpha q
2767 GNA11; G protein subunit alpha 11
23236 PLCB1; phospholipase C beta 1
5330 PLCB2; phospholipase C beta 2
5331 PLCB3; phospholipase C beta 3
5332 PLCB4; phospholipase C beta 4
3708 ITPR1; inositol 1,4,5-trisphosphate receptor type 1
3709 ITPR2; inositol 1,4,5-trisphosphate receptor type 2
3710 ITPR3; inositol 1,4,5-trisphosphate receptor type 3
3776 KCNK2; potassium two pore domain channel subfamily K member 2
8913 CACNA1G; calcium voltage-gated channel subunit alpha1 G
8912 CACNA1H; calcium voltage-gated channel subunit alpha1 H
8911 CACNA1I; calcium voltage-gated channel subunit alpha1 I
84876 ORAI1; ORAI calcium release-activated calcium modulator 1
3739 KCNA4; potassium voltage-gated channel subfamily A member 4
3777 KCNK3; potassium two pore domain channel subfamily K member 3
3949 LDLR; low density lipoprotein receptor
949 SCARB1; scavenger receptor class B member 1
1583 CYP11A1; cytochrome P450 family 11 subfamily A member 1
3283 HSD3B1; hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
3284 HSD3B2; hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
1589 CYP21A2; cytochrome P450 family 21 subfamily A member 2
2271 FH; fumarate hydratase
7471 WNT1; Wnt family member 1
7472 WNT2; Wnt family member 2
7482 WNT2B; Wnt family member 2B
7473 WNT3; Wnt family member 3
89780 WNT3A; Wnt family member 3A
54361 WNT4; Wnt family member 4
7474 WNT5A; Wnt family member 5A
81029 WNT5B; Wnt family member 5B
7475 WNT6; Wnt family member 6
7476 WNT7A; Wnt family member 7A
7477 WNT7B; Wnt family member 7B
7478 WNT8A; Wnt family member 8A
7479 WNT8B; Wnt family member 8B
7483 WNT9A; Wnt family member 9A
7484 WNT9B; Wnt family member 9B
7480 WNT10B; Wnt family member 10B
80326 WNT10A; Wnt family member 10A
7481 WNT11; Wnt family member 11
51384 WNT16; Wnt family member 16
8321 FZD1; frizzled class receptor 1
8324 FZD7; frizzled class receptor 7
2535 FZD2; frizzled class receptor 2
7976 FZD3; frizzled class receptor 3
8322 FZD4; frizzled class receptor 4
7855 FZD5; frizzled class receptor 5
8325 FZD8; frizzled class receptor 8
8323 FZD6; frizzled class receptor 6
11211 FZD10; frizzled class receptor 10
8326 FZD9; frizzled class receptor 9
1857 DVL3; dishevelled segment polarity protein 3
1856 DVL2; dishevelled segment polarity protein 2
1855 DVL1; dishevelled segment polarity protein 1
2932 GSK3B; glycogen synthase kinase 3 beta
8312 AXIN1; axin 1
8313 AXIN2; axin 2
1499 CTNNB1; catenin beta 1
324 APC; APC regulator of WNT signaling pathway
10297 APC2; APC regulator of WNT signaling pathway 2
6932 TCF7; transcription factor 7
83439 TCF7L1; transcription factor 7 like 1
6934 TCF7L2; transcription factor 7 like 2
51176 LEF1; lymphoid enhancer binding factor 1
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K05256 CRH; corticotropin-releasing hormone
K04578 CRHR1; corticotropin releasing hormone receptor 1
K04579 CRHR2; corticotropin releasing hormone receptor 2
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B; cyclic AMP-dependent transcription factor ATF-6 beta
K14970 MEN1; menin
K14964 ASH2; Set1/Ash2 histone methyltransferase complex subunit ASH2
K14961 RBBP5; COMPASS component SWD1
K14963 WDR5; COMPASS component SWD3
K14963 WDR5; COMPASS component SWD3
K09186 MLL1; [histone H3]-lysine4 N-trimethyltransferase MLL1 [EC:2.1.1.354]
K09187 MLL2; [histone H3]-lysine4 N-trimethyltransferase MLL2 [EC:2.1.1.354]
K06622 CDKN2C; cyclin-dependent kinase inhibitor 2C
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K07843 RASD1; RAS, dexamethasone-induced Ras-related protein 1
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K09093 AHR; aryl hydrocarbon receptor
K17767 AIP; AH receptor-interacting protein
K17767 AIP; AH receptor-interacting protein
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04850 CACNA1C; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S; voltage-dependent calcium channel L type alpha-1S
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04465 NR4A1; nuclear receptor subfamily 4 group A member 1
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
K05228 POMC; proopiomelanocortin
K04200 MC2R; melanocortin 2 receptor
K22398 MRAP; melanocortin-2 receptor accessory protein
K18437 PDE8; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]
K18437 PDE8; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]
K13298 PDE11; dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 [EC:3.1.4.17 3.1.4.35]
K08560 NR5A1; steroidogenic factor 1
K04684 SP1; transcription factor Sp1
K09355 PBX1; pre-B-cell leukemia transcription factor 1
K00497 CYP11B1; steroid 11beta-monooxygenase [EC:1.14.15.4]
K00512 CYP17A; steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:1.14.14.19 1.14.14.32]
K16931 STAR; steroidogenic acute regulatory protein, mitochondrial
K14349 NCEH1; neutral cholesterol ester hydrolase 1 [EC:3.1.1.-]
K22499 ARMC5; armadillo repeat-containing protein 5
K09821 AGT; angiotensinogen
K04166 AGTR1; angiotensin II receptor type 1
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04913 KCNK2; potassium channel subfamily K member 2
K04854 CACNA1G; voltage-dependent calcium channel T type alpha-1G
K04855 CACNA1H; voltage-dependent calcium channel T type alpha-1H
K04856 CACNA1I; voltage-dependent calcium channel T type alpha-1I
K16056 ORAI1; calcium release-activated calcium channel protein 1
K04877 KCNA4; potassium voltage-gated channel Shaker-related subfamily A member 4
K04914 KCNK3; potassium channel subfamily K member 3
K12473 LDLR; low-density lipoprotein receptor
K13885 SCARB1; scavenger receptor class B, member 1
K00498 CYP11A; cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
K00070 HSD3B; 3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]
K00070 HSD3B; 3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]
K00513 CYP21A; steroid 21-monooxygenase [EC:1.14.14.16]
K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02105 CTNNB1; catenin beta 1
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
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09175 Drug resistance: antimicrobial
|
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09176 Drug resistance: antineoplastic
|
01521 EGFR tyrosine kinase inhibitor resistance [PATH:hsa01521]
|
1950 EGF; epidermal growth factor
7039 TGFA; transforming growth factor alpha
1956 EGFR; epidermal growth factor receptor
2064 ERBB2; erb-b2 receptor tyrosine kinase 2
3084 NRG1; neuregulin 1
9542 NRG2; neuregulin 2
2065 ERBB3; erb-b2 receptor tyrosine kinase 3
3082 HGF; hepatocyte growth factor
4233 MET; MET proto-oncogene, receptor tyrosine kinase
3479 IGF1; insulin like growth factor 1
3480 IGF1R; insulin like growth factor 1 receptor
7422 VEGFA; vascular endothelial growth factor A
3791 KDR; kinase insert domain receptor
5154 PDGFA; platelet derived growth factor subunit A
5155 PDGFB; platelet derived growth factor subunit B
56034 PDGFC; platelet derived growth factor C
80310 PDGFD; platelet derived growth factor D
5156 PDGFRA; platelet derived growth factor receptor alpha
5159 PDGFRB; platelet derived growth factor receptor beta
2247 FGF2; fibroblast growth factor 2
2263 FGFR2; fibroblast growth factor receptor 2
2261 FGFR3; fibroblast growth factor receptor 3
2621 GAS6; growth arrest specific 6
558 AXL; AXL receptor tyrosine kinase
3569 IL6; interleukin 6
3570 IL6R; interleukin 6 receptor
3716 JAK1; Janus kinase 1
3717 JAK2; Janus kinase 2
6774 STAT3; signal transducer and activator of transcription 3
6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase
2549 GAB1; GRB2 associated binding protein 1
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
5728 PTEN; phosphatase and tensin homolog
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
2475 MTOR; mechanistic target of rapamycin kinase
6198 RPS6KB1; ribosomal protein S6 kinase B1
6199 RPS6KB2; ribosomal protein S6 kinase B2
6194 RPS6; ribosomal protein S6
1978 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
1977 EIF4E; eukaryotic translation initiation factor 4E
9470 EIF4E2; eukaryotic translation initiation factor 4E family member 2
253314 EIF4E1B; eukaryotic translation initiation factor 4E family member 1B
572 BAD; BCL2 associated agonist of cell death
2932 GSK3B; glycogen synthase kinase 3 beta
2309 FOXO3; forkhead box O3
10018 BCL2L11; BCL2 like 11
5335 PLCG1; phospholipase C gamma 1
5336 PLCG2; phospholipase C gamma 2
5578 PRKCA; protein kinase C alpha
5579 PRKCB; protein kinase C beta
5582 PRKCG; protein kinase C gamma
6464 SHC1; SHC adaptor protein 1
25759 SHC2; SHC adaptor protein 2
53358 SHC3; SHC adaptor protein 3
399694 SHC4; SHC adaptor protein 4
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
4763 NF1; neurofibromin 1
581 BAX; BCL2 associated X, apoptosis regulator
598 BCL2L1; BCL2 like 1
596 BCL2; BCL2 apoptosis regulator
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K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05455 NRG1; neuregulin 1
K05456 NRG2; neuregulin 2
K05084 ERBB3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K05460 HGF; hepatocyte growth factor
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K05448 VEGFA; vascular endothelial growth factor A
K05098 KDR; kinase insert domain protein receptor [EC:2.7.10.1]
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05450 PDGFC_D; platelet derived growth factor C/D
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K18497 FGF2; fibroblast growth factor 2
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05464 GAS6; growth arrest-specific 6
K05115 AXL; AXL receptor tyrosine kinase [EC:2.7.10.1]
K05405 IL6; interleukin 6
K05055 IL6R; interleukin 6 receptor
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K09593 GAB1; GRB2-associated-binding protein 1
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02991 RP-S6e; small subunit ribosomal protein S6e
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K03259 EIF4E; translation initiation factor 4E
K03259 EIF4E; translation initiation factor 4E
K03259 EIF4E; translation initiation factor 4E
K02158 BAD; Bcl-2-antagonist of cell death
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K09408 FOXO3; forkhead box protein O3
K16341 BCL2L11; Bcl-2-like protein 11
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K08052 NF1; neurofibromin 1
K02159 BAX; apoptosis regulator BAX
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
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01524 Platinum drug resistance [PATH:hsa01524]
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01523 Antifolate resistance [PATH:hsa01523]
|
01522 Endocrine resistance [PATH:hsa01522]
|
1565 CYP2D6; cytochrome P450 family 2 subfamily D member 6
107987478 cytochrome P450 2D6-like
1564 CYP2D7; cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)
107987479 CYP2D6; cytochrome P450 2D6
8647 ABCB11; ATP binding cassette subfamily B member 11
2099 ESR1; estrogen receptor 1
2100 ESR2; estrogen receptor 2
8202 NCOA3; nuclear receptor coactivator 3
5469 MED1; mediator complex subunit 1
10498 CARM1; coactivator associated arginine methyltransferase 1
2353 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
6667 SP1; Sp1 transcription factor
9611 NCOR1; nuclear receptor corepressor 1
2852 GPER1; G protein-coupled estrogen receptor 1
2778 GNAS; GNAS complex locus
6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase
4313 MMP2; matrix metallopeptidase 2
4318 MMP9; matrix metallopeptidase 9
1839 HBEGF; heparin binding EGF like growth factor
107 ADCY1; adenylate cyclase 1
108 ADCY2; adenylate cyclase 2
109 ADCY3; adenylate cyclase 3
196883 ADCY4; adenylate cyclase 4
111 ADCY5; adenylate cyclase 5
112 ADCY6; adenylate cyclase 6
113 ADCY7; adenylate cyclase 7
114 ADCY8; adenylate cyclase 8
115 ADCY9; adenylate cyclase 9
5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
1956 EGFR; epidermal growth factor receptor
2064 ERBB2; erb-b2 receptor tyrosine kinase 2
3479 IGF1; insulin like growth factor 1
3480 IGF1R; insulin like growth factor 1 receptor
6464 SHC1; SHC adaptor protein 1
25759 SHC2; SHC adaptor protein 2
53358 SHC3; SHC adaptor protein 3
399694 SHC4; SHC adaptor protein 4
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
2475 MTOR; mechanistic target of rapamycin kinase
6198 RPS6KB1; ribosomal protein S6 kinase B1
6199 RPS6KB2; ribosomal protein S6 kinase B2
5747 PTK2; protein tyrosine kinase 2
5600 MAPK11; mitogen-activated protein kinase 11
6300 MAPK12; mitogen-activated protein kinase 12
5603 MAPK13; mitogen-activated protein kinase 13
1432 MAPK14; mitogen-activated protein kinase 14
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
596 BCL2; BCL2 apoptosis regulator
581 BAX; BCL2 associated X, apoptosis regulator
572 BAD; BCL2 associated agonist of cell death
638 BIK; BCL2 interacting killer
182 JAG1; jagged canonical Notch ligand 1
3714 JAG2; jagged canonical Notch ligand 2
10683 DLL3; delta like canonical Notch ligand 3
28514 DLL1; delta like canonical Notch ligand 1
54567 DLL4; delta like canonical Notch ligand 4
4851 NOTCH1; notch receptor 1
4853 NOTCH2; notch receptor 2
4854 NOTCH3; notch receptor 3
4855 NOTCH4; notch receptor 4
595 CCND1; cyclin D1
1019 CDK4; cyclin dependent kinase 4
5925 RB1; RB transcriptional corepressor 1
1869 E2F1; E2F transcription factor 1
1870 E2F2; E2F transcription factor 2
1871 E2F3; E2F transcription factor 3
4193 MDM2; MDM2 proto-oncogene
7157 TP53; tumor protein p53
1029 CDKN2A; cyclin dependent kinase inhibitor 2A
1031 CDKN2C; cyclin dependent kinase inhibitor 2C
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
1027 CDKN1B; cyclin dependent kinase inhibitor 1B
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K17712 CYP2D6; cytochrome P450 family 2 subfamily D6 [EC:1.14.14.1]
K17712 CYP2D6; cytochrome P450 family 2 subfamily D6 [EC:1.14.14.1]
K17712 CYP2D6; cytochrome P450 family 2 subfamily D6 [EC:1.14.14.1]
K17712 CYP2D6; cytochrome P450 family 2 subfamily D6 [EC:1.14.14.1]
K05664 ABCB11; ATP-binding cassette, subfamily B (MDR/TAP), member 11
K08550 ESR1; estrogen receptor alpha
K08551 ESR2; estrogen receptor beta
K11256 NCOA3; nuclear receptor coactivator 3 [EC:2.3.1.48]
K15144 MED1; mediator of RNA polymerase II transcription subunit 1
K05931 CARM1; type I protein arginine methyltransferase [EC:2.1.1.319]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K04684 SP1; transcription factor Sp1
K04650 NCOR1; nuclear receptor co-repressor 1
K04246 GPER1; G-protein coupled estrogen receptor 1
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K08523 HBEGF; heparin-binding EGF-like growth factor
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K02161 BCL2; apoptosis regulator Bcl-2
K02159 BAX; apoptosis regulator BAX
K02158 BAD; Bcl-2-antagonist of cell death
K18452 BIK; Bcl-2-interacting killer
K06052 JAG1; jagged-1
K21635 JAG2; jagged-2
K06051 DLL; delta
K06051 DLL; delta
K06051 DLL; delta
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K04503 CCND1; G1/S-specific cyclin-D1
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K06622 CDKN2C; cyclin-dependent kinase inhibitor 2C
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
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09180 Brite Hierarchies
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09181 Protein families: metabolism
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01000 Enzymes [BR:hsa01000]
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01001 Protein kinases [BR:hsa01001]
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5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
5613 PRKX; protein kinase cAMP-dependent X-linked catalytic subunit
5592 PRKG1; protein kinase cGMP-dependent 1
5593 PRKG2; protein kinase cGMP-dependent 2
5578 PRKCA; protein kinase C alpha
5579 PRKCB; protein kinase C beta
5582 PRKCG; protein kinase C gamma
5580 PRKCD; protein kinase C delta
5581 PRKCE; protein kinase C epsilon
5583 PRKCH; protein kinase C eta
5588 PRKCQ; protein kinase C theta
5590 PRKCZ; protein kinase C zeta
5584 PRKCI; protein kinase C iota
5585 PKN1; protein kinase N1
5586 PKN2; protein kinase N2
29941 PKN3; protein kinase N3
6790 AURKA; aurora kinase A
9212 AURKB; aurora kinase B
6795 AURKC; aurora kinase C
5170 PDPK1; 3-phosphoinositide dependent protein kinase 1
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
6446 SGK1; serum/glucocorticoid regulated kinase 1
10110 SGK2; serum/glucocorticoid regulated kinase 2
23678 SGK3; serum/glucocorticoid regulated kinase family member 3
100533105 C8orf44-SGK3; C8orf44-SGK3 readthrough
6197 RPS6KA3; ribosomal protein S6 kinase A3
6195 RPS6KA1; ribosomal protein S6 kinase A1
6196 RPS6KA2; ribosomal protein S6 kinase A2
27330 RPS6KA6; ribosomal protein S6 kinase A6
8986 RPS6KA4; ribosomal protein S6 kinase A4
9252 RPS6KA5; ribosomal protein S6 kinase A5
6198 RPS6KB1; ribosomal protein S6 kinase B1
6199 RPS6KB2; ribosomal protein S6 kinase B2
26750 RPS6KC1; ribosomal protein S6 kinase C1
83694 RPS6KL1; ribosomal protein S6 kinase like 1
11329 STK38; serine/threonine kinase 38
23012 STK38L; serine/threonine kinase 38 like
26524 LATS2; large tumor suppressor kinase 2
9113 LATS1; large tumor suppressor kinase 1
22983 MAST1; microtubule associated serine/threonine kinase 1
23031 MAST3; microtubule associated serine/threonine kinase 3
23139 MAST2; microtubule associated serine/threonine kinase 2
375449 MAST4; microtubule associated serine/threonine kinase family member 4
84930 MASTL; microtubule associated serine/threonine kinase like
202374 STK32A; serine/threonine kinase 32A
282974 STK32C; serine/threonine kinase 32C
55351 STK32B; serine/threonine kinase 32B
1760 DMPK; DM1 protein kinase
6093 ROCK1; Rho associated coiled-coil containing protein kinase 1
9475 ROCK2; Rho associated coiled-coil containing protein kinase 2
8476 CDC42BPA; CDC42 binding protein kinase alpha
9578 CDC42BPB; CDC42 binding protein kinase beta
55561 CDC42BPG; CDC42 binding protein kinase gamma
11113 CIT; citron rho-interacting serine/threonine kinase
131890 GRK7; G protein-coupled receptor kinase 7
6011 GRK1; G protein-coupled receptor kinase 1
156 GRK2; G protein-coupled receptor kinase 2
157 GRK3; G protein-coupled receptor kinase 3
2868 GRK4; G protein-coupled receptor kinase 4
2869 GRK5; G protein-coupled receptor kinase 5
2870 GRK6; G protein-coupled receptor kinase 6
124923 RSKR; ribosomal protein S6 kinase related
57118 CAMK1D; calcium/calmodulin dependent protein kinase ID
57172 CAMK1G; calcium/calmodulin dependent protein kinase IG
8536 CAMK1; calcium/calmodulin dependent protein kinase I
814 CAMK4; calcium/calmodulin dependent protein kinase IV
139728 PNCK; pregnancy up-regulated nonubiquitous CaM kinase
79012 CAMKV; CaM kinase like vesicle associated
815 CAMK2A; calcium/calmodulin dependent protein kinase II alpha
817 CAMK2D; calcium/calmodulin dependent protein kinase II delta
816 CAMK2B; calcium/calmodulin dependent protein kinase II beta
818 CAMK2G; calcium/calmodulin dependent protein kinase II gamma
84446 BRSK1; BR serine/threonine kinase 1
9024 BRSK2; BR serine/threonine kinase 2
1111 CHEK1; checkpoint kinase 1
30811 HUNK; hormonally up-regulated Neu-associated kinase
2011 MARK2; microtubule affinity regulating kinase 2
4139 MARK1; microtubule affinity regulating kinase 1
4140 MARK3; microtubule affinity regulating kinase 3
57787 MARK4; microtubule affinity regulating kinase 4
9833 MELK; maternal embryonic leucine zipper kinase
167359 NIM1K; NIM1 serine/threonine protein kinase
81788 NUAK2; NUAK family kinase 2
9891 NUAK1; NUAK family kinase 1
23178 PASK; PAS domain containing serine/threonine kinase
5562 PRKAA1; protein kinase AMP-activated catalytic subunit alpha 1
5563 PRKAA2; protein kinase AMP-activated catalytic subunit alpha 2
102724428 SIK; salt inducible kinase 1B (putative)
150094 SIK1; salt inducible kinase 1
23235 SIK2; salt inducible kinase 2
23387 SIK3; SIK family kinase 3
54861 SNRK; SNF related kinase
6794 STK11; serine/threonine kinase 11
1612 DAPK1; death associated protein kinase 1
1613 DAPK3; death associated protein kinase 3
23604 DAPK2; death associated protein kinase 2
9262 STK17B; serine/threonine kinase 17b
9263 STK17A; serine/threonine kinase 17a
166614 DCLK2; doublecortin like kinase 2
9201 DCLK1; doublecortin like kinase 1
85443 DCLK3; doublecortin like kinase 3
9261 MAPKAPK2; MAPK activated protein kinase 2
7867 MAPKAPK3; MAPK activated protein kinase 3
8550 MAPKAPK5; MAPK activated protein kinase 5
8569 MKNK1; MAPK interacting serine/threonine kinase 1
2872 MKNK2; MAPK interacting serine/threonine kinase 2
4638 MYLK; myosin light chain kinase
85366 MYLK2; myosin light chain kinase 2
91807 MYLK3; myosin light chain kinase 3
340156 MYLK4; myosin light chain kinase family member 4
7273 TTN; titin
5260 PHKG1; phosphorylase kinase catalytic subunit gamma 1
5261 PHKG2; phosphorylase kinase catalytic subunit gamma 2
5292 PIM1; Pim-1 proto-oncogene, serine/threonine kinase
11040 PIM2; Pim-2 proto-oncogene, serine/threonine kinase
415116 PIM3; Pim-3 proto-oncogene, serine/threonine kinase
5587 PRKD1; protein kinase D1
23683 PRKD3; protein kinase D3
25865 PRKD2; protein kinase D2
5681 PSKH1; protein serine kinase H1
85481 PSKH2; protein serine kinase H2
11200 CHEK2; checkpoint kinase 2
10290 SPEG; striated muscle enriched protein kinase
7204 TRIO; trio Rho guanine nucleotide exchange factor
8997 KALRN; kalirin RhoGEF kinase
84033 OBSCN; obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
81629 TSSK3; testis specific serine kinase 3
83942 TSSK1B; testis specific serine kinase 1B
83983 TSSK6; testis specific serine kinase 6
23617 TSSK2; testis specific serine kinase 2
283629 TSSK4; testis specific serine kinase 4
8573 CASK; calcium/calmodulin dependent serine protein kinase
10221 TRIB1; tribbles pseudokinase 1
28951 TRIB2; tribbles pseudokinase 2
57761 TRIB3; tribbles pseudokinase 3
65975 STK33; serine/threonine kinase 33
83931 STK40; serine/threonine kinase 40
122011 CSNK1A1L; casein kinase 1 alpha 1 like
1452 CSNK1A1; casein kinase 1 alpha 1
1455 CSNK1G2; casein kinase 1 gamma 2
1456 CSNK1G3; casein kinase 1 gamma 3
53944 CSNK1G1; casein kinase 1 gamma 1
1453 CSNK1D; casein kinase 1 delta
1454 CSNK1E; casein kinase 1 epsilon
102800317 TPTEP2-CSNK1E; TPTEP2-CSNK1E readthrough
146057 TTBK2; tau tubulin kinase 2
84630 TTBK1; tau tubulin kinase 1
51231 VRK3; VRK serine/threonine kinase 3
7443 VRK1; VRK serine/threonine kinase 1
7444 VRK2; VRK serine/threonine kinase 2
23552 CDK20; cyclin dependent kinase 20
728642 CDK11A; cyclin dependent kinase 11A
984 CDK11B; cyclin dependent kinase 11B
983 CDK1; cyclin dependent kinase 1
1017 CDK2; cyclin dependent kinase 2
1018 CDK3; cyclin dependent kinase 3
1019 CDK4; cyclin dependent kinase 4
1020 CDK5; cyclin dependent kinase 5
1021 CDK6; cyclin dependent kinase 6
1022 CDK7; cyclin dependent kinase 7
1024 CDK8; cyclin dependent kinase 8
23097 CDK19; cyclin dependent kinase 19
1025 CDK9; cyclin dependent kinase 9
8558 CDK10; cyclin dependent kinase 10
51755 CDK12; cyclin dependent kinase 12
8621 CDK13; cyclin dependent kinase 13
5218 CDK14; cyclin dependent kinase 14
65061 CDK15; cyclin dependent kinase 15
5127 CDK16; cyclin dependent kinase 16
5128 CDK17; cyclin dependent kinase 17
5129 CDK18; cyclin dependent kinase 18
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
5596 MAPK4; mitogen-activated protein kinase 4
5597 MAPK6; mitogen-activated protein kinase 6
5598 MAPK7; mitogen-activated protein kinase 7
225689 MAPK15; mitogen-activated protein kinase 15
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
5600 MAPK11; mitogen-activated protein kinase 11
6300 MAPK12; mitogen-activated protein kinase 12
5603 MAPK13; mitogen-activated protein kinase 13
1432 MAPK14; mitogen-activated protein kinase 14
51701 NLK; nemo like kinase
2931 GSK3A; glycogen synthase kinase 3 alpha
2932 GSK3B; glycogen synthase kinase 3 beta
57396 CLK4; CDC like kinase 4
1195 CLK1; CDC like kinase 1
1196 CLK2; CDC like kinase 2
1198 CLK3; CDC like kinase 3
344387 CDKL4; cyclin dependent kinase like 4
51265 CDKL3; cyclin dependent kinase like 3
6792 CDKL5; cyclin dependent kinase like 5
8814 CDKL1; cyclin dependent kinase like 1
8999 CDKL2; cyclin dependent kinase like 2
1859 DYRK1A; dual specificity tyrosine phosphorylation regulated kinase 1A
9149 DYRK1B; dual specificity tyrosine phosphorylation regulated kinase 1B
8445 DYRK2; dual specificity tyrosine phosphorylation regulated kinase 2
8444 DYRK3; dual specificity tyrosine phosphorylation regulated kinase 3
8798 DYRK4; dual specificity tyrosine phosphorylation regulated kinase 4
10114 HIPK3; homeodomain interacting protein kinase 3
204851 HIPK1; homeodomain interacting protein kinase 1
28996 HIPK2; homeodomain interacting protein kinase 2
147746 HIPK4; homeodomain interacting protein kinase 4
8899 PRP4K; pre-mRNA processing factor kinase PRP4K
22858 CILK1; ciliogenesis associated kinase 1
4117 MAK; male germ cell associated kinase
5891 MOK; MOK protein kinase
6732 SRPK1; SRSF protein kinase 1
6733 SRPK2; SRSF protein kinase 2
26576 SRPK3; SRSF protein kinase 3
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5606 MAP2K3; mitogen-activated protein kinase kinase 3
6416 MAP2K4; mitogen-activated protein kinase kinase 4
5607 MAP2K5; mitogen-activated protein kinase kinase 5
5608 MAP2K6; mitogen-activated protein kinase kinase 6
5609 MAP2K7; mitogen-activated protein kinase kinase 7
11184 MAP4K1; mitogen-activated protein kinase kinase kinase kinase 1
5871 MAP4K2; mitogen-activated protein kinase kinase kinase kinase 2
8491 MAP4K3; mitogen-activated protein kinase kinase kinase kinase 3
9448 MAP4K4; mitogen-activated protein kinase kinase kinase kinase 4
11183 MAP4K5; mitogen-activated protein kinase kinase kinase kinase 5
50488 MINK1; misshapen like kinase 1
23043 TNIK; TRAF2 and NCK interacting kinase
203447 NRK; Nik related kinase
140469 MYO3B; myosin IIIB
53904 MYO3A; myosin IIIA
9943 OXSR1; oxidative stress responsive kinase 1
27347 STK39; serine/threonine kinase 39
5058 PAK1; p21 (RAC1) activated kinase 1
5062 PAK2; p21 (RAC1) activated kinase 2
5063 PAK3; p21 (RAC1) activated kinase 3
10298 PAK4; p21 (RAC1) activated kinase 4
57144 PAK5; p21 (RAC1) activated kinase 5
56924 PAK6; p21 (RAC1) activated kinase 6
106821730 BUB1B-PAK6; BUB1B-PAK6 readthrough
9748 SLK; STE20 like kinase
6793 STK10; serine/threonine kinase 10
92335 STRADA; STE20 related adaptor alpha
55437 STRADB; STE20 related adaptor beta
6788 STK3; serine/threonine kinase 3
6789 STK4; serine/threonine kinase 4
8428 STK24; serine/threonine kinase 24
10494 STK25; serine/threonine kinase 25
51765 STK26; serine/threonine kinase 26
9344 TAOK2; TAO kinase 2
51347 TAOK3; TAO kinase 3
57551 TAOK1; TAO kinase 1
4214 MAP3K1; mitogen-activated protein kinase kinase kinase 1
10746 MAP3K2; mitogen-activated protein kinase kinase kinase 2
4215 MAP3K3; mitogen-activated protein kinase kinase kinase 3
4216 MAP3K4; mitogen-activated protein kinase kinase kinase 4
4217 MAP3K5; mitogen-activated protein kinase kinase kinase 5
9064 MAP3K6; mitogen-activated protein kinase kinase kinase 6
389840 MAP3K15; mitogen-activated protein kinase kinase kinase 15
80122 MAP3K19; mitogen-activated protein kinase kinase kinase 19
1326 MAP3K8; mitogen-activated protein kinase kinase kinase 8
9020 MAP3K14; mitogen-activated protein kinase kinase kinase 14
3654 IRAK1; interleukin 1 receptor associated kinase 1
3656 IRAK2; interleukin 1 receptor associated kinase 2
11213 IRAK3; interleukin 1 receptor associated kinase 3
51135 IRAK4; interleukin 1 receptor associated kinase 4
3984 LIMK1; LIM domain kinase 1
3985 LIMK2; LIM domain kinase 2
7016 TESK1; testis associated actin remodelling kinase 1
10420 TESK2; testis associated actin remodelling kinase 2
79705 LRRK1; leucine rich repeat kinase 1
120892 LRRK2; leucine rich repeat kinase 2
6885 MAP3K7; mitogen-activated protein kinase kinase kinase 7
4293 MAP3K9; mitogen-activated protein kinase kinase kinase 9
4294 MAP3K10; mitogen-activated protein kinase kinase kinase 10
4296 MAP3K11; mitogen-activated protein kinase kinase kinase 11
84451 MAP3K21; mitogen-activated protein kinase kinase kinase 21
51776 MAP3K20; mitogen-activated protein kinase kinase kinase 20
7786 MAP3K12; mitogen-activated protein kinase kinase kinase 12
9175 MAP3K13; mitogen-activated protein kinase kinase kinase 13
100526835 FPGT-TNNI3K; FPGT-TNNI3K readthrough
51086 TNNI3K; TNNI3 interacting kinase
3611 ILK; integrin linked kinase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
8844 KSR1; kinase suppressor of ras 1
283455 KSR2; kinase suppressor of ras 2
8737 RIPK1; receptor interacting serine/threonine kinase 1
8767 RIPK2; receptor interacting serine/threonine kinase 2
11035 RIPK3; receptor interacting serine/threonine kinase 3
54101 RIPK4; receptor interacting serine/threonine kinase 4
255239 ANKK1; ankyrin repeat and kinase domain containing 1
197259 MLKL; mixed lineage kinase domain like pseudokinase
4881 NPR1; natriuretic peptide receptor 1
4882 NPR2; natriuretic peptide receptor 2
2984 GUCY2C; guanylate cyclase 2C
3000 GUCY2D; guanylate cyclase 2D, retinal
2986 GUCY2F; guanylate cyclase 2F, retinal
699 BUB1; BUB1 mitotic checkpoint serine/threonine kinase
701 BUB1B; BUB1 mitotic checkpoint serine/threonine kinase B
112858 TP53RK; TP53 regulating kinase
84254 CAMKK1; calcium/calmodulin dependent protein kinase kinase 1
10645 CAMKK2; calcium/calmodulin dependent protein kinase kinase 2
8317 CDC7; cell division cycle 7
1457 CSNK2A1; casein kinase 2 alpha 1
1459 CSNK2A2; casein kinase 2 alpha 2
283106 CSNK2A3; casein kinase 2 alpha 3
83903 HASPIN; histone H3 associated protein kinase
1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
9641 IKBKE; inhibitor of nuclear factor kappa B kinase subunit epsilon
29110 TBK1; TANK binding kinase 1
2081 ERN1; endoplasmic reticulum to nucleus signaling 1
10595 ERN2; endoplasmic reticulum to nucleus signaling 2
4342 MOS; MOS proto-oncogene, serine/threonine kinase
22848 AAK1; AP2 associated kinase 1
55589 BMP2K; BMP2 inducible kinase
2580 GAK; cyclin G associated kinase
8576 STK16; serine/threonine kinase 16
341676 NEK5; NIMA related kinase 5
4750 NEK1; NIMA related kinase 1
6787 NEK4; NIMA related kinase 4
4751 NEK2; NIMA related kinase 2
4752 NEK3; NIMA related kinase 3
10783 NEK6; NIMA related kinase 6
140609 NEK7; NIMA related kinase 7
284086 NEK8; NIMA related kinase 8
91754 NEK9; NIMA related kinase 9
152110 NEK10; NIMA related kinase 10
79858 NEK11; NIMA related kinase 11
388228 SBK1; SH3 domain binding kinase 1
646643 SBK2; SH3 domain binding kinase family member 2
100130827 SBK3; SH3 domain binding kinase family member 3
65018 PINK1; PTEN induced kinase 1
157285 PRAG1; PEAK1 related, kinase-activating pseudokinase 1
79834 PEAK1; pseudopodium enriched atypical kinase 1
140901 STK35; serine/threonine kinase 35
149420 PDIK1L; PDLIM1 interacting kinase 1 like
56155 TEX14; testis expressed 14, intercellular bridge forming factor
29959 NRBP1; nuclear receptor binding protein 1
340371 NRBP2; nuclear receptor binding protein 2
27102 EIF2AK1; eukaryotic translation initiation factor 2 alpha kinase 1
5610 EIF2AK2; eukaryotic translation initiation factor 2 alpha kinase 2
9451 EIF2AK3; eukaryotic translation initiation factor 2 alpha kinase 3
440275 EIF2AK4; eukaryotic translation initiation factor 2 alpha kinase 4
5347 PLK1; polo like kinase 1
10769 PLK2; polo like kinase 2
1263 PLK3; polo like kinase 3
10733 PLK4; polo like kinase 4
57410 SCYL1; SCY1 like pseudokinase 1
55681 SCYL2; SCY1 like pseudokinase 2
57147 SCYL3; SCY1 like pseudokinase 3
54899 PXK; PX domain containing serine/threonine kinase like
93627 TBCK; TBC1 domain containing kinase
11011 TLK2; tousled like kinase 2
9874 TLK1; tousled like kinase 1
55872 PBK; PDZ binding kinase
7272 TTK; TTK protein kinase
27148 STK36; serine/threonine kinase 36
8408 ULK1; unc-51 like autophagy activating kinase 1
9706 ULK2; unc-51 like autophagy activating kinase 2
25989 ULK3; unc-51 like kinase 3
54986 ULK4; unc-51 like kinase 4
30849 PIK3R4; phosphoinositide-3-kinase regulatory subunit 4
9088 PKMYT1; protein kinase, membrane associated tyrosine/threonine 1
7465 WEE1; WEE1 G2 checkpoint kinase
494551 WEE2; WEE2 oocyte meiosis inhibiting kinase
65125 WNK1; WNK lysine deficient protein kinase 1
65266 WNK4; WNK lysine deficient protein kinase 4
65267 WNK3; WNK lysine deficient protein kinase 3
65268 WNK2; WNK lysine deficient protein kinase 2
203054 ADCK5; aarF domain containing kinase 5
56997 COQ8A; coenzyme Q8A
57143 ADCK1; aarF domain containing kinase 1
79934 COQ8B; coenzyme Q8B
90956 ADCK2; aarF domain containing kinase 2
115701 ALPK2; alpha kinase 2
57538 ALPK3; alpha kinase 3
80216 ALPK1; alpha kinase 1
140803 TRPM6; transient receptor potential cation channel subfamily M member 6
54822 TRPM7; transient receptor potential cation channel subfamily M member 7
29904 EEF2K; eukaryotic elongation factor 2 kinase
613 BCR; BCR activator of RhoGEF and GTPase
6046 BRD2; bromodomain containing 2
8019 BRD3; bromodomain containing 3
23476 BRD4; bromodomain containing 4
676 BRDT; bromodomain testis associated
10922 FASTK; Fas activated serine/threonine kinase
8859 STK19; serine/threonine kinase 19
26353 HSPB8; heat shock protein family B (small) member 8
5163 PDK1; pyruvate dehydrogenase kinase 1
5164 PDK2; pyruvate dehydrogenase kinase 2
5165 PDK3; pyruvate dehydrogenase kinase 3
5166 PDK4; pyruvate dehydrogenase kinase 4
10295 BCKDK; branched chain keto acid dehydrogenase kinase
472 ATM; ATM serine/threonine kinase
545 ATR; ATR serine/threonine kinase
2475 MTOR; mechanistic target of rapamycin kinase
5591 PRKDC; protein kinase, DNA-activated, catalytic subunit
23049 SMG1; SMG1 nonsense mediated mRNA decay associated PI3K related kinase
8295 TRRAP; transformation/transcription domain associated protein
83732 RIOK1; RIO kinase 1
55781 RIOK2; RIO kinase 2
8780 RIOK3; RIO kinase 3
6872 TAF1; TATA-box binding protein associated factor 1
138474 TAF1L; TATA-box binding protein associated factor 1 like
4261 CIITA; class II major histocompatibility complex transactivator
8805 TRIM24; tripartite motif containing 24
10155 TRIM28; tripartite motif containing 28
51592 TRIM33; tripartite motif containing 33
127933 UHMK1; U2AF homology motif kinase 1
9730 DCAF1; DDB1 and CUL4 associated factor 1
56164 STK31; serine/threonine kinase 31
84197 POMK; protein O-mannose kinase
25778 DSTYK; dual serine/threonine and tyrosine protein kinase
169436 STKLD1; serine/threonine kinase like domain containing 1
90 ACVR1; activin A receptor type 1
94 ACVRL1; activin A receptor like type 1
91 ACVR1B; activin A receptor type 1B
130399 ACVR1C; activin A receptor type 1C
657 BMPR1A; bone morphogenetic protein receptor type 1A
658 BMPR1B; bone morphogenetic protein receptor type 1B
7046 TGFBR1; transforming growth factor beta receptor 1
92 ACVR2A; activin A receptor type 2A
93 ACVR2B; activin A receptor type 2B
269 AMHR2; anti-Mullerian hormone receptor type 2
659 BMPR2; bone morphogenetic protein receptor type 2
7048 TGFBR2; transforming growth factor beta receptor 2
1956 EGFR; epidermal growth factor receptor
2064 ERBB2; erb-b2 receptor tyrosine kinase 2
2065 ERBB3; erb-b2 receptor tyrosine kinase 3
2066 ERBB4; erb-b2 receptor tyrosine kinase 4
3645 INSRR; insulin receptor related receptor
3643 INSR; insulin receptor
3480 IGF1R; insulin like growth factor 1 receptor
5156 PDGFRA; platelet derived growth factor receptor alpha
5159 PDGFRB; platelet derived growth factor receptor beta
1436 CSF1R; colony stimulating factor 1 receptor
3815 KIT; KIT proto-oncogene, receptor tyrosine kinase
2322 FLT3; fms related receptor tyrosine kinase 3
2260 FGFR1; fibroblast growth factor receptor 1
2263 FGFR2; fibroblast growth factor receptor 2
2261 FGFR3; fibroblast growth factor receptor 3
2264 FGFR4; fibroblast growth factor receptor 4
2321 FLT1; fms related receptor tyrosine kinase 1
2324 FLT4; fms related receptor tyrosine kinase 4
3791 KDR; kinase insert domain receptor
4233 MET; MET proto-oncogene, receptor tyrosine kinase
4486 MST1R; macrophage stimulating 1 receptor
4914 NTRK1; neurotrophic receptor tyrosine kinase 1
4915 NTRK2; neurotrophic receptor tyrosine kinase 2
4916 NTRK3; neurotrophic receptor tyrosine kinase 3
2041 EPHA1; EPH receptor A1
1969 EPHA2; EPH receptor A2
2042 EPHA3; EPH receptor A3
2043 EPHA4; EPH receptor A4
2044 EPHA5; EPH receptor A5
285220 EPHA6; EPH receptor A6
2045 EPHA7; EPH receptor A7
2046 EPHA8; EPH receptor A8
284656 EPHA10; EPH receptor A10
2047 EPHB1; EPH receptor B1
2048 EPHB2; EPH receptor B2
2049 EPHB3; EPH receptor B3
2050 EPHB4; EPH receptor B4
2051 EPHB6; EPH receptor B6
558 AXL; AXL receptor tyrosine kinase
7301 TYRO3; TYRO3 protein tyrosine kinase
10461 MERTK; MER proto-oncogene, tyrosine kinase
238 ALK; ALK receptor tyrosine kinase
4058 LTK; leukocyte receptor tyrosine kinase
7075 TIE1; tyrosine kinase with immunoglobulin like and EGF like domains 1
7010 TEK; TEK receptor tyrosine kinase
4919 ROR1; receptor tyrosine kinase like orphan receptor 1
4920 ROR2; receptor tyrosine kinase like orphan receptor 2
780 DDR1; discoidin domain receptor tyrosine kinase 1
4921 DDR2; discoidin domain receptor tyrosine kinase 2
5979 RET; ret proto-oncogene
6098 ROS1; ROS proto-oncogene 1, receptor tyrosine kinase
5754 PTK7; protein tyrosine kinase 7 (inactive)
6259 RYK; receptor like tyrosine kinase
4593 MUSK; muscle associated receptor tyrosine kinase
9625 AATK; apoptosis associated tyrosine kinase
22853 LMTK2; lemur tyrosine kinase 2
114783 LMTK3; lemur tyrosine kinase 3
25 ABL1; ABL proto-oncogene 1, non-receptor tyrosine kinase
27 ABL2; ABL proto-oncogene 2, non-receptor tyrosine kinase
8711 TNK1; tyrosine kinase non receptor 1
10188 TNK2; tyrosine kinase non receptor 2
1445 CSK; C-terminal Src kinase
4145 MATK; megakaryocyte-associated tyrosine kinase
5747 PTK2; protein tyrosine kinase 2
2185 PTK2B; protein tyrosine kinase 2 beta
2242 FES; FES proto-oncogene, tyrosine kinase
2241 FER; FER tyrosine kinase
3716 JAK1; Janus kinase 1
3717 JAK2; Janus kinase 2
3718 JAK3; Janus kinase 3
7297 TYK2; tyrosine kinase 2
640 BLK; BLK proto-oncogene, Src family tyrosine kinase
2268 FGR; FGR proto-oncogene, Src family tyrosine kinase
2444 FRK; fyn related Src family tyrosine kinase
2534 FYN; FYN proto-oncogene, Src family tyrosine kinase
3055 HCK; HCK proto-oncogene, Src family tyrosine kinase
4067 LYN; LYN proto-oncogene, Src family tyrosine kinase
3932 LCK; LCK proto-oncogene, Src family tyrosine kinase
5753 PTK6; protein tyrosine kinase 6
6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase
6725 SRMS; src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites
7525 YES1; YES proto-oncogene 1, Src family tyrosine kinase
660 BMX; BMX non-receptor tyrosine kinase
695 BTK; Bruton tyrosine kinase
3702 ITK; IL2 inducible T cell kinase
7006 TEC; tec protein tyrosine kinase
7294 TXK; TXK tyrosine kinase
6850 SYK; spleen associated tyrosine kinase
7535 ZAP70; zeta chain of T cell receptor associated protein kinase 70
55359 STYK1; serine/threonine/tyrosine kinase 1
91461 PKDCC; protein kinase domain containing, cytoplasmic
|
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K19584 PRKX; protein kinase X [EC:2.7.11.11]
K07376 PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]
K19477 PRKG2; cGMP-dependent protein kinase 2 [EC:2.7.11.12]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K18051 PRKCH; novel protein kinase C eta type [EC:2.7.11.13]
K18052 PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K06069 PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]
K06071 PKN1; serine/threonine-protein kinase N1 [EC:2.7.11.13]
K23691 PKN2; serine/threonine-protein kinase N2 [EC:2.7.11.13]
K23692 PKN3; serine/threonine-protein kinase N3 [EC:2.7.11.13]
K11481 AURKA; aurora kinase A [EC:2.7.11.1]
K11479 AURKB; aurora kinase B [EC:2.7.11.1]
K11480 AURKC; aurora kinase C [EC:2.7.11.1]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K13302 SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
K13303 SGK2; serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
K13304 SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
K13304 SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K16510 RPS6KA4; ribosomal protein S6 kinase alpha-4 [EC:2.7.11.1]
K04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K20839 RSKL; ribosomal protein S6 kinase-like
K20839 RSKL; ribosomal protein S6 kinase-like
K08790 STK38; serine/threonine kinase 38 [EC:2.7.11.1]
K08790 STK38; serine/threonine kinase 38 [EC:2.7.11.1]
K08791 LATS1_2; serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1]
K08791 LATS1_2; serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1]
K08789 MAST; MAST-subfamily protein kinase [EC:2.7.11.37]
K08789 MAST; MAST-subfamily protein kinase [EC:2.7.11.37]
K08789 MAST; MAST-subfamily protein kinase [EC:2.7.11.37]
K08789 MAST; MAST-subfamily protein kinase [EC:2.7.11.37]
K16309 MASTL; serine/threonine-protein kinase greatwall [EC:2.7.11.36]
K08793 STK32; serine/threonine kinase 32 [EC:2.7.11.1]
K08793 STK32; serine/threonine kinase 32 [EC:2.7.11.1]
K08793 STK32; serine/threonine kinase 32 [EC:2.7.11.1]
K08788 DMPK; dystrophia myotonica-protein kinase [EC:2.7.11.1]
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K16307 CDC42BP; serine/threonine-protein kinase MRCK [EC:2.7.11.1]
K16307 CDC42BP; serine/threonine-protein kinase MRCK [EC:2.7.11.1]
K16307 CDC42BP; serine/threonine-protein kinase MRCK [EC:2.7.11.1]
K16308 CIT; citron Rho-interacting kinase [EC:2.7.11.35]
K00909 GRK1_7; rhodopsin kinase [EC:2.7.11.14]
K00909 GRK1_7; rhodopsin kinase [EC:2.7.11.14]
K00910 ADRBK; beta-adrenergic-receptor kinase [EC:2.7.11.15]
K00910 ADRBK; beta-adrenergic-receptor kinase [EC:2.7.11.15]
K08291 GRK4_5_6; G protein-coupled receptor kinase [EC:2.7.11.16]
K08291 GRK4_5_6; G protein-coupled receptor kinase [EC:2.7.11.16]
K08291 GRK4_5_6; G protein-coupled receptor kinase [EC:2.7.11.16]
K17529 SGK494; uncharacterized serine/threonine-protein kinase SgK494 [EC:2.7.11.1]
K08794 CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
K08794 CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
K08794 CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
K05869 CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
K08795 PNCK; pregnancy upregulated non-ubiquitously expressed CaM kinase [EC:2.7.11.17]
K08812 CAMKV; CaM kinase-like vesicle-associated [EC:2.7.11.-]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K08796 BRSK; BR serine/threonine kinase [EC:2.7.11.1]
K08796 BRSK; BR serine/threonine kinase [EC:2.7.11.1]
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K08797 HUNK; hormonally upregulated Neu-associated kinase [EC:2.7.11.1]
K08798 MARK; MAP/microtubule affinity-regulating kinase [EC:2.7.11.1]
K08798 MARK; MAP/microtubule affinity-regulating kinase [EC:2.7.11.1]
K08798 MARK; MAP/microtubule affinity-regulating kinase [EC:2.7.11.1]
K08798 MARK; MAP/microtubule affinity-regulating kinase [EC:2.7.11.1]
K08799 MELK; maternal embryonic leucine zipper kinase [EC:2.7.11.1]
K16310 NIM1; serine/threonine-protein kinase NIM1 [EC:2.7.11.1]
K08800 NUAK; NUAK family, SNF1-like kinase [EC:2.7.11.1]
K08800 NUAK; NUAK family, SNF1-like kinase [EC:2.7.11.1]
K08801 PASK; PAS domain containing serine/threonine kinase [EC:2.7.11.1]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K19008 SIK1; serine/threonine-protein kinase SIK1 [EC:2.7.11.1]
K19008 SIK1; serine/threonine-protein kinase SIK1 [EC:2.7.11.1]
K16311 SIK2; serine/threonine-protein kinase SIK2 [EC:2.7.11.1]
K19009 SIK3; serine/threonine-protein kinase SIK3 [EC:2.7.11.1]
K08802 SNRK; SNF related kinase [EC:2.7.11.1]
K07298 STK11; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08804 STK17; serine/threonine kinase 17 [EC:2.7.11.1]
K08804 STK17; serine/threonine kinase 17 [EC:2.7.11.1]
K08805 DCLK1_2; doublecortin-like kinase 1/2 [EC:2.7.11.1]
K08805 DCLK1_2; doublecortin-like kinase 1/2 [EC:2.7.11.1]
K17530 DCLK3; doublecortin-like kinase 3 [EC:2.7.11.1]
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K04444 MAPKAPK3; mitogen-activated protein kinase-activated protein kinase 3 [EC:2.7.11.1]
K04442 MAPKAPK5; mitogen-activated protein kinase-activated protein kinase 5 [EC:2.7.11.1]
K04372 MKNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
K04372 MKNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K12567 TTN; titin [EC:2.7.11.1]
K00871 PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]
K00871 PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K08806 PIM2; proto-oncogene serine/threonine-protein kinase Pim-2 [EC:2.7.11.1]
K08807 PIM3; proto-oncogene serine/threonine-protein kinase Pim-3 [EC:2.7.11.1]
K06070 PKD; protein kinase D [EC:2.7.11.13]
K06070 PKD; protein kinase D [EC:2.7.11.13]
K06070 PKD; protein kinase D [EC:2.7.11.13]
K08808 PSKH; protein serine kinase H [EC:2.7.11.1]
K08808 PSKH; protein serine kinase H [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K08809 SPEG; striated muscle-specific serine/threonine protein kinase [EC:2.7.11.1]
K08810 TRIO; triple functional domain protein [EC:2.7.11.1]
K15048 KALRN; kalirin [EC:2.7.11.1]
K17531 OBSCN; obscurin-RhoGEF [EC:2.7.11.1]
K08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]
K08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]
K08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]
K08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]
K08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]
K06103 CASK; calcium/calmodulin-dependent serine protein kinase [EC:2.7.11.1]
K08814 TRIB1_2; tribbles homolog 1/2
K08814 TRIB1_2; tribbles homolog 1/2
K19518 TRIB3; tribbles homolog 3
K08813 STK33; serine/threonine kinase 33 [EC:2.7.11.1]
K16312 STK40; serine/threonine-protein kinase 40 [EC:2.7.11.1]
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K08958 CSNK1G; casein kinase 1, gamma [EC:2.7.11.1]
K08958 CSNK1G; casein kinase 1, gamma [EC:2.7.11.1]
K08958 CSNK1G; casein kinase 1, gamma [EC:2.7.11.1]
K08959 CSNK1D; casein kinase 1, delta [EC:2.7.11.1]
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K08815 TTBK; tau tubulin kinase [EC:2.7.11.26]
K08815 TTBK; tau tubulin kinase [EC:2.7.11.26]
K08816 VRK; vaccinia related kinase [EC:2.7.11.1]
K08816 VRK; vaccinia related kinase [EC:2.7.11.1]
K08816 VRK; vaccinia related kinase [EC:2.7.11.1]
K08817 CCRK; cell cycle related kinase [EC:2.7.11.22]
K08818 CDC2L; cell division cycle 2-like [EC:2.7.11.22]
K08818 CDC2L; cell division cycle 2-like [EC:2.7.11.22]
K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K02088 CDK3; cyclin-dependent kinase 3 [EC:2.7.11.22]
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02090 CDK5; cyclin-dependent kinase 5 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
K02208 CDK8_11; cyclin-dependent kinase 8/11 [EC:2.7.11.22 2.7.11.23]
K02208 CDK8_11; cyclin-dependent kinase 8/11 [EC:2.7.11.22 2.7.11.23]
K02211 CDK9; cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23]
K02449 CDK10; cyclin-dependent kinase 10 [EC:2.7.11.22]
K08819 CDK12_13; cyclin-dependent kinase 12/13 [EC:2.7.11.22 2.7.11.23]
K08819 CDK12_13; cyclin-dependent kinase 12/13 [EC:2.7.11.22 2.7.11.23]
K08821 CDK14; cyclin-dependent kinase 14 [EC:2.7.11.22]
K15594 CDK15; cyclin-dependent kinase 15 [EC:2.7.11.22]
K08820 CDK16; cyclin-dependent kinase 16 [EC:2.7.11.22]
K15595 CDK17; cyclin-dependent kinase 17 [EC:2.7.11.22]
K15596 CDK18; cyclin-dependent kinase 18 [EC:2.7.11.22]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K06855 MAPK4_6; mitogen-activated protein kinase 4/6 [EC:2.7.11.24]
K06855 MAPK4_6; mitogen-activated protein kinase 4/6 [EC:2.7.11.24]
K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K19603 MAPK15; mitogen-activated protein kinase 15 [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04468 NLK; nemo like kinase [EC:2.7.11.24]
K08822 GSK3A; glycogen synthase kinase 3 alpha [EC:2.7.11.26]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K23561 CLK1_4; dual specificity protein kinase CLK1/4 [EC:2.7.12.1]
K23561 CLK1_4; dual specificity protein kinase CLK1/4 [EC:2.7.12.1]
K08823 CLK2_3; dual specificity protein kinase CLK2/3 [EC:2.7.12.1]
K08823 CLK2_3; dual specificity protein kinase CLK2/3 [EC:2.7.12.1]
K08824 CDKL; cyclin-dependent kinase-like [EC:2.7.11.22]
K08824 CDKL; cyclin-dependent kinase-like [EC:2.7.11.22]
K08824 CDKL; cyclin-dependent kinase-like [EC:2.7.11.22]
K08824 CDKL; cyclin-dependent kinase-like [EC:2.7.11.22]
K08824 CDKL; cyclin-dependent kinase-like [EC:2.7.11.22]
K08825 DYRK1; dual specificity tyrosine-phosphorylation-regulated kinase 1 [EC:2.7.12.1]
K08825 DYRK1; dual specificity tyrosine-phosphorylation-regulated kinase 1 [EC:2.7.12.1]
K18669 DYRK2_3_4; dual specificity tyrosine-phosphorylation-regulated kinase 2/3/4 [EC:2.7.12.1]
K18669 DYRK2_3_4; dual specificity tyrosine-phosphorylation-regulated kinase 2/3/4 [EC:2.7.12.1]
K18669 DYRK2_3_4; dual specificity tyrosine-phosphorylation-regulated kinase 2/3/4 [EC:2.7.12.1]
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K08827 PRPF4B; serine/threonine-protein kinase PRP4 [EC:2.7.11.1]
K08828 ICK; intestinal cell (MAK-like) kinase [EC:2.7.11.22]
K08829 MAK; male germ cell-associated kinase [EC:2.7.11.22]
K08830 RAGE; renal tumor antigen [EC:2.7.11.22]
K15409 SRPK1; serine/threonine-protein kinase SRPK1 [EC:2.7.11.1]
K08831 SRPK2; serine/threonine-protein kinase SRPK2 [EC:2.7.11.1]
K08832 SRPK3; serine/threonine-protein kinase SRPK3 [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04432 MAP2K3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04463 MAP2K5; mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
K04433 MAP2K6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04408 MAP4K1; mitogen-activated protein kinase kinase kinase kinase 1 [EC:2.7.11.1]
K04414 MAP4K2; mitogen-activated protein kinase kinase kinase kinase 2 [EC:2.7.11.1]
K04406 MAP4K3; mitogen-activated protein kinase kinase kinase kinase 3 [EC:2.7.11.1]
K04407 MAP4K4; mitogen-activated protein kinase kinase kinase kinase 4 [EC:2.7.11.1]
K08833 MAP4K5; mitogen-activated protein kinase kinase kinase kinase 5 [EC:2.7.11.1]
K04413 MINK; misshapen/NIK-related kinase [EC:2.7.11.1]
K08840 TNIK; TRAF2 and NCK interacting kinase [EC:2.7.11.1]
K16313 NRK; Nik-related protein kinase [EC:2.7.11.1]
K08834 MYO3; myosin III [EC:2.7.11.1]
K08834 MYO3; myosin III [EC:2.7.11.1]
K08835 OXSR1; serine/threonine-protein kinase OSR1/STK39 [EC:2.7.11.1]
K08835 OXSR1; serine/threonine-protein kinase OSR1/STK39 [EC:2.7.11.1]
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K08836 SLK; STE20-like kinase [EC:2.7.11.1]
K08837 STK10; serine/threonine kinase 10 [EC:2.7.11.1]
K08271 STRADA; STE20-related kinase adapter protein alpha
K17532 STRADB; STE20-related kinase adapter protein beta
K04412 STK3; serine/threonine kinase 3
K04411 STK4; serine/threonine kinase 4
K08838 STK24_25_MST4; serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1]
K08838 STK24_25_MST4; serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1]
K08838 STK24_25_MST4; serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1]
K04429 TAO; thousand and one amino acid protein kinase [EC:2.7.11.1]
K04429 TAO; thousand and one amino acid protein kinase [EC:2.7.11.1]
K04429 TAO; thousand and one amino acid protein kinase [EC:2.7.11.1]
K04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K04420 MAP3K2; mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25]
K04421 MAP3K3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
K04428 MAP3K4; mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25]
K04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04425 MAP3K6; mitogen-activated protein kinase kinase kinase 6 [EC:2.7.11.25]
K13986 MAP3K15; mitogen-activated protein kinase kinase kinase 15 [EC:2.7.11.25]
K17533 MAP3K19; mitogen-activated protein kinase kinase kinase 19 [EC:2.7.11.25]
K04415 MAP3K8; mitogen-activated protein kinase kinase kinase 8 [EC:2.7.11.25]
K04466 MAP3K14; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04731 IRAK2; interleukin-1 receptor-associated kinase 2 [EC:2.7.11.1]
K04732 IRAK3; interleukin-1 receptor-associated kinase 3 [EC:2.7.11.1]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K05743 LIMK1; LIM domain kinase 1 [EC:2.7.11.1]
K05744 LIMK2; LIM domain kinase 2 [EC:2.7.11.1]
K08841 TESK1; testis-specific kinase 1 [EC:2.7.12.1]
K08842 TESK2; testis-specific kinase 2 [EC:2.7.12.1]
K08843 LRRK1; leucine-rich repeat kinase 1 [EC:2.7.11.1]
K08844 LRRK2; leucine-rich repeat kinase 2 [EC:2.7.11.1]
K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04417 MAP3K9; mitogen-activated protein kinase kinase kinase 9 [EC:2.7.11.25]
K04418 MAP3K10; mitogen-activated protein kinase kinase kinase 10 [EC:2.7.11.25]
K04419 MAP3K11; mitogen-activated protein kinase kinase kinase 11 [EC:2.7.11.25]
K17534 MLK4; mitogen-activated protein kinase kinase kinase MLK4 [EC:2.7.11.25]
K04424 ZAK; sterile alpha motif and leucine zipper containing kinase AZK [EC:2.7.11.25]
K04423 MAP3K12; mitogen-activated protein kinase kinase kinase 12 [EC:2.7.11.25]
K04422 MAP3K13; mitogen-activated protein kinase kinase kinase 13 [EC:2.7.11.25]
K17535 TNNI3K; serine/threonine-protein kinase TNNI3K [EC:2.7.11.1]
K17535 TNNI3K; serine/threonine-protein kinase TNNI3K [EC:2.7.11.1]
K06272 ILK; integrin-linked kinase [EC:2.7.11.1]
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K14958 KSR1; kinase suppressor of Ras 1
K18529 KSR2; kinase suppressor of Ras 2 [EC:2.7.11.1]
K02861 RIPK1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K08846 RIPK2; receptor-interacting serine/threonine-protein kinase 2 [EC:2.7.11.1]
K08847 RIPK3; receptor-interacting serine/threonine-protein kinase 3 [EC:2.7.11.1]
K08848 RIPK4; receptor-interacting serine/threonine-protein kinase 4 [EC:2.7.11.1]
K16289 ANKK1; ankyrin repeat and protein kinase domain-containing protein 1 [EC:2.7.11.1]
K08849 MLKL; mixed lineage kinase domain-like [EC:2.7.11.1]
K12323 ANPRA; atrial natriuretic peptide receptor A [EC:4.6.1.2]
K12324 ANPRB; atrial natriuretic peptide receptor B [EC:4.6.1.2]
K12320 GUCY2C; heat-stable enterotoxin receptor [EC:4.6.1.2]
K12321 GUCY2D_E; guanylate cyclase 2D/E [EC:4.6.1.2]
K12322 GUCY2F; guanylate cyclase 2F [EC:4.6.1.2]
K02178 BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
K06637 BUB1B; mitotic checkpoint serine/threonine-protein kinase BUB1 beta [EC:2.7.11.1]
K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
K00908 CAMKK1; calcium/calmodulin-dependent protein kinase kinase 1 [EC:2.7.11.17]
K07359 CAMKK2; calcium/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]
K02214 CDC7; cell division control protein 7 [EC:2.7.11.1]
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K16315 GSG2; serine/threonine-protein kinase haspin [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K07211 IKBKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K08852 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
K11715 ERN2; serine/threonine-protein kinase/endoribonuclease IRE2 [EC:2.7.11.1 3.1.26.-]
K04367 MOS; proto-oncogene serine/threonine-protein kinase mos [EC:2.7.11.1]
K08853 AAK; AP2-associated kinase [EC:2.7.11.1]
K08854 BMP2K; BMP2 inducible kinase [EC:2.7.11.1]
K08855 GAK; cyclin G-associated kinase [EC:2.7.11.1]
K08856 STK16; serine/threonine kinase 16 [EC:2.7.11.1]
K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
K20872 NEK2; serine/threonine-protein kinase Nek2 [EC:2.7.11.1]
K20873 NEK3; serine/threonine-protein kinase Nek3 [EC:2.7.11.1]
K20875 NEK6; serine/threonine-protein kinase Nek6 [EC:2.7.11.34]
K20876 NEK7; serine/threonine-protein kinase Nek7 [EC:2.7.11.34]
K20877 NEK8; serine/threonine-protein kinase Nek8 [EC:2.7.11.1]
K20878 NEK9; serine/threonine-protein kinase Nek9 [EC:2.7.11.1]
K20879 NEK10; serine/threonine-protein kinase Nek10 [EC:2.7.11.1]
K20880 NEK11; serine/threonine-protein kinase Nek11 [EC:2.7.11.1]
K08858 SBK; serine/threonine-protein kinase SBK [EC:2.7.11.1]
K08858 SBK; serine/threonine-protein kinase SBK [EC:2.7.11.1]
K08858 SBK; serine/threonine-protein kinase SBK [EC:2.7.11.1]
K05688 PINK1; PTEN induced putative kinase 1 [EC:2.7.11.1]
K17537 SGK223; tyrosine-protein kinase SgK223 [EC:2.7.10.2]
K17538 PEAK1; pseudopodium-enriched atypical kinase 1 [EC:2.7.10.2]
K08859 STK35; serine/threonine kinase 35 [EC:2.7.11.1]
K17539 PDIK1L; serine/threonine-protein kinase PDIK1L [EC:2.7.11.1]
K17540 TEX14; inactive serine/threonine-protein kinase TEX14
K08875 NRBP; nuclear receptor-binding protein
K08875 NRBP; nuclear receptor-binding protein
K16194 EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1 [EC:2.7.11.1]
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
K08860 EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K16196 EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]
K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
K08861 PLK2; polo-like kinase 2 [EC:2.7.11.21]
K08862 PLK3; polo-like kinase 3 [EC:2.7.11.21]
K08863 PLK4; polo-like kinase 4 [EC:2.7.11.21]
K08876 SCYL1; SCY1-like protein 1
K17541 SCYL2; SCY1-like protein 2
K17542 SCYL3; SCY1-like protein 3
K17543 PXK; PX domain-containing protein kinase-like protein
K17544 TBCK; TBC domain-containing protein kinase-like protein
K08864 TLK; tousled-like kinase [EC:2.7.11.1]
K08864 TLK; tousled-like kinase [EC:2.7.11.1]
K08865 PBK; PDZ-binding kinase [EC:2.7.12.2]
K08866 TTK; serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]
K06228 FU; fused [EC:2.7.11.1]
K21357 ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
K08269 ULK2; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
K21358 ULK3; serine/threonine-protein kinase ULK3 [EC:2.7.11.1]
K17545 ULK4; serine/threonine-protein kinase ULK4 [EC:2.7.11.1]
K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
K06633 PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1]
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K08867 WNK; WNK lysine deficient protein kinase [EC:2.7.11.1]
K08867 WNK; WNK lysine deficient protein kinase [EC:2.7.11.1]
K08867 WNK; WNK lysine deficient protein kinase [EC:2.7.11.1]
K08867 WNK; WNK lysine deficient protein kinase [EC:2.7.11.1]
K08869 ADCK; aarF domain-containing kinase
K08869 ADCK; aarF domain-containing kinase
K08869 ADCK; aarF domain-containing kinase
K08869 ADCK; aarF domain-containing kinase
K08869 ADCK; aarF domain-containing kinase
K08868 ALPK; alpha-kinase
K08868 ALPK; alpha-kinase
K08868 ALPK; alpha-kinase
K04981 TRPM6; transient receptor potential cation channel subfamily M member 6 [EC:2.7.11.1]
K04982 TRPM7; transient receptor potential cation channel subfamily M member 7 [EC:2.7.11.1]
K08292 EEF2K; elongation factor 2 kinase [EC:2.7.11.20]
K08878 BCR1; breakpoint cluster region protein [EC:2.7.11.1]
K08871 BRD2; bromodomain-containing protein 2
K11721 BRD3; bromodomain-containing protein 3
K11722 BRD4; bromodomain-containing protein 4
K11724 BRDT; bromodomain testis-specific protein
K08290 FASTK; Fas-activated serine/threonine kinase [EC:2.7.11.8]
K08880 STK19; serine/threonine kinase 19 [EC:2.7.11.1]
K08879 HSPB8; heat shock protein beta-8
K12077 PDK1; pyruvate dehydrogenase kinase isoform 1 [EC:2.7.11.2]
K00898 PDK2_3_4; pyruvate dehydrogenase kinase 2/3/4 [EC:2.7.11.2]
K00898 PDK2_3_4; pyruvate dehydrogenase kinase 2/3/4 [EC:2.7.11.2]
K00898 PDK2_3_4; pyruvate dehydrogenase kinase 2/3/4 [EC:2.7.11.2]
K00905 BCKDK; [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase [EC:2.7.11.4]
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
K08874 TRRAP; transformation/transcription domain-associated protein
K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]
K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]
K08872 RIOK3; RIO kinase 3 [EC:2.7.11.1]
K03125 TAF1; transcription initiation factor TFIID subunit 1 [EC:2.3.1.48 2.7.11.1]
K03125 TAF1; transcription initiation factor TFIID subunit 1 [EC:2.3.1.48 2.7.11.1]
K08060 CIITA; MHC class II transactivator [EC:2.7.11.1]
K08881 TRIM24; tripartite motif-containing protein 24 [EC:2.3.2.27]
K08882 TRIM28; tripartite motif-containing protein 28 [EC:2.3.2.27]
K08883 TRIM33; tripartite motif-containing protein 33 [EC:2.3.2.27]
K08877 UHMK1; serine/threonine-protein kinase Kist [EC:2.7.11.1]
K11789 DCAF1; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]
K16316 STK31; serine/threonine-protein kinase 31 [EC:2.7.11.1]
K17547 SGK196; glycoprotein-mannosyl O6-kinase [EC:2.7.1.183]
K16288 DSTYK; dual serine/threonine and tyrosine protein kinase [EC:2.7.12.1]
K17546 STKLD1; serine/threonine kinase-like domain-containing protein STKLD1
K04675 ACVR1; activin receptor type-1 [EC:2.7.11.30]
K13594 ACVRL1; activin receptor-like kinase 1 [EC:2.7.11.30]
K13567 ACVR1B; activin receptor type-1B [EC:2.7.11.30]
K13568 ACVR1C; activin receptor type-1C [EC:2.7.11.30]
K04673 BMPR1A; bone morphogenetic protein receptor type-1A [EC:2.7.11.30]
K13578 BMPR1B; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04670 ACVR2A; activin receptor type-2A [EC:2.7.11.30]
K13596 ACVR2B; activin receptor type-2B [EC:2.7.11.30]
K04672 AMHR2; anti-mullerian hormone receptor type-2 [EC:2.7.11.30]
K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05084 ERBB3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K05085 ERBB4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
K05086 INSRR; insulin receptor-related receptor [EC:2.7.10.1]
K04527 INSR; insulin receptor [EC:2.7.10.1]
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05090 CSF1R; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K05091 KIT; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05092 FLT3; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K05096 FLT1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05097 FLT4; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K05098 KDR; kinase insert domain protein receptor [EC:2.7.10.1]
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05100 MST1R; macrophage-stimulating 1 receptor [EC:2.7.10.1]
K03176 NTRK1; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K04360 NTRK2; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
K05101 NTRK3; neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1]
K05102 EPHA1; Eph receptor A1 [EC:2.7.10.1]
K05103 EPHA2; Eph receptor A2 [EC:2.7.10.1]
K05104 EPHA3; Eph receptor A3 [EC:2.7.10.1]
K05105 EPHA4; Eph receptor A4 [EC:2.7.10.1]
K05106 EPHA5; Eph receptor A5 [EC:2.7.10.1]
K05107 EPHA6; Eph receptor A6 [EC:2.7.10.1]
K05108 EPHA7; EphA7 [EC:2.7.10.1]
K05109 EPHA8; Eph receptor A8 [EC:2.7.10.1]
K08897 EPHA10; Eph receptor A10 [EC:2.7.10.1]
K05110 EPHB1; Eph receptor B1 [EC:2.7.10.1]
K05111 EPHB2; Eph receptor B2 [EC:2.7.10.1]
K05112 EPHB3; Eph receptor B3 [EC:2.7.10.1]
K05113 EPHB4; Eph receptor B4 [EC:2.7.10.1]
K05114 EPHB6; Eph receptor B6 [EC:2.7.10.1]
K05115 AXL; AXL receptor tyrosine kinase [EC:2.7.10.1]
K05116 TYRO3; TYRO3 protein tyrosine kinase 3 [EC:2.7.10.1]
K05117 MERTK; c-mer proto-oncogene tyrosine kinase [EC:2.7.10.1]
K05119 ALK; anaplastic lymphoma kinase [EC:2.7.10.1]
K05118 LTK; leukocyte tyrosine kinase [EC:2.7.10.1]
K05120 TIE1; tyrosine kinase receptor 1 [EC:2.7.10.1]
K05121 TEK; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
K05122 ROR1; receptor tyrosine kinase-like orphan receptor 1 [EC:2.7.10.1]
K05123 ROR2; receptor tyrosine kinase-like orphan receptor 2 [EC:2.7.10.1]
K05124 DDR1; discoidin domain receptor family member 1 [EC:2.7.10.1]
K05125 DDR2; discoidin domain receptor family member 2 [EC:2.7.10.1]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K05088 ROS1; proto-oncogene tyrosine-protein kinase ROS [EC:2.7.10.1]
K05127 PTK7; PTK7 protein tyrosine kinase 7 [EC:2.7.10.1]
K05128 RYK; RYK receptor-like tyrosine kinase [EC:2.7.10.1]
K05129 MUSK; muscle, skeletal, receptor tyrosine kinase [EC:2.7.10.1]
K17480 AATK; lemur tyrosine kinase 1 [EC:2.7.10.1]
K08898 LMTK2; lemur tyrosine kinase 2 [EC:2.7.10.1]
K08899 LMTK3; lemur tyrosine kinase 3 [EC:2.7.10.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K08887 ABL2; abelson tyrosine-protein kinase 2 [EC:2.7.10.2]
K08885 TNK1; non-receptor tyrosine-protein kinase TNK1 [EC:2.7.10.2]
K08886 TNK2; activated CDC42 kinase 1 [EC:2.7.10.2 2.7.11.1]
K05728 CSK; c-src tyrosine kinase [EC:2.7.10.2]
K08888 MATK; megakaryocyte-associated tyrosine kinase [EC:2.7.10.2]
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K05871 PTK2B; focal adhesion kinase 2 [EC:2.7.10.2]
K07527 FES; tyrosine-protein kinase Fes/Fps [EC:2.7.10.2]
K08889 FER; tyrosine-protein kinase Fer [EC:2.7.10.2]
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K08890 BLK; B lymphoid tyrosine kinase [EC:2.7.10.2]
K08891 FGR; tyrosine-protein kinase Fgr [EC:2.7.10.2]
K08892 FRK; fyn-related kinase [EC:2.7.10.2]
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K08893 HCK; hemopoietic cell kinase [EC:2.7.10.2]
K05854 LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K08894 PTK6; protein tyrosine kinase 6 [EC:2.7.10.2]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K08895 SRMS; tyrosine-protein kinase Srms [EC:2.7.10.2]
K05705 YES1; tyrosine-protein kinase Yes [EC:2.7.10.2]
K08896 BMX; cytoplasmic tyrosine-protein kinase BMX [EC:2.7.10.2]
K07370 BTK; Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2]
K07363 ITK; IL2-inducible T-cell kinase [EC:2.7.10.2]
K07364 TEC; tyrosine-protein kinase Tec [EC:2.7.10.2]
K08016 TXK; tyrosine-protein kinase TXK [EC:2.7.10.2]
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K17510 STYK1; tyrosine-protein kinase STYK1 [EC:2.7.10.2]
K17548 PKDCC; extracellular tyrosine-protein kinase PKDCC [EC:2.7.10.2]
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01009 Protein phosphatases and associated proteins [BR:hsa01009]
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01002 Peptidases and inhibitors [BR:hsa01002]
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01003 Glycosyltransferases [BR:hsa01003]
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01005 Lipopolysaccharide biosynthesis proteins
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01011 Peptidoglycan biosynthesis and degradation proteins
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01004 Lipid biosynthesis proteins [BR:hsa01004]
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01008 Polyketide biosynthesis proteins
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01006 Prenyltransferases [BR:hsa01006]
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01007 Amino acid related enzymes [BR:hsa01007]
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00199 Cytochrome P450 [BR:hsa00199]
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00194 Photosynthesis proteins
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09182 Protein families: genetic information processing
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09183 Protein families: signaling and cellular processes
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09185 Viral protein families
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09184 RNA family
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09190 Not Included in Pathway or Brite
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KEGG Orthology (KO) - Homo sapiens (human)